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Pleural effusion

Ruth Sobala, Kevin Conroy, Hilary Tedd, Salem Elarbi
Can you diagnose this eosinophilic patient with a pleural effusion?
December 2017: Breathe
Naoto Ishimaru, Hisashi Ohnishi, Mao Fujii, Masako Yumura, Sho Yoshimura, Saori Kinami
We describe a case of microscopic polyangiitis manifested as pleuritis confirmed by thoracoscopic biopsy. An 80-year-old man presented with a three-day history of shortness of breath and cough. Chest radiography revealed patchy opacities in the lower fields of the bilateral lung and right-sided pleural effusion. Thoracentesis revealed lymphocytic pleural exudates. Thoracoscopic biopsy specimens were compatible with fibrotic pleuritis. He developed rapidly progressive glomerulonephritis with elevated myeloperoxidase anti-neutrophil cytoplasmic antibody titer in blood and pleural effusion...
June 21, 2018: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
M Schirren, S Sponholz, J Schirren
Chylothorax is an infrequent but important form of pleural effusion. The most common causes are of postoperative and neoplastic origin. No prospective or randomized trials have been performed to evaluate the available treatment options for chylothorax. The basic principles of conservative treatment include drainage of the effusion and dietary measures. Chylothorax is typically treated conservatively. In the case of failure of conservative treatment, interventional radiological or surgical procedures are applied...
June 20, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Arunkumar Subbiah, Sandeep Mahajan, Raj Kanwar Yadav, Sanjay Kumar Agarwal
A 45-year-old man presented 4 months after ABOi renal transplantation with febrile illness and bicytopenia necessitating cessation of mycophenolate mofetil. Dengue non-structural protein 1 antigen (NS1 Ag) test was positive. Lowest total leucocyte count was 3.1×109 /L and platelet count was 14×109 /L. As fever subsided, patient became tachypneic with abdominal distention and hypotension. Ultrasonographic evaluation revealed ascites, gall bladder wall oedema and bilateral pleural effusion consistent with dengue capillary leak syndrome...
June 19, 2018: BMJ Case Reports
Lisheng Xu, Benjie Wang, Meimei Gao, Yan Zhang, Qian Qi, Tao Li, Caiyu Li, Aihua Wang, Yu Li
BACKGROUND: Malignant pleural effusion is a common complication of non-small cell lung cancer (NSCLC); however, treatment options remain limited. This study evaluated the safety and efficacy of sequential intrapleural therapy with lobaplatin and erythromycin for NSCLC-mediated malignant pleural effusion. METHODS: Fifty-six patients with NSCLC complicated with malignant pleural effusion were recruited for a prospective single-arm study from December 2014 to 2016; one patient dropped out...
June 19, 2018: Thoracic Cancer
Juan José Arenas-Jiménez, Elena García-Garrigós, Carmen Escudero-Fresneda, Marina Sirera-Matilla, Irene García-Pastor, Alberto Quirce-Vázquez, Mariana Planells-Alduvin
OBJECTIVE: To compare images from early and delayed phases of contrast-enhanced thoracic CT for assessing pleural thickening or nodules in a series of patients with malignant pleural effusions. METHODS: Blinded images from 36 patients with malignant pleural effusions showing pleural lesions in both early (35 s delayed) and delayed (70 s delayed) phases of thoracic and abdominal contrast-enhanced CT scan were retrospectively assessed by six observers. First, images were individually scored in a six-point scale grading the quality of visualization of pleural findings such as pleural thickening or nodules...
June 19, 2018: British Journal of Radiology
Surinder Singh Rana, Ravi Sharma, Rajesh Gupta
BACKGROUND: Pleural effusion is a common finding both in patients with benign and malignant diseases of pleura and lung with diagnostic thoracentesis establishing the diagnosis in the majority of cases. The diagnostic thoracentesis can be done either blindly or under the guidance of ultrasound or computed tomography. However, minimal pleural effusion is difficult to sample even under image guidance. Endoscopic ultrasound (EUS) is known to detect smaller volume of pleural effusion and, thus, can help in guiding thoracentesis...
June 19, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Catarina Silva-Costa, Maria João Brito, Marcos D Pinho, Ana Friães, Sandra I Aguiar, M Ramirez, Jose Melo-Cristino
Despite use of 7-valent pneumococcal conjugate vaccine, incidence of pleural effusion and empyema (pediatric complicated pneumococcal pneumonia [PCPP]) is reportedly increasing globally. We cultured and performed PCR on 152 pleural fluid samples recovered from pediatric patients in Portugal during 2010-2015 to identify and serotype Streptococcus pneumoniae. We identified only 17 cases by culture, but molecular methods identified S. pneumoniae in 68% (92/135) of culture-negative samples. The most frequent serotypes were 3, 1, and 19A, together accounting for 62% (68/109) of cases...
July 2018: Emerging Infectious Diseases
Ioannis Psallidas, Nikolaos I Kanellakis, Stephen Gerry, Marie Laëtitia Thézénas, Philip D Charles, Anastasia Samsonova, Herbert B Schiller, Roman Fischer, Rachelle Asciak, Robert J Hallifax, Rachel Mercer, Melissa Dobson, Tao Dong, Ian D Pavord, Gary S Collins, Benedikt M Kessler, Harvey I Pass, Nick Maskell, Georgios T Stathopoulos, Najib M Rahman
BACKGROUND: The prevalence of malignant pleural effusion is increasing worldwide, but prognostic biomarkers to plan treatment and to understand the underlying mechanisms of disease progression remain unidentified. The PROMISE study was designed with the objectives to discover, validate, and prospectively assess biomarkers of survival and pleurodesis response in malignant pleural effusion and build a score that predicts survival. METHODS: In this multicohort study, we used five separate and independent datasets from randomised controlled trials to investigate potential biomarkers of survival and pleurodesis...
June 13, 2018: Lancet Oncology
Paul Baas, Sjaak Burgers
No abstract text is available yet for this article.
June 13, 2018: Lancet Oncology
Diane Frankel, Andrée Robaglia-Schlupp, Donatienne Bourlard, Elise Kaspi, Patrice Roll
Quiz related to cytological examination of pleural effusion in a patient with history of latero-thoracic malignant melanoma. This article is protected by copyright. All rights reserved.
June 16, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
Yoav Bichovsky, Leonid Koyfman, Michael Friger, Boris Kirshtein, Abraham Borer, Gilbert Sebbag, Dmitry Frank, Amit Frenkel, Jochanan G Peiser, Moti Klein, Evgeni Brotfain
PURPOSE: Peritonitis is a major complication of bariatric surgery due to direct damage to the natural barriers to infection. Most such secondary peritoneal infections are caused by Gram-negative microorganisms; however, under certain conditions, Candida species can infect the peritoneal cavity following bariatric surgery. MATERIALS AND METHODS: We retrospectively analyzed the clinical and microbiological data of morbidly obese patients who suffered infectious complications following laparoscopic sleeve gastrectomy (LSG) at the Soroka Medical Center between January 2010 and June 2015...
June 15, 2018: Obesity Surgery
Peter Sawan, Andrew J Plodkowski, Angela E Li, Bob T Li, Alexander Drilon, Marinela Capanu, Michelle S Ginsberg
OBJECTIVES: To describe the radiological phenotype of HER2-mutant lung cancers on CT at presentation. METHODS: Eligible patients with lung adenocarcinomas with HER2 mutations were stage-matched with two control groups (EGFR- and KRAS-mutant groups). Evaluated CT features of the primary tumor included size, location, consistency, contour, presence of pleural tags and pleural retractions. Presence of pleural effusions, lung metastases, adenopathy, chest wall invasion, and were also recorded...
June 7, 2018: Clinical Imaging
Parikshaa Gupta, Nalini Gupta, Amanjit Bal, Inderpaul Singh Sehgal, Valliappan Muthu, Arvind Rajwanshi
Thoracic endometriosis is the presence of endometrial tissue in the pleura, lung parenchyma and/or airways. It is an extremely rare occurence and is challenging to diagnose clinically due to variable clinical presentations. A high index of clinical suspicion and recognition of the association of the clinical symptoms with menstruation is important to establish a clinical diagnosis of pleural endometriosis. The definitive diagnosis requires tissue diagnosis, demonstrating the presence of endometrial tissue in pleura, either by cytological or histopathological examination...
June 14, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
Partha Hota, Chandra Dass, Maruti Kumaran, Xiaofeng Zhao, Nirag Jhala, Scott Simpson
Although the lung is a common site for metastatic disease from extrathoracic malignancies, a pattern of lepidic growth of these metastases is considered rare. A 67-year-old man with a history of partial hepatectomy for hepatocellular carcinoma (HCC) presented to our hospital with dyspnea and a nonproductive cough. Chest radiographs and computed tomography imaging demonstrated consolidation in the right upper lobe and an ipsilateral pleural effusion. Findings were initially suspected to be secondary to infection, given the radiographic appearance and the rapid development from a normal computed tomography 3 months previously...
April 2018: Radiology Case Reports
Qiuping Xu, Jie Shao, Shu Su, Jia Wei, Fangjun Chen, Fanyan Meng, Yang Zhao, Juan Du, Zhengyun Zou, Xiaoping Qian, Baorui Liu
Adoptive cell therapy (ACT) of autologous tumor-infiltrating lymphocytes (TILs) has shown an effect on mediating tumor regression in some patients with highly advanced, refractory metastatic malignancy. Here, the in vitro generation of TILs isolated from malignant pleural effusion and ascites was compared with which using engineered cells for costimulatory enhancement (ECCE) and 3 common γ-chain cytokines, interleukin (IL)-2, IL-7, and IL-15, alone or in combination. We showed the robust clinical-scale production of TILs with a less differentiated 'young' phenotype by expansion in the presence of ECCE combined with IL-2/7/15...
April 17, 2018: Cellular Immunology
So-Hyun Nam, Kyoung-Ah Kwon
BACKGROUND: Lymphatic malformations are histologically benign vascular structures that vary in anatomic lesion and size. Extensive head and neck lymphatic malformations may be life-threatening. In the present study, we described three difficult-to-treat infants with giant cervico-mediastinal lymphatic malformations accompanied by severe respiratory distress. CASE PRESENTATIONS: Case 1. A Korean girl born at a gestational age of 37 weeks and weighing 2920 g had a large cervical mass compressing the trachea...
June 15, 2018: Journal of Medical Case Reports
Suresh Giritharan, Kareem Salhiyyah, Geoffrey M Tsang, Sunil K Ohri
BACKGROUD: To assess the feasibility and efficacy of PuraStat®, a novel haemostatic agent, in achieving suture line haemostasis in a wide range of cardiac surgical procedures and surgery of the thoracic aorta. METHODS: A prospective, non-randomised study was conducted at our institution. Operative data on fifty consecutive patients undergoing cardiac surgery where PuraStat® was utilised in cases of intraoperative suture line bleeding was prospectively collected...
June 15, 2018: Journal of Cardiothoracic Surgery
Rajan Atwal, Charles Stewart
We describe the unique case of a child with pneumonia presenting with acute scoliosis and abdominal pain, without any typical features of the disease.A 10-year-old girl presented to the emergency department on 3 consecutive days with right-sided abdominal pain. There were no associated features, in particular, no fevers or respiratory symptoms. On the first 2 presentations, observation,examination, and blood test findings were unremarkable. Chest x-ray and abdominal ultrasound were also normal. On the third presentation a marked scoliosis was noted and abdominal examination revealed right-sided tenderness with rebound...
June 2018: Medicine (Baltimore)
Andrea M Walters, Mauria A O'Brien, Laura E Selmic, Sue Hartman, Maureen McMichael, Robert T O'Brien
OBJECTIVE: To determine the agreement between focused assessment with sonography for trauma (FAST) exams and computed tomography (CT) for the detection of pleural and peritoneal fluid and pneumothorax in animals that have sustained recent trauma. DESIGN: Prospective study. SETTING: University Teaching Hospital. ANIMALS: Thirteen dogs and 2 cats were enrolled into the study, with 10 having sustained blunt force trauma and 5 penetrating trauma...
June 14, 2018: Journal of Veterinary Emergency and Critical Care
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