keyword
MENU ▼
Read by QxMD icon Read
search

Hpc

keyword
https://www.readbyqxmd.com/read/28940696/the-barcelona-hospital-cl%C3%A3-nic-therapeutic-apheresis-database
#1
Joan Cid, Gloria Carbassé, Marc Cid-Caballero, Yolanda López-Púa, Cristina Alba, Dolores Perea, Miguel Lozano
INTRODUCTION: A therapeutic apheresis (TA) database helps to increase knowledge about indications and type of apheresis procedures that are performed in clinical practice. The objective of the present report was to describe the type and number of TA procedures that were performed at our institution in a 10-year period, from 2007 to 2016. MATERIAL AND METHODS: The TA electronic database was created by transferring patient data from electronic medical records and consultation forms into a Microsoft Access database developed exclusively for this purpose...
September 22, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/28937333/provider-prioritized-domains-of-quality-in-pediatric-home-based-hospice-and-palliative-care-a-study-of-the-ohio-pediatric-palliative-care-and-end-of-life-network
#2
Rachel Thienprayoon, Melissa San Julian Mark, Daniel Grossoehme
BACKGROUND: Children receiving hospice and palliative care (HPC) differ from adults in important ways. Children are more likely to have rare diagnoses, less likely to have cancer, have longer lengths of stay on hospice, and are more likely to be technology dependent than adults. The National Consensus Project (NCP) in Palliative Care established domains of quality for HPC, but these domains have not been evaluated for applicability in children. OBJECTIVES: This study aims to establish consensus stakeholder-prioritized domains of high-quality pediatric home-based hospice and palliative care (HBHPC)...
September 22, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28930454/chemical-bypass-of-general-base-catalysis-in-hedgehog-protein-cholesterolysis-using-a-hyper-nucleophilic-substrate
#3
Daniel Ciulla, Michael Jorgensen, Jose-Luis Giner, Brian P Callahan
Proteins in the hedgehog family undergo self-catalyzed endoproteolysis involving nucleophilic attack by a molecule of cholesterol. Recently, a conserved aspartate residue (D303, or D46) of hedgehog was identified as the general base that activates cholesterol during this unusual autoprocessing event; mutation of the catalyzing functional group (D303A) reduces activity by >104 fold. Here we report near total rescue of this ostensibly dead general base mutant by a synthetic substrate, 3ß-hydroperoxycholestane (3HPC) in which the sterol -OH group is replaced by the hyper nucleophilic -OOH group...
September 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28927749/transcriptome-analysis-uncovers-a-growth-promoting-activity-of-orosomucoid-1-on-hepatocytes
#4
Xian-Yang Qin, Mitsuko Hara, Erik Arner, Yoshikuni Kawaguchi, Ikuyo Inoue, Hideki Tatsukawa, Yutaka Furutani, Keisuke Nagatsuma, Tomokazu Matsuura, Feifei Wei, Jun Kikuchi, Hideko Sone, Carsten Daub, Hideya Kawaji, Timo Lassmann, Masayoshi Itoh, Harukazu Suzuki, Piero Carninci, Yoshihide Hayashizaki, Norihiro Kokudo, Alistair R R Forrest, Soichi Kojima
The acute phase protein orosomucoid-1 (Orm1) is mainly expressed by hepatocytes (HPCs) under stress conditions. However, its specific function is not fully understood. Here, we report a role of Orm1 as an executer of HPC proliferation. Increases in serum levels of Orm1 were observed in patients after surgical resection for liver cancer and in mice undergone partial hepatectomy (PH). Transcriptome study showed that Orm1 became the most abundant in HPCs isolated from regenerating mouse liver tissues after PH...
September 12, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28916503/altered-serotonergic-and-gabaergic-neurotransmission-in-a-mice-model-of-obsessive-compulsive-disorder
#5
Christine Winter, Dana M Greene, Paraskevi Mavrogiorgou, Helge Schaper, Reinhard Sohr, Abel Bult-Ito, Georg Juckel
There is ample evidence that obsessive-compulsive disorder (OCD) is based on reduced serotonergic function. Replicated bidirectional selection for thermoregulatory nest-building behavior in the laboratory house mouse (Mus musculus) resulted in compulsive-like, non-compulsive-like and randomly bred control mice that represent a non-induced animal model of OCD. The present study aimed at investigating the neurochemical patterns in specific brain regions of compulsive-like (HA) versus non-compulsive-like (LA) and normal (CA) mice...
September 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28916372/tracking-and-controlling-soft-surface-contamination-in-health-care-settings
#6
Jonathan D Sexton, Amanda M Wilson, Hannah P Sassi, Kelly A Reynolds
BACKGROUND: Study objectives were to track the transfer of microbes on soft surfaces in health care environments and determine the efficiency of an Environmental Protection Agency (EPA)-registered soft surface sanitizer in the health care environment. METHODS: Soft surfaces at 3 health care facilities were sampled for heterotrophic plate count (HPC) bacteria, Staphylococcus spp, Streptococcus pyogenes, and Escherichia coli followed by a tracer study with a virus surrogate seeded onto volunteer hands and commonly touched surfaces...
September 12, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28914524/templated-and-catalytic-fabrication-of-n-doped-hierarchical-porous-carbon-carbon-nanotubes-hybrids-as-host-for-lithium-sulfur-batteries
#7
Junjie Cai, Chun Wu, Shaoran Yang, Ying Zhu, Pei Kang Shen, Kaili Zhang
Nitrogen-doped hierarchical porous carbon and carbon nanotube hybrids (N-HPC-CNTs) are fabricated by simple pyrolysis of the N-rich raw material melamine-formaldehyde (MF) resin in the presence of nano-CaCO3 and bimetallic combination of Fe-Co catalyst. During carbonization, nano-CaCO3 acts as template for creating a hierarchical porous carbon and the N atoms originated from MF resin are in-situ doped into the carbon matrix simultaneously. Meanwhile, volatile gases generated by the thermal decomposition of MF resin could serve as carbon and nitrogen sources to grow nitrogen doped CNTs on HPC...
September 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28913848/effect-of-the-duration-of-hospice-and-palliative-care-on-the-quality-of-dying-and-death-in-patients-with-terminal-cancer-a-nationwide-multicentre-study
#8
J Y Choi, K A Kong, Y J Chang, H J Jho, E M Ahn, S K Choi, S Park, M K Lee
Early referral to hospice and palliative care (HPC) has significant benefits, but little is known about the appropriate time for referral. The purpose of this study of terminal cancer patients was to identify the most appropriate time for referral to HPC. Cross-sectional correlation study design was used. Participants were the bereaved relatives, who were the adult primary caregivers of the 1,829 terminal cancer patients who died 2-6 months previously in nationwide centres that provide HPC in Korea. A post-bereavement survey (Good Death Inventory, GDI) of family caregivers was used to assess patients' quality of dying and death...
September 15, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28912659/power-time-curve-comparison-between-weightlifting-derivatives
#9
Timothy J Suchomel, Christopher J Sole
This study examined the power production differences between weightlifting derivatives through a comparison of power-time (P-t) curves. Thirteen resistance-trained males performed hang power clean (HPC), jump shrug (JS), and hang high pull (HHP) repetitions at relative loads of 30%, 45%, 65%, and 80% of their one repetition maximum (1RM) HPC. Relative peak power (PPRel), work (WRel), and P-t curves were compared. The JS produced greater PPRel than the HPC (p < 0.001, d = 2.53) and the HHP (p < 0.001, d = 2...
September 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28910385/improving-the-characterization-of-endothelial-progenitor-cell-subsets-by-an-optimized-facs-protocol
#10
Karin Huizer, Dana A M Mustafa, J Clarissa Spelt, Johan M Kros, Andrea Sacchetti
The characterization of circulating endothelial progenitor cells (EPCs) is fundamental to any study related to angiogenesis. Unfortunately, current literature lacks consistency in the definition of EPC subsets due to variations in isolation strategies and inconsistencies in the use of lineage markers. Here we address critical points in the identification of hematopoietic progenitor cells (HPCs), circulating endothelial cells (CECs), and culture-generated outgrowth endothelial cells (OECs) from blood samples of healthy adults (AB) and umbilical cord (UCB)...
2017: PloS One
https://www.readbyqxmd.com/read/28902225/optical-tracking-of-relaxation-dynamics-in-semi-dilute-hydroxypropylcellulose-solutions-as-a-precise-phase-transition-probe
#11
Hernan Garate, King-Wo Li, Denis Bouyer, Patrick Guenoun
Phase separation of thermo-responsive polymers in solution is a complex process, whose understanding is essential to screen and design materials with diverse technological applications. Here we report on a method based on dynamic light scattering (DLS) experiments to investigate the phase separation of thermo-responsive polymer solutions and precisely define the transition temperature (TPS). Our results are applied on hydroxypropylcellulose (HPC) solutions as an important biosourced green water-soluble polymer...
September 13, 2017: Soft Matter
https://www.readbyqxmd.com/read/28901620/assessment-of-the-spectral-performance-of-hybrid-photon-counting-x-ray-detectors
#12
Peter Trueb, Pietro Zambon, Christian Broennimann
PURPOSE: Hybrid Photon Counting (HPC) detectors profoundly improved x-ray diffraction experiments at third generation synchrotron facilities. Enabling the simultaneous measurement of x-ray intensities in multiple energy bins, they also have many potential applications in the field of medical imaging. A prerequisite for this is a clean spectral response. To quantify how efficiently HPC detectors are able to assign photons to the correct energy bin, a quantity called Spectral Efficiency (SE) is introduced...
September 2017: Medical Physics
https://www.readbyqxmd.com/read/28901489/uplc%C3%A2-qtofms%C3%A2-based-metabolomic-analysis-of-the-serum-of-hypoxic-preconditioning-mice
#13
Jie Liu, Gang Zhan, Dewei Chen, Jian Chen, Zhi-Bin Yuan, Er-Long Zhang, Yi-Xing Gao, Gang Xu, Bing-Da Sun, Wenting Liao, Yu-Qi Gao
Hypoxic preconditioning (HPC) is well‑known to exert a protective effect against hypoxic injury; however, the underlying molecular mechanism remains unclear. The present study utilized a serum metabolomics approach to detect the alterations associated with HPC. In the present study, an animal model of HPC was established by exposing adult BALB/c mice to acute repetitive hypoxia four times. The serum samples were collected by orbital blood sampling. Metabolite profiling was performed using ultra‑performance liquid chromatography‑quadrupole time‑of‑flight mass spectrometry (UPLC‑QTOFMS), in conjunction with univariate and multivariate statistical analyses...
September 13, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28899609/constructing-experience-event-models-from-perception-to-action
#14
REVIEW
Lauren L Richmond, Jeffrey M Zacks
Mental representations of everyday experience are rich, structured, and multimodal. In this article we consider the adaptive pressures that led to human construction of such representations, arguing that structured event representations enable cognitive systems to more effectively predict the trajectory of naturalistic everyday activity. We propose an account of how cortical systems and the hippocampus (HPC) interact to construct, maintain, and update event representations. This analysis throws light on recent research on story comprehension, event segmentation, episodic memory, and action planning...
September 9, 2017: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/28898323/-pontocerebellar-hypoplasia-secondary-to-cask-gene-deletion-case-report
#15
Lucía Rivas, Óscar Blanco, Cristina Torreira, Alfredo Repáraz, Cristina Melcón, Alfonso Amado
INTRODUCTION: Pontocerebellar hypoplasia (PCH) is a reduction of the size of the cerebellum and pons secondary to an alteration in its development, and can be caused by neurodegenerative diseases of genetic origin, of which there are known 10 subtypes (PCH 1-10), cortical malformations, metabolic and genetic diseases. OBJECTIVE: To present the case of a child with microcephaly, PCH and West syndrome, in which the genetic study allowed to make the diagnosis of a deletion on chromosome X...
2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28893953/fate-decision-between-group-3-innate-lymphoid-and-conventional-nk-cell-lineages-by-notch-signaling-in-human-circulating-hematopoietic-progenitors
#16
Seishi Kyoizumi, Yoshiko Kubo, Junko Kajimura, Kengo Yoshida, Tomonori Hayashi, Kei Nakachi, Malcolm A Moore, Marcel R M van den Brink, Yoichiro Kusunoki
The role of Notch signaling in human innate lymphoid cell (ILC) differentiation is unclear, although IL-7 and IL-15 promote differentiation of natural cytotoxicity receptor (NCR) NKp44(+) group 3 ILCs (NCR(+)ILC3s) and conventional NK (cNK) cells from CD34(+) hematopoietic progenitor cells (HPCs) ex vivo. In this study, we analyzed the functions of Notch in the differentiation of NCR(+)ILC3s and cNK cells from human HPC subpopulations circulating in peripheral blood by limiting dilution and clonal assays using high-throughput flow cytometry...
September 11, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28890670/a-phenomenological-and-dynamic-view-of-homology-homologs-as-persistently-reproducible-modules
#17
Daichi G Suzuki, Senji Tanaka
Homology is a fundamental concept in biology. However, the metaphysical status of homology, especially whether a homolog is a part of an individual or a member of a natural kind, is still a matter of intense debate. The proponents of the individuality view of homology criticize the natural kind view of homology by pointing out that homologs are subject to evolutionary transformation, and natural kinds do not change in the evolutionary process. Conversely, some proponents of the natural kind view of homology argue that a homolog can be construed both as a part of an individual and a member of a natural kind...
2017: Biological Theory
https://www.readbyqxmd.com/read/28887890/optimization-of-capillary-zone-electrophoresis-for-charge-heterogeneity-testing-of-biopharmaceuticals-using-enhanced-method-development-principles
#18
B Moritz, V Locatelli, Michele Niess, Andrea Bathke, Steffen Kiessig, Barbara Entler, C Finkler, H Wegele, Jan Stracke
Capillary zone electrophoresis is a well-established technique for charge heterogeneity testing of biopharmaceuticals 1. It is based on the differences between the ratios of net charge and hydrodynamic radius. In an extensive intercompany study, it was recently shown that capillary zone electrophoresis is very robust and can be easily implemented in labs that did not perform it before 2. However, individual characteristics of some examined proteins resulted in suboptimal resolution. Therefore, enhanced method development principles where applied here to investigate possibilities for further method optimization...
September 9, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28883909/computing-platforms-for-big-biological-data-analytics-perspectives-and-challenges
#19
REVIEW
Zekun Yin, Haidong Lan, Guangming Tan, Mian Lu, Athanasios V Vasilakos, Weiguo Liu
The last decade has witnessed an explosion in the amount of available biological sequence data, due to the rapid progress of high-throughput sequencing projects. However, the biological data amount is becoming so great that traditional data analysis platforms and methods can no longer meet the need to rapidly perform data analysis tasks in life sciences. As a result, both biologists and computer scientists are facing the challenge of gaining a profound insight into the deepest biological functions from big biological data...
2017: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/28878149/biomass-waste-inspired-highly-porous-carbon-for-high-performance-lithium-sulfur-batteries
#20
Yan Zhao, Jun Ren, Taizhe Tan, Moulay-Rachid Babaa, Zhumabay Bakenov, Ning Liu, Yongguang Zhang
The synthesis of highly porous carbon (HPC) materials from poplar catkin by KOH chemical activation and hydrothermal carbonization as a conductive additive to a lithium-sulfur cathode is reported. Elemental sulfur was composited with as-prepared HPC through a melt diffusion method to form a S/HPC nanocomposite. Structure and morphology characterization revealed a hierarchically sponge-like structure of HPC with high pore volume (0.62 cm³∙g (−1) ) and large specific surface area (1261.7 m²∙g (−1) )...
September 6, 2017: Nanomaterials
keyword
keyword
25645
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"