Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Asdis Sveinsdottir, Ingibjörg J Gudmundsdottir, Johann P Hreinsson, Karl Andersen, Einar S Björnsson
BACKGROUND: Patients undergoing percutaneous coronary intervention (PCI) require dual antiplatelet therapy and some require additional anticoagulation. We aimed to investigate the incidence of acute gastrointestinal bleeding (AGIB) among PCI patients receiving antiplatelet and anticoagulant therapy. METHODS: A population-based study that included all patients undergoing PCI during 2008-2016 in Iceland. Data from the Icelandic Medicines Registry were obtained on all outpatient prescriptions 1 year after first PCI...
April 1, 2021: Scandinavian Journal of Gastroenterology
#22
JOURNAL ARTICLE
Zhihui Duan, Qiong Duan, Kun Liu, Xiaochong Zhang, Shengyun Zhou, On Behalf Of Xingtai Society Of Digestive Endoscopy
BACKGROUND AND AIMS: The coronavirus disease 2019 (COVID-19) has severely impacted the daily practice of gastrointestinal endoscopy worldwide. Most endoscopy centers in China were shut down in late January 2020. We investigated the impact of the shutdown on acute upper gastrointestinal bleeding (AUGIB) events in Xingtai City, Hebei Province, China. METHODS: A web-based survey collected information on gastroscopy workload and AUGIB events. The study period was from 4 weeks before to 4 weeks after lockdown initiation in Xingtai City...
2021: Gastroenterology Research and Practice
#23
JOURNAL ARTICLE
Johann P Hreinsson, Armann Jonsson, Einar S Bjornsson
OBJECTIVE: Data on long-term rebleeding risk and mortality in acute upper gastrointestinal bleeding (AUGIB) patients are scarce and comparison to controls are lacking. Aimsof the study were to assess long-term prognosis of AUGIB patients and compare to controls. METHODS: A population-based retrospective case-control study conducted at the National University Hospital of Iceland and included all patients who underwent endoscopy in 2010-2011. AUGIB was defined as haematemesis or coffee ground vomiting leading to hospitalization or occurring in a hospitalized patient...
January 2021: Scandinavian Journal of Gastroenterology
#24
JOURNAL ARTICLE
Keith Siau, A John Morris, Aravinth Murugananthan, Brian McKaig, Paul Dunckley
Introduction: Gastroenterologists are typically expected to be competent in endoscopic haemostasis for acute upper gastrointestinal bleeding (AUGIB), with the Certificate of Completion of Training (CCT) often heralding the onset of participation in on-call AUGIB rotas. We analysed the volume of haemostasis experience recorded by gastroenterology CCT holders on the Joint Advisory Group on Gastrointestinal Endoscopy Training System (JETS) e-portfolio, the UK electronic portfolio for endoscopy, and assessed for variations in exposure to haemostasis...
October 2020: Frontline Gastroenterology
#25
JOURNAL ARTICLE
Jonathan Segal, Keith Siau, Cynthia Kanagasundaram, Alan Askari, Paul Dunckley, Allan John Morris
INTRODUCTION: Competence in endoscopic haemostasis for acute upper gastrointestinal bleeding (AUGIB) is typically expected upon completion of gastroenterology training. However, training in haemostasis is currently variable without a structured training pathway. We conducted a national gastroenterology trainee survey on haemostasis exposure and on attitudes and barriers to training. METHODS: A 24-item electronic survey was distributed to UK gastroenterology trainees covering the following domains: demographics, training setup, attitudes and barriers, confidence in managing AUGIB independently and exposure to individual haemostatic modalities (supervised and independent)...
October 2020: Frontline Gastroenterology
#26
JOURNAL ARTICLE
M Zaeem Cader, Massimiliano Di Pietro
No abstract text is available yet for this article.
November 2020: Gastroenterology
#27
JOURNAL ARTICLE
Riccardo Marmo, Marco Soncini, Roberto de Franchis
BACKGROUND: Non-variceal acute UGI bleeding (NV-AUGIB) is a frequent indication for transfusion, but the best hemoglobin threshold and target values for transfusion in relation to the patients' performance status are unknown. OBJECTIVE: To identify threshold and target hemoglobin levels for transfusion favoring survival of patients with NV-AUGIB stratified by ASA score. DESIGN: Prospective cohort study. SETTING: 50 hospitals of the Italian National Health Service...
August 9, 2020: Digestive and Liver Disease
#28
JOURNAL ARTICLE
Yang An, Zhaohui Bai, Xiangbo Xu, Xiaozhong Guo, Fernando Gomes Romeiro, Cyriac Abby Philips, Yingying Li, Yanyan Wu, Xingshun Qi
BACKGROUND AND AIMS: Acute upper gastrointestinal bleeding (AUGIB) is one of the most life-threatening emergency conditions. Hemostatic drugs are often prescribed to control AUGIB in clinical practice but have not been recommended by major guidelines and consensus. The aim of this study was to investigate the therapeutic effect of hemostatic drugs on AUGIB in cirrhosis. METHODS: All cirrhotic patients with AUGIB who were admitted to our hospital from January 2010 to June 2014 were retrospectively included...
2020: BioMed Research International
#29
JOURNAL ARTICLE
Keith Siau, Sarah Hearnshaw, Adrian J Stanley, Lise Estcourt, Ashraf Rasheed, Andrew Walden, Mo Thoufeeq, Mhairi Donnelly, Russell Drummond, Andrew M Veitch, Sauid Ishaq, Allan John Morris
Medical care bundles improve standards of care and patient outcomes. Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency which has been consistently associated with suboptimal care. We aimed to develop a multisociety care bundle centred on the early management of AUGIB. Commissioned by the British Society of Gastroenterology (BSG), a UK multisociety task force was assembled to produce an evidence-based and consensus-based care bundle detailing key interventions to be performed within 24 hours of presentation with AUGIB...
2020: Frontline Gastroenterology
#30
JOURNAL ARTICLE
Jingqiao Zhang, Jie Liu, Yunhai Wu, Fernando Gomes Romeiro, Giovanni Battista Levi Sandri, Xinmiao Zhou, Miaomiao Li, Xingshun Qi
BACKGROUND: Renal dysfunction is a serious morbidity in cirrhotic patients with acute upper gastrointestinal bleeding (AUGIB). Terlipressin is the first-line treatment choice for acute variceal bleeding and hepatorenal syndrome (HRS). This study aimed to assess the effect of terlipressin on renal function in patients with liver cirrhosis and AUGIB. METHODS: We retrospectively reviewed 40 cirrhotic patients with AUGIB treated with terlipressin by an attending physician between January 2016 and June 2018...
March 2020: Annals of Translational Medicine
#31
JOURNAL ARTICLE
Fady G Haddad, Talal El Imad, Najib Nassani, Raymond Kwok, Hassan Al Moussawi, Abhishek Polavarapu, Moiz Ahmed, Youssef El Douaihy, Liliane Deeb
BACKGROUND: Acute upper gastrointestinal bleeding (AUGIB) is a frequently encountered condition in the Gastroenterology field with a mortality rate of 10-14%. Despite recent newer innovations and advancements in endoscopic techniques and available medications, the mortality rate associated with AUGIB remained persistently elevated. AIM: To explore mortality, characteristics and outcome differences between hospitalized patients who develop AUGIB while in-hospital, and patients who initially present with AUGIB...
December 16, 2019: World Journal of Gastrointestinal Endoscopy
#32
JOURNAL ARTICLE
Jennifer Tham, Adrian Stanley
Introduction : Acute upper-gastrointestinal bleeding (AUGIB) is a common medical emergency, with an incidence of 103-172 per 100,000 in the United Kingdom (UK) and mortality of 2% to 10%. Early and accurate prediction of the severity of an AUGIB episode may help guide management, including in or outpatient management, level of care required, and timing of endoscopy. This article aims to address the clinical utility of the various pre-endoscopic risk assessment tools used in AUGIB. Areas covered : The authors undertook a literature review of the current evidence on the pre-endoscopic risk assessment scores...
December 2019: Expert Review of Gastroenterology & Hepatology
#33
JOURNAL ARTICLE
Yingying Li, Hongyu Li, Qiang Zhu, Emmanuel Tsochatzis, Ran Wang, Xiaozhong Guo, Xingshun Qi
OBJECTIVES: Patients with acute upper gastrointestinal bleeding (AUGIB) often manifest as hematemesis and melena. Theoretically, hematemesis will carry worse outcomes of AUGIB. However, there is little real-world evidence. We aimed to compare the outcomes of hematemesis versus no hematemesis as a clinical manifestation of AUGIB at admission in cirrhotic patients. METHODS: All cirrhotic patients with AUGIB who were consecutively admitted to our hospital from January 2010 to June 2014 were considered in this retrospective study...
September 11, 2019: European Journal of Gastroenterology & Hepatology
#34
JOURNAL ARTICLE
Xingshun Qi, Yiling Li, Ran Wang, Lianjie Lin, Jing Li, Lijun Wang, Shuang Zheng, Yonghong Sun, Lixin Zhao, Xiaolin Fu, Mengchun Wang, Xinping Qiu, Han Deng, Chen Hong, Qianqian Li, Hongyu Li, Xiaozhong Guo
BACKGROUND AND AIMS: Endoscopy is necessary for assessment of esophageal varices (EVs) in cirrhotic patients, but its use is limited because of the poor compliance of patients and shortage of public health resources at primary hospitals or rural areas, especially in less well developed countries. A multicenter cross-sectional study aimed to establish a novel non-invasive score for prediction of EVs in cirrhotic patients who had never undergone endoscopy. METHODS: Patients with liver cirrhosis regardless of acute upper gastrointestinal bleeding (AUGIB) who underwent the first-time upper gastrointestinal endoscopy at 11 hospitals in Liaoning Province, China were considered...
May 15, 2019: Advances in Therapy
#35
MULTICENTER STUDY
Keith Siau, James Hodson, Richard Ingram, Andrew Baxter, Monika M Widlak, Caroline Sharratt, Graham M Baker, Tom Troth, Ben Hicken, Faraz Tahir, Malik Magrabi, Nouman Yousaf, Claire Grant, Dennis Poon, Hesham Khalil, Hui Lin Lee, Jonathan R White, Huey Tan, Syazeddy Samani, Patricia Hooper, Saeed Ahmed, Muhammad Amin, Sara Mahgoub, Khayal Asghar, Farique Leet, Matthew J Harborne, Beata Polewiczowska, Sheeba Khan, Muhammad R Anjum, Michael McFarlane, Ella Mozdiak, Lauren D O'Flynn, Ilona C Blee, Rachel M Molyneux, Ashok Kurian, Syed N Abbas, Abdullah Abbasi, Aadil Karim, Asif Yasin, Fawad Khattak, Josephine White, Ruhina Ahmed, James A Morgan, Lance Alleyne, Mohamed A Alam, Naaventhan Palaniyappan, Victoria J Rodger, Paramvir Sawhney, Nasar Aslam, Theodore Okeke, Adam Lawson, Danny Cheung, Jeremy P Reid, Ashish Awasthi, Mark R Anderson, Joe R Timothy, Sanjeev Pattni, Saqib Ahmad, Gillian Townson, Jeremy Shearman, Vanja Giljaca, Matthew J Brookes, Ben R Disney, Neil Guha, Titus Thomas, Anthony Norman, Peter Wurm, Ashit Shah, Neil C Fisher, Sauid Ishaq, Giles Major
BACKGROUND: Endoscopy within 24 h of admission (early endoscopy) is a quality standard in acute upper gastrointestinal bleeding (AUGIB). We aimed to audit time to endoscopy outcomes and identify factors affecting delayed endoscopy (>24 h of admission). METHODS: This prospective multicentre audit enrolled patients admitted with AUGIB who underwent inpatient endoscopy between November and December 2017. Analyses were performed to identify factors associated with delayed endoscopy, and to compare patient outcomes, including length of stay and mortality rates, between early and delayed endoscopy groups...
March 2019: United European Gastroenterology Journal
#36
REVIEW
Durayd Alzoubaidi, Laurence B Lovat, Rehan Haidry
Acute upper gastrointestinal bleeding (AUGIB) is one of the most common medical emergencies in the UK. Despite advancement in technology the management of AUGIB remains a challenge. The clinical community recognise the need for improvement in the treatment of these patients. AUGIB has a significant impact on resources. Endoscopic therapy is the gold standard treatment. The mortality in AUGIB is rarely related to the presenting bleed but significantly associated with concurrent comorbidities. The cost of blood transfusion in the management of patients with AUGIB is significant and misuse of blood products has been documented nationally...
January 2019: Frontline Gastroenterology
#37
JOURNAL ARTICLE
Thomas Banister, Josesph Spiking, Lakshmana Ayaru
OBJECTIVE: To use an extended Glasgow-Blatchford Score (GBS) cut-off of ≤1 to aid discharge of patients presenting with acute upper gastrointestinal bleeding (AUGIB) from emergency departments. BACKGROUND: The GBS accurately predicts the need for intervention and death in AUGIB, and a cut-off of 0 is recommended to identify patients for discharge without endoscopy. However, this cut-off is limited by identifying a low percentage of low-risk patients. Extension of the cut-off to ≤1 or ≤2 has been proposed to increase this proportion, but there is controversy as to the optimal cut-off and little data on performance in routine clinical practice...
2018: BMJ Open Gastroenterology
#38
JOURNAL ARTICLE
Mike Thomson, Arun Urs, Priya Narula, Prithviraj Rao, Dalia Belsha
AIMS AND BACKGROUND: Advanced endohaemostatic technique performance and experience is extremely variable in distribution amongst paediatric endoscopists. Haemostatic spray (Hemospray), a novel endohaemostatic topically applied powder has the advantage of extreme ease of use and; hence may lower the threshold of competency required by the endoscopist thereby potentially reducing mortality. The aim of the study is to prospectively evaluate the efficacy and the safety of haemostatic spray in paediatric patients with acute upper gastrointestinal bleeding (AUGIB)...
September 2018: Journal of Pediatric Gastroenterology and Nutrition
#39
JOURNAL ARTICLE
K Siau, W Chapman, N Sharma, D Tripathi, T Iqbal, N Bhala
Acute upper gastrointestinal bleed (AUGIB) is one of the most common medical emergencies in the UK, with roughly one presentation every 6 min. Despite advances in therapeutics and endoscopy provision, mortality following AUGIB over the last two decades has remained high, with over 9,000 deaths annually in the UK; consequently, several national bodies have published UK-relevant guidelines. Despite this, the 2015 UK National Confidential Enquiry into Patient Outcome and Death in AUGIB highlighted variations in practice, raised concerns regarding suboptimal patient care and released a series of recommendations...
September 2017: Journal of the Royal College of Physicians of Edinburgh
#40
JOURNAL ARTICLE
Kanthi Rekha Badipatla, Preeti Jadhav, Sushma Vaddigiri, Bharat Bajantri, Amandeep Singh, Chaitanya Chandrala, Vijay S Are, Suresh Kumar Nayudu
Background: Diabetic ketoacidosis (DKA) is a common acute complication of diabetes mellitus requiring aggressive medical management. We attempted to study the incidence and various clinical and laboratory variables associated with acute gastrointestinal bleeding (AGIB) and acute upper AGIB (AUGIB) in patients with DKA. Methods: We conducted a retrospective chart review of all the patients admitted to our hospital with DKA between January 2010 and December 2015. We collected demographic, clinical, laboratory, endoscopy and hospitalization details using an electronic medical-record database...
November 2017: Gastroenterology Report
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
