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https://www.readbyqxmd.com/read/29145709/defining-a-unified-vascular-phenotype-in-systemic-sclerosis
#1
REVIEW
Yannick Allanore, Oliver Distler, Marco Matucci-Cerinic, Christopher P Denton
Microcirculation impairment and related vasculopathy is a hallmark of systemic sclerosis. Digital ulcers are second only to Raynaud's phenomenon as a vascular complication occurring in scleroderma patients. Digital ulcers are painful and generate disability. Furthermore, patients may develop recurrent digital ulcers and one may ask whether the outcomes of such patients might be different to those of unaffected ones. Recently several registries have provided relevant information about digital ulcers. Male sex and severe skin disease seem to be the main associated factors observed in several registries...
November 16, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29145572/difference-in-clinical-course-genetics-and-the-microbiome-between-familial-and-sporadic-inflammatory-bowel-diseases
#2
Nienke Z Borren, Grace Conway, John J Garber, Hamed Khalili, Shrish Budree, Himel Mallick, Vijay Yajnik, Ramnik J Xavier, Ashwin N Ananthakrishnan
Objective: Family history is the strongest risk factor for developing Crohn's disease (CD) or ulcerative colitis (UC). We investigated whether the proximity of relationship with the affected relative and concordance for type of IBD modifies the effect of family history on phenotype and disease severity. Design: This cross-sectional study included patients with a confirmed diagnosis of IBD in a clinical registry. Family history of IBD was assessed by a questionnaire ascertaining presence of disease in a 1 st degree, 2 nd degree or a distant relative...
November 14, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29145562/ulcerative-colitis-endoscopic-index-of-severity-is-feasible-and-useful-for-endoscopic-activity-evaluation-in-ulcerative-colitis-patients-in-real-life-setting
#3
Cristiano Pagnini, Benedetta Maria Mariani, Roberto Lorenzetti
No abstract text is available yet for this article.
November 14, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29145535/atypical-microbial-isolates-from-infected-diabetic-foot-ulcers-a-case-series-from-greece
#4
Maria Demetriou, Nikolaos Papanas, Periklis Panagopoulos, Maria Panopoulou, Efstratios Maltezos
No abstract text is available yet for this article.
July 2017: Review of Diabetic Studies: RDS
https://www.readbyqxmd.com/read/29145313/the-importance-of-family-caregiving-to-achieving-palliative-care-at-home-a-case-report-of-end-of-life-breast-cancer-in-an-area-struck-by-the-2011-fukushima-nuclear-crisis-a-case-report
#5
Akihiko Ozaki, Masaharu Tsubokura, Claire Leppold, Toyoaki Sawano, Manabu Tsukada, Tsuyoshi Nemoto, Kazuhiro Kosugi, Yoshitaka Nishikawa, Shigeaki Kato, Hiromichi Ohira
RATIONALE: The primary setting of palliative care has shifted from inpatient care to patients' residences. Family caregiving is essential for patients with life-limiting illnesses to receive palliative care at home, however little information is available regarding potential interventions to achieve palliative homecare for those without sufficient support from family members in various settings, including disasters. PATIENT CONCERNS: In March 2011, Fukushima, Japan experienced an earthquake, tsunami and nuclear disaster...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144832/postoperative-complications-of-dermis-fat-autografts-in-the-anophthalmic-socket
#6
Victoria Starks, Suzanne K Freitag
Reconstruction of the anophthalmic socket allows the use of an ocular prosthesis and rehabilitation of facial appearance. Dermis-fat grafting is one option in volume augmentation of the anophthalmic socket and presents unique benefits, including increased surface area within the socket and the ability to grow with pediatric patients. Postoperative complications of this procedure are relatively common. Minor complications, such as graft hirsutism, keratinization, and conjunctival cysts or granulomas, are managed easily by observation or simple intervention...
November 16, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29144786/venous-leg-ulceration-in-an-intravenous-drug-user
#7
Helen Fearnley, Jorge Fernandes
No abstract text is available yet for this article.
November 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29144784/diabetic-foot-ulcer
#8
Joanne McClennon
No abstract text is available yet for this article.
November 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29144781/non-healing-venous-leg-ulcer
#9
Helen Dawkins
No abstract text is available yet for this article.
November 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29144779/heavily-exuding-venous-leg-ulcer-with-suspected-biofilm
#10
Sarah Pankhurst
No abstract text is available yet for this article.
November 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29144778/exuding-venous-leg-ulcer-with-signs-of-biofilm
#11
Robert Oldfield
No abstract text is available yet for this article.
November 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29144776/extremely-painful-venous-leg-ulcer
#12
Helen Fearnley, Jorge Fernandes
No abstract text is available yet for this article.
November 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29144035/multiple-ulcerated-lesions-in-a-child
#13
Stefanie Cubelli, Syed Abedi, Silvija P Gottesman, Jacqueline M Junkins-Hopkins
No abstract text is available yet for this article.
November 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29143961/upregulation-of-epidermal-gap-junctional-proteins-in-patients-with-venous-disease
#14
M Kanapathy, R Simpson, L Madden, C Thrasivoulou, A Mosahebi, D L Becker, T Richards
BACKGROUND: Leg ulceration is a feared complication of venous insufficiency. It is not known whether varicose veins predispose skin to poor wound healing. The expression pattern of gap junctional protein connexin, a known marker of poor wound healing, was investigated across various stages of venous disease. METHODS: Patients undergoing intervention for varicose veins were assessed according to the Clinical Etiologic Anatomic Pathophysiologic (CEAP) classification of varicose veins...
November 16, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/29143724/gastric-lymphoma-association-with-helicobacter-pylori-outer-membrane-protein-q-hopq-and-cytotoxic-pathogenicity-activity-island-cpai-genes
#15
J Yakoob, Z Abbas, Z Ahmad, K Tariq, S Awan, K Mustafa, R Khan
B-cell non-Hodgkin lymphoma (B-cell NHL) is the second commonest malignancy in the stomach. We determined the distribution of Helicobacter pylori outer membrane protein Q (HopQ) allelic type, cytotoxin-associated gene (cag)-pathogenicity activity island (cag-PAI) and vacuolation activating cytotoxin A (vacA) genes, respectively, in patients with B-cell NHL. We also compared them with their distribution in non-ulcer dyspepsia (NUD). H. pylori was cultured from gastric biopsy tissue obtained at endoscopy. Polymerase chain reaction was performed...
November 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/29142544/effect-of-oil-gauze-silver-dressings-on-diabetic-foot-ulcers-in-the-elderly
#16
Chang Yan Dong, Wen Juan Liu, Rong Xiang Chi, Hong Du
Objective: To compare the clinical efficacy and safety of oil gauze silver dressing and silver ions dressing on diabetic ulcers in elderly outpatients. Methods: Twenty-two patients with Type-2 diabetic foot ulcers were included in the study conducted at Yantai Yuhuangding Hospital between April 2013 and April 2014. At the time of enrolment they were divided into the silver ions and oil gauze silver groups based on the order of admission. Dressings were changed twice weekly until the ulcer had healed...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29142525/irritable-bowel-syndrome-like-symptoms-associated-with-endoscopic-activity-predict-ulcerative-colitis-relapse-in-patients-with-clinical-remission
#17
Nobuhiko Fukuba, Shunji Ishihara, Kousaku Kawashima, Yoshiyuki Mishima, Naoki Oshima, Yoshikazu Kinoshita
No abstract text is available yet for this article.
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29142523/steroid-refractory-extensive-enteritis-complicated-by-ulcerative-colitis-successfully-treated-with-adalimumab
#18
Shinji Okabayashi, Taku Kobayashi, Tomohisa Sujino, Ryo Ozaki, Satoko Umeda, Takahiko Toyonaga, Eiko Saito, Masaru Nakano, Maria Carla Tablante, Shojiroh Morinaga, Toshifumi Hibi
Extracolonic involvement of the gastrointestinal tract is extremely uncommon in ulcerative colitis (UC) and rarely found in the upper gastrointestinal tract or in postoperative cases since it typically responds to steroids. Here we report a case of UC complicated by extensive ileal inflammation that was refractory to steroids. A 20-year-old man was diagnosed with UC of typical pancolitis without ileal involvement and started treatment with pH-dependent mesalazine and oral prednisolone. Although his symptoms transiently resolved, the condition flared when the steroid dose was tapered down...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29142512/non-steroidal-anti-inflammatory-drug-induced-enteropathy
#19
REVIEW
Sung Jae Shin, Choong-Kyun Noh, Sun Gyo Lim, Kee Myung Lee, Kwang Jae Lee
Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel injuries caused by NSAIDs, and new endoscopic techniques such as capsule endoscopy and double balloon endoscopy can help in detecting such injuries. This article reviewed the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of small bowel injuries caused by NSAIDs...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29142473/genetic-associations-with-adverse-events-from-anti-tumor-necrosis-factor-therapy-in-inflammatory-bowel-disease-patients
#20
Daniel Lew, Soon Man Yoon, Xiaofei Yan, Lori Robbins, Talin Haritunians, Zhenqiu Liu, Dalin Li, Dermot Pb McGovern
AIM: To study the type and frequency of adverse events associated with anti-tumor necrosis factor (TNF) therapy and evaluate for any serologic and genetic associations. METHODS: This study was a retrospective review of patients attending the inflammatory bowel disease (IBD) centers at Cedars-Sinai IBD Center from 2005-2016. Adverse events were identified via chart review. IBD serologies were measured by ELISA. DNA samples were genotyped at Cedars-Sinai using Illumina Infinium Immunochipv1 array per manufacturer's protocol...
October 28, 2017: World Journal of Gastroenterology: WJG
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