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Renata C Portela, Nikoly T Fares, Lilian F Machado, Amanda F São Leão, Denise de Freitas, Augusto Paranhos, Tiago S Prata, Carolina P B Gracitelli
PURPOSE: To assess ocular surface disease (OSD) in glaucoma using clinical parameters, self-report assessment and keratograph analysis. METHODS: A total of 30 glaucoma patients and 27 subjects with cataracts (control group) were enrolled in the study. Only glaucoma patients who were using at least 1 topical intraocular pressure (IOP)-lowering medication were included. An ophthalmological examination was performed, including tear break-up time, assessment of conjunctival hyperemia and keratitis, and completion of the Ocular Surface Disease Index (OSDI) questionnaire...
June 18, 2018: Journal of Glaucoma
Elizabeth C Fung, Mariana G R Santos, Zila M Sanchez, Pamela J Surkan
Violence among young adults is an increasing public health concern, especially in the context of nightlife, such as around nightclubs and bars. Nightlife is associated with alcohol, drugs, and increased violence, but little is known about personal and environmental factors related to physical aggression and sexual violence in nightclubs. This study aimed to determine personal and environmental risk factors for physical and sexual aggression in nightclubs in São Paulo, Brazil. Data were collected among nightclub patrons through use of a portal survey at the entrances and exits of 31 nightclubs...
June 1, 2018: Journal of Interpersonal Violence
Danilo Garcia Sanchez, Fernanda Maciel de Melo, Eduardo Angelino Savazzi, Eliana Guedes Stehling
Bacterial resistance occurs by spontaneous mutations or horizontal gene transfer mediated by mobile genetic elements, which represents a great concern. Resistance to β-lactam antibiotics is mainly due to the production of β-lactamases, and an important mechanism of fluoroquinolone resistance is the acquisition plasmid determinants. The aim of this study was to verify the presence of β-lactamase-encoding genes and plasmid-mediated quinolone resistance genes in different water samples obtained from São Paulo state, Brazil...
June 16, 2018: Environmental Monitoring and Assessment
Fernanda Maria Silveira Souto, Bárbara Vilela Giampietro, Julia Thiemi Takiuti, Lucia Maria Arruda Campos, Carlos Eduardo Hirata, Joyce Hisae Yamamoto
AIMS: To analyse the clinical features, systemic associations, treatment and visual outcomes of uveitis in children from a referral centre in São Paulo, Brazil. METHODS: Clinical records of patients under 16 years old who attended the Uveitis Service, Hospital das Clinicas, Faculdadede Medicina, Universidade de São PauloFMUSP, between April and September 2017, were reviewed retrospectively. Patients with incomplete medical records, previous ocular trauma, or less than six6 months of follow-up were excluded...
June 15, 2018: British Journal of Ophthalmology
Alvaro J Leite, Ana I Gonçalves, Marcia T Rodrigues, Manuela E Gomes, João F Mano
The present work explores bioactive glass nanoparticles (BGNPs) and developed strontium-doped nanoparticles (BGNPsSr), envisioning orthopedic strategies compatible with vascularization. The nanoparticles were synthesized by sol-gel, achieving a diameter of 55 nm for BGNPs and of 75 nm for BGNPsSr, and the inclusion of strontium caused none structural alteration. The nanoparticles exhibited high cytocompatibility for HUVECs and SaOS-2. Additionally, the incorporation of strontium emphasized the tubule networking behavior of HUVECs...
June 15, 2018: ACS Applied Materials & Interfaces
Gang Liu, Dongtang Yuan, Peng Sun, Weidong Liu, Peng-Fei Wu, Huan Liu, Guang-Yang Yu
Osteosarcoma is recognized as a malignant tumor in the skeletal system. Long non-coding RNAs (lncRNAs) have been exhibited to play crucial roles in osteosarcoma development. Our current study focused on the biological effects and mechanism of LINC00968 in osteosarcoma pathogenesis. We observed that LINC00968 was dramatically elevated in osteosarcoma cells including U2OS, MG63, Saos-2, SW1353, and 143-B cells compared to human osteoblast cell line hFOB. Silence of LINC00968 inhibited osteosarcoma cell growth and proliferation in vitro...
June 15, 2018: Journal of Cellular Physiology
Ednilse Leme, Ericka P Silva, Paula S Rodrigues, Igor R Silva, Maria F M Martins, Eduardo F Bondan, Maria M Bernardi, Thiago B Kirsten
The Billings reservoir is the largest water-storage facility in the São Paulo Metropolitan Region, with only a small part of the reservoir used for water supply. Recently, the São Paulo Metropolitan Region has experienced the greatest water collapse ever recorded. Thus, the intensification of use of the Billings reservoir should be considered. The objective of this study was to evaluate the quality of the water from different areas of the Billings reservoir related to human consumption (water supply and fishing): Rio Pequeno, Rio Grande, and Bororé rivers...
June 11, 2018: Ecotoxicology and Environmental Safety
Fei-Fei Li, Bo Zhang, Ji-Hong Cui, Fu-Lin Chen, Yin Ding, Xue Feng
Mechanical load application promotes bone formation, while reduced load leads to bone loss. However, the underlying mechanisms that regulate new bone formation are not fully understood. Wnt/β‑catenin signaling has an important role in bone formation, bone growth and remodeling. The aim of the present study was to investigate whether mechanical stimuli regulated bone formation through the Wnt/β‑catenin signaling pathway. Saos‑2 osteoblastic cells were subjected to mechanical strain using a Flexcell strain loading system...
June 7, 2018: Molecular Medicine Reports
Silverio Catureba da Silva Filho, Amanda Carvalho Miranda, Thadeu Alfredo Farias Silva, Felipe Araújo Calarge, Roberto Rodrigo de Souza, José Carlos Curvelo Santana, Elias Basile Tambourgi
The data presented in this article are related to the research article "Environmental and techno-economic considerations on biodiesel production from waste frying oil in São Paulo city" (Silva Filho et al., 2018) [1]. This article presents the variation of the concentration of waste frying oil (WFO) with the reaction time and temperature during the transesterification of WTOs collected in the residences and restaurants of the city of São Paulo. Then, the biodiesel samples were mixed with the S-10 diesel oil in order to obtain the B10, B20, B30, B40, B50, B75 and B100 blends, which were tested in a diesel engine and their power, fuel consumption and gas emissions (CO, CO2 and SO2 ) have been measured to verify their greenhouse effect and energy efficiency...
June 2018: Data in Brief
Marco D T Scanavino, Ana Ventuneac, Carmita H N Abdo, Hermano Tavares, Maria L S Amaral, Bruna Messina, Sirlene C Reis, João P L B Martins, Jeffrey T Parsons
OBJECTIVE: There is a lack of studies on negative mood states and sexual risk behavior in men of all sexual orientations who seek treatment for excessive sexual behavior (ESB). We aim to examine sexual compulsivity (SC), anxiety, depression, and sexual risk behavior in a treatment-seeking sample of men and controls. METHODS: We enrolled 88 (37 [42%] gay or bisexual and 51 [58%] heterosexual) ESB outpatients and 64 controls. Assessments included the Sexual Compulsivity Scale (SCS), the Beck Anxiety Inventory (BAI), the Beck Depression Inventory (BDI), and sexual risk behaviors...
June 11, 2018: Revista Brasileira de Psiquiatria
Juliana Miyuki do Prado, Leonice Fumiko Sato Kurebayashi, Maria Julia Paes da Silva
OBJECTIVE: To compare the efficacy of experimental auriculotherapy and placebo auriculotherapy with sham points for the treatment of stress in nurses of a charity hospital in São Paulo. METHOD: Randomized, single-blind, controlled trial. The sample consisted of 168 nurses with medium and high stress levels according to the List of Stress Symptoms (LSS). The participants were randomized to three groups: Auriculotherapy (G1), Placebo (G2) and Control (G3). Groups 1 and 2 received 12 sessions, twice a week...
June 11, 2018: Revista da Escola de Enfermagem da U S P
Christiane Santiago Maia, Daniel Roberto Coradi de Freitas, Luciana Guerra Gallo, Wildo Navegantes de Araújo
OBJECTIVE: to describe the adverse events related to health care resulting in death. METHODS: a descriptive study of reports recorded in the Brazilian Health Surveillance Notification System (Notivisa) in Brazil from Jun 2014 to Jun 2016; notifications recorded as 'other' in the 'incident type' were recoded. RESULTS: 417 cases were recorded, mostly in adults and the elderly (85%), with no sex differences; the states of São Paulo (N=92), Paraná (N=75) and Minas Gerais (N=66) were the main reporter; hospitals contributed to 97% of the records, principally in the intensive care and hospitalization sectors; the investigation by the notifying unit occurred in 5% of cases; in the recode of the type of incident, 52 records were recovered; the most common type of incident was 'failures during health care' (50%)...
June 11, 2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
Isabel Marília Peres, Sérgio Paulo Jorge Rodrigues
Jane Marcet's Conversations on chemistry was adapted and published in Portuguese by António Teixeira Girão in 1834, based on a translation of Anselme Payen's adaptation, released in 1825. Girão added many notes and a new chapter to his version. The article analyzes the scientific content and circumstances surrounding publication of Girão's book within the context of the diverse approaches used in adapting Conversations at different moments in time and in different countries. The analysis draws from our compilation of editions accessible online at public libraries around the world...
April 2018: História, Ciências, Saúde—Manguinhos
Marcelo A A Pinheiro, Marcelo R Souza, Luciana C M Santos, Roberto F C Fontes
Ucides cordatus is a relevant fishery resource of Brazilian mangroves and requires legal normative to sustainable use based on stock assessment and management. This study evaluated some population parameters (structure, density, abundance, fishery potential and stock) of this crab species in Brazil Southeast (São Paulo, State), discussing the use of the results to delineate fishery management strategies. Density was monthly evaluated (September 1998 to August 1999), using five sample quadrats of 2x2 m. Density (ind...
April 2018: Anais da Academia Brasileira de Ciências
Luiz Gonzaga Coelho, Carlos Roberto Sant'Ana, Ricardo Brandt de Oliveira, Raíra César E Cezar, Aline Cordeiro Campos de Araujo, Raisa Cristina Teodoro da Silva, Osmar Reni Trindade, Maria Clara Coelho, Eduardo Ferrioli, José Albertino Bendassolli
OBJECTIVE: The 13C-urea breath test is the main non-invasive test for the diagnosis of Helicobacter pylori infection. The availability of this test throughout the country is limited, mainly due to the difficulty in obtaining the labeled isotope from abroad. Recently, researchers from the Nuclear Energy Center in Agriculture at the University of São Paulo (CENA/USP) succeeded in synthesizing 13C-enriched urea for Helicobacter pylori diagnosis. The aim of the study was to compare the performance of the 13C-urea breath test using 13C-urea acquired abroad with that of a test using 13C-urea synthesized in Brazil...
June 7, 2018: Clinics
Alberto Anastacio Amarilla, Marcilio Jorge Fumagalli, Mario Luis Figueiredo, Djalma S Lima-Junior, Nilton Nascimento Santos-Junior, Helda Liz Alfonso, Veronica Lippi, Amanda Cristina Trabuco, Flavio Lauretti, Vanessa Danielle Muller, David F Colón, João P M Luiz, Andreas Suhrbier, Yin Xiang Setoh, Alexander A Khromykh, Luiz Tadeu Moraes Figueiredo, Victor Hugo Aquino
Rocio virus (ROCV) was the causative agent of an unprecedented outbreak of encephalitis during the 1970s in the Vale do Ribeira, Sao Paulo State, in the Southeast region of Brazil. Surprisingly, no further cases of ROCV infection were identified after this outbreak; however, serological surveys have suggested the circulation of ROCV among humans and animals in different regions of Brazil. Cross-protective immunity among flaviviruses is well documented; consequently, immunity induced by infections with other flaviviruses endemic to Brazil could potentially be responsible for the lack of ROCV infections...
2018: PloS One
Caroline Roveri Marin, Renata Cristina Gasparino, Ana Claudia Puggina
OBJECTIVES: 1) To identify the patient's perception of invasion of territorial and personal space and 2) to evaluate whether personal characteristics, housing conditions and characteristics of the hospital unit affect this perception. METHODS: Analytical, cross-sectional and quantitative study. An adapted version of the "Anxiety Due to Territory and Space Intrusion Questionnaire" was applied with patients hospitalized in the internal medicine and maternity wards and in the ward for patients with private health insurance of a university hospital in the state of São Paulo...
2018: PloS One
B A Santos, K R Reinhold-Castro, E C Cristóvão, T G V Silveira, U Teodoro
Leishmaniasis is a vector-borne disease caused by the protozoan Leishmania and it is one of the six most important infectious diseases in the world. The aim of this study was to conduct a research on the fauna and most frequented ecotopes by sandflies on islands of the Paraná River. The sandflies were collected with Falcão light traps in 10 islands in the municipalities of São Pedro do Paraná, Porto Rico, and Querência do Norte, in Paraná State, Brazil, from November 2012 to November 2014. In total, 76,145 specimens of Nyssomyia neivai, the only species found, were collected, of which 63,015 were female and 13,130, male...
June 12, 2018: Journal of Medical Entomology
Li Zhuang, Jinlian Ma, Zhen Yu, Yueqiang Wang, Jia Tang
Ammonia accumulation is a major inhibitory substance causing anaerobic digestion upset and failure in CH4 production. At high ammonia levels, CH4 production through syntrophic acetate oxidization (SAO) pathways is more tolerant to ammonia toxicity than the acetoclastic methanogenesis pathway, but the low CH4 production rate through SAO constitutes the main reason for the low efficiency of energy recovery in anaerobic digesters treating ammonia-rich substrates. In this study, we showed that acetate fermentation to CH4 and CO2 occurred through SAO pathway in the anaerobic reactors containing a high ammonia concentration (5...
June 12, 2018: Microbial Biotechnology
Seyedali Seyedmajidi, Maryam Seyedmajidi, Ebrahim Zabihi, Karimollah Hajian-Tilaki
Considering to the possibility of cellular and genetic damage by the implant materials in the patient and the clinician, the safety of the biomaterials should be evaluated. The purpose of this study was to compare the cytotoxicity and genotoxicity induced by two nanocomposites, hydroxyapatite/bioactive glass (HA/BG) and fluorapatite/bioactive glass (FA/BG) in vitro. Biomaterial extracts (BMEX, 100%) were prepared by incubating 100 mg/mL of each biomaterial powder in complete culture medium (RPMI1640 + 10% FBS) for 72 hours...
June 12, 2018: Journal of Biomedical Materials Research. Part A
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