keyword
MENU ▼
Read by QxMD icon Read
search

Leptospirosis review

keyword
https://www.readbyqxmd.com/read/29913535/thrombocytopenia-and-platelet-dysfunction-in-acute-tropical-infectious-diseases
#1
Indri Hapsari Putri, Rahajeng N Tunjungputri, Philip G De Groot, Andre J van der Ven, Quirijn de Mast
Thrombocytopenia is a well-known manifestation of acute tropical infectious diseases. The role of platelets in infections has received much attention recently because of their emerging activities in modulation of inflammatory responses, host defense, and vascular integrity. However, while many studies have addressed thrombocytopenia in tropical infections, abnormalities in platelet function have been largely overlooked. This is an important research gap, as platelet dysfunction may contribute to the bleeding tendency that characterizes some tropical infections...
June 18, 2018: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/29862254/leptospirosis-in-coastal-south-india-a-facility-based-study
#2
Ramesh Holla, Bhagwan Darshan, Latika Pandey, Bhaskaran Unnikrishnan, Nithin Kumar, Rekha Thapar, Prasanna Mithra, Vaman Kulkarni
Background: Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective: The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods: This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29846473/pathology-and-pathogenesis-of-human-leptospirosis-a-commented-review
#3
REVIEW
Thales De Brito, Ana Maria Gonçalves da Silva, Patrícia Antonia Estima Abreu
Leptospirosis is an acute bacterial septicemic febrile disease caused by pathogenic leptospires, which affect humans and animals in all parts of the world. Transmission can occur by direct contact with infected animals or, more commonly, through indirect contact with water or soil contaminated with urine from infected animals. Leptospires enter the body by penetrating mucous membranes or skin abrasions and disseminate through the hematogenic route. In humans, leptospirosis may cause a wide spectrum of symptoms...
2018: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29789961/illnesses-associated-with-freshwater-recreation-during-international-travel
#4
REVIEW
Daniel L Bourque, Joseph M Vinetz
PURPOSE OF REVIEW: International travel, adventure travel, and eco-tourism are increasing over the past few decades. This review aims to summarize the spectrum of infections associated with recreational freshwater activities and international travel. RECENT FINDINGS: Recreational water activities can be associated with a wide range of infections. Acute febrile illnesses due to leptospirosis and schistosomiasis are not uncommon in travelers following extensive freshwater exposure...
May 22, 2018: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/29758037/a-systematic-review-of-human-and-animal-leptospirosis-in-the-pacific-islands-reveals-pathogen-and-reservoir-diversity
#5
Vanina Guernier, Cyrille Goarant, Jackie Benschop, Colleen L Lau
BACKGROUND: The Pacific Islands have environmental conditions highly favourable for transmission of leptospirosis, a neglected zoonosis with highest incidence in the tropics, and Oceania in particular. Recent reports confirm the emergence and outbreaks of leptospirosis in the Pacific Islands, but the epidemiology and drivers of transmission of human and animal leptospirosis are poorly documented, especially in the more isolated and less developed islands. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a systematic review of human and animal leptospirosis within 25 Pacific Islands (PIs) in Polynesia, Melanesia, Micronesia, as well as Easter Island and Hawaii...
May 14, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29749356/advances-challenges-in-leptospiral-vaccine-development
#6
REVIEW
Garba Bashiru, Abdul Rani Bahaman
Considerable progress has been made in the field of leptospiral vaccines development since its first use as a killed vaccine in guinea pigs. Despite the fact that the immunity conferred is restricted to serovars with closely related lipopolysaccharide antigen, certain vaccines have remained useful, especially in endemic regions, for the protection of high-risk individuals. Other conventional vaccines such as the live-attenuated vaccine and lipopolysaccharide (LPS) vaccine have not gained popularity due to the reactive response that follows their administration and the lack of understanding of the pathogenesis of leptospirosis...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29672510/rodent-borne-diseases-and-their-public-health-importance-in-iran
#7
REVIEW
Mohammad Hasan Rabiee, Ahmad Mahmoudi, Roohollah Siahsarvie, Boris Kryštufek, Ehsan Mostafavi
BACKGROUND: Rodents are reservoirs and hosts for several zoonotic diseases such as plague, leptospirosis, and leishmaniasis. Rapid development of industry and agriculture, as well as climate change throughout the globe, has led to change or increase in occurrence of rodent-borne diseases. Considering the distribution of rodents throughout Iran, the aim of this review is to assess the risk of rodent-borne diseases in Iran. METHODOLOGY/PRINCIPAL FINDING: We searched Google Scholar, PubMed, Science Direct, Scientific Information Database (SID), and Magiran databases up to September 2016 to obtain articles reporting occurrence of rodent-borne diseases in Iran and extract information from them...
April 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29581051/febrile-illness-in-asia-gaps-in-epidemiology-diagnosis-and-management-for-informing-health-policy
#8
REVIEW
P Shrestha, T Roberts, A Homsana, T O Myat, J A Crump, Y Lubell, P N Newton
BACKGROUND: Increasing evidence is becoming available on the aetiology and management of fevers in Asia; the importance of these fevers has increased with the decline in the incidence of malaria. AIMS: To conduct a narrative review of the epidemiology and management of fevers in South and South-East Asia and to highlight gaps in our knowledge that impair evidence-based health policy decisions. SOURCES: A narrative review of papers published since 2012 on developments in fever epidemiology, diagnosis and treatment in South and South-East Asia...
March 23, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29518223/building-prognostic-models-for-adverse-outcomes-in-a-prospective-cohort-of-hospitalised-patients-with-acute-leptospirosis-infection-in-the-philippines
#9
Nathaniel Lee, Emi Kitashoji, Nobuo Koizumi, Talitha Lea V Lacuesta, Maricel R Ribo, Efren M Dimaano, Nobuo Saito, Motoi Suzuki, Koya Ariyoshi, Christopher M Parry
Leptospirosis is endemic to the Philippines. Ten per cent of cases will develop severe or fatal disease. Predicting progression to severity is difficult. Risk factors have been suggested, but few attempts have been made to create predictive models to guide clinical decisions. We present two models to predict the risk of mortality and progression to severe disease. Data was used from a prospective cohort study conducted between 2011 and 2013 in San Lazaro Hospital, Manila. Predictive factors were identified from a literature review...
December 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29518084/childhood-leptospirosis-in-an-industrialized-country-population-based-study-in-okinawa-japan
#10
Kouki Tomari, Takao Toyokawa, Takuto Takahashi, Tetsuya Kakita, Sho Okano, Hisako Kyan, Naoya Tonegawa, Teppei Okawa, Takashi Matsuoka, Tsutomu Matsumora
Leptospirosis is considered underdiagnosed because of its nonspecific presentation and lack of proper understanding of its epidemiology. Early diagnosis and treatment are crucial. However, few data are available on confirmed leptospirosis cases in children in industrialized countries. We therefore aimed to describe epidemiologic and clinical characteristics of laboratory-confirmed childhood leptospirosis in Okinawa, Japan. We reviewed the national surveillance data of pediatric leptospirosis in Okinawa, Japan from January 2003 through December 2015...
March 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29514645/development-and-validation-of-a-new-knowledge-attitude-belief-and-practice-questionnaire-on-leptospirosis-in-malaysia
#11
Wan Mohd Zahiruddin, Wan Nor Arifin, Shafei Mohd-Nazri, Surianti Sukeri, Idris Zawaha, Rahman Abu Bakar, Rukman Awang Hamat, Osman Malina, Tengku Zetty Maztura Tengku Jamaludin, Arumugam Pathman, Ab Rahman Mas-Harithulfadhli-Agus, Idris Norazlin, Binti Samsudin Suhailah, Siti Nor Sakinah Saudi, Nurul Munirah Abdullah, Noramira Nozmi, Abdul Wahab Zainuddin, Daud Aziah
BACKGROUND: In Malaysia, leptospirosis is considered an endemic disease, with sporadic outbreaks following rainy or flood seasons. The objective of this study was to develop and validate a new knowledge, attitude, belief and practice (KABP) questionnaire on leptospirosis for use in urban and rural populations in Malaysia. METHODS: The questionnaire comprised development and validation stages. The development phase encompassed a literature review, expert panel review, focus-group testing, and evaluation...
March 7, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29458845/leptospirosis-in-human-biomarkers-in-host-immune-responses
#12
REVIEW
Chin Vk, Lee Ty, Lim Wf, Wan Shahriman Ywy, Syafinaz An, Zamberi S, Maha A
Leptospirosis remains one of the most widespread zoonotic diseases caused by spirochetes of the genus Leptospira, which accounts for high morbidity and mortality globally. Leptospiral infections are often found in tropical and subtropical regions, with people exposed to contaminated environments or animal reservoirs are at high risk of getting the infection. Leptospirosis has a wide range of clinical manifestations with non-specific signs and symptoms and often misdiagnosed with other acute febrile illnesses at early stage of infection...
March 2018: Microbiological Research
https://www.readbyqxmd.com/read/29452258/recent-findings-related-to-immune-responses-against-leptospirosis-and-novel-strategies-to-prevent-infection
#13
Frédérique Vernel-Pauillac, Catherine Werts
What are the new approaches and emerging ideas to prevent leptospirosis, a neglected bacterial re-emerging zoonotic disease? How do Leptospira interrogans escape the host defenses? We aim here to review and discuss the most recent literature that provides some answers to these questions, in particular data related to a better understanding of adaptive and innate immunity towards leptospires, and design of vaccines. This is an opinion paper, not a comprehensive review. We will try to highlight the new strategies and technologies boosting the search for drugs and vaccines...
February 13, 2018: Microbes and Infection
https://www.readbyqxmd.com/read/29445617/pathogenic-leptospira-advances-in-understanding-the-molecular-pathogenesis-and-virulence
#14
REVIEW
Ciamak Ghazaei
Leptospirosis is a common zoonotic disease has emerged as a major public health problem, with developing countries bearing disproportionate burdens. Although the diverse range of clinical manifestations of the leptospirosis in humans is widely documented, the mechanisms through which the pathogen causes disease remain undetermined. In addition, leptospirosis is a much-neglected life-threatening disease although it is one of the most important zoonoses occurring in a diverse range of epidemiological distribution...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29388363/zoonotic-pathogens-from-feral-swine-that-pose-a-significant-threat-to-public-health
#15
REVIEW
V R Brown, R A Bowen, A M Bosco-Lauth
The natural fecundity of suids, great ability to adapt to new habitats and desire for local hunting opportunities leading to translocation of feral pigs to regions where they are not yet established have all been instrumental in the home range expansion of feral swine. Feral swine populations in the United States continue to expand, wreaking havoc on agricultural lands, further compromising threatened and endangered species, and posing a microbiological threat to humans, domestic livestock and companion animals...
January 31, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29364411/-prevention-diagnosis-and-treatment-of-pediatric-infections-during-natural-disasters
#16
Flavia Morán, Theresa J Ochoa
The objective of this review was to provide guidelines regarding the diagnosis, treatment, and prevention of the most common infectious diseases in children during natural disasters, including floods such as those that occurred in the summer of 2017 in Peru. This instrument should be used by physicians and health personnel working in primary health care. The management of diarrheal, respiratory, skin, and eye diseases, vector-transmitted diseases such as dengue, chikungunya, and Zika, and zoonoses such as leptospirosis is discussed...
October 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29236923/whole-genome-sequencing-of-leptospira-interrogans-from-southern-brazil-genetic-features-of-a-highly-virulent-strain
#17
Sérgio Jorge, Frederico Schmitt Kremer, Natasha Rodrigues de Oliveira, Gabrielle de Oliveira Sanches Valerio Navarro, Amanda Munari Guimarães, Christian Domingues Sanchez, Rafael Danelon Dos Santos Woloski, Karine Forster Ridieri, Vinícius Farias Campos, Luciano da Silva Pinto, Odir Antônio Dellagostin
BACKGROUND Leptospirosis is the most widespread zoonotic disease. It is caused by infection with pathogenic Leptospira species, of which over 300 serovars have been described. The accurate identification of the causative Leptospira spp. is required to ascertain the pathogenic status of the local isolates. OBJECTIVES This study aimed to obtain the complete genome sequence of a virulent Leptospira interrogans strain isolated from southern Brazil and to describe its genetic features. METHODS The whole genome was sequenced by next-generation sequencing (Ion Torrent)...
February 2018: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29229654/protocol-for-developing-a-database-of-zoonotic-disease-research-in-india-dozoori
#18
Pranab Chatterjee, Soumyadeep Bhaumik, Abhimanyu Singh Chauhan, Manish Kakkar
INTRODUCTION: Zoonotic and emerging infectious diseases (EIDs) represent a public health threat that has been acknowledged only recently although they have been on the rise for the past several decades. On an average, every year since the Second World War, one pathogen has emerged or re-emerged on a global scale. Low/middle-income countries such as India bear a significant burden of zoonotic and EIDs. We propose that the creation of a database of published, peer-reviewed research will open up avenues for evidence-based policymaking for targeted prevention and control of zoonoses...
December 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/29217379/major-epidemiological-factors-associated-with-leptospirosis-in-malaysia
#19
REVIEW
Bashiru Garba, Abdul Rani Bahaman, Siti Khairani Bejo, Zunita Zakaria, Abdul Rahim Mutalib, Faruku Bande
INTRODUCTION: Leptospirosis is a zoonotic disease caused by a diverse pathogenic leptospira species and serovars. The disease is transmitted directly following contact with infected urine and other body fluids or indirectly after contact with water or soil contaminated with infected urine. OBJECTIVES: While a wide range of domestic and wild animals are known to be reservoirs of the disease, occupation, international travel and recreation are beginning to assume a center stage in the transmission of the disease...
February 2018: Acta Tropica
https://www.readbyqxmd.com/read/29122476/efficacy-of-leptospiral-commercial-vaccines-on-the-protection-against-an-autochtonous-strain-recovered-in-brazil
#20
Rafael Bazaglia Sonada, Sérgio Santos de Azevedo, Francisco Rafael Martins Soto, Diego Figueiredo da Costa, Zenaide Maria de Morais, Gisele Oliveira de Souza, Amane Paldês Gonçales, Fabiana Miraglia, Sílvio Arruda Vasconcellos
In swine and bovines, leptospirosis prevention and control is carried out via vaccination of susceptible animals using bacterins. However, the efficiency of leptospirosis vaccines has been questioned. This work aimed to investigate the potency of five leptospirosis vaccines sold commercially in Brazil, challenging the animals with one autochthonous strain of Leptospira, Canicola serovar, denoted LO4, isolated from swine. The standard protocol was followed, and renal carriers of Leptospira were identified among the surviving animals by culture and PCR...
April 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
keyword
keyword
25685
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"