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https://www.readbyqxmd.com/read/29149029/kappaphycus-alvarezii-as-a-food-supplement-prevents-diet-induced-metabolic-syndrome-in-rats
#1
Stephen Wanyonyi, Ryan du Preez, Lindsay Brown, Nicholas A Paul, Sunil K Panchal
The red seaweed, Kappaphycus alvarezii, was evaluated for its potential to prevent signs of metabolic syndrome through use as a whole food supplement. Major biochemical components of dried Kappaphycus are carrageenan (soluble fiber ~34.6%) and salt (predominantly potassium (K) 20%) with a low overall energy content for whole seaweed. Eight to nine week old male Wistar rats were randomly divided into three groups and fed for 8 weeks on a corn starch diet, a high-carbohydrate, high-fat (H) diet, alone or supplemented with a 5% (w/w) dried and milled Kappaphycus blended into the base diet...
November 17, 2017: Nutrients
https://www.readbyqxmd.com/read/29146986/cascading-predator-effects-in-a-fijian-coral-reef-ecosystem
#2
Douglas B Rasher, Andrew S Hoey, Mark E Hay
Coral reefs are among Earth's best-studied ecosystems, yet the degree to which large predators influence the ecology of coral reefs remains an open and contentious question. Recent studies indicate the consumptive effects of large reef predators are too diffuse to elicit trophic cascades. Here, we provide evidence that such predators can produce non-consumptive (fear) effects that flow through herbivores to shape the distribution of seaweed on a coral reef. This trophic cascade emerged because reef topography, tidal oscillations, and shark hunting behaviour interact to create predictable "hot spots" of fear on the reef where herbivores withhold feeding and seaweeds gain a spatial refuge...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29146256/isolation-purification-structural-elucidation-and-antimicrobial-activities-of-kocumarin-a-novel-antibiotic-isolated-from-actinobacterium-kocuria-marina-cmg-s2-associated-with-the-brown-seaweed-pelvetia-canaliculata
#3
Bushra Uzair, Farid Menaa, Barkat Ali Khan, Faryal Vali Mohammad, Viqar Uddin Ahmad, Ryad Djeribi, Bouzid Menaa
AIMS: Screening of seaweed-associated bacteria capable of producing antimicrobials. METHODS AND RESULTS: Fifteen microbial strains, associated to the brown seaweed Pelvetia canaliculata (Linnaeus) attached to the rocks of Sonmiani Beach (Karachi, Pakistan), were screened. Crude extract filtrates of CMG S2 strain grew on Zobell marine agar (ZMA) had the most remarkable antimicrobial activity. Based on its phenotypic aspects (e.g. Gram-positive, microccoid form), biochemical characteristics (e...
January 2018: Microbiological Research
https://www.readbyqxmd.com/read/29142150/effect-of-maternal-supplementation-with-seaweed-powder-on-immune-status-of-liver-and-lymphoid-organs-of-piglets
#4
Ahmad Farid Nikmal Azizi, Ryoko Miyazaki, Takeru Yumito, Yuki Ohashi, Susumu Uno, Umi Miyajima, Mayu Kumamoto, Shinji Uchiyama, Masahiro Yasuda
This study was performed to evaluate the effect of maternal supplementation with seaweed powder (SWP) on the immune status of piglets. Sows were supplementary fed SWP from 85-days of gestation until delactation. Forty-days old piglets were euthanized and lymphocyte subsets were analyzed. The results showed a significantly higher relative population of CD4(+)CD8(+) T cells in the thymus, lymph node, tonsil (P<0.05), peripheral blood mononuclear cells, spleen and liver (P<0.01) of piglets derived from treated sows...
November 14, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29141543/effects-of-fucoidan-and-chemotherapeutic-agent-combinations-on-malignant-and-non-malignant-breast-cell-lines
#5
Aisha Abudabbus, Jelili A Badmus, Salem Shalaweh, Rolene Bauer, Donavon Hiss
OBJECTIVES: Breast cancer is a leading cause of death among women in both developed and Third World countries. Fucoidan is a natural plant product produced by brown seaweeds with proven anticancer potential. This study determined the cytotoxic, apoptotic and cell cycle effects of fucoidan alone and in combination with first-line anticancer drugs (cisplatin, doxorubicin and taxol) in MCF-7 breast cancer cells and non-malignant MCF-12A breast epithelial cells as control. METHODS: Cytotoxicity was evaluated using the MTT reduction assay...
November 14, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29140261/proximate-composition-and-nutritional-value-of-three-macroalgae-ascophyllum-nodosum-fucus-vesiculosus-and-bifurcaria-bifurcata
#6
José M Lorenzo, Rubén Agregán, Paulo E S Munekata, Daniel Franco, Javier Carballo, Selin Şahin, Ramón Lacomba, Francisco J Barba
Proximate composition (moisture, protein, lipid and ash content) and nutritional value (fatty acid, amino acid and mineral profile) of three macroalgae (Ascophyllum nodosum, Fucus vesiculosus and Bifurcaria bifurcate) were studied. Chemical composition was significantly (p < 0.001) different among the three seaweeds. In this regard, the B. bifurcata presented the highest fat content (6.54% of dry matter); whereas, F. vesiculosus showed the highest protein level (12.99% dry matter). Regarding fatty acid content, the polyunsaturated fatty acids (PUFAs) were the most abundant followed by saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs)...
November 15, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29138822/fucoidan-inhibits-ca2-responses-induced-by-a-wide-spectrum-of-agonists-for-g%C3%A2-protein%C3%A2-coupled-receptors
#7
Hong Wu, Shuibo Gao, Min Fu, Takashi Sakurai, Susumu Terakawa
Fucoidan, a sulfated polysaccharide extracted from brown seaweed, has been used in traditional Chinese herbal medicine to treat thyroid tumors for many years. Although a number of its cellular effects have been investigated, the role of fucoidan in molecular signaling, particularly in Ca2+ signaling, remains largely unknown. In the present study, the effects of fucoidan on Ca2+ responses in HeLa cells, human umbilical vein endothelial cells and astrocytes were investigated using a wide range of receptor agonists...
November 13, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29138816/protective-effects-of-fucoidan-against-hyperoxic-lung-injury-via-the-erk-signaling-pathway
#8
Minghao Nie, Yan Wang, Yanhong Lu, Ying Yuan, Yingying Liu, Xiurong Li
High oxygen mechanical ventilation is widely used to treat various lung diseases; however, it may result in hyperoxia, which induces inflammation and lung injury. Fucoidan is an extract of the seaweed Fucus vesiculosus, which has previously been reported to exert effects against diabetic nephropathy. The present study is the first, to the best of our knowledge, to investigate the protective effects of fucoidan against hyperoxic lung injury. Balb/c mice were ventilated with 100% oxygen, with or without the atomization inhalation of fucoidan, for 36 h...
November 10, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29137997/alginic-acid-a-mild-and-renewable-bifunctional-heterogeneous-biopolymeric-organocatalyst-for-efficient-and-facile-synthesis-of-polyhydroquinolines
#9
Mohammad G Dekamin, Zahra Karimi, Zahra Latifidoost, Siamand Ilkhanizadeh, Hamed Daemi, M Reza Naimi-Jamal, Mehdi Barikani
Alginic acid, a widely used naturally occurring carbohydrate which is generally derived from brown seaweeds, can be considered as a bifunctional heterogeneous and green biopolymeric organocatalyst. Alginic acid, without any post-modification with active Bronsted or Lewis acid centers, was found to be a highly active, cost-effective, commercially-available, renewable and recoverable heterogeneous biopolymeric organocatalyst for the expeditious synthesis of polyhydroquinolines (PHQs). Polyhydroquinolines were synthesized from the four-component Hantzsch reaction of ethyl acetoacetate, different aldehydes, ammonium acetate and cyclic 1,3-diones under mild conditions in high to quantitative yields, 75-97%, using alginic acid...
November 11, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29134619/complete-acid-based-hydrolysis-assay-for-carbohydrate-quantification-in-seaweed-a-species-specific-optimized-approach
#10
Emily T Kostas, Stuart J Wilkinson, Daniel A White, David J Cook
Accurate quantification of the carbohydrate content of biomass is crucial for many bio-refining processes. The most commonly followed protocol is typically a modification of the NREL-based assay (specifically designed for carbohydrate analysis from lignocellulosic biomass). However, this NREL protocol was revealed to be excessively thermochemically harsh for seaweed biomass. This can result in erroneously low total sugar quantification as the reaction severity can degrade a proportion of the liberated sugars to decomposition products such as furans...
November 14, 2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29130494/variability-of-iodine-in-temperate-seaweeds-and-iodine-accumulation-kinetics-of-fucus-vesiculosus-and-laminaria-digitata-phaeophyceae-ochrophyta
#11
Udo Nitschke, Philip Walsh, Jade McDaid, Dagmar B Stengel
The biogeochemistry of iodine in temperate coastal ecosystems is largely mediated by macroalgae, which act as a major biological sink and source of iodine. Their capacity to accumulate, retain and release iodine has been associated with abiotic and biotic stressors, but quantitative information is limited. We evaluated the seasonal iodine retention capacity of eleven macroalgal species belonging to different systematic groups, collected from two sites in Ireland. Iodine accumulation and retention were then further quantified in Fucus vesiculosus and Laminaria digitata in relation to I(-) concentrations in seawater and temperature...
November 12, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/29125578/an-insight-into-sargassum-muticum-cytoprotective-mechanisms-against-oxidative-stress-on-a-human-cell-in-vitro-model
#12
Susete Pinteus, Marco F L Lemos, Joana Silva, Celso Alves, Agnieszka Neugebauer, Rafaela Freitas, Adriana Duarte, Rui Pedrosa
Sargassum muticum is a brown seaweed with strong potential to be used as a functional food ingredient, mainly due to its antioxidant properties. It is widely used in traditional oriental medicine for the treatment of numerous diseases. Nevertheless, few studies have been conducted to add scientific evidence on its effects as well as on the mechanisms of action involved. In this work, the human cell line MCF-7 was used as an in vitro cellular model to evaluate the capability of Sargassum muticum enriched fractions to protect cells on an oxidative stress condition...
November 10, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29117751/phenotypic-and-mtdna-variation-in-philippine-kappaphycus-cottonii-gigartinales-rhodophyta
#13
Richard V Dumilag, William George M Gallardo, Christian Philip C Garcia, YeaEun You, Alyssa Keren G Chaves, Lance Agahan
Members of the carrageenan-producing seaweeds of the genus Kappapphycus have a complicated taxonomic history particularly with regard to species identification. Many taxonomic challenges in this group have been currently addressed with the use of mtDNA sequences. The phylogenetic status and genetic diversity of one of the lesser known species, Kappaphycus cottonii, have repeatedly come into question. This study explored the genetic variation in Philippine K. cottonii using the mtDNA COI-5P gene and cox2-3 spacer sequences...
November 9, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/29115386/protein-extracted-from-porphyra-yezoensis-prevents-cisplatin-induced-nephrotoxicity-by-downregulating-the-mapk-and-nf-%C3%AE%C2%BAb-pathways
#14
In-Hye Kim, Mi-Jin Kwon, Jae-Hun Jung, Taek-Jeong Nam
Acute renal failure is a serious complication of treatment with the anticancer drug cisplatin. Cisplatin exerts a cytotoxic effect on renal cells by inducing apoptosis through activating the tumor suppressor p53, nuclear factor‑κB (NF‑κB) and mitogen‑activated protein kinase (MAPK)/p38 pathways. Effects of protein extracts of the brown seaweed Porphyra yezoensis (P. yezoensis) on cytotoxicity, inflammation and cell proliferation have been reported; however, the effects of P. yezoensis protein (PYP) extract on cisplatin‑induced renal injury have remained elusive...
October 26, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29113895/isolation-structural-characterization-and-antiproliferative-activity-of-phycocolloids-from-the-red-seaweed-laurencia-papillosa-on-mcf-7-human-breast-cancer-cells
#15
Ahmed Ghannam, Hossam Murad, Marie Jazzara, Adnan Odeh, Abdul Wahab Allaf
Hydrocolloids from seaweeds (phycocolloids) have interesting functional properties like antiproliferative activity. Marine algae consumptions are linked to law cancer incidences in countries that traditionally consume marine products. In this study, we have investigated water-soluble sulfated polysaccharides isolated from the red seaweed Laurencia papillosa and determined their chemical characteristics and biological activities on the human breast cancer cell line MCF-7. Total polysaccharides were extracted and fractionated from L...
November 4, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29110623/a-review-of-the-components-of-seaweeds-as-potential-candidates-in-cancer-therapy
#16
Ban-Feng Ruan, Wei-Wei Ge, Meng-Xue Lin, Qing-Shan Li
The marine natural products (MNPs) isolated from seaweeds-associated microbial communities have been caused a substantial part of attention owing to their exceptional nutritional and pharmacology application, such as antiviral, anticancer, antiprotozoal, antifungal, and antibacterial properties and so on. Particularly, there are several MNPs have been displayed attractive value for developing novel anticancer agents for clinical application. This review covers the literature published in the recent 5 years for the isolation and identification of novel anticancer MNPs from seaweeds...
November 6, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/29108108/antibacterial-aryl-crowned-polyketide-from-bacillus-subtilis-associated-with-seaweed-anthophycus-longifolius
#17
Kajal Chakraborty, Bini Thilakan, Vinaya Kizhakkepatt Kizhakkekalam
AIMS: Microbiological, biotechnological and chemical characterization of a previously undescribed aryl-crowned polyketide from Bacillus subtilis MTCC 10403 isolated from brown seaweed Anthophycus longifolius with activity against opportunistic Gram-negative food-borne pathogenic bacterial strains. METHODS AND RESULTS: A culture-dependent method was used to isolate heterotrophic B. subtilis associated with A. longifolius, and assessed for its antimicrobial properties...
November 6, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29107095/anticancer-activity-of-seaweeds
#18
REVIEW
Anllely G Gutiérrez-Rodríguez, Claudia Juárez-Portilla, Tatiana Olivares-Bañuelos, Rossana C Zepeda
Cancer is a major health problem worldwide and still lacks fully effective treatments. Therefore, alternative therapies, using natural products, have been proposed. Marine algae are an important component of the marine environment, with high biodiversity, and contain a huge number of functional compounds, including terpenes, polyphenols, phlorotannins, and polysaccharides, among others. These compounds have complex structures that have shown several biological activities, including anticancer activity, in several in vitro and in vivo models...
October 26, 2017: Drug Discovery Today
https://www.readbyqxmd.com/read/29104249/carrageenans-sulfated-polysaccharides-from-red-seaweeds-as-matrices-for-the-inclusion-of-echinochrome
#19
Irina M Yermak, Natalia P Mischchenko, Viktoria N Davydova, Valery P Glazunov, Daria V Tarbeeva, Anna O Kravchenko, Evgeniya A Pimenova, Irina V Sorokina
The possibility of using different types of carrageenans (CRG) as matrixes for incorporating of echinochrome A (Ech) was investigated. Ech interacts with carrageenans and is incorporated into the macromolecular structure of the polysaccharide. The inclusion of Ech in carrageenan matrices decreased its oxidative degradation and improved its solubility. The changing in the charge and morphology of CRGs during binding with Ech was observed. The rate of Ech release from CRG matrices depended on the structure of the used polysaccharide and the presence of specific ions...
November 1, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29103523/structural-features-and-water-sorption-isotherms-of-carrageenans-a-prediction-model-for-hybrid-carrageenans
#20
María D Torres, Francisco Chenlo, Ramón Moreira
water adsorption and desorption isotherms of kappa/iota-hybrid carrageenan (KIC) extracted from Mastocarpus stellatus red seaweed as well as commercial kappa-carrageenan (KC) and iota-carrageenan (IC) were obtained at several temperatures (5, 25, 45, 65°C). Spectroscopic and X-ray diffraction techniques allowed identifying the fundamental composition of above biopolymers. Crystallinity values (%) followed the order IC (25.4±0.6)> KIC (9.3±0.4)> KC (4.8±0.2), which nicely matched with the hygroscopic properties of the tested biopolymers (KC > KIC > IC) at each temperature...
January 15, 2018: Carbohydrate Polymers
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