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https://www.readbyqxmd.com/read/28600487/fluid-viscoelasticity-promotes-collective-swimming-of-sperm
#1
Chih-Kuan Tung, Chungwei Lin, Benedict Harvey, Alyssa G Fiore, Florencia Ardon, Mingming Wu, Susan S Suarez
From flocking birds to swarming insects, interactions of organisms large and small lead to the emergence of collective dynamics. Here, we report striking collective swimming of bovine sperm in dynamic clusters, enabled by the viscoelasticity of the fluid. Sperm oriented in the same direction within each cluster, and cluster size and cell-cell alignment strength increased with viscoelasticity of the fluid. In contrast, sperm swam randomly and individually in Newtonian (nonelastic) fluids of low and high viscosity...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28566887/wall-shear-stress-in-portal-vein-of-cirrhotic-patients-with-portal-hypertension
#2
Wei Wei, Yan-Song Pu, Xin-Kai Wang, An Jiang, Rui Zhou, Yu Li, Qiu-Juan Zhang, Ya-Juan Wei, Bin Chen, Zong-Fang Li
AIM: To investigate wall shear stress (WSS) magnitude and distribution in cirrhotic patients with portal hypertension using computational fluid dynamics. METHODS: Idealized portal vein (PV) system models were reconstructed with different angles of the PV-splenic vein (SV) and superior mesenteric vein (SMV)-SV. Patient-specific models were created according to enhanced computed tomography images. WSS was simulated by using a finite-element analyzer, regarding the blood as a Newtonian fluid and the vessel as a rigid wall...
May 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28512313/a-rapid-capillary-pressure-driven-micro-channel-to-demonstrate-newtonian-fluid-behavior-of-zebrafish-blood-at-high-shear-rates
#3
Juhyun Lee, Tzu-Chieh Chou, Dongyang Kang, Hanul Kang, Junjie Chen, Kyung In Baek, Wei Wang, Yichen Ding, Dino Di Carlo, Yu-Chong Tai, Tzung K Hsiai
Blood viscosity provides the rheological basis to elucidate shear stress underlying developmental cardiac mechanics and physiology. Zebrafish is a high throughput model for developmental biology, forward-genetics, and drug discovery. The micro-scale posed an experimental challenge to measure blood viscosity. To address this challenge, a microfluidic viscometer driven by surface tension was developed to reduce the sample volume required (3μL) for rapid (<2 min) and continuous viscosity measurement. By fitting the power-law fluid model to the travel distance of blood through the micro-channel as a function of time and channel configuration, the experimentally acquired blood viscosity was compared with a vacuum-driven capillary viscometer at high shear rates (>500 s(-1)), at which the power law exponent (n) of zebrafish blood was nearly 1 behaving as a Newtonian fluid...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28445861/the-application-of-silicon-sol-gel-technology-to-forensic-blood-substitute-development-investigation-of-the-spreading-dynamics-onto-a-paper-surface
#4
Theresa Stotesbury, Mike Illes, Paul Wilson, Andrew J Vreugdenhil
This work investigates the spreading dynamics of three candidate sol-gel solutions, of ranging viscosities, surface tensions and densities, and compares them with water and two commercial blood substitute products. Droplets were created with different sizes (10 to75μL) and impact velocities (1.4 to 6.0m/s) to strike 176gsm cardstock. Over 2200 droplets were created using the six different fluids and their final dried stain diameter was measured. Droplet spread was plotted using the Scheller and Bousfield correlation and uses effective viscosity as a parameter for non-Newtonian fluids...
April 1, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28375423/front-microrheology-of-the-non-newtonian-behaviour-of-blood-scaling-theory-of-erythrocyte-aggregation-by-aging
#5
C Trejo-Soto, E Costa-Miracle, I Rodriguez-Villarreal, J Cid, M Castro, T Alarcon, A Hernandez-Machado
We introduce a new framework to study the non-Newtonian behaviour of fluids at the microscale based on the analysis of front advancement. We apply this methodology to study the non-linear rheology of blood in microchannels. We carry out experiments in which the non-linear viscosity of blood samples is quantified at different haematocrits and ages. Under these conditions, blood exhibits a power-law dependence on the shear rate. In order to analyse our experimental data, we put forward a scaling theory which allows us to define an adhesion scaling number...
April 19, 2017: Soft Matter
https://www.readbyqxmd.com/read/28367643/computational-fluid-dynamics-in-abdominal-aorta-bifurcation-non-newtonian-versus-newtonian-blood-flow-in-a-real-case-study
#6
Armando A Soares, Sílvia Gonzaga, Carlos Oliveira, André Simões, Abel I Rouboa
Hemodynamic in abdominal aorta bifurcation was investigated in a real case using computational fluid dynamics. A Newtonian and non-Newtonian (Walburn-Schneck) viscosity models were compared. The geometrical model was obtained by 3D reconstruction from CT-scan and hemodynamic parameters obtained by laser-Doppler. Blood was assumed incompressible fluid, laminar flow in transient regime and rigid vessel wall. Finite volume-based was used to study the velocity, pressure, wall shear stress (WSS) and viscosity throughout cardiac cycle...
April 3, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28343891/an-investigation-on-the-effects-of-the-angles-between-the-mitral-and-aortic-orifice-during-diastolic-period-using-fsi
#7
Md Shamsul Arefin
BACKGROUND: It was well documented that the changes in the physiological structure of the heart can alter the hemodynamic behaviour of the human left ventricle. Although there were various imaging tools that can stipulate the blood flow characteristics inside the ventricle, but the effect of the variation in the angles between the mitral and aortic orifices were yet to be determined. Hence the primary focus of this paper was to use Fluid-Structure Interaction scheme throughout the diastolic phase to examine and determine the hemodynamic behaviour inside the cavity under various angles between the mitral and aortic orifices (50°, 55° and 60°)...
March 18, 2017: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/28268793/blood-viscosity-monitoring-during-cardiopulmonary-bypass-based-on-pressure-flow-characteristics-of-a-newtonian-fluid
#8
Shigeyuki Okahara, Zu Soh, Shinya Takahashi, Taijiro Sueda, Toshio Tsuji
We proposed a blood viscosity estimation method based on pressure-flow characteristics of oxygenators used during cardiopulmonary bypass (CPB) in a previous study that showed the estimated viscosity to correlate well with the measured viscosity. However, the determination of the parameters included in the method required the use of blood, thereby leading to high cost of calibration. Therefore, in this study we propose a new method to monitor blood viscosity, which approximates the pressure-flow characteristics of blood considered as a non-Newtonian fluid with characteristics of a Newtonian fluid by using the parameters derived from glycerin solution to enable ease of acquisition...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28258413/viscosity-and-haemodynamics-in-a-late-gestation-rat-feto-placental-arterial-network
#9
Nikhilesh Bappoo, Lachlan J Kelsey, Louis Parker, Tim Crough, Carmel M Moran, Adrian Thomson, Megan C Holmes, Caitlin S Wyrwoll, Barry J Doyle
The placenta is a transient organ which develops during pregnancy to provide haemotrophic support for healthy fetal growth and development. Fundamental to its function is the healthy development of vascular trees in the feto-placental arterial network. Despite the strong association of haemodynamics with vascular remodelling mechanisms, there is a lack of computational haemodynamic data that may improve our understanding of feto-placental physiology. The aim of this work was to create a comprehensive 3D computational fluid dynamics model of a substructure of the rat feto-placental arterial network and investigate the influence of viscosity on wall shear stress (WSS)...
March 3, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28249082/are-non-newtonian-effects-important-in-hemodynamic-simulations-of-patients-with-autogenous-fistula
#10
S M Javid Mahmoudzadeh Akherat, Kevin Cassel, Michael Boghosian, Promila Dhar, Mary Hammes
Given the current emphasis on accurate computational fluid dynamics (CFD) modeling of cardiovascular flows, which incorporates realistic blood vessel geometries and cardiac waveforms, it is necessary to revisit the conventional wisdom regarding the influences of non-Newtonian effects. In this study, patient-specific reconstructed 3D geometries, whole blood viscosity data, and venous pulses postdialysis access surgery are used as the basis for the hemodynamic simulations of renal failure patients with native fistula access...
April 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28226987/blood-viscosity-monitoring-during-cardiopulmonary-bypass-based-on-pressure-flow-characteristics-of-a-newtonian-fluid
#11
Shigeyuki Okahara, Zu Soh, Shinya Takahashi, Taijiro Sueda, Toshio Tsuji, Shigeyuki Okahara, Zu Soh, Shinya Takahashi, Taijiro Sueda, Toshio Tsuji, Zu Soh, Toshio Tsuji, Shinya Takahashi, Taijiro Sueda, Shigeyuki Okahara
We proposed a blood viscosity estimation method based on pressure-flow characteristics of oxygenators used during cardiopulmonary bypass (CPB) in a previous study that showed the estimated viscosity to correlate well with the measured viscosity. However, the determination of the parameters included in the method required the use of blood, thereby leading to high cost of calibration. Therefore, in this study we propose a new method to monitor blood viscosity, which approximates the pressure-flow characteristics of blood considered as a non-Newtonian fluid with characteristics of a Newtonian fluid by using the parameters derived from glycerin solution to enable ease of acquisition...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28197271/low-density-lipoprotein-and-non-newtonian-oscillating-flow-biomechanical-parameters-for-normal-human-aorta
#12
Johannes V Soulis, Dimitrios K Fytanidis, Olga P Lampri, George D Giannoglou
BACKGROUND: The temporal variation of the hemodynamic mechanical parameters during cardiac pulse wave is considered as an important atherogenic factor. Applying non-Newtonian blood molecular viscosity simulation is crucial for hemodynamic analysis. Understanding low density lipoprotein (LDL) distribution in relation to flow parameters will possibly spot the prone to atherosclerosis aorta regions. METHODS: The biomechanical parameters tested were averaged wall shear stress (AWSS), oscillatory shear index (OSI) and relative residence time (RRT) in relation to the LDL concentration...
April 2016: Cardiology Research
https://www.readbyqxmd.com/read/28110718/heat-transfer-analysis-on-peristaltically-induced-motion-of-particle-fluid-suspension-with-variable-viscosity-clot-blood-model
#13
M M Bhatti, A Zeeshan, R Ellahi
In this article, heat transfer analysis on clot blood model of the particle-fluid suspension through a non-uniform annulus has been investigated. The blood propagating along the whole length of the annulus was induced by peristaltic motion. The effects of variable viscosity and slip condition are also taken into account. The governing flow problem is modeled using lubrication approach by taking the assumption of long wavelength and creeping flow regime. The resulting equation for fluid phase and particle phase is solved analytically and closed form solutions are obtained...
December 2016: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27941986/numerical-investigation-of-oxygenated-and-deoxygenated-blood-flow-through-a-tapered-stenosed-arteries-in-magnetic-field
#14
M Y Abdollahzadeh Jamalabadi, Amin Ali Akbari Bidokhti, Hamid Khak Rah, Siavash Vaezi, Payam Hooshmand
Current paper is focused on transient modeling of blood flow through a tapered stenosed arteries surrounded a by solenoid under the presence of heat transfer. The oxygenated and deoxygenated blood are considered here by the Newtonian and Non-Newtonian fluid (power law and Carreau-Yasuda) models. The governing equations of bio magnetic fluid flow for an incompressible, laminar, homogeneous, non-Newtonian are solved by finite volume method with SIMPLE algorithm for structured grid. Both magnetization and electric current source terms are well thought-out in momentum and energy equations...
2016: PloS One
https://www.readbyqxmd.com/read/27908703/simultaneous-effects-of-coagulation-and-variable-magnetic-field-on-peristaltically-induced-motion-of-jeffrey-nanofluid-containing-gyrotactic-microorganism
#15
M M Bhatti, A Zeeshan, R Ellahi
In this article, simultaneous effects of coagulation (blood clot) and variable magnetic field on peristaltically induced motion of non-Newtonian Jeffrey nanofluid containing gyrotactic microorganism through an annulus have been studied. The effects of an endoscope also taken into consideration in our study as a special case. The governing flow problem is simplified by taking the approximation of long wavelength and creeping flow regime. The resulting highly coupled differential equations are solved analytically with the help of perturbation method and series solution have been presented up to second order approximation...
November 29, 2016: Microvascular Research
https://www.readbyqxmd.com/read/27879127/numerical-simulations-of-a-3d-fluid-structure-interaction-model-for-blood-flow-in-an-atherosclerotic-artery
#16
Oualid Kafi, Nader El Khatib, Jorge Tiago, Adelia Sequeira
The inflammatory process of atherosclerosis leads to the formation of an atheromatous plaque in the intima of the blood vessel. The plaque rupture may result from the interaction between the blood and the plaque. In each cardiac cycle, blood interacts with the vessel, considered as a compliant nonlinear hyperelastic. A three dimensional idealized fluid-structure interaction (FSI) model is constructed to perform the blood-plaque and blood-vessel wall interaction studies. An absorbing boundary condition (BC) is imposed directly on the outflow in order to cope with the spurious reflexions due to the truncation of the computational domain...
February 1, 2017: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/27874180/passive-drip-stain-formation-dynamics-of-blood-onto-hard-surfaces-and-comparison-with-simple-fluids-for-blood-substitute-development-and-assessment-sup
#17
Theresa Stotesbury, Michael C Taylor, Mark C Jermy
The spreading dynamics of blood dripping onto hard surfaces is compared to two spreading models. Samples of human blood, porcine blood, and Millipore(®) water were dripped onto cardboard, foamcore, and glass surfaces in low velocity passive drip simulations. Final stain diameter, the total number of spines and scallops, and angle of impact were measured and analyzed. Spreading is best predicted by applying the concept of effective viscosity to the Scheller and Bousfield (R(2)  = 0.91) and Roisman (R(2)  = 0...
January 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27791257/assessing-radiocephalic-wrist-arteriovenous-fistulas-of-obtuse-anastomosis-using-computational-fluid-dynamics-and-clinical-application
#18
Jinkee Lee, Sunho Kim, Sung-Min Kim, Ryungeun Song, Hyun Kyu Kim, Jang Sang Park, Sun Cheol Park
INTRODUCTION: A radiocephalic arteriovenous fistula (AVF) is the best choice for achieving vascular access (VA) for hemodialysis, but this AVF has high rates of early failure due to juxta-anastomotic stenosis, making it impossible to use for dialysis. Low hemodynamic shear stress contributes to the pathophysiology of VA failure due to secondary thrombosis, stenosis, and re-occlusion after percutaneous intervention. METHODS: We used a computational fluid dynamics (CFDs) approach to evaluate the shear stress distribution and minimize its effects under various conditions including changes in the anastomosis angle...
November 2, 2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/27761107/design-of-microfluidic-channels-for-magnetic-separation-of-malaria-infected-red-blood-cells
#19
Wei-Tao Wu, Andrea Blue Martin, Alberto Gandini, Nadine Aubry, Mehrdad Massoudi, James F Antaki
This study is motivated by the development of a blood cell filtration device for removal of malaria-infected, parasitized red blood cells (pRBCs). The blood was modeled as a multi-component fluid using the computational fluid dynamics discrete element method (CFD-DEM), wherein plasma was treated as a Newtonian fluid and the red blood cells (RBCs) were modeled as soft-sphere solid particles which move under the influence of drag, collisions with other RBCs, and a magnetic force. The CFD-DEM model was first validated by a comparison with experimental data from Han et al...
2016: Microfluidics and Nanofluidics
https://www.readbyqxmd.com/read/27738841/effects-of-flowing-rbcs-on-adhesion-of-a-circulating-tumor-cell-in-microvessels
#20
L L Xiao, Y Liu, S Chen, B M Fu
Adhesion of circulating tumor cells (CTCs) to the microvessel wall largely depends on the blood hydrodynamic conditions, one of which is the blood viscosity. Since blood is a non-Newtonian fluid, whose viscosity increases with hematocrit, in the microvessels at low shear rate. In this study, the effects of hematocrit, vessel size, flow rate and red blood cell (RBC) aggregation on adhesion of a CTC in the microvessels were numerically investigated using dissipative particle dynamics. The membrane of cells was represented by a spring-based network connected by elastic springs to characterize its deformation...
April 2017: Biomechanics and Modeling in Mechanobiology
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