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https://www.readbyqxmd.com/read/28635494/urea-cycle-disorder-misdiagnosed-as-multiple-sclerosis-a-case-report-and-review-of-the-literature
#1
Hussein Algahtani, Seham Alameer, Yousef Marzouk, Bader Shirah
Urea cycle disorders are a group of inborn errors of metabolism caused by dysfunction of any of the six enzymes or two transport proteins involved in urea biosynthesis. In this paper, we report a patient who presented with neurological dysfunction and coma in the immediate postpartum period. She was misdiagnosed for many years as a case of multiple sclerosis. The importance of reporting this case is to illustrate that the wrong diagnosis of patients as being affected with multiple sclerosis for many years due to magnetic resonance imaging abnormalities rather than the classic relapsing-remitting nature of the disease may lead to catastrophic consequences...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28634379/the-effect-of-weak-acid-anions-on-the-selective-catalytic-wet-air-oxidation-of-aqueous-ammonia-to-nitrogen
#2
Zidan Wang, Sohaib Hameed, Yaoyao Wen, Nuowei Zhang, Hengjun Gai, Jinbao Zheng, Bing H Chen
In this work, the effect of weak acid anions on the ammonia removal has been extensively studied for the process of selective catalytic wet air oxidation (CWAO) of ammonia to nitrogen. It is found that the presence of weak acid anions can effectively enhance the ammonia conversion and selectivity towards nitrogen. The combination between the weak acid anions and H(+) to produce weak acid molecules is responsible for such enhancement. Firstly, the H(+) consumption of weak acid anions can increase the NH3 concentration and thus the reactivity of ammonia oxidation, due to the shift to NH3 on the equilibrium of NH4(+)/NH3...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28633353/modulating-role-of-ros-in-re-establishing-desiccation-tolerance-in-germinating-seeds-of-caragana-korshinskii-kom
#3
Long Peng, Sirui Lang, Yu Wang, Hugh W Pritchard, Xiaofeng Wang
In close agreement with visible germination, orthodox seeds lose desiccation tolerance (DT). This trait can be regained under osmotic stress, but the mechanisms are poorly understood. In this study, germinating seeds of Caragana korshinskii Kom. were investigated, focusing on the potential modulating roles of reactive oxygen species (ROS) in the re-establishment of DT. Germinating seeds with 2 mm long radicles can be rendered tolerant to desiccation by incubation in a polyethylene glycol (PEG) solution (-1...
June 15, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28632388/accelerating-dynamics-of-h-on-graphene-by-coadsorbates
#4
Manh-Thuong Nguyen, Phong Nam Pham
There are several factors that affect the dynamics of adsorbed hydrogen atoms on a carbon surface, here, using density-functional calculations we show that coadsorption can be a highly influential factor. The diffusion of hydrogen adsorbed on graphene is explored in the presence of H-containing molecules. Without coadsorbates the diffusion barrier of H on graphene is 0.94 eV while with water/ammonia it is 0.85/0.12 eV. The low barrier in the case of ammonia is attributed to the formation of a stable intermediate state NH$_4$ while such a stable state is not found in the case of water...
June 20, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28630420/functional-evaluation-of-a-bioartificial-liver-support-system-using-immobilized-hepatocyte-spheroids-in-a-porcine-model-of-acute-liver-failure
#5
Ji-Hyun Lee, Doo-Hoon Lee, Sanghoon Lee, Choon Hyuck David Kwon, Jae-Nam Ryu, Jeong-Kwon Noh, In Keun Jang, Hey-Jung Park, Hee-Hoon Yoon, Jung-Keug Park, Young-Jin Kim, Sung-Koo Kim, Suk-Koo Lee
Bioartificial livers (BAL) may offer acute liver failure (ALF) patients an opportunity for cure without liver transplantation. We evaluated the efficacy of a spheroid-based BAL system, containing aggregates of porcine hepatocytes, in a porcine model of ALF. ALF pigs were divided into three groups. The control group consisted of treatment naïve pigs (n = 5), blank group consisted of pigs that were attached to the BAL system not containing hepatocytes for 12 hours (n = 5) and BAL group consisted of pigs that were attached to the BAL containing hepatocytes for 12 hours (n = 5)...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28629812/benthic-foraminifera-for-heavy-metal-pollution-monitoring-a-case-study-from-burullus-lagoon-of-egypt
#6
O H Orabi, A A El-Badry, A M Badr-ElDin
Sources of heavy metals pollution in the Burullus Lagoon include phosphate fertilizers, sewage and oil spills from fishing boats. The benthic species identified in this lagoon are Adelosina carinata striata (Wiesner), Quinqueloculina bosciana (d'Orbigny), Quinqueloculina seminulum (Linnaeus), Ammonia tepida (Cushman), Elphidium excavatum (Terquem). A. tepida is the most dominant species in the lagoon. It constitutes more than 97% of the total benthic foraminiferal assemblages reflecting tolerance to the very low salinity in the Burullus Lagoon...
June 16, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28629707/theoretical-investigation-of-the-selective-dehydration-and-dehydrogenation-of-ethanol-catalyzed-by-small-molecules
#7
Yanqun Wang, Yizhen Tang, Youxiang Shao
Catalytic dehydration and dehydrogenation reactions of ethanol have been investigated systematically using the ab initio quantum chemistry methods The catalysts include water, hydrogen peroxide, formic acid, phosphoric acid, hydrogen fluoride, ammonia, and ethanol itself. Moreover, a few clusters of water and ethanol were considered to simulate the catalytic mechanisms in supercritical water and supercritical ethanol. The barriers for both dehydration and dehydrogenation can be reduced significantly in the presence of the catalysts...
May 17, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28628989/pollutant-removal-and-microorganism-evolution-of-activated-sludge-under-ofloxacin-selection-pressure
#8
Qiang Kong, Xiao He, Yu Feng, Ming-Sheng Miao, Qian Wang, Yuan-da Du, Fei Xu
An activated sludge sequencing batch reactor (SBR) was fed with synthetic wastewater containing ofloxacin (OFL) for 52days to study the overall performance of the SBR, the characteristics of extracellular polymeric substances (EPS) and the bacterial community shift. Removal efficiencies of chemical oxygen demand, ammonia nitrogen, phosphorus and OFL were maintained at 90%, 96%, 80% and 65%, respectively. The EPS contents increased with increasing OFL concentration because more EPS was secreted to protect cells from OFL damage...
June 14, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28627715/transition-and-alkali-metal-complex-ternary-amides-for-ammonia-synthesis-and-decomposition
#9
Hujun Cao, Jianping Guo, Fei Chang, Claudio Pistidda, Wei Zhou, Xilun Zhang, Antonio Santoru, Hui Wu, Norbert Schnell, Rainer Niewa, Ping Chen, Thomas Klassen, Martin Dornheim
A new complex ternary amide Rb2[Mn(NH2)4], which contains both transition and alkali metal catalytic sites, is synthesized by mechanochemical reaction. It exhibits two temperature-dependent polymorphs i.e. low-temperature orthorhombic and high-temperature monoclinic structures. Rb2[Mn(NH2)4] decomposes to N2, H2, NH3, Mn3N2, and RbNH2 under inert atmosphere; whereas releases NH3 at 80 °C under H2 atmosphere. Those unique behaviors enable Rb2[Mn(NH2)4] and K2[Mn(NH2)4] as excellent materials for NH3 decomposition and synthesis...
June 19, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28627027/elevated-serum-myostatin-level-is-associated-with-worse-survival-in-patients-with-liver-cirrhosis
#10
Hiroki Nishikawa, Hirayuki Enomoto, Akio Ishii, Yoshinori Iwata, Yuho Miyamoto, Noriko Ishii, Yukihisa Yuri, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Ryo Takata, Hiroko Iijima, Shuhei Nishiguchi
BACKGROUND: We aimed to elucidate the relationship between serum myostatin levels and other markers including skeletal muscle mass and to investigate the influence of serum myostatin levels on survival for patients with liver cirrhosis (LC). METHODS: A total of 198 LC subjects were analysed in this study. Myostatin levels were measured using stored sera. We retrospectively investigated the relationship between myostatin level and other markers, and the influence of myostatin level on overall survival (OS)...
June 18, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28625109/the-study-of-a-pilot-scale-aerobic-fenton-anoxic-aerobic-process-system-for-the-treatment-of-landfill-leachate
#11
Wenyong Hu, Yu Zhou, Xiaobo Min, Jingyi Liu, Xinyu Li, Lin Luo, Jiachao Zhang, Qiming Mao, Liyuan Chai, YaoYu Zhou
In this study, a combined Aerobic-Fenton-Anoxic/Aerobic system was designed for the remediation of raw landfill leachate in a pilot-scale experiment. This system included: i) a granular sludge biological oxidation procedure that achieves the accumulation of nitrite nitrogen (NO2(-)-N) under aerobic conditions; ii) a Fenton process that improves the biodegradability of the bio-treated leachate; and iii) an activated sludge biological oxidation component under anoxic and aerobic conditions. Additionally, a shortcut nitrification and denitrification pathway was achieved...
June 19, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28624728/nitrite-production-from-urine-for-sulfide-control-in-sewers
#12
Min Zheng, Zhiqiang Zuo, Yizhen Zhang, Yujia Cui, Qian Dong, Yanchen Liu, Xia Huang, Zhiguo Yuan
Most commonly used methods for sewer sulfide control involves dosing chemical agents to wastewater, which incurs high operational costs. Here, we propose and demonstrate a cost-effective and environmentally attractive approach to sewer sulfide control through urine separation and its subsequent conversion to nitrite prior to intermittent dosage to sewers. Urine collected from a male toilet urinal was fed to laboratory-scale sequencing batch reactors. The reactors stably converted roughly 50% of the nitrogen in urine to nitrite, with high abundance (at 17...
May 23, 2017: Water Research
https://www.readbyqxmd.com/read/28622648/long-term-sustainability-of-microbial-induced-caco3-precipitation-in-aqueous-media
#13
Daniella Gat, Zeev Ronen, Michael Tsesarsky
Microbially induced CaCO3 precipitation (MICP) via urea hydrolysis is an emerging technique for soil amelioration, building materials rehabilitation and pollutants sequestration amongst other various environmental applications. The successful application of MICP requires the sustainability of the precipitated CaCO3; to which the fate of ammonia, the main by-product of ureolysis, is potentially significante. Ammonia volatilization and biological ammonia oxidation both induce a pH decrease, which, in turn, might cause CaCO3 dissolution...
June 7, 2017: Chemosphere
https://www.readbyqxmd.com/read/28621836/-dietary-advanced-glycation-end-products-modify-gut-microbial-composition-and-partially-increase-colon-permeability-in-rats
#14
Wanting Qu, Xiaojin Yuan, Jinsong Zhao, Yingxiao Zhang, Jing Hu, Jiawei Wang, Juxiu Li
SCOPE: The adverse impacts of dietary advanced glycation end products (AGEs) on health are currently of interest. These compounds are inevitably formed during thermal food processing and make foods less digestible because of protein cross-linking. This study examined not only whether dietary AGEs alter cecal microbiota and their metabolites but also their effects on colon permeability. METHODS AND RESULTS: Sprague-Dawley rats were exposed to a high-AGEs diet (AGEs content was increased by heating food at 125°C/3 h) for 6, 12, or 18 weeks...
June 16, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28621738/integration-of-p-cuo-thin-sputtered-layers-onto-microsensor-platforms-for-gas-sensing
#15
Lionel Presmanes, Yohann Thimont, Imane El Younsi, Audrey Chapelle, Frédéric Blanc, Chabane Talhi, Corine Bonningue, Antoine Barnabé, Philippe Menini, Philippe Tailhades
P-type semiconducting copper oxide (CuO) thin films deposited by radio-frequency (RF) sputtering were integrated onto microsensors using classical photolithography technologies. The integration of the 50-nm-thick layer could be successfully carried out using the lift-off process. The microsensors were tested with variable thermal sequences under carbon monoxide (CO), ammonia (NH₃), acetaldehyde (C₂H₄O), and nitrogen dioxide (NO₂) which are among the main pollutant gases measured by metal-oxide (MOS) gas sensors for air quality control systems in automotive cabins...
June 16, 2017: Sensors
https://www.readbyqxmd.com/read/28621016/acute-effects-of-phenylbutyrate-on-glutamine-branched-chain-amino-acid-and-protein-metabolism-in-skeletal-muscles-of-rats
#16
Milan Holecek, Melita Vodenicarovova, Pavel Siman
Phenylbutyrate (PB) acts as chemical chaperone and histone deacetylase inhibitor, which is used to decrease ammonia in urea cycle disorders and has been investigated for use in the treatment of a number of lethal illnesses. We performed in vivo and in vitro experiments to examine the effects of PB on glutamine (GLN), branched-chain amino acid (BCAA; valine, leucine and isoleucine) and protein metabolism in rats. In the first study, animals were sacrificed one hour after three injections of PB (300mg/kg b...
June 16, 2017: International Journal of Experimental Pathology
https://www.readbyqxmd.com/read/28620947/effect-of-applying-cinnamaldehyde-incorporated-in-wax-on-green-mold-decay-in-citrus-fruits
#17
Xiaofang Duan, Qiuli OuYang, Nengguo Tao
BACKGROUND: Green mold caused by Penicillium digitatum is the most damaging postharvest diseases of citrus fruit. Cinnamaldehyde (CA) is a food additive that has potential use in controlling postharvest disease of fruits and vegetables. In this study, the effectiveness of wax with CA (WCA) in controlling Ponkan (Citrus reticulata Blanco) green mold was investigated. RESULTS: The mycelial growth of P. digitatum was inhibited by CA in a dose-dependent manner. The minimum inhibitory concentration and minimum fungicidal concentration (MFC) were both 0...
June 16, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28620026/learning-to-read-and-write-in-evolution-from-static-pseudoenzymes-and-pseudosignalers-to-dynamic-gear-shifters
#18
REVIEW
Abulikemu Abudukelimu, Thierry D G A Mondeel, Matteo Barberis, Hans V Westerhoff
We present a systems biology view on pseudoenzymes that acknowledges that genes are not selfish: the genome is. With network function as the selectable unit, there has been an evolutionary bonus for recombination of functions of and within proteins. Many proteins house a functionality by which they 'read' the cell's state, and one by which they 'write' and thereby change that state. Should the writer domain lose its cognate function, a 'pseudoenzyme' or 'pseudosignaler' arises. GlnK involved in Escherichia coli ammonia assimilation may well be a pseudosignaler, associating 'reading' the nitrogen state of the cell to 'writing' the ammonium uptake activity...
June 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28619162/impact-of-treatments-for-recycled-broiler-litter-on-the-viability-and-infectivity-of-microorganisms
#19
Daiane Voss-Rech, Iara Maria Trevisol, Liana Brentano, Virgínia Santiago Silva, Raquel Rebelatto, Fátima Regina Ferreira Jaenisch, Cintia Hiromi Okino, Marcos Antonio Zanella Mores, Arlei Coldebella, Sônia de Avila Botton, Clarissa Silveira Luiz Vaz
The microbiological risk of recycled litter depends on the efficacy of the management system applied to inactivate residual microorganisms and preserve the health of the successive broiler flock. This study aimed to assess the viability and infectivity of the Newcastle Disease Virus (NDV), Infectious Bursal Disease Virus (IBDV) and Salmonella Heidelberg in recycled litter exposed to different treatments. The litter was contaminated with microorganisms and submitted to the treatments (T): T1: shallow fermentation; T2: quicklime (calcium oxide); T3: shallow fermentation followed by addition of quicklime; T4: no treatment...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28619110/effect-of-aspartic-acid-and-glutamate-on-metabolism-and-acid-stress-resistance-of-acetobacter-pasteurianus
#20
Haisong Yin, Renkuan Zhang, Menglei Xia, Xiaolei Bai, Jun Mou, Yu Zheng, Min Wang
BACKGROUND: Acetic acid bacteria (AAB) are widely applied in food, bioengineering and medicine fields. However, the acid stress at low pH conditions limits acetic acid fermentation efficiency and high concentration of vinegar production with AAB. Therefore, how to enhance resistance ability of the AAB remains as the major challenge. Amino acids play an important role in cell growth and cell survival under severe environment. However, until now the effects of amino acids on acetic fermentation and acid stress resistance of AAB have not been fully studied...
June 15, 2017: Microbial Cell Factories
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