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Exercise and heart

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https://www.readbyqxmd.com/read/29458113/poorer-positive-affect-in-response-to-self-paced-exercise-among-the-obese
#1
Hassan M Elsangedy, Paulo H D Nascimento, Daniel G S Machado, Kleverton Krinski, Sarah J Hardcastle, Sérgio G DaSilva
We aimed to investigate the association between body mass index (BMI) and affective response, ratings of perceived exertion (RPE), and physiological responses during self-paced exercise. Sixty-six women were divided into three groups accordingly with the BMI: obese (n = 22: 33.5 ± 8.5 yr; 34.9 ± 4.1 kg∙m-2 ), overweight (n = 22: 34.8 ± 8.6 yr; 26.4 ± 1.3 kg∙m-2 ), and normal-weight (n = 22: 30.8 ± 9.3 yr; 22.0 ± 1.6 kg∙m-2 ). They underwent a graded exercise test and a 20-min self-paced walking session on a treadmill...
February 16, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29457257/pharmacokinetics-pharmacodynamics-and-metabolism-of-acepromazine-following-intravenous-oral-and-sublingual-administration-to-exercised-thoroughbred-horses
#2
H K Knych, K Seminoff, D S McKemie, P H Kass
Acepromazine is a tranquilizer used commonly in equine medicine. This study describes serum and urine concentrations and the pharmacokinetics and pharmacodynamics of acepromazine following intravenous, oral, and sublingual (SL) administration. Fifteen exercised adult Thoroughbred horses received a single intravenous, oral, and SL dose of 0.09 mg/kg of acepromazine. Blood and urine samples were collected at time 0 and at various times for up to 72 hr and analyzed for acepromazine and its two major metabolites (2-(1-hydroxyethyl) promazine and 2-(1-hydroxyethyl) promazine sulfoxide) using liquid chromatography-tandem mass spectrometry...
February 18, 2018: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29457223/programming-repercussions-of-early-life-training-exercise-on-the-heart
#3
Gustavo Davanzo, Matheus Fragas
Almost thirty years ago the term programming was first used by Lucas (1991) to describe that the influence of nutrition stimuli during important phases of preterm development has future consequences in the organism's health. This article is protected by copyright. All rights reserved.
February 18, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29456025/effectiveness-of-user-and-expert-driven-web-based-hypertension-programs-an-rct
#4
Sam Liu, Dina Brooks, Scott G Thomas, Gunther Eysenbach, Robert P Nolan
INTRODUCTION: The effectiveness of self-guided Internet-based lifestyle counseling (e-counseling) varies, depending on treatment protocol. Two dominant procedures in e-counseling are expert- and user-driven. The influence of these procedures on hypertension management remains unclear. The objective was to assess whether blood pressure improved with expert-driven or user-driven e-counseling over control intervention in patients with hypertension over a 4-month period. STUDY DESIGN: This study used a three-parallel group, double-blind randomized controlled design...
February 15, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29455794/effect-of-ventricular-function-and-volumes-on-exercise-capacity-in-adults-with-repaired-tetralogy-of-fallot
#5
Natalia Dłużniewska, Piotr Podolec, Tomasz Miszalski-Jamka, Maciej Krupiński, Paweł Banyś, Małgorzata Urbańczyk, Bogdan Suder, Grzegorz Kopeć, Maria Olszowska, Lidia Tomkiewicz-Pająk
OBJECTIVES: Investigate the effects of left and right ventricular function and severity of pulmonary valve regurgitation, quantified by cardiac magnetic resonance (CMR), on exercise tolerance in adult patients who underwent ToF repair at a young age. METHODS: This is a retrospective cohort study of 52 patients after ToF surgery and 33 age- and sex-matched healthy volunteers. CMR and cardiopulmonary exercise testing (CPET) were performed on all patients; CPET was performed on control subjects...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29454783/comparison-of-the-diastolic-stress-test-with-a-combined-resting-echocardiography-and-biomarker-approach-to-patients-with-exertional-dyspnea-diagnostic-and-prognostic-implications
#6
Wojciech Kosmala, Monika Przewlocka-Kosmala, Aleksandra Rojek, Thomas H Marwick
OBJECTIVES: This study sought to establish the diagnostic and prognostic value of a strategy for prediction of abnormal diastolic response to exercise (AbnDR) using clinical, biochemical, and resting echocardiographic markers in dyspneic patients with mild diastolic dysfunction. BACKGROUND: An AbnDR (increase in left ventricular filling pressure) may indicate heart failure with preserved ejection fraction as the cause of symptoms in dyspneic patients, despite a nonelevated noncardiac at rest...
February 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29454775/left-ventricular-dysfunction-and-exercise-capacity-trajectory-implications-for-subclinical-heart-failure-staging-criteria
#7
Julian W Sacre, Chiew Wong, Yih-Kai Chan, Melinda J Carrington, Simon Stewart, Bronwyn A Kingwell
OBJECTIVES: This study aimed to determine the association of stage B heart failure (SBHF) and its constituent left ventricular (LV) abnormalities with trajectory of exercise capacity over time, and assess whether this association is modified by reversion of these LV abnormalities to normal. BACKGROUND: The LV abnormalities of SBHF may coincide with a reduction in exercise capacity that precedes the overt exercise intolerance of clinical heart failure (HF). Determining the predictive capacity of established and novel SBHF criteria for exercise capacity decline may improve HF risk stratification...
February 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29454772/decreased-exercise-tolerance-in-stage-b-heart-failure-a-shade-of-grey
#8
EDITORIAL
Thierry C Gillebert
No abstract text is available yet for this article.
February 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29453755/effect-of-nicotine-on-repeated-bouts-of-anaerobic-exercise-in-nicotine-na%C3%A3-ve-individuals
#9
Robert Johnston, Melissa Crowe, Kenji Doma
PURPOSE: Nicotine is a psychostimulant that is reported to be commonly supplemented by athletes. The purpose of the current study was to determine the effects of a rapidly absorbed form of nicotine on repeated bouts of anaerobic exercise, perception of exertion and a range of cardiovascular variables while monitoring side effect profiles. METHODS: Sixteen healthy, nicotine naïve male athletes (24.1 ± 5.3 years, 179.0 ± 8.8 cm, 81.7 ± 13.5 kg, BMI 25.5 ± 3.0, Body fat% 13...
February 16, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29453746/effect-of-aerobic-exercise-on-treg-and-th17-of-rats-with-ischemic-cardiomyopathy
#10
Zhisong Chen, Wenwen Yan, Yu Mao, Yi Ni, Lin Zhou, Haoming Song, Wenjun Xu, Leming Wang, Yuqin Shen
Immune activation and inflammation participate in the progression of chronic heart failure (CHF). Th17 cells and CD4+CD25+ regulatory T (Treg) cells both come from naive Th cells and share reciprocal development pathways but exhibit opposite effects. We hypothesized that the Th17/Treg balance was impaired in patients with CHF, and exercise can improve it. Rats with ischemic cardiomyopathy were prepared by ligaturing the left anterior descending branch of the left coronary artery. Rats in training group were trained with treadmill; Th17 cells increased significantly while Treg cells significantly decreased in s by flow cytometry, and the peripheral blood level of IL-6, IL-17, and TNF-α was obviously elevated by ELISA assay...
February 16, 2018: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/29453669/physical-training-and-cardiac-rehabilitation-in-heart-failure-patients
#11
Cesare de Gregorio
Regardless of advances in medical and interventional treatment of cardiovascular disease (CVD), a limited number of patients attend a cardiac rehabilitation (CR) programme on a regular basis. Due to modern therapies more individuals will be surviving an acute cardiovascular event, but the expected burden of chronic heart failure will be increasing worldwide.However, both in high- and low-income countries, secondary prevention after an acute myocardial infarction or stroke has been implemented in less than a half of eligible patients...
February 17, 2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29450240/improving-cerebral-oxygenation-cognition-and-autonomic-nervous-system-control-of-a-chronic-alcohol-abuser-through-a-three-month-running-program
#12
Daniel Aranha Cabral, Kell Grandjean da Costa, Alexandre Hideki Okano, Hassan Mohamed Elsangedy, Vanessa Paula Rachetti, Eduardo Bodnariuc Fontes
The abusive use of alcohol has shown to be associated to cerebral damage, impaired cognition, poor autonomic nervous control, impaired cardiovascular health, increased levels of stress and anxiety, depression symptoms and poor quality of life. Aerobic exercise has shown to be an efficient tool to reduce and overcome these issues. In this case report, a patient (forty-four years old, male) under treatment in public psychiatric hospital, classified as having a substance use disorder, underwent a three-month running program...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29449412/hemodynamic-characteristics-in-significant-symptomatic-and-asymptomatic-primary-mitral-valve-regurgitation-at-rest-and-during-exercise
#13
Rine Bakkestrøm, Ann Banke, Nicolaj L Christensen, Redi Pecini, Akhmadjon Irmukhamedov, Mads Andersen, Barry A Borlaug, Jacob E Møller
BACKGROUND: In severe asymptomatic primary mitral valve regurgitation without risk factors, surgery strategy is controversial. We sought to clarify whether being symptomatic corresponds to the hemodynamic burden and reduced exercise capacity. A better understanding of this may contribute to optimize timing of surgery. METHODS AND RESULTS: Subjects with asymptomatic (New York Heart Association functional class I, n=29) or symptomatic (New York Heart Association functional class II and III, n=28) significant primary mitral valve regurgitation (effective regurgitant orifice, ≥0...
February 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29449367/load-independent-systolic-and-diastolic-right-ventricular-function-in-heart-failure-with-preserved-ejection-fraction-as-assessed-by-resting-and-handgrip-exercise-pressure-volume-loops
#14
Karl-Philipp Rommel, Maximilian von Roeder, Christian Oberueck, Konrad Latuscynski, Christian Besler, Stephan Blazek, Thomas Stiermaier, Karl Fengler, Volker Adams, Marcus Sandri, Axel Linke, Gerhard Schuler, Holger Thiele, Philipp Lurz
BACKGROUND: Although systolic right ventricular (RV) dysfunction has been shown to be a potent predictor for adverse outcomes in patients with heart failure with preserved ejection fraction (HFpEF), RV functional abnormalities in the course of the syndrome are not well characterized. We, therefore, sought to assess load-independent and load-dependent systolic and diastolic characteristics of RV function in stable outpatients with HFpEF. METHODS AND RESULTS: We invasively obtained RV and left ventricular pressure-volume loops in 24 HFpEF patients and 9 patients without heart failure symptoms with a conductance catheter during basal conditions and handgrip exercise...
February 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29449080/influence-of-exercise-modality-on-cardiac-parasympathetic-and-sympathetic-indices-during-post-exercise-recovery
#15
Scott Michael, Ollie Jay, Kenneth S Graham, Glen M Davis
OBJECTIVES: This study investigated indirect measures of post-exercise parasympathetic reactivation (using heart-rate-variability, HRV) and sympathetic withdrawal (using systolic-time-intervals, STI) following upper- and lower-body exercise. DESIGN: Randomized, counter-balanced, crossover. METHODS: 13 males (age 26.4±4.7years) performed maximal arm-cranking (MAX-ARM) and leg-cycling (MAX-LEG). Subsequently, participants undertook separate 8-min bouts of submaximal HR-matched exercise of each mode (ARM and LEG)...
February 12, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29447741/the-burden-of-iron-deficiency-in-heart-failure-therapeutic-approach
#16
REVIEW
Bruno M L Rocha, Gonçalo J L Cunha, Luiz F Menezes Falcão
Heart failure (HF) is highlighted by its burdening symptom-limited exercise capacity and recurrent hospitalizations. Despite substantial advances regarding disease-modifying drugs in HF with reduced ejection fraction, additional therapeutic strategies to improve quality of life are invaluable. Currently, iron deficiency (ID) is overwhelmingly recognized in over 30% to 50% of patients with stable chronic HF, which worsens prognosis. The established pathophysiological mechanisms of progressive HF may be intertwined with increasing myocardial iron scarcity, wherein one begets the other...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29447379/acute-exercise-is-not-cardioprotective-and-may-induce-apoptotic-signalling-in-heart-surgery-a-randomized-controlled-trial
#17
Benedikte T Smenes, Fredrik H Bækkerud, Katrine H Slagsvold, Erlend Hassel, Martin Wohlwend, Maria Pinho, Morten Høydal, Ulrik Wisløff, Øivind Rognmo, Alexander Wahba
OBJECTIVES: During open-heart surgery, the myocardium experiences ischaemia-reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia-reperfusion injury in rats, but this has never been investigated in humans. We aimed to investigate whether 1 bout of moderate exercise 24 h prior to surgery protects against mitochondrial and cardiac damage. METHODS: Patients scheduled for elective coronary artery bypass were eligible for this pilot study...
February 13, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29446507/technical-determinants-of-biathlon-standing-shooting-performance-before-and-after-race-simulation
#18
Simo Ihalainen, Marko S Laaksonen, Sami Kuitunen, Antti Leppävuori, Jussi Mikkola, Stefan Josef Lindinger, Vesa Linnamo
The aim of this study was to identify performance determining factors in biathlon standing shooting in rest and after intense exercise. Eight Finnish national and nine junior team biathletes participated in the study. Participants fired 40 resting shots (REST) and 2*5 competition simulation shots (LOAD) after 5 min of roller skiing at 95% of peak heart rate. Hit percentage, aiming point trajectory and postural balance were measured from each shot. Cleanness of triggering (ATV, movement of the aiming point 0-0...
February 15, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29446206/regression-equations-to-estimate-the-2-min-walk-distance-in-an-adult-asian-population-aged-40-75-years
#19
Fatim T Mirza, Sue Jenkins, Maria Justine, Nola Cecins, Kylie Hill
BACKGROUND AND OBJECTIVE: There is increased use of the 2-min walk test (2MWT) to assess functional exercise capacity. However, the distance achieved during this test may be difficult to interpret in the absence of reference values from a local population. Regression equations to estimate the 2-min walk distance (2MWD) only exist for American and Brazilian populations. The objective of this study was to develop regression equations to estimate the 2MWD in Malaysian adults who were free from major health problems...
February 14, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29444414/no-individual-or-combined-effects-of-caffeine-and-beetroot-juice-supplementation-during-submaximal-or-maximal-running
#20
Johanna Oskarsson, Kerry McGawley
BACKGROUND: Dietary supplements such as caffeine and beetroot juice are used by athletes in an attempt to optimize performance and therefore gain an advantage in competition. AIM: To investigate the individual and combined effects of caffeine and beetroot-juice supplementation during submaximal and maximal treadmill running. METHODS: Seven males (VO<sub>2max</sub>: 59.0 ± 2.9 mL/kg/min) and two females (VO<sub>2max</sub>: 53...
February 14, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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