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Blood flow restriction

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https://www.readbyqxmd.com/read/28214295/blood-flow-restriction-increases-metabolic-stress-but-decreases-muscle-activation-during-high-load-resistance-exercise
#1
Emerson L Teixeira, Renato Barroso, Carla Silva-Batista, Gilberto C Laurentino, Jeremy P Loenneke, Hamilton Roschel, Carlos Ugrinowitsch, Valmor Tricoli
INTRODUCTION: We investigated differences in metabolic stress (lactate) and muscle activation (electromyography) when high load exercise is compared to a condition where blood flow restriction (BFR) is applied during the exercise or during the rest interval. METHODS: Twelve participants performed high load resistance exercise with BFR during the intervals (BFR-I), during the set (BFR-S) and without BFR (HL). Each condition consisted of 3 sets of 8 repetitions with knee-extension at 70% of one-repetition-maximum...
February 18, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28202441/effect-of-hypohydration-on-postsynaptic-cutaneous-vasodilation-and-sweating-in-healthy-men
#2
Matthew A Tucker, Ashley Six, Nicole E Moyen, Alf Z Satterfield, Matthew S Ganio
: Hypohydration decreases cutaneous vasodilation and sweating during heat stress, but it is unknown if these decrements are from postsynaptic (i.e. sweat gland/blood vessel) alterations. PURPOSE: To determine if hypohydration affects postsynaptic cutaneous vasodilation and sweating responses. METHODS: 12 healthy men participated in euhydrated (EU) and hypohydrated (HY) trials, with hypohydration induced via fluid restriction and passive heat-stress...
February 15, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28183863/hemodynamic-responses-are-reduced-with-aerobic-compared-with-resistance-blood-flow-restriction-exercise
#3
Anthony K May, Christopher R Brandner, Stuart A Warmington
The hemodynamics of light-load exercise with an applied blood-flow restriction (BFR) have not been extensively compared between light-intensity, BFR, and high-intensity forms of both resistance and aerobic exercise in the same participant population. Therefore, the purpose of this study was to use a randomized crossover design to examine the hemodynamic responses to resistance and aerobic BFR exercise in comparison with a common high-intensity and light-intensity non-BFR exercise. On separate occasions participants completed a leg-press (resistance) or treadmill (aerobic) trial...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28179254/a-mathematical-model-of-the-rat-kidney-k-induced-natriuresis
#4
Alan M Weinstein
A model of the rat nephron (Am. J. Physiol. 308:F1098, 2015) has been extended with addition of medullary vasculature. Blood vessels contain solutes from the nephron model, plus additional species from the model of Atherton et al. (Am. J. Physiol. 247:F61, 1984), representing hemoglobin buffering. In contrast to prior models of the urine concentrating mechanism, reflection coefficients for DVR are near zero. Model unknowns are initial proximal tubule pressures and flows, connecting tubule pressure, and medullary interstitial pressures and concentrations...
February 8, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28174436/cardiovascular-response-to-bouts-of-exercise-with-blood-flow-restriction
#5
Kestutis Bunevicius, Arturas Sujeta, Kristina Poderiene, Birute Zachariene, Viktoras Silinskas, Rimantas Minkevicius, Jonas Poderys
[Purpose] Occlusion training with low-intensity resistance exercises and blood flow restriction increases muscle cross-sectional area and strength. This form of training is used in rehabilitation; therefore, the aim of this study was to examine the effect of one occlusion training session on the cardiovascular response to bouts of exercise. [Subjects and Methods] Two groups took part: a control group without blood flow restriction and an experimental group with blood flow restriction. A single training session was used with the exercise intensity set at 40% of the one repetition maximum...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28169942/rbc-transfusion-improves-cerebral-oxygen-delivery-in-subarachnoid-hemorrhage
#6
Rajat Dhar, Allyson R Zazulia, Colin P Derdeyn, Michael N Diringer
OBJECTIVES: Impaired oxygen delivery due to reduced cerebral blood flow is the hallmark of delayed cerebral ischemia following subarachnoid hemorrhage. Since anemia reduces arterial oxygen content, it further threatens oxygen delivery increasing the risk of cerebral infarction. Thus, subarachnoid hemorrhage may constitute an important exception to current restrictive transfusion practices, wherein raising hemoglobin could reduce the risk of ischemia in a critically hypoperfused organ...
February 6, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28157488/placental-stem-villus-arterial-remodeling-associated-with-reduced-hydrogen-sulfide-synthesis-contributes-to-human-fetal-growth-restriction
#7
Liangjian Lu, John Kingdom, Graham J Burton, Tereza Cindrova-Davies
Intrauterine fetal growth restriction (IUGR) is often associated with compromised umbilical arterial flow, indicating increased placental vascular resistance. Oxidative stress is causatively implicated. Hydrogen sulfide maintains differentiated smooth muscle in vascular beds, and its synthetic enzyme cystathionine-γ-lyase (CSE) is down-regulated in growth-restricted placentas. We hypothesized that remodeling of resistance arteries in stem villi contributes to IUGR by compromising umbilical blood flow via oxidative stress, reducing hydrogen sulfide signaling...
February 1, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28144415/acute-cardiovascular-and-hemodynamic-responses-to-low-intensity-eccentric-resistance-exercise-with-blood-flow-restriction
#8
Behzad Bazgir, Mojtaba Rezazadeh Valojerdi, Hamid Rajabi, Rouhollah Fathi, Seyed Mojtaba Ojaghi, Mohammad Kazem Emami Meybodi, Gabriel R Neto, Mostafa Rahimi, Alireza Asgari
BACKGROUND: Recently it has been suggested that low intensity (LI) resistance exercise (RE) alone or in combination with blood flow restriction (BFR) can be applied for cardiovascular function improvement or rehabilitation. OBJECTIVES: The aim of the present study was to investigate the acute effects of LI eccentric RE with and without BFR on heart rate (HR), rate pressure product (RPP), blood pressure (BP) parameters [systolic, diastolic, and mean arterial pressure (MAP)], oxygen saturation (SpO2) and rate of perceived exertion (RPE)...
December 2016: Asian Journal of Sports Medicine
https://www.readbyqxmd.com/read/28143367/does-a-resistance-exercise-session-with-continuous-or-intermittent-blood-flow-restriction-promote-muscle-damage-and-increase-oxidative-stress
#9
Gabriel R Neto, Jefferson S Novaes, Verônica P Salerno, Michel M Gonçalves, Gilmário R Batista, Maria S Cirilo-Sousa
The aim of this study was to compare the effect of low-load resistance exercise (LLRE) with continuous and intermittent blood flow restriction (BFR) on the creatine kinase (CK), lactate dehydrogenase (LDH), protein carbonyl (PC), thiobarbituric acid-reactive substance (TBARS) and uric acid (UA) levels in military men. The study included 10 recreationally trained men aged 19 ± 0.82 years who underwent the following experimental protocols in random order on separate days (72-96 h): 4 LLRE sessions at a 20% 1RM (one-repetition maximum [1RM]) with continuous BFR (LLRE + CBFR); 4 LLRE sessions at 20% 1RM with intermittent BFR (LLRE + IBFR) and 4 high-intensity resistance exercise (HIRE) sessions at 80% 1RM...
January 31, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28143359/the-role-of-blood-flow-restriction-training-for-applied-practitioners-a-questionnaire-based-survey
#10
Stephen D Patterson, Christopher R Brandner
The purpose of the study was to investigate the current use of blood flow restriction (BFR) by practitioners during exercise/training. A questionnaire was developed and data were obtained from 250 participants, with 115 stating that they had prescribed BFR as an intervention. The most common exercise intervention used in combination with BFR was resistance exercise (99/115), followed by during passive (30/115) conditions, and during aerobic exercise (22/115). The main outcome measure for using the technique was to increase muscle mass (32...
February 1, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28131507/the-influence-of-time-on-determining-blood-flow-restriction-pressure
#11
James W Ingram, Scott J Dankel, Samuel L Buckner, Brittany R Counts, J Grant Mouser, Takashi Abe, Gilberto C Laurentino, Jeremy P Loenneke
: The influence of time, manifested in the oscillatory nature of physiology, has been documented in many processes. Within blood flow restriction literature, the restrictive stimulus is often applied based on a single arterial occlusion measurement, which is closely related to brachial systolic blood pressure (bSBP). Considering the oscillatory nature of bSBP, it is likely that time also influences arterial occlusion measurements. OBJECTIVES: To investigate the influence of time, within and between days, on arterial occlusion pressure and to determine whether the variability resembles the oscillatory pattern of bSBP...
January 24, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28127587/corticospinal-excitability-changes-following-blood-flow-restriction-training-of-the-tibialis-anterior-a-preliminary-study
#12
Erhard Trillingsgaard Næss-Schmidt, Morten Morthorst, Asger Roer Pedersen, Jørgen Feldbæk Nielsen, Peter William Stubbs
AIM: To examine the neural excitability of projections to the tibialis anterior (TA) following blood flow restriction training (BFRT). This is the first study to examine the TA following BFRT. METHODS: Ten subjects performed each experiment. Experiment one consisted of BFRT at 130 mmHg (BFRT-low). Experiment two consisted of BFRT at 200 mmHg (BFRT-high), training (TR-only) and blood flow restriction at 200 mmHg (BFR-only) performed on separate days. Blood flow restriction was applied to the thigh and training consisted of rapid dorsiflexion contractions against gravity every 10 s for 15-min...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28126891/2-18f-fluoroethanol-is-a-novel-positron-emission-tomography-pet-reporter-of-solid-tumour-perfusion
#13
Brennan J Wadsworth, Jinhe Pan, Iulia Dude, Nadine Colpo, Momir Bosiljcic, Kuo Shyan Lin, Francois Benard, Kevin L Bennewith
: Solid tumour perfusion is a proven variable of interest for predicting cancer aggression and response to therapy. Current methods for non-invasively imaging tumour perfusion with positron emission tomography (PET) are limited by restricted accessibility and short half-lives of perfusion radiotracers. This study presents 2-(18)F-fluoroethanol (2-(18)F-FEtOH) as a perfusion reporter that can distinguish between tumours of varying perfusion levels and can be applied to screening drugs that modify tumour perfusion...
January 26, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28124127/acute-low-intensity-cycling-with-blood-flow-restriction-has-no-effect-on-metabolic-signaling-in-human-skeletal-muscle-compared-to-traditional-exercise
#14
William J Smiles, Miguel S Conceição, Guilherme D Telles, Mara P T Chacon-Mikahil, Cláudia R Cavaglieri, Felipe C Vechin, Cleiton A Libardi, John A Hawley, Donny M Camera
PURPOSE: Autophagy is an intracellular degradative system sensitive to hypoxia and exercise-induced perturbations to cellular bioenergetics. We determined the effects of low-intensity endurance-based exercise performed with blood-flow restriction (BFR) on cell signaling adaptive responses regulating autophagy and substrate metabolism in human skeletal muscle. METHODS: In a randomized cross-over design, nine young, healthy but physically inactive males completed three experimental trials separated by 1 week of recovery consisting of either a resistance exercise bout (REX: 4 × 10 leg press repetitions, 70% 1-RM), endurance exercise (END: 30 min cycling, 70% VO2peak), or low-intensity cycling with BFR (15 min, 40% VO2peak)...
January 25, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28121802/delayed-effect-of-blood-flow-restricted-resistance-training-on-rapid-force-capacity
#15
Jakob Lindberg Nielsen, Ulrik Frandsen, Tatyana Prokhorova, Rune Dueholm Bech, Tobias Nygaard, Charlotte Suetta, Per Aagaard
PURPOSE: The aim of the present study was to investigate the effect and time course of high-frequent low-load resistance training with blood-flow restriction (BFR) on rapid force capacity (i.e. rate of torque development (RTD)). METHODS: Ten male subjects (22.8±2.3 years) performed four sets of knee extensor exercise (20%1RM) to concentric failure during concurrent BFR of the thigh (100mmHg), while eight work-matched controls (21.9±3.0 years) trained without BFR (CON)...
January 23, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28118308/delayed-onset-muscle-soreness-and-perceived-exertion-following-blood-flow-restriction-exercise
#16
Christopher R Brandner, Stuart A Warmington
The purpose of this study was to determine the perceptual responses to resistance exercise with either heavy-loads (80% 1 repetition maximum [1-RM]), light-loads (20% 1-RM), or light-loads in combination with blood flow restriction (BFR). Despite the use of light-loads, it has been suggested that the adoption of BFR resistance exercise may be limited due to increases in delayed onset muscle soreness (DOMS) and perceived exertion. Seventeen healthy untrained males participated in this balanced, randomized cross-over study...
January 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28114884/everrest-prospective-study-a-6-year-prospective-study-to-define-the-clinical-and-biological-characteristics-of-pregnancies-affected-by-severe-early-onset-fetal-growth-restriction
#17
Rebecca Spencer, Gareth Ambler, Jana Brodszki, Anke Diemert, Francesc Figueras, Eduard Gratacós, Stefan R Hansson, Kurt Hecher, Angela Huertas-Ceballos, Neil Marlow, Karel Marsál, Eva Morsing, Donald Peebles, Carlo Rossi, Neil J Sebire, John F Timms, Anna L David
BACKGROUND: Fetal growth restriction (FGR) is a serious obstetric condition for which there is currently no treatment. The EVERREST Prospective Study has been designed to characterise the natural history of pregnancies affected by severe early onset FGR and establish a well phenotyped bio-bank. The findings will provide up-to-date information for clinicians and patients and inform the design and conduct of the EVERREST Clinical Trial: a phase I/IIa trial to assess the safety and efficacy of maternal vascular endothelial growth factor (VEGF) gene therapy in severe early onset FGR...
January 23, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28114170/humoral-reactivity-of-renal-transplant-waitlisted-patients-to-cells-from-ggta1-cmah-b4galnt2-and-sla-class-i-knockout-pigs
#18
Gregory R Martens, Luz M Reyes, James R Butler, Joseph M Ladowski, Jose L Estrada, Richard A Sidner, Devin E Eckhoff, Matt Tector, A Joseph Tector
BACKGROUND: Anti-pig antibodies are a barrier to clinical xenotransplantation. We evaluated antibody binding of waitlisted renal transplant patients to 3 glycan KO pig cells and Class I swine leukocyte antigens (SLA). METHODS: Peripheral blood mononuclear cells (PBMCs) from SLA identical wild type, GGTA1 KO, GGTA1/CMAH KO, and GGTA1/CMAH/B4GalNT2 KO pigs were screened for human antibody binding using flow cytometric crossmatch (FCXM). Sera from 820 patients were screened on B4GalNT2/CMAH/GGTA1 KO cells and a subset with elevated binding was evaluated further...
January 21, 2017: Transplantation
https://www.readbyqxmd.com/read/28113368/a-comparison-between-compounding-techniques-using-large-beam-steered-plane-wave-imaging-for-blood-vector-velocity-imaging-in-a-carotid-artery-model
#19
Anne Saris, Hendrik Hansen, Stein Fekkes, Maartje Nillesen, Marcel Rutten, Chris de Korte
Conventional color Doppler imaging is limited, since it only provides velocity estimates along the ultrasound beam direction for a restricted field of view at a limited frame rate. High frame rate speckle tracking, using plane wave transmits, has shown potential for 2D blood velocity estimation. However, due to the lack of focusing in transmit, image quality gets reduced, which hampers speckle tracking. Although ultrafast imaging facilitates improved clutter filtering, it still remains a major challenge in blood velocity estimation...
September 7, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28103875/effects-of-plasmodium-falciparum-infection-on-umbilical-artery-resistance-and-intrafetal-blood-flow-distribution-a-doppler-ultrasound-study-from-papua-new-guinea
#20
Maria Ome-Kaius, Stephan Karl, Regina Alice Wangnapi, John Walpe Bolnga, Glen Mola, Jane Walker, Ivo Mueller, Holger Werner Unger, Stephen John Rogerson
BACKGROUND: Doppler velocimetry studies of umbilical artery (UA) and middle cerebral artery (MCA) flow help to determine the presence and severity of fetal growth restriction. Increased UA resistance and reduced MCA pulsatility may indicate increased placental resistance and intrafetal blood flow redistribution. Malaria causes low birth weight and fetal growth restriction, but few studies have assessed its effects on uteroplacental and fetoplacental blood flow. METHODS: Colour-pulsed Doppler ultrasound was used to assess UA and MCA flow in 396 Papua New Guinean singleton fetuses...
January 19, 2017: Malaria Journal
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