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S Stern, A Mizrachi, Y Strenov, A Knaanie, C Benbassat, T Shpitzer, G Bachar
OBJECTIVE: To investigate the controversial relationship between preoperative calcium and parathyroid hormone levels and the dimensions and histological features of parathyroid adenoma in patients with primary hyperparathyroidism. STUDY DESIGN: Historical cohort. SETTING: Tertiary medical centre. SUBJECTS AND METHODS: Clinical and tumour-related data were collected from the medical files of all patients who underwent parathyroidectomy for primary hyperparathyroidism in 1996-2012...
October 3, 2016: Clinical Otolaryngology
Ahuva Grubstein, Osnat Shtraichman, Elizabeth Fireman, Gil N Bachar, Noa Noach-Ophir, Mordechai R Kramer
OBJECTIVE: The aim of this study was to describe the computed tomography (CT) findings and correlate pulmonary function tests (PFTs) of silicosis patients with emphasis on the findings in lung transplantation (LTX) recipients. METHODS: We studied the chest CT scans from 82 marble workers exposed to artificial stone dust and who had a diagnosis of silicosis, of whom 13 patients underwent LTX. Silicosis-associated findings were graded and correlated to concomitant PFT...
September 27, 2016: Journal of Computer Assisted Tomography
Panagiotis Tsikouras, Zacharoula Koukouli, Nikolaos Psarros, Bachar Manav, Nikolaos Tsagias, Georgios Galazios
OBJECTIVES: The aims of the study were to compare the contraceptive behaviour of Christian and Muslim adolescents who had an abortion in Thrace, Greece, and to examine whether extensive contraceptive counselling at the time of abortion modified their subsequent contraceptive practices. METHODS: Adolescents, aged 14-19 years, who had undergone an elective abortion in our department, were included in a prospective 12-year study. Extensive contraceptive counselling was offered before discharge from the hospital...
September 16, 2016: European Journal of Contraception & Reproductive Health Care
Ohad Hilly, Nir Pillar, Sagit Stern, Yulia Strenov, Gideon Bachar, Noam Shomron, Thomas Shpitzer
Oral cavity squamous cell carcinoma may be more aggressive at presentation and recurrence in young patients compared with older patients. Dysregulation of microRNAs (miRNAs or miRs) has been associated with the development and prognosis of oral cavity cancer. The present study investigated miRNA expression in carcinoma of the oral tongue in young patients. miRNA expression profiles were evaluated in formalin-fixed, paraffin-embedded samples of tumor and normal mucosa from 12 patients aged <30 years old with squamous cell carcinoma of the tongue...
September 2016: Oncology Letters
Emmanouil Angelakis, Muhammad Yasir, Dipankar Bachar, Esam I Azhar, Jean-Christophe Lagier, Fehmida Bibi, Asif A Jiman-Fatani, Maha Alawi, Marwan A Bakarman, Catherine Robert, Didier Raoult
Host genetics, environment, lifestyle and proximity between hosts strongly influence the composition of the gut microbiome. To investigate the association of dietary variables with the gut microbiota, we used 16S rDNA sequencing to test the fecal microbiome of Bedouins and urban Saudis and we compared it to the gut microbiome of baboons living in close contact with Bedouins and eating their leftovers. We also analyzed fermented dairy products commonly consumed by Bedouins in order to investigate their impact on the gut microbiome of this population...
2016: Scientific Reports
Aron Popovtzer, Hanna Burnstein, Salomon Stemmer, Dror Limon, Ohad Hili, Gideon Bachar, Vladamir Sopov, Raphael Feinmesser, David Groshar, Jacob Shvero
BACKGROUND: The optimal treatment for locally advanced laryngeal cancer remains controversial. The purpose of this trial was to determine if the response to induction chemotherapy could select patients for organ preservation protocols, and improve larynx-preservation rates without compromising overall survival (OS). METHODS: The cohort comprised 12 patients with T3 disease and 14 with T4. Induction chemotherapy consisted of docetaxel, cisplatin, and 5-fluorouracil (TPF)...
August 24, 2016: Head & Neck
Grégory Dubourg, Jean-Christophe Lagier, Sophie Hüe, Mathieu Surenaud, Dipankar Bachar, Catherine Robert, Caroline Michelle, Isabelle Ravaux, Saadia Mokhtari, Matthieu Million, Andreas Stein, Philippe Brouqui, Yves Levy, Didier Raoult
OBJECTIVES: Gut microbiota modifications occurring during HIV infection have recently been associated with inflammation and microbial translocation. However, discrepancies between studies justified a comprehensive analysis performed on a large sample size. DESIGN AND METHODS: In a case-control study, next-generation sequencing of the 16S rRNA gene was applied to the faecal microbiota of 31 HIV-infected patients, of whom 18 were treated with antiretroviral treatment (ART), compared with 27 healthy controls...
2016: BMJ Open Gastroenterology
François-Étienne Sylvain, Bachar Cheaib, Martin Llewellyn, Tiago Gabriel Correia, Daniel Barros Fagundes, Adalberto Luis Val, Nicolas Derome
Aquatic organisms are increasingly exposed to lowering of environmental pH due to anthropogenic pressure (e.g. acid rain, acid mine drainages). Such acute variations trigger imbalance of fish-associated microbiota, which in turn favour opportunistic diseases. We used the tambaqui (Colossoma macropomum), an Amazonian fish tolerant to significant pH variation in its natural environment, to assess the response of fish endogenous microbiota to acute short-term acid stress. We exposed 36 specimens of tambaquis to acidic water (pH 4...
2016: Scientific Reports
Anna K Kowalczyk, Bradlee J Bachar, Hong Liu
No abstract text is available yet for this article.
May 2016: Journal of Biomedical Research
Orna Katz, Yuval Nachalon, Ohad Hilly, Thomas Shpitzer, Gideon Bachar, Dror Limon, Aron Popovtzer
BACKGROUND: Treatment for early-stage tongue squamous cell carcinoma (SCC) is usually surgery alone. There is ambiguity regarding the impact of minor adverse features (MAFs) on outcome and the role of postoperative radiotherapy (PORT) in tongue SCC. METHODS: A retrospective analysis was performed on 48 patients diagnosed with tongue SCC treated in our center. Patients with MAFs received adjuvant PORT. Disease outcome in patients with MAFs, and the effect of PORT were analyzed using the Kaplan-Meier method and log-rank test...
August 10, 2016: Head & Neck
Jean-Michel Hougardy, Perrine Revercez, Aline Pourcelet, Bachar El Oumeiri, Judith Racapé, Alain Le Moine, Frédéric Vanden Eynden, Daniel De Backer
BACKGROUND: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication and is associated with the poorest outcomes. Therefore, early prediction of CSA-AKI remains a major issue. Severity scores such as the STS score could estimate the risk of AKI preoperatively. The main objective of this study was to evaluate the risk factors of on-pump CSA-AKI and to assess the performance of the STS score in order to predict CSA-AKI. PATIENTS: We identified 252 patients with on-pump cardiac surgery, and the STS score was defined retrospectively...
June 2, 2016: Acta Chirurgica Belgica
Candice D Jordan, Frederick Korley, Bachar Hamade
No abstract text is available yet for this article.
May 20, 2016: American Journal of Emergency Medicine
Panagiotis Tsikouras, Stefanos Zervoudis, Bachar Manav, Eirini Tomara, George Iatrakis, Constantinos Romanidis, Anastasia Bothou, George Galazios
Purpose: Despite the widespread screening programs, cervical cancer remains the third most common cancer in developing countries. Based on the implementation of cervical screening programs with the referred adoption of improved screening methods in cervical cytology with the knowledge of the important role of the human papilloma virus (HPV) it's incidence is decreased in the developed world. Even if cervical HPV infection is incredibly common, cervical cancer is relatively rare. Depending on the rarity of invasive disease and the improvement of detection of pre-cancerous lesions due to the participation in screening programs, the goal of screening is to detect the cervical lesions early in order to be treated before cancer is developed...
March 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
Dror Lakstein, Ira Bachar, Ronen Debi, Omri Lubovsky, Ornit Cohen, Zachary Tan, Ehud Atoun
PURPOSE: The purpose of this study was to evaluate the use of pre-operative digital templating to minimize complications including limb length discrepancy (LLD), intraoperative fractures and early dislocations in patients with intracapsular femoral neck fractures. METHODS: We retrospectively compared 23 patients undergoing total hip arthroplasty (THA) for intracapsular femoral fractures with pre-operative digital templating and 48 patients without templating. RESULTS: The mean post-operative LLD was significantly lower in patients who had pre-operative templating than in the control group (6...
June 7, 2016: International Orthopaedics
Panagiotis Tsikouras, Marina Dimitraki, Stephanos Zervoudis, Bachar Manav, Anastasios Liberis, Georgios Galazios, Georg F VON Tempelhoff
No abstract text is available yet for this article.
June 2016: Minerva Chirurgica
Ravit Bassal, Eduardo Schejter, Rachel Bachar, Tamar Perri, Jacob Korach, Ariella Jakobson-Setton, Liat Hogen Ben-David, Daniel Cohen, Lital Keinan-Boker
PURPOSE: The aim of the study was to identify risk and protective factors/markers for cervical cancer and cervical intraepithelial neoplasia 3 (CIN3) in Israeli Jewish women in order to settle the discrepancy of low incidence rate of cervical cancer and relatively high incidence rate of CIN3. MATERIALS AND METHODS: We conducted two case control studies, which examined the association between potential risk and protective factors/markers for cervical cancer or CIN3 using self administered detailed questionnaires...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Yael Riahi, Jakob D Wikstrom, Etty Bachar-Wikstrom, Nava Polin, Hava Zucker, Myung-Shik Lee, Wenying Quan, Leena Haataja, Ming Liu, Peter Arvan, Erol Cerasi, Gil Leibowitz
No abstract text is available yet for this article.
May 17, 2016: Diabetologia
Emmanouil Angelakis, Dipankar Bachar, Bernard Henrissat, Fabrice Armougom, Gilles Audoly, Jean-Christophe Lagier, Catherine Robert, Didier Raoult
Exopolysaccharides produced by bacterial species and present in feces are extremely inhibitory to DNA restriction and can cause discrepancies in metagenomic studies. We determined the effects of different DNA extraction methods on the apparent composition of the gut microbiota using Illumina MiSeq deep sequencing technology. DNA was extracted from the stool from an obese female using 10 different methods and the choice of DNA extraction method affected the proportional abundance at the phylum level, species richness (Chao index, 227 to 2,714) and diversity (non parametric Shannon, 1...
2016: Scientific Reports
Matthieu Million, Maryam Tidjani Alou, Saber Khelaifia, Dipankar Bachar, Jean-Christophe Lagier, Niokhor Dione, Souleymane Brah, Perrine Hugon, Vincent Lombard, Fabrice Armougom, Julien Fromonot, Catherine Robert, Caroline Michelle, Aldiouma Diallo, Alexandre Fabre, Régis Guieu, Cheikh Sokhna, Bernard Henrissat, Philippe Parola, Didier Raoult
Severe acute malnutrition (SAM) is associated with inadequate diet, low levels of plasma antioxidants and gut microbiota alterations. The link between gut redox and microbial alterations, however, remains unexplored. By sequencing the gut microbiomes of 79 children of varying nutritional status from three centers in Senegal and Niger, we found a dramatic depletion of obligate anaerobes in malnutrition. This was confirmed in an individual patient data meta-analysis including 107 cases and 77 controls from 5 different African and Asian countries...
2016: Scientific Reports
Liat Honigman, Ofrit Bar-Bachar, David Yarnitsky, Elliot Sprecher, Yelena Granovsky
Compression therapy, a well-recognized treatment for lymphoedema and venous disorders, pressurizes limbs and generates massive non-noxious afferent sensory barrages. The aim of this study was to study whether such afferent activity has an analgesic effect when applied on the lower limbs, hypothesizing that larger compression areas will induce stronger analgesic effects, and whether this effect correlates with conditioned pain modulation (CPM). Thirty young healthy subjects received painful heat and pressure stimuli (47°C for 30 seconds, forearm; 300 kPa for 15 seconds, wrist) before and during 3 compression protocols of either SMALL (up to ankles), MEDIUM (up to knees), or LARGE (up to hips) compression areas...
September 2016: Pain
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