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https://www.readbyqxmd.com/read/28431187/feasibility-of-audio-computer-assisted-self-interviewing-with-color-coding-and-helper-assistance-acasi-h-for-hmong-older-adults
#1
Maichou Lor, Barbara J Bowers
Many older adult immigrants in the US, including Hmong older adults, have limited English proficiency (LEP), and cannot read or have difficulty reading even in their first language (non-literate [NL]). Little has been done to identify feasible data collection approaches to enable inclusion of LEP or NL populations in research, limiting knowledge about their health. This study's purpose was to test the feasibility of culturally and linguistically adapted audio computer-assisted self-interviewing (ACASI) with color-labeled response categories and helper assistance (ACASI-H) for collection of health data with Hmong older adults...
April 21, 2017: Research in Nursing & Health
https://www.readbyqxmd.com/read/28430553/sport-concussion-management-using-facebook-a-feasibility-study-of-an-innovative-adjunct-icon
#2
Osman Hassan Ahmed, Anthony G Schneiders, Paul R McCrory, S John Sullivan
CONTEXT:   Sport concussion is currently the focus of much international attention. Innovative methods to assist athletic trainers in facilitating management after this injury need to be investigated. OBJECTIVE:   To investigate the feasibility of using a Facebook concussion-management program termed iCon (interactive concussion management) to facilitate the safe return to play (RTP) of young persons after sport concussion. DESIGN:   Observational study...
April 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28430019/characterization-of-rph24-a-gene-conferring-adult-plant-resistance-to-puccinia-hordei-in-barley
#3
Laura A Ziems, Lee T Hickey, Gregory J Platz, Jerome D Franckowiak, Peter M Dracatos, Davinder Singh, Robert F Park
We identified Rph24 as a locus in barley (Hordeum vulgare L.) controlling adult plant resistance (APR) to leaf rust, caused by Puccinia hordei. The locus was previously reported as a quantitative trait locus in barley line ND24260-1 and named qRphND. We crossed ND24260-1 to the leaf-rust-susceptible standard Gus and determined inheritance patterns in the progeny. For the comparative marker frequency analysis (MFA), resistant and susceptible tails of the F2 were genotyped with Diversity Arrays Technology genotyping-by-sequencing (DArT-Seq) markers...
April 21, 2017: Phytopathology
https://www.readbyqxmd.com/read/28429025/nanoscale-controlled-li-insertion-reaction-induced-by-scanning-electron-beam-irradiation-in-a-li4ti5o12-electrode-material-for-lithium-ion-batteries
#4
Mitsunori Kitta, Masanori Kohyama
The development of a nanoscale battery reaction in an electrode material associated with in situ microscopic observation is significant to an understanding of the solid-state mechanism of a battery reaction. With a Li4Ti5O12 (LTO) crystal as the negative electrode of a Li-ion battery (LIB), we show that a nanoscale-controlled Li-insertion reaction can be produced by electron beam irradiation with scanning transmission electron microscopy (STEM). A selected area in a Li2O-coated thin LTO crystal was irradiated by the electron probe of STEM with a high beam intensity of 2...
April 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28428944/the-status-of-assisted-reproductive-technology-in-korea-in-2012
#5
Gyoung Hoon Lee, Hyun Jin Song, Young Min Choi, Hyuck Dong Han
OBJECTIVE: This study was designed to report the status of assisted reproductive technology (ART) therapy in South Korea between January 1, 2012 and December 31, 2012. METHODS: A localized online survey, originally developed by the International Committee Monitoring Assisted Reproductive Technologies, was first launched and provided to all available ART centers via email in 2015. Fresh embryo transfer (FET) cases were categorized as standard in vitro fertilization, intracytoplasmic sperm injection (ICSI), or half-ICSI...
March 2017: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28428825/comprehensive-evaluation-of-genome-wide-5-hydroxymethylcytosine-profiling-approaches-in-human-dna
#6
Ksenia Skvortsova, Elena Zotenko, Phuc-Loi Luu, Cathryn M Gould, Shalima S Nair, Susan J Clark, Clare Stirzaker
BACKGROUND: The discovery that 5-methylcytosine (5mC) can be oxidized to 5-hydroxymethylcytosine (5hmC) by the ten-eleven translocation (TET) proteins has prompted wide interest in the potential role of 5hmC in reshaping the mammalian DNA methylation landscape. The gold-standard bisulphite conversion technologies to study DNA methylation do not distinguish between 5mC and 5hmC. However, new approaches to mapping 5hmC genome-wide have advanced rapidly, although it is unclear how the different methods compare in accurately calling 5hmC...
2017: Epigenetics & Chromatin
https://www.readbyqxmd.com/read/28428167/developing-a-patient-centered-mhealth-app-a-tool-for-adolescents-with-type-1-diabetes-and-their-parents
#7
Bree E Holtz, Katharine M Murray, Denise D Hershey, Julie K Dunneback, Shelia R Cotten, Amanda J Holmstrom, Arpita Vyas, Molly K Kaiser, Michael A Wood
BACKGROUND: Type 1 diabetes (T1D) afflicts approximately 154,000 people under 20 years of age. Three-quarters of adolescents are not achieving glycosylated hemoglobin (HbA1c) targets, which leads to negative health outcomes. Mobile health (mHealth), the use of technology in health, has been used successfully to improve health in many chronic conditions, including diabetes. OBJECTIVE: The purpose of this study was to use patient-centered research methods to inform and improve the design and functionality of our T1D app, MyT1DHero, and to provide insight for others who are designing a health app for adolescents and parents...
April 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28427796/molecular-methods-for-septicemia-diagnosis
#8
Francesc Marco
Septicemia remains a major cause of hospital mortality. Blood culture remains the best approach to identify the etiological microorganisms when a bloodstream infection is suspected but it takes long time because it relies on bacterial or fungal growth. The introduction in clinical microbiology laboratories of the matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology, DNA hybridization, microarrays or rapid PCR-based test significantly reduce the time to results. Tests for direct detection in whole blood samples are highly desirable because of their potential to identify bloodstream pathogens without waiting for blood cultures to become positive...
April 17, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28426080/c-reactive-protein-and-interleukin-6-microfluidic-immunoassays-with-on-chip-pre-stored-reagents-and-centrifugo-pneumatic-liquid-control
#9
Y Zhao, G Czilwik, V Klein, K Mitsakakis, R Zengerle, N Paust
We present a fully automated centrifugal microfluidic method for particle based protein immunoassays. Stick-pack technology is employed for pre-storage and release of liquid reagents. Quantitative layout of centrifugo-pneumatic particle handling, including timed valving, switching and pumping is assisted by network simulations. The automation is exclusively controlled by the spinning frequency and does not require any additional means. New centrifugal microfluidic process chains are developed in order to sequentially supply wash buffer based on frequency dependent stick-pack opening and pneumatic pumping to perform two washing steps from one stored wash buffer; pre-store and re-suspend functionalized microparticles on a disk; and switch between the path of the waste fluid and the path of the substrate reaction product with 100% efficiency...
April 20, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28425063/blastocyst-derived-stem-cell-populations-under-stress-impact-of-nutrition-and-metabolism-on-stem-cell-potency-loss-and-miscarriage
#10
REVIEW
Yu Yang, Alan Bolnick, Alexandra Shamir, Mohammed Abdulhasan, Quanwen Li, G C Parker, Elizabeth E Puscheck, D A Rappolee
Data from in vitro and in vivo models suggest that malnutrition and stress trigger adaptive responses, leading to small for gestational age (SGA) blastocysts with fewer cell numbers. These stress responses are initially adaptive, but become maladaptive with increasing stress exposures. The common stress responses of the blastocyst-derived stem cells, pluripotent embryonic and multipotent placental trophoblast stem cells (ESCs and TSCs), are decreased growth and potency, and increased, imbalanced and irreversible differentiation...
April 19, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28424922/assistive-technology-for-ultrasound-guided-central-venous-catheter-placement
#11
REVIEW
Mohammad Ikhsan, Kok Kiong Tan, Andi Sudjana Putra
This study evaluated the existing technology used to improve the safety and ease of ultrasound-guided central venous catheterization. Electronic database searches were conducted in Scopus, IEEE, Google Patents, and relevant conference databases (SPIE, MICCAI, and IEEE conferences) for related articles on assistive technology for ultrasound-guided central venous catheterization. A total of 89 articles were examined and pointed to several fields that are currently the focus of improvements to ultrasound-guided procedures...
April 19, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28424471/human-luteinizing-hormone-and-chorionic-gonadotropin-display-biased-agonism-at-the-lh-and-lh-cg-receptors
#12
Laura Riccetti, Romain Yvinec, Danièle Klett, Nathalie Gallay, Yves Combarnous, Eric Reiter, Manuela Simoni, Livio Casarini, Mohammed Akli Ayoub
Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) have been considered biologically equivalent because of their structural similarities and their binding to the same receptor; the LH/CGR. However, accumulating evidence suggest that LH/CGR differentially responds to the two hormones triggering differential intracellular signaling and steroidogenesis. The mechanistic basis of such differential responses remains mostly unknown. Here, we compared the abilities of recombinant rhLH and rhCG to elicit cAMP, β-arrestin 2 activation, and steroidogenesis in HEK293 cells and mouse Leydig tumor cells (mLTC-1)...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424278/detection-of-hpv-subtypes-by-mass-spectrometry-in-ffpe-tissue-specimens-a-reliable-tool-for-routine-diagnostics
#13
Mark Kriegsmann, Petra Wandernoth, Katharina Lisenko, Rita Casadonte, Rémi Longuespée, Norbert Arens, Jörg Kriegsmann
AIMS: Human papilloma virus (HPV) infection is a causative agent for approximately 5% of all new cancer cases in humans. The virus is detected in cervical, anal, vaginal, penile, vulvar and head and neck cancers and has prognostic implications. Thus, test systems are required to detect high-risk but also low-risk HPV subtypes with high specificity and sensitivity in a time-effective and cost-effective manner. In the present study we developed a new mass spectrometry (MS)-based test system for the detection of HPV infections in formalin-fixed paraffin-embedded (FFPE) tissue samples...
May 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28424068/efficacy-of-a-transdiagnostic-internet-based-treatment-for-emotional-disorders-with-a-specific-component-to-address-positive-affect-study-protocol-for-a-randomized-controlled-trial
#14
Amanda Díaz-García, Alberto González-Robles, Javier Fernández-Álvarez, Azucena García-Palacios, Rosa María Baños, Cristina Botella
BACKGROUND: Emotional disorders (ED) are among the most prevalent mental disorders. However, less than 50% of people suffering from ED receive the appropriate treatment. This situation has led to the development of new intervention proposals based on the transdiagnostic perspective, which tries to address the underlying processes common to ED. Most of these programs focus primarily on down-regulating negative affectivity, rather than increasing strengths and up-regulating positive affectivity...
April 20, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28423963/patient-perceptions-of-environmental-control-units-experiences-of-veterans-with-spinal-cord-injuries-and-disorders-receiving-inpatient-va-healthcare
#15
Bella Etingen, Rachael N Martinez, Marissa A Vallette, Ryan Dendinger, Balmatee Bidassie, Scott Miskevics, Hira T Khan, Huberta T Cozart, Sara M Locatelli, Frances M Weaver
PURPOSE: To assess patients' perceptions of environmental control units (ECUs) at Veterans Affairs Spinal Cord Injury Centers. MATERIALS AND METHODS: A brief questionnaire was conducted with patients in real-time while they were hospitalised ("on-the-spot questionnaire"); a survey was mailed to patients who had recently been discharged from a hospital stay ("discharge survey"). Data were analysed using descriptive statistics. RESULTS: Seventy on-the-spot questionnaires and 80 discharge surveys were collected...
April 19, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28423861/a-digital-framework-to-support-providers-and-patients-in-diabetes-related-behavior-modification
#16
Samina Abidi, Michael Vallis, Helena Piccinini-Vallis, Syed Ali Imran, Syed Sibte Raza Abidi
We present Diabetes Web-Centric Information and Support Environment (D-WISE) that features: (a) Decision support tool to assist family physicians to administer Behavior Modification (BM) strategies to patients; and (b) Patient BM application that offers BM strategies and motivational interventions to engage patients. We take a knowledge management approach, using semantic web technologies, to model the social cognition theory constructs, Canadian diabetes guidelines and BM protocols used locally, in terms of a BM ontology that drives the BM decision support to physicians and BM strategy adherence monitoring and messaging to patients...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28423852/using-the-mrc-framework-for-complex-interventions-to-develop-clinical-decision-support-a-case-study
#17
Dawn Dowding, Valentina Lichtner, S José Closs
The Medical Research Council (MRC) framework for complex interventions provides useful guidance to assist with the development and evaluation of health technology interventions such as decision support. In this paper we briefly summarise a project that focused on designing a decision support intervention to assist with the recognition, assessment and management of pain in patients with dementia in an acute hospital setting. We reflect on our experience of using the MRC framework to guide our study design, and highlight the importance of considering decision support interventions as complex interventions...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28423763/learning-healthcare-system-for-the-prescription-of-genetic-testing-in-the-gynecological-cancer-risk
#18
Cristina Suárez-Mejías, Alicia Martínez-García, María Ángeles Martínez-Maestre, José Manuel Silvan-Alfaro, Jesús Moreno Conde, Carlos Luis Parra-Calderón
Clinical evidence demonstrates that BRCA 1 and BRCA2 mutations can develop a gynecological cancer but genetic testing has a high cost to the healthcare system. Besides, several studies in the literature indicate that performing these genetic tests to the population is not cost-efficient. Currently, our physicians do not have a system to provide them the support for prescribing genetic tests. A Decision Support System for prescribing these genetic tests in BRCA1 and BRCA2 and preventing gynecological cancer risks has been designed, developed and deployed in the Virgen del Rocío University Hospital (VRUH)...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28423749/monitoring-activities-related-to-medication-adherence-in-ambient-assisted-living-environments
#19
Patrice C Roy, Samina Raza Abidi, Syed Sibte Raza Abidi
A recent trend in healthcare is to motivate patients to self-manage their health conditions in home-based settings. Medication adherence is an important aspect in disease self-management since sub-optimal medication adherence by the patient can lead to serious healthcare costs and discomfort for the patient. In order to alleviate the limitations of self-reported medication adherence, we can use ambient assistive living (AAL) technologies in smart environments. Activity recognition services allow to retrieve self-management information related to medication adherence in a less intrusive way...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28422134/genetic-structure-and-signatures-of-selection-in-grey-reef-sharks-carcharhinus-amblyrhynchos
#20
P Momigliano, R Harcourt, W D Robbins, V Jaiteh, G N Mahardika, A Sembiring, A Stow
With overfishing reducing the abundance of marine predators in multiple marine ecosystems, knowledge of genetic structure and local adaptation may provide valuable information to assist sustainable management. Despite recent technological advances, most studies on sharks have used small sets of neutral markers to describe their genetic structure. We used 5517 nuclear single-nucleotide polymorphisms (SNPs) and a mitochondrial DNA (mtDNA) gene to characterize patterns of genetic structure and detect signatures of selection in grey reef sharks (Carcharhinus amblyrhynchos)...
April 19, 2017: Heredity
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