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https://www.readbyqxmd.com/read/28323626/pomegranate-punica-granatum-seed-oil-for-treating-menopausal-symptoms-an-individually-controlled-cohort-study
#1
Roman Huber, Richard Gminski, Tao Tang, Tomas Weinert, Sabine Schulz, Margareta Linke-Cordes, Ines Martin, Heide Fischer
Context • In the folk medicine of Mediterranean countries and in ancient Ayurveda, Punica granatum seeds (ie, pomegranate seeds) have been used for treatment of various disorders, including those that nowadays are classified as menopausal symptoms (MSs). Pomegranate seed oil (PSO) from those seeds mainly contains unsaturated fatty acids such as γ-linoleic acid and linolenic acid, but it also includes phytoestrogens. It is, therefore, regarded as a promising option for treating MSs today. Objectives • The study intended to investigate the safety and effectiveness of PSO as a defined P granatum seed oil for patients with MSs...
March 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28320100/drosophila-melanogaster-a-potential-model-organism-for-identification-of-pharmacological-properties-of-plants-plant-derived-components
#2
REVIEW
Komal Panchal, Anand K Tiwari
Plants/plant-derived components have been used from ancient times to treat/cure several human diseases. Plants and their parts possess several chemical components that play the vital role in the improvement of human health and their life expectancy. Allopathic medicines have been playing a key role in the treatment of several diseases. Though allopathic medicines provide fast relief, long time consumption cause serious health concerns such as hyperallergic reactions, liver damage, etc. So, the study of medicinal plants which rarely cause any side effect is very important to mankind...
March 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28299201/lyssaviruses-and-rabies-current-conundrums-concerns-contradictions-and-controversies
#3
REVIEW
Charles Rupprecht, Ivan Kuzmin, Francois Meslin
Lyssaviruses are bullet-shaped, single-stranded, negative-sense RNA viruses and the causative agents of the ancient zoonosis rabies. Africa is the likely home to the ancestors of taxa residing within the Genus Lyssavirus, Family Rhabdoviridae. Diverse lyssaviruses are envisioned as co-evolving with bats, as the ultimate reservoirs, over seemingly millions of years. In terms of relative distribution, overt abundance, and resulting progeny, rabies virus is the most successful lyssavirus species today, but for unknown reasons...
2017: F1000Research
https://www.readbyqxmd.com/read/28293406/%C3%AE-thalassemia-distribution-in-the-old-world-an-ancient-disease-seen-from-a-historical-standpoint
#4
REVIEW
Vincenzo De Sanctis, Christos Kattamis, Duran Canatan, Ashraf T Soliman, Heba Elsedfy, Mehran Karimi, Shahina Daar, Yasser Wali, Mohamed Yassin, Nada Soliman, Praveen Sobti, Soad Al Jaouni, Mohamed El Kholy, Bernadette Fiscina, Michael Angastiniotis
BACKGROUND: Haemoglobinopathies constitute the commonest recessive monogenic disorders worldwide, and the treatment of affected individuals presents a substantial global disease burden. β-thalassaemia is characterised by the reduced synthesis (β(+)) or absence (β(o)) of the β-globin chains in the HbA molecule, resulting in accumulation of excess unbound α-globin chains that precipitate in erythroid precursors in the bone marrow and in the mature erythrocytes, leading to ineffective erythropoiesis and peripheral haemolysis...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28285613/ayurvedic-concept-of-shatkriyakala-a-traditional-knowledge-of-cancer-pathogenesis-and-therapy
#5
REVIEW
Ashutosh Chauhan, Deepak Kumar Semwal, Satyendra Prasad Mishra, Ruchi Badoni Semwal
The term Kriyakala refers to the recognition of the stage of a disease's progress, which helps to determine appropriate measure to correct the imbalance in Doshas (biological factors). It is a compound expression, comprised of Kriya and Kala, where Kriya means the choice to treatment (medicine, food and daily-routine) used to improve the disturbance in Doshas, and Kala refers to the stage of progress of a disease. Sushruta, an ancient Indian surgeon, has described the concept of Kriyakala in Varnaprashnadhyaya, an ancient Vedic Sanskrit text, which seeks to explain the incidence of Varnas in terms of Doshic disturbances...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28281107/cannabis-for-pain-and-headaches-primer
#6
REVIEW
Philip S Kim, Michael A Fishman
PURPOSE OF REVIEW: Marijuana has been used both medicinally and recreationally since ancient times and interest in its compounds for pain relief has increased in recent years. The identification of our own intrinsic, endocannabinoid system has laid the foundation for further research. RECENT FINDINGS: Synthetic cannabinoids are being developed and synthesized from the marijuana plant such as dronabinol and nabilone. The US Food and Drug Administration approved the use of dronabinol and nabilone for chemotherapy-associated nausea and vomiting and HIV (Human Immunodeficiency Virus) wasting...
April 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28266999/combination-of-panaxadiol-and-panaxatriol-type-saponins-and-ophioponins-from-shenmai-formula-attenuates-lipopolysaccharide-induced-inflammatory-injury-in-cardiac-microvascular-endothelial-cells-by-blocking-nf-kappa-b-pathway
#7
Jinqiang Zhu, Yubin Liang, Shaoqian Yue, Guanwei Fan, Han Zhang, Meng Zhang
Vascular inflammatory injury leads to vascular endothelial dysfunction, thereby resulting in a variety of cardiovascular diseases (CVDs). Thus, attenuating vascular inflammatory injury has great significance for the prevention and treatment of CVDs. In China, Shenmai formula, a well-known ancient Chinese prescription, has been widely used to treat CVDs, such as coronary atherosclerosis and viral myocarditis. In vivo study has demonstrated that the optimal combination of 3 major active components from Shenmai formula, panaxadiol and panaxatriol type saponins and ophioponins, in a ratio of 1:2:2 might exert significant cardioprotective effects and anti-inflammatory activities...
March 2017: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/28265784/-all-i-need-is-help-to-do-well-herbs-medicines-faith-and-syncretism-in-the-negotiation-of-elder-health-treatment-in-rural-ghana
#8
Eileen Smith-Cavros, Joyce Avotri-Wuaku, Albert Wuaku, Amal Bhullar
This qualitative research sought answers to questions about how elders in Agate, Ghana, coped with the challenges of illness in a rural village and in particular how they negotiated treatment for their illnesses within a flawed and limited healthcare system. In our study, 22 of 28 interviewees used all methods available to them (biomedical approaches [doctors and/or hospitals and/or doctor-prescribed medications], herbs, over-the-counter medicines [i.e., acetaminophen painkillers], and faith-based methods [praying/fasting/laying of hands/holy food and/or water]) in attempts to heal their illnesses...
March 6, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28263320/insect-symbiotic-bacteria-harbour-viral-pathogens-for-transovarial-transmission
#9
Dongsheng Jia, Qianzhuo Mao, Yong Chen, Yuyan Liu, Qian Chen, Wei Wu, Xiaofeng Zhang, Hongyan Chen, Yi Li, Taiyun Wei
Many insects, including mosquitoes, planthoppers, aphids and leafhoppers, are the hosts of bacterial symbionts and the vectors for transmitting viral pathogens(1-3). In general, symbiotic bacteria can indirectly affect viral transmission by enhancing immunity and resistance to viruses in insects(3-5). Whether symbiotic bacteria can directly interact with the virus and mediate its transmission has been unknown. Here, we show that an insect symbiotic bacterium directly harbours a viral pathogen and mediates its transovarial transmission to offspring...
March 6, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28260045/a-herbal-formula-sykt-reverses-doxorubicin%C3%A2-induced-myelosuppression-and-cardiotoxicity-by-inhibiting-ros%C3%A2-mediated-apoptosis
#10
Ting Chen, Hong-Mei Shen, Zhi-Yong Deng, Zuo-Zhang Yang, Rui-Lian Zhao, Li Wang, Zhi-Ping Feng, Chao Liu, Wen-Hui Li, Zhi-Jie Liu
Doxorubicin (DOX) is an antineoplastic drug widely used for the treatment of various types of cancer; however, it can induce severe side effects, such as myelosuppression and cardiotoxicity. Sanyang Xuedai (SYKT) is a natural medicine originating from an ancient prescription of the Dai nationality in Southwest China. With eight Chinese herbal medicines, including sanguis draconis, radix et rhizoma notoginseng, radix et rhizoma glycyrrhizae and radix angelicae sinensis as the primary ingredients, SYKT has been reported to possess numerous biological functions...
March 1, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28254675/from-ancient-herb-to-modern-drug-artemisia-annua-and-artemisinin-for-cancer-therapy
#11
REVIEW
Thomas Efferth
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been developed as antimalarial drug and is used worldwide. Interestingly, the bioactivity is not restricted to malaria treatment. We and others found that ARS-type drugs also reveal anticancer in vitro and in vivo. In this review, we give a systematic overview of the literature published over the past two decades until the end of 2016...
February 28, 2017: Seminars in Cancer Biology
https://www.readbyqxmd.com/read/28250906/zika-virus-diseases-the-new-face-of-an-ancient-enemy-as-global-public-health-emergency-2016-brief-review-and-recent-updates
#12
REVIEW
Deepak Passi, Sarang Sharma, Shubha Ranjan Dutta, Musharib Ahmed
Zika virus (ZIKV) disease is caused by a virus transmitted by Aedes mosquito. It presents as flu-like symptoms lasting for 5-7 days and shows potential association with neurological and autoimmune complications such as congenital microcephaly and adult paralysis disorder, Guillain-Barré syndrome. Treatment measures are conservative as the disease is self-limiting. ZIKV earlier affected several tropical regions of Africa and Asia from 1951 to 2006. Subsequently, it moved out from these regions to land as outbreaks in Yap Island, French Polynesia, South America, and most recently in Brazil...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28221130/whole-genome-analysis-of-bartonella-ancashensis-a-novel-pathogen-causing-verruga-peruana-rural-ancash-region-peru
#13
Kristin E Mullins, Jun Hang, Robert J Clifford, Fatma Onmus-Leone, Yu Yang, Ju Jiang, Mariana Leguia, Matthew R Kasper, Ciro Maguina, Emil P Lesho, Richard G Jarman, Allen Richards, David Blazes
The genus Bartonella contains >40 species, and an increasing number of these Bartonella species are being implicated in human disease. One such pathogen is Bartonella ancashensis, which was isolated in blood samples from 2 patients living in Caraz, Peru, during a clinical trial of treatment for bartonellosis. Three B. ancashensis strains were analyzed by using whole-genome restriction mapping and high-throughput pyrosequencing. Genome-wide comparative analysis of Bartonella species showed that B. ancashensis has features seen in modern and ancient lineages of Bartonella species and is more related to B...
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28216890/evaluate-the-antigenotoxicity-and-anticancer-role-of-%C3%AE-sitosterol-by-determining-oxidative-dna-damage-and-the-expression-of-phosphorylated-mitogen-activated-protein-kinases-c-fos-c-jun-and-endothelial-growth-factor-receptor
#14
Ramalingam Sharmila, Ganapathy Sindhu
BACKGROUND: Plant sterols are the major source of micronutrients and have not shown any obvious side effects in human. β-sitosterol is one of the most prevalent phytosterols which have been recorded in ancient medicinal history for its use in the treatment of many chronic diseases, especially cancer. The modulations of mitogen-activated protein kinases' (MAPKs') play a crucial role in the development of human renal cell carcinoma. OBJECTIVE: The aim of the current study is to evaluate the antigenotoxic and anticancer role of β-sitosterol against renal carcinogen...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28213110/effect-of-chinese-herbal-medicine-on-stroke-patients-with-type-2-diabetes
#15
Fuu-Jen Tsai, Tsung-Jung Ho, Chi-Fung Cheng, Xiang Liu, Hsinyi Tsang, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Ju-Pi Li, Cheng-Wen Lin, Jaung-Geng Lin, Jung-Chun Lin, Chih-Chien Lin, Wen-Miin Liang, Ying-Ju Lin
ETHNOPHARMACOLOGICAL RELEVANCE: Complications of type 2 diabetes (T2D) include stroke, which is a cerebrovascular disturbance characterized by reduced blood flow in the brain, leading to death or physical disability. Chinese herbal medicine (CHM) has been widely used in ancient China for the treatment of diabetes and stroke by supplementing Qi and activating blood circulation. AIM OF THE STUDY: This study aimed to investigate the frequencies and patterns of CHM treatment for stroke patients with T2D and the outcomes of long-term use in Taiwan...
March 22, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28212301/the-phytocomplex-from-fucus-vesiculosus-and-ascophyllum-nodosum-controls-postprandial-plasma-glucose-levels-an-in-vitro-and-in-vivo-study-in-a-mouse-model-of-nash
#16
Daniela Gabbia, Stefano Dall'Acqua, Iole Maria Di Gangi, Sara Bogialli, Valentina Caputi, Laura Albertoni, Ilaria Marsilio, Nicola Paccagnella, Maria Carrara, Maria Cecilia Giron, Sara De Martin
Edible seaweeds have been consumed by Asian coastal communities since ancient times. Fucus vesiculosus and Ascophyllum nodosum extracts have been traditionally used for the treatment of obesity and several gastrointestinal diseases. We evaluated the ability of extracts obtained from these algae to inhibit the digestive enzymes α-amylase and α-glucosidase in vitro, and control postprandial plasma glucose levels in a mouse model of non-alcoholic steatohepatitis (NASH); a liver disease often preceding the development of Type 2 diabetes (T2DM)...
February 15, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28194329/understanding-breast-cancer-the-long-and-winding-road
#17
REVIEW
Kiven Erique Lukong
BACKGROUND: Despite a remarkable increase in the depth of our understanding and management of breast cancer in the past 50 years, the disease is still a major public health problem worldwide and poses significant challenges. The palpability of breast tumors has facilitated diagnosis and documentation since ancient times. The earliest descriptions of breast cancer date back to around 3500 BCE. For centuries to follow, theories by Hippocrates (460 BCE) and Galen (200 CE), attributing the cause of breast cancer to an "excess of black bile" and treatment options including the use of opium and castor oil, prevailed...
June 2017: BBA Clinical
https://www.readbyqxmd.com/read/28182027/critical-review-of-rasaratna-samuccaya-a-comprehensive-treatise-of-indian-alchemy
#18
REVIEW
Dhirajsingh Sumersingh Rajput, Rohit Gokarn, Chandrashekhar Y Jagtap, R Galib, B J Patgiri, P K Prajapati
Rasaratna Samuccaya (RRS) a 13(th) century C.E. alchemical treatise, authored by Vāgbhaṭa, is a useful compilation related to preparation and properties of drugs of mineral and metallic origin. This text throws light on the state of Indian expertise in the field of alchemy regarding the extraction, purification, conversion of metals/minerals into therapeutically suitable forms, various instruments developed for alchemical purposes and treatment of numerous diseases by using herbo-mineral preparations. The present work is an attempt to summarize the key features of RRS to highlight its utility and contribution in the development of Indian alchemy...
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28165442/antimicrobial-efficacy-of-probiotic-containing-toothpastes-an-in-vitro-evaluation
#19
Miro Klarić, Vjekoslav Mandić, Sanjin Lovrić, Martina Krešić Ćorić, Nikolina Zovko
Most people have heard of the placebo effect, while relatively few have heard of nocebo, even within the circles of medical staff. Placebo effect means positive results by treatment via pharmacological inert substances. In contrast to placebo, by nocebo effect, due to negative beliefs and expectations, opposite results are achieved. Said in a more formal manner, what a sick person expects, unfortunately, he/she most often gets. It is a fact that a high number of medical staff is still uninterested in placebo and nocebo effects, although they would benefit from them...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28128718/prehispanic-functional-foods-and-nutraceuticals-in-the-treatment-of-dyslipidemia-associated-to-cardiovascular-disease-a-mini-review
#20
Alejandro Ríos-Hoyo, Alejandra Romo-Araiza, Marcos Meneses-Mayo, Gabriela Guttiérrez-Salmeán
Dyslipidemia is an important modifi able risk factor for cardiovascular and metabolic diseases, which are responsible for a large number of mortality and disability cases around the globe. Different strategies have been used within the treatment of dyslipidemia, including lifestyle modifi cations, pharmacologic therapy, as well as functional foods and nutraceuticals. Functional foods have been used worldwide since ancient times, particularly, the prehispanic civilizations utilized several as medicinal foods...
January 27, 2017: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
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