Hannes Becker, Antonio Vogelsberg, Daniel Feucht, Arne Estler, Deniz Tafrali, Jens Schittenhelm, Jakob Milla, Sylvia Kurz, Falko Fend, Marcos Tatagiba, Martin U Schuhmann, Helene Hurth
BACKGROUND: Neoplastic lesions affecting peripheral nerves are rare in the general population and, most often, are benign peripheral nerve sheath tumors. However, a minority of lesions represent high-grade malignancies associated with a poor prognosis, such as malignant peripheral nerve sheath tumors (MPNSTs). Very rarely, these tumors represent peripheral non-nerve sheath tumors (PNNSTs), such as hematological neoplasms that impair nerve function. These can be hard to distinguish from MPNSTs and other lesions arising from the nerve itself...
2024: Frontiers in Oncology