Read by QxMD icon Read

Profile keratitis

David T Truong, Minh-Thuy Bui, H Dwight Cavanagh
PURPOSE: To review the epidemiology, risk factors, microbiologic spectrum, and treatment of microbial keratitis during a 5-year period at an urban public hospital in comparison with an adjacent private university practice. METHODS: Retrospective chart review in the 5-year interval, 2009 through 2014. Primary outcome measures included patient age at presentation, best-corrected visual acuity (BCVA), risk factors, culture and sensitivities, treatment, and complication occurrence...
October 7, 2016: Eye & Contact Lens
G K P Cruz, S B da Silva, I C de Azevedo, D P S R P Carvalho, P F Meireles, M A F Júnior, A F Vitor
BACKGROUND: The purpose of the study was to characterize the epidemiological profile and average time on the waiting list of patients undergoing an urgent corneal transplantation (CT) in a referral center in the state of Rio Grande do Norte, northeastern Brazil. METHODS: This cross-sectional study included cases of urgent corneal transplants performed in a referral center from January 2010 to December 2014. Data were collected between January and March 2015. RESULTS: Seventy-four cases of emergency CT were analyzed...
September 2016: Transplantation Proceedings
I-Huang Lin, Yi-Sheng Chang, Sung-Huei Tseng, Yi-Hsun Huang
Infectious keratitis after penetrating keratoplasty (PK) is a devastating condition that may result in graft failure and poor visual outcome. In this study, we retrospectively reviewed the medical records of patients who underwent PK between 2009 and 2014, and recorded those who developed infectious keratitis. We compared the predisposing factors and organisms isolated to those identified in our previous study, conducted between 1989 and 1994. The incidence of post-PK infectious keratitis decreased from 11...
September 2, 2016: Scientific Reports
Carla Sofia Ferreira, Luis Figueira, Nuno Moreira-Gonçalves, Raúl Moreira, Luis Torrão, Fernando Falcão-Reis
OBJECTIVES: To study the microbial profile, antibiotic susceptibility pattern, risk factors, therapeutic trends, and clinical outcomes for microbial keratitis (MK) in a tertiary health care center. METHODS: All cases with suspected bacterial keratitis that were followed at consultation from September 2007 to August 2015 were included. Microbial cultures were obtained and patients were managed following an internal protocol. RESULTS: Two hundred thirty-five patients were included, with a mean age of 50...
July 12, 2016: Eye & Contact Lens
Harshal Shrikant Rathi, Anitha Venugopal, Ramakrishnan Rengappa, Meenakshi Ravindran
PURPOSE: To determine the clinical profile and prognosis of Scedosporium keratitis. METHODS: All culture-proven cases were retrospectively analyzed for demographics, clinical characteristics, treatment offered, and resolution time with sequel. RESULTS: Among the 1792 culture-proven fungal keratitis cases in the study period, 10 (0.6%) were the result of Scedosporium. The mean age of patients was 44.2 years. Eight patients were male. A history of trauma was present in 8 patients...
August 17, 2016: Cornea
Aradhana Masih, Pradeep K Singh, Shallu Kathuria, Kshitij Agarwal, Jacques F Meis, Anuradha Chowdhary
Aspergillus species cause a wide spectrum of clinical infections. Although Aspergillus fumigatus and Aspergillus flavus remain the most commonly isolated species in aspergillosis, in the last decade, rare and cryptic Aspergillus species have emerged in diverse clinical settings. The present study analyzed the distribution and in vitro antifungal susceptibility profiles of rare Aspergillus species in clinical samples from patients with suspected aspergillosis in 8 medical centers in India. Further, a matrix-assisted laser desorption ionization-time of flight mass spectrometry in-house database was developed to identify these clinically relevant Aspergillus species...
September 2016: Journal of Clinical Microbiology
Ashok Kumar Reddy, Rangaiahgari Ashok, Madhavi Majety, Megharaj Chitta, Nitesh Narayen
Fungal keratitis due to Schizophyllum commune is very rare. In this study, we report the clinical and microbiological profile of five patients with fungal keratitis due to S. commune. Direct microscopic examination of corneal scrapings from all five patients showed septate branching hyaline fungal filaments. Similarly, in all five patients Sabouraud dextrose agar (SDA) plates inoculated with corneal scrapings showed white, cottony colonies on the second day of incubation. Lactophenol cotton blue stained wet preparation of 7-day-old colonies on SDA revealed clamp connections and no spores...
July 12, 2016: Mycoses
E Schaftenaar, R P H Peters, G S Baarsma, C Meenken, N S Khosa, S Getu, J A McIntyre, A D M E Osterhaus, G M G M Verjans
The purpose of this investigation was to determine the clinical and corneal microbial profile of infectious keratitis in a high human immunodeficiency virus (HIV) prevalence setting in rural South Africa. Data in this cross-sectional study were collected from patients presenting with symptoms of infectious keratitis (n = 46) at the ophthalmology outpatient department of three hospitals in rural South Africa. Corneal swabs were tested for herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), varicella zoster virus (VZV) and adenovirus DNA by real-time polymerase chain reaction (PCR) and for bacteria and fungi by culture...
September 2016: European Journal of Clinical Microbiology & Infectious Diseases
Emilie Courrier, Thierry Lépine, Guillaume Hor, Corinne Fournier, Zhiguo He, Mehdi Chikh, Caroline Urrea, Fahran-Falgi Al Anazi, Gilles Thuret, Philippe Gain
PURPOSE: To evaluate the size distribution of epithelial lesions of superficial punctate keratitis (SPK) in dry eye after staining of the ocular surface by sodium fluorescein. METHODS: Fluorescein was instilled in 10 patients with dry eye graded using the Oxford Scheme. Pictures were taken using a standard Topcon slit lamp with cobalt blue light, without barrier filter. Two magnifications (×10 and ×16) were used and calibrated using a certified standard reference grating, allowing the diameter of the observed objects to be determined with ImageJ software...
July 2016: Cornea
Huda S Al-Dhaheri, Mashael D Al-Tamimi, Rajiv B Khandekar, Mohammed Khan, Donald U Stone
BACKGROUND: To investigate prevalence and in vitro susceptibility trends of bacteria isolated from patients with bacterial keratitis from 2011 to 2014 in a tertiary care eye hospital in Saudi Arabia. METHODS: Retrospective review of bacterial isolates from corneal scraping of eyes with microbial keratitis. The most common isolates and their antibiotic resistance profiles were identified; trend analysis was performed over the study period. RESULTS: A total of 2037 bacterial isolates met inclusion criteria during the study period...
June 2016: Cornea
Gelareh S Noureddin, Sachiko Sasaki, Andrea L Butler, Peter Tilley, Diane Roscoe, Christopher J Lyons, Simon P Holland, Sonia N Yeung
OBJECTIVE: To report the clinical and microbiological profiles of paediatric patients with infectious keratitis in Vancouver, Canada. DESIGN: In this observational case series, the microbiology results and medical records of 17 eyes with microbial keratitis in 16 children aged 17 years or younger were retrospectively reviewed. These patients had undergone corneal scraping between May 2006 and April 2011 at BC Children's Hospital or Vancouver General Hospital Eye Care Centre in Vancouver, British Columbia, Canada...
March 30, 2016: British Journal of Ophthalmology
Oriel Spierer, Pedro F Monsalve, Terrence P OʼBrien, Eduardo C Alfonso, Daniel Gologorsky, Darlene Miller
PURPOSE: Reports on Achromobacter xylosoxidans ocular infections are increasing, drawing attention to its emerging role in infectious keratitis. The purpose of this study is to report the clinical features, antibiotic sensitivities, and visual outcomes of infectious keratitis secondary to Achromobacter xylosoxidans. METHODS: A microbiology database and clinical chart review was performed in all patients diagnosed with A. xylosoxidans keratitis at the Bascom Palmer Eye Institute between the years 1987 and 2014...
May 2016: Cornea
Lokeshwari Aruljyothi, Naveen Radhakrishnan, Venkatesh N Prajna, Prajna Lalitha
PURPOSE: To study the risk factors, microbiological profile and clinical outcomes of infectious keratitis affecting paediatric patients. STUDY DESIGN: Retrospective case series. METHODS: Review of case records of paediatric patients (0-16 years) diagnosed with infectious keratitis who presented to Aravind Eye Hospital, Madurai, India during January 2011 to December 2013. Demographic details, predisposing factors, microbiological investigations, clinical course and visual outcome were analysed...
February 25, 2016: British Journal of Ophthalmology
Joo Youn Oh, Jung Hwa Ko, Jin Suk Ryu, Hyun Ju Lee, Mee Kum Kim, Won Ryang Wee
PURPOSE: To investigate the expression of nucleotide-binding oligomerization domain-like receptors (NLRs) in human corneas with disease and corneal cells. METHODS: The expression of NOD1, NOD2, NLRP1, and NLRP3 was analyzed using real-time RT-PCR in (1) corneas with active infection, history of herpetic stromal keratitis (HSK), chronic allograft rejection, and limbal stem cell deficiency (LSCD), and (2) human corneal cells after lipopolysaccharide (LPS) stimulation...
February 22, 2016: Ocular Immunology and Inflammation
Joanne W Ho, Mark M Fernandez, Rachelle A Rebong, Alan N Carlson, Terry Kim, Natalie A Afshari
BACKGROUND: Given the rise in cases of fungal keratitis in recent years, this study was performed to better elucidate the microbiological profile, risk factors, and surgical intervention rates of fungal keratitis at a tertiary referral center in the Southeastern USA. FINDINGS: This is a retrospective case series of fungal keratitis infections treated at Duke University Eye Center from January 1, 1998, to October 6, 2008. Of the 4651 culture-proven corneal ulcers identified, 63 (1...
December 2016: Journal of Ophthalmic Inflammation and Infection
Michael D Wagoner, Jeffrey D Welder, Kenneth M Goins, Mark A Greiner
PURPOSE: To determine the incidence, ocular surface disease associations, microbiological profile, and clinical course of postoperative infections after implantation of the Boston type 1 keratoprosthesis (KPro-1). METHODS: A retrospective chart review was conducted of all cases of the KPro-1 performed at a tertiary eye care center between January 1, 2008, and December 31, 2014. RESULTS: Seventy-five KPro-1 procedures were included in the analysis...
April 2016: Cornea
Ching-Hsi Hsiao, Chi-Chin Sun, Lung-Kun Yeh, David H K Ma, Phil Y F Chen, Hsin-Chiung Lin, Hsin-Yuan Tan, Hung-Chi Chen, Shin-Yi Chen, Yhu-Chering Huang
PURPOSE: To investigate the distribution, current trends, and antibiotic susceptibility profiles of bacterial keratitis isolates over 10 years. METHODS: We retrospectively reviewed the microbiology records of all corneal scrapings undertaken for cultures at Chang Gung Memorial Hospital from 2003 through 2012. We identified bacterial isolates and verified antibiotic susceptibilities by using the disk diffusion method. The Mantel-Haenszel linear-by-linear association χ test was used to detect the trends...
March 2016: Cornea
Hemadevi Boomiraj, Vidyarani Mohankumar, Prajna Lalitha, Bharanidharan Devarajan
PURPOSE: MicroRNAs (miRNAs) are small, stable, noncoding RNA molecules with regulatory function and marked tissue specificity that posttranscriptionally regulate gene expression. However, their role in fungal keratitis remains unknown. The purpose of this study was to identify the miRNA profile and its regulatory role in fungal keratitis. METHODS: Normal donor (n = 3) and fungal keratitis (n = 5) corneas were pooled separately, and small RNA deep sequencing was performed using a sequencing platform...
December 2015: Investigative Ophthalmology & Visual Science
Seung-Jun Lee, Jang Hun Lee, Moosang Kim, Sang Beom Han, Joon Young Hyon
PURPOSE: To evaluate clinical features of infectious keratitis at a tertiary referral center in a rural area of Korea. RESULTS: This was a retrospective study. Medical records of 70 patients who were diagnosed with infectious keratitis and underwent corneal culture were reviewed. Data including demographics, predisposing factors, and microbiological profiles were collected and analyzed. RESULTS: Age distribution showed one peak at sixth and seventh decade, and 48 patients (68...
2015: International Medical Case Reports Journal
Chau-Minh Phan, Magdalena Bajgrowicz, Huayi Gao, Lakshman N Subbaraman, Lyndon W Jones
PURPOSE: Rapid drug release followed by a plateau phase is a common observation with drug delivery from contact lenses (CLs) when evaluated in a vial. The aim of this study was to compare the release of fluconazole from seven commercially available daily disposable CLs using a conventional vial-based method with a novel in vitro eye model. METHODS: An eye model was created using two 3-dimensional printed molds, which were filled with polydimethylsiloxane to obtain an inexpensive model that would mimic the eyeball and eyelid...
April 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"