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Natural herbal medicine*

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https://www.readbyqxmd.com/read/29676114/-pharmacological-effect-of-combined-administration-of-natures-tastes-and-components-of-chinese-herbal-compounds
#1
REVIEW
Chun-Yan Lv, Shao-Wa Lv, Guo-Yu Li, Hai-Xue Kuang
The combined administration of traditional Chinese medicine (TCM) aims at comprehensive adjustment of body based on the theory of TCM and the theory of Chinese medicine property. The natures and tastes of TCM are the core of the theory of TCM property. The combined administration of natures and tastes of TCM is one of the important theories of prescription compatibility. The objective of study on the combined administration of natures and tastes of prescriptions according to symptoms of disease is to clarify the compatibility mechanism of prescriptions...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29674964/botanical-provenance-of-traditional-medicines-from-carpathian-mountains-at-the-ukrainian-polish-border
#2
REVIEW
Weronika Kozlowska, Charles Wagner, Erin M Moore, Adam Matkowski, Slavko Komarnytsky
Plants were an essential part of foraging for food and health, and for centuries remained the only medicines available to people from the remote mountain regions. Their correct botanical provenance is an essential basis for understanding the ethnic cultures, as well as for chemical identification of the novel bioactive molecules with therapeutic effects. This work describes the use of herbal medicines in the Beskid mountain ranges located south of Krakow and Lviv, two influential medieval centers of apothecary tradition in the region...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29673137/herb-induced-liver-injuries-in-developing-nations-an-update
#3
REVIEW
Cecilia Nwadiuto Amadi, Orish Ebere Orisakwe
The last few decades have seen a rise in the use of herbal supplements, natural products, and traditional medicines. However, there are growing concerns related to the safety and toxicities of these medicines. These herbal medicines are associated with complications such as liver damage with a high incidence of mortalities and morbidities. Clinical manifestations range from asymptomatic cases with abnormal liver functions tests to sudden and severe liver failure necessitating liver transplantation. This work aimed to review the etiology, risk factors, diagnosis, clinical manifestations and selected clinical case reports of herbal hepatotoxicity in developing nations...
April 17, 2018: Toxics
https://www.readbyqxmd.com/read/29668336/antiproliferative-effect-of-vine-stem-extract-from-spatholobus-suberectus-dunn-on-rat-c6-glioma-cells-through-regulation-of-ros-mitochondrial-depolarization-and-p21-protein-expression
#4
Hyungkuen Kim, Sun Shin Yi, Hak-Kyo Lee, Tae-Hwe Heo, Sang-Kyu Park, Hyun Sik Jun, Ki Duk Song, Sung-Jo Kim
The vine stem of Spatholobus suberectus Dunn (SS) is used as a traditional herbal medicine in China. Chinese herbal medicines are well known as natural bioactive compounds that can be used as new medicines, and their antioxidant and anticancer effects have also been reported. This study aimed to examine the anticancer effect of a high-pressure hot-water SS extract on rat C6 glioma cells. The SS extract effectively suppressed the viability and proliferation of C6 glioma cells through an antioxidant effect. Reactive oxygen species (ROS) levels in cancer cells are higher than that in normal cells...
April 18, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29628291/citri-reticulatae-pericarpium-chenpi-botany-ethnopharmacology-phytochemistry-and-pharmacology-of-a-frequently-used-traditional-chinese-medicine
#5
REVIEW
Xin Yu, Shuang Sun, Yuyan Guo, Yan Liu, Dayu Yang, Guoyu Li, Shaowa Lü
ETHNOPHARMACOLOGICAL RELEVANCE: Citri Reticulatae Pericarpium (Rutaceae, CRP), commonly called as Chenpi () in Chinese, is most frequently used as a qi-regulating drug in thousands of Chinese medicine prescriptions. CRP is found mainly in major citrus-producing areas such as the Guangdong, Guangxi, Sichuan, Fujian, and Zhejiang Provinces of China. Since thousands of years in China, CRP has been used widely in clinical practice to treat nausea, vomiting, indigestion, anepithymia, diarrhea, cough, expectoration, and so on...
April 5, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29615394/nephrotoxicity-and-chinese-herbal-medicine
#6
Bo Yang, Yun Xie, Maojuan Guo, Mitchell H Rosner, Hongtao Yang, Claudio Ronco
Chinese herbal medicine has been practiced for the prevention, treatment, and cure of diseases for thousands of years. Herbal medicine involves the use of natural compounds, which have relatively complex active ingredients with varying degrees of side effects. Some of these herbal medicines are known to cause nephrotoxicity, which can be overlooked by physicians and patients due to the belief that herbal medications are innocuous. Some of the nephrotoxic components from herbs are aristolochic acids and other plant alkaloids...
April 3, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29600756/potential-pharmacokinetic-herb-drug-interactions-have-we-overlooked-the-importance-of-human-carboxylesterases-1-and-2
#7
Jing Xu, Jin-Chun Qiu, Xing Ji, Hong-Li Guo, Xuan Wang, Bo Zhang, Tengfei Wang, Feng Chen
Herbal products have grown steadily across the globe over the past 10 years and have increasingly been incorporated into western medicine for healthcare aims, thereby causing potential pharmacokinetic herb-drug interactions (HDI) through the inhibition or induction of drug-metabolizing enzymes and transporters. Human carboxylesterases 1 (CES1) and 2 (CES2) are versatile enzymes involvement in the metabolism of endogenous and exogenous compounds including many important therapeutic medications. Moreover, the growing number of CES substrate drugs also underscores the importance of CES1 and CES2...
March 30, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29599697/links-between-the-prophet-muhammad-pbuh-recommended-foods-and-disease-management-a-review-in-the-light-of-modern-superfoods
#8
REVIEW
Sharique A Ali, Naima Parveen, Ayesha S Ali
Nutrition and other bioactive natural products present in specific foods within a balanced diet play an indispensable role in maintaining and promoting human health. Plants are rich sources of a balanced nutrition because of high content of bioactive products; hence, most of them recently have acquired the status of superfoods. It has been used since ancient times for the treatment of various ailments, and these traditional medicines still remain as one of the most affordable and easily accessible sources of treatment in the primary health-care system...
March 2018: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29558289/therapeutic-potential-of-glycyrrhetinic-acids-a-patent-review-2010-2017
#9
Hidayat Hussain, Ivan R Green, Umair Shamraiz, Muhammad Saleem, Amin Badshah, Ghulam Abbas, Najeeb Ur Rehman, Muhammad Irshad
Glycyrrhetinic acids (GAs) viz., 18β-glycyrrhetinic acid and 18α-glycyrrhetinic acid, are oleanane-type triterpenes having a carboxylic acid group at C-30, and are extracted from the Chines herbal medicine licorice (Glycyrrhiza uralensis). Although the pharmacological properties of GAs have long been known, attention to them has greatly increased in recent times due to their cytotoxic activity. Areas Covered: This review represents the patents granted about natural and synthetic glycyrrhetinic acid analogs from January 2010 to December 2017, the advances made by research groups in conjunction with pharmaceutical companies in the discovery of new natural or synthetic glycyrrhetinic acid analogs...
March 20, 2018: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/29526703/the-chemistry-and-pharmacology-of-ligularia-przewalskii-a-review
#10
REVIEW
Shi-Jun Liu, Zhi-Shu Tang, Zhi-Xin Liao, Chun-Li Cui, Hong-Bo Liu, Yan-Ni Liang, Yu Zhang, Hong-Bo Xu, Dong-Bo Zhang, Ya-Ting Zheng, Huan-Xian Shi, Shi-Ying Li
ETHNOPHARMACOLOGICAL RELEVANCE: Ligularia przewalskii (Maxim.) Diels (LP) (called zhangyetuowu in Chinese), is generally found in moist forest areas in the western regions of China. The root, leaves and flower of LP are utilized as a common traditional medicine in China. It has been utilized conventionally in herbal remedies for the remedy of haemoptysis, asthma, pulmonary phthisis, jaundice hepatitis, food poisoning, bronchitis, cough, fever, wound healing, measles, carbuncle, swelling and phlegm diseases...
March 8, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29512456/a-review-of-herbal-remedies-for-multiple-sclerosis-like-disorders-in-traditional-persian-medicine-tpm
#11
Mohammad M Zarshenas, Ramin Ansari, Amirhossein Dadbakhsh, Maryam Mohammadi
Among various neurological disorders, multiple sclerosis (MS) is an expanding global immune-related inflammatory disease with complex etiologies. There is increasing demand for the use and administration of natural medicaments for this disorder. Traditional Persian medicine (TPM) is a school of medicine and a medicinal plants-based resource for clinical studies put forward by Persian scholars. This paper aims to gather and study the effectiveness of all medicinal plants from the most popular Persian pharmacopeias...
March 5, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29512454/a-systems-pharmacology-study-for-deciphering-anti-depression-activity-of-nardostachys-jatamansi
#12
Saeideh Jalali, Amir Zarrinhaghighi, Saman Sadraei, Younes Ghasemi, Amirhossein Sakhteman, Pouya Faridi
Background The plant Nardostachys jatamansi from Valerianaceae family is a well known antidepressant plant and has historically been used in traditional medicine. As N. jatamansi contains many different compounds, to identify its mechanisms of action, we need a network-based study. Network-based studies are becoming an increasingly important tool in understanding the mechanisms of actions of drugs. Systems pharmacology (SP) and bioinformatics are two emerging tools that use computation to develop an understanding of drug actions in molecular and cellular levels...
March 5, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29506773/quality-markers-based-on-biological-activity-a-new-strategy-for-the-quality-control-of-traditional-chinese-medicine
#13
Xin Wu, Hongbing Zhang, Shanshan Fan, Yidan Zhang, Zhen Yang, Simiao Fan, Pengwei Zhuang, Yanjun Zhang
BACKGROUND: The quality and quality evaluation system of traditional Chinese medicine (TCM) are crucial in the safety and effectiveness assessment of TCM. However, they are also the major bottlenecks that restrict the quality control of TCM. Given the nature of Chinese medicine and the limitations of science and technology, the quality evaluation of TCM involves a few difficulties. Therefore, scholars have conducted considerable amount of research on this topic and obtained promising results...
February 7, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29499462/identification-characterization-and-hplc-quantification-of-formulation-related-impurities-of-honokiol-an-antitumor-natural-drug-candidate-in-clinical-trials
#14
Wenshuang Wu, Ming-Hai Tang, Huan Tang, Kai Chen, Jie Fu, Lun Wang, Lin-Lin Xue, Aihua Peng, Haoyu Ye, Li-Juan Chen
Natural products and their derivatives have historically been invaluable as a source of therapeutic agents. Honokiol, as a well-known natural product in Chinese herbal medicine Houpu, is finally being studied in a Phase I clinical trial (CTR20170822) in patients with Advanced Non-Small Cell Lung Cancer (NSCLS) in China this year. During the honokiol liposome formulation process, five major impurities were present in the range of 0.05-0.1% based on the HPLC analysis. These five major impurities were obtained from the forced degradation product of honokiol through countercurrent chromatography and prep-HPLC...
February 21, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29484023/integrative-dermatology-the-use-of-herbals-and-nutritional-supplements-to-treat-dermatological-conditions
#15
REVIEW
Michael Tirant, Torello Lotti, Serena Gianfaldoni, Georgi Tchernev, Uwe Wollina, Philip Bayer
From humble beginnings at the dawn of time to it's advanced and successful status today, this essay traces the history of natural medicine and the development of integrated dermatology to what it is today. Some of the most well-known natural (international and Australian) products with an application in dermatology are discussed. The history and functions of the Psoriasis Eczema Clinic and the products developed by its founder, Prof. Michael Tirant, are explained.
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29483872/herbal-components-of-a-novel-formula-psori-cm02-interdependently-suppress-allograft-rejection-and-induce-cd8-cd122-pd-1-regulatory-t-cells
#16
Chuanjian Lu, Huazhen Liu, Xiaowei Jin, Yuchao Chen, Chun-Ling Liang, Feifei Qiu, Zhenhua Dai
A recipient usually rejects a transplanted organ and thus needs immunosuppressive treatments to prevent rejection. Achieving long-term allograft survival without continuous global immunosuppression is highly desirable in transplantation as long-term immunosuppression causes various side effects. Therefore, it is necessary to search for medicine with potentially less side effects. Traditional Chinese medicine PSORI-CM01 (Yin Xie Ling), a formula with seven natural herbs, has been used to treat patients with psoriasis...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29483867/ethnopharmacological-approaches-for-dementia-therapy-and-significance-of-natural-products-and-herbal-drugs
#17
REVIEW
Devesh Tewari, Adrian M Stankiewicz, Andrei Mocan, Archana N Sah, Nikolay T Tzvetkov, Lukasz Huminiecki, Jarosław O Horbańczuk, Atanas G Atanasov
Dementia is a clinical syndrome wherein gradual decline of mental and cognitive capabilities of an afflicted person takes place. Dementia is associated with various risk factors and conditions such as insufficient cerebral blood supply, toxin exposure, mitochondrial dysfunction, oxidative damage, and often coexisting with some neurodegenerative disorders such as Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease (PD). Although there are well-established (semi-)synthetic drugs currently used for the management of AD and AD-associated dementia, most of them have several adverse effects...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29482046/pharmacological-values-and-therapeutic-properties-of-black-tea-camellia-sinensis-a-comprehensive-overview
#18
REVIEW
Muhammad Naveed, Jannat BiBi, Asghar Ali Kamboh, Imran Suheryani, Ihsanullah Kakar, Sarfaraz Ali Fazlani, Xia FangFang, Shahmir Ali Kalhoro, Liang Yunjuan, Mohib Ullah Kakar, Mohamed E Abd El-Hack, Ahmed E Noreldin, Shi Zhixiang, Chen LiXia, Zhou XiaoHui
Medicinal plants are essential parts of traditional medicine due to their phytochemical constituents having pharmacological values and therapeutic applications. Black tea have thousands of various biological compounds such as flavonoids (Thearubigins (TRs) and theaflavins (TFs) and catechins), amino acids (L.theanine), vitamins (A, C, K), phenolic acids (caffeic acid (CA), gallic acid (GA), chlorogenic acids (CGA) and cauramic acid), lipids, proteins, volatile compounds carbohydrates, β-carotene and fluoride that illustrated many promising pharmacological effects regarded as growth promoter, cardioprotector, potent cholesterol-lowering effect, antioxidant and antimicrobial, etc inhuman...
February 23, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29476434/complementary-medicines-in-pregnancy-recommendations-and-information-sources-of-healthcare-professionals-in-australia
#19
Christine E Gilmartin, To-Hao Vo-Tran, Laura Leung
Background The use of oral complementary and alternative medicines, including herbal supplements, has been increasing in pregnant women worldwide despite limited safety data. The decision of healthcare professionals to recommend these products to pregnant patients is controversial and not well documented. Objective To explore the recommendations and information sources that healthcare professionals use to determine the safety of oral non-prescribed supplements during pregnancy. Setting An Australian metropolitan maternity hospital...
February 23, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29476319/hypericum-japonicum-a-double-headed-sword-to-combat-vector-control-and-cancer
#20
Sreedev Puthur, A N Anoopkumar, Sharrel Rebello, Embalil Mathachan Aneesh
Mosquito control with naturally derived herbal insecticides has gained much momentum, with the increased insecticide resistance of vectors and the multiple infectious diseases spread by them. Yet, recent studies also suggest that mosquitoes could probably transmit some cancerous cells or cancer-causing viruses from one individual to another between their blood meals. The current research thus focused on the screening and characterization of novel plants with both mosquitocidal and anticancerous properties. Accordingly, different solvent extracts of Hypericum japonicum, a key plant in Chinese medicine, were screened for its larvicidal efficacy using the fourth instar larvae of Aedes aegypti (major vector of Dengue and chikungunya)...
February 24, 2018: Applied Biochemistry and Biotechnology
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