Eva Maria Martin, Annie Srowig, Isabelle Utech, Simon Schrenk, Fabian Kattlun, Monique Radscheidt, Stefan Brodoehl, Peter Bublak, Matthias Schwab, Christian Geis, Bianca Besteher, Philipp A Reuken, Andreas Stallmach, Kathrin Finke
BACKGROUND: Fatigue is a frequent and one of the most debilitating symptoms in post-COVID syndrome (PCS). Recently, we proposed that fatigue is caused by hypoactivity of the brain's arousal network and reflected by a reduction of cognitive processing speed. However, it is unclear whether cognitive slowing is revealed by standard neuropsychological tests, represents a selective deficit, and how it develops over time. OBJECTIVES: This prospective study assesses whether PCS patients show deficits particularly in tests relying on processing speed and provides the first longitudinal assessment focusing on processing speed in PCS patients...
November 7, 2023: Journal of Neurology