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https://www.readbyqxmd.com/read/27928544/vitiligo-treatment-in-ancient-iranian-medicine
#1
Mohammad Pourmand, Mohammad Asgharzadeh, Jalil Rashedi, Behroz Mahdavi Poor
No abstract text is available yet for this article.
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27927244/wuzi-yanzong-pill-a-chinese-polyherbal-formula-alleviates-testicular-damage-in-mice-induced-by-ionizing-radiation
#2
Hai-Jie Ji, Dong-Mei Wang, Yu-Peng Wu, Yan-Yan Niu, Li-Li Jia, Bi-Wang Liu, Qian-Jin Feng, Ma-Li Feng
BACKGROUND: Chinese medicine Wuzi Yanzong pill (WZYZP) was firstly documented in ancient Chinese medical works "She Sheng Zhong Miao Fang" by Shi-Che Zhang in 1550 AD. The traditional herbal formula is widely used in treating nephrasthenia lumbago, prospermia, erectile dysfunction and male sterility. The present study was to explore the effects of WZYZP on ionizing irradiation-induced testicular damage in mice. METHODS: The pelvic region of male mice was exposed to X-rays for inducing testicular damage...
December 7, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27924825/an-integrated-strategy-for-global-qualitative-and-quantitative-profiling-of-traditional-chinese-medicine-formulas-baoyuan-decoction-as-a-case
#3
Xiaoli Ma, Xiaoyu Guo, Yuelin Song, Lirui Qiao, Wenguang Wang, Mingbo Zhao, Pengfei Tu, Yong Jiang
Clarification of the chemical composition of traditional Chinese medicine formulas (TCMFs) is a challenge due to the variety of structures and the complexity of plant matrices. Herein, an integrated strategy was developed by hyphenating ultra-performance liquid chromatography (UPLC), quadrupole time-of-flight (Q-TOF), hybrid triple quadrupole-linear ion trap mass spectrometry (Qtrap-MS), and the novel post-acquisition data processing software UNIFI to achieve automatic, rapid, accurate, and comprehensive qualitative and quantitative analysis of the chemical components in TCMFs...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27920719/bile-acids-in-neurodegenerative-disorders
#4
REVIEW
Hayley D Ackerman, Glenn S Gerhard
Bile acids, a structurally related group of molecules derived from cholesterol, have a long history as therapeutic agents in medicine, from treatment for primarily ocular diseases in ancient Chinese medicine to modern day use as approved drugs for certain liver diseases. Despite evidence supporting a neuroprotective role in a diverse spectrum of age-related neurodegenerative disorders, including several small pilot clinical trials, little is known about their molecular mechanisms or their physiological roles in the nervous system...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27908257/ginkgo-biloba-as-an-alternative-medicine-in-the-treatment-of-anxiety-in-dementia-and-other-psychiatric-disorders
#5
Sandeep Kumar Singh, George E Barreto, Gjumrakch Aliev, Valentina Echeverria
BACKGROUND: Mental disorders are the most common health problems in the worldwide population. Current medicines against these conditions have undesired side effects or limited effectiveness. These disadvantageous pharmacological and therapeutic characteristics provoke a low adherence to treatment in an important percentage of patients with mental disorders. Since ancient times, ethnically different groups have been using plants extracts as medicines for the treatment of mental conditions including dementia, depression and anxiety disorders...
December 1, 2016: Current Drug Metabolism
https://www.readbyqxmd.com/read/27900309/from-loose-body-to-osteochondritis-dissecans-a-historical-account-of-disease-definition
#6
Vittorio Tarabella, Giuseppe Filardo, Berardo DI Matteo, Luca Andriolo, Patrizia Tomba, Anna Viganò, Maurilio Marcacci
Osteochondritis dissecans (OCD) is a rare yet fascinating disease affecting young, active patients. It remains a 'mysterious disease' whose etiopathology, still unclear, is the subject of ongoing studies aiming improving the knowledge of this condition and, therefore, treatment options, too. Even though the first descriptions of intra-articular loose bodies date back to very ancient times, it is only relatively recently that, thanks to the contribution of some very eminent physicians, it became recognized as a specific orthopaedic condition...
July 2016: Joints
https://www.readbyqxmd.com/read/27894990/microevolutionary-analyses-of-pythium-insidiosum-isolates-of-brazil-and-thailand-based-on-exo-1-3-%C3%AE-glucanase-gene
#7
Tatiana Corrêa Ribeiro, Carla Weiblen, Maria Isabel de Azevedo, Sônia de Avila Botton, Lizandra Jaqueline Robe, Daniela Isabel Brayer Pereira, Danieli Urach Monteiro, Douglas Miotto Lorensetti, Janio Morais Santurio
Pythium insidiosum is an important oomycete due to its ability to infect humans and animals. It causes pythiosis, a disease of difficult treatment that occurs more frequently in humans in Thailand and in horses in Brazil. Since cell-wall components are frequently related to host shifts, we decided here to use sequences from the exo-1.3-β-glucanase gene (exo1), which encodes an immunodominant protein putatively involved in cell wall remodeling, to investigate the microevolutionary relationships of Brazilian and Thai isolates of P...
November 25, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27892584/a-short-history-of-phototherapy-vitamin-d-and-skin-disease
#8
Paul Jarrett, Robert Scragg
The earliest record between sun exposure and skin disease goes back five millennia to the ancient Egyptians. The modern scientific era of medical light therapy and skin diseases started in 1877 when Downs and Blunt reported that exposure to light inhibited fungal growth in test tubes. Continuing research generated a growing medical interest in the potential the effects of light to treat and cure skin diseases considered as parasitic. This culminated in the awarding of the 1903 Nobel Prize in Medicine to Niels Finsen for his pioneering work showing that light could successfully treat cutaneous mycobacterium tuberculosis (lupus vulgaris), a disfiguring disorder common at the time...
November 28, 2016: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/27891329/effects-of-lead-in-various-preparatory-stages-of-nagabhasma-on-function-and-histopathology-of-cornu-ammonis-of-hippocampus
#9
Lydia S Quadros, Hemalatha Bangera, Sushma R Kotian, Kumar M R Bhat
INTRODUCTION: Heavy metals are frequently used in the preparations of traditional/folk medicines. One such preparation in Ayurveda is Nagabhasma, in which lead is the main ingredient. Lead is non-essential element to the human body and is known toxic substance to many organ systems. However, it is claimed that, the highly toxic metallic lead will be converted into health beneficial organo-metallic compound when raw lead is subjected to various traditional methods of purification during preparation as mentioned in the ancient medicinal system...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27889979/-ancient-medical-treatments-for-liver-disease
#10
Júlia Katona, Hedvig Győry, Anna Blázovics
No abstract text is available yet for this article.
November 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27886147/emerging-phytochemicals-for-the-prevention-and-treatment-of-head-and-neck-cancer
#11
REVIEW
Santosh K Katiyar
Despite the development of more advanced medical therapies, cancer management remains a problem. Head and neck squamous cell carcinoma (HNSCC) is a particularly challenging malignancy and requires more effective treatment strategies and a reduction in the debilitating morbidities associated with the therapies. Phytochemicals have long been used in ancient systems of medicine, and non-toxic phytochemicals are being considered as new options for the effective management of cancer. Here, we discuss the growth inhibitory and anti-cell migratory actions of proanthocyanidins from grape seeds (GSPs), polyphenols in green tea and honokiol, derived from the Magnolia species...
November 24, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27869738/plants-producing-ribosome-inactivating-proteins-in-traditional-medicine
#12
REVIEW
Letizia Polito, Massimo Bortolotti, Stefania Maiello, Maria Giulia Battelli, Andrea Bolognesi
Ribosome-inactivating proteins (RIPs) are enzymes that deadenylate nucleic acids and are broadly distributed in the plant kingdom. Many plants that contain RIPs are listed in the pharmacopoeias of folk medicine all over the world, mostly because of their toxicity. This review analyses the position occupied in traditional medicine by plants from which RIPs have been isolated. The overview starts from the antique age of the Mediterranean area with ancient Egypt, followed by the Greek and Roman classic period...
November 18, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27865509/effect-of-incremental-amounts-of-camelina-oil-on-milk-fatty-acid-composition-in-lactating-cows-fed-diets-based-on-a-mixture-of-grass-and-red-clover-silage-and-concentrates-containing-camelina-expeller
#13
A Halmemies-Beauchet-Filleau, K J Shingfield, I Simpura, T Kokkonen, S Jaakkola, V Toivonen, A Vanhatalo
Camelina is an ancient oilseed crop that produces an oil rich in cis-9,cis-12 18:2 (linoleic acid, LA) and cis-9,cis-12,cis-15 18:3 (α-linolenic acid, ALA); however, reports on the use of camelina oil (CO) for ruminants are limited. The present study investigated the effects of incremental CO supplementation on animal performance, milk fatty acid (FA) composition, and milk sensory quality. Eight Finnish Ayrshire cows (91 d in milk) were used in replicated 4 × 4 Latin squares with 21-d periods. Treatments comprised 4 concentrates (12 kg/d on an air-dry basis) based on cereals and camelina expeller containing 0 (control), 2, 4, or 6% CO on an air-dry basis...
November 16, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27837575/dreams-in-ancient-greek-medicine
#14
K Laios, M M Moschos, E Koukaki, E Vasilopoulos, M Karamanou, M-I Kontaxaki, G Androutsos
Dreams preoccupied the Greek and Roman world in antiquity, therefore they had a prominent role in social, philosophical, religious, historical and political life of those times. They were considered as omens and prophetic signs of future events in private and public life, and that was particularly accentuated when elements of actions which took place in the plot of dreams were associated directly or indirectly with real events. This is why it was important to use them in divination, and helped the growth of superstition and folklore believes...
July 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/27830869/atlas-occipitalization-associated-with-other-anomalies-in-a-16th-century-skeleton-from-sardinia-italy
#15
Valentina Giuffra, Andrea Montella, Marco Milanese, Eugenia Tognotti, Davide Caramella, Pasquale Bandiera
Archaeological excavations carried out in the plague cemetery of 16th century Alghero (Sardinia) brought to light the skeleton of a male aged 35-45 years, showing anomalies of the atlas. A macroscopic and radiological study has been carried out. The first cervical vertebra is fused with the skull base, resulting in an occipitalization of the atlas. Absence of the costal element of the left foramen trasversarium, resulting in an open anterior foramen trasversarium, and posterior arch defect are also observed...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27825178/ruscus-genus-a-rich-source-of-bioactive-steroidal-saponins
#16
Milena Masullo, Cosimo Pizza, Sonia Piacente
The genus Ruscus (Asparagaceae family) is native to the Mediterranean, Southern and Western Europe and is represented by perennial, rhizomatous, and evergreen shrubs. Among the approximately seven species spread throughout Europe up to Iran, Ruscus aculeatus L. (butcher's broom) is the most widely distributed and appreciated. This review provides an overview of the traditional use of Ruscus spp., the current knowledge of the chemistry of this genus, and the pharmacological studies carried out on Ruscus spp...
November 8, 2016: Planta Medica
https://www.readbyqxmd.com/read/27819488/microsomal-cytochrome-p450-as-a-target-for-drug-discovery-and-repurposing
#17
Ahmed A El-Sherbeni, Ayman O S El-Kadi
Cytochrome P450 (P450) enzymes are ancient electron-transfer-chain system of remarkable biological importance. Microsomal P450 enzymes are the P450 attached to endoplasmic reticulum, which, in humans, are critical for body's defences against xenobiotics by mediating their metabolism, and cell signalling by mediating arachidonic acid (AA) transformation to several potent bioactive molecules. Only recently, modulating P450-mediated AA metabolism has risen as a promising new drug target. The current review presents the therapeutic potential of finding effective, selective and safe treatments targeting P450-mediated AA metabolism, and the several approaches that have been used to find these treatments; among which, our focus was on modulators of P450 activities...
November 7, 2016: Drug Metabolism Reviews
https://www.readbyqxmd.com/read/27815315/inactivation-of-the-type-i-interferon-pathway-reveals-long-double-stranded-rna-mediated-rna-interference-in-mammalian-cells
#18
Pierre V Maillard, Annemarthe G Van der Veen, Safia Deddouche-Grass, Neil C Rogers, Andres Merits, Caetano Reis E Sousa
RNA interference (RNAi) elicited by long double-stranded (ds) or base-paired viral RNA constitutes the major mechanism of antiviral defence in plants and invertebrates. In contrast, it is controversial whether it acts in chordates. Rather, in vertebrates, viral RNAs induce a distinct defence system known as the interferon (IFN) response. Here, we tested the possibility that the IFN response masks or inhibits antiviral RNAi in mammalian cells. Consistent with that notion, we find that sequence-specific gene silencing can be triggered by long dsRNAs in differentiated mouse cells rendered deficient in components of the IFN pathway...
December 1, 2016: EMBO Journal
https://www.readbyqxmd.com/read/27807716/the-contribution-of-intellectuals-to-the-history-of-traumatology-during-the-renaissance-treatment-of-femoral-fracture-through-fran%C3%A3-ois-rabelais-glossocomion
#19
REVIEW
Francesco Manzini, Claudio Manzini, Giancarlo Cesana, Michele Augusto Riva
During the Middle Ages and the Renaissance, intellectuals often included clinical cases and medical descriptions in their literary works. These authors appeared to be more interested in internal and infectious diseases rather than in musculoskeletal disorders and orthopaedics. François Rabelais (1490-1553) was one of the most renowned humanists and philologists of the sixteenth century. He was also a physician with an interest in translating ancient texts of medical authors. Rabelais rediscovered a device for treating femoral fracture originally described by the Roman physician Galen and named as glossocomion...
November 2, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27803747/multi-drug-resistant-tuberculous-spondylitis-a-review-of-the-literature
#20
REVIEW
Quratulain Fatima Kizilbash, Barbara Joyce Seaworth
While tuberculous vertebral osteomyelitis is an ancient scourge, multi-drug resistant-tuberculosis (MDR-TB) is a modern major public health concern. The objective of this study was to review and summarize the data available on MDR-TB spondylitis. An extensive search of the PubMed database was conducted for articles in English relevant to MDR-TB spondylitis by December 2015. Tuberculous spondylitis accounts for 0.5-1% of all TB cases, and it is estimated that there are probably 5000 MDR-TB spondylitis cases each year worldwide...
October 2016: Annals of Thoracic Medicine
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