keyword
MENU ▼
Read by QxMD icon Read
search

Follicular

keyword
https://www.readbyqxmd.com/read/29667951/copanlisib-aliqopa-for-relapsed-follicular-lymphoma
#1
(no author information available yet)
No abstract text is available yet for this article.
April 23, 2018: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/29667147/effects-of-heyan-kuntai-capsule-on-follicular-development-and-oocyte-cohesin-levels-in-aged-mice
#2
Bin Zhang, Nan Chu, Xue-Min Qiu, Wei Tang, Hans-Jürgen Gober, Da-Jin Li, Ling Wang
OBJECTIVE: To evaluate the effect of Heyan Kuntai Capsule (, HYKT) on the ovarian function of aged mice and expressions of cohesion complexes in oocytes. METHODS: Twenty-five 9-month-old female C57BL/6J mice were randomly divided into 5 groups by block randomization method (n=5 per group), including the control group (saline), 17 β-estradiol group [E2 , 100 μg/(kg·d)], and low-, medium-, and high-dose of HYKT groups [0.3, 0.9, 2.7 g/(kg·d), respectively]. All mice were treated by intragastric administration for 4 weeks...
April 17, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29666959/carney-complex-a-case-with-thyroid-follicular-adenoma-without-a-prkar1a-mutation
#3
Shinji Hattori, Yukou Yamane, Ryoichi Shimomura, Yuki Uchida, Nobuhiko Toyota, Yoshio Miura, Setsujyo Shiota, Yoshitsugu Tajima
BACKGROUND: Carney complex (CNC) is a very rare disease. Although thyroid lesions are included in the diagnostic criteria for CNC, they are an infrequent occurrence. CASE PRESENTATION: The patient was a 69-year-old woman who had undergone the removal of a left atrial myxoma 10 years earlier, at the age of 59. At the time of the operation, thyroid ultrasonography (US) revealed multiple hypoechoic nodules. Thyroid scintigraphy revealed an increased uptake of 99m Tc in these lesions, which was consistent with toxic multinodular goiter, and she was diagnosed with CNC...
April 17, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29666264/correction-for-serr-et-al-mirna92a-targets-klf2-and-the-phosphatase-pten-signaling-to-promote-human-t-follicular-helper-precursors-in-t1d-islet-autoimmunity
#4
(no author information available yet)
No abstract text is available yet for this article.
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29666170/serum-25-hydroxyvitamin-d-levels-throughout-pregnancy-a-longitudinal-study-in-healthy-and-preeclamptic-pregnant-women
#5
Yessica Agudelo-Zapata, Luis Miguel Maldonado-Acosta, Hector Fabio Sandoval-Alzate, Natalia Elvira Poveda, María Fernanda Garcés, Jonathan Alexander Cortés-Vásquez, Andrés Felipe Linares-Vaca, Carlos Alejandro Mancera-Rodríguez, Shahar Alexandra Perea-Ariza, Karen Yuliana Ramírez-Iriarte, Camilo Andrés Castro-Saldarriaga, Juan Manuel Arteaga-Diaz, Roberto Franco-Vega, Edith Angel-Muller, Arturo José Parada-Baños, Jorge Eduardo Caminos
BACKGROUND: Worldwide there is a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency, and has been associated with adverse outcomes during pregnancy. OBJECTIVE: This is a nested, case-control study in a longitudinal cohort to compare the serum 25OHD levels and other biomarkers throughout pregnancy in a group of 20 preeclamptic women and 61 healthy pregnant women. An additional group of 29 healthy non-pregnant women were also studied during the two phases of the menstrual cycle...
April 17, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29666118/a-simplified-scoring-system-in-de-novo-follicular-lymphoma-treated-initially-with-immunochemotherapy
#6
Emmanuel Bachy, Matthew J Maurer, Thomas M Habermann, Bénédicte Gelas-Dore, Delphine Maucort-Boulch, Jane A Estell, Eric Van den Neste, Réda Bouabdallah, Emmanuel Gyan, Andrew L Feldman, Joan Bargay, Alain Delmer, Susan L Slager, Maria Gomes da Silva, Olivier Fitoussi, David Belada, Hervé Maisonneuve, Tanin Intragumtornchai, Stephen M Ansell, Thierry Lamy, Peggy Dartigues, Brian K Link, John F Seymour, James R Cerhan, Gilles Salles
In follicular lymphoma (FL), no prognostic index has been built based solely on a cohort of patients treated with initial immunochemotherapy. There is currently a need to define parsimonious clinical models for trial stratification and to add on biomolecular factors. Here, we confirmed the validity of both the FLIPI and the FLIPI2 in the large prospective PRIMA trial cohort of 1,135 patients treated with initial R-chemotherapy +/- R maintenance. Furthermore, we developed a new prognostic tool comprising only 2 simple parameters (bone marrow involvement and β2-microglobulin (β2m)) to predict progression-free survival (PFS)...
April 17, 2018: Blood
https://www.readbyqxmd.com/read/29666117/novel-insights-into-the-pathogenesis-of-t-cell-lymphomas
#7
John S Van Arnam, Megan S Lim, Kojo S J Elenitoba-Johnson
T-cell lymphomas are a heterogeneous group of rare malignancies with overlapping clinical, immunologic and histologic features. Recent advances in our understanding of T-cell differentiation based on gene expression profiling, next-generation sequencing (NGS) and transgenic mouse modeling studies have better elucidated the pathogenetic mechanisms underlying the diverse biology of T-cell lymphomas. These studies show that while genetic alterations in epigenetic modifiers are implicated in all subtypes of T-cell lymphomas, specific subtypes demonstrate enrichment for particular recurrent alterations targeting specific genes...
April 17, 2018: Blood
https://www.readbyqxmd.com/read/29666116/critical-influences-on-the-pathogenesis-of-follicular-lymphoma
#8
Ralf Küppers, Freda K Stevenson
The development of follicular lymphoma (FL) from a founder B cell with an upregulation of BCL2, via the t(14;18) translocation, to a proliferating clone, poised to undergo further transformation to an aggressive lymphoma, illustrates the opportunistic Darwinian process of tumorigenesis. Protection against apoptosis allows an innocent cell to persist and divide, with dangerous accumulation of further mutational changes, commonly involving inactivation of chromatin-modifying genes. But this is not all. FL cells reflect normal B cells in relying on expression of surface Ig...
April 17, 2018: Blood
https://www.readbyqxmd.com/read/29666007/mutation-analysis-of-therapy-related-myeloid-neoplasms
#9
Takahiro Nishiyama, Yuichi Ishikawa, Naomi Kawashima, Akimi Akashi, Yoshiya Adachi, Hikaru Hattori, Yoko Ushijima, Hitoshi Kiyoi
We analyzed the genetic mutation status of 13 patients with therapy-related myeloid neoplasms (t-MN). Consistent with previous reports, t-MN cells preferentially acquired mutations in TP53 and epigenetic modifying genes, instead of mutations in tyrosine kinase and spliceosome genes. Furthermore, we compared the mutation status of three t-MN cells with each of the initial lymphoid malignant cells, and identified common mutations among t-MN and the initial malignant cells in two patients. In a patient who developed chronic myelomonocytic leukemia (CMML) after follicular lymphoma (FL), TET2 mutation was identified in both CMML and FL cells...
April 2018: Cancer Genetics
https://www.readbyqxmd.com/read/29665631/primary-colonic-follicular-lymphoma-presenting-as-four-diminutive-sessile-polyps-found-incidentally-during-colonoscopy
#10
Sun Jin, Hyun Seok Lee, Ji Yun Jeong, Young Wook Jo
Follicular lymphomas, which typically arise in the lymph nodes with spleen, liver, and bone marrow involvement, have generally low occurrence rates in Asian countries as compared with Western countries. Follicular lymphomas of the gastrointestinal tract are rare, and primary colonic follicular lymphomas are particularly rare compared with others found in the small intestine and duodenum. Colonoscopic imaging of colonic lymphomas, including follicular lymphoma, may reveal mucosal ulcerations, erosions, indurations, polypoid mass-like lesions, and diffuse mucosal nodularity...
April 18, 2018: Clinical Endoscopy
https://www.readbyqxmd.com/read/29665451/tgf-%C3%AE-1-resulting-in-differential-microrna-expression-in-bovine-granulosa-cells
#11
Yefen Xu, Jiaqiang Niu, Guangying Xi, Xuezhi Niu, Yuheng Wang, Ming Guo, Qiangba Yangzong, Yilong Yao, Suolang Sizhu, Jianhui Tian
To explore the expression profile of the cellular miRNAs in bovine ovarian granulosa cells responding to transforming growth factor-β1 (TGF-β1), the effect of TGF-β1 on cell proliferation was firstly investigated by CCK-8 method and the results showed that there was a significant inhibitory effect on bovine granulosa cell proliferation treated with 5/10 ng/mL human recombinant TGF-β1 for 24 h compared to the control (P < 0.05). Then, we performed high-throughput sequencing of two small RNA libraries prepared from cultured bovine granulosa cells stimulated with or without 10 ng/mL human recombinant TGF-β1...
April 14, 2018: Gene
https://www.readbyqxmd.com/read/29665320/reduced-lymphotoxin-beta-production-by-tumour-cells-is-associated-with-loss-of-follicular-dendritic-cell-phenotype-and-diffuse-growth-in-follicular-lymphoma
#12
Giuseppina Pepe, Arianna Di Napoli, Claudia Cippitelli, Stefania Scarpino, Emanuela Pilozzi, Luigi Ruco
Cytokine production is essential for follicular dendritic cell (FDC) maintenance and organization of germinal centres. In follicular lymphoma, FDCs are often disarrayed and may lack antigens indicative of terminal differentiation. We investigated the in situ distribution of cells producing lymphotoxin-beta (LTB), lymphotoxin-alpha (LTA), and tumour necrosis factor-alpha (TNFA) transcripts in human reactive lymph nodes and in follicular lymphomas with follicular or diffuse growth pattern. LTB was the cytokine most abundantly produced in germinal centres...
April 2018: Journal of Pathology. Clinical Research
https://www.readbyqxmd.com/read/29665216/peak-visual-gamma-frequency-is-modified-across-the-healthy-menstrual-cycle
#13
Rachael L Sumner, Rebecca L McMilllan, Alexander D Shaw, Krish D Singh, Fred Sundram, Suresh D Muthukumaraswamy
Fluctuations in gonadal hormones over the course of the menstrual cycle are known to cause functional brain changes and are thought to modulate changes in the balance of cortical excitation and inhibition. Animal research has shown this occurs primarily via the major metabolite of progesterone, allopregnanolone, and its action as a positive allosteric modulator of the GABAA receptor. Our study used EEG to record gamma oscillations induced in the visual cortex using stationary and moving gratings. Recordings took place during twenty females' mid-luteal phase when progesterone and estradiol are highest, and early follicular phase when progesterone and estradiol are lowest...
April 17, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29664794/positive-surgical-margins-in-favorable-stage-differentiated-thyroid-cancer
#14
Catherine E Mercado, Peter A Drew, Christopher G Morris, Peter T Dziegielewski, William M Mendenhall, Robert J Amdur
OBJECTIVE: The significance of positive margin in favorable-stage well-differentiated thyroid cancer is controversial. We report outcomes of positive-margin patients with a matched-pair comparison to a negative-margin group. MATERIALS AND METHODS: A total of 25 patients with classic-histology papillary or follicular carcinoma, total thyroidectomy +/- node dissection, stage T1-3N0-1bM0, positive surgical margin at primary site, adjuvant radioactive iodine (I-131), and age older than 18 years were treated between 2003 and 2013...
April 16, 2018: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29664789/what-is-new-in-the-management-of-poor-ovarian-response-in-ivf
#15
Alberto Vaiarelli, Danilo Cimadomo, Nicolò Ubaldi, Laura Rienzi, Filippo Maria Ubaldi
PURPOSE OF REVIEW: The management and treatment of patients with poor ovarian response is still a controversial issue in IVF. Increasing evidences demonstrate that the number of oocytes retrieved after a controlled ovarian stimulation (COS) greatly influences the clinical outcome in terms of cumulative live birth per started cycle. For this reason, any COS should aim to optimize the number of oocytes according to the ovarian reserve of the patient. The aim of this review is to provide an overview of new strategies proposed to manage poor responders according to the novel POSEIDON classification...
April 16, 2018: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29664570/what-if-protective-immunity-is-antigen-driven-and-not-due-to-so-called-memory-b-and-t-cells
#16
REVIEW
Rolf M Zinkernagel
Vaccines or early childhood exposure to infection mediate immunity, that is, improved resistance against disease and death caused by a second infection with the same agent. This has been explained by and equaled to immunological memory, that is, an "altered immune system behavior" that is maintained in a presumably antigen-independent fashion. This review summarizes epidemiological and experimental data, that largely falsify this idea and that show that periodic re-exposure to antigen either, artificially as vaccines or naturally as low-level persisting antigens or infections, or immune complexes on follicular dendritic cells or endemic re-exposure is necessary for protection...
May 2018: Immunological Reviews
https://www.readbyqxmd.com/read/29664547/hsd3b2-hsd17b1-hsd17b2-esr1-esr2-and-ar-expression-in-infertile-women-with-endometriosis
#17
Maciej Osiński, Przemysław Wirstlein, Ewa Wender-Ożegowska, Mateusz Mikołajczyk, Paweł Piotr Jagodziński, Małgorzata Szczepańska
OBJECTIVES: The development of endometriosis is associated with changes in the expression of genes encoding the 3β-hydroxysteroid dehydrogenase type II (HSD3B2) and 17β-hydroxysteroid dehydrogenase type II (HSD17B2), estrogen receptors 1 (ESR1) and 2 (ESR2) and the androgen receptor (AR). However, little is known about the expression of HSD3B2, HSD17B1, HSD17B2, ESR1 ESR2 and AR during the endometrial phases in eutopic endometrium from infertile women with endometriosis. MATERIAL AND METHODS: Using RT-qPCR analysis, we assessed the expression of the studied genes in the follicular and luteal phases in eutopic endometrium from fertile women (n = 17) and infertile women (n = 35) with endometriosis...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29664020/accumulation-of-follicular-cd8-t-cells-in-pathogenic-siv-infection
#18
Sara Ferrando-Martinez, Eirini Moysi, Amarendra Pegu, Sarah Andrews, Krystelle Nganou Makamdop, David Ambrozak, Adrian B McDermott, David Palesch, Mirko Paiardini, George N Pavlakis, Jason M Brenchley, Daniel Douek, John R Mascola, Constantinos Petrovas, Richard A Koup
LN follicles constitute major reservoir sites for HIV/SIV persistence. Cure strategies could benefit from the characterization of CD8+ T cells able to access and eliminate HIV-infected cells from these areas. In this study, we provide a comprehensive analysis of the phenotype, frequency, localization, and functionality of follicular CD8+ T cells (fCD8+) in SIV-infected nonhuman primates. Although disorganization of follicles was a major factor, significant accumulation of fCD8+ cells during chronic SIV infection was also observed in intact follicles, but only in pathogenic SIV infection...
April 16, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29663591/research-progress-on-the-role-of-melatonin-and-its-receptors-in-animal-reproduction-a-comprehensive-review
#19
REVIEW
H S Talpur, I B Chandio, R D Brohi, T Worku, Z Rehman, D Bhattarai, F Ullah, L JiaJia, L Yang
Melatonin and its receptors play a crucial role in the regulation of the animal reproductive process, primarily in follicular development. However, the role that melatonin performs in regulating hormones related with reproduction remains unclear. Melatonin and its receptors are present both in female and male animals' organs, such as ovaries, heart, brain and liver. Melatonin regulates ovarian actions and is a key mediator of reproductive actions. Melatonin has numerous effects on animal reproduction, such as protection of gametes and embryos, response to clock genes, immune-neuroendocrine, reconciliation of seasonal variations in immune function, and silence or blockage of genes...
April 16, 2018: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/29663501/the-effect-of-plant-lectins-on-the-survival-and-malignant-behaviors-of-thyroid-cancer-cells
#20
Engin Kaptan, Serap Sancar-Bas, Aylin Sancakli, Suna Bektas, Sehnaz Bolkent
Altered or aberrant glycosylation is a common phenomenon in cancer cells and it originates from changes in the expression of the enzymes, glycosyltransferase, and glycosidase which up-regulate in response to some oncogenes in the glycan synthesis pathway. In this present study, it has been aimed to determine the alteration of sialic acid and fucose expressions in the cell surface of human thyroid carcinoma cells and investigate the changes in tumorigenic and malignant characters after treating them with specific plant lectins...
April 16, 2018: Journal of Cellular Biochemistry
keyword
keyword
25717
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"