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https://www.readbyqxmd.com/read/28933100/-decipherment-of-ancient-literature-about-danshen
#1
Ai-Ping Deng, Lan-Ping Guo, Zhi-Lai Zhan, Lu-Qi Huang
Danshen has a long history in China as a commen traditional Chinese medicine, but many other members of the Salvia family is also used as Danshen in particular regions. The name of Danshen were analyzed according to the color, efficacity and etc. To investigate the real origin of Danshen, the stalk, leaf, flower and radix in chronicle and pictures of ancient literature were deciphered. It showed that in the past dynasties, Salvia miltiorrhiza was the most likely plant used as Danshen. The rigin and quality evaluation of Danshen were also summerized, provided new insight and proof for the development and utilization of Danshen...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28933099/-herbal-textual-research-of-common-mongolian-medicine-du-ge-mo-nong
#2
Jie Xi, Hua-Rong Zhong, Wucharila-Tu, Buhe Bater, Hui-Hu Li, Guo-Yue Zhong
This study is aimed to provide the source for clinical medication by clarifing the common base of Mongolia medicinal materials "Du Ge Mo Nong". In this paper literature research and plant taxonomy method were adopted combined with investigation of the markets and clinical use status to clarify the origin of common traditional Mongolian medicine "Du Ge Mo Nong". The results showed that the Mongolian medicine "Du Ge Mo Nong" and Tibetan medicine "Du Mu Niu" were the same crude drug and originated from the seeds of Holarrhena antidysenteriaca of family Apocynaceae in earliest time...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28932197/antiplasmodial-activity-and-toxicological-assessment-of-curcumin-plga-encapsulated-nanoparticles
#3
Zulaikha A Busari, Kabiru A Dauda, Olajumoke A Morenikeji, Funmilayo Afolayan, Oyetunde T Oyeyemi, Jairam Meena, Debasis Sahu, Amulya K Panda
Curcumin is a polyphenolic pigment isolated from the rhizomes of Curcuma longa (turmeric), a medicinal plant widely used in the ancient Indian and Chinese medicine. The antiplasmodial activity of curcumin is often hampered by its fast metabolism and poor water solubility, thus its incorporation into a delivery system could circumvent this problem. This study aimed to evaluate the in vivo antiplasmodial activity and the toxicity assessment of curcumin incorporated into poly (lactic-co-glycolic) acid (PLGA) nanoparticles...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28928512/determination-of-antioxidant-activity-of-hibiscus-sabdariffa-and-croton-caudatus-in-saccharomyces-cerevisiae-model-system
#4
Pattnaik Subhaswaraj, M Sowmya, V Bhavana, Madhu Dyavaiah, Busi Siddhardha
From ancient times, plants and plant derived products are exploited as a prominent source of folkloric medicines with tremendous therapeutic potential for an array of health disorders. In the present study, ethanolic leaf extract of Hibiscus sabdariffa and Croton caudatus were evaluated for free radical scavenging activity in Saccharomyces cerevisiae model system. H. sabdariffa and C. caudatus showed tremendous DPPH free radical scavenging potential with an IC50 value of 184.88 and 305.39 µg/mL respectively at a concentration of 500 µg/mL...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28899513/mechanisms-underlying-the-wound-healing-potential-of-propolis-based-on-its-in-vitro-antioxidant-activity
#5
Xue-Ping Cao, Yi-Fan Chen, Jiang-Lin Zhang, Meng-Meng You, Kai Wang, Fu-Liang Hu
BACKGROUND: Propolis is a resinous substance collected by honeybees, Apis mellifera, from various plant sources. Having various pharmacological and biological activities, it has been used in folk medicine and complementary therapies since ancient times. PURPOSE: To evaluate the effects and underlying mechanism of the protective effects of the ethanol extract of Chinese propolis (EECP) on L929 cells injured by hydrogen peroxide (H2O2). STUDY DESIGN: The wound healing activities of EECP in L929 cells with H2O2-induced damage were investigated...
October 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28884602/enhancement-of-anticancer-activity-by-silibinin-and-paclitaxel-combination-on-the-ovarian-cancer
#6
Fatima Pashaei-Asl, Roghiyeh Pashaei-Asl, Khodadad Khodadadi, Abolfazl Akbarzadeh, Esmaeil Ebrahimie, Maryam Pashaiasl
BACKGROUND: Ovarian carcinoma is the most lethal cancer among all gynaecological malignancies. One of the most chemotherapy drugs used for ovarian cancer is paclitaxel which induces apoptosis. Paclitaxel has been used for many years. Similar to the most cancers this responds to chemotherapy initially but in a long run, drug resistance happens which fails the treatment procedure. Combination of chemotherapy drugs has been suggested to deal with this issue. Silibinin, a plant extraction, has been used from ancient time in traditional medicine and identified to have powerful antioxidant activity...
September 8, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28876177/ancient-indian-concepts-about-phenomenology-biology-and-therapeutics-of-epilepsy
#7
Ravindra Arya
This article discusses etiology, pathogenesis, symptoms, and treatment of epilepsy, as described in Charaka Samhitā (translation: Charaka's Compendium) and Sushruta Samhitā, the two core texts of Ayurveda, an ancient system of medicine. Ayurveda emphasized amnesia and loss of consciousness as core features of epileptic seizures (Sanskrit: apasmar; translation: apa negation, smaran memory) and recognized that seizures occur due to a disturbance in brain function or flow of "humors" to the brain. Semiology of various seizure types was well described...
September 6, 2017: Journal of the History of the Neurosciences
https://www.readbyqxmd.com/read/28860989/ethnopharmacological-approaches-for-therapy-of-jaundice-part-i
#8
REVIEW
Devesh Tewari, Andrei Mocan, Emil D Parvanov, Archana N Sah, Seyed M Nabavi, Lukasz Huminiecki, Zheng Feei Ma, Yeong Yeh Lee, Jarosław O Horbańczuk, Atanas G Atanasov
Jaundice is a very common symptom especially in the developing countries. It is associated with several hepatic diseases which are still major causes of death. There are many different approaches to jaundice treatment and the growing number of ethnomedicinal studies shows the plant pharmacology as very promising direction. Many medicinal plants are used for the treatment of jaundice, however a comprehensive review on this subject has not been published. The use of medicinal plants in drug discovery is highly emphasized (based on their traditional and safe uses in different folk medicine systems from ancient times)...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28855098/the-bioelectric-code-an-ancient-computational-medium-for-dynamic-control-of-growth-and-form
#9
REVIEW
Michael Levin, Christopher J Martyniuk
What determines large-scale anatomy? DNA does not directly specify geometrical arrangements of tissues and organs, and a process of encoding and decoding for morphogenesis is required. Moreover, many species can regenerate and remodel their structure despite drastic injury. The ability to obtain the correct target morphology from a diversity of initial conditions reveals that the morphogenetic code implements a rich system of pattern-homeostatic processes. Here, we describe an important mechanism by which cellular networks implement pattern regulation and plasticity: bioelectricity...
August 27, 2017: Bio Systems
https://www.readbyqxmd.com/read/28853524/-cerebral-palsy-at-the-age-of-modern-obstetrics-ancient-beliefs-versus-solid-facts
#10
Shali Mazaki-Tovi
For many decades the conventional wisdom was that the sole etiology for cerebral palsy is difficult delivery. The adverse outcome associated with cerebral palsy was intuitively related to complications during labor. The blame, unjustifiably and recklessly, was placed on devoted physicians and midwifes. This wrongful accusation, that one may describe as "scientific blood libel" is unprecedented in medicine. In his article, Professor Blickstein scrupulously revises the scientific evidence connecting birth asphyxia and cerebral palsy and refutes the common belief that the only cause for cerebral palsy is complicated delivery...
August 2017: Harefuah
https://www.readbyqxmd.com/read/28852418/danggui-buxue-tang-a-simple-chinese-formula-containing-astragali-radix-and-angelicae-sinensis-radix-stimulates-the-expressions-of-neurotrophic-factors-in-cultured-sh-sy5y-cells
#11
Amy G W Gong, Huai Y Wang, Tina T X Dong, Karl W K Tsim, Y Z Zheng
BACKGROUND: Danggui Buxue Tang (DBT), a phytoestrogen-enriched Chinese herbal formula, serves as dietary supplement in stimulating the "Blood" functions of menopausal women. In traditional Chinese medicine (TCM) theory, "Blood" has a strong relationship with brain activities. Previous studies supported that some ingredients of DBT possessed neuronal beneficial functions. Therefore, the neurotrophic function and the mechanistic action of DBT were systematically evaluated in cultured human neuroblastoma SH-SY5Y cells...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/28840706/-evolution-and-transition-of-source-of-patrinia-herba-and-patrinia-radix
#12
Ying-Long Xiang, Gui-Lin Mei, Han Luo, Wen-Tao Fang, Hua-Sheng Peng, Cheng-Wu Feng, Qing-Shan Yang, Xiang-Yu Li, Yan-Peng Zhang
Both Patrinia Herba and Patrinia Radix are traditional Chinese herbal medicines. The herbal source and medicinal part of them are confusing in the herbal medicine market of China. To explore the evolution and transition of the herbal source and medicinal part of Patrinia Herba and Patrinia Radix, this paper systematically summarizes the record of the herbal source and medicinal part of them in ancient classics of herbal medicine in China. According to the findings, before Ming Dynasty, Patrinia Herba originated from the radix of the plants with yellow flowers of Patrinia...
July 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28834122/bitter-substances-from-plants-used-in-traditional-chinese-medicine-exert-biased-activation-of-human-bitter-taste-receptors
#13
Maik Behrens, Ming Gu, Shengjie Fan, Cheng Huang, Wolfgang Meyerhof
The number and variety of bitter compounds originating from plants is vast. Whereas some bitter chemicals are toxic and should not be ingested, other compounds exhibit health beneficial effects, which is manifest in the cross-cultural believe that the bitterness of medicine is correlated with the desired medicinal activity. The bitter taste receptors in the oral cavity serve as sensors for bitter compounds and, since they are expressed in numerous extraoral tissues throughout the body, may also be responsible for some physiological effects exerted by bitter compounds...
August 21, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28833680/toxicological-effects-of-glycyrrhiza-glabra-licorice-a-review
#14
REVIEW
Somayeh Nazari, Maryam Rameshrad, Hossein Hosseinzadeh
Licorice (Glycyrrhiza glabra) has been considered as an herbal drug since ancient time. Nowadays, it is a well-known spice that possesses worth pharmacological effects. However, some relevant articles have revealed negative impacts of licorice in health. By considering the great wishes in using herbal medicine, it is important to show adverse effects of herbal medicine in health. At present, there are misunderstandings toward the safety of herbal medicines. Herein, we gathered scientific research projects on the toxicity effects of licorice and glycyrrhizin to highlight their safety...
August 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28832953/colchicine-an-ancient-drug-with-novel-applications
#15
REVIEW
B Dasgeb, D Kornreich, K McGuinn, L Okon, I Brownell, D L Sackett
Colchicine is a historic treatment for gout that has been used for more than a millennium. It is the treatment of choice for Familial Mediterranean Fever and its associated complication, amyloidosis. The 2009 FDA approval of colchicine as a new drug had research consequences. Recent investigations utilizing large cohorts of gout patients who have been taking colchicine for years have demonstrated novel applications within oncology, immunology, cardiology and dermatology. Some emerging dermatologic uses include the treatment of epidermolysis bullosa acquisita, leukocytoclastic vasculitis, aphthous stomatitis and others...
August 18, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28830818/review-of-anti-inflammatory-immune-modulatory-and-wound-healing-properties-of-molluscs
#16
REVIEW
Tarek B Ahmad, Lei Liu, Michael Kotiw, Kirsten Benkendorff
ETHNOPHARMACOLOGICAL RELEVANCE: This review focuses on traditional and contemporary anti-inflammatory uses of mollusc-derived products summarising all the in vitro, in vivo and human clinical trials that have tested the anti-inflammatory activity of molluscan natural products. Inflammatory conditions, burns and wounds have been an ongoing concern for human health since the early era of civilisation. Many texts from ancient medicine have recorded the symptoms, signs and treatments for these conditions...
August 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28822168/-import-and-export-of-licorice-and-its-products-in-china
#17
Shuai Ma, Nuo Wang, Guang Yang, Ling Que
Licorice is an important harmonic drug which has been widely used in traditional Chinese medicine since ancient times. However, with the increasing demand of industrial production, the licorice resources in our country have been reduced rapidly and we have to import licorice resources from Kazakhstan and Uzbekistan consequently. In order to find out the trade flow of licorice resources and evaluate the status of Chinese licorice in the world trade, the trade situation of licorice and its products from 2011 to 2015 May in Chinese customs was investigated and analyzed in this paper...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28818559/-to-boldly-go-where-no-one-has-gone-before
#18
Keith W Kelley
Americans are suffering from a culture of taking pills. Six out of ten Americans utilize at least one prescription drug, and more than one in ten use five or more prescription medicines. Although this torrent of taking pills is already high, drug use in the USA has not yet crested. Prescription drugs have specific targets, but often they adversely affect other tissues and organs. In keeping with the mission of the recently named National Center for Complementary and Integrative Health (NCCIH), Brain, Behavior, and Immunity searches for the underlying cause and potential efficacy of both drug and non-drug interventions...
August 14, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28810347/-history-of-world-neurosurgery
#19
X Wang
In 5000 BC, South American tribes digged the bones in the living head to seek ways to communicate with the gods, which was primitive trephination and may be the first neurosurgical behavior. In 2600 BC, Imhotep in ancient Egypt took the brain out of the head from the nose, for a better preserve of the mummy, which was a prototype of modern transsphenoidal surgery. And the development of anatomy in ancient Greek laid a solid foundation for neurosurgery. From 500 to 1500 AD, the rise of religion and the occurrence of war, prompted a large number of craniocerebral trauma, which contributed greatly to the early development of neurosurgery as a distinct specialty...
May 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28808784/the-history-of-optic-chiasm-from-antiquity-to-the-twentieth-century
#20
REVIEW
Claudia Florida Costea, Şerban Turliuc, Cătălin Buzdugă, Andrei Ionuţ Cucu, Gabriela Florenţa Dumitrescu, Anca Sava, Mihaela Dana Turliuc
PURPOSE: The optic chiasm is an essential structure located at the skull base that stirred over time the curiosity of anatomists, who became more and more interested in its structure and function. Through centuries, the optic chiasm was viewed as a vessel crossing, a way of transporting tears secreted by the brain to the eye, integrating images, or responsible for coordinated eye movements. The paper aims to overview the history of understanding the optic chiasm from the beginnings of antiquity to the twentieth century...
August 14, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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