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https://www.readbyqxmd.com/read/28444469/modelling-the-unaids-90-90-90-treatment-cascade-for-gay-bisexual-and-other-men-who-have-sex-with-men-in-south-africa-using-the-findings-of-a-data-triangulation-process-to-map-a-way-forward
#1
Andrew Scheibe, Michael Grasso, Henry Fisher Raymond, Albert Manyuchi, Thomas Osmand, Tim Lane, Helen Struthers
A data triangulation exercise was carried out between 2013 and 2015 to assess the HIV epidemic and response among gay, bisexual and other men who have sex with men (GBMSM) in South Africa. We used the findings to assess progress in achieving the UNAIDS 90-90-90 goals for GBMSM in the country. Three scenarios were developed using different GBMSM population factors (2.0, 3.5 and 5.0% of males aged ≥15) to estimate the population size, HIV prevalence of 13.2-49.5%, and 68% of GBMSM knowing their status. Due to data gaps, general population data were used as estimates of GBMSM on antiretroviral therapy (ART) and virologically suppressed (25...
April 25, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28442803/effects-of-fitness-training-on-physical-fitness-parameters-and-quality-of-life-in-human-immunodeficiency-virus-positive-indian-females
#2
Renuka Patil, Apurv Shimpi, Savita Rairikar, Ashok Shyam, Parag Sancheti
PURPOSE: Highly active antiretroviral therapy has significantly extended survival of human immunodeficiency virus (HIV) infected patients. These drugs suppress replication of HIV but at the same time, have many physical and mental side effects which may affect daily activities of the patients. The present study assessed if moderate intensity exercise program helped in enhancing the physical fitness and quality of life (QoL) in HIV positive females which may reduce the comorbidities associated with the disease and medications...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28403830/effectiveness-of-progressive-resistive-exercise-pre-in-the-context-of-hiv-systematic-review-and-meta-analysis-using-the-cochrane-collaboration-protocol
#3
Kelly K O'Brien, Anne-Marie Tynan, Stephanie A Nixon, Richard H Glazier
BACKGROUND: HIV is increasingly considered a chronic illness. More individuals are living longer and aging with the health-related consequences associated with HIV and multi-morbidity. Exercise is a self-management approach that can promote health for people aging with HIV. We examined the safety and effectiveness of progressive resistive exercise (PRE) interventions on immunological, virological, cardiorespiratory, strength, weight, body composition, and psychological outcomes in adults living with HIV...
April 12, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28387447/withdrawn-interventions-for-fatigue-and-weight-loss-in-adults-with-advanced-progressive-illness
#4
REVIEW
Cathy Payne, Philip J Wiffen, Suzanne Martin
BACKGROUND: Fatigue and unintentional weight loss are two of the commonest symptoms experienced by people with advanced progressive illness. Appropriate interventions may bring considerable improvements in function and quality of life to seriously ill people and their families, reducing physical, psychological and spiritual distress. OBJECTIVES: To conduct an overview of the evidence available on the efficacy of interventions used in the management of fatigue and/or unintentional weight loss in adults with advanced progressive illness by reviewing the evidence contained within Cochrane reviews...
April 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28377397/experiences-participating-in-a-community-based-exercise-programme-from-the-perspective-of-people-living-with-hiv-a-qualitative-study
#5
Chantal A Montgomery, Katherine J Henning, Sarah R Kantarzhi, Tamar B Kideckel, Cheryl F M Yang, Kelly K O'Brien
OBJECTIVES: Our aim was to explore the experiences of engaging in a community-based exercise programme (CBEP) from the perspective of people living with HIV (PLWH). DESIGN: We conducted a descriptive qualitative study using semistructured interviews. SETTING: We recruited adults living with HIV who participated in a 16-week CBEP in Toronto, Canada. PARTICIPANTS: 11 participants, the majority men (64%), with a median age of 52 years, and living with a median of 5 concurrent health conditions in addition to HIV participated in the study...
April 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28361500/the-role-of-family-planning-in-achieving-safe-pregnancy-for-serodiscordant-couples-commentary-from-the-united-states-government-s-interagency-task-force-on-family-planning-and-hiv-service-integration
#6
REVIEW
Jennifer Mason, Amy Medley, Sarah Yeiser, Vienna R Nightingale, Nithya Mani, Tabitha Sripipatana, Andrew Abutu, Beverly Johnston, D Heather Watts
INTRODUCTION: People living with HIV (PLHIV) have the right to exercise voluntary choices about their health, including their reproductive health. This commentary discusses the integral role that family planning (FP) plays in helping PLHIV, including those in serodiscordant relationships, achieve conception safely. The United States (US) President's Emergency Plan for AIDS Relief (PEPFAR) is committed to meeting the reproductive health needs of PLHIV by improving their access to voluntary FP counselling and services, including prevention of unintended pregnancy and counselling for safer conception...
March 8, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28359212/a-randomized-clinical-trial-of-adolescents-with-hiv-aids-pediatric-advance-care-planning
#7
Maureen E Lyon, Lawrence J D'Angelo, Ronald H Dallas, Pamela S Hinds, Patricia A Garvie, Megan L Wilkins, Ana Garcia, Linda Briggs, Patricia M Flynn, Sohail R Rana, Yao Iris Cheng, Jichuan Wang
The objective of this study is to determine if pediatric advance care planning (pACP) increases adolescent/family congruence in end-of-life (EOL) treatment preferences longitudinally. Adolescents aged 14-21 years with HIV/AIDS and their families were randomized (N = 105 dyads) to three-60-minute sessions scheduled one week apart: either the pACP intervention (survey administered independently, facilitated conversation with adolescent and family present, completion of legal advance directive document with adolescent and family present) or an active control (developmental history, safety tips, nutrition and exercise education)...
March 30, 2017: AIDS Care
https://www.readbyqxmd.com/read/28353539/coronary-artery-endothelial-dysfunction-is-present-in-hiv-positive-individuals-without-significant-coronary-artery-disease
#8
Micaela Iantorno, Michael Schär, Sahar Soleimanifard, Todd T Brown, Richard Moore, Patricia Barditch-Crovo, Matthias Stuber, Shenghan Lai, Gary Gerstenblith, Robert G Weiss, Allison G Hays
OBJECTIVE: HIV+ individuals experience an increased burden of coronary artery disease (CAD) not adequately accounted for by traditional CAD risk factors. Coronary endothelial function (CEF), a barometer of vascular health, is depressed early in atherosclerosis and predicts future events but has not been studied in HIV+ individuals. We tested whether CEF is impaired in HIV+ subjects without CAD as compared to an HIV- population matched for cardiac risk factors. DESIGN/METHODS: In this observational study, CEF was measured noninvasively by quantifying isometric handgrip exercise (IHE)-induced changes in coronary vasoreactivity with MRI in 18 participants with HIV but no CAD (HIV+CAD-, based on prior imaging), 36 age- and cardiac risk factor-matched healthy participants with neither HIV nor CAD (HIV-CAD-), 41 subjects with no HIV but with known CAD (HIV-CAD+) and 17 subjects with both HIV and CAD (HIV+CAD+)...
March 28, 2017: AIDS
https://www.readbyqxmd.com/read/28327461/muscle-strength-is-impaired-in-men-but-not-in-women-living-with-hiv-taking-antiretroviral-therapy
#9
Vitor Hf Oliveira, Susana L Wiechmann, Argéria Ms Narciso, Allison R Webel, Rafael Deminice
BACKGROUND: There is evidence that HIV Antiretroviral Therapy adverse effects may be sex-dependent, but data examing these sex differences in muscle strength is scarce. Our aim was to compare dynamic and isokinetic parameters of muscle strength between HIV-infected men and women to HIV-uninfected subjects. METHODS: In this cross-sectional study, muscle strength was evaluated in 44 HIV-infected (20 men, 24 women) and 25 age-, race- and body mass index-matched HIV-uninfected subjects (11 men, 14 women)...
March 22, 2017: Antiviral Therapy
https://www.readbyqxmd.com/read/28325087/physical-activity-correlates-in-people-living-with-hiv-aids-a-systematic-review-of-45-studies
#10
Davy Vancampfort, James Mugisha, Justin Richards, Marc De Hert, Michel Probst, Brendon Stubbs
PURPOSE: Understanding barriers and facilitators of physical activity participation in persons living with HIV/AIDS is an essential first step in order to devise effective interventions. The present review provides a systematic quantitative review of the physical activity correlates in people with HIV/AIDS. METHODS: Major electronic databases were searched till August 2016. Keywords included "physical activity" or "exercise" or "sports" and "AIDS" or "HIV". RESULTS: Out of 55 correlates from 45 studies (N = 13,167; mean age range = 30...
March 22, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28296533/polypharmacy-infectious-diseases-sexual-behavior-and-psychophysical-health-among-anabolic-steroid-using-homosexual-and-heterosexual-gym-patrons-in-san-francisco-s-castro-district
#11
Eric J Ip, Michael A Yadao, Bijal M Shah, Shadi Doroudgar, Paul J Perry, Michael J Tenerowicz, Lindsay Newsom, Amber A Mann, Hermine Mkrtchyan, Harrison G Pope
BACKGROUND: Limited studies based in England and Australia reported misuse of anabolic-androgenic steroids (AAS) among homosexual men to enhance body image. Anecdotally, AAS are also being misused by homosexual men in the United States. Since many AAS and certain performance enhancing drugs (PEDs) are administered via injection, this poses a potential vector for the spread of infectious disease in an already at-risk population. OBJECTIVES: This study compared and contrasted homosexual and heterosexual male gym clients regarding use of AAS and PEDs, use of alcohol and illicit drugs, seroprevalence of infectious disease, engagement in risky injection practices and sexual behaviors, and presence of psychiatric conditions...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28276745/predicting-adherence-to-combination-antiretroviral-therapy-for-hiv-in-tanzania-a-test-of-an-extended-theory-of-planned-behaviour-model
#12
Kasia Banas, Ramsey A Lyimo, Harm J Hospers, Andre van der Ven, Marijn de Bruin
OBJECTIVES: Combination antiretroviral therapy (cART) for HIV is widely available in sub-Saharan Africa. Adherence is crucial to successful treatment. This study aimed to apply an extended theory of planned behaviour (TPB) model to predict objectively measured adherence to cART in Tanzania. DESIGN: Prospective observational study (n = 158) where patients completed questionnaires on demographics (Month 0), socio-cognitive variables including intentions (Month 1), and action planning and self-regulatory processes hypothesised to mediate the intention-behaviour relationship (Month 3), to predict adherence (Month 5)...
February 13, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28241882/systematic-review-of-patient-factors-affecting-adipose-stem-cell-viability-and-function-implications-for-regenerative-therapy
#13
REVIEW
Jajini Varghese, Michelle Griffin, Afshin Mosahebi, Peter Butler
BACKGROUND: The applications for fat grafting have increased recently, within both regenerative and reconstructive surgery. Although fat harvesting, processing and injection techniques have been extensively studied and standardised, this has not had a big impact on the variability of outcome following fat grafting. This suggests a possible larger role of patient characteristics on adipocyte and adipose-derived stem cell (ADSC) viability and function. This systematic review aims to collate current evidence on the effect of patient factors on adipocyte and ADSC behaviour...
February 28, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28222175/factors-associated-with-post-diagnosis-pregnancies-in-women-living-with-hiv-in-the-south-of-brazil
#14
Luciana Barcellos Teixeira, Flávia Bulegon Pilecco, Álvaro Vigo, Maria de Lourdes Drachler, José Carlos de Carvalho Leite, Daniela Riva Knauth
OBJECTIVES: To analyze the factors associated with the occurrence of pregnancies after the diagnosis of infection by HIV. METHODS: Cross-sectional study with women of a reproductive age living with HIV/AIDS cared for in the public services of the city of Porto Alegre, in southern Brazil. The data was analyzed from a comparison between two groups: women with and women without pregnancies after the diagnosis of HIV. Poisson regression models were used to estimate the reasons of prevalence (RP)...
2017: PloS One
https://www.readbyqxmd.com/read/28100210/prevalence-of-psychiatric-morbidity-in-a-community-sample-in-western-kenya
#15
Edith Kwobah, Steve Epstein, Ann Mwangi, Debra Litzelman, Lukoye Atwoli
BACKGROUND: About 25% of the worldwide population suffers from mental, neurological and substance use disorders but unfortunately, up to 75% of affected persons do not have access to the treatment they need. Data on the magnitude of the mental health problem in Kenya is scarce. The objectives of this study were to establish the prevalence and the socio-demographic factors associated with mental and substance use disorders in Kosirai division, Nandi County, Western Kenya. METHODS: This was a cross sectional descriptive study in which participants were selected by simple random sampling...
January 18, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28077069/a-pilot-study-of-brisk-walking-in-sedentary-combination-antiretroviral-treatement-cart-treated-patients-benefit-on-soluble-and-cell-inflammatory-markers
#16
Matteo Bonato, Laura Galli, Laura Passeri, Valeria Longo, Gaspare Pavei, Simona Bossolasco, Cecilia Bertocchi, Massimo Cernuschi, Giuseppe Balconi, Giampiero Merati, Adriano Lazzarin, Antonio La Torre, Paola Cinque
BACKGROUND: Chronic HIV infection is associated with low-level inflammation and increased risk of chronic diseases and mortality. The objective was to assess the effects of moderate intensity exercise on metabolic and inflammatory markers in HIV-infected treated persons. METHODS: This was a pilot study enrolling cART-treated, sedentary persons with metabolic complications in a 12-week protocol, consisting of three sessions per week of 60 min brisk walking with (strength-walk group) or without (walk group) 30 min circuit-training...
January 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28074681/community-based-exercise-in-the-context-of-hiv
#17
Anna Li, Taylor McCabe, Erin Silverstein, Stephanie Dragan, Nancy M Salbach, Mehdi Zobeiry, Sarah Beldick, Chris Godi, Kelly K O'Brien
OBJECTIVE: To identify factors to consider for developing and implementing a community-based exercise (CBE) program for people living with HIV (PLWH). METHODS: We conducted a qualitative descriptive study using semi-structured interviews with PLWH, rehabilitation professionals, and recreation providers from Canada and the United Kingdom. We asked participants to describe their experience with exercise, facilitators, and barriers to accessing and participating in exercise, and factors to consider in developing a CBE program for PLWH...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28062389/internet-based-hiv-prevention-with-at-home-sexually-transmitted-infection-testing-for-young-men-having-sex-with-men-study-protocol-of-a-randomized-controlled-trial-of-keep-it-up-2-0
#18
Brian Mustanski, Krystal Madkins, George J Greene, Jeffrey T Parsons, Brent A Johnson, Patrick Sullivan, Michael Bass, Rebekah Abel
BACKGROUND: Human immunodeficiency virus (HIV) infections are increasing among young men who have sex with men (YMSM), yet few HIV prevention programs have studied this population. Keep It Up! (KIU!), an online HIV prevention program tailored to diverse YMSM, was developed to fill this gap. The KIU! 2.0 randomized controlled trial (RCT) was launched to establish intervention efficacy. OBJECTIVE: The objective of the KIU! study is to advance scientific knowledge of technology-based behavioral HIV prevention, as well as improve public health by establishing the efficacy of an innovative electronic health (eHealth) prevention program for ethnically and racially diverse YMSM...
January 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28060042/hiv-infected-children-in-malawi-have-decreased-performance-on-the-6-minute-walk-test-with-preserved-cardiac-mechanics-regardless-of-antiretroviral-treatment-status
#19
Amy Sims Sanyahumbi, Mina Hosseinipour, Danielle Guffey, Irving Hoffman, Peter N Kazembe, Madeline McCrary, Charles G Minard, Charles Van der Horst, Craig A Sable
INTRODUCTION: We aimed to (1) determine if cardiac disease can be detected in HIV-infected children by strain imaging, and (2) to evaluate differences in exercise performance between HIVinfected on and not yet on antiretroviral therapy (ART) and in HIV-uninfected children by 6- minute walk tests (6MWT) METHODS:: This cross-sectional study evaluated cardiac function by echocardiogram and exercise performance by 6MWT in HIV-infected and uninfected children ages 4 to 18 years in Lilongwe, Malawi...
January 3, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28053012/phylogenetic-tools-for-generalized-hiv-1-epidemics-findings-from-the-pangea-hiv-methods-comparison
#20
Oliver Ratmann, Emma B Hodcroft, Michael Pickles, Anne Cori, Matthew Hall, Samantha Lycett, Caroline Colijn, Bethany Dearlove, Xavier Didelot, Simon Frost, A S Md Mukarram Hossain, Jeffrey B Joy, Michelle Kendall, Denise Kühnert, Gabriel E Leventhal, Richard Liang, Giacomo Plazzotta, Art F Y Poon, David A Rasmussen, Tanja Stadler, Erik Volz, Caroline Weis, Andrew J Leigh Brown, Christophe Fraser
Viral phylogenetic methods contribute to understanding how HIV spreads in populations, and thereby help guide the design of prevention interventions. So far, most analyses have been applied to well-sampled concentrated HIV-1 epidemics in wealthy countries. To direct the use of phylogenetic tools to where the impact of HIV-1 is greatest, the Phylogenetics And Networks for Generalized HIV Epidemics in Africa (PANGEA-HIV) consortium generates full-genome viral sequences from across sub-Saharan Africa. Analyzing these data presents new challenges, since epidemics are principally driven by heterosexual transmission and a smaller fraction of cases is sampled...
January 2017: Molecular Biology and Evolution
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