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https://www.readbyqxmd.com/read/28734663/mtdna-sequence-diversity-of-hazara-ethnic-group-from-pakistan
#1
Allah Rakha, Fatima, Min-Sheng Peng, Atif Adan, Rui Bi, Memona Yasmin, Yong-Gang Yao
The present study was undertaken to investigate mitochondrial DNA (mtDNA) control region sequences of Hazaras from Pakistan, so as to generate mtDNA reference database for forensic casework in Pakistan and to analyze phylogenetic relationship of this particular ethnic group with geographically proximal populations. Complete mtDNA control region (nt 16024-576) sequences were generated through Sanger Sequencing for 319 Hazara individuals from Quetta, Baluchistan. The population sample set showed a total of 189 distinct haplotypes, belonging mainly to West Eurasian (51...
July 10, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28734275/low-level-of-autophagy-related-gene-10-atg10-expression-in-the-6-hydroxydopamine-rat-model-of-parkinson-s-disease
#2
Marzieh Shams Nooraei, Ali Noori-Zadeh, Shahram Darabi, Farzad Rajaei, Zohreh Golmohammadi, Hojjat Allah Abbaszadeh
Background: Autophagy is a mechanism disassembling the damaged organelles from the cell. This study attempted to examine the expression of several autophagy-related genes in Parkinson’s disease (PD) rat model. Methods: The male Wistar rats were divided into three groups as control, sham, and lesion. In the latter group, the PD rat model was induced by the injection of 6-hydroxydopamine in the striatum.The behavioral test was conducted one (baseline) and four weeks after the surgery through apomorphine hydrochloride...
July 23, 2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28725507/giant-cell-tumor-of-the-capitate-treated-with-excision-and-midcarpal-fusion
#3
Ayat Allah Oufkir, Cyril Lazerges, Bertrand Coulet, Michel Chammas
Background  Giant cell tumor (GCT) of bone is rare in the carpus, and only 11 cases have been reported in the capitate bone. The problem with this location is the high recurrence rate due to easy extension to the adjacent joint spaces and bones. We describe a case of GCT on the capitate bone and the treatment in comparison with the previously reported cases. Case Description  The case report concerns a 48-year-old woman with a GCT of the capitate diagnosed on curettage. The treatment consisted of large resection with the lunatum and third metacarpal arthrodesis, with a successful union at 2 years follow-up, no recurrence, and an improved function of the wrist...
August 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28717335/evaluation-of-therapeutic-effectiveness-of-prescribed-medications-in-patients-with-type-2-diabetes-mellitus-findings-from-a-tertiary-care-hospital-lahore-pakistan
#4
Bareera Rana, Allah Bukhsh, Tahir Mehmood Khan, Ammar Sarwar, Muhammad Ovais Omer, Shazia Qasim Jamshed
AIM: The present study was aimed to highlight the current prescribing pattern of oral hypoglycemia in type 2 diabetes mellitus and to evaluate the therapeutic effectiveness of these therapeutic categories in achieving target glycemic control. METHODS: This is a prospective, cross-sectional, observational study of 6 months' duration conducted in a tertiary care hospital of Lahore, Pakistan. RESULTS: The current research recruited 145 patients presented in diabetes management center of a tertiary care hospital in Lahore, Pakistan...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28712172/laparoscopic-sleeve-gastrectomy-a-prospective-follow-up-of-30-patients
#5
Asad Ali Toor, Muhammad Waris Farooka, Mahmood Ayyaz, Zeeshan Razzaq, Awais Amjad Malik, Allah Nawaz, Asif Mahmood, Henry Paul Redmond
BACKGROUND: Morbid obesity has become a surgically treatable problem. Laparoscopic sleeve gastrectomy is becoming a popular choice both for surgeons and patients due to effectiveness and low complication rates. METHODS: It was a prospective case series spanning over 6 years. Patient enrolment started from January 2009 and data collection completed in January 2015. Patient with BMI (weight in kilogram/height in meter square) of more than 35 were included in the study...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28706241/abnormal-paraventricular-nucleus-of-hypothalamus-and-growth-retardation-associated-with-loss-of-nuclear-receptor-gene-coup-tfii
#6
Su Feng, Can Xing, Tingyu Shen, Yunbo Qiao, Ran Wang, Jun Chen, Jiaoyang Liao, Zhuo Lu, Xiong Yang, Saber Mohamed Abd-Allah, Jinsong Li, Naihe Jing, Ke Tang
The paraventricular nucleus of hypothalamus plays important roles in the regulation of energy balance and fetal growth. However, the molecular mechanisms underlying its formation and function have not been clearly elucidated. Various mutations in the human COUP-TFII gene, which encodes a nuclear receptor, result in growth retardation, congenital diaphragmatic hernia and congenital heart defects. Here, we show that COUP-TFII gene is expressed in the developing hypothalamus in mouse. The ventral forebrain-specific RXCre/+; COUP-TFII (F/F) mutant mice display growth retardation...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28702453/psychometric-properties-of-the-urdu-version-of-diabetes-knowledge-questionnaire
#7
Allah Bukhsh, Shaun Wen Huey Lee, Priyia Pusparajah, Amer Hayat Khan, Tahir Mehmood Khan
OBJECTIVE: Patient education is a key element in the treatment of diabetes. Assessment of diabetes knowledge is important for optimum treatment. For the assessment of diabetes knowledge, validated tool is essential. None of such validated tool is available in Urdu language. Therefore, the aim of this study was to translate and examine the psychometric properties of the 24-item Urdu version of Diabetes Knowledge Questionnaire (DKQ) among type 2 diabetes patients. METHODS: Standard "forward-backward" process was used to translate DKQ into Urdu language...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28696140/regulatory-roles-of-24-epibrassinolide-in-tolerance-of-acacia-gerrardii-benth-to-salt-stress
#8
Elsayed Fathi Abd Allah, A A Alqarawi, Abeer Hashem, Stephan Wirth, Dilfuza Egamberdieva
This experiment aimed to investigate the role of 24-epibrassinolide (EBL) against NaCl-induced salinity stress in Acacia gerrardii Benth. NaCl (200 mM) imparted deleterious effects on the growth and chlorophyll contents of A. gerrardii, but foliar application of EBL (1.0 mg/l; each plant received 2.5 ml) mitigated the negative effect considerably. NaCl reduced chlorophyll content but this was significantly ameliorated by the application of EBL. EBL reduced significantly NaCl-induced oxidative stress hence protect membranes and also improved the relative water content significantly by 6...
July 11, 2017: Bioengineered
https://www.readbyqxmd.com/read/28691578/a-hybrid-clustering-and-classification-approach-for-predicting-crash-injury-severity-on-rural-roads
#9
Seyed Hessam-Allah Hasheminejad, Mohsen Zahedi, Seyed Mohammad Hossein Hasheminejad
As a threat for transportation system, traffic crashes have a wide range of social consequences for governments. Traffic crashes are increasing in developing countries and Iran as a developing country is not immune from this risk. There are several researches in the literature to predict traffic crash severity based on artificial neural networks (ANNs), support vector machines and decision trees. This paper attempts to investigate the crash injury severity of rural roads by using a hybrid clustering and classification approach to compare the performance of classification algorithms before and after applying the clustering...
July 10, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28669229/cytotoxic-activity-of-alkyl-benzoate-and-fatty-acids-from-the-red-sea-sponge-hyrtios-erectus
#10
Usama W Hawas, Lamia T Abou El-Kassem, Mohamed S Abdelfattah, Mohammed I Y Elmallah, Mennat Allah G Eid, Marwa Monier, M Nithiyanandam
The chemical investigation of the methylene chloride fraction of marine sponge Hyrtios erectus led to the isolation of the known oxysterol (2) along with a new alkyl benzoate compound identified by spectroscopic methods (NMR and MS) as 4'-methylheptyl benzoate (1), whilst the n-butanol fraction afforded the known indole 3-carbaldehyde and β-carboline derivatives. Moreover, the hexane fraction was analysed by GC-MS for their fatty acids (FAs). A total of 17 FAs with chain lengths between 14 and 25 carbons were identified...
July 3, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28655985/circulating-adipokines-in-children-with-nonalcoholic-fatty-liver-disease-possible-noninvasive-diagnostic-markers
#11
Amal Ahmed Mohamed, Said Sabry, Asmaa Mahmoud Abdallah, Naglaa Adly Abd Elazeem, Doaa Refaey, Hebat Allah Fadel Algebaly, Gamal Abo El Fath, Heba Omar
BACKGROUND: The growing obesity pandemic is the leading cause for increasing prevalence of nonalcoholic fatty liver disease (NAFLD) in children. Histopathological evaluation of the liver remains the gold standard for NAFLD diagnosis, but it is an invasive procedure with a low but real risk of morbidity and mortality. The current study evaluated circulating chemerin and adiponectin as possible noninvasive diagnostic markers for NAFLD in obese non-diabetic children. METHODS: A prospective case-control study was conducted, which included 101 obese children with biopsy-proven NAFLD and 57 age- and sex-matched controls...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28652149/effects-of-sucrose-fatty-acid-esters-on-the-stability-and-bonding-performance-of-high-amylose-starch-based-wood-adhesive
#12
Zia-Ud-Din, Hanguo Xiong, Zhenjiong Wang, Peng Fei, Ikram Ullah, Allah Bakhsh Javaid, Yajie Wang, Wensi Jin, Lei Chen
A facile approach was developed to dramatically boost the performance of high amylose starch-based wood adhesive (HASWA) by addition of sucrose fatty acid esters (SEs). The results showed that the addition of 6% (w/w, dry starch basis) SEs significantly improved the bonding strength in both dry and wet states as well as the mobility and storage stability of the adhesive. The formation of amylose-SEs complexes were proved by blue value or differential scanning calorimetry (DSC) analysis. The results also indicated that the incorporation of SEs into the HASWA hindered the aggregation of latex particles and enhanced the thermal stability of starch molecules...
June 23, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28647274/sonic-hedgehog-pathway-suppression-and-reactivation-accelerates-differentiation-of-rat-adipose-derived-mesenchymal-stromal-cells-toward-insulin-producing-cells
#13
Dian Dayer, Mahmoud Hashemi Tabar, Eskandar Moghimipour, Mohammad Reza Tabandeh, Ata A Ghadiri, Elham Allah Bakhshi, Mahmoud Orazizadeh, Mohammad Ali Ghafari
BACKGROUND AIMS: Sonic hedgehog (Shh) is an intercellular signaling molecule that regulates pancreas development in mammals. Manipulation of Shh signaling pathway can be used as reliable approach to improve the generation of functional insulin-producing cells (IPCs) from mesenchymal stromal cells (MSCs). METHODS: In the present study, a novel differentiation protocol was used to produce IPCs from adipose tissue-derived MSCs (ATDMSCs) based on sequential inhibition and reactivation of Shh pathway...
June 21, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28621584/inactivation-of-nondesiccated-and-desiccated-cronobacter-sakazakii-in-reconstituted-infant-formula-by-combination-of-citral-and-mild-heat
#14
Chao Shi, Zhenyu Jia, Yi Sun, Yifei Chen, Du Guo, Zhiyuan Liu, Qiwu Wen, Xiao Guo, Linlin Ma, Baowei Yang, Allah Bux Baloch, Xiaodong Xia
The objective of this study was to evaluate the combined effect of citral plus mild heat on nondesiccated and desiccated Cronobacter sakazakii in reconstituted infant formula. Various concentrations of citral (0, 0.3, 0.6, and 0.9%) combined with various temperatures (25, 45, 50, and 55°C) were applied to nondesiccated and desiccated cocktails of three C. sakazakii strains (approximately 6.0 log CFU mL(-1)) in reconstituted infant formula, and the bacterial populations were assayed periodically. The combined treatments had marked antimicrobial effects on C...
June 16, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28610198/review-of-robber-flies-of-the-genus-i-stichopogon-i-loew-diptera-asilidae-stichopogoninae-from-egypt
#15
Gawhara M M Abu El-Hassan, Haitham B M Badrawy, Sohair M Gad Allah, Ahmed M Soliman, Mohamed S Salama, Salwa K Mohammad
The Egyptian fauna of the asilid genus Stichopogon Loew is revised. Nine species are recognized including two new records, Stichopogon deserti Theodor, 1980 and S. scaliger Loew, 1847. A key to species, lists of material examined and their distribution are included. The occurrence of S. maroccanus in Egypt is discussed and clarified.
March 9, 2017: Zootaxa
https://www.readbyqxmd.com/read/28603137/review-nigella-sativa-prophetic-medicine-a-review
#16
Hira Ijaz, Ume Ruqia Tulain, Junaid Qureshi, Zeeshan Danish, Samina Musayab, Muhammad Furqan Akhtar, Ammara Saleem, Khanzada Khanzada Khan, Muhammad Zaman, Imran Waheed, Imran Khan, Mohamed Abdel-Daim
The present report is a significant effort to explore detail description of N. Sativa, its pharmacognostic characteristics, morphological characteristics, and mechanism of actions, doses and medicinal uses. Nigella sativa (N. Sativa) is greatest form of healing medicine. It is also known as Prophetic Medicine as its use has been mentioned in Prophetic Hadit, as natural remedy for all the diseases except death. It is recommended on daily basis in Tibb-e-Nabwi (Prophetic Medicine). Hazrat Abu Hurairah States ''I have heard from Rasool Allah (PBUH) that there is cure for every disease in black seeds except death and black seeds are shooneeze''...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28603106/hematologic-adverse-effects-and-efficacy-monitoring-in-chronic-hepatitis-c-patients-treated-with-interferon-and-ribavirin-combination-therapy
#17
Ghazala Rafique, Allah Bukhsh, Asif Gul, Sonia Khiljee, Muhammad Ashraf, Muhammad Ovais Omer
180 million people are affected by chronic Hepatitis C Virus infection globally and more than 50 million in South East Asia. Combination of Interferon and Ribavirin is the current anti-HCV therapy in practice and is associated with certain hematologic adverse effects. In this concurrent observational study the incidence rate of major hematologic adverse effects and efficacy outcomes of Interferon and Ribavirin combination therapy was evaluated in 288 chronic hepatitis C patients at Lahore General Hospital. Levels of Hb, TLC, and Platelets counts were monitored for hematologic adverse effects monitoring, whereas, ALT, AST and bilirubin levels were monitored for efficacy...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28599689/aspartic-acid-racemization-with-correlation-to-age-aforensic-perspective
#18
Qudsia Hassan, Allah Rakha, M Zahid Bashir
OBJECTIVE: To estimate age through aspartic acid racemization of human dentin for forensic analysis, and to calculate the margin of error between chronological age and estimated age by racemization method. STUDY DESIGN: Cross-sectional comparative study. PLACE AND DURATION OF STUDY: Dental Outpatients' Department, Ziauddin Hospital, Karachi, from 2011 to 2014. METHODOLOGY: Patients from dental orthodontics department were selected...
May 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28579406/revisiting-the-management-of-recurrent-implantation-failure-through-freeze-all-policy
#19
Yasmin Magdi, Ahmed El-Damen, Ahmed Mohamed Fathi, Ahmed Mostafa Abdelaziz, Mohamed Abd-Elfatah Youssef, Ahmed Abd-Elmaged Abd-Allah, Mona Ahmed Elawady, Mohamed Ahmed Ibrahim, Yehia Edris
OBJECTIVE: To determine whether a freeze-all policy for in vitro human blastocysts improves the ongoing pregnancy rate in patients with recurrent implantation failure (RIF). DESIGN: Prospective cohort study. SETTING: Single private center. PATIENT(S): A total of 171 women with RIF divided into two groups: freeze-all policy group (n = 81) and fresh embryo transfer (ET) group (n = 90). INTERVENTION(S): Freeze-all policy...
July 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28562425/rotational-and-collic-vestibular-evoked-myogenic-potential-testing-in-normal-developing-children-and-children-with-combined-attention-deficit-hyperactivity-disorder
#20
Younes Lotfi, Nima Rezazadeh, Abdollah Moossavi, Hojjat Allah Haghgoo, Reza Rostami, Enayatollah Bakhshi, Faride Badfar, Sedigheh Farokhi Moghadam, Vahid Sadeghi-Firoozabadi, Yousef Khodabandelou
OBJECTIVES: Vestibular dysfunction in childhood can have a major effect on a child's developmental process. Balance function has been reported to be poorer in children with attention deficit and hyperactivity disorder (ADHD) than in their typically developing peers. Due to contradictory available evidence and the paucity of research on vestibular function specifically in children with combined ADHD (cADHD), we designed this aged-matched study to assess vestibular function in children with cADHD...
May 26, 2017: Ear and Hearing
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