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Physical activity, exercise

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https://www.readbyqxmd.com/read/29679658/effective-multicomponent-interventions-in-comparison-to-active-control-and-no-interventions-on-physical-capacity-cognitive-function-and-instrumental-activities-of-daily-living-in-elderly-people-with-and-without-mild-impaired-cognition-a-systematic-review-and
#1
REVIEW
Marina Bruderer-Hofstetter, Anne-Kathrin Rausch-Osthoff, André Meichtry, Thomas Münzer, Karin Niedermann
Multicomponent interventions (MCT) combine physical exercises and cognitive training and seem to be most effective in improving cognition in elderly people. However, literature is inconclusive if MCTs are superior to active comparison interventions, if delivery modes matter, and if people can transfer achieved effects to instrumental activities of daily living (IADL). This network meta-analysis aimed to a) identify MCTs that were effective on physical capacity and/or cognitive function and able to transfer these effects into IADL in elderly people with normal cognition (NC) and mild cognitive impairment (MCI); b) provide a rating on the best interventions per outcome; c) evaluate MCTs' mode of delivery...
April 18, 2018: Ageing Research Reviews
https://www.readbyqxmd.com/read/29679094/depletion-of-angiotensin-converting-enzyme-2-reduces-brain-serotonin-and-impairs-the-running-induced-neurogenic-response
#2
Friederike Klempin, Valentina Mosienko, Susann Matthes, Daniel C Villela, Mihail Todiras, Josef M Penninger, Michael Bader, Robson A S Santos, Natalia Alenina
Physical exercise induces cell proliferation in the adult hippocampus in rodents. Serotonin (5-HT) and angiotensin (Ang) II are important mediators of the pro-mitotic effect of physical activity. Here, we examine precursor cells in the adult brain of mice lacking angiotensin-converting enzyme (ACE) 2, and explore the effect of an acute running stimulus on neurogenesis. ACE2 metabolizes Ang II to Ang-(1-7) and is essential for the intestinal uptake of tryptophan (Trp), the 5-HT precursor. In ACE2-deficient mice, we observed a decrease in brain 5-HT levels and no increase in the number of BrdU-positive cells following exercise...
April 20, 2018: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29678773/microrna-132-is-associated-with-the-cognition-improvement-following-voluntary-exercise-in-samp8-mice
#3
Jingde Dong, Yi Liu, Zhen Zhan, Xiaoshan Wang
The senescence-accelerated SAMP8 mouse is characterized by progressive cognitive decline and is considered to be a specific model of Alzheimer's disease (AD). A growing body of evidence indicates that physical exercise suppresses age-related cognitive decline. In the current study, we investigated the influence of voluntary wheel running on cognitive function in SAMP8 mice. We found that voluntary physical exercise ameliorated cognition decline and suppressed hippocampal neurodegeneration in SAMP8 mice. MicroRNA-132 (miR-132) is a short non-coding RNA which is enriched in the brain and is implicated in the regulation of neuronal activity and cognitive function...
April 17, 2018: Brain Research Bulletin
https://www.readbyqxmd.com/read/29678148/knowledge-and-practice-of-patients-with-diabetes-mellitus-in-lebanon-a-cross-sectional-study
#4
Lamis R Karaoui, Mary E Deeb, Layal Nasser, Souheil Hallit
BACKGROUND: The objective of this study was to assess the knowledge and practice of Lebanese patients living with diabetes mellitus in regards to their diabetes self- management. METHODS: A cross-sectional study, conducted between January and June 2015, enrolled 207 urban adult patients with diabetes mellitus from community pharmacies while purchasing their diabetes medications. Their knowledge and self-management practices were assessed using a structured anonymous interview survey questionnaire...
April 20, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29677973/yorwalk-desiging-a-smartphone-exercise-application-for-people-with-intermittent-claudication
#5
Ahmed Shalan, Abubakar Abdulrahman, Ibrahim Habli, Garry Tew, Andrew Thompson
Peripheral Arterial Disease (PAD) is a chronic cardiovascular disease. It is highly prevalent in older adults. Mobile Health (mHealth) and Telehealth technologies are considered two central digital solutions for enabling patient-centred care. There is evidence that physical activity apps can improve health outcomes in adults. The aim of this project is to develop a prototype of smart phone app to target patients with PAD, which we named YORwalK, to promote exercise and track changes in walking ability in this population...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29676663/perceived-environmental-barriers-and-behavioral-factors-as-possible-mediators-between-acculturation-and-leisure-time-physical-activity-among-mexican-american-adults
#6
Carla L Dellaserra, Noe C Crespo, Michael Todd, Jennifer Huberty, Sonia Vega-López
BACKGROUND: The association between acculturation and physical activity (PA) among Mexican American (MA) adults is not understood. This study assessed potential mediating factors that may explain these associations among 75 healthy MA adults [age: 37.5 (9.3) y; 65.3% female]. METHODS: Secondary data analysis using hierarchical logistic regression examined whether perceived environmental barriers, social support, and intention to exercise potentially mediated relationships between acculturation level, and total and leisure-time moderate to vigorous PA (MVPA)...
April 20, 2018: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/29675670/principles-of-exercise-prescription-and-how-they-influence-exercise-induced-changes-of-transcription-factors-and-other-regulators-of-mitochondrial-biogenesis
#7
REVIEW
Cesare Granata, Nicholas A Jamnick, David J Bishop
Physical inactivity represents the fourth leading risk factor for mortality, and it has been linked with a series of chronic disorders, the treatment of which absorbs ~ 85% of healthcare costs in developed countries. Conversely, physical activity promotes many health benefits; endurance exercise in particular represents a powerful stimulus to induce mitochondrial biogenesis, and it is routinely used to prevent and treat chronic metabolic disorders linked with sub-optimal mitochondrial characteristics. Given the importance of maintaining a healthy mitochondrial pool, it is vital to better characterize how manipulating the endurance exercise dose affects cellular mechanisms of exercise-induced mitochondrial biogenesis...
April 19, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29675546/telehealth-applied-to-physical-activity-during-cancer-treatment-a-feasibility-acceptability-and-randomized-pilot-study
#8
Charlène Villaron, François Cury, François Eisinger, Maria-A Cappiello, Tanguy Marqueste
PURPOSE: Previous studies have underlined the benefits of exercise during cancer therapy. However, patients are insufficiently active during treatment. Telehealth is used to encourage people to be active, reducing difficulties and offsetting the lack of infrastructure often reported. We aimed to identify the effects of recommendations and telehealth on the level of physical activity, fatigue, and quality of life. METHODS: Sixty patients suffering from various cancers under treatment were randomized into two groups...
April 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29674667/a-mixed-periodic-paralysis-myotonia-mutant-p1158s-imparts-ph-sensitivity-in-skeletal-muscle-voltage-gated-sodium-channels
#9
Mohammad-Reza Ghovanloo, Mena Abdelsayed, Colin H Peters, Peter C Ruben
Skeletal muscle channelopathies, many of which are inherited as autosomal dominant mutations, include myotonia and periodic paralysis. Myotonia is defined by a delayed relaxation after muscular contraction, whereas periodic paralysis is defined by episodic attacks of weakness. One sub-type of periodic paralysis, known as hypokalemic periodic paralysis (hypoPP), is associated with low potassium levels. Interestingly, the P1158S missense mutant, located in the third domain S4-S5 linker of the "skeletal muscle", Nav1...
April 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29674240/the-impact-of-antipsychotics-as-a-risk-factor-for-thromboembolism
#10
REVIEW
Ewa A Ogłodek, Marek J Just, Anna D Grzesińska, Aleksander Araszkiewicz, Adam R Szromek
Patients with schizophrenia are predisposed toward developing cardiovascular disease. Although neuroleptics affect the cardiovascular system, it is also important to consider the consequences of the disease itself such as lower physical activity due to living on disability pension, inadequate nutrition, and/or nicotine addiction, being more common among patients with schizophrenia versus the general population. All these factors combined lead to an increased risk of death caused by cardiovascular conditions in schizophrenic patients...
December 15, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29673350/is-daily-physical-activity-affected-by-dynamic-hyperinflation-in-adults-with-cystic-fibrosis
#11
Daniela Savi, Marcello Di Paolo, Nicholas J Simmonds, Chiara Pascucci, Serena Quattrucci, Paolo Palange
BACKGROUND: The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis (CF). METHODS: Thirty-four clinically stable CF were studied. All patients undertook incremental cardiopulmonary exercise testing (CPET). CPET-related measurements included: oxygen uptake (V'O2 ), carbon dioxide production (V'CO2 ), ventilatory profile, work rate (W), inspiratory capacity (IC), end-expiratory lung volume (EELV)...
April 19, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29672438/alterations-of-inflammatory-and-matrix-production-indices-in-celiac-disease-with-low-bone-mass-on-long-term-gluten-free-diet
#12
Michele Di Stefano, Manuela Bergonzi, Irene Benedetti, Mara De Amici, Cristina Torre, Natascia Brondino, Emanuela Miceli, Elisabetta Pagani, Gian L Marseglia, Gino R Corazza, Antonio Di Sabatino
BACKGROUND: A clinically meaningful impairment of bone mass secondary to malabsorption is frequent in untreated celiac disease. In adult patients, a rigorous gluten-free diet (GFD) significantly improves, but does not always normalize, bone mineral density (BMD). The reason for this marginal response is unclear. Accordingly, we evaluated the role of both local and systemic factors for bone loss in celiac patients on long-term GFD. STUDY: In a prospective cohort, 22 patients with low lumbar and/or femoral BMD and 22 with normal BMD underwent bone and mineral metabolism evaluation: we tested calcium, phosphate, parathyroid hormone, and vitamin D; telopeptide of type I collagen, a bone resorption index; propeptide of type I procollagen, a bone neoformation index; receptor antagonist of NF-kB ligand, an osteoclast-stimulating factor; osteoprotegerin (OPG), a decoy receptor for RANKL...
April 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29671055/a-new-perspective-of-the-hippocampus-in-the-origin-of-exercise-brain-interactions
#13
REVIEW
Catarina Rendeiro, Justin S Rhodes
Exercising regularly is a highly effective strategy for maintaining cognitive health throughout the lifespan. Over the last 20 years, many molecular, physiological and structural changes have been documented in response to aerobic exercise training in humans and animals, particularly in the hippocampus. However, how exercise produces such neurological changes remains elusive. A recent line of investigation has suggested that muscle-derived circulating factors cross into the brain and may be the key agents driving enhancement in synaptic plasticity and hippocampal neurogenesis from aerobic exercise...
April 18, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29670751/comparing-physical-activity-in-individuals-with-overweight-obesity-with-and-without-binge-eating-disorder
#14
J A Barber, V Ivezaj, R D Barnes
Objective: Differential participation in physical activity (PA) may partially explain the health discrepancies between individuals with or without binge-eating disorder (BED). Yet, little is known about the PA habits of individuals with overweight/obesity and how those patterns may differ based on BED status. PA patterns and exercise self-efficacy were examined in individuals with overweight/obesity, with and without BED. Design: Ninety-seven participants with overweight/obesity self-reported their PA via the Godin Leisure-Time Questionnaire and the Paffenbarger PA Questionnaire...
April 2018: Obesity Science & Practice
https://www.readbyqxmd.com/read/29670343/effect-of-6-month-community-based-exercise-interventions-on-gait-and-functional-fitness-of-an-older-population-a-quasi-experimental-study
#15
Fátima Ramalho, Rita Santos-Rocha, Marco Branco, Vera Moniz-Pereira, Helô-Isa André, António P Veloso, Filomena Carnide
Background: Gait ability in older adults has been associated with independent living, increased survival rates, fall prevention, and quality of life. There are inconsistent findings regarding the effects of exercise interventions in the maintenance of gait parameters. Objectives: The aim of the study was to analyze the effects of a community-based periodized exercise intervention on the improvement of gait parameters and functional fitness in an older adult group compared with a non-periodized program...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29669711/an-exercise-intervention-to-unravel-the-mechanisms-underlying-insulin-resistance-in-a-cohort-of-black-south-african-women-protocol-for-a-randomized-controlled-trial-and-baseline-characteristics-of-participants
#16
Julia H Goedecke, Amy E Mendham, Louise Clamp, Pamela A Nono Nankam, Melony C Fortuin-de Smidt, Lindokuhle Phiri, Lisa K Micklesfield, Dheshnie Keswell, Nicholas J Woudberg, Sandrine Lecour, Ali Alhamud, Mamadou Kaba, Faith M Lutomia, Paul J van Jaarsveld, Anniza de Villiers, Steven E Kahn, Elin Chorell, Jon Hauksson, Tommy Olsson
BACKGROUND: The pathogenesis of type 2 diabetes (T2D) in black African women is complex and differs from that in their white counterparts. However, earlier studies have been cross-sectional and provide little insight into the causal pathways. Exercise training is consistently used as a model to examine the mechanisms underlying insulin resistance and risk for T2D. OBJECTIVE: The objective of the study was to examine the mechanisms underlying the changes in insulin sensitivity and secretion in response to a 12-week exercise intervention in obese black South African (SA) women...
April 18, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29669494/an-epidemiological-investigation-of-an-idiopathic-myopathy-in-hunting-dogs-in-new-zealand
#17
H Hunt, N J Cave, B D Gartrell, N Cogger, J Petersen, W D Roe
AIM: To conduct an epidemiological investigation of an idiopathic myopathy, known as "Go Slow" (GSM), which was initially recognised in dogs used for pig hunting. A secondary aim was to describe the hunting activities, diet and health of dogs used for pig hunting in New Zealand. METHODS: A retrospective cohort study was conducted between June 2014-June 2017. Cases of GSM in dogs were diagnosed by veterinarians using a combination of clinical history, physical examination findings, serum biochemistry and/or skeletal muscle histology...
April 18, 2018: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/29669488/physical-activity-and-exercise-therapy-benefits-more-than-just-symptoms-and-impairments-in-people-with-hip-and-knee-osteoarthritis
#18
Søren T Skou, Bente Klarlund Pedersen, J Haxby Abbott, Brooke Patterson, Christian Barton
Synopsis Hip and knee osteoarthritis (OA) are among the leading causes of global disability, highlighting the need for early, targeted, and effective treatments. The benefits on symptoms and impairments of exercise therapy in people with hip and knee OA are substantial and supported by high-quality evidence, underlining that it should be part of first line treatment offered to all people with hip and knee OA in clinical practice. Furthermore, unlike other treatments for OA such as analgesia and surgery, exercise therapy is not associated with risk of serious harm...
April 18, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29669470/web-based-rehabilitation-interventions-for-people-with-rheumatoid-arthritis-a-systematic-review
#19
Cynthia Srikesavan, Catherine Bryer, Usama Ali, Esther Williamson
Background Rehabilitation approaches for people with rheumatoid arthritis include joint protection, exercises and self-management strategies. Health interventions delivered via the web have the potential to improve access to health services overcoming time constraints, physical limitations, and socioeconomic and geographic barriers. The objective of this review is to determine the effects of web-based rehabilitation interventions in adults with rheumatoid arthritis. Methods Randomised controlled trials that compared web-based rehabilitation interventions with usual care, waiting list, no treatment or another web-based intervention in adults with rheumatoid arthritis were included...
January 1, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29668726/the-effects-of-mothers-musical-background-on-sedentary-behavior-physical-activity-and-exercise-adherence-in-their-5-6-years-old-children-using-movement-to-music-video-program
#20
Pipsa P A Tuominen, Jani Raitanen, Pauliina Husu, Urho M Kujala, Riitta M Luoto
OBJECTIVES: The purpose of this study was to examine whether mothers' musical background has an effect on their own and their children's sedentary behavior (SB) and physical activity (PA). The aim was also to assess children's and their mothers' exercise adherence when using movement-to-music video program. DESIGN: Sub-group analysis of an intervention group in a randomized controlled trial (ISRCTN33885819). METHOD: Seventy-one mother-child-pairs were divided into two categories based on mothers' musical background...
2018: PloS One
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