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https://www.readbyqxmd.com/read/29774988/differences-in-primary-cardiovascular-disease-prevention-between-the-2013-and-2016-cholesterol-guidelines-and-impact-of-the-2017-hypertension-guideline-in-the-united-states
#1
Brent M Egan, Jiexiang Li, Robert A Davis, Kevin A Fiscella, Jonathan N Tobin, Daniel W Jones, Angelo Sinopoli
The US Preventive Services Task Force cholesterol guideline recommended statins for fewer adults than the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline by setting a higher 10-year atherosclerotic cardiovascular disease threshold (≥10.0% vs ≥7.5%) and requiring concomitant diabetes mellitus, hypertension, dyslipidemia, or cigarette smoking. The 2017 ACC/AHA hypertension guideline lowered the hypertension threshold, increasing 2016 guideline statin-eligible adults. Cross-sectional data on US adults aged 40 to 75 years enabled estimated numbers for the 2013 guideline and 2016 guideline with hypertension thresholds of ≥140/≥90 mm Hg and ≥130/80 mm Hg, respectively, on: (1) untreated, statin-eligible adults for primary atherosclerotic cardiovascular disease prevention (25...
May 18, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29773412/athlete-s-heart-is-the-morganroth-hypothesis-obsolete
#2
Mark J Haykowsky, T Jake Samuel, Michael D Nelson, Andre La Gerche
In 1975, Morganroth and colleagues reported that the increased left ventricular (LV) mass in highly trained endurance athletes versus nonathletes was primarily due to increased end-diastolic volume while the increased LV mass in resistance trained athletes was solely due to an increased LV wall thickness. Based on the divergent remodelling patterns observed, Morganroth and colleagues hypothesised that the increased "volume" load during endurance exercise may be similar to that which occurs in patients with mitral or aortic regurgitation while the "pressure" load associated with performing a Valsalva manoeuvre (VM) during resistance exercise may mimic the stress imposed on the heart by systemic hypertension or aortic stenosis...
May 1, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29769492/relationship-between-triglyceride-and-hdl-c-ratio-with-acute-coronary-syndrome
#3
M Z Islam, M N Islam, T K Bhowmik, B Saha, M S Hossain, H Ahmed, M S Ali, S S Shakil, P K Paul
Cardiovascular diseases (CVD) is the leading cause of death worldwide, responsible for one third of death, coronary artery disease (CAD) is the most common cause. Dyslipidaemiais one of the major contributors increased of CAD risk. This study was aimed to find out the relationship between triglyceride and HDL cholesterol ratio with acute coronary syndrome. This cross sectional study was conducted in the department of Cardiology, Mymensingh Medical College Hospital from August 2009 to May 2010. Smoking, hypertension, serum total cholesterol level, serum HDL-C, LDL-C, triglyceride (TG) level were important variable considered...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769489/pattern-of-disease-among-patients-attending-cardiology-outpatient-department-of-a-private-hospital-of-mymensingh-bangladesh
#4
G K Paul, B Sen, M K Khan, T K Bhowmik, T A Khan, A K Roy
Epidemiologic transition is taking place in every part of the world. Cardiovascular diseases became the most common cause of death accounting for 30% of deaths worldwide, with 80% of the burden now occurring in developing countries. The objective of the study was to assess the Pattern of disease among patients attending Cardiology outpatient department of a private hospital. The cross sectional descriptive type of observational study was conducted among 550 patients attending Cardiology outpatient department (COPD) of Sodesh Hospital, Mymensingh, Bangladesh from March 2016 to June 2016...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29767575/dart-to-the-target-an-alternative-bull-s-eye-parametric-display-for-european-society-of-cardiology-european-respiratory-society-goal-oriented-risk-reduction-strategy-in-pulmonary-arterial-hypertension
#5
Cihangir Kaymaz, Ozgur Yasar Akbal, Aykun Hakgor, Hacer Ceren Tokgoz, Seda Tanyeri
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29759801/-evaluation-of-the-prescription-of-furosemide-in-persons-aged-75years-and-older-in-a-geriatric-acute-care-unit
#6
M Buttard, A Putot, P d'Athis, L Pioro, S Asgassou, S Putot, M Deïdda, C Laborde, M Dipanda, R Mahmoudi, P Manckoundia
INTRODUCTION: Furosemide is very often prescribed in France. It may cause important adverse effects especially in elderly persons. In order to limit its misuse and excessive expenditure for health insurance organizations, the European Society of Cardiology drafted strict guidelines for its prescription. We conducted a study in this population to determine the rate of prescription of furosemide in elderly persons outside the guidelines. METHOD: This was a prospective, single-centre, observational study bearing on elderly persons aged 75years and more admitted to a geriatric acute-care unit over a period of 6months...
May 11, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29755623/main-considerations-of-cardiogenic-shock-and-its-predictors-systematic-review
#7
REVIEW
Maria Christiane Valeria Braga Braile-Sternieri, Eliana Migliorini Mustafa, Victor Rodrigues Ribeiro Ferreira, Sofia Braile Sabino, Giovanni Braile Sternieri, Lucia Angelica Buffulin de Faria, Bethina Canaroli Sbardellini, Cibele Olegario Vianna Queiroz, Domingo Marcolino Braile, Idiberto Jose Zotarelli Filho
The mortality rate of post-infarction cardiogenic shock (CS) was 80.0-90.0%. Recent studies show a significant reduction of hospital mortality to approximately 50.0%. CS is defined as systemic tissue hypoperfusion resulting from systolic and/or diastolic heart dysfunction, the main cause of which is acute myocardial infarction (AMI). The main predictors are biological markers such as troponin, CKMB and lactate. A systematic literature review and meta-analysis is performed in order to present and correlate the main literary findings on CS and its evolution with possible changes in biomarkers such as troponin, lactate and CKMB...
April 2018: Cardiology Research
https://www.readbyqxmd.com/read/29753425/-the-contribution-of-systematic-implementation-of-cardiovascular-explorations-for-the-detection-of-cardiac-sources-of-embolism-in-patients-with-stroke-about-230-patients
#8
A Hadi, L Bendriss, A Khatouri
OBJECTIVES: Ischemic stroke are estimated at 80% of all strokes. Embolism of cardiac origin accounts for around 20% of them. The aim of our study is to report the contribution of cardiovascular investigations performed as a routine during the evaluation of patients with ischemic stroke. PATIENTS AND METHODS: This is a retrospective study of ischemic stroke cases collated in Cardiology department of the military hospital of Marrakech between January 2010 and December 2014...
May 9, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29743995/percutaneous-repair-of-mitral-regurgitation
#9
REVIEW
Colin M Barker
Mitral regurgitation (MR) affects more than 2 million people in the United States annually and is the second leading cause of heart valve disease after aortic stenosis. Surgical intervention is the currently accepted treatment of choice in patients with either symptomatic degenerative MR or asymptomatic MR with pulmonary hypertension, atrial fibrillation, or left ventricular dysfunction. Based on robust evidence from clinical trials, the MitraClip Transcatheter Mitral Valve Repair system (Abbott Vascular) was approved in the United States for commercial use in 2013...
July 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29731025/the-2017-american-college-of-cardiology-american-heart-association-vs-hypertension-canada-high-blood-pressure-guidelines-and-potential-implications
#10
Rémi Goupil, Maxime Lamarre-Cliche, Michel Vallée
In this report we examine the differences between the 2017 Hypertension Canada and 2017 American College of Cardiology and American Heart Association (ACC/AHA) blood pressure (BP) guidelines regarding the proportions of individuals with a diagnosis of hypertension, BP above thresholds for treatment initiation, and BP below targets using the CARTaGENE cohort. Compared with the 2017 Canadian guidelines, the 2017 ACC/AHA guidelines would result in increases of 8.7% in hypertension diagnosis and 3.4% of individuals needing treatment, with 17...
May 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29729173/indscators-of-blood-lipid-profile-acute-phase-reactions-and-uric-acid-in-patients-with-arterial-hypertension-combined-with-connective-tissue-dysplasia
#11
Yevheniya H Zaremba, Nataliya O Rak, Olha V Zaremba, Olena V Zaremba-Fedchyshyn, Marianna M Virna, Liliya O Odnorih
OBJECTIVE: Introduction:Changes in the cardiovascular system can be divided into 2 groups due to the connective tissue dysplasia (CTD) and changes in the circulatory system, caused by pathological processes that arose on the basis of the connective structures failure. One of the risk factors of arterial hypertension (AH) remaining insufficiently studied is collagen pathology - nondifferentiated connective tissue dysplasia (NCTD). The presence of connective tissue in all organs and systems, the common origin of smooth muscles, blood and lymph from mesenchyma leads to dysplastic changes in any organ and system...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29728831/time-trends-in-characteristics-clinical-course-and-outcomes-of-13-791-patients-with-acute-heart-failure
#12
Pere Llorens, Patricia Javaloyes, Francisco Javier Martín-Sánchez, Javier Jacob, Pablo Herrero-Puente, Víctor Gil, José Manuel Garrido, Eva Salvo, Marta Fuentes, Héctor Alonso, Fernando Richard, Francisco Javier Lucas, Héctor Bueno, John Parissis, Christian E Müller, Òscar Miró
OBJECTIVES: To analyse time trends in patient characteristics, clinical course, hospitalisation rate, and outcomes in acute heart failure along a 10-year period (2007-2016). METHODS: The EAHFE registry has prospectively collected 13,971 consecutive AHF patients diagnosed in 41 Spanish emergency departments (EDs) at five different time points (2007/2009/2011/2014/2016). Eighty patient-related variables and outcomes were described and statistically significant changes along time were evaluated...
May 4, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29727376/cardiovascular-disease-risk-among-older-immigrants-in-the-united-states-a-comparison-of-risk-measures
#13
Tina R Sadarangani, Deborah Chyun, Chau Trinh-Shevrin, Gary Yu, Christine Kovner
BACKGROUND: In the United States, 16 million immigrants are 50 years and older, but little is known about their cardiometabolic health and how to best assess their cardiovascular disease (CVD) risk. Aging immigrants may therefore not be benefitting from advances in CVD prevention. OBJECTIVE: In this study, we estimate and compare CVD risk in a nationally representative sample of aging immigrants using 3 different measures. METHODS: This was a cross-sectional analysis using National Health and Nutrition Examination Survey data...
April 27, 2018: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29726985/expert-consensus-document-on-the-management-of-hyperkalaemia-in-patients-with-cardiovascular-disease-treated-with-raas-inhibitors-coordinated-by-the-working-group-on-cardiovascular-pharmacotherapy-of-the-european-society-of-cardiology
#14
Giuseppe M C Rosano, Juan Tamargo, Keld P Kjeldsen, Mitja Lainscak, Stefan Agewall, Stefan D Anker, Claudio Ceconi, Andrew J S Coats, Heinz Drexel, Gerasimos Filippatos, Juan Carlos Kaski, Lars Lund, Alexander Niessner, Gianluigi Savarese, Thomas A Schmidt, Petar Seferovic, Sven Wassmann, Thomas Walther, Basil S Lewis
Renin angiotensin aldosterone system inhibitors/antagonists/blockers (RAASi) are a cornerstone in treatment of patients with cardiovascular diseases especially in those with heart failure (HF) due to their proven effect on surrogate and hard end-points. RAASi are also the basis in treatment of arterial hypertension and they are furthermore indicated to reduce events and target organ damage in patients with diabetes and chronic kidney disease, where they have specific indication because of the evidence of benefit...
May 3, 2018: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/29724385/sildenafil-added-to-pirfenidone-in-patients-with-advanced-idiopathic-pulmonary-fibrosis-and-risk-of-pulmonary-hypertension-a-phase-iib-randomised-double-blind-placebo-controlled-study-rationale-and-study-design
#15
Jürgen Behr, Steven D Nathan, Sergio Harari, Wim Wuyts, Klaus-Uwe Kirchgaessler, Monica Bengus, Frank Gilberg, Athol U Wells
BACKGROUND: Pulmonary hypertension (PH) is commonly observed in patients with advanced idiopathic pulmonary fibrosis (IPF). Despite the availability of therapies for both IPF and PH, none are approved for PH treatment in the context of significant pulmonary disease. This study will investigate the use of sildenafil added to pirfenidone in patients with advanced IPF and risk of PH, who represent a group with a high unmet medical need. METHODS: This Phase IIb, randomised, double-blind, placebo-controlled trial is actively enrolling patients and will study the efficacy, safety and tolerability of sildenafil or placebo in patients with advanced IPF and intermediate or high probability of Group 3 PH who are receiving a stable dose of pirfenidone...
May 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29721849/sunitinib-does-not-acutely-alter-left-ventricular-systolic-function-but-induces-diastolic-dysfunction
#16
Takeshi Wada, Kentaro Ando, Atsuhiko T Naito, Yuji Nakamura, Ai Goto, Koki Chiba, Nur Jaharat Lubna, Xin Cao, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Yuji Nakazato, Atsushi Sugiyama
PURPOSE: Cancer chemotherapies have improved the prognosis of cancer patients in recent years; however, their side effects on the cardiovascular systems have emerged as a major concern in the field of both cardiology and oncology. In particular, multi-targeted tyrosine kinase inhibitors are known to induce various types of cardiovascular adverse events including hypertension, QT-interval prolongation and heart failure, but their underlying mechanisms remain elusive. To explore how to better predict such drug-induced cardiovascular adverse events, we assessed the electropharmacological effects of sunitinib using the halothane-anesthetized dogs (n = 5), while plasma concentrations of cardiac enzymes including aspartate aminotransferase, lactate dehydrogenase, creatinine kinase and cardiac troponin I  were measured...
May 2, 2018: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/29720508/the-role-of-cardiopulmonary-exercise-tests-in-pulmonary-arterial-hypertension
#17
REVIEW
Stefania Farina, Michele Correale, Noemi Bruno, Stefania Paolillo, Elisabetta Salvioni, Roberto Badagliacca, Piergiuseppe Agostoni
Despite recent advances in the therapeutic management of patients affected by pulmonary arterial hypertension (PAH), survival remains poor. Prompt identification of the disease, especially in subjects at increased risk of developing PAH, and prognostic stratification of patients are a necessary target of clinical practice but remain challenging. Cardiopulmonary exercise test (CPET) parameters, particularly peak oxygen uptake, end-tidal carbon dioxide tension and the minute ventilation/carbon dioxide production relationship, emerged as new prognostic tools for PAH patients...
June 30, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29716823/apical-hypertrophic-cardiomyopathy-a-concerning-electrocardiogram-in-the-emergency-department
#18
Patrick J Rogers, Ann-Jeannette Geib, Darren Cuthbert, Grant Wei
BACKGROUND: Apical hypertrophic cardiomyopathy is a rare, complex phenotypic variant of the classically taught hypertrophic cardiomyopathy. It is highly variable in its pathophysiology as well as its clinical course, spanning the spectrum from a healthy asymptomatic lifestyle to sudden cardiac death and severe diastolic dysfunction. The hallmark electrocardiographic findings of unusually large T-wave inversions, in conjunction with the most common presenting symptom being chest pain, makes this disease entity concerning in the emergency department (ED) setting...
April 28, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29716705/evaluation-for-airway-obstruction-in-adult-patients-with-stable-ischemic-heart-disease
#19
M Mahendra, Sunil Kumar S, Nagaraj Desai, Jayaraj Bs, Mahesh Pa
BACKGROUND: Ischemic heart disease (IHD) and chronic airway disease (COPD and Asthma) are major epidemics accounting for significant mortality and morbidity. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. There is a need for airway evaluation in these patients to plan appropriate management. METHODS: Consecutive stable IHD patients attending the cardiology OPD in a tertiary care centre were interviewed for collecting basic demographic information, brief medical, occupational, personal history and risk factors for coronary artery disease and airway disease, modified medical research centre (MMRC) grade for dyspnea, quality of life-St...
March 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29712713/prevalence-of-masked-hypertension-in-untreated-and-treated-patients-with-office-blood-pressure-below-130-80-mm-hg
#20
Alejandro de la Sierra, José R Banegas, Ernest Vinyoles, Julián Segura, Manuel Gorostidi, Juan J de la Cruz, Luis M Ruilope
The recently released American College of Cardiology (ACC)/American Heart Association (AHA) hypertension guidelines1 proposed new values for defining hypertension: office blood pressure (BP) ≥130 systolic or ≥80 mm Hg diastolic. Furthermore, BP goals for hypertensive patients under pharmacological treatment have been recommended <130/80 mm Hg. New BP limits for office BP have been extended to define corresponding normal values for ambulatory BP monitoring (ABPM). Values of 125/75 mm Hg, 130/80 mm Hg, and 110/65 mm Hg have been proposed for 24-hour, daytime, and nighttime periods corresponding to the office cut-off of 130/80 mm Hg...
April 30, 2018: Circulation
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