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https://www.readbyqxmd.com/read/29334624/adequate-vitamin-d3-skin-synthesis-versus-erythema-risk-in-the-northern-hemisphere-midlatitudes
#1
Jakub Guzikowski, Janusz Krzyścin, Agnieszka Czerwińska, Weronika Raszewska
Health-optimum-exposure index (HOEI) is proposed to assess if the prescribed amount of vitamin D3 (target value) could be synthesized in the human skin without erythema appearance. It is defined as the ratio between the vitamin D3 quantity received during the maximum allowed outdoor exposure without erythema risk and the target value. Sunbathing is safe for HOEI>1 and 1/HOEI represents a part of minimal erythema dose (MED) necessary to obtain the target value. We examine the following targets: a vitamin D3 quantity equivalent to 1000 IU vitamin D3 taken orally, and an optimal vitamin D3 quantity defined by Krzyścin et al...
January 11, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29334549/cost-effectiveness-of-alternative-strategies-for-provision-of-hiv-pre-exposure-prophylaxis-for-people-who-inject-drugs
#2
Rui Fu, Douglas K Owens, Margaret L Brandeau
BACKGROUND: Oral HIV pre-exposure prophylaxis (PrEP) has been recommended as a means of HIV prevention among people who inject drugs (PWID) but, at current prices, is unlikely to be cost-effective for all PWID. OBJECTIVE: To determine the cost-effectiveness of alternative strategies for enrolling PWID in PrEP. DESIGN: Dynamic network model that captures HIV transmission and progression among PWID in a representative US urban center. OUTCOME MEASURES: HIV infections averted, discounted costs and quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs)...
January 13, 2018: AIDS
https://www.readbyqxmd.com/read/29334532/cost-effectiveness-and-improved-parent-and-provider-satisfaction-with-outpatient-management-of-pediatric-oncology-patients-with-low-risk-fever-and-neutropenia
#3
Abhishek Bavle, Amanda Grimes, Sibo Zhao, Daniel Zinn, Andrea Jackson, Binita Patel, Timothy Porea, Ankhi Dutta, Heidi Russell, Andras Heczey
On the basis of significant evidence for safety, the international pediatric fever and neutropenia committee recommends the identification and management of patients with "low-risk fever and neutropenia" (LRFN), outpatient with oral antibiotics, instead of traditional inpatient management. The aim of our study was to compare the cost-per-patient with these 2 strategies, and to evaluate parent and provider satisfaction with the outpatient management of LRFN. Between March 2016 and February 2017, 17 LRFN patients (median absolute neutrophil count, 90/μL) were managed at a single institution, per new guidelines...
January 12, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29334434/the-case-for-stabilized-stannous-fluoride-dentifrice-an-advanced-formulation-designed-for-patient-preference
#4
Tao He, Svetlana Farrell
Oral diseases, particularly caries and gingivitis, continue to be widespread. Incorporating a stabilized stannous fluoride dentifrice into patients' daily oral hygiene routine is a convenient, cost effective approach to improve and protect their oral health and the appearance of their smile. Unlike other common fluorides that only provide anti-caries benefits (e.g., sodium fluoride and sodium monofluorophosphate), stabilized stannous fluoride formulations have demonstrated broader and significantly greater protection, also reducing plaque, gingivitis, erosion, sensitivity, and halitosis...
December 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/29334297/perceptions-of-older-people-s-oral-health-care-among-nurses-working-in-geriatric-home-care
#5
Taru Aro, Marjo Laitala, Anna-Maija Syrjälä, Marja-Liisa Laitala, Jorma I Virtanen
OBJECTIVES: This study investigates nurses' self-reported experiences and perceptions of older people's oral health care using a qualitative method. METHODS: We interviewed 10 nurses working in geriatric home care who regularly visit and take care of older people in their homes. The interviews consisted of semi-structured questions. The interviews were then transcribed and analysed. RESULTS: All nurses were aware of the connection between oral health and general health, but more detailed knowledge about oral health was lacking and confidence in oral health care practices was limited...
January 15, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29333816/national-health-care-network-for-children-with-oral-clefts-organization-functioning-and-preliminary-outcomes
#6
Agustina Cassinelli, Nadia Pauselli, Agustina Piola, Claudia Martinelli, José L Alves de Azeved, María P Bidondo, Boris Groisman, Pablo Barbero, Rosa Liascovich, Ana Sala
INTRODUCTION: Oral clefts are major congenital anomalies that may affect the lip and/or palate, and that may also involve the nose and nostrils. In Argentina, their prevalence is approximately 15 per 10 000 births. In 2015, the Ministry of Health of Argentina created a national health care network for children with oral clefts in Argentina through the joint work with the National Registry of Congenital Anomalies (Red Nacional de Anomalías Congénitas, RENAC) (coordinating center for the national network) and the SUMAR Program...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333784/-ancient-human-jaw-osteomyelitis-in-chinese-yangshao-period-a-case-report
#7
Zhou Yawei, Gu Wanfa, Han Guohe
This article reported jaw osteomyelitis in ancient human bone specimens, helping us to understand the emergence of ancient human jaw osteomyelitis and other oral health conditions.
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29333368/oral-lesions-associated-with-human-immunodeficiency-virus-in-75-adult-patients-a-clinical-study
#8
Antoine Berberi, Georges Aoun
Objectives: The objective of this study was to investigate the presence of oral lesions in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients in a descriptive cross-sectional study, and to establish their presence according to levels of CD4+ cells (including the CD4+/CD8+ cell ratio). Materials and Methods: A total of 75 patients infected with HIV were included. Oral lesions were observed and classified using World Health Organization classification guidelines...
December 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/29333065/hepatitis-c-infection-in-patients-with-hereditary-bleeding-disorders-epidemiology-natural-history-and-management
#9
REVIEW
Nikolaos Papadopoulos, Vasiliki Argiana, Melanie Deutsch
Hereditary bleeding disorders include a group of diseases with abnormalities of coagulation. Prior to 1990, infection with hepatitis C virus (HCV) was mainly transmitted via pooled plasma products as a treatment for hereditary bleeding disorders. Anti-HCV positivity in these patients may be as high as >70% in some areas, while some of them have also been coinfected with human immunodeficiency virus. Since about 20% of HCV-infected patients clear the infection naturally, chronic HCV infection represents a significant health problem in this group of patients...
January 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29333040/pharmacological-screening-of-trachyspermum-ammi-for-antihyperlipidemic-activity-in-triton-x-100-induced-hyperlipidemia-rat-model
#10
Uzma Saleem, Saba Riaz, Bashir Ahmad, Mohammad Saleem
Background: Mortality rate is increasing due to cardiovascular problems throughout the world. These cardiac problems are directly associated with dyslipidemia. Aim: The aim of this study was to evaluate the antihyperlipidemic effect of aqueous extract and methanol extract of Trachyspermum ammi at 1 g/kg, 3 g/kg, and 5 g/kg dose levels in rats. Materials and Methods: For this purpose, 45 male albino rats were used and randomly divided into nine equal groups (n = 5)...
December 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/29332657/primary-oral-tuberculosis-on-the-tongue-mimicking-squamous-cell-carcinoma
#11
Karandeep Singh Arora, Sunny Garg, Prabhpreet Kaur, Shreeyam Mohapatra
Tuberculosis is chronic granulomatous disease with rare oral manifestations. But if so are overlooked by most of the health care professionals. Clinically, most of the times, a tuberculous ulcer may mimic an ulcer of malignant origin and may be misdiagnosed. So, keeping in mind the etiology and the nature of the ulcer, it should be differentially diagnosed and a histopathological examination should only confirm the final diagnosis of the ulcer.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29331717/in%C3%A2-vitro-dermal-bioaccessibility-of-selected-metals-in-contaminated-soil-and-mine-tailings-and-human-health-risk-characterization
#12
Laura T Chaparro Leal, Mert Guney, Gerald J Zagury
Dermal exposure to contaminated sites has generally received less attention than oral/inhalation exposure due to limited exposure scenarios and less perceived potential for toxicity, however, the risk can be significant for specific contaminants and scenarios. The present study aims to (1) measure Cr, Ni, Pb, and Zn contamination in soil and mine tailings samples (n = 7), (2) determine the dermal bioaccessibility of these metals via in vitro tests using two synthetic sweat formulations (EN 1811; NIHS 96-10), and (3) obtain dermal absorbed doses (DADs) for children's and adults' exposure scenarios and compare them to derived dermal reference values...
January 4, 2018: Chemosphere
https://www.readbyqxmd.com/read/29331393/oral-health-considerations-for-pediatric-patients-with-sickle-cell-disease
#13
REVIEW
Sahar Alrayyes, Anne-Ashley Compton, Nadia Kawar
No abstract text is available yet for this article.
January 10, 2018: Disease-a-month: DM
https://www.readbyqxmd.com/read/29331368/in-vitro-and-in-vivo-safety-analysis-of-enterococcus-faecium-2c-isolated-from-human-breast-milk
#14
Soodabeh Khalkhali, Naheed Mojgani
INTRODUCTION: Safety analysis of probiotic bacteria is an obligatory characteristic to be evaluated prior to application in food or pharmacological products. This study was designed to evaluate in vitro and in vivo safety parameters of Enterococcus faecium 2C strain, a probiotic candidate isolated from human breast milk. MATERIAL AND METHODS: E.faecium 2C was studied for its hemolytic activity and phenotypic antibiotics resistance profile. In vivo safety of the mentioned Enterococcus strain was studied by determining acute oral toxicity in Wistar Male rats...
January 10, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29331046/prevalence-severity-and-risk-factors-for-acute-exacerbations-of-nasal-and-sinus-symptoms-by-chronic-rhinosinusitis-status
#15
Jordan R Kuiper, Annemarie G Hirsch, Karen Bandeen-Roche, Agnes S Sundaresan, Bruce K Tan, Robert P Schleimer, Robert C Kern, Walter F Stewart, Brian S Schwartz
BACKGROUND: Nasal and sinus symptoms (NSS) are common to many health conditions, including chronic rhinosinusitis (CRS). Few studies have investigated the occurrence and severity of, and risk factors for, acute exacerbations of NSS (AENSS) by CRS status (current, past, or never met European Position Paper on Rhinosinusitis [EPOS] criteria for CRS). METHODS: Four seasonal questionnaires were mailed to a stratified random sample of Geisinger primary care patients...
January 13, 2018: Allergy
https://www.readbyqxmd.com/read/29330612/analysis-of-the-stomatognathic-system-of-children-according-orthodontic-treatment-needs
#16
Simone Cecílio Hallak Regalo, Bárbara de Lima Lucas, Kranya Victoria Díaz-Serrano, Nicolly Parente Ribeiro Frota, Isabela Hallak Regalo, Mariângela Salles Pereira Nassar, Mariah Acioli Righetti, Lígia Franco Oliveira, Lígia Maria Napolitano Gonçalves, Selma Siéssere, Marcelo Palinkas
PURPOSE: The present study evaluated electromyographic activity (EMG), masticatory performance, and tongue strength in children without and with orthodontic treatment needs. PATIENTS AND METHODS: A total of 90 children were screened and divided into the following groups: Group I (no treatment needed; mean age: 8.00 ± 0.43 years; n = 26), Group II (few malocclusions, treatment needed; mean age: 8.89 ± 0.43 years; n = 28), and Group III (slight-to-borderline treatment needed; mean age: 8...
January 12, 2018: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/29329957/safety-and-tolerability-of-a-novel-polyclonal-human-anti-mers-coronavirus-antibody-produced-from-transchromosomic-cattle-a-phase-1-randomised-double-blind-single-dose-escalation-study
#17
John H Beigel, Jocelyn Voell, Parag Kumar, Kanakatte Raviprakash, Hua Wu, Jin-An Jiao, Eddie Sullivan, Thomas Luke, Richard T Davey
BACKGROUND: Middle East respiratory syndrome (MERS) is a severe respiratory illness with an overall mortality of 35%. There is no licensed or proven treatment. Passive immunotherapy approaches are being developed to prevent and treat several human medical conditions where alternative therapeutic options are absent. We report the safety of a fully human polyclonal IgG antibody (SAB-301) produced from the hyperimmune plasma of transchromosomic cattle immunised with a MERS coronavirus vaccine...
January 9, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29329877/-attitudes-towards-cow-s-milk-protein-allergy-management-by-spanish-gastroenterologist
#18
Alicia Isabel Pascual Pérez, Alejandra Méndez Sánchez, Óscar Segarra Cantón, Beatriz Espin Jaime, Santiago Jiménez Treviño, Carlos Bousoño García, Juan José Díaz Martín
INTRODUCTION: Food allergy is an increasing health problem in the developed world. Cow's milk protein is the main cause of food allergy in infants. Without an appropriate diagnostic workup, there is a high risk of both over- and underdiagnosis and therefore, over and undertreatment. The objective of our study was to analyze the variability in cow's milk protein allergy (CMPA) management by pediatric gastroenterologists in Spain. METHODS: A fifty item questionnaire, including open and closed items in a Likert's scale from 0 to 5, was drafted and distributed through the Spanish Society for Pediatric Gastroenterology, Hepatology and Nutrition (SEGHNP) e-mail list...
January 9, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29329266/relative-validity-of-a-24-h-recall-in-assessing-intake-of-key-nutrients-in-a-cohort-of-australian-toddlers
#19
Elizabeth Beaton, Janine Wright, Gemma Devenish, Loc Do, Jane Scott
There is limited information concerning the dietary intake of toddlers in Australia. Consequently, there is a need for studies investigating toddler intake that use dietary assessment measures that are valid and place a low participant burden on caregivers. The aim of this study was to determine the relative validity of a single 24-h dietary recall (24HR) in measuring the intake of five nutrients in a cohort of Australian toddlers compared to a combined 24HR and 2-day estimated food record (2DFR). A single 24HR and a 2DFR were collected from a cohort of Australian toddlers (n = 699) at approximately 12 months of age as part of the Study of Mothers' and Infants' Life Events affecting oral health (SMILE) project...
January 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29329099/accumulation-patterns-and-risk-assessment-of-metals-and-metalloid-in-muscle-and-offal-of-free-range-chickens-cattle-and-goat-in-benin-city-nigeria
#20
Emmanuel Temiotan Ogbomida, Shouta M M Nakayama, Nesta Bortey-Sam, Balazs Oroszlany, Isioma Tongo, Alex Ajeh Enuneku, Ogbeide Ozekeke, Martins Oshioriamhe Ainerua, Iriagbonse Priscillia Fasipe, Lawrence Ikechukwu Ezemonye, Hazuki Mizukawa, Yoshinori Ikenaka, Mayumi Ishizuka
The use of free range animals for monitoring environmental health offers opportunities to detect exposure and assess the toxicological effects of pollutants in terrestrial ecosystems. Potential human health risk of dietary intake of metals and metalloid via consumption of offal and muscle of free range chicken, cattle and goats by the urban population in Benin City was evaluated. Muscle, gizzard, liver and kidney samples were analyzed for Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Cd, and Pb concentrations using inductively coupled plasma mass spectrometer (ICP-MS) while Hg was determined using Hg analyzer...
January 9, 2018: Ecotoxicology and Environmental Safety
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