keyword
MENU ▼
Read by QxMD icon Read
search

Osteochondritis

keyword
https://www.readbyqxmd.com/read/28437619/management-of-posterior-cruciate-ligament-tibial-avulsion-injuries-a-systematic-review
#1
Perry O Hooper, Chris Silko, Tennison L Malcolm, Lutul D Farrow
BACKGROUND: Tibial-sided avulsion injuries of the posterior cruciate ligament (PCL) generally require surgical intervention. No consensus exists concerning the optimal surgical treatment approach for these injuries. PURPOSE: To perform a systematic review investigating the open and arthroscopic surgical treatment modalities, outcomes, and complications of PCL tibial-sided bony avulsions. STUDY DESIGN: Systematic review; Level of evidence, 4...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28429865/differential-effects-of-bleeds-on-the-development-of-arthropathy-basic-and-applied-issues
#2
REVIEW
L F D van Vulpen, S C Mastbergen, F P J G Lafeber, R E G Schutgens
Haemophilia is characterized by a spontaneous bleeding tendency, affecting mainly the synovial joints. Recurrent joint bleeds induce a cascade of inflammatory as well as degenerative processes injuring synovium, cartilage and bone. These processes affect each other and may occur in parallel and/or sequentially. Clinically, the effects of joint bleeds are heterogeneous. A marked variability in joint damage is observed in patients with a similar bleeding history. Also late stage effects differ with some patients developing chronic synovitis, and others suffering from osteochondral degeneration called haemophilic arthropathy...
April 21, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28419816/high-rate-of-osteoarthritis-after-osteochondritis-dissecans-fragment-excision-compared-with-surgical-restoration-at-a-mean-16-year-follow-up
#3
Thomas L Sanders, Ayoosh Pareek, Mitchel R Obey, Nicholas R Johnson, James L Carey, Michael J Stuart, Aaron J Krych
BACKGROUND: Osteochondritis dissecans (OCD) is a disorder of subchondral bone that causes adverse effects on the overlying cartilage and commonly affects the knee. The incidence of OCD and its long-term effect on the knee joint are controversial. Hypothesis/Purpose: The purpose of this study was to (1) evaluate the rate of osteoarthritis and knee arthroplasty in a population-based cohort of patients with OCD lesions treated operatively and (2) evaluate factors that may predispose patients to knee osteoarthritis and arthroplasty...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28419612/delayed-gadolinium-enhanced-mri-of-cartilage-dgemric-and-t2-mapping-of-talar-osteochondral-lesions-indicators-of-clinical-outcomes
#4
Christoph Rehnitz, Benita Kuni, Felix Wuennemann, Dimitrios Chloridis, Anand Kirwadi, Iris Burkholder, Hans-Ulrich Kauczor, Marc-André Weber
PURPOSE: To evaluate the utility of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) and T2 mapping in evaluation of type II osteochondral lesions (OCLs) of the talus and define cutoff values for identifying patients with good/poor clinical outcomes. MATERIALS AND METHODS: 28 patients (mean age, 42.3 years) underwent T2 mapping and dGEMRIC at least 1.5 years (mean duration, 3.5 years) after microfracture (n = 12) or conservative (n = 16) treatment for type II OCL...
April 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28418278/the-effect-of-surgical-insertion-and-proinflammatory-cytokines-on-osteochondral-allograft-survival-and-metabolism
#5
Samantha L Gitelis, Ariel Bodker, Michel P Laurent, Spencer S Kirk, Giuseppe Filardo, Maximilian A Meyer, Arnavaz A Hakimiyan, Lev Rappoport, Markus A Wimmer, Brian J Cole, Susan Chubinskaya
Objective To investigate the responses of refrigerated osteochondral allograft cartilage (OCA) and fresh cartilage (FC), including cell survival and metabolism, to surgical impaction and proinflammatory cytokines. Design Osteochondral plugs (8 mm diameter) were harvested from prolonged-refrigerated (14-28 days) and fresh (≤24 hours postmortem) human femoral hemicondyles and subjected to a 0.2 N s pneumatic impaction impulse. Cartilage explants were removed from subchondral bone and randomized to 1 of 6 treatment groups: (1) Unimpacted control (UIC), (2) Impacted control (IC), (3) Impacted + interleukin (IL)-1β (0...
January 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28413129/return-to-play-after-osteochondral-autograft-transplantation-of-the-capitellum-a-systematic-review
#6
REVIEW
Jacob M Kirsch, Jared R Thomas, Moin Khan, Whitney A Townsend, Jeffrey N Lawton, Asheesh Bedi
PURPOSE: To determine the rate of return to play and to identify lesion or osteochondral graft characteristics that may influence the return to competitive athletics after osteochondral autograft transplantation (OAT) for symptomatic osteochondritis dissecans (OCD) lesions. METHODS: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A duplicate search of PubMed, Embase, Scopus, Web of Science, and CENTRAL databases was performed, beginning from the database inception dates through July 2016, for all articles evaluating the return to play after OAT for OCD lesions of the capitellum...
April 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28411451/anisotropic-tough-double-network-hydrogel-from-fish-collagen-and-its-spontaneous-in%C3%A2-vivo-bonding-to-bone
#7
Md Tariful Islam Mredha, Nobuto Kitamura, Takayuki Nonoyama, Susumu Wada, Keiko Goto, Xi Zhang, Tasuku Nakajima, Takayuki Kurokawa, Yasuaki Takagi, Kazunori Yasuda, Jian Ping Gong
Soft supporting tissues in the human body, such as cartilages and ligaments, are tough materials and firmly fixed to bones. These soft tissues, once injured, cannot regenerate spontaneously in vivo. Developing tough and biocompatible hydrogels as artificial soft supporting tissues would substantially improve outcomes after soft tissue injury. Collagen is the main rigid component in soft connective tissues which is organized in various hierarchical arrays. We have successfully developed a novel class of collagen fibril-based tough hydrogels based on the double network (DN) concept using swim bladder collagen (SBC) extracted from Bester sturgeon fish...
July 2017: Biomaterials
https://www.readbyqxmd.com/read/28409110/anatomic-humeral-head-reconstruction-with-fresh-osteochondral-talus-allograft-for-recurrent-glenohumeral-instability-with-reverse-hill-sachs-lesion
#8
Matthew T Provencher, George Sanchez, Katrina Schantz, Marcio Ferrari, Anthony Sanchez, Salvatore Frangiamore, Sandeep Mannava
The treatment of recurrent glenohumeral instability, especially with a concomitant bony lesion, remains challenging. This is especially true in the case of posterior instability given its less common incidence. Moreover, the presence of an engaging reverse Hill-Sachs lesion in combination with posterior instability will result in the need for a more aggressive treatment option. In comparison with a Hill-Sachs lesion, a reverse Hill-Sachs lesion features greater chondral deficiency that must be addressed during treatment...
February 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28409096/ankle-arthroscopy-with-microfracture-for-osteochondral-defects-of-the-talus
#9
Suman Medda, Ian M Al'Khafaji, Aaron T Scott
Therapeutic arthroscopy with microfracture leads to fibrocartilaginous repair and is an effective treatment of osteochondral lesions of the talus. A full diagnostic arthroscopy is performed, and then attention is turned to the osteochondral defect. We describe in detail patient positioning, ankle distraction, portal placement, steps of the diagnostic arthroscopy, and the technique of microfracture. We then discuss the special considerations to be taken regarding the use of a distractor, protection of neurovascular structures, and the indications for microfracture...
February 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28406879/physical-examination-of-the-knee-meniscus-cartilage-and-patellofemoral-conditions
#10
Robert D Bronstein, Joseph C Schaffer
The knee is one of the most commonly injured joints in the body. Its superficial anatomy enables diagnosis of the injury through a thorough history and physical examination. Examination techniques for the knee described decades ago are still useful, as are more recently developed tests. Proper use of these techniques requires understanding of the anatomy and biomechanical principles of the knee as well as the pathophysiology of the injuries, including tears to the menisci and extensor mechanism, patellofemoral conditions, and osteochondritis dissecans...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28406876/cartilage-restoration-techniques-for-the-patellofemoral-joint
#11
Robert H Brophy, Robert D Wojahn, Joseph D Lamplot
Symptomatic osteochondral lesions of the patellofemoral joint are clinically challenging to manage because of the limited healing potential of articular cartilage; the complex morphology of the patellofemoral joint; the heterogeneity of the articular surface between patients; and high stresses across the joint, which can be altered by malalignment, tilt, or maltracking. Indications for surgery include traumatic lesions, osteochondritis dissecans, and high-grade chondromalacia in association with persistent pain despite a course of nonsurgical management...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28401793/developing-a-customized-perfusion-bioreactor-prototype-with-controlled-positional-variability-in-oxygen-partial-pressure-for-bone-and-cartilage-tissue-engineering
#12
Poh Soo Lee, Hagen Eckert, Ricarda Hess, Michael Gelinsky, Derrick Rancourt, Roman Krawetz, Gianaurelio Cuniberti, Dieter Scharnweber
Skeletal development is a multi-step process that involves the complex interplay of multiple cell types at different stages of development. Besides biochemical and physical cues, oxygen tension also plays a pivotal role in influencing cell fate during skeletal development. At physiological conditions, bone cells generally reside in relatively oxygenated environment whereas the chondrocytes reside in hypoxic environment. However, it is technically challenging to achieve such defined, yet diverse oxygen distribution on traditional in vitro cultivation platforms...
April 12, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28401159/management-of-hepple-stage-v-osteochondral-lesion-of-the-talus-with-a-platelet-rich-plasma-scaffold
#13
Wenqi Gu, Tanzhu Li, Zhongmin Shi, Guohua Mei, Jianfeng Xue, Jian Zou, Xiaokang Wang, Haotong Zhang, Hongwei Xu
There has been no consensus on the treatment or prognosis of Hepple stage V osteochondral lesions of the talus (OLTs), especially for lesions greater than 1.5 cm(2) in size. The objective of this study was to investigate the clinical outcomes achieved upon application of a platelet-rich plasma (PRP) scaffold with a cancellous bone autograft for Hepple stage V OLTs. Fourteen patients (mean age, 39 years) were treated with a cancellous bone graft and a PRP scaffold between 2013 and 2015. The mean time to surgical treatment was 23...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28399642/acute-tears-of-the-tibialis-posterior-tendon-following-ankle-sprain
#14
Lyle T Jackson, Linda J Dunaway, Gregory A Lundeen
BACKGROUND: Traumatic tears of the tibialis posterior (TP) tendon following an ankle sprain are rare. The purpose of this study was to report our case series of TP tendon tears following an ankle sprain. METHODS: Patients with persistent TP tendon pain after an ankle sprain were retrospectively identified over a 4-year period and reviewed. A comparison of magnetic resonance imaging (MRI) interpretations by a radiologist and surgeon was made. Patients failing conservative management underwent operative repair of the TP tendon tear and concomitant pathology...
April 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28399641/optimization-of-degradation-profile-for-new-scaffold-in-cartilage-repair
#15
Sarav S Shah, Haixiang Liang, Sandeep Pandit, Zalak Parikh, John A Schwartz, Todd Goldstein, Lawrence P Lavelle, Arindam Datta, Daniel A Grande
Objective To establish whether a novel biomaterial scaffold with tunable degradation profile will aid in cartilage repair of chondral defects versus microfracture alone in vitro and in a rat model in vivo. Design In vitro-Short- and long-term degradation scaffolds were seeded with culture expanded articular chondrocytes or bone marrow mesenchymal stem cells. Cell growth and differentiation were evaluated with cell morphological studies and gene expression studies. In vivo-A microfracture rat model was used in this study to evaluate the repair of cartilage and subchondral bone with the contralateral knee serving as the empty control...
April 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28398084/the-reliability-of-assessing-radiographic-healing-of-osteochondritis-dissecans-of-the-knee
#16
Eric J Wall, Matthew D Milewski, James L Carey, Kevin G Shea, Theodore J Ganley, John D Polousky, Nathan L Grimm, Emily A Eismann, Jake C Jacobs, Lucas Murnaghan, Carl W Nissen, Gregory D Myer, Jennifer Weiss, Eric W Edmonds, Allen F Anderson, Roger M Lyon, Benton E Heyworth, Peter D Fabricant, Andy Zbojniewicz
BACKGROUND: The reliability of assessing healing on plain radiographs has not been well-established for knee osteochondritis dissecans (OCD). PURPOSE: To determine the inter- and intrarater reliability of specific radiographic criteria in judging healing of femoral condyle OCD. STUDY DESIGN: Cohort study (Diagnosis); Level of evidence, 3. METHODS: Ten orthopedic sports surgeons rated the radiographic healing of 30 knee OCD lesions at 2 time points, a minimum of 1 month apart...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28396070/novel-pathogenic-acan-variants-in-non-syndromic-short-stature-patients
#17
Xuyun Hu, Baoheng Gui, Jiasun Su, Hongdou Li, Niu Li, Tingting Yu, Qinle Zhang, Yufei Xu, Guoqiang Li, Yulin Chen, Yanrong Qing, Chuan Li, Jingsi Luo, Xin Fan, Yu Ding, Juan Li, Jian Wang, Xiumin Wang, Shaoke Chen, Yiping Shen
BACKGROUND: Pathogenic variants of ACAN have been reported to cause spondyloepiphyseal dysplasia Kimberley type, spondyloepimetaphyseal dysplasia, familial osteochondritis dissecans and idiopathic short stature with normal to advanced bone age. A recent international cohort study significantly expanded the ACAN mutation spectrum, further delineated the heterogeneous clinical characteristics of ACAN mutation patients. The prevalence of ACAN mutation in short stature patients is yet unknown...
April 7, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28394713/elbow-mri-findings-do-not-correlate-with-future-placement-on-the-disabled-list-in-asymptomatic-professional-baseball-pitchers
#18
Nicholas M Gutierrez, Christopher Granville, Lee Kaplan, Michael Baraga, Jean Jose
BACKGROUND: Injury rates among professional baseball players may reach as high as 5.8 per 1000 encounters, with pitchers being most vulnerable on account of the excessive biomechanical load on the upper extremity during the throwing motion. Anatomically, the shoulder is the most common site of pitching-related injury, accounting for 30.7% of injuries, closely followed by the elbow at 26.3%. Characteristic valgus loading imparts a predictable constellation of stresses on the joint, including medial tension, lateral compression, and posterior medial shearing...
April 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28391550/donor-site-morbidity-after-osteochondral-autologous-transplantation-for-osteochondritis-dissecans-of-the-capitellum-a-systematic-review-and-meta-analysis
#19
REVIEW
Rens Bexkens, Paul T Ogink, Job N Doornberg, Gino M M J Kerkhoffs, Denise Eygendaal, Luke S Oh, Michel P J van den Bekerom
PURPOSE: To determine the rate of donor-site morbidity after osteochondral autologous transplantation (OATS) for capitellar osteochondritis dissecans. METHODS: A literature search was performed in PubMed/MEDLINE, Embase, and Cochrane Library to identify studies up to November 6, 2016. Criteria for inclusion were OATS for capitellar osteochondritis dissecans, reported outcomes related to donor sites, ≥10 patients, ≥1 year follow-up, and written in English. Donor-site morbidity was defined as persistent symptoms (≥1 year) or cases that required subsequent intervention...
April 8, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28391436/parylene-scaffold-for-cartilage-lesion
#20
Carlos Eduardo da Silveira Franciozi, Carleton Thomas Vangsness, James Eugene Tibone, Juan Carlos Martinez, Damien Rodger, Tzu-Chieh Chou, Yu-Chong Tai, Rodrigo Brant, Ling Wu, Rene Jorge Abdalla, Bo Han, Denis Evseenko, Mark Humayun
Evaluate parylene scaffold feasibility in cartilage lesion treatment, introducing a novel paradigm combining a reparative and superficial reconstructive procedure. Fifteen rabbits were used. All animals had both knees operated and the same osteochondral lesion model was created bilaterally. The parylene scaffold was implanted in the right knee, and the left knee of the same animal was used as control. The animals were euthanized at different time points after surgery: four animals at three weeks, three animals at six weeks, four animals at nine weeks, and four animals at 12 weeks...
June 2017: Biomedical Microdevices
keyword
keyword
25895
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"