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https://www.readbyqxmd.com/read/28306724/respiratory-dna-viruses-are-undetectable-in-nasopharyngeal-secretions-from-adenotonsillectomized-children
#1
Ronaldo Bragança Martins, Lucas Penna Rocha, Mirela Moreira Prates, Talita Bianca Gagliardi, Balduino Biasoli, Marcelo Junqueira Leite, Guilherme Buzatto, Miguel Angelo Hyppolito, Davi Casale Aragon, Edwin Tamashiro, Fabiana Cardoso Pereira Valera, Eurico Arruda, Wilma Terezinha Anselmo-Lima
Respiratory viruses are frequently detected in association with chronic tonsillar hypertrophy in the absence of symptoms of acute respiratory infection (ARI). The present analysis was done in follow-up to a previous clinical study done by this same group. Nasopharyngeal washes (NPWs) were obtained from 83 of 120 individuals at variable times post adenotonsillectomy, in the absence of ARI symptoms. A look back at virus detection results in NPWs from the same 83 individuals at the time of tonsillectomy revealed that 73...
2017: PloS One
https://www.readbyqxmd.com/read/28302206/-relationship-between-viral-load-of-human-bocavirus-and-clinical-characteristics-in-children-with-acute-lower-respiratory-tract-infection
#2
Xiao-Fang Ding, Bing Zhang, Li-Li Zhong, Le-Yun Xie, Ni-Guang Xiao
OBJECTIVE: To investigate the prevalence of human bocavirus (HBoV) in children with acute lower respiratory tract infection and to explore the relationship between the viral load of HBoV and the clinical characteristics of acute lower respiratory tract infection in children. METHODS: A total of 1 554 nasopharyngeal aspirates from children who were hospitalized due to acute lower respiratory tract infection between March 2011 and March 2014 were collected. Quantitative real-time PCR was used to detect 12 RNA and 2 DNA viruses, adenovirus (ADV) and HBoV, and to measure the viral load of HBoV in HBoV-positive children...
March 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28301570/human-metapnuemovirus-infections-in-hospitalized-children-and-comparison-with-other-respiratory-viruses-2005-2014-prospective-study
#3
María Luz García-García, Cristina Calvo, Cristina Rey, Beatriz Díaz, Maria Del Mar Molinero, Francisco Pozo, Inmaculada Casas
BACKGROUND: Human metapneumovirus (HMPV) has an important etiological role in acute lower respiratory infections in children under five years. Our objectives were to estimate the relative contribution of HMPV to hospitalization in children with acute respiratory infection, to define the clinical and epidemiological features of HMPV single and multiple infections, and to compare HMPV infections with respiratory syncytial virus (HRSV), rhinovirus (HRV), adenovirus and human bocavirus infections in the same population...
2017: PloS One
https://www.readbyqxmd.com/read/28262277/-the-interactions-between-microorganisms-and-the-small-airways-a-paediatric-focus
#4
REVIEW
J de Blic, J Brouard, A Vabret, A Deschildre
The spectrum of respiratory viruses is expanding and emerging diseases have been described regularly over the last fifteen years. The origin of these emerging respiratory viruses may be zoonotic (by crossing species barrier, after changes to RNA viruses such as avian influenza virus type A or coronaviruses), or related to the use of new identification techniques (metapneumovirus, bocavirus). The relationship between bronchiolitis and asthma is now better understood thanks to prospective follow up of birth cohorts...
February 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/28231295/the-pathogens-profile-in-children-with-otitis-media-with-effusion-and-adenoid-hypertrophy
#5
G P Buzatto, E Tamashiro, J L Proenca-Modena, T H Saturno, M C Prates, T B Gagliardi, L R Carenzi, E T Massuda, M A Hyppolito, F C P Valera, E Arruda, W T Anselmo-Lima
OBJECTIVES: To evaluate the presence of viruses and bacteria in middle ear and adenoids of patients with and without otitis media with effusion (OME). METHODS: Adenoid samples and middle ear washes (MEW) were obtained from children with OME associated with adenoid hypertrophy undergoing adenoidectomy and tympanostomy, and compared to those obtained from patients undergoing cochlear implant surgery, as a control group. Specific DNA or RNA of 9 respiratory viruses (rhinovirus, influenza virus, picornavirus, syncytial respiratory virus, metapneumovirus, coronavirus, enterovirus, adenovirus and bocavirus) and 5 bacteria (S...
2017: PloS One
https://www.readbyqxmd.com/read/28215586/role-of-human-bocavirus-in-idiopathic-pulmonary-fibrosis
#6
LETTER
Wolfram Windisch, Verena Schildgen, Oliver Schildgen
No abstract text is available yet for this article.
February 17, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28198551/prevalence-and-clinical-profile-of-human-bocavirus-in-children-with-acute-gastroenteritis-in-chengdu-west-china-2012-2013
#7
Tao Zhou, Yuhang Chen, Jiayi Chen, Pengwei Hu, Tianli Zheng, Xin Xu, Xiaofang Pei
Viral acute gastroenteritis (AGE) is a major cause of mortality in childhood and leads to hospitalization in developing countries. Human bocavirus (HBoV) is a newly described virus associated with gastroenteritis. However, little is known about the clinical and epidemiological profile of human bocavirus (HBoV) in pediatric population in Chengdu, China. Between January 2012 and December 2013, 346 fecal samples from children admitted to hospital with acute gastroenteritis were tested for the presence of HBoV as well as other gastroenteritis viruses...
February 15, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28186546/case-control-assessment-of-the-roles-of-noroviruses-human-bocaviruses-2-3-and-4-and-novel-polyomaviruses-and-astroviruses-in-acute-childhood-diarrhea
#8
Rimma Melamed, Gregory A Storch, Lori R Holtz, Eileen J Klein, Brittany Herrin, Phillip I Tarr, Donna M Denno
No abstract text is available yet for this article.
February 10, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28178324/correction-b-cell-responses-to-human-bocaviruses-1-4-new-insights-from-a-childhood-follow-up-study
#9
Kalle Kantola, Lea Hedman, Laura Tanner, Ville Simell, Marjaana Mäkinen, Juulia Partanen, Mohammadreza Sadeghi, Riitta Veijola, Mikael Knip, Jorma Ilonen, Heikki Hyöty, Jorma Toppari, Olli Simell, Klaus Hedman, Maria Söderlund-Venermo
[This corrects the article DOI: 10.1371/journal.pone.0139096.].
2017: PloS One
https://www.readbyqxmd.com/read/28160215/the-impact-of-the-extreme-amazonian-flood-season-on-the-incidence-of-viral-gastroenteritis-cases
#10
Carmen Baur Vieira, Adriana de Abreu Corrêa, Michele Silva de Jesus, Sérgio Luiz Bessa Luz, Peter Wyn-Jones, David Kay, Mônica Simões Rocha, Marize Pereira Miagostovich
During the Amazonian flood season in 2012, the Negro River reached its highest level in 110 years, submerging residential and commercial areas which appeared associated with an elevation in the observed gastroenteritis cases in the city of Manaus. The aim of this study was to evaluate the microbiological water quality of the Negro River basin during this extreme flood to investigate this apparent association between the illness cases and the population exposed to the contaminated waters. Forty water samples were collected and analysed for classic and emerging enteric viruses...
February 3, 2017: Food and Environmental Virology
https://www.readbyqxmd.com/read/28144057/respiratory-viruses-in-acute-exacerbations-of-chronic-obstructive-pulmonary-disease
#11
Parvaiz A Koul, Hyder Mir, Shabir Akram, Varsha Potdar, Mandeep S Chadha
OBJECTIVE: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) cause significant morbidity, mortality, and an inexorable decline of lung function. Data from developed countries have shown viruses to be important causes of AECOPD, but data from developing countries like India are scant. We set out to determine the contribution of viruses in the causation of hospitalized patients with AECOPD. METHODS: Twin nasopharyngeal/oropharyngeal swabs collected from 233 patients admitted with an acute AECOPD and tested for respiratory viruses including respiratory syncytial virus A and B, parainfluenza were (PIV) 1, 2, 3, and 4, human metapneumovirus (hMPV) A and B, influenza A and B, enterovirus, corona NL65, OC43, and 229E viruses, adenovirus 2 and 4, rhinovirus, and bocavirus, by duplex real time reverse-transcription polymerase chain reaction (qRT-PCR) using CDC approved primers and probes...
January 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28132571/the-diagnosis-and-management-of-respiratory-viral-infections-in-cystic-fibrosis
#12
William Flight, Andrew Jones
Respiratory viruses, such as those that cause influenza and the common cold, are a regular feature of life for the entire human population. Among people with CF, these viruses are associated with prolonged respiratory illness and show a clear association with pulmonary exacerbations which in turn are associated with lung function decline and risk of death. Human rhinovirus is the most commonly encountered respiratory viral pathogen in CF although adenovirus, bocavirus, coronavirus, influenza, parainfluenza, metapneumovirus and respiratory syncytial virus are all also responsible for infections in this population...
February 3, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28122984/parvovirus-expresses-a-small-noncoding-rna-that-plays-an-essential-role-in-virus-replication
#13
Zekun Wang, Weiran Shen, Fang Cheng, Xuefeng Deng, John F Engelhardt, Ziying Yan, Jianming Qiu
Human bocavirus 1 (HBoV1) belongs to species Primate bocaparvovirus of the genus Bocaparvovirus of the Parvoviridae family. HBoV1 causes acute respiratory tract infections in young children and has a selective tropism for the apical surface of well-differentiated human airway epithelia (HAE). In this study, we identify an additional HBoV1 gene, bocavirus-transcribed small non-coding RNA (BocaSR) within the 3' non-coding region (nt 5199-5338) of the viral genome of positive sense. BocaSR is transcribed by RNA polymerase III (Pol III) from an intragenic promoter at similar levels to that of the capsid protein-coding mRNA and is essential for replication of the viral DNA in both transfected HEK293 and infected HAE cells...
January 25, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28115263/investigation-of-viral-infection-in-idiopathic-pulmonary-fibrosis-among-iranian-patients-in-tehran
#14
Pouya Moradi, Hossein Keyvani, Seyed-Ali Javad Mousavi, Mohammad Hadi Karbalaie Niya, Maryam Esghaei, Farah Bokharaei-Salim, Angila Ataei-Pirkooh, Seyed Hamidreza Monavari
AIM OF THE STUDY: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease, which can be lethal with chronic complications. Viral infections may be associated with IPF and other fibrotic lung diseases. In the present study, we investigate for the first time in Iran the related viral etiology of IPF in order to detect three respiratory viruses; human adenovirus, enterovirus and bocavirus. MATERIALS AND METHODS: In this cross-sectional study which was supported by Iran University of Medical Sciences, Tehran, Iran...
March 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28090592/the-first-genome-sequences-of-human-bocaviruses-from-vietnam
#15
Tran Tan Thanh, Hoang Minh Tu Van, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Nguyen To Anh, Ha Manh Tuan, Ho Van Hien, Nguyen Manh Tuong, Trinh Trung Kien, Truong Huu Khanh, Le Nguyen Thanh Nhan, Nguyen Thanh Hung, Nguyen Van Vinh Chau, Guy Thwaites, H Rogier van Doorn, Le Van Tan
As part of an ongoing effort to generate complete genome sequences of hand, foot and mouth disease-causing enteroviruses directly from clinical specimens, two complete coding sequences and two partial genomic sequences of human bocavirus 1 (n=3) and 2 (n=1) were co-amplified and sequenced, representing the first genome sequences of human bocaviruses from Vietnam. The sequences may aid future study aiming at understanding the evolution of the pathogen.
November 16, 2016: Wellcome Open Res
https://www.readbyqxmd.com/read/28059631/acute-necrotizing-encephalopathy-causing-human-bocavirus
#16
Ayse Betul Ergul, Umit Altug, Kursad Aydin, Ahmet Sami Guven, Yasemin Altuner Torun
Acute necrotizing encephalopathy is characterized by multiple, symmetrical lesions involving the thalamus, brainstem, cerebellum, and white matter and develops secondarily to viral infections. Influenza viruses are the most common etiological agents. Here, we present the first case of acute necrotizing encephalopathy to develop secondarily to human bocavirus. A 3-year-old girl presented with fever and altered mental status. She had had a fever, cough, and rhinorrhea for five days. The patient was admitted to the intensive care unit with an initial diagnosis of encephalitis when vomiting, convulsions, and loss of consciousness developed...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28032197/molecular-detection-and-characterization-of-picobirnaviruses-in-piglets-with-diarrhea-in-thailand
#17
Lauren Wilburn, Arpaporn Yodmeeklin, Pakawat Kochjan, Wilaiporn Saikruang, Kattareeya Kumthip, Pattara Khamrin, Niwat Maneekarn
Picobirnavirus (PBV) is a small, bi-segmented, double-stranded RNA virus. Taxonomically, the genus Picobirnavirus belongs to the Picobirnaviridae family. PBV infects a wide range of hosts and causes opportunistic infections, but its role in diarrheal disease remains unclear. To determine the prevalence and genetic diversity of porcine PBVs in Northern Thailand, 380 fecal samples collected from diarrheic and non-diarrheic piglets, raised in 22 pig farms, were tested for the presence of PBV. Reverse-transcription PCR (RT-PCR) was performed using primer sets specific to the RNA-dependent RNA polymerase (RdRp) gene...
April 2017: Archives of Virology
https://www.readbyqxmd.com/read/27990436/human-bocavirus-in-korean-children-with-gastroenteritis-and-respiratory-tract-infections
#18
Eun Jin Lee, Han-Sung Kim, Hyun Soo Kim, Jae-Seok Kim, Wonkeun Song, MiYoung Kim, Young Kyung Lee, Hee Jung Kang
Human bocaviruses (HBoVs) are suggested to be etiologic agents of childhood respiratory and gastrointestinal infections. There are four main recognized genotypes of HBoVs (HBoV1-4); the HBoV-1 genotype is considered to be the primary etiologic agent in respiratory infections, whereas the HBoV2-4 genotypes have been mainly associated with gastrointestinal infections. The aim of the present study was to determine the distribution of HBoV genotypes in children with respiratory or gastrointestinal infections in a hospital in Korea...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27943329/viral-pathogens-among-elderly-people-with-acute-respiratory-infections-in-shanghai-china-preliminary-results-from-a-laboratory-based-surveillance-2012-2015
#19
Chuchu Ye, Weiping Zhu, Jianxing Yu, Zhongjie Li, Yifei Fu, Yajia Lan, Shengjie Lai, Yuanping Wang, Lifeng Pan, Qiao Sun, Genming Zhao
Acute respiratory infections (ARIs), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. The clinical and pathological features of elderly people with ARIs need to be identified for disease intervention. From January 1(st) , 2012 through December 31(st) , 2015, respiratory specimens from patients above 60 years old with ARIs were collected from the outpatient and inpatient settings of six sentinel hospitals in Pudong New Area...
December 12, 2016: Journal of Medical Virology
https://www.readbyqxmd.com/read/27907010/viral-metagenomic-analysis-displays-the-co-infection-situation-in-healthy-and-pmws-affected-pigs
#20
Anne-Lie Blomström, Caroline Fossum, Per Wallgren, Mikael Berg
The development of high-throughput sequencing technologies have allowed the possibility to investigate and characterise the entire microbiome of individuals, providing better insight to the complex interaction between different microorganisms. This will help to understand how the microbiome influence the susceptibility of secondary agents and development of disease. We have applied viral metagenomics to investigate the virome of lymph nodes from Swedish pigs suffering from the multifactorial disease postweaning multisystemic wasting syndrome (PMWS) as well as from healthy pigs...
2016: PloS One
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