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https://www.readbyqxmd.com/read/29929019/the-rehabilitation-of-advanced-heart-failure-patients-after-left-ventricular-assist-device-a-narrative-review
#1
REVIEW
Sarah M Eickmeyer, Kim D Barker, Anjum Sayyad, Leslie Rydberg
As an increasing number of patients with advanced heart failure are receiving a Left Ventricular Assist Device (LVAD) as either destination therapy or bridge to transplantation, there is increasing attention on functional outcomes and quality of life after LVAD implantation. Rehabilitation providers in the acute inpatient rehabilitation setting increasingly will treat patients with LVAD and should understand the exercise physiology, medical management, rehabilitation considerations, and outcomes after rehabilitation for patients with LVAD...
June 18, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29928642/pathophysiology-and-diagnosis-of-pulmonary-hypertension-due-to-left-heart-disease
#2
REVIEW
Athanasios Charalampopoulos, Robert Lewis, Peter Hickey, Charlotte Durrington, Charlie Elliot, Robin Condliffe, Ian Sabroe, David G Kiely
Pulmonary hypertension due to left heart disease (PH-LHD) is the most common type of pulmonary hypertension, although an accurate prevalence is challenging. PH-LHD includes PH due to systolic or diastolic left ventricular dysfunction, mitral or aortic valve disease and congenital left heart disease. In recent years a new and distinct phenotype of "combined post-capillary and pre-capillary PH," based on diastolic pulmonary gradient and pulmonary vascular resistance, has been recognized. The roles of right ventricular dysfunction and pulmonary vascular compliance in PH-LHD have also been elucidated recently and they appear to have significant clinical implications...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29928523/muscle-atrophy-in-chronic-obstructive-pulmonary-disease-molecular-basis-and-potential-therapeutic-targets
#3
REVIEW
Esther Barreiro, Ariel Jaitovich
Patients with chronic obstructive pulmonary disease (COPD) experience several systemic manifestations such skeletal muscle dysfunction with and without muscle mass loss. Moreover, frequent comorbidities such as nutritional abnormalities, heart failure, and pulmonary hypertension, which are frequently associated with COPD may further contribute to skeletal muscle mass loss and dysfunction. Muscle dysfunction impairs the patients' exercise capacity and quality of life as daily life activities may be hampered by this problem...
May 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29928010/association-between-right-ventricle-two-and-three-dimensional-echocardiography-and-exercise-capacity-in-patients-with-reduced-left-ventricular-ejection-fraction
#4
Aleksandra Sljivic, Milena Pavlovic Kleut, Zoran Bukumiric, Vera Celic
INTRODUCTION: Echocardiography represents the most commonly performed noninvasive cardiac imaging test for patients with heart failure (HF). The aim of this study was to assess the relationship between exercise capacity parameters (peak oxygen consumption (VO2) and the minute ventilation-carbon dioxide production relationship (VE/VCO2)), two-dimensional speckle-tracking echocardiography (2D-STE) and three-dimensional echocardiography (3DE) imaging of right ventricular (RV) function in HF patients with reduced ejection fraction (EF)...
2018: PloS One
https://www.readbyqxmd.com/read/29926675/-effects-of-different-steps-of-brisk-walking-on-the-fitness-of-middle-aged-and-old-men
#5
Bin Fan
OBJECTIVES: To analyze the effect of walking pace on the fitness of middle-aged and elderly people in order to provide more theoretical data for the development of entensive mass fitness based on the means of sports physiological and biochemical techniques. METHODS: The selected 80 middle-aged and elderly subjects were divided into three groups:brisk walking group A ( n =30, 56.26 ±3.68 years), brisk walking group B ( n =30, 57.65 ±4.78 years), and control group C ( n =20, 55...
February 8, 2018: Chinese Journal of Applied Physiology
https://www.readbyqxmd.com/read/29926668/-effects-of-different-intensity-exercise-training-on-apoptosis-related-micrornas-and-the-targeted-proteins-in-cardiomyocytes
#6
Yong-Cai Zhao, Jin-Mei Fu, Bing-Hong Gao
OBJECTIVE: To detect the levels of miR-1, miR-21 and their targeted proteins in hearts of mice after different exercise training, and discuss potential molecular mechanism. METHODS: Male C57BL/6 mice were randomly divided to 3 groups:sedentary (SE), exercise training 1(ET1) and exercise training 2 (ET2). SE did not do any exercise; ET1 undertook swimming training for 8 weeks, once a day, 5 days/week. Swimming 30 min in the 1st week, and the duration was increased 10 min per week to 90 min and maintained in the 7th and 8th week...
January 8, 2018: Chinese Journal of Applied Physiology
https://www.readbyqxmd.com/read/29926665/-effects-of-aerobic-exercise-plus-diet-control-on-serum-levels-of-total-igf-1-and-igf-1-binding-protein-3-in-female-obese-youths-and-adolescents
#7
Hong-Fang Yang, Xiao-Jing Lin, Xiao-Hui Wang
OBJECTIVE: To investigate the effects of 4-week moderate aerobic exercise plus diet control on serum levels of total insulin-like growth factor 1(IGF-1) and IGF-1 binding protein-3 (IGFBP-3) as well as IGF-1 activity (reflected by molar ratio of IGF-1/IGFBP-3) in female obese adolescents and youths, and their possible role on fat loss, and improvement of glucose and lipid metabolism. METHODS: Nine female obese youths (age:18~19 y) and 30 female obese adolescents (age:14~16 y) were recruited and undertook 4-week aerobic exercise such as swimming and jogging (6 days/week, twice a day, 2 h/time with 5 min rest per 30 min exercise) with gradual increase of intensity from low (heart rate immediately post-exercise of 1st week:100~120 beats/min) to moderate (heart rate immediately post-exercise of 2nd -4th weeks:120~140 beats/min) level, combined with a diet intervention (total daily energy intake of 1 400 or 1 600 kcal according to basal metabolism rate) in Shanghai Dianfeng weight loss enclosed camp...
January 8, 2018: Chinese Journal of Applied Physiology
https://www.readbyqxmd.com/read/29926654/-current-status-of-blood-pressure-control-in-patients-with-coronary-heart-disease
#8
Yue Zhang, Tian-Tian Wang, Shu-Li Guo, Li-Na Han, Li Zhang, Xiao-Ying Li, Jin Fan
OBJECTIVE: To evaluate the level of blood pressure control in patients with coronary heart disease (CHD) of China in order to provide guidance for the prevention and treatment of CHD. METHODS: The patients with CHD were retrospectively collected from 2011~2014 in PLA General Hospital and Hainan Branch Hospital. Then analyzed the difference of blood pressure compliance rate between different surgical methods percutaneous coronary intervention (PCI), coronary artery bypass grafting(CABG), secondary preventive drugs(aspirin, clopidogrel, nitrates, trimetazidine, nicorandil, hypotensor, hypoglycemic, lipid-lowering drugs) and lifestyle(smoking, drinking, exercise)...
January 8, 2018: Chinese Journal of Applied Physiology
https://www.readbyqxmd.com/read/29926282/heart-rate-during-exercise-mechanisms-behavior-and-therapeutic-and-prognostic-implications-in-heart-failure-patients-with-reduced-ejection-fraction
#9
REVIEW
Stefania Paolillo, Piergiuseppe Agostoni, Fabiana De Martino, Francesca Ferrazzano, Fabio Marsico, Paola Gargiulo, Elisabetta Pirozzi, Caterina Marciano, Santo Dellegrottaglie, Pasquale Perrone Filardi
Exercise intolerance is a typical manifestation of patients affected by heart failure with reduced ejection fraction (HFrEF); however, the relationship among functional capacity, mortality, and exercise-induced heart rate response during exercise remains unclear in either sinus rhythm or atrial fibrillation subjects. Heart rate increase during incremental load exercise has a typical pattern in normal subjects, whereas it is commonly compromised in HFrEF patients, mainly due to the imbalance of the autonomic nervous system...
July 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29925711/interactive-effect-of-rehydration-with-diluted-sports-drink-and-water-gargling-on-salivary-flow-ph-and-buffering-capacity-during-ergometer-exercise-in-young-adult-volunteers
#10
Mai Tanabe-Ikegawa, Toshiyuki Takahashi, Hiroshi Churei, Akihiro Mitsuyama, Toshiaki Ueno
The present study was conducted to investigate the influence of rehydration with diluted sports drink and water gargling on salivary flow, pH and buffering capacity during exercise. Nineteen participants performed a 30-min bicycle ergometer exercise at 80% of maximal heart rate while consuming a sports drink, followed by gargling with water, or no gargling, immediately after the exercise (Exp. 1). The same experiment was then conducted on 9 participants who drank 1.5-fold diluted sports drink (Exp. 2-A) and 10 who drank 2-fold diluted sports drink (Exp...
2018: Journal of Oral Science
https://www.readbyqxmd.com/read/29925691/pan-ampk-activator-o304-improves-glucose-homeostasis-and-microvascular-perfusion-in-mice-and-type-2-diabetes-patients
#11
Pär Steneberg, Emma Lindahl, Ulf Dahl, Emmelie Lidh, Jurate Straseviciene, Fredrik Backlund, Elisabet Kjellkvist, Eva Berggren, Ingela Lundberg, Ingela Bergqvist, Madelene Ericsson, Björn Eriksson, Kajsa Linde, Jacob Westman, Thomas Edlund, Helena Edlund
AMPK activated protein kinase (AMPK), a master regulator of energy homeostasis, is activated in response to an energy shortage imposed by physical activity and caloric restriction. We here report on the identification of PAN-AMPK activator O304, which - in diet-induced obese mice - increased glucose uptake in skeletal muscle, reduced β cell stress, and promoted β cell rest. Accordingly, O304 reduced fasting plasma glucose levels and homeostasis model assessment of insulin resistance (HOMA-IR) in a proof-of-concept phase IIa clinical trial in type 2 diabetes (T2D) patients on Metformin...
June 21, 2018: JCI Insight
https://www.readbyqxmd.com/read/29923110/effects-of-a-short-term-aquatic-exercise-intervention-on-symptoms-and-exercise-capacity-in-individuals-with-chronic-fatigue-syndrome-myalgic-encephalomyelitis-a-pilot-study
#12
Suzanne Broadbent, Sonja Coetzee, Rosalind Beavers
PURPOSE: This pilot pre-and post-intervention study investigated the effects of a short-term aquatic exercise programme on physiological outcomes, symptoms and exercise capacity in women with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). METHODS: Eleven women (54.8 ± 12.4 year) volunteered for the 5-week program; an initial 20-min aquatic exercise session then two self-paced 20-min sessions per week for 4 weeks. Pre- and post-intervention outcomes were physiological measures, 6 min Walk Test (6MWT), perceived exertion (RPE), hand grip strength, Sit-to-Stand, Sit-Reach test, Apley's shoulder test, FACIT questionnaire, and 24-h post-test tiredness and pain scores (0-10 visual analogue scale)...
June 19, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29922729/the-heart-score-a-guide-to-its-application-in-the-emergency-department
#13
REVIEW
William Brady, Katya de Souza
Chest pain is one of the most common, potentially serious presenting complaints for adult emergency department (ED) visits. The challenge of acute coronary syndrome (ACS) identification with appropriate disposition is quite significant. Many of these patients are low risk and can be managed non-urgently in the outpatient environment; other patients, however, are intermediate to high risk for ACS and should be managed more aggressively, likely with inpatient admission and cardiology consultation. The HEART score, a recently derived clinical decision rule aimed at the identification of risk in the undifferentiated chest pain patient, is potentially quite useful as an adjunct to physician medical decision-making...
June 2018: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29922179/peripheral-resistance-baroreflex-during-incremental-bicycle-ergometer-exercise-characterization-and-correlation-with-cardiac-baroreflex
#14
Alberto Porta, Vlasta Bari, Beatrice De Maria, Beatrice Cairo, Emanuele Vaini, Mara Malacarne, Massimo Pagani, Daniela Lucini
The arm of the baroreflex (BR) controlling peripheral resistances (PR), labeled as BR of PR (prBR), was characterized through an extension of the cardiac BR (cBR) sequence analysis. The method exploits recordings of skin blood flow (SBF) from the palm of the non-dominant hand via a laser Doppler flowmeter and of arterial pressure (AP) from the middle finger of the same hand via a plethysmographic device. PR was estimated beat-by-beat as the ratio of mean AP to mean SBF computed over the same heart period (HP)...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29921963/chocolate-milk-for-recovery-from-exercise-a-systematic-review-and-meta-analysis-of-controlled-clinical-trials
#15
REVIEW
Mojgan Amiri, Reza Ghiasvand, Mojtaba Kaviani, Scott C Forbes, Amin Salehi-Abargouei
BACKGROUND/OBJECTIVES: Chocolate milk (CM) contains carbohydrates, proteins, and fat, as well as water and electrolytes, which may be ideal for post-exercise recovery. We systematically reviewed the evidence regarding the efficacy of CM compared to either water or other "sport drinks" on post-exercise recovery markers. SUBJECTS/METHODS: PubMed, Scopus, and Google scholar were explored up to April 2017 for controlled trials investigating the effect of CM on markers of recovery in trained athletes...
June 19, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29920702/false-positive-stress-testing-does-endothelial-vascular-dysfunction-contribute-to-st-segment-depression-in-women-a-pilot-study
#16
Shilpa Sharma, Puja K Mehta, Reza Arsanjani, Tara Sedlak, Zachary Hobel, Chrisandra Shufelt, Erika Jones, Paul Kligfield, David Mortara, Michael Laks, Marcio Diniz, C Noel Bairey Merz
BACKGROUND: The utility of exercise-induced ST-segment depression for diagnosing ischemic heart disease (IHD) in women is unclear. HYPOTHESIS: Based on evidence that IHD pathophysiology in women involves coronary vascular dysfunction, we hypothesized that coronary vascular dysfunction contributes to exercise electrocardiography (Ex-ECG) ST-depression in the absence of obstructive CAD, so-called "false positive" results. We tested our hypothesis in a pilot study evaluating the relationship between peripheral vascular endothelial function and Ex-ECG...
June 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29916576/validity-and-reliability-of-textile-system-sensoria-for-posturographic-measurements
#17
Giovanni D'Addio, Luigi Iuppariello, Paolo Bifulco, Bernardo Lanzillo, Nicola Pappone, Mario Cesarelli
OBJECTIVES: Smart fabrics and interactive textiles are a relatively new area of research, with many potential applications in the field of biomedical engineering. The ability of smart textiles to interact with the body provides a novel means to sense the wearer's physiology and respond to the needs of the wearer. Physiological signals, such as heart rate, breathing rates, and activity levels, are useful indicators of health status. These signals can be measured by means of textile-based sensors integrated into smart clothing which has the ability to keep a digital record of the patient's physiological responses since his or her last clinical visit, allowing doctors to make a more accurate diagnosis...
December 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29916025/short-term-weight-loss-reverses-obesity-induced-microvascular-endothelial-dysfunction
#18
Tamas Csipo, Gabor A Fulop, Agnes Lipecz, Stefano Tarantini, Tamas Kiss, Priya Balasubramanian, Anna Csiszar, Zoltan Ungvari, Andriy Yabluchanskiy
Obesity is one of the major risk factors for cardiovascular diseases and its prevalence is increasing in all age groups, with the biggest impact observed in middle-aged and older adults. A critical mechanism by which obesity promotes vascular pathologies in these patients involves impairment of endothelial function. While endothelial dysfunction in large vessels promotes atherogenesis, obesity-induced microvascular endothelial dysfunction impairs organ perfusion and thereby is causally related to the pathogenesis of ischemic heart disease, chronic kidney disease, intermittent claudication, exercise intolerance, and exacerbates cognitive decline in aging...
June 18, 2018: GeroScience
https://www.readbyqxmd.com/read/29914307/a-mathematical-modelling-analysis-of-the-response-of-blood-pressure-and-heart-rate-to-submaximal-exercise
#19
Elena Ioana Iconaru, Luminita Georgescu, Constantin Ciucurel
OBJECTIVE: According to Golden ratio (GR) and Fibonacci sequence, models of the organisation of various structures can be encountered in biology, medicine, architecture and engineering. Recent studies indicate that GR can be highlighted in the organisation and physiological functioning of the cardiovascular system. The aim of this study was to investigate the cardiovascular homeostasis during rest and exercise testing by determining the GR validity at the dynamic level of systolic and diastolic blood pressure (SBP, DBP) and heart rate (HR) values...
June 18, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29912082/match-play-running-performance-and-exercise-intensity-in-elite-international-women-s-rugby-sevens
#20
Shane Malone, Marian Earls, Aidan Shovlin, Anthony Eddy, Nick Winkelman
Malone, S, Earls, M, Shovlin, A, Eddy, A, and Winkleman, N. Match-play running performance and exercise intensity in elite international women's rugby sevens. J Strength Cond Res XX(X): 000-000, 2018-The aim of the current investigation was to describe the running and physiological performance demands of elite women's rugby sevens match-play. Twenty-seven (n = 27) rugby seven's players (24.4 ± 2.1 years; 168 ± 7.1 cm; 67.9 ± 4.3 kg) were recruited for the current investigation. Across the observational period, 36 games were analyzed; during these games, players wore global positioning system technology (10-Hz, Statsports Viper Pod; STATSports, Newry, Northern Ireland, United Kingdom) and heart rate monitors (Polar Team System, Polar Electro Oy, Kempele, Finland)...
June 14, 2018: Journal of Strength and Conditioning Research
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