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Reaction time testing in neuropsychology

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https://www.readbyqxmd.com/read/28391035/selective-verbal-recognition-memory-impairments-are-associated-with-atrophy-of-the-language-network-in-non-semantic-variants-of-primary-progressive-aphasia
#1
Aneesha S Nilakantan, Joel L Voss, Sandra Weintraub, M-Marsel Mesulam, Emily J Rogalski
Primary progressive aphasia (PPA) is clinically defined by an initial loss of language function and preservation of other cognitive abilities, including episodic memory. While PPA primarily affects the left-lateralized perisylvian language network, some clinical neuropsychological tests suggest concurrent initial memory loss. The goal of this study was to test recognition memory of objects and words in the visual and auditory modality to separate language-processing impairments from retentive memory in PPA...
April 6, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28356743/dynamic-balance-in-children-with-attention-deficit-hyperactivity-disorder-and-its-relationship-with-cognitive-functions-and-cerebellum
#2
Michal Goetz, Jaroslava Paulasova Schwabova, Zdenek Hlavka, Radek Ptacek, Craig Bh Surman
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is linked to the presence of motor deficiencies, including balance deficits. The cerebellum serves as an integrative structure for balance control and is also involved in cognition, including timing and anticipatory regulation. Cerebellar development may be delayed in children and adolescents with ADHD, and inconsistent reaction time is commonly seen in ADHD. We hypothesized that dynamic balance deficits would be present in children with ADHD and they would correlate with attention and cerebellar functions...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28355353/influence-of-schooling-and-age-on-cognitive-performance-in-healthy-older-adults
#3
N V O Bento-Torres, J Bento-Torres, A M Tomás, V O Costa, P G R Corrêa, C N M Costa, N Y V Jardim, C W Picanço-Diniz
Few studies have examined the influence of a low level of schooling on age-related cognitive decline in countries with wide social and economic inequalities by using the Cambridge Automated Neuropsychological Test Battery (CANTAB). The aim of the present study was to assess the influence of schooling on age-related cognitive decline using unbiased cognitive tests. CANTAB allows cognitive assessment across cultures and education levels with reduced interference of the examiner during data acquisition. Using two-way ANOVA, we assessed the influences of age and education on test scores of old adults (61-84 years of age)...
March 23, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28298013/does-subjective-improvement-in-adults-with-intracranial-arachnoid-cysts-justify-surgical-treatment
#4
Katrin Rabiei, Per Hellström, Mats Högfeldt-Johansson, Magnus Tisell
OBJECTIVE Subjective improvement of patients who have undergone surgery for intracranial arachnoid cysts has justified surgical treatment. The current study aimed to evaluate the outcome of surgical treatment for arachnoid cysts using standardized interviews and assessments of neuropsychological function and balance. The relationship between arachnoid cyst location, postoperative improvement, and arachnoid cyst volume was also examined. METHODS The authors performed a prospective, population-based study. One hundred nine patients underwent neurological, neuropsychological, and physiotherapeutic examinations...
February 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28293481/a-genetic-variant-within-sts-previously-associated-with-inattention-in-boys-with-attention-deficit-hyperactivity-disorder-is-associated-with-enhanced-cognition-in-healthy-adult-males
#5
Trevor Humby, Amelia Fisher, Christopher Allen, Meghann Reynolds, Annette Hartman, Ina Giegling, Dan Rujescu, William Davies
INTRODUCTION: The enzyme steroid sulfatase (STS) converts sulfated steroids to their non-sulfated forms. Deficiency for this enzyme is associated with inattention but preserved response control. The polymorphism rs17268988 within the X-linked STS gene is associated with inattentive, but not other, symptoms in boys with attention deficit hyperactivity disorder (ADHD). METHODS: We initially tested whether rs17268988 genotype was associated with attention, response control, and underlying aspects of cognition, using questionnaires and neuropsychological tasks, in two independent cohorts of healthy adult males...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28293109/effects-of-a-structured-20-session-slow-cortical-potential-based-neurofeedback-program-on-attentional-performance-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-retrospective-analysis-of-an-open-label-pilot-approach-and-6-month-follow
#6
Johanna S Albrecht, Sarah Bubenzer-Busch, Anne Gallien, Eva Lotte Knospe, Tilman J Gaber, Florian D Zepf
OBJECTIVE: The aim of this approach was to conduct a structured electroencephalography-based neurofeedback training program for children and adolescents with attention-deficit hyperactivity disorder (ADHD) using slow cortical potentials with an intensive first (almost daily sessions) and second phase of training (two sessions per week) and to assess aspects of attentional performance. PATIENTS AND METHODS: A total of 24 young patients with ADHD participated in the 20-session training program...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28238393/preliminary-evidence-of-improved-cognitive-performance-following-vestibular-rehabilitation-in-children-with-combined-adhd-cadhd-and-concurrent-vestibular-impairment
#7
Younes Lotfi, Nima Rezazadeh, Abdollah Moossavi, Hojjat Allah Haghgoo, Reza Rostami, Enayatollah Bakhshi, Faride Badfar, Sedigheh Farokhi Moghadam, Vahid Sadeghi-Firoozabadi, Yousef Khodabandelou
OBJECTIVE: Balance function has been reported to be worse in ADHD children than in their normal peers. The present study hypothesized that an improvement in balance could result in better cognitive performance in children with ADHD and concurrent vestibular impairment. This study was designed to evaluate the effects of comprehensive vestibular rehabilitation therapy on the cognitive performance of children with combined ADHD and concurrent vestibular impairment. METHODS: Subject were 54 children with combined ADHD...
February 18, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28236259/a-retrospective-cross-sectional-and-longitudinal-study-of-the-effects-of-age-on-cns-vital-signs-scores-in-high-school-athletes
#8
Sharon D Rogers, Patrick J Smith, Alexandra J Stephenson, D Erik Everhart
INTRODUCTION: Current recommendations for concussion management acknowledge the importance of objective assessments of neuropsychological (NP) ability, and computerized NP assessments have been widely integrated into the concussion management protocols of high schools. The optimal intervals for baseline test administration in high-school athletes are currently uncertain. The ability to accurately detect subtle NP deficits is particularly important for high-school athletes, in which concussions are increasingly recognized for adverse effects to the developing brain...
February 24, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28231478/event-related-brain-potential-indices-of-cognitive-function-and-brain-resource-reallocation-during-working-memory-in-patients-with-multiple-sclerosis
#9
Thomas J Covey, Janet L Shucard, David W Shucard
OBJECTIVE: To examine event-related brain potentials (ERPs) in Multiple Sclerosis (MS) during a visual n-back working memory (WM) task, and test the hypothesis that compensatory brain function may be associated with variance in task performance in MS patients. METHODS: Midline ERPs for 25MS patients and 18 HCs were obtained for a visual n-back task that placed increasing demands on WM. N-back behavioral measures and neuropsychological performance measures of WM were also obtained...
April 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28215191/is-computerized-cognitive-testing-useful-in-children-and-adolescents-with-moderate-to-severe-traumatic-brain-injury
#10
Vickie Plourde, Brian L Brooks
OBJECTIVES: Children and adolescents with moderate-to-severe traumatic brain injury (TBI) present with short and long-term neuropsychological deficits following their injury. The aim of this study was to investigate the utility of a brief computerized test battery for evaluating cognitive functioning sub-acutely following a TBI. METHODS: Participants (n=33) sustained a moderate-to-severe TBI, were between 8 and 18 years old, and were assessed using CNS Vital Signs (CNSVS) within 6 months post-injury (median=0...
February 20, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28197651/effects-of-early-life-stress-and-adolescent-ethanol-exposure-on-adult-cognitive-performance-in-the-5-choice-serial-reaction-time-task-in-wistar-male-rats
#11
Nathalie Boutros, Andre Der-Avakian, Athina Markou, Svetlana Semenova
RATIONALE: Early life stress combined with heavy adolescent alcohol use predicts impaired neuropsychological functioning in adulthood. We investigated whether adolescent intermittent ethanol (AIE) exposure combined with neonatal maternal separation in rats altered attentional processes and impulsivity in adulthood. METHODS: Male Wistar rat pups were exposed to maternal separation (postnatal days (PNDs) 1-14) and moderate AIE exposure (PNDs 28-57). Adult rats were tested in the five-choice serial reaction time task, which provides separate measures of attention, motor impulsivity, and compulsivity...
February 14, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28196313/executive-functioning-at-baseline-prospectively-predicts-depression-treatment-response
#12
Erica L Dawson, Angela F Caveney, Kortni K Meyers, Sara L Weisenbach, Bruno Giordani, Erich T Avery, Michael-Paul Schallmo, Armita Bahadori, Linas A Bieliauskas, Matthew Mordhorst, Sheila M Marcus, Kevin Kerber, Jon-Kar Zubieta, Scott A Langenecker
Objective: Existing cognitive and clinical predictors of treatment response to date are not of sufficient strength to meaningfully impact treatment decision making and are not readily employed in clinical settings. This study investigated whether clinical and cognitive markers used in a tertiary care clinic could predict response to usual treatment over a period of 4 to 6 months in a sample of 75 depressed adults. Methods: Patients (N = 384) were sequentially tested in 2 half-day clinics as part of a quality improvement project at an outpatient tertiary care center between August 2003 and September 2007; additional subjects evaluated in the clinic between 2007 and 2009 were also included...
February 9, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28183402/the-effects-of-acute-inflammation-on-cognitive-functioning-and-emotional-processing-in-humans-a-systematic-review-of-experimental-studies
#13
REVIEW
Jessica Bollen, Leanne Trick, David Llewellyn, Chris Dickens
OBJECTIVE: The cognitive neuropsychological model of depression proposes that negative biases in the processing of emotionally salient information have a central role in the development and maintenance of depression. We have conducted a systematic review to determine whether acute experimental inflammation is associated with changes to cognitive and emotional processing that are thought to cause and maintain depression. METHODS: We identified experimental studies in which healthy individuals were administered an acute inflammatory challenge (bacterial endotoxin/vaccination) and standardised tests of cognitive function were performed...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28122770/factor-structure-of-impact%C3%A2-in-adolescent-student-athletes
#14
Paul B Gerrard, Grant L Iverson, Joseph E Atkins, Bruce A Maxwell, Ross Zafonte, Philip Schatz, Paul D Berkner
OBJECTIVE: ImPACT(®) (Immediate Post-Concussion Assessment and Cognitive Testing) is a computerized neuropsychological screening battery, which is widely used to measure the acute effects of sport-related concussion and to monitor recovery from injury. This study examined the factor structure of ImPACT(®) in several samples of high school student athletes. We hypothesized that a 2-factor structure would be present in all samples. METHOD: A sample of 4,809 adolescent student athletes was included, and subgroups with a history of treatment for headaches or a self-reported history of learning problems or attention-deficit hyperactivity disorder were analyzed separately...
February 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28117613/relation-between-serum-leptin-levels-lipid-profiles-and-neurocognitive-deficits-in-chinese-osahs-patients
#15
Yating Peng, Li Zhou, Yuping Cao, Ping Chen, Yan Chen, Dandan Zong, Ruoyun Ouyang
OBJECTIVE: The aim of this study was to compare serum leptin, apolipoprotein A1 (ApoA1), apolipoprotein J (ApoJ) and apolipoprotein H (ApoH) levels in males with obstructive sleep apnea and hypopnea syndrome (OSAHS) to those in healthy control subjects and to examine the possible relation between neurocognitive performance and these factors/serum markers in the subjects. METHODS: In this observational, cross-sectional study, a full-night polysomnography and sensitive neuropsychological assessment were performed on 50 newly diagnosed Chinese male patients and 30 healthy subjects...
February 13, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28066966/updating-neuropsychological-test-system-for-the-elderly-and-modern-touch-screen-tablet-society-by-resetting-of-the-cut-off-values
#16
Takumi Kawaguchi, Mika Konishi, Akinobu Kato, Motoichiro Kato, Yohei Kooka, Kei Sawara, Ryujin Endo, Takuji Torimura, Kazuyuki Suzuki, Yasuhiro Takikawa
BACKGROUND & AIMS: Covert hepatic encephalopathy (CHE) is frequently seen in cirrhotic patients. CHE can be diagnosed by a computerized neuropsychological test system (NPT); however, NPT has not been updated about two decades in Japan. The aim of this study is to update the NPT for fitting the elderly and modern society by resetting of the cut-off values. METHODS: We enrolled 367 healthy subjects with 40 to 79 years old between 2003 and 2010. NPT consist of following 8 tests: number connection tests A and B, a figure position test, a digit symbol test, a block design test, and reaction time test A, B, and C...
January 8, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28001452/test-retest-reliability-of-five-frequently-used-executive-tasks-in-healthy-adults
#17
Anna Soveri, Minna Lehtonen, Linda C Karlsson, Karolina Lukasik, Jan Antfolk, Matti Laine
Executive tasks are important instruments for neuropsychological and cognitive research, but only a limited number of studies have investigated the test-retest reliability of these tasks. Such information is needed for optimizing task usage, for example, in longitudinal and intervention studies. In this study with healthy adults, we investigated the temporal stability of five executive tasks: the Simon task, a visuoverbal N-back task, a visuospatial N-back task, a running memory task, and the Number-letter task...
December 21, 2016: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/27992286/the-role-of-gender-in-neuropsychological-assessment-in-healthy-adolescents
#18
Megan Elizabeth Evelyn Mormile, Tamerah N Hunt
Research in collegiate athletes has revealed significant gender differences in areas of verbal memory, visual memory, and reaction time. Additionally, research has focused on differences in neuropsychological components and gender in collegiate populations; however, such differences in gender have not been documented in healthy adolescent populations. PURPOSE: The purpose of this study was to identify potential differences between males and females using different components of a common computerized neuropsychological test...
December 19, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27932344/using-robust-normative-data-to-investigate-the-neuropsychology-of-cognitive-aging
#19
Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Stephanie Rainey-Smith, Joanne Robertson, Olivier Salvado, Colin L Masters, Paul Maruff
Objective: The extent to which increasing age is associated with impairment in cognitive function, termed cognitive aging, may have been overestimated in prior studies. The inclusion of individuals with severe or uncontrolled systemic medical illness or prodromal neurodegenerative disease in normal aging samples is likely to bias estimates toward lower cognitive performance and inflate estimates of variability. Method: Unbiased estimates of cognitive aging in 658 adults aged 60-84, who underwent rigorous screening to ensure their general and cognitive health, were computed...
March 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/27927083/measurement-of-peripheral-vision-reaction-time-identifies-white-matter-disruption-in-patients-with-mild-traumatic-brain-injury
#20
Kyle B Womack, Christopher Paliotta, Jeremy F Strain, Johnson S Ho, Yosef Skolnick, William W Lytton, L Christine Turtzo, Roderick McColl, Ramon Diaz-Arrastia, Peter J Bergold
This study examined whether peripheral vision reaction time (PVRT) in patients with mild traumatic brain injury (mTBI) correlated with white matter abnormalities in centroaxial structures and impairments in neuropsychological testing. Within 24 h after mTBI, crossed reaction times (CRT), uncrossed reaction times (URT), and crossed-uncrossed difference (CUD) were measured in 23 patients using a laptop computer that displayed visual stimuli predominantly to either the left or the right visual field of the retina...
April 15, 2017: Journal of Neurotrauma
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