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https://www.readbyqxmd.com/read/29474996/considerations-for-exercise-prescription-in-patients-with-bone-metastases-a-comprehensive-narrative-review
#1
REVIEW
Gráinne Sheill, Emer M Guinan, Nicola Peat, Juliette Hussey
Metastatic disease is a frequent complication of advanced cancer, with bone representing one of the most common sites of metastatic occurrence. Patients with bone metastases receive long-term systemic treatments which have a significant attritional impact on muscle strength, fatigue and physical functioning. Physical rehabilitation involving exercise and physical activity prescription has a considerable role in counteracting these changes however exercise is often perceived as a contraindication in the presence of bone metastases due to concerns about aggravating skeletal related events...
February 20, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29474685/process-evaluation-of-the-healthesteps%C3%A2-lifestyle-prescription-program
#2
Wendy Blunt, Dawn P Gill, Brendan Riggin, Judith Belle Brown, Robert J Petrella
Physical inactivity, sedentary behavior, and poor diet are contributing to the rise in chronic disease rates throughout the world. HealtheSteps™ is a lifestyle prescription program focused on reducing risk factors for chronic disease through in-person coaching sessions, goal setting and tracking, and technology supports. A process evaluation was conducted alongside a pragmatic randomized controlled trial to: (a) explore the acceptability of HealtheSteps™ program from coach and participant perspectives; and (b) identify where the program can be improved...
February 21, 2018: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/29473995/chronic-inflammation-in-skeletal-muscle-impairs-satellite-cells-function-during-regeneration-can-physical-exercise-restore-the-satellite-cell-niche
#3
Luiz Augusto Perandini, Patricia Chimin, Diego da Silva Lutkemeyer, Niels Olsen Saraiva Câmara
Chronic inflammation impairs skeletal muscle regeneration. Although many cells are involved in chronic inflammation, macrophages seem to play an important role in impaired muscle regeneration since these cells are associated with skeletal muscle stem cell (namely, satellite cells) activation and fibro-adipogenic progenitor cell (FAP) survival. Specifically, an imbalance of M1 and M2 macrophages seems to lead to impaired satellite cell activation, and these are the main cells that function during skeletal muscle regeneration, after muscle damage...
February 23, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29473645/locomotor-activity-growth-hormones-and-systemic-robusticity-an-investigation-of-cranial-vault-thickness-in-mouse-lines-bred-for-high-endurance-running
#4
L E Copes, H Schutz, E M Dlugsoz, S Judex, T Garland
OBJECTIVES: To use a mouse model to investigate the relationships among the components of the systemic robusticity hypothesis (SRH): voluntary exercise on wheels, spontaneous physical activity (SPA) in cages, growth hormones, and skeletal robusticity, especially cranial vault thickness (CVT). MATERIALS AND METHODS: Fifty female mice from lines artificially selected for high running (HR) and 50 from nonselected control (C) lines were housed in cages with (Active) or without wheels (Sedentary)...
February 23, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29473170/determination-of-physical-health-status-and-healthy-lifestyle-behaviors-of-individuals-with-mental-illness
#5
Derya Kayar Erginer, Neslihan Partlak Günüşen
PURPOSE: The aim of this study is to determine the physical health status and healthy lifestyle behaviors of individuals with mental illness. DESIGN AND METHODS: A descriptive research design was used. The sample of the study consisted of 115 individuals with mental illness. The Health Lifestyle Behaviors Scale II was used to assess the healthy lifestyle behaviors of the participants. FINDINGS: Of the individuals, 49.6% were found to have metabolic syndrome...
February 23, 2018: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/29472870/high-intensity-interval-training-in-normobaric-hypoxia-leads-to-greater-body-fat-loss-in-overweight-obese-women-than-high-intensity-interval-training-in-normoxia
#6
Alba Camacho-Cardenosa, Marta Camacho-Cardenosa, Martin Burtscher, Ismael Martínez-Guardado, Rafael Timon, Javier Brazo-Sayavera, Guillermo Olcina
A moderate hypoxic stimulus is considered a promising therapeutic modality for several pathological states including obesity. There is scientific evidence suggesting that when hypoxia and physical activity are combined, they could provide benefits for the obese population. The aim of the present study was to investigate if exposure to hypoxia combined with two different protocols of high-intensity interval exercise in overweight/obese women was more effective compared with exercise in normoxia. Study participants included 82 overweight/obese women, who started a 12 week program of 36 sessions, and were randomly divided into four groups: (1) aerobic interval training in hypoxia (AitH; FiO2 = 17...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29471131/aerobic-and-strength-training-induce-changes-in-oxidative-stress-parameters-and-elicit-modifications-of-various-cellular-components-in-skeletal-muscle-of-aged-rats
#7
Thais Ceresér Vilela, Pauline Souza Effting, Giulia Dos Santos Pedroso, Hemelin Farias, Lara Paganini, Helen Sorato Rebelo, Renata Tiescoski Nesi, Vanessa Moraes de Andrade, Ricardo Aurino de Pinho
Skeletal muscle aging is associated with loss of mass, function, and strength-a condition known as sarcopenia. It has been reported that sarcopenia can be attenuated by physical exercise. Therefore, we investigated whether 2 different physical exercise protocols could modulate and induce changes in oxidative and inflammatory parameters, as well as in BDNF and DNA repair enzyme levels in skeletal muscle tissue of aged rats. Aging Wistar rats performed treadmill or strength training for 50 min 3 to 4 times a week for 8 weeks...
February 19, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29470447/empirical-examinations-of-effects-of-three-level-green-exercise-on-engagement-with-nature-and-physical-activity
#8
Ke-Tsung Han, Po-Ching Wang
Green exercise can be classified into three levels based on engagement with nature. Although this classification was proposed more than a decade ago, few studies have investigated it since. The present study examined the effects of green exercise levels on engagement with nature and physical activity (PA) through a field experiment. A questionnaire was distributed to 95 students from a technology university in Central Taiwan to measure their level of engagement with nature in people-environment transactions, while their PA was measured using three instruments...
February 22, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29468901/osteochondritis-dissecans-of-the-knee-conservative-treatment-strategies-a-systematic-review
#9
Luca Andriolo, Christian Candrian, Tiziana Papio, Alessia Cavicchioli, Francesco Perdisa, Giuseppe Filardo
Objective Osteochondritis dissecans (OCD) lesions are a relevant problem that affects the long-term prognosis of young patients. The purpose of this study was to analyze the evidence on potential and indications of nonsurgical treatment strategies for knee OCD. Design The search was conducted on 3 medical electronic databases according to PRISMA guidelines, including reports of any level of evidence dealing with the conservative management of knee OCD. Of 1688 identified records, 55 full-text articles were screened: 27 studies met the inclusion criteria, for a total of 908 knees, and were used for the analysis...
February 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29467606/integrating-brain-and-biomechanical-models-a-new-paradigm-for-understanding-neuro-muscular-control
#10
Sebastian S James, Chris Papapavlou, Alexander Blenkinsop, Alexander J Cope, Sean R Anderson, Konstantinos Moustakas, Kevin N Gurney
To date, realistic models of how the central nervous system governs behavior have been restricted in scope to the brain, brainstem or spinal column, as if these existed as disembodied organs. Further, the model is often exercised in relation to an in vivo physiological experiment with input comprising an impulse, a periodic signal or constant activation, and output as a pattern of neural activity in one or more neural populations. Any link to behavior is inferred only indirectly via these activity patterns...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29467135/physiological-responses-to-arm-versus-leg-activity-in-patients-with-chronic-obstructive-pulmonary-disease-a-systematic-review-protocol
#11
Erik Frykholm, Vanessa Pereira Lima, Tania Janaudis-Ferreira, Andre Nyberg
INTRODUCTION: Compared with healthy older adults, people with chronic obstructive pulmonary disease (COPD) have reduced capacity and increased symptoms during leg and arm activities. While the mechanisms underlying limitations and symptoms during leg activities have been investigated in detail, limitations and symptoms during arm activities are not well understood, and the potential differences between physiological responses of leg and arm activities have not been systematically synthesised...
February 21, 2018: BMJ Open
https://www.readbyqxmd.com/read/29466693/acute-extracellular-matrix-inflammatory-and-mapk-response-to-lengthening-contractions-in-elderly-human-skeletal-muscle
#12
Jacob R Sorensen, Caitlin Skousen, Alex Holland, Kyle Williams, Robert D Hyldahl
To uncover potential factors that may be involved in the impaired regenerative capacity of aged skeletal muscle, we comprehensively assessed the molecular stress response following muscle damage in old and young individuals. 10 young (22.7 ± 2.25 yrs) and 8 physically active old (70.9 ± 7.5 yrs) subjects completed a bout of 300 lengthening contractions (LC), and muscle biopsies were taken pre-exercise and at 3, 24, and 72 h post-LC. Both age groups performed the same amount of work during LC, with the old group displaying a resistance to LC-induced fatigue during the exercise...
February 18, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29466285/the-impact-of-brain-breaks-classroom-based-physical-activities-on-attitudes-toward-physical-activity-in-polish-school-children-in-third-to-fifth-grade
#13
Agata Glapa, Joanna Grzesiak, Ida Laudanska-Krzeminska, Ming-Kai Chin, Christopher R Edginton, Magdalena Mo Ching Mok, Michal Bronikowski
The purpose of this study was to examine the effectiveness of the Brain Breaks® Physical Activity Solutions in changing attitudes toward physical activity of school children in a community in Poland. In 2015, a sample of 326 pupils aged 9-11 years old from 19 classes at three selected primary schools were randomly assigned to control and experimental groups within the study. During the classes, children in the experimental group performed physical activities two times per day in three to five minutes using Brain Breaks® videos for four months, while the control group did not use the videos during the test period...
February 21, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29466246/modified-aging-of-elite-athletes-revealed-by-analysis-of-epigenetic-age-markers
#14
Magdalena Spólnicka, Ewelina Pośpiech, Jakub Grzegorz Adamczyk, Ana Freire-Aradas, Beata Pepłońska, Renata Zbieć-Piekarska, Żanetta Makowska, Anna Pięta, Maria Victoria Lareu, Christopher Phillips, Rafał Płoski, Cezary Żekanowski, Wojciech Branicki
Recent progress in epigenomics has led to the development of prediction systems that enable accurate age estimation from DNA methylation data. Our objective was to track responses to intense physical exercise of individual age-correlated DNA methylation markers and to infer their potential impact on the aging processes. The study showed accelerated DNA hypermethylation for two CpG sites in TRIM59 and KLF14 . Both markers predicted the investigated elite athletes to be several years older than controls and this effect was more substantial in subjects involved in power sports...
February 15, 2018: Aging
https://www.readbyqxmd.com/read/29465155/effects-of-physical-activity-on-sclerostin-concentrations
#15
Małgorzata Janik, Michał Stuss, Marta Michalska-Kasiczak, Anna Jegier, Ewa Sewerynek
Osteoporosis is a serious medical and socioeconomic problem of the 21st century. Mechanical load is a key regulator which controls bone formation and remodelling, with participation of osteocytes. Sclerostin is produced and released by mature osteocytes into bone surface, where it inhibits the conveyance of osteoblast proliferation and differentiation activating signals from mesenchymal cells, thus suppressing new bone formation. The goal of the study was an evaluation of the effects of a 12-week physical training programme on the levels of bone turnover markers [Sclerostin, Osteocalcin (OC), C-terminal telopeptide of type I collagen (β-CTX)] in blood serum of women with osteopenia...
February 21, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29464992/childhood-obesity-physical-activity-and-exercise-the-year-that-was-2017-normal-weight-obese-are-we-missing-a-population-in-need
#16
Dan Nemet
No abstract text is available yet for this article.
February 21, 2018: Pediatric Exercise Science
https://www.readbyqxmd.com/read/29463936/relationship-between-social-participation-physical-activity-and-psychological-distress-in-apparently-healthy-elderly-people-a-pilot-study
#17
Yutaka Owari, Nobuyuki Miyatake, Hiroaki Kataoka
Few studies examined the relationship between social participation, physical activity and psychological distress in elderly people. Here we examined these relationships in apparently healthy elderly people. After exclusion of subjects who dropped out or did not meet enrollment criteria, the data of 86 subjects (apparently healthy elderly embers at a college health club; 25 males, 61 females) from July 20 to September 10, 2016 were used. We evaluated each subject's psychological distress using the K6 questionnaire, social participation by a self-completed questionnaire, and physical activity level by a triaxial accelerometer (7 consecutive days)...
February 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29463708/environmental-enrichment-and-exercise-are-better-than-social-enrichment-to-reduce-memory-deficits-in-amyloid-beta-neurotoxicity
#18
Mariza G Prado Lima, Helen L Schimidt, Alexandre Garcia, Letícia R Daré, Felipe P Carpes, Ivan Izquierdo, Pâmela B Mello-Carpes
Recently, nongenetic animal models to study the onset and development of Alzheimer's disease (AD) have appeared, such as the intrahippocampal infusion of peptides present in Alzheimer amyloid plaques [i.e., amyloid-β (Aβ)]. Nonpharmacological approaches to AD treatment also have been advanced recently, which involve combinations of behavioral interventions whose specific effects are often difficult to determine. Here we isolate the neuroprotective effects of three of these interventions-environmental enrichment (EE), anaerobic physical exercise (AnPE), and social enrichment (SE)-on Aβ-induced oxidative stress and on impairments in learning and memory induced by Aβ...
February 20, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29462924/achieving-optimal-post-exercise-muscle-protein-remodeling-in-physically-active-adults-through-whole-food-consumption
#19
REVIEW
Stephan van Vliet, Joseph W Beals, Isabel G Martinez, Sarah K Skinner, Nicholas A Burd
Dietary protein ingestion is critical to maintaining the quality and quantity of skeletal muscle mass throughout adult life. The performance of acute exercise enhances muscle protein remodeling by stimulating protein synthesis rates for several hours after each bout, which can be optimized by consuming protein during the post-exercise recovery period. To date, the majority of the evidence regarding protein intake to optimize post-exercise muscle protein synthesis rates is limited to isolated protein sources...
February 16, 2018: Nutrients
https://www.readbyqxmd.com/read/29462186/lack-of-infrastructure-social-and-cultural-factors-limit-physical-activity-among-patients-with-type-2-diabetes-in-rural-sri-lanka-a-qualitative-study
#20
Arjuna Medagama, Manoj Galgomuwa
INTRODUCTION: South Asians have high prevalence of diabetes, increased cardiovascular risk and low levels of physical activity (PA). Reasons for low levels of PA have not previously been explored among Asians living within their endogenous environment. This qualitative study was performed to explore the contextual reasons that limited PA among type 2 diabetic patients living in a rural community. METHODS: Purposeful sampling recruited 40 participants with long standing type 2 diabetes for this qualitative study...
2018: PloS One
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