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Pleural effusion

Joy C Edlin, Lorna Elizabeth Donovan, Clare Alexander, Robin Kanagasabay
We present the case of a 23-year-old woman with a long-standing history of recurrent left-sided pleural effusion unrelated to her menstrual cycle. At her last presentation, non-contrast-enhanced chest CT showed a pleural effusion and a lower left hemithorax mass, both large enough to cause complete collapse of the lower lobe and partial collapse of the upper lobe. Thoracoscopic surgery revealed a multilobulated mass originating from the dome of the diaphragm with pleural deposits. Histopathology diagnosed this as a calcifying fibrous tumour of the pleura, a rare benign tumour with excellent prognosis when completely excised...
September 15, 2018: BMJ Case Reports
Yun-Gyoo Lee, Ina Jung, Dong-Hoe Koo, Du-Young Kang, Tae Yoon Oh, Sukjoong Oh, Seung-Sei Lee
PURPOSE: Manifestations of malignant pleural effusions (MPEs) are alleviated by local therapies as well as by systemic treatment. After 2009, when commercial use of talc was discontinued in Korea, we have used Helixor-M, which is derived from the European mistletoe (Viscum album), as an alternative sclerosing agent for pleurodesis. We aimed to evaluate the efficacy and safety of Helixor-M for controlling MPE. METHODS: Between 2009 and 2015, we consecutively enrolled 52 patients with lung cancer, who underwent pleurodesis to treat MPE and were analyzed retrospectively...
September 14, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Junyun He, Rui Zhang, Yongchun Shen, Chun Wan, Ni Zeng, Jiangyue Qin, Panwen Tian, Lei Chen
OBJECTIVE: Reliable markers for accurately diagnosing tuberculous pleural effusions (TPE) are needed. This study sought to investigate the diagnostic potential of pleural interleukin-22 (IL-22) and compare it with the performance of adenosine deaminase (ADA). METHOD: This prospective study involved 49 patients with TPE and 60 patients with pleural effusion of other causes. Pleural levels of IL-22 and ADA were determined, respectively, using ELISA or an enzymatic method...
September 11, 2018: Current Research in Translational Medicine
Hsi-Yu Yu, Hsiao-En Tsai, Nai-Hsin Chi, Kuan-Ting Kuo, Shoei-Shen Wang, Chi-An Chen, Yih-Sharng Chen
BACKGROUND: Intravascular leiomyomatosis (IVL) is relatively rare. The optimal surgical method and long-term outcomes are not completely understood. METHODS: Medical records between 2007 and 2017 in our hospital were analyzed to identify IVL cases with surgical intervention. Their medical records, operative details, and follow-up were collected by chart review and telephone communication. RESULTS: Eight patients with IVL were included in the study, accounting for 0...
September 11, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Jessica L Ward, Gregory R Lisciandro, Wendy A Ware, Austin K Viall, Brent D Aona, Kari A Kurtz, Yamir Reina-Doreste, Teresa C DeFrancesco
BACKGROUND: The diagnosis of congestive heart failure (CHF) in cats is challenging. Point-of-care (POC) thoracic ultrasound and NT-proBNP testing are emerging tools that may aid in diagnosis. HYPOTHESIS/OBJECTIVES: To assess the diagnostic accuracy of POC lung ultrasound (LUS), focused cardiac ultrasound (FCU), and NT-proBNP in predicting a final diagnosis of CHF. ANIMALS: Fifty-one cats in respiratory distress. METHODS: Blood NT-proBNP, LUS, and FCU evaluating left atrial (LA) size and presence of pericardial effusion (PCEFF) were performed in all cats...
September 14, 2018: Journal of Veterinary Internal Medicine
Coenraad F N Koegelenberg, Brian W Allwood
No abstract text is available yet for this article.
September 13, 2018: Respiration; International Review of Thoracic Diseases
Du Kong, Wei Wang, Gang Du, Binyao Shi, Zhengchen Jiang, Bin Jin
Background: Although liver retraction using n-butyl-2-cyanoacrylate (NBCA) glue has been applied to laparoscopic upper abdominal surgery in noncirrhotic patients, there is still no consensus on its safety and feasibility for cirrhotic patients. In this study, we aimed to investigate the safety and effectiveness of liver retraction using NBCA glue during laparoscopic splenectomy and azygoportal disconnection (LSD) for gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension...
2018: BioMed Research International
Muhammad Shabbir Rawala, Muhammad Farhan Khaliq, Muhammad Asif Iqbal, S Tahira Shah Naqvi, Kinaan Farhan, Andrew Myers, Kristen Helmick
Endometriosis is a common condition in which endometrial cells and stroma are deposited in extrauterine sites. Its prevalence has been estimated to be 10% of reproductive age females. It is commonly found in the pelvis; however, it may be found in the abdomen, thorax, brain, or skin. Thoracic involvement is a relatively rare presentation of this common disease. Thoracic endometriosis commonly presents as pneumothorax in 73% of patients. A rarer presentation of thoracic endometriosis is hemothorax (<14%) or hemoptysis (7%)...
2018: Case Reports in Pulmonology
Ali Kord Valeshabad, Jennifer Acostamadiedo, Lekui Xiao, Winnie Mar, Karen L Xie
A 49-year-old male with history of chronic alcohol-induced pancreatitis presented with one month of worsening left pleuritic chest pain and shortness of breath. Chest radiograph demonstrated bilateral pleural effusions. Thoracentesis revealed increased amylase in the pleural fluid. Computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP) showed a fistula tract between the left pleural cavity and pancreas which was confirmed on endoscopic retrograde cholangiopancreatography (ERCP). Patient was treated with placement of a pancreatic stent with complete resolution of the fistula tract approximately in 9 weeks...
2018: Case Reports in Gastrointestinal Medicine
Kowthar S Hassan, Ghalib Al-Khadouri
Mycoplasma pneumoniae is a common cause of community-acquired pneumonia. As M. pneumoniae pneumonia is usually a mild and self-limiting disease, complications such as pleural effusion occur only rarely. We report a 22-year-old woman who presented to the Emergency Medicine Department of the Sultan Qaboos University Hospital, Muscat, Oman, in 2017 with an eight-day history of fever associated with coughing, chills and rigors. She was diagnosed with M. pneumoniae pneumonia, but subsequently developed pleural effusion which worsened despite treatment with appropriate antimicrobials...
May 2018: Sultan Qaboos University Medical Journal
Igor Kocijancic, Jernej Vidmar, Marko Kastelic
Background Pleural effusion remains largely unexplored in patients with pulmonary embolism and concurrent pulmonary infarction. The aim of the study was to investigate the relationship between the size of pulmonary infarction and pleural effusion as well as the time course of pleural effusion in patients with pulmonary infarction. Patients and methods Data from 103 patients with pulmonary infarction was retrospectively analysed along with patient comorbidities, size of pulmonary infarction, presence and size of pleural effusion with the time between the onset of clinical symptoms of pulmonary infarction and CT study...
September 11, 2018: Radiology and Oncology
Steven Grocholski, Shantanu Banerji, Gefei Qing, David E Dawe
Crizotinib is a first line treatment for patients with non-small cell lung cancer (NSCLC) harboring translocations in anaplastic lymphoma kinase (ALK). The current gold standard for determining ALK status is fluorescence in-situ hybridisation (FISH), but immunohistochemistry (IHC) is becoming increasingly popular due to lower cost. There are currently few reports on clinical outcomes with crizotinib therapy in patients who have tested negative by FISH and positive by IHC. A 53 year old lifelong non-smoking, physically active male with newly diagnosed Stage IV NSCLC presented with shortness of breath on exertion one month prior to referral...
2018: Cancer Treatment and Research Communications
Jia-Feng Chang, Shih-Shin Liang, Pounraj Thanasekaran, Hsueh-Wei Chang, Li-Li Wen, Chung-Hua Chen, Jian-Chiun Liou, Jih-Chen Yeh, Shih-Hao Liu, Huei-Min Dai, Wei-Ning Lin
Molecular mechanisms and pathological features of p-Cresyl sulfate (PCS)-induced uremic lung injury (ULI) in chronic kidney disease (CKD) remain unclear. We analyzed pleural effusions (PE) from CKD and non-CKD patients for uremic toxins, reactive oxygen species (ROS), and chemotactic cytokines. Correlations between PE biomarkers and serum creatinine were also studied. Cell viability and inflammatory signaling pathways were investigated in PCS-treated human alveolar cell model. To mimic human diseases, CKD-ULI mouse model was developed with quantitative comparison of immunostaining and morphometric approach...
September 9, 2018: Journal of Clinical Medicine
Michael A Mitchell, Andrew Burkett, Pen Li, Tinghua Zhang, Kayvan Amjadi
BACKGROUND: Indwelling pleural catheters (IPC) are commonly used in the management of malignant pleural effusions (MPE). The effect of systemic chemotherapy on IPC removal has not been reported previously. OBJECTIVES: The purpose of this study is to identify the effect of chemotherapy on the removal of IPCs in breast cancer patients with MPEs. METHODS: In this retrospective cohort study at an academic tertiary-care center, patients with breast cancer and MPE who received an IPC between 2006 and 2016 were identified from a prospectively collected database...
September 11, 2018: Respiration; International Review of Thoracic Diseases
Duneesha de Fonseka, Rahul Bhatnagar, Nick A Maskell
BACKGROUND: Local anaesthetic thoracoscopy (LAT) is an important procedure in the management pathway of patients with pleural effusions, particularly those with suspected malignancy. The last survey evaluating the use and development of LAT services in the UK was conducted over a decade ago. OBJECTIVES: We performed a survey of LAT practices in the UK to explore procedural preferences and variations in practice. METHODS: The online survey was cascaded via regional pleural specialists to sites performing LAT...
September 10, 2018: Respiration; International Review of Thoracic Diseases
Gulsum Iclal Bayhan, Fuat Sayir, Gonul Tanir, Oguz Tuncer
Background: Pleural tuberculosis (TB) diagnosis is sometimes controversial because the microbiologic confirmation ratio is very low in pleural fluid. There are few pediatric pleural TB case series in the literature. Methods: We retrospectively evaluated our TB cases below 18 years of age and extracted pleural TB cases. Results: Seven cases with pleural TB were identified. About 42.9% of the patients had isolated pleural TB whereas 57.1% of the patients had accompanying pulmonary TB...
July 2018: International Journal of Mycobacteriology
Jian Min Ooi, Kah Peng Eg, Karuthan Chinna, Anna M Nathan, Jessie A de Bruyne, Surendran Thavagnanam
AIM: To investigate baseline characteristics associated with complicated community-acquired pneumonia (CAPc) in Malaysian children. CAPc, such as pleural effusion and/or empyema, is on the rise, especially in Southeast Asian children, and the reasons for this are unknown. METHODS: A retrospective study was conducted on all children aged 2-16 years who were admitted to the University Malaya Medical Centre with community-acquired pneumonia between 2012 and 2014...
September 9, 2018: Journal of Paediatrics and Child Health
Mirko Zanatta, Piero Benato, Sigilfredo De Battisti, Concetta Pirozzi, Renato Ippolito, Vito Cianci
BACKGROUND: Pre-hospital ultrasound is a new challenge and lung ultrasound could be an interesting opportunity in the pre-hospital medical service. The aim of our study was to evaluate the efficacy of lung ultrasound in out-of-hospital non-traumatic respiratory insufficiency. METHODS: We planned a case-controlled study in the ULSS 5 ovest vicentino area (Vicenza-Italy) enrolling subjects with severe dyspnea caused by cardiac heart failure or acute exacerbation of chronic obstructive pulmonary disease...
September 10, 2018: Critical Ultrasound Journal
Akinori Watanabe, Chikatoshi Katada, Shouko Komori, Hiromitsu Moriya, Keishi Yamashita, Hiroki Harada, Mizutomo Azuma, Yuki Kondo, Yo Kubota, Yasuaki Furue, Natsuko Kawanishi, Sakiko Yamane, Takuya Wada, Takafumi Yano, Kenji Ishido, Satoshi Tanabe, Kazushige Hayakawa, Wasaburo Koizumi
Purpose: This study was designed to retrospectively analyze the safety and efficacy of chemoradiation therapy with nedaplatin and 5-fluorouracil in elderly patients with esophageal squamous cell carcinoma. Methods and materials: Eligible patients were aged 76 years or older, had a histopathologic diagnosis of esophageal squamous cell carcinoma, and were treated at the Kitasato University Hospital between January 2010 and March 2016. Chemotherapy consisted of nedaplatin in an intravenous dose of 90 mg/m2 on day 1 and 5-fluorouracil in an intravenous dose of 800 mg/m2 on days 1 to 5, repeated every 4 weeks for 2 cycles...
July 2018: Advances in Radiation Oncology
Michiyuki Hakozaki, Hirosumi Tamura, Yuu Dobashi, Aki Yoshida, Kouki Kato, Takahiro Tajino, Hitoshi Yamada, Yoichi Kaneuchi, Kiyoaki Katahira, Junji Ezaki, Satoshi Waguri, Shinichi Konno, Shinya Watanabe
BACKGROUND/AIM: Clear cell sarcoma (CCS) of soft tissue is exceedingly rare and frequently exhibits aggressive behavior. Toward the goals of improving the aggressive course and poor prognosis of CCS, and establish new therapeutic methods, molecular genetic and biological characterizations of CCS are required. MATERIALS AND METHODS: A new human CCS cell line (designated RSAR001) was established from the pleural effusion of a 44-year-old man with multiple lung metastases and pleural dissemination...
September 2018: Anticancer Research
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