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Descemet's membrane

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https://www.readbyqxmd.com/read/28430178/endothelial-keratoplasty-is-descemet-membrane-endothelial-keratoplasty-the-holy-grail-of-lamellar-surgery-no
#1
M Tsatsos, V S Liarakos, C MacGregor, I Athanasiadis, E T Detorakis, M M Moschos, P Hossain, D F Anderson
No abstract text is available yet for this article.
April 21, 2017: Eye
https://www.readbyqxmd.com/read/28421398/supradescemetic-voriconazole-injection-for-candida-parapsilosis-keratitis
#2
Nikolaos Mamas, Konstantinos Andreanos, Klio Chatzistefanou, Petros Petrou, Dimitrios Brouzas, George Kymionis, Chrysanthi Koutsandrea, Konstantinos Droutsas
PURPOSE: To describe a technique for intracorneal application of voriconazole into the supradescemetic space in a case of deep recalcitrant Candida parapsilosis keratitis of a penetrating cornea graft. METHODS: A deep intracorneal incision reaching the center of the corneal infiltrate was created with a 20-gauge MVR blade. Then, a 27-gauge hydrodissection cannula was inserted deep into the corneal pocket, and 0.1 ml of voriconazole 0.5 mg/ml was injected until a bullous detachment of Descemet membrane (DM) covered 1/3 of the graft's area...
April 18, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28417337/descemet-stripping-automated-endothelial-keratoplasty-versus-descemet-membrane-endothelial-keratoplasty-a-meta-analysis
#3
REVIEW
Leru Zhu, Yi Zha, Jianqiu Cai, Yanling Zhang
PURPOSE: To evaluate the efficacy and safety of descemet stripping automated endothelial keratoplasty (DSAEK) compared with descemet membrane endothelial keratoplasty (DMEK). METHODS: Databases including PubMed, EMBASE, and Cochrane Library were searched to find studies that compared DSAEK and DMEK outcomes. Efficacy parameters were the postoperative best-corrected visual acuity (BCVA) and spherical equivalent (SE). Safety parameters were postoperative endothelial cell loss (ECL), air injection (rebubbling), graft failure, graft rejection, and high intraocular pressure (IOP)...
April 17, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28416495/ultrastructural-study-of-peripheral-and-central-stroma-of-keratoconus-cornea
#4
Aljoharah Alkanaan, Robert Barsotti, Omar Kirat, Turki Almubrad, Adnan Khan, Saeed Akhtar
PURPOSE: Assess the lamellar organisation of the peripheral and central stroma of the keratoconus (KC) and normal cornea. METHODS: Five normal and three KC corneas were fixed in 2.5% glutaraldehyde and processed for electron microscopy. The ultrathin sections were observed under JEOL 1400 TEM, and digital images were taken with a bottom-mounted 11-megapixel Quamisa camera, using the iTEM software. Measurements of the lamellae were carried out using the iTEM software...
April 17, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28410548/two-year-clinical-outcome-of-500-consecutive-cases-undergoing-descemet-membrane-endothelial-keratoplasty
#5
Jorge Peraza-Nieves, Lamis Baydoun, Isabel Dapena, Abbas Ilyas, Laurence E Frank, Salvatore Luceri, Lisanne Ham, Silke Oellerich, Gerrit R J Melles
PURPOSE: To evaluate the clinical outcome of 500 consecutive cases up to 2 years after Descemet membrane endothelial keratoplasty (DMEK) and to assess which parameters may have influenced the clinical outcome. METHODS: From a group of 500 eyes (393 patients), which underwent DMEK for Fuchs endothelial corneal dystrophy (FECD), bullous keratopathy, failed corneal transplants and other indications, clinical outcomes [best-corrected visual acuity (BCVA), central endothelial cell density (ECD), and central corneal thickness] were evaluated before, and at 6, 12, and 24 months after DMEK and postoperative complications were documented...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410359/intraoperative-s-stamp-enabled-rescue-of-3-inverted-descemet-membrane-endothelial-keratoplasty-grafts
#6
Peter B Veldman, Zachary M Mayko, Michael D Straiko, Mark A Terry
PURPOSE: To report the clinical outcomes of 3 Descemet membrane endothelial keratoplasty (DMEK) grafts, in which an upside down DMEK graft orientation was discovered after SF6 gas insufflation of the anterior chamber and the orientation was then corrected intraoperatively. METHODS: A total of 371 consecutive DMEK cases using an S-stamp were analyzed and found to include 3 cases in which the DMEK graft was initially elevated with SF6 gas in an upside down orientation, as demonstrated intraoperatively by the S-stamp...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28405478/comparison-of-outcomes-in-patients-who-underwent-deep-anterior-lamellar-keratoplasty-and-those-converted-to-penetrating-keratoplasty
#7
Yusuf Koçluk, Emine Alyamaç Sukgen, Ayşe Burcu
OBJECTIVES: To compare clinical outcomes of cases who underwent deep anterior lamellar keratoplasty (DALK) and cases who were converted to penetrating keratoplasty (PKP) from DALK surgery. MATERIALS AND METHODS: The records of 54 patients for whom DALK surgery was planned and were operated for different diagnoses between March 2013 and June 2015 were retrospectively analyzed. Patients were divided into two groups: group 1 (PKP group) consisted of 23 cases who were converted to PKP due to Descemet's membrane perforation at any stage of surgery; group 2 (DALK group) consisted of 31 patients whose surgery could be completed as DALK...
April 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28400886/corneal-toxicity-following-exposure-to-asclepias-tuberosa
#8
Lauge Hjorth Mikkelsen, Hassan Hamoudi, Cigdem Altuntas Gül, Steffen Heegaard
PURPOSE: To present a case of corneal toxicity following exposure to milky plant latex from Asclepias tuberosa. METHODS: A 70-year-old female presented with blurred vision and pain in her left eye after handling an Ascepias tuberosa. Clinical examination revealed a corneal stromal oedema with small epithelial defects. The corneal endothelium was intact and folds in Descemets membrane were observed. The oedema was treated with chloramphenicol, dexamethasone and scopolamine...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28399068/descemet-membrane-endothelial-keratoplasty-and-refractive-surgery
#9
C Maya Tong, Lamis Baydoun, Gerrit R J Melles
PURPOSE OF REVIEW: Descemet membrane endothelial keratoplasty (DMEK) has become a first-line treatment in corneal endothelial diseases because of its exceptional clinical outcomes and low complication rates. Because of its improved refractive predictability, DMEK is now also considered for managing cases with endothelial decompensation following previous refractive procedures, or in combination with those. This article reviews the clinical outcomes in these cases and discusses the possibility of refractive interventions following DMEK...
April 8, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28399038/intraoperative-optical-coherence-tomography-assisted-descemet-stripping-automated-endothelial-keratoplasty-for-anterior-chamber-fibrous-ingrowth
#10
Tarek A Shazly, Lillian K To, Ian P Conner, Ladan Espandar
PURPOSE: Here, we present the first reported case of intraoperative optical coherence tomography (OCT)-assisted Descemet membrane stripping automated endothelial keratoplasty (DSAEK) in a patient with anterior segment fibrous ingrowth. METHODS: A 61-year-old woman with corneal edema and chronic angle-closure glaucoma secondary to fibrous ingrowth after 2 glaucoma shunt device implantations underwent dissection and removal of anterior chamber fibrous ingrowth and DSAEK...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28395029/mitochondrial-and-morphologic-alterations-in-native-human-corneal-endothelial-cells-associated-with-diabetes-mellitus
#11
Benjamin T Aldrich, Ursula Schlötzer-Schrehardt, Jessica M Skeie, Kimberlee A Burckart, Gregory A Schmidt, Cynthia R Reed, M Bridget Zimmerman, Friedrich E Kruse, Mark A Greiner
Purpose: To characterize changes in the energy-producing metabolic activity and morphologic ultrastructure of corneal endothelial cells associated with diabetes mellitus. Methods: Transplant suitable corneoscleral tissue was obtained from donors aged 50 to 75 years. We assayed 3-mm punches of endothelium-Descemet membrane for mitochondrial respiration and glycolysis activity using extracellular flux analysis of oxygen and pH, respectively. Transmission electron microscopy was used to assess qualitative and quantitative ultrastructural changes in corneal endothelial cells and associated Descemet membrane...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28393029/comparison-of-visual-and-topographic-outcomes-of-deep-anterior-lamellar-keratoplasty-and-penetrating-keratoplasty-in-keratoconus
#12
Bora Yüksel, Baran Kandemir, Umut Duygu Uzunel, Ozan Çelik, Sezgin Ceylan, Tuncay Küsbeci
AIM: To compare visual, surgical and topographic outcomes of deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) for keratoconus (KC). METHODS: In this multicenter, prospective, randomized clinical trial 76 eyes of 71 KC patients operated between January 2011 and July 2014 in 2 tertiary referral hospitals were included. Consecutive patients were alternately selected to receive one of the two surgical methods. Thirty eight eyes underwent DALK with the big-bubble technique and 38 eyes underwent PK...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28391370/descemet-membrane-endothelial-keratoplasty-dmek-early-stage-graft-failure-in-eyes-with-preexisting-glaucoma
#13
Maximilian Treder, Maged Alnawaiseh, Nicole Eter
PURPOSE: To evaluate the effect of a preexisting glaucoma on the early postoperative outcome of a descemet membrane endothelial keratoplasty (DMEK). METHODS: All patients who underwent DMEK surgery at the Department of Ophthalmology of the University of Muenster with a follow-up of at least 3 months (90d) were included in this study. The best corrected distance visual acuity (BCDVA), the intraocular pressure (IOD), the rate of re-keratoplasty and the rebubbling rate were inter alia recorded...
April 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28387760/endothelial-keratoplasty-is-descemet-membrane-endothelial-keratoplasty-the-way-forward-yes
#14
V S Liarakos, M Tsatsos, M Satue, G R J Melles
No abstract text is available yet for this article.
April 7, 2017: Eye
https://www.readbyqxmd.com/read/28379650/the-effect-of-eye-patching-on-clear-corneal-incision-architecture-in-phacoemulsification-a-randomized-controlled-trial
#15
Fui Li Ho, Mohamad Aziz Salowi, Mae-Lynn Catherine Bastion
PURPOSE: To investigate the effects of postoperative eye patching on clear corneal incision architecture in phacoemulsification. DESIGN: A single-center, randomized controlled trial. METHODS: A total of 132 patients with uncomplicated phacoemulsification were randomly allocated to the intervention or control group. The intervention group received postoperative eye patching for approximately 18 hours, whereas the control group received eye shield...
March 29, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28368994/revisiting-the-cornea-and-trabecular-meshwork-junction-with-2-photon-excitation-fluorescence-microscopy
#16
Catherine M Marando, Choul Yong, Jason A Liao, Jimmy K Lee, Roy S Chuck
PURPOSE: To investigate the collagen and elastin architecture at the junction of the human cornea and trabecular meshwork (TM). METHODS: The cornea, TM, and ciliary body (CB) tendons of unfixed human corneal buttons were imaged with an inverted 2-photon excited fluorescence microscope (FluoView FV-1000; Olympus, Central Valley, PA). The laser (Ti:sapphire) was tuned to 850 nm for 2-photon excitation. Backscatter signals of second harmonic generation and autofluorescence were collected through a 425/30-nm emission filter and a 525/45-nm emission filter, respectively...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28350625/outcome-and-histopathology-of-secondary-penetrating-keratoplasty-graft-failure-managed-by-descemet-membrane-endothelial-keratoplasty
#17
Itay Lavy, Vasilios S Liarakos, Robert M Verdijk, Jack Parker, Thomas M Müller, Marieke Bruinsma, Perry S Binder, Gerrit R J Melles
PURPOSE: To describe the clinical outcome and histopathology of Descemet membrane endothelial keratoplasty (DMEK) performed for secondary graft failure after penetrating keratoplasty (PK). METHODS: A total of 11 eyes from 10 patients who underwent DMEK for secondary PK graft failure at a tertiary referral center were included in this retrospective study. Best-corrected visual acuity, endothelial cell density, and central pachymetry were evaluated before and at regular time intervals up to 36 months after DMEK and complications were recorded; 1 post mortem cornea was available for light microscopy...
March 21, 2017: Cornea
https://www.readbyqxmd.com/read/28345566/intraoperative-optical-coherence-tomography-in-anterior-segment-surgeries
#18
Jeewan S Titiyal, Manpreet Kaur, Ruchita Falera
Intraoperative optical coherence tomography (iOCT) is a noninvasive imaging modality that provides a real-time dynamic feedback of the various surgical steps. Comprehensive literature search was performed in MEDLINE using "intraoperative optical coherence tomography" and "iOCT" as keywords. The use of iOCT as an aid to decision-making has been successfully reported in cases undergoing keratoplasty, implantable Collamer lens (ICL) implantation as well as cataract surgery. iOCT helps to assess the graft-host relationship in penetrating keratoplasty...
February 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28342720/rebubbling-in-descemet-membrane-endothelial-keratoplasty-influence-of-pressure-and-duration-of-the-intracameral-air-tamponade
#19
Daniel Pilger, Ina Wilkemeyer, Jan Schroeter, Anna-Karina B Maier, Necip Torun
PURPOSE: To explore the impact of intracameral air tamponade pressure and duration on graft attachment and rebubbling rates. DESIGN: A prospective, interventional, non-randomized study METHODS: Setting: Charité - Universitätsmedizin Berlin, department of ophthalmology STUDY POPULATION: 117 patients who underwent Descemet membrane endothelial keratoplasty (DMEK) OBSERVATION: Intraocular pressure (IOP) at the end of the surgery, immediately after filling the anterior chamber with air, categorized into low (<10mmHg), normal (10-20mmHg) and high (>20mmHg) and the time until partial removal of the air...
March 22, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28337067/late-spontaneous-resolution-of-a-double-anterior-chamber-post-deep-anterior-lamellar-keratoplasty
#20
Andrea Passani, Angela Tindara Sframeli, Pasquale Loiudice, Marco Nardi
A 31-year-old healthy male underwent deep anterior lamellar keratoplasty with big-bubble technique for treatment of keratoconus in his right eye. One week after surgery, he presented with detachment of the endothelium-Descemet complex with formation of a double anterior chamber, despite the apparent absence of an intraoperative Descemet membrane rupture. A subsequent intervention with the intent to relocate the corneal graft button was not effective, because the detachment appeared again one day later. The authors hypothesized that, at the time of the stromal dissection with big bubble technique, a small amount of air penetrated into the anterior chamber, creating a false pathway through the trabecular meshwork...
January 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
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