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https://www.readbyqxmd.com/read/28325144/therapeutic-potential-and-outlook-of-alternative-medicine-for-osteoporosis
#1
Tao Wang, Qian Liu, William Tjhioe, Jinmin Zhao, Aiping Lu, Ge Zhang, Renxiang Tan, Mengyu Zhou, Jiake Xu, Haotian Feng
Osteoporosis, a bone disease resulting in loss of bone density and microstructure quality, is often associated with fragility fractures, and the latter imposes a great burden on the patient and society. Although there are several different treatments available for osteoporosis such as hormone replacement therapy, bisphosphonates, Denosumab, and parathyroid hormone some concern has been raised regarding the inherent side effects of their long term use. It would be of great relevance to search for alternative natural compounds, which could complementarily overcome the limitations of the currently available therapy...
March 21, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28318753/-information-quality-and-health-risks-in-spanish-language-retail-websites-for-chinese-herbal-medicine
#2
Noelia Tejedor-García, Coral García-Pastor, Selma Benito-Martínez, Francisco Javier de Lucio-Cazaña
OBJECTIVE: The growing use of purchase online via Internet retailers favours the access to potentially toxic natural products. It also contributes to the quick dissemination of the claims made by the retailers on efficacy and safety, these claims being not always based upon reliable information. Here, we have conducted an online search to find Spanish-language retail websites for Chinese herbal medicine and we have analysed them for the quality of product information and the potential health risks...
March 16, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28289385/plant-derived-phytocompound-embelin-in-cns-disorders-a-systematic-review
#3
REVIEW
Uday P Kundap, Saatheeyavaane Bhuvanendran, Yatinesh Kumari, Iekhsan Othman, Mohd Farooq Shaikh
A Central nervous system (CNS) disease is the one which affects either the spinal cord or brain and causing neurological or psychiatric complications. During the nineteenth century, modern medicines have occupied the therapy for many ailments and are widely used these days. Herbal medicines have often maintained popularity for historical and cultural reasons and also considered safer as they originate from natural sources. Embelin is a plant-based benzoquinone which is the major active constituent of the fruits of Embelia ribes Burm...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28272545/glycyrrhiza-uralensis-water-extract-enhances-dendritic-cell-maturation-and-antitumor-efficacy-of-hpv-dendritic-cell-based-vaccine
#4
Adila Aipire, Jinyu Li, Pengfei Yuan, Jiang He, Yelang Hu, Lu Liu, Xiaoli Feng, Yijie Li, Fuchun Zhang, Jianhua Yang, Jinyao Li
Licorice has been used as herbal medicine and natural sweetener. Here, we prepared Glycyrrhiza uralensis water extract (GUWE) and investigated the effect of GUWE on the maturation and function of dendritic cells (DCs) and its adjuvant effect on DC-based vaccine. We observed that GUWE dose-dependently promoted DC maturation and cytokine secretion through TLR4 signaling pathway. The capacity of DC to stimulate allogenic splenocyte proliferation was also enhanced by GUWE treatment. Compared with control group, GUWE treated DCs pulsed with human papillomavirus (HPV)-16 E6/E7 peptides significantly inhibited the tumor growth in both early and late therapeutic groups...
March 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28265543/herbs-and-natural-supplements-in-the-prevention-and-treatment-of-delayed-onset-muscle-soreness
#5
REVIEW
Abbas Meamarbashi
OBJECTIVE: Unaccustomed and intense eccentric exercise is a common cause of delayed-onset muscle soreness (DOMS). There are multiple remedies for the treatment of DOMS, but its clinical and laboratory pieces of evidence are scarce. Currently, the treatments proposed for DOMS are numerous and include pharmaceuticals, herbal remedies, stretching, massage, nutritional supplements, and other alternatives. To find a holistic treatment with effective pain relief and minimum side effects, complementary and alternative medicine, including herbal therapies, plays a main role...
January 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28260045/a-herbal-formula-sykt-reverses-doxorubicin%C3%A2-induced-myelosuppression-and-cardiotoxicity-by-inhibiting-ros%C3%A2-mediated-apoptosis
#6
Ting Chen, Hong-Mei Shen, Zhi-Yong Deng, Zuo-Zhang Yang, Rui-Lian Zhao, Li Wang, Zhi-Ping Feng, Chao Liu, Wen-Hui Li, Zhi-Jie Liu
Doxorubicin (DOX) is an antineoplastic drug widely used for the treatment of various types of cancer; however, it can induce severe side effects, such as myelosuppression and cardiotoxicity. Sanyang Xuedai (SYKT) is a natural medicine originating from an ancient prescription of the Dai nationality in Southwest China. With eight Chinese herbal medicines, including sanguis draconis, radix et rhizoma notoginseng, radix et rhizoma glycyrrhizae and radix angelicae sinensis as the primary ingredients, SYKT has been reported to possess numerous biological functions...
March 1, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28259255/eurycoma-longifolia-as-a-potential-adoptogen-of-male-sexual-health-a-systematic-review-on-clinical-studies
#7
REVIEW
Hnin Ei Thu, Isa Naina Mohamed, Zahid Hussain, Putri Ayu Jayusman, Ahmad Nazrun Shuid
Eurycoma longifolia (EL) has been well recognized as a booster of male sexual health. Over the past few decades, numerous in vivo animal studies and human clinical trials have been conducted across the globe to explore the promising role of EL in managing various male sexual disorders, which include erectile dysfunction, male infertility, low libido, and downregulated testosterone levels. The aim of the present review is to analyze and summarize the literature on human clinical trials which revealed the clinical significance and therapeutic feasibility of EL in improving male sexual health...
January 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28257977/review-of-antidiabetic-fruits-vegetables-beverages-oils-and-spices-commonly-consumed-in-the-diet
#8
REVIEW
Maliheh Najari Beidokhti, Anna K Jäger
ETHNOPHARMACOLOGICAL RELEVANCE: Type 2 diabetes is the most common type of diabetes and its prevalence is rapidly increasing throughout the world. Modifications of lifestyle such as suitable diet and exercise programs along with pharmacotherapy and education of patients are beneficial therapies for patients with type 2 diabetes. The ethnopharmacological use of herbal medicines, many of them part of our diet as spices, vegetables and fruits, has been developed for the treatment of diabetes due to inexpensiveness, easy availability and few side effects...
February 28, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28256254/an-enhanced-targeted-identification-strategy-for-the-selective-identification-of-flavonoid-o-glycosides-from-carthamus-tinctorius-by-integrating-offline-two-dimensional-liquid-chromatography-linear-ion-trap-orbitrap-mass-spectrometry-high-resolution-diagnostic
#9
Chang-Liang Yao, Wen-Zhi Yang, Wei Si, Yao Shen, Nai-Xia Zhang, Hua-Li Chen, Hui-Qin Pan, Min Yang, Wan-Ying Wu, De-An Guo
Targeted identification of potentially bioactive molecules from herbal medicines is often stymied by the insufficient chromatographic separation, ubiquitous matrix interference, and pervasive isomerism. An enhanced targeted identification strategy is presented and validated by the selective identification of flavonoid O-glycosides (FOGs) from Carthamus tinctorius. It consists of four steps: (i) enhanced separation and detection by offline two-dimensional liquid chromatography/LTQ-Orbitrap MS (offline 2D-LC/LTQ-Orbitrap MS) using collision-induced dissociation (CID) and high-energy C-trap dissociation (HCD); (ii) improved identification of the major aglycones by acid hydrolysis and LC-SPE-NMR; (iii) simplified spectral elucidation by high-resolution diagnostic product ions/neutral loss filtering; and (iv) more convincing structural identification by matching an in-house library...
March 31, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28250790/application-of-spontaneous-photon-emission-in-the-growth-ages-and-varieties-screening-of-fresh-chinese-herbal-medicines
#10
Xiaolei Zhao, Jingxiang Pang, Jialei Fu, Meina Yang, Eduard Van Wijk, Yanli Liu, Hua Fan, Yufeng Zhang, Jinxiang Han
Ultraweak photon emission emitted by all living organisms has been confirmed to be a noninvasive indicator for their physiological and pathological characteristics. In this study, we investigated the characteristics of spontaneous photon emission (SPE) and the contents of specific active compounds of roots and flowers buds of several fresh Chinese herbal medicines (natural medicines) with different growth ages and varieties. The results revealed that the contents of specific active compounds from same species herbs with different growth ages and varieties were significantly different, and this difference could be reflected by their SPE...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28244788/carpoglyphus-lactis-carpoglyphidae-infestation-in-the-stored-medicinal-fructus-jujubae
#11
Xiao-Dong Zhan, Chao-Pin Li, Qi Chen
OBJECTIVE: To investigate the breeding rate and breeding density of Carpoglyphus lactisin stored Fructus Jujubaein Anhui, China in order to provide a scientific basis for prevention of Carpoglyphus lactis (C. lactis)from spoiling the dried fruit of such category. METHODS: By the breeding nature of C. lactis,we collected samples of Fructus Jujubae, which were kept over 6 months in general, from the dried fruit shop and (or) Chinese herbal medicine warehouse, and isolated C...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28239782/inhibition-of-klebsiella-pneumoniae-growth-by-selected-australian-plants-natural-approaches-for-the-prevention-and-management-of-ankylosing-spondylitis
#12
V Winnett, J Sirdaarta, A White, F M Clarke, I E Cock
A wide variety of herbal remedies are used in traditional Australian medicine to treat inflammatory disorders, including autoimmune inflammatory diseases. One hundred and six extracts from 40 native Australian plant species traditionally used for the treatment of inflammation and/or to inhibit bacterial growth were investigated for their ability to inhibit the growth of a microbial trigger for ankylosing spondylitis (K. pneumoniae). Eighty-six of the extracts (81.1%) inhibited the growth of K. pneumoniae. The D...
February 27, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28228098/anti-obesity-effect-of-ethanolic-extract-from-cosmos-caudatus-kunth-leaf-in-lean-rats-fed-a-high-fat-diet
#13
Hafeedza Abdul Rahman, Najla Gooda Sahib, Nazamid Saari, Faridah Abas, Amin Ismail, Muhammad Waseem Mumtaz, Azizah Abdul Hamid
BACKGROUND: Obesity is a major health concern both in developed and developing countries. The use of herbal medicines became the subject of interest for the management of obesity due to its natural origin, cost effectiveness and minimal side effects. The present study aimed at investigating anti-obesity potential of ethanolic extract from Cosmos caudatus Kunth leaf (EECCL). METHODS: In this study, the rats were randomly divided into six groups i.e., (1) Normal Diet (ND); (2) Normal Diet and 175 mg/kgBW of EECCL (ND + 175 mg/kgBW); (3) Normal Diet and 350 mg/kgBW of EECCL (ND + 350 mg/kgBW); (4) High Fat Diet (HFD); (5) High Fat Diet and 175 mg/kgBW of EECCL (HFD + 175 mg/kgBW); (6) High Fat Diet and 350 mg/kgBW of EECCL (HFD + 350 mg/kgBW)...
February 22, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28217454/erectile-dysfunction-treatment-and-traditional-medicine-can-east-and-west-medicine-coexist
#14
REVIEW
Joe K C Lee, Ronny B W Tan, Eric Chung
Erectile dysfunction (ED) is a common sexual problem affecting many men irrespective of cultures, beliefs and nationalities. While medical therapy for ED has been revolutionized by the advent of oral phosphodiesterase type 5 inhibitors and intracavernosal injection of vasoactive agents, recent technological advances such stem cell therapy, low intensity shock wave and newer generation of penile prosthesis implant offer hope to men who do not respond to conventional medical therapy. In contrast, traditional and complementary medicine (TCM) focuses on the restoration and better overall bodily regulation with the use of various herbal and animal products as well as exercises to invigorate qi (energy) in vital organs...
February 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28216951/a-qualitative-insight-on-complementary-and-alternative-medicines-used-by-hypertensive-patients
#15
Inas Rifaat Ibrahim, Mohamed Azmi Hassali, Fahad Saleem, Haydar F Al Tukmagi
BACKGROUND: The self-treatment with complementary and alternative medicines (CAMs) in chronic diseases is portraying an expanding trend worldwide. Yet, little is known concerning patients' motives to use CAM in the control of blood pressure. OBJECTIVE: This study aims to explore the self-use of CAM in the management of hypertension and explore patients' attitudes, perceived benefits, and disclosure to the physician. MATERIALS AND METHODS: A qualitative technique was adopted and face-to-face interviews, using a validated interview guide, were carried out among twenty hypertensive patients...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28212843/natural-extranuclear-androgen-receptor-ligands-as-endocrine-disruptors-of-cancer-cell-growth
#16
Marilena Kampa, George Notas, Elias Castanas
Even though the term endocrine disruption primarily designates environmental chemicals that can interfere with the action of hormones, in recent years it has been extended to include also plant derived compounds that can reach the human body, naturally, or have been identified and studied as alternative pharmaceutical agents. In fact, for a large number of them, their antihormonal action was appreciated by different traditional herbal medicines. In the present review we report the majority of the plant derived compounds that exhibit an antiandrogenic effect and the known mechanisms of action...
February 14, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28198055/traditional-oriental-herbal-medicine-and-natural-killer-cells-for-cancer-patients-a-systematic-review-and-meta-analysis
#17
REVIEW
Kyeore Bae, Ji-Hye Park, Jeehye Kim, Chong-Kwan Cho, Byeongsang Oh, Daniel Costa, Stephanie Lim, Gary Deng, Hwa-Seung Yoo
Traditional oriental herbal medicine (HM) is used by cancer patients to improve immunity. Natural killer (NK) cells are associated with development and progression of tumor and survival of cancer patients. This literature review examined randomized controlled trials (RCTs) in four electronic databases until October 2015 to evaluate the effects of oral HM on NK cells in cancer patients. Data were pooled and computed in a meta-analysis. The methodological quality was assessed according to the Cochrane risk of bias tool...
February 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28194217/schisandra-chinensis-and-morus-alba-synergistically-inhibit-in-vivo-thrombus-formation-and-platelet-aggregation-by-impairing-the-glycoprotein-vi-pathway
#18
Dong-Seon Kim, Muhammad Irfan, Yoon-Young Sung, Seung Hyung Kim, Sun Haeng Park, Young Hyun Choi, Man Hee Rhee, Ho Kyoung Kim
Morus alba L. (MAL) extract has been used in traditional medicine for its cardioprotective and antiplatelet effects, while another herbal remedy, Schisandra chinensis (SCC), has been reported to have anti-inflammatory and antioxidant properties. We evaluated underlying cellular changes exerted by extracts of these plants on platelet function and effects of SCC + MAL on in vivo thrombus formation using AV shunt and tail thrombosis-length models in rats. In vitro platelet aggregation, granule secretion, and [Ca(2+)] i release assays were carried out...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28182702/natural-formulas-and-the-nature-of-formulas-exploring-potential-therapeutic-targets-based-on-traditional-chinese-herbal-formulas
#19
Qianru Zhang, Hua Yu, Jin Qi, Daisheng Tang, Xiaojia Chen, Jian-Bo Wan, Peng Li, Hao Hu, Yi-Tao Wang, Yuanjia Hu
By comparing the target proteins (TPs) of classic traditional Chinese medicine (TCM) herbal formulas and modern drugs used for treating coronary artery disease (CAD), this study aimed to identify potential therapeutic TPs for treating CAD. Based on the theory of TCM, the Xuefu-Zhuyu decoction (XZD) and Gualou-Xiebai-Banxia decoction (GXBD), both of which are classic herbal formulas, were selected for treating CAD. Data on the chemical ingredients and corresponding TPs of the herbs in these two formulas and data on modern drugs approved for treating CAD and related TPs were retrieved from professional TCM and bioinformatics databases...
2017: PloS One
https://www.readbyqxmd.com/read/28133516/evaluation-of-estrogenic-activity-of-extract-from-the-herbal-mixture-cynanchum-wilfordii-hemsley-phlomis-umbrosa-turczaninow-and-angelica-gigas-nakai
#20
Se Jong Kim, Sun Woo Jin, Gi-Ho Lee, Yong An Kim, Hye Gwang Jeong
Hormone replacement therapy (HRT) consists of highly effective prescription medications for treating menopausal symptoms; however, these agents have exhibited side effects including the risk of estrogen-induced carcinogenesis. Therefore, interest in phytotherapy-based materials as a natural source of alternatives to estrogen therapy has increased. However, some of these herbal medicines have been reported to increase the risk of estrogen-induced cancer. Herbal formulations composed of a combination of Cynanchum wilfordii Hemsley (CW), Phlomis umbrosa Turczaninow (PU), and Angelica gigas Nakai (AG) extracts (CPAE) have been used for treating menopausal symptoms...
January 2017: Toxicological Research
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