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https://www.readbyqxmd.com/read/29057527/exploring-the-genomic-basis-of-early-childhood-caries-a-pilot-study
#1
Jami L Ballantine, Jenna C Carlson, Andrea G Ferreira Zandoná, Cary Agler, Leslie P Zeldin, Richard Gary Rozier, Michael W Roberts, Patricia V Basta, Jason Luo, Mikafui E Antonio-Obese, Daniel W McNeil, Robert J Weyant, Richard J Crout, Rebecca L Slayton, Steven M Levy, John R Shaffer, Mary L Marazita, Kari E North, Kimon Divaris
OBJECTIVE: A genetic component in early childhood caries (ECC) is theorized, but no genome-wide investigations of ECC have been conducted. This pilot study is part of a long-term research program aimed to: (1) determine the proportion of ECC variance attributable to the human genome and (2) identify ECC-associated genetic loci. METHODS: The study's community-based sample comprised 212 children (mean age=39 months; range = 30-52 months; males = 55%; Hispanic/Latino = 35%, African-American = 32%; American Academy of Pediatric Dentistry definition of ECC prevalence = 38%)...
October 23, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/29057381/association-of-sleep-duration-symptoms-and-disorders-with-mortality-in-adults-with-chronic-kidney-disease
#2
Ana C Ricardo, Vivien Goh, Jinsong Chen, Esteban Cedillo-Couvert, Mary Kapella, Bharati Prasad, Sharmila Parvathaneni, Kristen Knutson, James P Lash
INTRODUCTION: In general populations, short and long sleep duration, poor sleep quality and sleep disorders have been associated with increased risk of death. We evaluated these associations in individuals with chronic kidney disease (CKD). METHODS: Prospective cohort study of 1,452 National Health and Nutrition Examination Survey (NHANES) 2005-2008 participants with CKD. CKD was defined by estimated glomerular filtration rate <60 ml/min/1.73m(2) or urine albumin-to-creatinine ratio ≥30 mg/g...
September 2017: KI Reports
https://www.readbyqxmd.com/read/29056842/forecasting-disparities-with-early-substance-use-milestones
#3
Megan E Roberts, Nichea S Spillane, Suzanne M Colby, Kristina M Jackson
Substance use contributes to health disparities across race/ethnicity, gender, and socioeconomic status (SES). Although adolescent research indicates group-based differences in regular use, few studies have examined patterns when initiation is just beginning. Using a sample of 917 Rhode Island middle schools students (54% female, 26% non-Hispanic White), we collected demographic information at baseline (M age 12.2); we then examined ever-puff (cigarettes), ever-sip (alcohol), and ever-use (marijuana) behaviors three years later...
2017: Journal of Child & Adolescent Substance Abuse
https://www.readbyqxmd.com/read/29056437/texting-to-increase-contraceptive-initiation-among-adolescents-in-the-emergency-department
#4
Lauren S Chernick, Melissa S Stockwell, Mengfei Wu, Paula M Castaño, Rebecca Schnall, Carolyn L Westhoff, John Santelli, Peter S Dayan
PURPOSE: To evaluate the feasibility and acceptability of a text messaging intervention to increase contraception among adolescent emergency department patients. METHODS: A pilot randomized controlled trial of sexually active females aged 14-19 receiving 3 months of theory-based, unidirectional educational and motivational texts providing reproductive health information versus standardized discharge instructions. Blinded assessors measured contraception initiation via telephone follow-up and health record review at 3 months...
October 19, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29056310/breastfeeding-outcomes-in-washington-state-determining-the-effect-of-loving-support-peer-counseling-program-and-characteristics-of-participants-at-wic-agencies
#5
Catherine Hui Min Lee, Jean O'Leary, Phyllis Kirk, Timothy A Lower
OBJECTIVE: Determining the effect of the Loving Support Peer Counseling Program (LSPCP), and characteristics of participants on breastfeeding (BF) outcomes at Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) agencies in Washington State. DESIGN: Nonrandomized treatment vs control. SETTING: Public Health-Seattle and King County (PHSKC), Catholic Health Initiatives Franciscan Medical Group (CHIFMG). PARTICIPANTS: Women enrolled in WIC (intervention: PHSKC, n = 15,290; CHIFMG, n = 3,582)...
October 19, 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/29056309/sensitive-timing-for-risk-of-overweight-among-infants-of-low-income-hispanic-immigrants
#6
Kathleen F Gaffney, Albert V Brito, Deborah A Kermer, Panagiota Kitsantas
INTRODUCTION: This study examined the association between early weight gain (0-6 months) and risk for overweight, as defined by the Institute of Medicine, at 1 year among infants of low-income Hispanic immigrant mothers. METHOD: Weight-for-age data were extracted from electronic medical records of 335 infants with gestations of 37 weeks or longer and birthweights appropriate for gestational age and without medical problems likely to interfere with growth or feeding...
October 19, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/29056283/fat-mass-to-fat-free-mass-ratio-reference-values-from-nhanes-iii-using-bioelectrical-impedance-analysis
#7
J Xiao, S A Purcell, C M Prado, M C Gonzalez
BACKGROUND & AIM: Low fat-free mass (FFM) or high fat mass (FM) are abnormal body composition phenotypes associated with morbidity. These conditions in combination lead to worse health outcomes, and can be identified by a high FM/FFM ratio. Here, we developed sex, age, and body mass index (BMI) stratified, population-based FM/FFM reference values using bioelectrical impedance analysis (BIA) measurements. METHODS: White, non-Hispanic individuals aged 18-90 years old with data for weight, stature and BIA resistance measures from the third National Health and Nutrition Examination Survey (NHANES) III were included...
October 6, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29056175/examining-racial-and-ethnic-differences-in-nursing-home-quality
#8
Jennifer Gaudet Hefele, Grant A Ritter, Christine E Bishop, Andrea Acevedo, Candi Ramos, Laurie A Nsiah-Jefferson, Gabrielle Katz
BACKGROUND: Identifying racial/ethnic differences in quality is central to identifying, monitoring, and reducing disparities. Although disparities across all individual nursing home residents and disparities associated with between-nursing home differences have been established, little is known about the degree to which quality of care varies by race//ethnicity within nursing homes. A study was conducted to measure within-facility differences for a range of publicly reported nursing home quality measures...
November 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29055919/the-expression-of-pnpla3-polymorphism-could-be-the-key-for-severe-liver-disease-in-nafld-in-hispanic-population
#9
Leonardo A Martínez, Elena Larrieta, David Kershenobich, Aldo Torre
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) encompasses: fatty liver (SS), steatohepatitis (NASH) with or without fibrosis and cirrhosis. Patatine-like phosphatas in domain 3 (PNPLA3; adiponutrin; SNP rs738409 C/G, M148I) shows anabolic and catabolic activities on lipid metabolism and significant association to fatty liver content; however, I148M demographics and ethnics, as its role with NAFLD have not been fully elucidated. MATERIAL AND METHODS: PNPLA3 genotyping from peripheral blood DNA by polymerase chain reaction (PCR) and direct sequencing, 211 patients diagnosed with NAFLD including SS, NASH and fibrosis spectrum...
October 16, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29055217/trends-in-and-factors-affecting-the-observed-levels-of-urinary-inorganic-and-total-blood-mercury-among-us-children-adolescents-adults-and-senior-citizens-over-2005-2012
#10
Ram B Jain
Data from National Health and Nutrition Examination Survey (NHANES) for 2005-2012 were used to (i) study adjusted and unadjusted trends in the levels of urinary inorganic mercury (UIHG) and total blood mercury (TBHG) and (ii) factors that affect the observed levels of UIHG and TBHG among children aged 1-5 (CHLD15) and 6-11 (CHLD611) years, adolescents aged 12-19 years (ADOL), adults aged 20-64 years (ADLT), and senior citizens aged >=65 years (SNR). Decrease in adjusted levels of UIHG for each 2-year NHANES cycle for CHLD611 was 0...
September 6, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29054978/breast-cancer-in-latinas-a-focus-on-intrinsic-subtypes-distribution
#11
Silvia J Serrano-Gómez, Laura Fejerman, Jovanny Zabaleta
Breast cancer is the most frequent cancer in women worldwide. It is classified into intrinsic subtypes characterized by different molecular profiles and prognosis. The prevalence of the different intrinsic subtypes varies between population groups. Immunohistochemistry surrogates based on the expression of the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) have been widely used to study the distribution of intrinsic subtypes in Non-Hispanic Whites and African Americans, but data is limited for Hispanic/Latina women...
October 20, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29054604/susceptibility-loci-associated-cutaneous-squamous-cell-carcinoma-invasiveness
#12
Wei Wang, Eric Jorgenson, Alice S Whittemore, Maryam M Asgari
Genome-wide association studies (GWAS) have identified genetic loci associated with cutaneous squamous cell carcinoma (cSCC) risk, but single nucleotide polymorphisms (SNP) associations with cSCC invasiveness have not been investigated. We examined associations between cSCC invasiveness and 23 reported SNPs among 67,833 non-Hispanic white subjects. Additionally, we performed a genome-wide scan and identified one SNP with significantly different frequencies in 5,724 subjects with at least one invasive tumor and 1,943 subjects with in-situ tumors only...
October 17, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29054243/hiv-testing-at-visits-to-physicians-offices-in-the-u-s-2009-2012
#13
D Cal Ham, Shirley Lecher, Roman Gvetadze, Ya-Lin A Huang, Philip Peters, Karen W Hoover
INTRODUCTION: HIV testing serves as an entry point for HIV care services for those who test HIV positive, and prevention services for those who test HIV negative. The Centers for Disease Control and Prevention recommends routine testing of adults and adolescents in healthcare settings. To identify missed opportunities for HIV testing at U.S. physicians' offices, data from the National Ambulatory Care Surveys from 2009 to 2012 were analyzed. METHODS: The mean annual number and percentage of visits with an HIV test among HIV-uninfected nonpregnant females and males aged 15-65 years was estimated using weighted survey data...
November 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29054031/mental-health-of-heroin-users-with-differing-injection-drug-use-histories-a-non-treatment-sample-of-mexican-american-young-adult-men
#14
Kathryn M Nowotny, Tasha Perdue, Alice Cepeda, Avelardo Valdez
BACKGROUND: While the comorbidity of mental health and injecting heroin has been documented, current research is limited by describing the mental health of people who inject drugs without a comparison group and by the lack of research on nontreatment samples in the United States, particularly among Hispanics. The purpose of this study was to examine the association of injecting history (never, former, occasional, and daily) and multiple outcomes of global and mental health using a sample of U...
October 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29053944/investigation-of-the-3-epi-25-oh-d3-of-25-hydroxyvitamin-d3-in-urban-schoolchildren
#15
Samantha E Berger, Maria I Van Rompay, Catherine M Gordon, Elizabeth Goodman, Misha Eliasziw, Michael F Holick, Jennifer M Sacheck
BACKGROUND: The physiological relevance C-3 epimer of 25-hydroxyvitamin D [3-epi-25(OH)D] is not well understood among youth. OBJECTIVE: To assess whether demographic/physiologic characteristics were associated with 3-epi-25(OH)D3 concentrations in youth. METHODS: Associations between 3-epi-25(OH)D3 and demographics, 3-epi-25(OH)D3, total 25-hydroxyvitamin (25(OH)D) (25(OH)D2 + 25(OH)D3), total cholesterol, HDL, LDL and triglycerides were examined in racially/ethnically diverse schoolchildren (n=682, 8-15yrs) at Boston-area urban schools...
October 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29053393/depression-and-alcohol-use-in-a-national-sample-of-hispanic-adolescents
#16
Ashley L Merianos, Christopher M Swoboda, Oladunni A Oluwoye, Tamika D Gilreath, Jennifer B Unger
BACKGROUND: Underage alcohol use and depression remain public health concerns for Hispanic adolescents nationwide. OBJECTIVES: The study purpose was to identify the profiles of depression among Hispanic adolescents who reported experiencing depressive symptoms in their lifetime and classify them into groups based on their symptoms. Based on classifications, we examined the relationship between past year alcohol use and severity of depressive symptoms while controlling for sex and age...
October 20, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29053377/substance-use-among-bi-multiracial-youth-in-the-united-states-profiles-of-psychosocial-risk-and-protection
#17
Trenette Clark Goings, Christopher P Salas-Wright, Matthew O Howard, Michael G Vaughn
BACKGROUND: Bi/multiracial youth face higher risk of engaging in substance use than most monoracial youth. OBJECTIVES: This study contrasts the prevalence of substance use among bi/multiracial youth with that of youth from other racial/ethnic groups, and identifies distinct profiles of bi/multiracial youth by examining their substance use risk. METHODS: Using data from the National Survey on Drug Use and Health (collected between 2002 and 2014), we analyze data for 9,339 bi/multiracial youth ages 12-17 living in the United States...
October 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29052224/opiate-prescribing-in-hospitalized-older-adults-patterns-and-outcomes
#18
Sutapa Maiti, Liron Sinvani, Michele Pisano, Andrzej Kozikowski, Vidhi Patel, Meredith Akerman, Karishma Patel, Christopher Smilios, Christian Nouryan, Guang Qiu, Renee Pekmezaris, Gisele Wolf-Klein
BACKGROUND/OBJECTIVES: Whereas opiate prescribing patterns have been well described in outpatient and emergency department settings, they have been less defined in hospitalized older adults. The objective was to describe patterns of opiate prescribing and associated outcomes in hospitalized older adults. DESIGN: Retrospective cohort study. SETTING: Tertiary care facility. PARTICIPANTS: Hospitalized medical patients aged 65 and older (N = 9,245; mean age 80...
October 20, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29052175/african-americans-with-cirrhosis-are-less-likely-to-receive-endoscopic-variceal-screening-within-one-year-of-cirrhosis-diagnosis
#19
Ann Robinson, Hesam Tavakoli, Benny Liu, Taft Bhuket, Ramsey Cheung, Robert J Wong
BACKGROUND: Esophageal variceal hemorrhage is a complication of cirrhosis that carries high mortality, and can be reduced with timely endoscopic variceal screening and treatment. AIM: We aim to evaluate overall rates of and disparities in receipt of endoscopic variceal screening among an ethnically diverse urban safety-net hospital. METHODS: All consecutive adults with cirrhosis (7/1/2014 to 12/31/2015) were retrospectively evaluated to determine the rates of receiving esophageal variceal screening within 6 months and within 1 year after cirrhosis diagnosis...
October 19, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29051341/indoor-tanning-dependence-in-young-adult-women
#20
Darren Mays, Michael B Atkins, Jaeil Ahn, Kenneth P Tercyak
Background: There is mounting evidence that young people can develop a dependence on indoor tanning, but research on factors associated with indoor tanning dependence remains limited.Methods: This cross-sectional study investigated factors associated with indoor tanning dependence in a community sample of 389 non-Hispanic white young adult women ages 18 to 30 who had indoor tanned ≥1 time in the past year. Participants completed measures of indoor tanning dependence, including the modified CAGE and modified Diagnostic and Statistical Manual for Mental Disorders-IV psychiatric screening assessments, indoor tanning behavior and beliefs, and behavioral and psychiatric comorbidity...
October 19, 2017: Cancer Epidemiology, Biomarkers & Prevention
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