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Platelet rich fibrine

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https://www.readbyqxmd.com/read/29921309/is-local-platelet-rich-plasma-injection-clinically-superior-to-hyaluronic-acid-for-treatment-of-knee-osteoarthritis-a-systematic-review-of-randomized-controlled-trials
#1
Yalong Di, Changxu Han, Liang Zhao, Yizhong Ren
BACKGROUND: In this study, we evaluated whether platelet-rich plasma (PRP) is superior to hyaluronic acid (HA) in the treatment of knee osteoarthritis. METHODS: The Cochrane Central Register of Controlled Trials, PubMed, and Embase databases were searched for English-language, human in vivo studies on the treatment of symptomatic knee osteoarthritis with intra-articular PRP compared with HA. The following keywords were used for the search: "platelet-rich plasma," "PRP," "platelet-rich fibrin," "PRF," "platelet," "plasma," "arthritis," "osteoarthritis," "gonarthrosis," and "degeneration...
June 19, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29894435/concentrated-growth-factor-enhanced-fat-graft-survival-a-comparative-study
#2
Yun Hu, Yichen Jiang, Muyao Wang, Weidong Tian, Hang Wang
BACKGROUND: Concentrated growth factors (CGFs) belong to a new generation biomaterials that concentrate large number of growth factors and CD34 stem cells in small volume of plasma. OBJECTIVE: The purpose of this study was to evaluate the impact of the new technique, CGF, on fat graft survival, which compared with platelet-rich plasma (PRP) and platelet-rich fibrin (PRF). MATERIALS AND METHODS: Nude mice received fat graft were divided into PRP group, PRF group, CGF group, and saline...
June 8, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29893477/comparison-of-the-clinical-radiographic-and-histological-effects-of-titanium-prepared-platelet-rich-fibrin-to-allograft-materials-in-sinus-lifting-procedures
#3
Ebru Olgun, Serdar Y Ozkan, Hasan T Atmaca, Mehmet Yalim, Meltem Karsiyaka Hendek
AIM: In the present study, we evaluated the clinical, radiographic, and histological comparisons of completely autologous titanium-prepared platelet rich fibrin (T-PRF) or allograft in sinus-lifting procedures. METHODS: Eighteen posterior maxilla requiring sinus-lifting procedures using the balloon-lifting technique for implant placement were selected. Ten sinuses were randomly assigned to T-PRF as the test group and eight to allografts as the control group. After 4 and 6 months in the test and control groups, respectively, computed tomography was done, and bone samples were received during implant surgery...
June 12, 2018: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/29890349/healing-after-resection-of-colonic-endometriosis-and-growth-factor-enriched-agents-an-experimental-rat-model
#4
Anastasia Prodromidou, Kitty Pavlakis, Vasileios Pergialiotis, Maximos Frountzas, Nikolaos Machairas, Ioannis D Kostakis, Laskarina M Korou, Konstantinos Stergios, Dimitrios Dimitroulis, George Vaos, Despoina N Perrea
STUDY OBJECTIVE: To examine the potential beneficial effect of platelet rich plasma (PRP) and fibrin sealant (TISSEEL; Baxter Healthcare Corporation, Deerfield, IL) on bowel wound healing after shaving of an experimentally induced endometriotic lesion. DESIGN: Single-blind, randomized study (Canadian Task Force classification I). SETTING: Certified animal research facility. ANIMALS: Thirty female Sprague-Dawley rats...
June 8, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29881226/the-use-of-platelet-rich-fibrin-with-platelet-rich-plasma-support-meniscal-repair-surgery
#5
Masahiko Kemmochi, Shigeru Sasaki, Masako Takahashi, Tomitaka Nishimura, Chisa Aizawa, Jun Kikuchi
Introduction: Platelet-rich fibrin (PRF) is the only autologous blood product that releases growth factors and has scaffolding properties. We hypothesized that the use of PRF and Platelet-rich plasma (PRP) would improve operative results, including the recovery of function and repaired meniscus. Materials and Methods: Seventeen patients underwent arthroscopic meniscus repair with PRF and PRP (PRF group) using our novel device for the injection of the PRF into the joint...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29875563/augmentation-of-interdental-papilla-with-platelet-rich-fibrin
#6
E Ahila, R Saravana Kumar, Vineela Katam Reddy, B Pratebha, M Jananni, V Priyadharshini
Background: Dental esthetics has become a great concern for both dental practitioners and patients in addition to maintaining oral health. The presence of interproximal papillae between the maxillary anterior teeth is a key esthetic component. Recession of interdental papilla leads to various functional problems such as food impaction, phonetics and esthetic problems such as the formation of black triangle which poses a great challenge. Aim: This study aims to evaluate the augmentation of interdental papilla with platelet-rich fibrin...
April 2018: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29875559/comparative-evaluation-of-coronally-advanced-flap-using-amniotic-membrane-and-platelet-rich-fibrin-membrane-in-gingival-recession-an-18-month-clinical-study
#7
Mohd Rehan, Manish Khatri, Mansi Bansal, Komal Puri, Ashish Kumar
Background: An amnion membrane is a placenta-derived tissue that consists of numerous growth factors, proteins, and stem cell reserves which help in accelerated wound healing and regeneration. Platelet-rich fibrin (PRF) also releases growth factors after activation from the platelets and gets trapped within fibrin matrix which has been shown to stimulate the mitogenic response in the periosteum for bone repair and regeneration during normal wound healing. This preliminary, controlled, randomized clinical trial with an 18-month follow-up was aimed to evaluate the effectiveness of coronally advanced flap (CAF) with either PRF membrane or bioresorbable amniotic membrane (AM) in treatment of localized gingival recession defects...
April 2018: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29872915/plasma-rich-fibrin-in-neurosurgery-a-feasibility-study
#8
Tom Theys, Anais Van Hoylandt, Charlotte-Elise Broeckx, Laura Van Gerven, Joyce Jonkergouw, Marc Quirynen, Johannes van Loon
BACKGROUND: Cerebrospinal fluid (CSF) leakage represents an important and sometimes challenging complication in both cranial and spinal surgery. Current available options for dural closure pose inherent problems regarding safety, efficacy, immunogenicity, cost, and invasiveness. In this article, the use of leukocyte- and platelet-rich fibrin (L-PRF) derived from the patient's own blood is proposed to facilitate dural closure. We aim to describe the safety, feasibility, and applicability of L-PRF membranes and plugs in cranial and spinal neurosurgery...
June 6, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29870308/fifteen-years-of-platelet-rich-fibrin-prf-in-dentistry-and-oromaxillofacial-surgery-how-high-is-the-level-of-scientific-evidence
#9
Shahram Ghanaati, Carlos Herrera-Vizcaino, Sarah Al-Maawi, Jonas Lorenz, Richard J Miron, Katja Nelson, Frank Schwarz, Joseph Choukroun, Robert Sader
Platelet-rich fibrin is a blood concentrate system used for soft tissue and bone tissue regeneration. In the last decade, platelet rich fibrin (PRF) has been widely used in different indication fields, particularly in oral and maxillofacial surgery. This review is aimed to investigate the level of scientific evidence of published articles related to the use of PRF for bone and soft tissue regeneration in dentistry and maxillofacial surgery. An electronic literature research using the biomedical search engine "National Library of Medicine" (PubMed-MEDLINE) was performed in May 2017...
June 5, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29861812/using-microfluidic-devices-to-study-thrombosis-in-pathological-blood-flows
#10
Bradley A Herbig, Xinren Yu, Scott L Diamond
Extreme flows can exist within pathological vessel geometries or mechanical assist devices which create complex forces and lead to thrombogenic problems associated with disease. Turbulence and boundary layer separation are difficult to obtain in microfluidics due to the low Reynolds number flow in small channels. However, elongational flows, extreme shear rates and stresses, and stagnation point flows are possible using microfluidics and small perfusion volumes. In this review, a series of microfluidic devices used to study pathological blood flows are described...
July 2018: Biomicrofluidics
https://www.readbyqxmd.com/read/29858875/l-prf-for-increasing-the-width-of-keratinized-mucosa-around-implants-a-split-mouth-randomized-controlled-pilot-clinical-trial
#11
A Temmerman, G J Cleeren, A B Castro, W Teughels, M Quirynen
BACKGROUND: This study aims to evaluate the use of the leukocyte- and platelet-rich fibrin (L-PRF) membranes in increasing the width of the keratinized mucosa (KM) around implants. MATERIAL AND METHODS: Eight patients in need for bilateral widening of the KM around implants in the lower jaw were recruited for a spit-mouth randomized controlled trial. At the control site, a free gingival graft (FGG) was used, whereas at the other side (test), L-PRF membranes were applied...
June 2, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29847961/sinus-augmentation-using-platelet-rich-fibrin-with-or-without-a-bone-graft-what-is-the-consensus
#12
Richard J Miron, Michael A Pikos
Regenerative therapies with platelets have been widely used in medicine over the past two decades as a means to speed revascularization to damaged/defective tissues. Within the oral cavity, the sinus is one of the least vascularized areas with healing times typically increased to augment lost or missing bone. As a result, attempts have been proposed to combine platelet concentrates with various biomaterials to accelerate new blood flow to these tissues and ultimately facilitate new bone regeneration. While platelet-rich plasma (PRP) was introduced as a first-generation platelet concentrate, more recently platelet-rich fibrin (PRF) has been developed with anticoagulant removal from centrifugation protocols...
June 2018: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29782513/high-red-blood-cell-composition-in-clots-is-associated-with-successful-recanalization-during-intra-arterial-thrombectomy
#13
Jong Wook Shin, Hye Seon Jeong, Hyon-Jo Kwon, Kyu Sang Song, Jei Kim
We evaluated the composition of individual clots retrieved during intra-arterial thrombectomy in relation to recanalization success, stroke subtype, and the presence of clot signs on initial brain images. We analyzed clot and interventional data from 145 retrieval trials performed for 37 patients (69.5±14.0 years, 20 men, large artery atherosclerosis, n = 7; cardioembolism, n = 22; undetermined etiology, n = 8) who had undergone intra-arterial thrombectomy. Rates of clot retrieval and successful recanalization (Arterial Occlusive Lesion score of 2-3) for separate retrieval trials were evaluated...
2018: PloS One
https://www.readbyqxmd.com/read/29781765/individualized-titanium-mesh-combined-with-platelet-rich-fibrin-and-deproteinized-bovine-bone-a-new-approach-for-challenging-augmentation
#14
Jonas Lorenz, Sarah Al-Maawi, Robert Sader, Shahram Ghanaati
Autologous bone transfer is regarded as the gold standard for ridge augmentation before dental implantation, especially in severe bony defects caused by tumor resection or atrophy. In addition to the advantages of autologous bone, transplantation has several disadvantages, such as secondary operation, increased morbidity and pain. The present study reports, for the first time, a combination of a xenogeneic bone substitute (BO) with platelet-rich fibrin (PRF), which is a fully autologous blood concentrate derived from the patient's own peripheral blood by centrifugation...
May 21, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29777616/regenerative-endodontics-a-review
#15
REVIEW
S G Kim, M Malek, A Sigurdsson, L M Lin, B Kahler
The European Society of Endodontology and the American Association for Endodontists have released position statements and clinical considerations for regenerative endodontics. There is increasing literature on this field since the initial reports of Iwaya et al. (2001) and Banchs & Trope (2004). Endogenous stem cells from an induced periapical bleeding and scaffolds using blood clot, platelet rich plasma or platelet rich fibrin have been utilized in regenerative endodontics. This approach has been described as a 'paradigm shift" and considered the first treatment option for immature teeth with pulp necrosis...
May 19, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29772345/autologous-liquid-platelet-rich-fibrin-a-novel-drug-delivery-system
#16
REVIEW
Richard J Miron, Yufeng Zhang
There is currently widespread interest within the biomaterial field to locally deliver biomolecules for bone and cartilage regeneration. Substantial work to date has focused on the potential role of these biomolecules during the healing process, and the carrier system utilized is a key factor in their effectiveness. Platelet rich fibrin (PRF) is a naturally derived fibrin scaffold that is easily obtained from peripheral blood following centrifugation. Slower centrifugation speeds have led to the commercialization of a liquid formulation (liquid-PRF) resulting in an upper plasma layer composed of liquid fibrinogen/thrombin prior to clot formation that remains in its liquid phase for approximately 15 minutes until injected into bodily tissues...
May 14, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29769770/clinical-and-histological-evaluation-on-application-of-platelet-concentrates-on-depigmented-gingival-epithelium
#17
Koel Debnath, Anirban Chatterjee
Background: The platelet concentrate is a windfall in the field of regenerative therapy in periodontology. It accelerates wound healing by excellent neovascularization and promoting fast cicatricle tissue remodeling. Aim: This study aims to evaluate clinically and histologically accelerated effect of platelet-rich fibrin (PRF) membrane and PRF matrix (PRFM) following depigmentation procedure. Materials and Methods: Eleven individuals were divided into three groups after depigmentation procedure...
March 2018: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29769769/evaluation-of-periosteum-eversion-and-coronally-advanced-flap-techniques-in-the-treatment-of-isolated-miller-s-class-i-ii-gingival-recession-a-comparative-clinical-study
#18
Koel Debnath, Anirban Chatterjee
Aim: The present investigation aimed to evaluate root coverage (RC) with periosteum eversion technique (PET) using periosteum as a graft and coronally advanced flap (CAF) with platelet-rich fibrin (PRF) membrane as a graft in the treatment of isolated Miller's class I and II gingival recession defects. Materials and Methods: Thirty sites in 15 participants with Miller's Class I or II gingival recession were randomly treated either with PET using periosteum as graft and CAF + PRF as graft...
March 2018: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29768536/comparison-of-platelet-rich-plasma-versus-fibrin-glue-on-colonic-anastomoses-in-rats
#19
Yusuf Kenan Daglioglu, Ozgul Duzgun, Inanc Samil Sarici, Kemal Turker Ulutas
PURPOSE: To compare platelet rich plasma (PRP) and fibrin glue about the effect of anastomotic healing. METHODS: Thirty six Wistar-Albino male rats diveded into 3 groups according to control(Group1), PRP (Group 2) and fibrin glue(Tisseel VH) (Group 3). The colon was transected with scissor and subsequently an end to end anastomosis was performed using continuous one layer 6/0 vicryl sutures. Postoperative 7th day effect of anastomotic healing measuring with tissue hydroxyproline(TH) level and anastomotic bursting pressure(ABP); moreover comparison of cytokine (IL-6 and IL-10) and procalcitonin levels on 1st,3rd and 7th days...
April 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29768524/evaluation-of-the-effect-of-dose-dependent-platelet-rich-fibrin-membrane-on-treatment-of-gingival-recession-a-randomized-controlled-clinical-trial
#20
Rana Culhaoglu, Levent Taner, Berceste Guler
Miller's class I gingival recessions (GR) have been treated using coronally advanced flap (CAF) with platelet-rich fibrin membrane (PRF membrane) or connective tissue graft (CTG). The aim of this study was to evaluate the effect of different multiple layers of PRF membranes for the treatment of GR compared with the CTG procedure. Sixty-three Miller class I GR were treated in this study. Twenty-one GR selected randomly were treated with two layers of PRF membranes+CAF in 2PRF+CAF (test group-1), four layers of PRF membranes+CAF in 4PRF+CAF (test group-2), and CTG+CAF in the control group...
May 14, 2018: Journal of Applied Oral Science: Revista FOB
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