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https://www.readbyqxmd.com/read/28635407/ovarian-reserve-after-fibroid-embolization-in-premenopausal-women
#1
Panagiotis Tsikouras, Bachar Manav, Zacharoula Koukouli, Grigorios Trypsiannis, Georgios Galazios, Dimitrios Souftas, Vasileios Souftas
OBJECTIVE: To investigate the effect of uterine artery embolization (UAE) for fibroids on ovarian pool of premenopausal women. STUDY DESIGN: Prospective case control study. MATERIAL AND METHODS: One-hundred and twenty premenopausal women, aged between 40 and 50 years, who underwent UAE for symptomatic uterine fibroids and the same number of women, aged between 40 and 50 years, with symptomatic uterine fibroids, who were not offered treatment were recruited for this study...
February 24, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28588566/gut-bacteria-missing-in-severe-acute-malnutrition-can-we-identify-potential-probiotics-by-culturomics
#2
Maryam Tidjani Alou, Matthieu Million, Sory I Traore, Donia Mouelhi, Saber Khelaifia, Dipankar Bachar, Aurelia Caputo, Jeremy Delerce, Souleymane Brah, Daouda Alhousseini, Cheikh Sokhna, Catherine Robert, Bouli A Diallo, Aldiouma Diallo, Philippe Parola, Michael Golden, Jean-Christophe Lagier, Didier Raoult
Severe acute malnutrition is the world-leading cause of children under-five's death. Recent metagenomics studies have established a link between gut microbiota and severe acute malnutrition, describing an immaturity with a striking depletion in oxygen-sensitive prokaryotes. Amoxicillin and therapeutic diet cure most of the children with severe acute malnutrition but an irreversible disruption of the gut microbiota is suspected in the refractory and most severe cases. In these cases, therapeutic diet may be unable to reverse the microbiota alteration leading to persistent impaired development or death...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28551923/-extracorporeal-membrane-oxygenation-in-israel-6-5-years-of-experience-at-the-largest-ecmo-treatment-center-in-israel
#3
Philip Biderman, Uri Carmi, Michael Fainblut, Oren Bachar, Benny Medallion, Dan Aravot
AIMS: The primary purpose of the study is to evaluate the characteristics of the population treated with ECMO at Beilinson Hospital, the treatment results and a comparison of results with ECMO centers in the world. The treatment outcomes relative to the experience of the team during the years 2008-2014 were also examined. The secondary purpose of this article is to increase the awareness of the medical staff to ECMO as a treatment option for patients with appropriate indications, where indications have increased in recent years...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28533439/gene-introgression-in-weeds-depends-on-initial-gene-location-in-the-crop-brassica-napus-raphanus-raphanistrum-model
#4
Katarzyna Adamczyk-Chauvat, Sabrina Delaunay, Anne Vannier, Caroline François, Gwenaëlle Thomas, Frédérique Eber, Maryse Lodé, Marie Gilet, Virginie Huteau, Jérôme Morice, Sylvie Nègre, Cyril Falentin, Olivier Coriton, Henri Darmency, Bachar Alrustom, Eric Jenczewski, Mathieu Rousseau-Gueutin, Anne-Marie Chèvre
The effect of gene location within a crop genome on its transfer to a weed genome remains an open question for gene flow assessment. To elucidate this question, we analyzed advanced generations of intergeneric hybrids, derived from an initial pollination of known oilseed rape varieties (Brassica napus, AACC, 2n=38) by a local population of wild radish (Raphanus raphanistrum, RrRr, 2n=18). After five generations of recurrent pollination, 307 G5 plants with a chromosome number similar to wild radish were genotyped using 105 B...
May 22, 2017: Genetics
https://www.readbyqxmd.com/read/28530323/-papillary-thyroid-carcinoma-treatment-is-the-pendulum-shifting
#5
REVIEW
Sagit Stern, Elad Dagan, Eran E Alon, Ziv Gil, Gideon Bachar
The incidence of papillary thyroid carcinoma has been on the rise in the past few decades while the disease specific mortality remains stable. During prophylactic central neck dissection (level 6), an average of 60% positive occult lymph nodes metastasis are found, hence the justification for performing a prophylactic central neck dissection. The opponents for performing neck dissection claim that the disease specific mortality is low regardless of the operation and that adding a neck dissection will, significantly, increase surgical morbidity...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28528858/-percutaneous-nephrolithotomy-pcnl-in-patients-with-chronic-kidney-disease-ckd-efficacy-and-safety
#6
REVIEW
Patrick Jones, Omar M Aboumarzouk, Bachar Zelhof, Moeketsi Mokete, Bhavan Prasad Rai, Bhaskar K Somani
While the effects of percutaneous nephrolithotomy (PCNL) on patients with normal functioning kidneys have been widely studied, the outcomes of PCNL in populations with renal insufficiency remains under reported. We aimed to examine the literature and evaluate the efficacy and safety of PCNL in this non-indexed patient group. A systematic search was performed in accordance with Cochrane guidelines. This served to identify original studies investigating PCNL carried out in the adult population with chronic kidney disease published over the past 20 years (since 1997)...
May 18, 2017: Urology
https://www.readbyqxmd.com/read/28507753/yield-of-magnetic-resonance-cholangiopancreatography-for-the-investigation-of-bile-duct-dilatation-in-asymptomatic-patients
#7
Shlomit Tamir, Marius Braun, Assaf Issachar, Gil N Bachar, Ofer Benjaminov
BACKGROUND: Biliary dilatation in the asymptomatic patient is a frequent incidental finding in the work-up for which there are no current guidelines. OBJECTIVES: The purpose of this study was to determine the yield of magnetic resonance cholangiopancreatography (MRCP) in asymptomatic patients with an incidental finding of biliary duct dilatation. METHODS: The study included 68 consecutive patients for evaluation of biliary duct dilatation found incidentally on computed tomography (CT) or ultrasound (US)...
April 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28365933/preoperative-assessment-in-endometrial-cancer-is-triage-for-lymphadenectomy-possible
#8
Panagiotis Tsikouras, Zacharoula Koukouli, Anastasia Bothou, Bachar Manav, George Iatrakis, Stefanos Zervoudis, George Galazios, Alexander Tobias Teichmann
PURPOSE: We sought to examine whether a preoperative assessment with usual means, available in most hospitals (preoperative histology, pelvic MRI, serum CA-125) can confidently exclude from a full staging surgical procedure low-risk endometrial carcinoma (EC) patients according to ESMO-ESTRO-ESGO criteria (stage I endometrioid EC, grade 1 or 2, myometrial invasion <50% and negative lymphovascular space invasion). METHODS: We retrospectively identified all EC patients that underwent total hysterectomy with bilateral salpingo-oophorectomy (TH-BSO) plus lymph node dissection (LND) as primary treatment for endometrioid tumors from January, 2000 to December, 2010...
January 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28346650/submandibular-salivary-gland-tumors-clinical-course-and-outcome-of-a-20-year-multicenter-study
#9
Aviram Mizrachi, Gideon Bachar, Yaron Unger, Ohad Hilly, Dan M Fliss, Thomas Shpitzer
The purpose of this retrospective chart review study was to review the nature and clinical course of benign and malignant submandibular gland tumors at 2 major university-affiliated tertiary medical centers. All patients who underwent submandibular salivary gland excision between 1990 and 2010 were included. Clinical and disease-related data were collected from the medical charts. One hundred ninety-three patients were identified, of whom 108 (56%) had non-neoplastic disorders (sialolithiasis and sialadenitis)...
March 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28292261/genome-wide-analysis-of-a-avirulent-and-reveal-the-strain-induces-pro-tective-immunity-against-challenge-with-virulent-streptococcus-suis-serotype-2
#10
Jing Wang, Youjun Feng, Changjun Wang, Feng Zheng, Bachar Hassan, Liming Zhi, Wenjuan Li, Yi Yao, Elaine He, Shibo Jiang, Jiaqi Tang
BACKGROUND: It was previously reported in China that two recent large-scale outbreaks of Streptococcus suis serotype 2 (S. suis 2) infections in human were caused by two highly virulent S. suis 2 strains, from which a novel genomic island (GEI), associated with disease onset and progression and designated 89 K, was identified. Here, an avirulent strain, 05HAS68, was isolated from a clinically healthy pig. RESULTS: By comparing the genomes of this avirulent strain with virulent strains, it was found that massive genomic rearrangements occurred, resulting in alterations in gene expression that caused enormous single gene gain and loss...
March 14, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28130395/weight-trajectories-of-israeli-pediatric-cancer-survivors
#11
Marilyn Stern, Eytan Bachar, Eyal Ronen Ackerman, Diana Rancourt, Omer Bonne, Michael Weintraub
Objective: Cross-national replication of the high rates of overweight/obesity among U.S. pediatric cancer survivors (PCS) is limited. Predictors of weight trajectories of Israeli PCS were examined from diagnosis and end of active cancer treatment to 3 years posttreatment. Methods: World Health Organization-derived body mass index (z-BMI) values were calculated at each time point from medical records of 135 Israeli PCS ( M diagnosis age = 11.4). A three-section piecewise multilevel model including age, ethnicity, gender, treatment length, and diagnosis as predictors was used to estimate z-BMI trajectories...
June 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28027285/acute-rhinosinusitis-in-immunosuppressed-children-diagnostic-and-therapeutic-management
#12
Amit Ritter, Salvador Fischer, Eitan Yaniv, Tuvia Hadar, Ethan Soudry, Daniel Shai, Dror Gilony, Gideon Bachar
BACKGROUND: Immunosuppressive therapy places pediatric patients at risk of developing life-threatening sinonasal infections. Diagnosis and treatment are challenging owing to nonspecific signs and symptoms. The aim of this study was to present our department's experience with the surgical management of acute rhinosinusitis in immunosuppressed children. METHODS: The records of all children with a hematologic or oncologic disease who underwent endoscopic sinus surgery (ESS) for acute rhinosinusitis from January 2005 to May 2014 were reviewed...
April 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27884923/clinical-metrics-in-emergency-medicine-the-shock-index-and-the-probability-of-hospital-admission-and-inpatient-mortality
#13
Kamna S Balhara, Yu-Hsiang Hsieh, Bachar Hamade, Ryan Circh, Gabor D Kelen, Jamil D Bayram
STUDY OBJECTIVES: The shock index (SI), defined as the ratio of HR to systolic BP, has been studied as an alternative prognostic tool to traditional vital signs in specific disease states and subgroups of patients. However, literature regarding its utility in the general ED population is lacking. Our main objective was to determine the probability of admission and inpatient mortality based on the first measured SI at initial presentation in the general adult ED population in our tertiary care centre...
February 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/27819657/culture-of-previously-uncultured-members-of-the-human-gut-microbiota-by-culturomics
#14
Jean-Christophe Lagier, Saber Khelaifia, Maryam Tidjani Alou, Sokhna Ndongo, Niokhor Dione, Perrine Hugon, Aurelia Caputo, Frédéric Cadoret, Sory Ibrahima Traore, El Hadji Seck, Gregory Dubourg, Guillaume Durand, Gaël Mourembou, Elodie Guilhot, Amadou Togo, Sara Bellali, Dipankar Bachar, Nadim Cassir, Fadi Bittar, Jérémy Delerce, Morgane Mailhe, Davide Ricaboni, Melhem Bilen, Nicole Prisca Makaya Dangui Nieko, Ndeye Mery Dia Badiane, Camille Valles, Donia Mouelhi, Khoudia Diop, Matthieu Million, Didier Musso, Jônatas Abrahão, Esam Ibraheem Azhar, Fehmida Bibi, Muhammad Yasir, Aldiouma Diallo, Cheikh Sokhna, Felix Djossou, Véronique Vitton, Catherine Robert, Jean Marc Rolain, Bernard La Scola, Pierre-Edouard Fournier, Anthony Levasseur, Didier Raoult
Metagenomics revolutionized the understanding of the relations among the human microbiome, health and diseases, but generated a countless number of sequences that have not been assigned to a known microorganism(1). The pure culture of prokaryotes, neglected in recent decades, remains essential to elucidating the role of these organisms(2). We recently introduced microbial culturomics, a culturing approach that uses multiple culture conditions and matrix-assisted laser desorption/ionization-time of flight and 16S rRNA for identification(2)...
November 7, 2016: Nature Microbiology
https://www.readbyqxmd.com/read/27792831/prognostic-factors-in-metastatic-cutaneous-squamous-cell-carcinoma-of-the-head-and-neck
#15
Gideon Bachar, Aviram Mizrachi, Naomi Rabinovics, Dan Guttman, Thomas Shpitzer, Dean Ad-El, Tuvia Hadar
Metastatic cutaneous squamous cell carcinoma (SCC) of the head and neck poses a significant therapeutic challenge due to its aggressive biologic behavior. We conducted a retrospective study of 71 patients-58 men and 13 women, aged 28 to 88 years (mean: 71)-who had been treated at our university-affiliated tertiary care medical center for metastatic cutaneous SCC over a 15-year period. In addition to demographic data, we compiled and analyzed information on tumor characteristics, the site and extent of metastasis, treatment, follow-up, and outcome...
October 2016: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/27696726/parathyroid-adenoma-a-comprehensive-biochemical-and-histological-correlative-study
#16
S Stern, A Mizrachi, Y Strenov, A Knaanie, C Benbassat, T Shpitzer, G Bachar
OBJECTIVE: To investigate the controversial relationship between preoperative calcium and parathyroid hormone levels and the dimensions and histological features of parathyroid adenoma in patients with primary hyperparathyroidism. STUDY DESIGN: Historical cohort. SETTING: Tertiary medical centre. SUBJECTS AND METHODS: Clinical and tumour-related data were collected from the medical files of all patients who underwent parathyroidectomy for primary hyperparathyroidism in 1996-2012...
October 3, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27680410/radiological-evaluation-of-artificial-stone-silicosis-outbreak-emphasizing-findings-in-lung-transplant-recipients
#17
Ahuva Grubstein, Osnat Shtraichman, Elizabeth Fireman, Gil N Bachar, Noa Noach-Ophir, Mordechai R Kramer
OBJECTIVE: The aim of this study was to describe the computed tomography (CT) findings and correlate pulmonary function tests (PFTs) of silicosis patients with emphasis on the findings in lung transplantation (LTX) recipients. METHODS: We studied the chest CT scans from 82 marble workers exposed to artificial stone dust and who had a diagnosis of silicosis, of whom 13 patients underwent LTX. Silicosis-associated findings were graded and correlated to concomitant PFT...
November 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27636541/contraceptive-behaviour-of-christian-and-muslim-teenagers-at-the-time-of-abortion-and-post-abortion-in-thrace-greece
#18
COMPARATIVE STUDY
Panagiotis Tsikouras, Zacharoula Koukouli, Nikolaos Psarros, Bachar Manav, Nikolaos Tsagias, Georgios Galazios
OBJECTIVES: The aims of the study were to compare the contraceptive behaviour of Christian and Muslim adolescents who had an abortion in Thrace, Greece, and to examine whether extensive contraceptive counselling at the time of abortion modified their subsequent contraceptive practices. METHODS: Adolescents, aged 14-19 years, who had undergone an elective abortion in our department, were included in a prospective 12-year study. Extensive contraceptive counselling was offered before discharge from the hospital...
December 2016: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/27602107/distinctive-pattern-of-let-7-family-micrornas-in-aggressive-carcinoma-of-the-oral-tongue-in-young-patients
#19
Ohad Hilly, Nir Pillar, Sagit Stern, Yulia Strenov, Gideon Bachar, Noam Shomron, Thomas Shpitzer
Oral cavity squamous cell carcinoma may be more aggressive at presentation and recurrence in young patients compared with older patients. Dysregulation of microRNAs (miRNAs or miRs) has been associated with the development and prognosis of oral cavity cancer. The present study investigated miRNA expression in carcinoma of the oral tongue in young patients. miRNA expression profiles were evaluated in formalin-fixed, paraffin-embedded samples of tumor and normal mucosa from 12 patients aged <30 years old with squamous cell carcinoma of the tongue...
September 2016: Oncology Letters
https://www.readbyqxmd.com/read/27578328/gut-microbiome-and-dietary-patterns-in-different-saudi-populations-and-monkeys
#20
Emmanouil Angelakis, Muhammad Yasir, Dipankar Bachar, Esam I Azhar, Jean-Christophe Lagier, Fehmida Bibi, Asif A Jiman-Fatani, Maha Alawi, Marwan A Bakarman, Catherine Robert, Didier Raoult
Host genetics, environment, lifestyle and proximity between hosts strongly influence the composition of the gut microbiome. To investigate the association of dietary variables with the gut microbiota, we used 16S rDNA sequencing to test the fecal microbiome of Bedouins and urban Saudis and we compared it to the gut microbiome of baboons living in close contact with Bedouins and eating their leftovers. We also analyzed fermented dairy products commonly consumed by Bedouins in order to investigate their impact on the gut microbiome of this population...
2016: Scientific Reports
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