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https://www.readbyqxmd.com/read/28801883/prognostic-utility-of-fatty-acid-binding-protein-4-in-patients-with-type-2-diabetes-and-acute-ischemic-stroke
#1
Siou Li, Pengxiang Bi, Weina Zhao, Yifei Lian, Haifu Zhu, Dan Xu, Jiayuan Ding, Quankui Wang, Changhao Yin
The role of fatty acid-binding proteins (FABPs) in atherosclerosis has been investigated. The aim of this study was to verify the hypothesis that higher levels of serum fatty acid-binding protein 4 (FABP4) could be a prognostic factor in Chinese patients with type 2 diabetes (T2DM) and acute ischemic stroke (AIS). From September 2015 to August 2016, consecutive first-ever AIS patients combined with T2DM were included in this study. FABP4, NIH stroke scale (NIHSS), and conventional risk factors were evaluated to determine their value to predict functional outcomes within 3 months...
August 11, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/28801846/vascular-function-in-breast-cancer-survivors-on-aromatase-inhibitors-a-pilot-study
#2
Anne Blaes, Heather Beckwith, Natalia Florea, Robert Hebbel, Anna Solovey, David Potter, Douglas Yee, Rachel Vogel, Russell Luepker, Daniel Duprez
PURPOSE: Aromatase inhibitors (AI) have been shown to reduce breast cancer-related mortality in women with estrogen positive (ER+) breast cancer. The use of AIs, however, has been associated with higher rates of hypertension, hyperlipidemia, and cardiovascular (CV) events. METHODS: A cross-sectional study of 25 healthy postmenopausal women and 36 women with curative intent breast cancer on an AI was performed to assess endothelial dysfunction, an indicator of risk for CV events...
August 11, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28800763/causes-trends-and-severity-of-musculoskeletal-injuries-in-ghana
#3
Eric Lawer Torgbenu, Emmanuel K Nakua, Henry Kyei, Eric Badu, Maxwell Peprah Opoku
BACKGROUND: Musculoskeletal [MSK] injuries are common causes of long-term pain and physical disability which affect many people worldwide. The economic and social impacts on the individual, society and national health systems are enormous making a matter of public health concern. Therefore, this study examined the causes and extent of MSK injuries in a referral hospital in Ghana. METHODS: A prospective study design with consecutive sampling method was used to recruit patients admitted at Trauma Unit as well as those receiving orthopaedic reviews at St...
August 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28800651/vertical-macular-asymmetry-measures-derived-from-sd-oct-for-detection-of-early-glaucoma
#4
Farideh Sharifipour, Esteban Morales, Ji Woong Lee, JoAnn Giaconi, Abdelmonem A Afifi, Fei Yu, Joseph Caprioli, Kouros Nouri-Mahdavi
Purpose: To test the hypothesis that vertical asymmetry in macular ganglion cell/inner plexiform layer (GCIPL) thickness can improve detection of early glaucoma. Methods: Sixty-nine normal eyes and 101 glaucoma eyes had macular imaging with spectral-domain optical coherence tomography (OCT; 200 × 200 cube). The resulting GCIPL thickness matrix was grouped into a 20 × 20 superpixel array and superior superpixels were compared to their inferior counterparts. A global asymmetry index (AI) was defined as the grand mean of the asymmetry ratios...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28800571/long-term-pulmonary-function-after-open-anterior-thoracolumbar-surgery-in-thoracolumbar-lumbar-idiopathic-adolescent-scoliosis
#5
Cristina Ruiz-Juretschke, Javier Pizones, Renato Delfino, Felisa Sánchez-Mariscal, Lorenzo Zúñiga, Enrique Izquierdo
STUDY DESIGN: A prospectively updated, long-term case series analysis. OBJECTIVE: The aim of this study was to report the effect of thoracolumbar anterior open surgery performed during adolescence on adult pulmonary function. SUMMARY OF BACKGROUND DATA: There seems to be subclinical impairment of pulmonary function in the mid-term (2-5 years) in patients who underwent thoracotomy or thoraco-phreno-laparotomy after adolescent idiopathic scoliosis (AIS) surgery...
August 15, 2017: Spine
https://www.readbyqxmd.com/read/28799181/the-relationship-between-stroke-severity-and-prior-direct-oral-anticoagulant-therapy-in-patients-with-acute-ischemic-stroke-and-non-valvular-atrial-fibrillation
#6
Yuki Sakamoto, Seiji Okubo, Chikako Nito, Satoshi Suda, Noriko Matsumoto, Arata Abe, Junya Aoki, Takashi Shimoyama, Yohei Takayama, Kentaro Suzuki, Masahiro Mishina, Kazumi Kimura
BACKGROUND: Anticoagulant treatment with a vitamin K antagonist (VKA) has been reported to reduce stroke severity when patients with atrial fibrillation (AF) suffer acute ischemic stroke (AIS). Direct oral anticoagulant (DOAC) therapy also has a potential to reduce the initial severity of AIS. However, the effect of DOAC therapy on the severity of AIS is not well known. The aims of the present study were to investigate the effect of DOACs on initial stroke severity in patients with AIS and non-valvular AF (NVAF)...
August 11, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28798984/midlife-changes-of-health-related-quality-of-life-in-adolescent-idiopathic-scoliosis-patients-who-underwent-spinal-fusion-during-adolescence
#7
Tsutomu Akazawa, Toshiaki Kotani, Tsuyoshi Sakuma, Shohei Minami, Yoshiaki Torii, Sumihisa Orita, Kazuhide Inage, Kazuki Fujimoto, Yasuhiro Shiga, Gen Inoue, Masayuki Miyagi, Wataru Saito, Seiji Ohtori, Hisateru Niki
PURPOSE: Our previous study reported a good health-related quality of life (HRQOL) in adolescent idiopathic scoliosis (AIS) patients 21 years or more after surgery. The purpose of this study is to investigate midlife changes in HRQOL among AIS patients who passed further 5 years from the previous survey. METHODS: Subjects were 252 individuals who underwent spinal fusion for AIS between 1968 and 1988. The survey was administered twice-in 2009 and in 2014 using Scoliosis Research Society Patient Questionnaire (SRS-22)...
August 10, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28798267/pretreatment-predictors-of-malignant-evolution-in-patients-with-ischemic-stroke-undergoing-mechanical-thrombectomy
#8
Alessandro Davoli, Caterina Motta, Giacomo Koch, Marina Diomedi, Simone Napolitano, Angela Giordano, Marta Panella, Daniele Morosetti, Sebastiano Fabiano, Roberto Floris, Roberto Gandini, Fabrizio Sallustio
BACKGROUND: Few data exist on malignant middle cerebral artery infarction (MMI) among patients with acute ischemic stroke (AIS) after endovascular treatment (ET). Numerous predictors of MMI evolution have been proposed, but a comprehensive research of patients undergoing ET has never been performed. Our purpose was to find a practical model to determine robust predictors of MMI in patients undergoing ET. METHODS: Patients from a prospective single-center database with AIS secondary to large intracranial vessel occlusion of the anterior circulation, treated with ET, were retrospectively analyzed...
August 10, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28797154/-to-analyse-the-histopathological-results-of-patients-with-hpv16-18-positive-and-colposcopic-suspicious-lesions
#9
J X Zhang, T P Zheng, J Liu, Q X Wang, Y X Zhan, Z Y Zhang
Objective: To explore the value of histopathologic diagnosis after colposcopy for high-risk HPV16/18 positive patients with negative cytology or atypical squamous cells of undetermined significance (ASCUS) for early screening of cervical lesions. Methods: A retrospective study of cervical histopathologic diagnosis in the HPV16/18 positive patients received colposcopy evaluation before got the histology was carried out between January 2014 and January 2016. The cytology of the patients should be negative or ASCUS...
July 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28796720/srs-22r-scores-in-nonoperated-adolescent-idiopathic-scoliosis-patients-with-curves-greater-than-forty-degrees
#10
W Timothy Ward, Nicole A Friel, Tanya S Kenkre, Maria M Brooks, Joanne A Londino, James W Roach
STUDY DESIGN: Case control comparative series. OBJECTIVE: Describe surgical range adolescent idiopathic scoliosis (AIS) patients electing to forgo surgery and compare health-related quality-of-life outcomes to a similar cohort of operated AIS patients by the same single surgeon. SUMMARY OF BACKGROUND DATA: No data have been published either documenting SRS-22r scores of nonoperated patients with curves ≥40° or comparing these scores to a demographically similar operated cohort...
August 15, 2017: Spine
https://www.readbyqxmd.com/read/28795156/results-of-ultrasound-assisted-brace-casting-for-adolescent-idiopathic-scoliosis
#11
Edmond H Lou, Doug L Hill, Andreas Donauer, Melissa Tilburn, Douglas Hedden, Marc Moreau
BACKGROUND: Four factors have been reported to affect brace treatment outcome: (1) growth or curve based risk, (2) the in-brace correction, (3) the brace wear quantity, and (4) the brace wear quality. The quality of brace design affects the in-brace correction and comfort which indirectly affects the brace wear quantity and quality. This paper reported the immediate benefits and results on using ultrasound (US) to aid orthotists to design braces for the treatment of scoliosis. METHODS: Thirty-four AIS subjects participated in this study with 17 (2 males, 15 females) in the control group and 17 (2 males, 15 females) in the intervention (US) group...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28793381/perceived-social-support-and-the-sense-of-coherence-in-patient-caregiver-dyad-versus-acceptance-of-illness-in-cancer-patients
#12
Małgorzata Pasek, Grażyna Dębska, Ewa Wojtyna
BACKGROUND: Acceptance of illness is a significant determinant of further coping with a disease. Development of illness acceptance may be associated with the sense of coherence and perception of social support. Cancer is an example of a crisis situation which affects both the patient and his/her close relatives. Consequently, acceptance of illness may be influenced by factors originating from both sides of caregiver-patient dyad. The aim of this study was to analyze direct and indirect interrelationships between perceived support and the sense of coherence (SOC) in patient-caregiver dyad, and acceptance of illness in cancer patients...
August 9, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28793241/the-activity-based-methodology-to-assess-ship-emissions-a-review
#13
REVIEW
R A O Nunes, M C M Alvim-Ferraz, F G Martins, S I V Sousa
Several studies tried to estimate atmospheric emissions with origin in the maritime sector, concluding that it contributed to the global anthropogenic emissions through the emission of pollutants that have a strong impact on hu' health and also on climate change. Thus, this paper aimed to review published studies since 2010 that used activity-based methodology to estimate ship emissions, to provide a summary of the available input data. After exclusions, 26 articles were analysed and the main information were scanned and registered, namely technical information about ships, ships activity and movement information, engines, fuels, load and emission factors...
August 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28792229/eugenol-exhibits-anti-virulence-properties-by-competitively-binding-to-quorum-sensing-receptors
#14
Prasanth Rathinam, H S Vijay Kumar, Pragasam Viswanathan
The primary objective of this study was to ascertain the anti-biofilm and anti-virulence properties of sub-minimum inhibitory concentration (MIC) levels of eugenol against the standard strain PAO1 and two multi-drug resistant P. aeruginosa clinical isolates utilizing quorum sensing inhibition (QSI). Eugenol at 400 μM significantly reduced biofilm formation on urinary catheters and the virulence factors (VF) including extracellular polysaccharides, rhamnolipid, elastase, protease, pyocyanin, and pyoverdine (p < 0...
August 9, 2017: Biofouling
https://www.readbyqxmd.com/read/28791548/insomnia-postpartum-depression-and-estradiol-in-women-after-delivery
#15
Ewa Drozdowicz-Jastrzębska, Michał Skalski, Paulina Gdańska, Anna Mach, Piotr Januszko, Rafał J Nowak, Piotr Węgrzyn, Mirosław Wielgoś, Maria Radziwoń-Zaleska
After childbirth, women may develop symptoms of depression with the associated sleep disturbances. This study assessed the relationship between insomnia and both depression symptoms and blood estradiol levels in women during the early postpartum period. 84 patients were assessed 24-48 h after labor. The main assessment methods were the following psychometric scales: Beck Depression Inventory (BDI), Edinburgh Postnatal Depression Scale (EPDS) and Athens Insomnia Scale (AIS). Serum estradiol levels were measured using ELISA assay...
August 8, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28790540/the-effect-of-adolescent-idiopathic-scoliosis-on-the-occurrence-of-varicose-veins-on-lower-extremities
#16
Goran Talic, Luka Talic, Djurdjica Stevanovic-Papica, Tatjana Nozica-Radulovic, Snjezana Novakovic-Bursac
INTRODUCTION: Scoliosis is a complex three-dimensional spine deformity with the frontal plane deflexion (side-shift) of the series of vertebra from the midline and with torque deformity of vertebra, ribs, and the entire trunk towards the apex of curve. Chronic venous diseases present a group of pathological conditions caused by the increased venous pressure. The venous pressure may be increased due to genetics, ligament laxity, general obesity, injuries, and changes in biomechanics of spine and lower extremities, etc...
April 2017: Medical Archives
https://www.readbyqxmd.com/read/28783210/monocyte-count-at-onset-predicts-post-stroke-outcomes-during-a-90-day-follow-up
#17
Luca Liberale, Fabrizio Montecucco, Aldo Bonaventura, Ilaria Casetta, Silva Seraceni, Alessandro Trentini, Marina Padroni, Franco Dallegri, Enrico Fainardi, Federico Carbone
BACKGROUND: Acute ischemic stroke (AIS) triggers both systemic and neurovascular inflammation, influencing post-stroke recovery. In smokers with AIS inflammation might be further upregulated, increasing ischemia/reperfusion injury. Here, the predictive value of leukocyte and adhesion molecules levels on post-stroke outcomes was investigated. MATERIALS AND METHODS: 89 patients with AIS (n=30 smokers and n=59 non-smokers) were recruited and evaluated 1, 7 and 90 days after the onset to assess stroke severity by the National Institute of Health Stroke Scale (NIHSS) score as well as clinical recovery at 90 day by the modified Rankin Scale (mRS)...
August 7, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28777353/a-dimensionality-reduction-based-multi-step-clustering-method-for-robust-vessel-trajectory-analysis
#18
Huanhuan Li, Jingxian Liu, Ryan Wen Liu, Naixue Xiong, Kefeng Wu, Tai-Hoon Kim
The Shipboard Automatic Identification System (AIS) is crucial for navigation safety and maritime surveillance, data mining and pattern analysis of AIS information have attracted considerable attention in terms of both basic research and practical applications. Clustering of spatio-temporal AIS trajectories can be used to identify abnormal patterns and mine customary route data for transportation safety. Thus, the capacities of navigation safety and maritime traffic monitoring could be enhanced correspondingly...
August 4, 2017: Sensors
https://www.readbyqxmd.com/read/28777161/lack-of-joint-hypermobility-increases-the-risk-of-surgery-in-adolescent-idiopathic-scoliosis
#19
Gabe Haller, Hannah Zabriskie, Shelby Spehar, Timothy Kuensting, Xavier Bledsoe, Ali Syed, Christina A Gurnett, Matthew B Dobbs
Generalized joint hypermobility (GJH) is a risk factor for developing adolescent idiopathic scoliosis (AIS); however, it is not known whether joint hypermobility influences the risk of progression to surgery. Beighton joint hypermobility scores were assessed in 570 female AIS patients. Multivariate analysis was carried out to determine whether Beighton hypermobility scores were predictors of surgical intervention. In this female AIS cohort, 24.7% (141/570) had GJH (Beighton score ≥4). Multivariate analysis showed that GJH did not influence the risk of surgery, although having no joint hypermobility (Beighton score=0) increased risk (odds ratio: 1...
August 2, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28776345/influence-of-daytime-or-nighttime-dosing-with-solifenacin-for-overactive-bladder-with-nocturia-impact-on-nocturia-and-sleep-quality
#20
Taekmin Kwon, Tae Hee Oh, Seong Choi, Won Yeol Cho, Kweonsik Min, Jeong Zoo Lee, Kyung Hyun Moon
We compared changes in nocturia and sleep-related parameters between daytime and nighttime solifenacin dosing in patents with overactive bladder (OAB) and nocturia. We comparatively analyzed the data of a 12-week prospective, open-label, multicenter, randomized study. All 127 patients who presented to 5 centers in Korea for the treatment of OAB with nocturia between January 2011 and December 2013 were enrolled in this study. The patients were divided into 2 groups by medication timing: group 1, daytime (n = 62); and group 2, nighttime (n = 65)...
September 2017: Journal of Korean Medical Science
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