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Ureter obstruction

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https://www.readbyqxmd.com/read/28537409/-ureterointestinal-anastomosis-in-urinary-diversion-current-opinion
#1
J Doležel
Uretero-intestinal anastomosis (UIA) is one of the most critical points for the occurrence of severe complications of intestinal urinary diversion. Perfection of the current techniques and development of new UIA methods are motivated by the effort to reduce both early and late post-surgical complications. The necessity of using antireflux UIA, especially with an orthotopic neobladder, is controversial: according to some authors, antireflux UIA of any type generally increases, in comparison with reflux UIA, the risk of obstruction that endangers renal function more than the urine reflux itself...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28536083/preoperatively-dilated-ureters-are-a-specific-risk-factor-for-the-development-of-ureteroenteric-strictures-after-open-radical-cystectomy-and-ileal-neobladder
#2
Richard E Hautmann, Robert de Petriconi, Andreas Kahlmeyer, Melanie Enders, Bjoern Volkmer
PURPOSE: To evaluate preoperative ureteral obstruction as risk factor for the development of benign UEAS in patients undergoing open RC and INB diversion. MATERIAL AND METHODS: 953 patients with bilateral ileoureterostomy, performed between 01/86 and 03/09, form the study population with a non-refluxing (Le Duc) technique in 357 and a refluxing (Wallace type) technique in 596 consecutive patients. We defined UEAS as need for specific therapy (e.g. stenting, dilatation, reimplantation) or proven loss of renal function...
May 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28508426/the-role-of-transvaginal-ultrasound-in-the-evaluation-of-ureteral-involvement-in-deep-endometriosis
#3
P Carfagna, C De Cicco Nardone, A De Cicco Nardone, A C Testa, G Scambia, R Marana, F De Cicco Nardone
OBJECTIVE: To assess whether routine visualization of the pelvic ureter during transvaginal ultrasonography should be performed in all patients with deep endometriosis candidate to surgery, in order to identify a potential silent ureteral involvement by the disease. METHODS: This was a prospective study of 200 consecutive patients undergoing surgery for deep endometriosis, evaluated between January 2012 and December 2014 at a tertiary endometriosis center at the Department of Obstetrics and Gynecology, Fondazione Policlinico Universitario A...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28507324/a-novel-indole-compound-ma-35-attenuates-renal-fibrosis-by-inhibiting-both-tnf-%C3%AE-and-tgf-%C3%AE-1-pathways
#4
Hisato Shima, Kensuke Sasaki, Takehiro Suzuki, Chikahisa Mukawa, Ten Obara, Yuki Oba, Akihiro Matsuo, Takayasu Kobayashi, Eikan Mishima, Shun Watanabe, Yasutoshi Akiyama, Koichi Kikuchi, Tetsuro Matsuhashi, Yoshitsugu Oikawa, Fumika Nanto, Yukako Akiyama, Hsin-Jung Ho, Chitose Suzuki, Daisuke Saigusa, Atsushi Masamune, Yoshihisa Tomioka, Takao Masaki, Sadayoshi Ito, Ken-Ichiro Hayashi, Takaaki Abe
Renal fibrosis is closely related to chronic inflammation and is under the control of epigenetic regulations. Because the signaling of transforming growth factor-β1 (TGF-β1) and tumor necrosis factor-α (TNF-α) play key roles in progression of renal fibrosis, dual blockade of TGF-β1 and TNF-α is desired as its therapeutic approach. Here we screened small molecules showing anti-TNF-α activity in the compound library of indole derivatives. 11 out of 41 indole derivatives inhibited the TNF-α effect. Among them, Mitochonic Acid 35 (MA-35), 5-(3, 5-dimethoxybenzyloxy)-3-indoleacetic acid, showed the potent effect...
May 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28494578/early-and-late-ureteral-complications-after-renal-transplant-a-case-series-in-838-patients
#5
Francesca Manassero, Fabio Vistoli, Andrea Mogorovich, Maurizio DE Maria, Ugo Boggi, Cesare Selli
BACKGROUND: Ureteral strictures occur in approximately 3-8% of kidney transplant (KTx) recipients. They are usually a late event which needs surgical re-intervention with a subsequent increased risk of graft loss. This retrospective study presents a single-centre experience in managing ureteral complications using firstly a minimally invasive approach. METHODS: Between January 2000 and November 2012, 838 patients underwent KTx with Lich-Gregoire uretero-vesical anastomosis...
May 11, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28479766/novel-technique-of-laparoscopic-extravesical-ureteric-reimplantation-in-primary-obstructive-megaureter
#6
Altaf Khan, Mujeebu Rahiman, Ashish Verma, Rahul Bhargava
OBJECTIVE: This study aims to demonstrate a novel laparoscopic technique of tapering megaureter without disrupting the blood supply and disconnecting the ureter. MATERIALS AND METHODS: Eight cases of primary obstructive megaureter in the age group of 14-22 years underwent laparoscopic extravesical ureteric reimplantation between August 2011 and July 2015 using our novel technique. Five patients had obstruction on left side and three on right side. Follow-up ultrasonography at 1 month and 3 months, voiding cystourethrogram (VCUG) at 3 months and intravenous urogram (IVU) at 6 months was obtained to assess the development of reflux and to look for adequate drainage of the obstructive ureter...
April 2017: Urology Annals
https://www.readbyqxmd.com/read/28476680/an-inguinal-approach-to-complex-extravesical-ureteral-reimplantation
#7
Adam S Howe, Lane S Palmer
OBJECTIVE: To report our experience in applying the Lich-Gregoir extravesical ureteral reimplantation (EVR) approach to complex cases (megaureter, duplex systems) through a small inguinal incision, with the goal of minimizing invasiveness. MATERIALS & METHODS: We reviewed the records of all patients who underwent common sheath and/or tapered EVR through an inguinal incision. Patient characteristics and reflux grade were obtained, and outcomes were assessed. The technique involved a 2 cm incision made in the lowest inguinal skin crease, standard cord exposure and lateral retraction, opening the floor of the canal to isolate the ureter...
May 2, 2017: Urology
https://www.readbyqxmd.com/read/28461998/detection-of-early-dj-stent-encrustation-by-sonographic-twinkling-artifacts-a-pilot-study
#8
Roman A Blaheta, Anton Oertl, Hans-Joachim Freisleben, Karen Nelson, Hanns Ackermann, Axel Haferkamp, Tobias Engl
INTRODUCTION: Ureter obstruction caused by a retro-peritoneal tumor is treated by inserting an indwelling ureter splint (DJ-stent). Indwelling duration is limited by cumulative crystalline deposits into the splint, eventually causing the repeated impairment of urine flow. Deciding when a DJ-stent must be replaced is important since belated removal can be accompanied by severe complications. X-ray or conventional sonography do not allow satisfactory evaluation of early incrustation, therefore, the use of sonographic twinkling artifacts (TA) to provide accurate stent surveillance was investigated...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28433070/effects-of-nicorandil-on-renal-function-and-histopathology-in-rats-with-partial-unilateral-ureteral-obstruction
#9
Hayrettin Ozturk, Tulin Firat, Buket Kin Tekce, Fahri Yilmaz, Hulya Ozturk
To evaluate the effects of nicorandil in a rat kidney model of partial unilateral ureteral obstruction (PUUO). Thirty male rats were randomly divided into three groups as follows: (1) Group 1 (Sham-control), ureters of the rats were manipulated but not ligated; (2) Group 2 (PUUO-untreated), PUUO was performed with two-thirds of the left ureter embedded in the psoas muscle; and (3) Group 3 (PUUO-nicorandil treated). After PUUO was established, nicorandil (15 mg/kg/day) was administered by gastric lavage for 21 days to determine its effects on PUUO-induced histopathological-, functional-, and oxidative stress-induced changes...
May 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28422037/ureteral-meatotomy-as-an-option-in-the-management-of-primary-obstructive-megaureter-in-neonates-and-infants
#10
Priscila Cardoso Braz, Fernanda Ghilardi Leão, Jovelino Quintino de Souza Leão, Luciano Silveira Onofre, Giselle Machado Campos de Oliveira, José Carnevale, Carlos Miguélez Lago
Differentiating between the cases of megaureter that require surgery and the ones in whom treatment can be delayed is challenging. A large number of surgical techniques for the treatment of POM been proposed aiming mainly to reduce renal damage by relieving the affected ureter. Resection of the affected ureteral segment followed by vesicoureteral reimplantation either with or without reduction ureteroplasty is the classic treatment, however posing a high rate of complications when performed in patients aged less than one year...
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28403495/-diagnosis-and-therapeutic-management-in-kidney-ureter-and-bladder-trauma
#11
Karin Hirsch, Marco Heinz, Bernd Wullich
Trauma refers to the destruction of tissues or organs by external forces and it is the most common cause of mortality and morbidity in children (1, 2). Injuries of the genitourinary tract may be the result of blunt (falls, sport injuries, motor vehicle accidents and sexual abuse) or penetrating (stab wounds, gun shots, falling onto sharp objects) injuries. The genitourinary tract is significantly injured in 2.9% of paediatric trauma patients 4.In the paediatric population, the kidney is the most affected organ in the genitourinary tract (>60% of all genitourinary tract injuries) 4...
February 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28396839/inhibition-of-the-tgf%C3%AE-signalling-pathway-by-cgmp-and-cgmp-dependent-kinase-i-in-renal-fibrosis
#12
Elisabeth Schinner, Veronika Wetzl, Andrea Schramm, Frieder Kees, Peter Sandner, Johannes-Peter Stasch, Franz Hofmann, Jens Schlossmann
Agents that enhance production of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) ameliorate the progression of renal fibrosis. However, the molecular mechanism of this process is not fully understood. We hypothesize that the antifibrotic effects of cGMP and cGMP-dependent kinase I (cGKI) are mediated via regulation of the TGFβ signalling pathway, both via ERK and the Smad-dependent route. Kidney fibrosis was induced by unilateral ureter obstruction (UUO) in wild-type and cGKI-deficient (cGKI-KO) mice...
April 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/28394518/-the-study-of-effectiveness-of-polyhydroxyalkanoates-based-biodegradable-stents-in-ureteropelvic-segment-pyeloplasty
#13
M P Myltygashev, A N Boyandin, A A Shumilova, F P Kapsargin, E I Shishatskaya, A K Kirichenko, T G Volova
INTRODUCTION: Among urologic diseases, ureteropelvic segment stenosis with hydronephrosis is a common indication for instrumental or surgical correction. The restriction of urine flow with dilatation proximal to obstruction develops in 6.5-37% of cases at different times after the ureteral reconstruction. All this urges to develop and improve stents and search for effective ways to place stents and control their function. AIM: To investigate the effectiveness of polyhydroxyalkanoates based biodegradable stent compared with a commercial analogue in upper urinary tract drainage after ureteropelvic segment pyeloplasty...
April 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28394517/-technical-features-of-intestinal-ureteroplasty-art-6-simultaneous-ureteral-and-bladder-substitution
#14
B K Komyakov, A I Novikov, V A Ochelenko, B G Guliev, T Kh Al-Attar, M V Onoshko
AIM: To present the results and technical features of different methods of simultaneous ileal ureteral and bladder substitution. MATERIALS AND METHODS: From 2001 to 2016, 154 patients (mean age 52+/-9.2 years) underwent ileal and appendicular ureteroplasty. Of them, 70 (45.4%) were men and 84 (54.6%) women. Among them, 49 (31.8%) patients underwent ureteroplasty concurrently with orthotopic ileocystoplasty. The Studers ileal-ureter cystoplasty and Y-shaped bladder and ureteral reconstruction were performed in 38 (77...
April 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28393852/omega-3-polyunsaturated-fatty-acids-attenuate-fibroblast-activation-and-kidney-fibrosis-involving-mtorc2-signaling-suppression
#15
Zhifeng Zeng, Haiyuan Yang, Ying Wang, Jiafa Ren, Yifan Dai, Chunsun Dai
Epidemiologic studies showed the correlation between the deficiency of omega-3 polyunsaturated fatty acids (n-3 PUFAs) and the progression of chronic kidney diseases (CKD), however, the role and mechanisms for n-3 PUFAs in protecting against kidney fibrosis remain obscure. In this study, NRK-49F cells, a rat kidney interstitial fibroblast cell line, were stimulated with TGFβ1. A Caenorhabditis elegans fat-1 transgenic mouse model in which n-3 PUFAs are endogenously produced from n-6 PUFAs owing to the expression of n-3 fatty acid desaturase were deployed...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28389594/giant-fibroepithelial-polyp-of-the-ureter
#16
Mayank Gupta, Sanjeet Roy, Cornerstone Wann, Anu Eapen
Giant fibroepithelial polyp is a rare cause of ureteric/ureteropelvic junction (UPJ) obstruction. We report a rare case of giant fibroepithelial polyp in a 32-year-old woman involving the whole length of the ureter, reaching up to the UPJ which was clinically and radiologically considered to be urothelial carcinoma. Frozen section showed a polypoid lesion lined by urothelium with no evidence of dysplasia or malignancy. Subsequently, nephroureterectomy was done as there was marked renal hydronephrosis and it was impossible to separate the polyp from the wall of the ureter...
April 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28388304/laparoscopic-ureteroureterostomy-with-an-intraoperative-retrograde-ureteroscopy-assisted-technique-for-distal-ureteral-injury-secondary-to-gynecological-surgery-a-retrospective-comparison-with-laparoscopic-ureteroneocystostomy
#17
Zhaohui Wang, Zhi Chen, Yao He, Bingsheng Li, Zhiqiang Wen, Xiang Chen
OBJECTIVES: The aim of this study was to compare the operative and postoperative outcomes of laparoscopic ureteroureterostomy (LAP-UU) using a retrograde ureteroscopy-assisted technique with laparoscopic ureteroneocystostomy (LAP-UNC) in treating ureteral injury after gynecological surgery. MATERIALS AND METHODS: The study analyzed 60 ureteral injury repairs performed between May 2010 and February 2016 in patients who underwent either LAP-UU using the retrograde ureteroscopy-assisted technique (n = 26) or LAP-UNC (n = 34)...
April 7, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28320713/antimicrobial-percutaneous-nephrostomy-catheters-for-the-prevention-of-renal-infections-in-vitro-studies
#18
Nylev Vargas-Cruz, Ruth A Reitzel, Joel Rosenblatt, Mohamed Jamal, Ariel D Szvalb, Anne-Marie Chaftari, Ray Hachem, Issam Raad
Purpose - Percutaneous nephrostomy (PCN) catheters are the primary method for draining ureters obstructed by malignancy and preventing a decline of the renal function. However, PCN-related infections such as pyelonephritis and urosepsis remain a significant concern. Currently no antimicrobial PCNs are available for preventing infectious complications. Vascular catheters impregnated with Minocycline/Rifampin (M/R) and M/R with Chlorhexidine coating (M/R+CHD) have previously demonstrated antimicrobial activity...
March 20, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28306195/influence-of-caudal-block-on-postoperative-oliguria-in-infants-undergoing-bilateral-ureteroneocystostomy-a-retrospective-analysis
#19
Hyun Jeong Lee, Yong Seon Choi, Bon-Nyeo Koo, Sang Won Han, Young Eun Cho, Young Jae Im, Jae Hoon Lee
BACKGROUND: Caudal block has been widely used in children undergoing genitourinary surgery. However, the influence of caudal block on postoperative oliguria is unclear. AIM: The aim of this study was to assess the effect of caudal block on urinary flow through the reimplanted ureter after ureteroneocystostomy and the incidence of postoperative oliguria in infants. METHODS: This retrospective study analyzed the medical records of 121 infants aged less than 12 months who underwent bilateral ureteroneocystostomy for vesicoureteral reflux at a tertiary medical center...
March 17, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28299237/asymptomatic-urolithiasis-complicated-by-nephrocutaneous-fistula
#20
Marion Hamard, Gaël Amzalag, Christoph D Becker, Pierre-Alexandre Poletti
Asymptomatic spontaneous nephrocutaneous fistula is a rare and severe complication of chronic urolithiasis. We report a case of 56-year-old woman with a nephrocutaneous fistula (NFC) which developed from a superinfected urinoma following calyceal rupture due to an obstructing calculus in the left ureter. The patient was clinically asymptomatic and came to the emergency department for a painless left flank fluctuating mass. This urinoma was superinfected, with a delayed development of renal abscesses and perirenal phlegmon found on contrast-enhanced uro-computed tomography (CT), responsible for left renal vein thrombophlebitis and left psoas abscess...
2017: Journal of Clinical Imaging Science
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