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Patent foramen ovale

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https://www.readbyqxmd.com/read/28777481/a-human-case-of-slc35a3-related-skeletal-dysplasia
#1
Andrew C Edmondson, Emma C Bedoukian, Matthew A Deardorff, Donna M McDonald-McGinn, Xueli Li, Miao He, Elaine H Zackai
Researchers have identified a subset of Holstein having a range of skeletal deformities, including vertebral anomalies, referred to as complex vertebral malformation due to mutations in the SLC35A3 gene. Here, we report the first case in humans of SLC35A3-related vertebral anomalies. Our patient had prenatally diagnosed anomalous vertebrae, including butterfly, and hemivertebrae throughout the spine, as well as cleft palate, micrognathia, patent foramen ovale, patent ductus arteriosus, posterior embryotoxon, short limbs, camptodactyly, talipes valgus, rocker bottom feet, and facial dysmorphism including proptosis, nevus flammeus, and a cupped left ear...
August 4, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28761399/potential-role-of-patent-foramen-ovale-in-exacerbating-hypoxemia-in-chronic-pulmonary-disease
#2
REVIEW
Michael E Layoun, Jamil A Aboulhosn, Jonathan M Tobis
Patent foramen ovale has been associated with multiple pulmonary diseases, such as pulmonary hypertension, platypnea-orthodeoxia syndrome, and chronic obstructive pulmonary disease. A connection between patent foramen ovale and chronic pulmonary disease was first described more than 2 decades ago in case reports associating patent foramen ovale with more severe hypoxemia than that expected based on the severity of the primary pulmonary disease. It has been suggested that patients with both chronic pulmonary disease and patent foramen ovale are subject to severe hypoxemia because of the right-to-left shunt...
June 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28756426/handle-with-care-a-ductus-arteriosus-aneurysm-in-an-elderly-patient
#3
Sebastiano Gili, Fulvio Orzan, Fabrizio D'Ascenzo, Antonio Montefusco, Pierluigi Omedé
A ductus arteriosus aneurysm (DAA) was corrected with an 18 mm Amplatzer patent foramen ovale occluder. DAA is a rare finding, with sporadic cases reported (the vast majority in children and infants). In the elderly, it poses serious therapeutic challenges, as the risk of rupture is counterbalanced by the high risk of its correction, which requires surgery or placement of an endovascular prosthesis in a critical region such as the aortic arch.
August 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28751787/successful-percutaneous-transcatheter-patent-foramen-ovale-closure-through-the-right-internal-jugular-vein-using-stiff-amplatzer-catheter-with-a-reshaped-tip
#4
Zaher Fanari, Sumaya Hammami, James T Hopkins
Percutaneous transcatheter closure of a patent foramen ovale (PFO) remains challenging when femoral venous approach is not available. We describe the successful closure of a PFO using the right internal jugular venous approach and a catheter delivery system with a reshaped tip in a patient with a PFO, recurrent stroke, recurrent gastrointestinal bleeding, bilateral deep venous thrombosis and thrombosed bilateral inferior vena cava filter.
August 2016: Delaware Medical Journal
https://www.readbyqxmd.com/read/28747203/migraine-and-percutaneous-patent-foramen-ovale-closure-a-systematic-review-and-meta-analysis
#5
Yu-Jie Shi, Jun Lv, Xing-Ting Han, Guo-Gang Luo
BACKGROUND: The association between patent foramen ovale (PFO) and migraine with aura (MA) is well established. However, the benefits of PFO closure are less certain in patients with migraine without aura (MwoA). METHODS: We systematically searched Pubmed for pertinent clinical studies published from January 2000 to July 2015. The primary end-point was the elimination or significant improvement of migraine symptoms after PFO closure. RESULTS: Upon screening an initial list of 315 publications, we identified eight studies that included 546 patients...
July 26, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28734594/editorial-commentary-closure-of-the-patent-foramen-ovale-viewed-from-a-different-angle
#6
EDITORIAL
Bernhard Meier, Fabian Nietlispach
No abstract text is available yet for this article.
July 11, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28734447/plication-of-the-diaphragm-in-postpneumectomy-right-to-left-shunting
#7
Joyce-Manyi Bakia, Jeroen M A M Retera, Roland P van Ieperen, Robbert J de Winter, Joël van der Niet
A rare adverse event of a right-sided pneumectomy with an elevated hemidiaphragm is right-to-left shunting through a patent foramen ovale. In this case report we describe our experience with plication of the right hemidiaphragm with instantaneous hemodynamic results and pain relief, followed by secondary closure of the foramen ovale.
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28733124/left-upper-lung-lobectomy-is-an-embolic-risk-factor-for-cerebral-infarction
#8
Yuya Kobayashi, Hiroyuki Yahikozawa, Ryota Takamatsu, Rie Watanabe, Kenichi Hoshi, Wataru Ishii, Shunichi Sato
Cerebral embolism is typically caused by a cardiogenic thrombus. The patent foramen ovale is a well-known cause of paradoxical embolism. However, some idiopathic cases of stroke have been reported. Such strokes are designated as embolic stroke of undetermined sources. Among them, lung lobectomy may be a new embolic risk factor for cerebral embolism. The risk of thrombus formation is high at the pulmonary vein stump after lung lobectomy, especially in the left upper lobe. Interestingly, the risk remains several years after surgery...
September 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28732833/the-multiple-dimensions-of-platypnea-orthodeoxia-syndrome-a-review
#9
REVIEW
Abhinav Agrawal, Atul Palkar, Arunabh Talwar
Platypnea-Orthodeoxia syndrome (POS) is a rare clinical entity characterized by dyspnea and arterial desaturation while in the upright position. The various pathophysiologic mechanisms leading to POS has puzzled clinicians for years. The hypoxia in POS has been attributed to the mixing of the deoxygenated venous blood with the oxygenated arterial blood via a shunt. The primary mechanisms of POS in these patients can be broadly classified based on intracardiac abnormalities, extracardiac abnormalities and miscellaneous etiologies...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28721223/atrial-fibrillation-in-a-preterm-newborn-with-structurally-normal-heart
#10
Pier Paolo Bassareo, Andrea Raffaele Marras, Mariangela Marras, Silvia Marras, Giuseppe Mercuro
Atrial fibrillation (AF) is a really uncommon arrhythmia in newborns. Here, we report the case of a 1-day-old infant who was recovered in Neonatal Intensive Care Unit for a twin-to-twin transfusion. The appearance of an unexpected AF was registered at his continuous electrocardiographic monitoring. Both chest X-ray and echocardiographic examination revealed the anomalous insertion of the tip of a central venous catheter (CVC) into the heart ('umbilical artery → inferior vena cava → right atrium → patent foramen ovale → left atrium')...
March 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28721209/recent-advances-in-preventing-stroke-recurrence
#11
REVIEW
J David Spence
Recent advances in secondary stroke prevention include new evidence in hypertension, nutrition, anticoagulation, antiplatelet therapy, intracranial stenosis, percutaneous closure of patent foramen ovale, and lipid-lowering therapy. Individualized therapy for hypertension based on phenotyping with plasma renin and aldosterone markedly improves blood pressure control in patients with resistant hypertension. A Mediterranean diet can reduce the risk of stroke by nearly half. The diagnosis and treatment of metabolic vitamin B12 deficiency, and B vitamins to lower homocysteine, can reduce the risk of stroke by approximately 30%...
2017: F1000Research
https://www.readbyqxmd.com/read/28709812/patent-foramen-ovale-and-cryptogenic-stroke
#12
REVIEW
Koki Nakanishi, Minoru Yoshiyama, Shunichi Homma
The presence of a patent foramen ovale (PFO) has been found to be associated with an increased risk of cryptogenic stroke in many case-control studies. This paper reviews the current understanding of the pathophysiology and diagnosis of PFO, and therapeutic options of patients with PFO and cryptogenic stroke.
July 4, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28705105/clinical-outcomes-of-secondary-prevention-strategies-for-young-patients-with-cryptogenic-stroke-and-patent-foramen-ovale
#13
Alessandra Danese, Chiara Stegagno, Giampaolo Tomelleri, Anna Piccoli, Giulia Turri, Monica Carletti, Andrea Variola, Maurizio Anselmi, Sara Mazzucco, Angela Ferrara, Paolo Bovi, Nicola Micheletti, Manuel Cappellari, Salvatore Monaco, Corrado Vassanelli, Flavio Ribichini
Background The aim of this study was to compare the immediate and long-term clinical outcomes of medical therapy and percutaneous patent foramen ovale (PFO) closure as secondary prevention strategies in patients younger than 55 years of age presenting with cryptogenic stroke and PFO. Methods Between January 2006 and April 2015, all patients with the diagnosis of cryptogenic stroke and PFO were analysed and prospectively followed. Stroke was confirmed in 159 out of 309 patients (51%). In the remaining cases, other neurological conditions were found and therefore excluded from further analysis...
August 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28698422/-atrial-septal-hematoma-after-repair-of-ventricular-septal-defect-report-of-a-case
#14
Akihisa Furuta, Takahiko Sakamoto, Mitsugi Nagashima, Goki Matsumura, Toshihide Nishimori, Jin Ikarashi, Yuuichi Matsuzaki, Syou Akiyama, Kenji Yamazaki
A 3-month-old female with ventricular septal defect underwent definitive repair. In the operation, a venting tube was inserted through the incised patent foramen ovale. The ventricular septal defect was closed using a patch and the incised patent foramen ovale was directly closed. A transesophageal echography showed no abnormal findings in the operating room. On 1st postoperative day, the patient's heart rate and pressure of the superior vena cava increased while blood pressure decreased. A transthoracic echocardiography revealed an atrial septal hematoma...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28696881/persistent-left-superior-vena-cava-incidence-and-management-in-patients-undergoing-repair-of-partial-anomalous-pulmonary-venous-connection
#15
Nicholas S Clarke, Raghav A Murthy, Kristine J Guleserian
INTRODUCTION: A association between partial anomalous pulmonary venous connection (PAPVC) and systemic venous anomalies has been described in the literature, but the true incidence is yet to be elucidated. At our institution, we sought to find the incidence of a persistent left superior vena cava (PLSVC) in patients undergoing an operation for PAPVC. METHODS: A retrospective review of all pediatric and adult patients with PAPVC who underwent surgical repair from February 2006 to February 2016...
July 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28694247/a-case-of-unprovoked-precarious-patent-foramen-ovale-protuberance
#16
H Z R McConkey, M Ghosh-Dastidar, S R Redwood, V Bapat
This is a case of a precarious thrombotic mass straddling a patent foramen ovale which had already embolised to the pulmonary circulation. The diagnosis was initially deceptive and management challenging. LEARNING POINTS: Echocardiography is mandated and can change management in haemodynamically unstable patients with pulmonary emboli.Pulmonary embolism can be life-threatening.The authors propose that urgent cardiac surgery is the safest treatment in the setting of highly mobile, large volume, intra-cardiac thrombus...
September 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/28684051/patent-foramen-ovale-closure-to-prevent-secondary-neurologic-events
#17
REVIEW
Rosie Jasper, James C Blankenship
In October of 2016 the United States Food and Drug Administration approved the Amplatzer Patent Foramen Ovale (PFO) occluder device for use in patients with cryptogenic stroke, to reduce the risk of recurrent stroke. This event followed 15years of off-label use of atrial septal occluder devices, 3 randomized trials, and enormous controversy over the efficacy of this procedure. While none of the trials reached the primary endpoint needed to prove the efficacy of PFO closure in preventing recurrent stroke, meta-analyses and 5-year follow-up of 1 trial suggest that PFO closure decreases the risk of recurrent stroke, especially in sub-groups with large shunts and atrial septal aneurysms, and especially when the Amplatzer device (rather than other devices) is used...
July 3, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28677480/preoperative-venovenous-ecmo-in-an-infant-with-late-diagnosis-of-hypoplastic-left-heart-syndrome
#18
Lena K Eschenbach, Jelena Kasnar-Samprec, Kilian Ackermann, Christian Schreiber, Rudiger Lange, Julie Cleuziou
Late diagnosis and late referral for the Norwood stage 1 procedure in patients with hypoplastic left heart syndrome is rare and associated with a higher mortality. We present a case of a cyanotic almost five-week-old infant with hypoplastic left heart syndrome, highly restrictive foramen ovale, and patent ductus arteriosus, who was bridged with venovenous extracorporeal membrane oxygenation to the Norwood stage 1 procedure.
January 1, 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28673417/neurologic-injuries-in-noncontact-sports
#19
REVIEW
Robert J Marquardt, Andrew Blake Buletko, Andrew Neil Russman
Noncontact sports are associated with a variety of neurologic injuries. Concussion, vascular injury (arterial dissection), and spinal cord trauma may be less common in noncontact sports, but require special attention from the sports neurologist. Complex regional pain disorders, muscle injury from repetitive use, dystonia, heat exposure, and vascular disorders (patent foramen ovale), occur with similar frequency in noncontact and contact sports. Management of athletes with these conditions requires an understanding of the neurologic consequences of these disorders, the risk of injury with return to play, and consideration for the benefits of exercise in health restoration and disease prevention...
August 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28671864/a-case-report-on-pulmonary-arteriovenous-fistula-with-recurrent-cerebral-infarction
#20
Lu He, Ge-Sheng Cheng, Ya-Juan Du, Yu-Shun Zhang
Patent foramen ovale (PFO) and pulmonary arteriovenous fistula (PAVF) have been both proposed as a mechanism for cerebral infarction. However, there are only a few reports on how to distinguish the role of the two factors in cerebral infarction.
June 20, 2017: Heart Surgery Forum
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