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Newtonian fluid blood

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https://www.readbyqxmd.com/read/29736127/experimental-investigation-of-the-effect-of-non-newtonian-behavior-of-blood-flow-in-the-fontan-circulation
#1
Andrew L Cheng, Niema M Pahlevan, Derek G Rinderknecht, John C Wood, Morteza Gharib
The Fontan procedure for univentricular heart defects creates a unique circulation where all pulmonary blood flow is passively supplied directly from systemic veins. Computational simulations, aimed at optimizing the surgery, have assumed blood to be a Newtonian fluid without evaluating the potential error introduced by this assumption. We compared flow behavior between a non-Newtonian blood analog (0.04% xanthan gum) and a control Newtonian fluid (45% glycerol) in a simplified model of the Fontan circulation...
March 2018: European Journal of Mechanics. B, Fluids
https://www.readbyqxmd.com/read/29732048/the-computational-fluid-dynamics-analyses-on-hemodynamic-characteristics-in-stenosed-arterial-models
#2
Yue Zhou, Chunhian Lee, Jingying Wang
Arterial stenosis plays an important role in the progressions of thrombosis and stroke. In the present study, a standard axisymmetric tube model of the stenotic artery is introduced and the degree of stenosis η is evaluated by the area ratio of the blockage to the normal vessel. A normal case ( η = 0) and four stenotic cases of η = 0.25, 0.5, 0.625, and 0.75 with a constant Reynolds number of 300 are simulated by computational fluid dynamics (CFD), respectively, with the Newtonian and Carreau models for comparison...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29678730/interaction-between-blood-and-solid-particles-propagating-through-a-capillary-with-slip-effects
#3
A Zeeshan, A Fatima, F Khalid, M M Bhatti
This article describes the interaction between solid particles and blood propagating through a capillary. A slip condition is considered on the walls of the capillary. The rheological features of the blood are discussed by considering as a two-phase Newtonian fluid model, i.e., the suspension of cells in plasma. A perturbation method is successfully applied to obtain the series solution of the governing coupled differential equations. The series solution for both fluid and particle phase are presented up to second order approximation...
April 17, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29673936/comparison-between-a-generalized-newtonian-model-and-a-network-type-multiscale-model-for-hemodynamic-behavior-in-the-aortic-arch-validation-with-4d-mri-data-for-a-case-study
#4
Marine Menut, Loïc Boussel, Xavier Escriva, Benyebka Bou-Saïd, Hélène Walter-Le Berre, Yann Marchesse, Antoine Millon, Nellie Della Schiava, Patrick Lermusiaux, John Tichy
Blood is a complex fluid in which the presence of the various constituents leads to significant changes in its rheological properties. Thus, an appropriate non-Newtonian model is advisable; and we choose a Modified version of the rheological model of Phan-Thien and Tanner (MPTT). The different parameters of this model, derived from the rheology of polymers, allow characterization of the non-Newtonian nature of blood, taking into account the behavior of red blood cells in plasma. Using the MPTT model that we implemented in the open access software OpenFOAM, numerical simulations have been performed on blood flow in the thoracic aorta for a healthy patient...
March 29, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29603681/a-comparative-cfd-study-of-four-inferior-vena-cava-filters
#5
Josep M López, Gerard Fortuny, Dolors Puigjaner, Joan Herrero, Francesc Marimon
Computational fluid dynamics was used to simulate the flow of blood within an inferior vena cava (IVC) geometry model that was reconstructed from computed tomography images obtained from a real patient. The main novelty of the present work is that we simulated the implantation of four different filter models in this realistic IVC geometry. We considered different blood flow rates in the range between Vin =20 and Vin =80cm3 /s and all simulations were performed with both the Newtonian and a non-Newtonian model for the blood viscosity...
March 30, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29596861/numerical-simulation-of-heat-transfer-in-blood-flow-altered-by-electroosmosis-through-tapered-micro-vessels
#6
J Prakash, K Ramesh, D Tripathi, R Kumar
A numerical simulation is presented to study the heat and flow characteristics of blood flow altered by electroosmosis through the tapered micro-vessels. Blood is assumed as non-Newtonian (micropolar) nanofluids. The flow regime is considered as asymmetric diverging (tapered) microchannel for more realistic micro-vessels which is produced by choosing the peristaltic wave train on the walls to have different amplitudes and phase. The Rosseland approximation is employed to model the radiation heat transfer and temperatures of the walls are presumed constants...
March 26, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29561062/how-viscoelastic-is-human-blood-plasma
#7
S Varchanis, Y Dimakopoulos, C Wagner, J Tsamopoulos
Blood plasma has been considered a Newtonian fluid for decades. Recent experiments (Brust et al., Phys. Rev. Lett., 2013, 110) revealed that blood plasma has a pronounced viscoelastic behavior. This claim was based on purely elastic effects observed in the collapse of a thin plasma filament and the fast flow of plasma inside a contraction-expansion microchannel. However, due to the fact that plasma is a solution with very low viscosity, conventional rotational rheometers are not able to stretch the proteins effectively and thus, provide information about the viscoelastic properties of plasma...
March 21, 2018: Soft Matter
https://www.readbyqxmd.com/read/29489852/modeling-and-analysis-of-biomagnetic-blood-carreau-fluid-flow-through-a-stenosis-artery-with-magnetic-heat-transfer-a-transient-study
#8
Mohammad Yaghoub Abdollahzadeh Jamalabadi, Mohammadreza Daqiqshirazi, Hossein Nasiri, Mohammad Reza Safaei, Truong Khang Nguyen
We present a numerical investigation of tapered arteries that addresses the transient simulation of non-Newtonian bio-magnetic fluid dynamics (BFD) of blood through a stenosis artery in the presence of a transverse magnetic field. The current model is consistent with ferro-hydrodynamic (FHD) and magneto-hydrodynamic (MHD) principles. In the present work, blood in small arteries is analyzed using the Carreau-Yasuda model. The arterial wall is assumed to be fixed with cosine geometry for the stenosis. A parametric study was conducted to reveal the effects of the stenosis intensity and the Hartman number on a wide range of flow parameters, such as the flow velocity, temperature, and wall shear stress...
2018: PloS One
https://www.readbyqxmd.com/read/29488139/a-novel-plasma-based-fluid-for-particle-image-velocimetry-piv-in-vitro-feasibility-study-of-flow-diverter-effects-in-aneurysm-model
#9
Johanna Clauser, Marius S Knieps, Martin Büsen, Andreas Ding, Thomas Schmitz-Rode, Ulrich Steinseifer, Jutta Arens, Giorgio Cattaneo
Particle image velocimetry (PIV) is a commonly used method for in vitro investigation of fluid dynamics in biomedical devices, such as flow diverters for intracranial aneurysm treatment. Since it is limited to transparent blood substituting fluids like water-glycerol mixture, the influence of coagulation and platelet aggregation is neglected. We aimed at the development and the application of a modified platelet rich plasma as a new PIV fluid with blood-like rheological and coagulation properties. In standardized intracranial aneurysm silicone models, the effect of this new PIV plasma on the fluid dynamics before and after flow diverter implantation was evaluated and compared with water-glycerol measurements...
June 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29430274/direct-enrichment-of-pathogens-from-physiological-samples-of-high-conductivity-and-viscosity-using-h-filter-and-positive-dielectrophoresis
#10
Dongyang Cai, Qiaolian Yi, Chaohua Shen, Ying Lan, Gerald Urban, Wenbin Du
The full potential of microfluidic techniques as rapid and accurate methods for the detection of disease-causing agents and foodborne pathogens is critically limited by the complex sample preparation process, which commonly comprises the enrichment of bacterial cells to detectable levels. In this manuscript, we describe a microfluidic device which integrates H-filter desalination with positive dielectrophoresis (pDEP) for direct enrichment of bacterial cells from physiological samples of high conductivity and viscosity, such as cow's milk and whole human blood...
January 2018: Biomicrofluidics
https://www.readbyqxmd.com/read/29427440/investigation-of-pumping-mechanism-for-non-newtonian-blood-flow-with-ac-electrothermal-forces-in-a-microchannel-by-hybrid-boundary-element-method-and-immersed-boundary-lattice-boltzmann-method
#11
Qinlong Ren
Efficient pumping of blood flow in a microfluidic device is essential for rapid detection of bacterial bloodstream infections (BSI) using alternating current (AC) electrokinetics. Compared with AC electro-osmosis (ACEO) phenomenon, the advantage of AC electrothermal (ACET) mechanism is its capability of pumping biofluids with high electrical conductivities at a relatively high AC voltage frequency. In the current work, the microfluidic pumping of non-Newtonian blood flow using ACET forces is investigated in detail by modeling its multi-physics process with hybrid boundary element method (BEM) and immersed boundary-lattice Boltzmann method (IB-LBM)...
February 10, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29423504/nonlinear-dynamics-of-dacron-aortic-prostheses-conveying-pulsatile-flow
#12
Eleonora Tubaldi, Michael P Païdoussis, Marco Amabili
This study addresses the dynamic response to pulsatile physiological blood flow and pressure of a woven Dacron graft currently used in thoracic aortic surgery. The model of the prosthesis assumes a cylindrical orthotropic shell described by means of nonlinear Novozhilov shell theory. The blood flow is modeled as Newtonian pulsatile flow, and unsteady viscous effects are included. Coupled fluid-structure Lagrange equations for open systems with wave propagation subject to pulsatile flow are applied. Physiological waveforms of blood pressure and velocity are approximated with the first eight harmonics of the corresponding Fourier series...
June 1, 2018: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29409057/endothelial-shear-stress-5-years-after-implantation-of-a-coronary-bioresorbable-scaffold
#13
Vikas Thondapu, Erhan Tenekecioglu, Eric K W Poon, Carlos Collet, Ryo Torii, Christos V Bourantas, Cheng Chin, Yohei Sotomi, Hans Jonker, Jouke Dijkstra, Eve Revalor, Frank Gijsen, Yoshinobu Onuma, Andrew Ooi, Peter Barlis, Patrick W Serruys
Aims: As a sine qua non for arterial wall physiology, local hemodynamic forces such as endothelial shear stress (ESS) may influence long-term vessel changes as bioabsorbable scaffolds dissolve. The aim of this study was to perform serial computational fluid dynamic (CFD) simulations to examine immediate and long-term haemodynamic and vascular changes following bioresorbable scaffold placement. Methods and results: Coronary arterial models with long-term serial assessment (baseline and 5 years) were reconstructed through fusion of intravascular optical coherence tomography and angiography...
February 2, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29305878/study-of-microvascular-non-newtonian-blood-flow-modulated-by-electroosmosis
#14
Dharmendra Tripathi, Ashu Yadav, O Anwar Bég, Rakesh Kumar
An analytical study of microvascular non-Newtonian blood flow is conducted incorporating the electro-osmosis phenomenon. Blood is considered as a Bingham rheological aqueous ionic solution. An externally applied static axial electrical field is imposed on the system. The Poisson-Boltzmann equation for electrical potential distribution is implemented to accommodate the electrical double layer in the microvascular regime. With long wavelength, lubrication and Debye-Hückel approximations, the boundary value problem is rendered non-dimensional...
May 2018: Microvascular Research
https://www.readbyqxmd.com/read/29249336/pulsatile-flow-of-non-newtonian-blood-fluid-inside-stenosed-arteries-investigating-the-effects-of-viscoelastic-and-elastic-walls-arteriosclerosis-and-polycythemia-diseases
#15
A Abbas Nejad, Z Talebi, D Cheraghali, A Shahbani-Zahiri, M Norouzi
BACKGROUND AND OBJECTIVE: In this study, the interaction of pulsatile blood flow with the viscoelastic walls of the axisymmetric artery is numerically investigated for different severities of stenosis. The geometry of artery is modeled by an axisymmetric cylindrical tube with a symmetric stenosis in a two-dimensional case. The effects of stenosis severity on the axial velocity profile, pressure distribution, streamlines, wall shear stress, and wall radial displacement for the viscoelastic artery are also compared to the elastics artery...
February 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29247703/effects-of-tiotropium-bromide-on-airway-hyperresponsiveness-and-inflammation-in-mice-exposed-to-organic-dust
#16
Joshua A Gregory, Cecilia Kemi, Jie Ji, Jakob Karén, Ingrid Delin, Per Gerde, Michael P Pieper, Mikael Adner, Kjell Larsson
INTRODUCTION: Acute exposure to organic dust (OD) in pig barns induces intense airway inflammation with neutrophilia and hyperresponsiveness. This reaction is likely associated with increased cholinergic activity. Therefore, the involvement of cholinergic mechanisms in the reaction to acute exposure of OD was investigated in mice using the long-acting muscarinic antagonist tiotropium. METHODS: BALB/c mice received tiotropium (2-200 ng) intranasally on day 1 of the study...
February 2018: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29235874/effect-of-wetting-on-drop-splashing-of-newtonian-fluids-and-blood
#17
T C de Goede, N Laan, K G de Bruin, D Bonn
We investigate the impact velocity beyond which the ejection of smaller droplets from the main droplet (splashing) occurs for droplets of different liquids impacting different smooth surfaces. We examine its dependence on the surface wetting properties and droplet surface tension. We show that the splashing velocity is independent of the wetting properties of the surface but increases roughly linearly with increasing surface tension of the liquid. A preexisting splashing model and simplification are considered that predict the splashing velocity by incorporating the air viscosity...
December 26, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29205216/investigation-of-blood-flow-rheology-using-second-grade-viscoelastic-model-phan-thien-tanner-within-carotid-artery
#18
Abas Ramiar, Morsal Momenti Larimi, Ali Akbar Ranjbar
PURPOSE: Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. The fluid is considered to be non-Newtonian, whose flow is governed by the equation of a second-grade viscoelastic fluid and the effects of viscoelastic on blood flow in carotid artery is investigated. METHODS: Pulsatile flow studies were carried out in a 3D model of carotid artery...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29197751/dacron-graft-as-replacement-to-dissected-aorta-a-three-dimensional-fluid-structure-interaction-analysis
#19
R Jayendiran, B M Nour, A Ruimi
Aortic dissection (AD) is a serious medical condition characterized by a tear in the intima, the inner layer of the aortic walls. In such occurrence, blood is being diverted to the media (middle) layer and may result in patient death if not quickly attended. In the case where the diseased portion of the aorta needs to be replaced, one common surgical technique is to use a graft made of Dacron, a synthetic fabric. We investigate the response of a composite human aortic segment-Dacron graft structure subjected to blood flow using the three-dimensional fluid-structure-interaction (FSI) capability in Abaqus...
February 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29159532/a-multiphysics-approach-for-modeling-early-atherosclerosis
#20
M P Thon, A Hemmler, A Glinzer, M Mayr, M Wildgruber, A Zernecke-Madsen, M W Gee
This work is devoted to the development of a mathematical model of the early stages of atherosclerosis incorporating processes of all time scales of the disease and to show their interactions. The cardiovascular mechanics is modeled by a fluid-structure interaction approach coupling a non-Newtonian fluid to a hyperelastic solid undergoing anisotropic growth and a change of its constitutive equation. Additionally, the transport of low-density lipoproteins and its penetration through the endothelium is considered by a coupled set of advection-diffusion-reaction equations...
November 20, 2017: Biomechanics and Modeling in Mechanobiology
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