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https://www.readbyqxmd.com/read/29777292/transpopliteal-access-for-intraoperative-spinal-angiography-with-combined-percutaneous-treatment-of-spinal-hemangioma
#1
Sudhakar R Satti, Dharti Dua, Ansar Z Vance
No abstract text is available yet for this article.
May 18, 2018: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29777015/a-patient-with-hemodialysis-access-problems
#2
Vandana Dua Niyyar, Charmaine E Lok
No abstract text is available yet for this article.
May 18, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29772444/functional-relevance-of-satb1-in-immune-regulation-and-tumorigenesis
#3
REVIEW
Krishna P Sunkara, Gaurav Gupta, Philip M Hansbro, Kamal Dua, Mary Bebawy
The Special AT-rich Sequence Binding Protein 1 (SATB1) is a chromatin organiser and transcription factor which regulates numerous cellular processes such as differentiation, proliferation and apoptosis through effects on gene expression. SATB1 undergoes various post-translational modifications, which determine its interaction with co-activators and co-repressors to induce regulation of gene transcription. SATB1 is an identified oncogene, its increased expression is associated with poor prognosis in many cancers...
May 14, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29743859/recent-updates-on-neuropharmacological-effects-of-luteolin
#4
Gaurav Gupta, Juhi Tiwari, Rajiv Dahiya, Rakesh Kumar Sharma, Anurag Mishra, Kamal Dua
No abstract text is available yet for this article.
2018: EXCLI Journal
https://www.readbyqxmd.com/read/29739423/isupport-an-online-training-and-support-program-for-caregivers-of-people-with-dementia-study-protocol-for-a-randomized-controlled-trial-in-india
#5
Kala M Mehta, Dolores Gallagher-Thompson, Mathew Varghese, Santosh Loganathan, Upasana Baruah, Katrin Seeher, Diana Zandi, Tarun Dua, Anne Margriet Pot
BACKGROUND: Dementia has a huge physical, psychological, social and economic impact upon caregivers, families and societies at large. There has been a growing impetus to utilize Internet interventions given the potential scalability, and presumed cost-effectiveness and accessibility. In this paper, we describe the design of a randomized controlled trial (RCT) aiming to study the impact of online self-help programs on caregivers of people with dementia in India. The experimental group will receive an interactive training and support program and the comparison group will receive an education-only e-book...
May 8, 2018: Trials
https://www.readbyqxmd.com/read/29736062/dropout-rates-and-factors-associated-with-dropout-from-treatment-among-elderly-patients-attending-the-outpatient-services-of-a-tertiary-care-hospital
#6
Sandeep Grover, Devakshi Dua, Subho Chakrabarti, Ajit Avasthi
Aim: This study aimed to evaluate the "dropout" rates from treatment and associated factors among elderly patients attending a tertiary care psychiatry outpatient facility. Materials and Methods: Data of 1422 patients aged ≥60 years, attending the walk-in clinic were evaluated. Results: Out of 1422 patients, 406 (28.55%) belonged to the "dropout" group. In the "dropout" group, the age of patients was significantly higher than the followed-up group, and a higher proportion of patients were >70 years old...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29710531/the-role-of-bevacizumab-on-tumour-angiogenesis-and-in-the-management-of-gynaecological-cancers-a-review
#7
REVIEW
Dinesh Kumar Chellappan, Kun Hooi Leng, Lee Jia Jia, Nur Amirah Binti Abdul Aziz, Wong Chun Hoong, Yap Cheng Qian, Fam Yi Ling, Gwee Sing Wei, Tiong Ying, Jestin Chellian, Gaurav Gupta, Kamal Dua
OBJECTIVE: The study aims to analyze the effectiveness of bevacizumab in addressing the complications associated with gynecological cancers and evaluates effective treatments for various gynecological cancers. METHODS: The study follows a systematic review approach that has been implemented to analyze the qualitative published data from previous studies. Studies related with the trials of angiogenesis and bevacizumab were selected in the review. RESULTS: In general, the management of gynecological cancers include chemotherapy, surgery and radiation therapy...
April 4, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29703297/march-consultation-2
#8
Harminder Singh Dua
No abstract text is available yet for this article.
March 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29703292/cataract-surgery-with-intraocular-lens-implantation-in-3-brothers-with-megalocornea-long-term-follow-up
#9
Marco Messina, Andrew R Ross, Giulio Pocobelli, Dalia G Said, Harminder S Dua
Cataract surgery in patients with megalocornea is challenging because of the large capsular bag in which a conventional intraocular lens (IOL) does not fit and the atrophic nature of the iris. We report the procedures and outcomes of cataract surgery in 6 eyes of 3 brothers with megalocornea. In 2 eyes, a posterior chamber IOL (PC IOL) was inserted and sutured to the iris with 10-0 nylon sutures. In the other 4 eyes, an iris-clip anterior chamber IOL (AC IOL) was inserted. In all cases, the postoperative corrected distance visual acuity (CDVA) was 6/6...
March 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29698813/neuropathic-keratopathy
#10
REVIEW
Harminder S Dua, Dalia G Said, Elisabeth M Messmer, Maurizio Rolando, Jose M Benitez-Del-Castillo, Parwez N Hossain, Alex J Shortt, Gerd Gerling, Mario Nubile, Francisco C Figueiredo, Saaeha Rauz, Leonardo Mastropasqua, Paolo Rama, Christophe Baudouin
Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to frank epithelial defect with or without stromal ulceration (melting) is associated with reduced or absent corneal sensations. Sensory nerves serve nociceptor and trophic functions, which can be affected independently or simultaneously. Loss of trophic function and consequent epithelial breakdown exposes the stroma making it susceptible to enzymatic degradation. Nerve pathology can range from attrition to aberrant re-generation with corresponding symptoms from anaesthesia to hyperaesthesia/allodynia...
April 23, 2018: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29696964/current-therapies-and-targets-for-type-2-diabetes-mellitus-a-review
#11
Dinesh K Chellapan, Wei Sheng Yap, Nurfatihah A Bt Ahmad Suhaimi, Gaurav Gupta, Kamal Dua
The prevalence of type 2 diabetes mellitus (T2DM) has been increasing at an alarming rate. With an increased understanding of the pathophysiology and pathogenesis of T2DM, various new therapeutic options have been developed to target different key defects in T2DM. Incremental innovations of existing therapies either through unprecedented drug combinations, modified drug molecules, or improved delivery systems are capable to nullify some of the undesirable side effects of traditional therapies as well as to enhance effectiveness...
April 24, 2018: Panminerva Medica
https://www.readbyqxmd.com/read/29685382/managing-older-patients-with-head-and-neck-cancer-the-non-surgical-curative-approach
#12
Muhammad Shahid Iqbal, Divyanshu Dua, Charles Kelly, Paolo Bossi
Managing older patients with head and neck cancers poses a challenge due to the often reduced levels of physiological reserve, the frequent comorbidities and treatment related toxicity. These factors have implications on speech, breathing and swallowing functions. Treatment management plans in these patients may result in de-intensification strategies and as a result of this, use of non-standard treatments is increasing. There have been published reports that indicate the addition of concurrent systemic therapy to radiation in selected older patients is feasible, and produces outcomes comparable with younger patients...
April 20, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29684537/genetic-imaging-study-with-tc-99m-trodat-1-spect-in-adolescents-with-adhd-using-oros-methylphenidate
#13
Aynur Pekcanlar Akay, Gamze Çapa Kaya, Samet Kose, Çiğdem Eresen Yazıcıoğlu, Handan Özek Erkuran, Sevay Alşen Güney, Kaya Oğuz, Duygu Keskin, Burak Baykara, Neslihan İnal Emiroğlu, Mine Şencan Eren, Sefa Kızıldağ, Türkan Ertay, Dua Özsoylu, Süha Miral, Hatice Durak, Ali Saffet Gönül, Luis Augusto Rohde
AIM: To examine theeffects on the brain of 2-month treatment withamethylphenidate extended-release formulation (OROS-MPH) using [Tc-99m ] TRODAT-1SPECT in a sample of treatment-naïve adolescents with Attention Deficit/Hyperactivity Disorder (ADHD). In addition, to assess whether risk alleles (homozygosity for 10-repeat allele at the DAT1 gene were associated with alterations in striatal DAT availability. METHODS: Twenty adolescents with ADHD underwent brain single-photon emission computed tomography (SPECT) scans with [Tc-99m ] TRODAT-1 at baseline and two months after starting OROS-MPH treatment with dosages up to 1 mg/kg/day...
April 20, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29682062/dural-ectasia-and-cauda-equina-syndrome-a-rare-complication-of-long-standing-fusion
#14
Vrushali D Bachhav, Sumeet G Dua, Miral D Jhaveri
The clinicoradiological combination of cauda equina syndrome (CES) and dural ectasia is rare and has been described in a few of patients with ankylosing spondylitis (AS). Simultaneous occurrence of these entities in the absence of AS and in patients with long-standing spinal fusion is extremely rare. We present a case of dural ectasia and CES occurring as a long-term complication of instrumented spinal fusion and discuss the pathogenesis, imaging findings, and management options of this elusive disease process...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29673152/beneficial-effect-of-ocimum-sanctum-linn-against-monocrotaline-induced-pulmonary-hypertension-in-rats
#15
Himanshu Meghwani, Pankaj Prabhakar, Soheb A Mohammed, Pamila Dua, Sandeep Seth, Milind P Hote, Sanjay K Banerjee, Sudheer Arava, Ruma Ray, Subir Kumar Maulik
BACKGROUND: The study was designed to explore any beneficial effect of Ocimum sanctum (Linn) (OS) in experimental pulmonary hypertension (PH) in rats. OS is commonly known as “holy basil” and “Tulsi” and is used in the Indian System of Medicine as antidiabetic, antioxidant, hepatoprotective, adaptogenic, and cardioprotective. METHODS: Monocrotaline (MCT) administration caused development of PH in rats after 28 days and rats were observed for 42 days...
April 17, 2018: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29660388/outcomes-of-gracilis-muscle-flaps-in-the-management-of-groin-complications-after-arterial-bypass-with-prosthetic-graft
#16
Anahita Dua, Vy T Ho, Christina Rao, Sapan S Desai
INTRODUCTION: This study details two-year outcomes of a modified gracilis muscle flap (GMF) technique in providing tissue coverage for groin complications after arterial bypass surgery with synthetic graft. METHODS: All patients who developed groin infections after lower extremity arterial bypass with synthetic graft that underwent a GMF were included from June 2014 to March 2017 from a prospectively collected, purpose-built institutional database. Modifications to the standard technique included identification of the muscle using ultrasound to ensure precise skip incisions, preservation of the segmental blood supply, widening of the tunnel through which the muscle is retroflexed, placement of a wound VAC for healing, and lifelong antibiotics...
April 13, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29644901/eccentric-mature-osseous-cap-a-distinct-imaging-feature-of-sinonasal-osteoblastoma
#17
Sumeet G Dua, Philip H Locker, Isolina R Rossi, Danny Jandali, Paulo Gattuso, Pete S Batra, Bobby A Tajudeen
BACKGROUND: With the exception of osteomas, bone neoplasms that originate in the sinonasal cavity are seldom diagnosed on preoperative imaging due to a lack of characteristic radiographic features. Here we described the unusual occurrence of an osteoblastoma in the paranasal sinuses, and we drew focus to its salient imaging features. A highly unique imaging sign was indicated, and its pathologic basis was explained, with concurrent review of the literature. METHODS: Case series and review of the literature...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29643563/induction-of-anaesthesia-in-cyanotic-heart-diseases-ketomidate-to-the-rescue
#18
Nupur Dua, Anju R Bhalotra
No abstract text is available yet for this article.
March 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29620416/immunological-axis-of-curcumin-loaded-vesicular-drug-delivery-systems
#19
Dinesh K Chellappan, Zhao Yin Ng, Jin-Ying Wong, Alan Hsu, Peter Wark, Nicole Hansbro, Jack Taylor, Jithendra Panneerselvam, Thiagarajan Madheswaran, Gaurav Gupta, Mary Bebawy, Philip M Hansbro, Kamal Dua
Several vesicular systems loaded with curcumin have found their way in the therapeutic applications of several diseases, primarily acting through their immunological pathways. Such systems use particles at a nanoscale range, bringing about their intended use through a range of complex mechanisms. Apart from delivering drug substances into target tissues, these vesicular systems also effectively overcome problems like insolubility and unequal drug distribution. Several mechanisms are explored lately by different workers, and interest over vesicular curcumin has been renewed in the past decade...
April 5, 2018: Future Medicinal Chemistry
https://www.readbyqxmd.com/read/29615397/deep-anterior-lamellar-keratoplasty-dissection-plane-with-viscoelastic-and-air-can-be-different
#20
Andrew R Ross, Dalia G Said, Abdalla El-Amin, Saif Altaan, Javier Cabrerizo, Mario Nubile, Emily Hogan, Leonardo Mastropasqua, Harminder Singh Dua
AIMS: To investigate and define the nature of big bubbles (BB) formed by injection of viscoelastic in deep anterior lamellar keratoplasty. METHODS: Intrastromal injections of 0.1 and 0.3 mL of sodium hyaluronate 1.2% and 0.6% were made into sclera-corneal discs (n = 32) at superficial (anterior-third), midstromal (middle-third) and deep (posterior-third) levels to simulate deep anterior lamellar keratoplasty. Postinjection optical coherence tomograms (OCT) were obtained with the needle in situ...
April 3, 2018: British Journal of Ophthalmology
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