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https://www.readbyqxmd.com/read/29793201/positive-effects-of-an-oil-adjuvant-on-efficacy-dissipation-and-safety-of-pyrimethanil-and-boscalid-on-greenhouse-strawberry
#1
Zhiwei Wang, Xinquan Wang, Tao Cang, Xueping Zhao, Shenggan Wu, Peipei Qi, Xiangyun Wang, Xiahong Xu, Qiang Wang
Methylated vegetable oil adjuvants can enhance initial deposition and decrease the required dosages of pesticides sprayed on plants, so an oil adjuvant mixed with fungicides were used to prevent and control gray mold in greenhouse strawberry. As the persistence and dietary exposure risks from fungicides on strawberries after using adjuvants have not been assessed, the efficacy, dissipation and safety of pyrimethanil and boscalid in the presence and absence of a methylated vegetable oil adjuvant were evaluated...
May 21, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29793181/exogenously-applied-spermidine-alleviates-photosynthetic-inhibition-under-drought-stress-in-maize-zea-mays-l-seedlings-associated-with-changes-in-endogenous-polyamines-and-phytohormones
#2
Lijie Li, Wanrong Gu, Jing Li, Congfeng Li, Tenglong Xie, Danyang Qu, Yao Meng, Caifeng Li, Shi Wei
Drought stress (DS) is a major environmental factor limiting plant growth and crop productivity worldwide. It has been established that exogenous spermidine (Spd) stimulates plant tolerance to DS. The effects of exogenous Spd on plant growth, photosynthetic performance, and chloroplast ultrastructure as well as changes in endogenous polyamines (PAs) and phytohormones were investigate in DS-resistant (Xianyu 335) and DS-sensitive (Fenghe 1) maize seedlings under well-watered and DS treatments. Exogenous Spd alleviated the stress-induced reduction in growth, photosynthetic pigment content, photosynthesis rate (Pn ) and photochemical quenching (qP ) parameters, including the maximum photochemistry efficiency of photosystem II (PSII) (Fv /Fm ), PSII operating efficiency (ФPSII), and qP coefficient...
May 15, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29791883/relationship-between-modification-of-activated-sludge-wastewater-treatment-and-changes-in-antibiotic-resistance-of-bacteria
#3
Ewa Korzeniewska, Monika Harnisz
Biological treatment processes at wastewater treatment plants (WWTPs), which are the most common methods of sewage treatment, could cause selective elimination and/or changes in the proportions of phenotypes/genotypes within bacterial populations in effluent. Therefore, WWTPs based on activated sludge used in sewage treatment constitute an important reservoir of enteric bacteria which harbour potentially transferable resistance genes. Together with treated wastewater, these microorganisms can penetrate the soil, surface water, rural groundwater supplies and drinking water...
May 20, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29791314/analgesic-anti-inflammatory-and-anti-arthritic-properties-of-aqueous-and-methanolic-stem-bark-extracts-from-nauclea-pobeguinii-rubiacee-in-rats
#4
Mbiantcha Marius, Tsafack Eric Gonzal, Ateufack Gilbert, Nana Yousseu William, Bomba Tatsinkou Francis Désiré, Djuichou Nguemnang Stephanie Flore, Mbankou Ngassam Sorelle, Wego Kamgaing Marius Tresor
Background Nauclea pobeguinii is a plant species found in the centre region of Cameroon. The stem bark of this plant is traditionally used to ease pain and cure inflammation. Method This study was undertaken to evaluate the effects of doses 150 and 300 mg/kg of the aqueous and methanolic stem bark extracts from Nauclea pobeguinii on acute pain, acute and chronic inflammation induced by formalin and arthritis induced by zymosan A in rats. Oxidative stress parameters such as catalase, malondialdehyde and nitric oxide were measured in rats subjected to chronic inflammation...
May 23, 2018: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/29791008/the-pharmacology-pharmacokinetics-efficacy-and-adverse-events-associated-with-kava
#5
REVIEW
C Michael White
Kava is a plant with numerous kavapyrones that can induce pharmacologic effects and drug interactions through the cytochrome P450 and P-glycoprotein systems. Kava is used recreationally and for the treatment of anxiety. Clinical trials verify anxiolytic effects in excess of placebo, but the effects are not seen immediately and the optimal dose and dosing schedule needs to be determined. Clinical trials usually lasting for 4 weeks found generally good tolerability and safety; however, dermatologic, hepatologic, and cognitive adverse effects may occur...
May 23, 2018: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29790584/effects-of-psidium-guajava-leaf-extract-on-secretion-systems-of-gram-negative-enteropathogenic-bacteria
#6
Noboru Nakasone, Yasunori Ogura, Naomi Higa, Claudia Toma, Yukiko Koizumi, Giichi Takaesu, Toshihiko Suzuki, Tetsu Yamashiro
We screened a total of 672 plant-tissue extracts to search for phytochemicals that inhibit the function of the type III secretion system (T3SS) of enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC). Among candidates examined, we found that an extract from the leaves of Psidium guajava (guava) inhibited the secretion of the EspB protein from EPEC and EHEC without affecting bacterial growth. The guava extract (GE) also inhibited EPEC and EHEC from adhering to and injecting EspB protein into HEp-2 cells...
May 23, 2018: Microbiology and Immunology
https://www.readbyqxmd.com/read/29790547/melissa-officinalis-l-ethanolic-extract-inhibits-the-growth-of-a-lung-cancer-cell-line-by-interfering-with-the-cell-cycle-and-inducing-apoptosis
#7
D B Magalhães, I Castro, V Lopes-Rodrigues, J M Pereira, L Barros, I C F R Ferreira, C P R Xavier, M H Vasconcelos
Melissa officinalis is a plant from the family Lamiaceae, native in Europe particularly in the Mediterranean region. Given our interest in identifying extracts and compounds capable of inhibiting tumor cell growth, and given the antioxidant content and the high consumption of Melissa officinalis in Portugal, this study aimed to test the tumor cell growth inhibitory activity of five different extracts of this plant (aqueous, methanolic, ethanolic, hydromethanolic and hydroethanolic) in three human tumor cell lines: MCF-7, AGS and NCI-H460...
May 23, 2018: Food & Function
https://www.readbyqxmd.com/read/29789939/effects-of-heat-stress-in-the-leaf-mitotic-cell-cycle-and-chromosomes-of-four-wine-producing-grapevine-varieties
#8
Ana Carvalho, Fernanda Leal, Manuela Matos, José Lima-Brito
Grapevine varieties respond differentially to heat stress (HS). HS ultimately reduces the photosynthesis and respiratory performance. However, the HS effects in the leaf nuclei and mitotic cells of grapevine are barely known. This work intends to evaluate the HS effects in the leaf mitotic cell cycle and chromosomes of four wine-producing varieties: Touriga Franca (TF), Touriga Nacional (TN), Rabigato, and Viosinho. In vitro plants with 11 months were used in a stepwise acclimation and recovery (SAR) experimental setup comprising different phases: heat acclimation period (3 h-32 °C), extreme HS (1 h-42 °C), and two recovery periods (3 h-32 °C and 24 h-25 °C), and compared to control plants (maintained in vitro at 25 °C)...
May 22, 2018: Protoplasma
https://www.readbyqxmd.com/read/29789490/evaluation-of-lactic-acid-bacteria-on-the-inhibition-of-vibrio-parahaemolyticus-infection-and-its-application-to-food-systems
#9
Cheng-Chih Tsai, Yung-Hsien Hung, Lan-Chun Chou
This study tested the effect of lactic acid bacteria (LAB) inhibition on Vibrio parahaemolyticus BCRC (Bioresource Collection and Research Center) 10806 and BCRC 12865 in a food model. MTT [3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assays indicated that Caco-2 cells were not damaged after a two-hour treatment with lactic acid bacteria (LAB) and V. parahaemolyticus . The LAB cell culture and supernatant effectively inhibited the growth of V. parahaemolyticus in a food model. ELISA (Enzyme-linked immunosorbent assay) results indicated the significant inhibition of TNF-α; IL-1β; and IL-6; but Lactobacillus plantarum PM 222 and L...
May 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29789435/molecular-mechanisms-preventing-senescence-in-response-to-prolonged-darkness-in-a-desiccation-tolerant-plant
#10
Meriem Durgud, Saurabh Gupta, Ivan Ivanov, Amin Omidbakhshfard, Maria Benina, Saleh Alseekh, Nikola Staykov, Mareike Hauenstein, Paul Dijkwel, Stefan Hörtensteiner, Valentina Toneva, Yariv Brotman, Alisdair R Fernie, Bernd Mueller-Roeber, Tsanko Gechev
The desiccation-tolerant plant Haberlea rhodopensis can withstand months of darkness without any visible senescence. Here, we investigated the molecular mechanisms of this adaptation to prolonged (30 days) darkness and subsequent return to light. H. rhodopensis plants remained green and viable throughout the dark treatment. Transcriptomic analysis revealed that darkness regulated several transcription factor (TF) genes. Stress- and autophagy-related TFs such as ERF8, HSFA2b, RD26, TGA1, and WRKY33 were upregulated, while chloroplast- and flowering-related TFs such as ATH1, COL2, COL4, RL1, and PTAC7 were repressed...
May 22, 2018: Plant Physiology
https://www.readbyqxmd.com/read/29788981/safety-of-pazopanib-and-sunitinib-in-treatment-naive-patients-with-metastatic-renal-cell-carcinoma-asian-versus-non-asian-subgroup-analysis-of-the-comparz-trial
#11
Jun Guo, Jie Jin, Mototsugu Oya, Hirotsugu Uemura, Shunji Takahashi, Katsunori Tatsugami, Sun Young Rha, Jae-Lyun Lee, Jinsoo Chung, Ho Yeong Lim, Hsi Chin Wu, Yen Hwa Chang, Arun Azad, Ian D Davis, Marlene J Carrasco-Alfonso, Bhupinder Nanua, Jackie Han, Qasim Ahmad, Robert Motzer
BACKGROUND: The international, phase 3 COMPARZ study demonstrated that pazopanib and sunitinib have comparable efficacy as first-line therapy in patients with advanced renal cell carcinoma, but that safety and quality-of-life profiles favor pazopanib. Our report analyzed pazopanib and sunitinib safety in Asian and non-Asian subpopulations. METHODS: Patients were randomized 1:1 to receive pazopanib 800 mg once daily (continuous dosing) or sunitinib 50 mg once daily in 6-week cycles (4 weeks on, 2 weeks off)...
May 22, 2018: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/29788539/responses-of-primula-vulgaris-to-light-quality-in-the-maternal-and-germination-environments
#12
M Marin, C Blandino, G Laverack, P Toorop, A A Powell
In the model species Arabidopsis thaliana phytochromes mediate dormancy and germination responses to seasonal cues experienced during seed maturation on the maternal plants. However, the effect of the maternal light environment on seed germination in native wild species has not been studied well. This is particularly important given its practical application in the context of environmental restoration, when there can be marked changes in the canopy. Plants of Primula vulgaris were grown in the field over two vegetative seasons under four shading treatments from low to high ratio of red to far-red light (R:FR)...
May 22, 2018: Plant Biology
https://www.readbyqxmd.com/read/29788191/functional-characterization-of-why-wrky75-transcriptional-module-in-plant-response-to-cassava-bacterial-blight
#13
Wen Liu, Yu Yan, Hongqiu Zeng, Xiaolin Li, Yunxie Wei, Guoyin Liu, Chaozu He, Haitao Shi
Cassava is a major food crop in tropical areas, but its productivity and quality are seriously limited by cassava bacterial blight. So far, the key factors regulating cassava immune response remain elusive. In this study, we identified three cassava Whirly genes (MeWHYs) in cassava variety of South China 124 (SC124), and explored the possible roles and utilization of MeWHYs in cassava disease resistance. Gene expression analysis revealed that the transcripts of three MeWHYs were commonly regulated by the highly conserved N-terminal epitope of f lagellin (flg22) and Xanthomonas axonopodis pv...
May 19, 2018: Tree Physiology
https://www.readbyqxmd.com/read/29788186/nanoparticle-based-oral-drug-delivery-systems-targeting-the-colon-for-treatment-of-ulcerative-colitis
#14
Mingzhen Zhang, Didier Merlin
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery of orally administered drugs to the colon is highly desirable for the treatment of UC, as it improves their efficacy while reducing systemic toxicity. However, the targeting of oral drugs to the colon, which is located at the distal end of the gastrointestinal tract, is difficult due to physiological challenges, biochemical barriers, and environmental barriers, including those associated with mucus and epithelium...
May 18, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29788026/ragweed-pollen-allergy-burden-characteristics-and-management-of-an-imported-allergen-source-in-europe
#15
REVIEW
Kuan-Wei Chen, Laura Marusciac, Paul Tudor Tamas, Rudolf Valenta, Carmen Panaitescu
Ambrosia artemisiifolia, also known as common or short ragweed, is an invasive annual flowering herbaceous plant that has its origin in North America. Nowadays, ragweed can be found in many areas worldwide. Ragweed pollen is known for its high potential to cause type I allergic reactions in late summer and autumn and represents a major health problem in America and several countries in Europe. Climate change and urbanization, as well as long distance transport capacity, enhance the spread of ragweed pollen...
May 22, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29787969/efficacy-of-batch-mode-rotary-drum-composter-for-management-of-aquatic-weed-hydrilla-verticillata-l-f-royle
#16
Mayur Shirish Jain, Ajay S Kalamdhad
Invasive aquatic weed management is one of the biggest challenges in the field of solid waste management. Eichhornia crassipes, Pistia stratiotes and Hydrilla verticillata (L.f.) Royle pose some of the world's most noted aquatic weed problems. Previously reported studies on management of H. verticillata, a submersed aquatic plant, have shown that temporary removal, chemical treatment or biological control methods each have advantages and disadvantages. Removal programs that propose to compost harvested H. verticillata biomass may provide a novel technique to manage this issue...
May 19, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29786916/herbal-medicine-as-a-promising-therapeutic-approach-for-the-management-of-vascular-dementia-a-systematic-literature-review
#17
REVIEW
Adel Ghorani-Azam, Samaneh Sepahi, Elham Khodaverdi, Seyed Ahmad Mohajeri
Vascular dementia (VaD) generally refers to memory deficits and cognitive abnormalities that are resulted from vascular disease. In this study, we aimed to systematically review the literature wherein therapeutic effects of medicinal plants have been studied on VaD. A systematic literature search was performed in the PubMed, Scopus, Web of Science, Google Scholar, and other databases using VaD, and medicinal plants as key terms. No strict inclusion criteria were defined, and almost all clinical studies were included...
May 22, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29786751/inhibition-of-osteoclastogenesis-for-periprosthetic-osteolysis-therapy-through-the-suppression-of-p38-signaling-by-fraxetin
#18
Jia-Cheng Liao, Zhao-Xia Wei, Chang Zhao, Zhong-Ping Ma, Dao-Zhang Cai
Periprosthetic osteolysis belongs to osteolytic diseases, which often occur due to an imbalance between osteoclast and osteoblast number or activity. Fraxetin, a natural plant extract, inhibits osteoblast apoptosis and has therapeutic potential for treating osteolytic diseases. However, data pertaining to the effects of fraxetin on osteoclasts are limited. In the present study, it was demonstrated that the inhibition of osteoclastogenesis by fraxetin had an important role on the therapy of titanium particle‑induced osteolysis in vivo...
May 21, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29786651/clinical-efficacy-associated-with-enhanced-antioxidant-enzyme-activities-of-silver-nanoparticles-biosynthesized-using-moringa-oleifera-leaf-extract-against-cutaneous-leishmaniasis-in-a-murine-model-of-leishmania-major
#19
Manal El-Khadragy, Ebtesam M Alolayan, Dina M Metwally, Mohamed F Serag El-Din, Sara S Alobud, Nour I Alsultan, Sarah S Alsaif, Manal A Awad, Ahmed E Abdel Moneim
Leishmaniasis is one of the most significant vector-borne syndromes of individuals. This parasitic infection can be affected by many species of Leishmania, most of which are zoonotic. Natural products have made and are continuing to make important contributions to the search for new antileishmanial agents. The use of plants in the production assembly of silver nanoparticles has drawn attention because of its rapid, eco-friendly, non-pathogenic, economical protocol and provides a single step technique for the biosynthetic process...
May 22, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29786410/percutaneous-deep-venous-arterialization-in-patients-with-critical-limb-ischemia-a-technical-note
#20
Steven Kum, Eline Huizing, Michiel A Schreve, Çagdas Ünlü, Roberto Ferraresi, Lasitha B Samarakoon, Daniel A van den Heuvel
Critical limb ischemia (CLI) is the presentation of end stage peripheral arterial disease and typically presents with rest pain, ulceration and gangrene. The outcome of conservative treatment is poor and often leads to amputations. Arterial revascularization plays an important role in amputation prevention. Unfortunately, a significant percentage of CLI patients cannot be revascularized and subsequently end up with a palliative amputation. This has led to the need and exploration of new treatment options in this no option subgroup of CLI...
May 22, 2018: Journal of Cardiovascular Surgery
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