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https://www.readbyqxmd.com/read/28528521/myeloid-populations-in-systemic-autoimmune-diseases
#1
REVIEW
María Morell, Nieves Varela, Concepción Marañón
Systemic autoimmune diseases (SADs) encompass a wide spectrum of clinical signs as a reflection of their complex physiopathology. A variety of mechanisms related with the innate immune system are in the origin of the loss of self-tolerance in these diseases, and for most of them, the myeloid leukocytes are key actors. Monocytes, macrophages, dendritic cells, and neutrophils are first-line immune effectors located in the interface between innate and adaptive immunity. They are crucial in the organization of the local and systemic responses to damage-associated molecular patterns (DAMPs) and determine the intensity, orientation, and duration of the local immune response through the expression of chemokines, costimulatory or protolerogenic factors...
May 20, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28527134/comparison-of-nurses-and-general-caregivers-knowledge-attitude-and-practice-on-medication-administration-process-and-their-distress-level-in-long-term-care-facilities-across-penang-kuala-lumpur-and-selangor-of-malaysia
#2
Balamurugan Tangiisuran, Sok Cin Tye, May Yen Leow, Rahmat Awang
AIM: Comparing nurses and general caregivers' knowledge, attitude, and practices (KAP) on medication administration process in long-term care (LTC) setting and an assessment of their stress, anxiety, and depression (SAD) level. METHODS: A cross-sectional survey was conducted among nurses and general caregivers working in LTC using a validated questionnaire. Consisting of demographic characteristics (Section 1); 40 questions on KAP (Section 2); and assessment of Depression, Anxiety, and Stress Scale (DASS-21) (Section 3)...
May 19, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28526480/human-seasonal-and-circadian-studies-in-antarctica-halley-75-0-s
#3
Josephine Arendt, Benita Middleton
Living for extended periods in Antarctica exposes base personnel to extremes of daylength (photoperiod) and temperature. At the British Antarctic Survey base of Halley, 75(0)S, the sun does not rise for 110 d in the winter and does not set for 100 d in summer. Photoperiod is the major time cue governing the timing of seasonal events such as reproduction in many species. The neuroendocrine signal providing photoperiodic information to body physiology is the duration of melatonin secretion which reflects the length of the night: longer in the short days of winter and shorter in summer...
May 16, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28526260/relationships-between-school-start-time-sleep-duration-and-adolescent-behaviors
#4
Kyla L Wahlstrom, Aaron T Berger, Rachel Widome
OBJECTIVES: The objectives were 2-fold: (1) to examine how high school start times relate to adolescent sleep duration, and (2) to test associations between sleep duration and mental health- and substance use-related issues and behaviors in teens. DESIGN: This study examines selected questions from survey data collected between 2010 and 2013 high school students. SETTING: Respondents included more than 9000 students in grades 9 to 12 in 8 high schools in 5 school districts across the United States...
June 2017: Sleep Health
https://www.readbyqxmd.com/read/28523366/the-effect-of-cigarette-price-increases-on-cigarette-consumption-tax-revenue-and-smoking-related-death-in-africa-from-1999-to-2013
#5
Li-Ming Ho, Christian Schafferer, Jie-Min Lee, Chun-Yuan Yeh, Chi-Jung Hsieh
OBJECTIVES: This study investigates the effects of price hikes on cigarette consumption, tobacco tax revenues, and reduction in smoking-caused mortality in 36 African countries. METHODS: Using panel data from the 1999-2013 Euromonitor International, the World Bank and the World Health Organization, we applied fixed-effects and random-effects regression models of panel data to estimate the elasticity of cigarette prices and simulate the effect of price fluctuations...
May 18, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28522979/spontaneous-facial-actions-map-onto-emotional-experiences-in-a-non-social-context-toward-a-component-based-approach
#6
Shushi Namba, Russell S Kabir, Makoto Miyatani, Takashi Nakao
While numerous studies have examined the relationships between facial actions and emotions, they have yet to account for the ways that specific spontaneous facial expressions map onto emotional experiences induced without expressive intent. Moreover, previous studies emphasized that a fine-grained investigation of facial components could establish the coherence of facial actions with actual internal states. Therefore, this study aimed to accumulate evidence for the correspondence between spontaneous facial components and emotional experiences...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28516959/adaptive-psychological-structure-in-childhood-hearing-impairment-audiological-correlations
#7
A Serra, G Spinato, S Cocuzza, L Licciardello, P Pavone, L Maiolino
The present research deals with the clinical and social problems present during linguistic and cognitive development of deaf children. Currently, the development of Theory of Mind represents an important research field in deafness studies. These international studies highlighted a significant alteration in the development of Theory of Mind in deaf children compared to normal hearing children, especially in cases of congenital or preverbal hearing loss. In particular, the research focuses on the skills of deaf children in recognising emotions and desires, through both perceptive and cognitive methods, by evaluation of psycho-cognitive skills of children with severe hearing loss using a set of questions to be administered to hearing loss patients...
June 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28515662/tempo-functionalized-c60-fullerene-deposited-on-gold-surface-for-catalytic-oxidation-of-selected-alcohols
#8
Piotr Piotrowski, Joanna Pawłowska, Jarosław Grzegorz Sadło, Renata Bilewicz, Andrzej Kaim
C60TEMPO10 catalytic system linked to a microspherical gold support through a covalent S-Au bond was developed. The C60TEMPO10@Au composite catalyst had a particle size of 0.5-0.8 μm and was covered with the fullerenes derivative of 2.3 nm diameter bearing ten nitroxyl groups; the organic film showed up to 50 nm thickness. The catalytic composite allowed for the oxidation under mild conditions of various primary and secondary alcohols to the corresponding aldehyde and ketone analogues with efficiencies as high as 79-98%, thus giving values typical for homogeneous catalysis, while retaining at the same time all the advantages of heterogeneous catalysis, e...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28513061/disorder-specific-versus-generic-cognitive-behavioral-treatment-of-anxiety-disorders-in-children-and-young-people-a-systematic-narrative-review-of-evidence-for-the-effectiveness-of-disorder-specific-cbt-compared-with-the-disorder-generic-treatment-coping-cat
#9
Rose Oldham-Cooper, Maria Loades
BACKGROUND: Coping Cat (CC), a generic cognitive-behavioral intervention for anxiety disorders in children and young people, is recommended in the United Kingdom for social anxiety disorder (SAD), generalized anxiety disorder, separation anxiety (SA), and specific phobias (SP), with disorder-specific approaches generally favored in treatment of anxiety disorders in adults. OBJECTIVES: To compare CC with disorder-specific cognitive-behavioral therapy (CBT) interventions based on anxiety-related treatment outcomes...
February 2017: Journal of Child and Adolescent Psychiatric Nursing
https://www.readbyqxmd.com/read/28511035/on-the-context-dependency-of-implicit-self-esteem-in-social-anxiety-disorder
#10
Thomas S Hiller, Melanie C Steffens, Viktoria Ritter, Ulrich Stangier
BACKGROUND AND OBJECTIVES: Cognitive models assume that negative self-evaluations are automatically activated in individuals with Social Anxiety Disorder (SAD) during social situations, increasing their individual level of anxiety. This study examined automatic self-evaluations (i.e., implicit self-esteem) and state anxiety in a group of individuals with SAD (n = 45) and a non-clinical comparison group (NC; n = 46). METHODS: Participants were randomly assigned to either a speech condition with social threat induction (giving an impromptu speech) or to a no-speech condition without social threat induction...
May 5, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28509415/ratings-of-affective-and-interpersonal-tendencies-differ-for-grandiose-and-vulnerable-narcissism-a-replication-and-extension-of-gore-widiger
#11
Courtland S Hyatt, Chelsea E Sleep, Donald R Lynam, Thomas A Widiger, W Keith Campbell, Joshua D Miller
OBJECTIVE: Theoretical conceptions of narcissism have long been characterized by two seemingly opposing poles: grandiosity and vulnerability. The goal of the current study was to investigate the extent to which traits associated with one profile are perceived to co-occur with the other within an individual. METHOD: Lay raters (n = 862; 56% female; 80% Caucasian; mean age = 37) recruited from Amazon's MTurk and assigned to one of four conditions in which they rated how often a series of narcissistic traits were displayed by a prototypical grandiose narcissist, vulnerable narcissist, a close friend, or themselves...
May 16, 2017: Journal of Personality
https://www.readbyqxmd.com/read/28508075/fast-iodide-sad-phasing-for-high-throughput-membrane-protein-structure-determination
#12
Igor Melnikov, Vitaly Polovinkin, Kirill Kovalev, Ivan Gushchin, Mikhail Shevtsov, Vitaly Shevchenko, Alexey Mishin, Alexey Alekseev, Francisco Rodriguez-Valera, Valentin Borshchevskiy, Vadim Cherezov, Gordon A Leonard, Valentin Gordeliy, Alexander Popov
We describe a fast, easy, and potentially universal method for the de novo solution of the crystal structures of membrane proteins via iodide-single-wavelength anomalous diffraction (I-SAD). The potential universality of the method is based on a common feature of membrane proteins-the availability at the hydrophobic-hydrophilic interface of positively charged amino acid residues with which iodide strongly interacts. We demonstrate the solution using I-SAD of four crystal structures representing different classes of membrane proteins, including a human G protein-coupled receptor (GPCR), and we show that I-SAD can be applied using data collection strategies based on either standard or serial x-ray crystallography techniques...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28505471/a-prospective-examination-of-risk-factors-in-the-development-of-intrusions-following-a-trauma-analog
#13
Adam J Ripley, Joshua D Clapp, J Gayle Beck
Several factors have been linked to the severity of posttraumatic distress, although retrospective designs in much of the literature limit conclusions regarding the temporal relation between risk factors and corresponding symptoms. To address these concerns, the current project employed an analog trauma paradigm to assess the impact of background characteristics, stress response, and post-stressor affect regulation on subjective distress and intrusive memories experienced during the subsequent processing of emotional stimuli...
May 5, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28504619/standard-area-diagrams-for-aiding-severity-estimation-scientometrics-pathosystems-and-methodological-trends-in-the-last-25-years
#14
Emerson Del Ponte, Sarah Jane Pethybridge, Clive Bock, Sami Jorge Michereff, Franklin Jackson Machado, Pierri Spolti
Standard area diagrams (SADs) have long been used as a tool to aid the estimation of plant disease severity, an essential variable in phytopathometry. Formal validation of SADs was not considered prior to the early 1990s, when considerable effort began to be invested developing SADs and assessing their value for improving accuracy of estimates of disease severity in many pathosystems. Peer-reviewed literature post-1990 was identified, selected and cataloged in bibliographic software for further scrutiny and extraction of scientometric, pathosystem- and methodological-related data...
May 15, 2017: Phytopathology
https://www.readbyqxmd.com/read/28504585/seven-to-11-year-olds-developing-ability-to-recognize-natural-facial-expressions-of-basic-emotions
#15
Kathleen Kang, Laura Anthoney, Peter Mitchell
Being able to recognize facial expressions of basic emotions is of great importance to social development. However, we still know surprisingly little about children's developing ability to interpret emotions that are expressed dynamically, naturally, and subtly, despite real-life expressions having such appearance in the vast majority of cases. The current research employs a new technique of capturing dynamic, subtly expressed natural emotional displays (happy, sad, angry, shocked, and disgusted). Children aged 7, 9, and 11 years (and adults) were systematically able to discriminate each emotional display from alternatives in a five-way choice...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/28503155/djinni-a-novel-technology-supported-exposure-therapy-paradigm-for-sad-combining-virtual-reality-and-augmented-reality
#16
Maher Ben-Moussa, Marius Rubo, Coralie Debracque, Wolf-Gero Lange
The present paper explores the benefits and the capabilities of various emerging state-of-the-art interactive 3D and Internet of Things technologies and investigates how these technologies can be exploited to develop a more effective technology supported exposure therapy solution for social anxiety disorder. "DJINNI" is a conceptual design of an in vivo augmented reality (AR) exposure therapy mobile support system that exploits several capturing technologies and integrates the patient's state and situation by vision-based, audio-based, and physiology-based analysis as well as by indoor/outdoor localization techniques...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28503096/affect-recognition-among-adolescents-in-therapeutic-schools-relationships-with-posttraumatic-stress-disorder-and-conduct-disorder-symptoms
#17
Shabnam Javdani, Naomi Sadeh, Geri R Donenberg, Erin Emerson, Christopher Houck, Larry K Brown
BACKGROUND: Posttraumatic stress disorder (PTSD) and conduct disorder (CD) symptoms often co-occur in adolescence, but little is known about whether they show common or distinct emotional processing deficits. METHOD: We examined the effects of PTSD and CD symptoms on facial affect processing in youth with emotional and behavior problems. Teens enrolled in therapeutic day schools (N = 371; ages 13-19) completed a structured diagnostic assessment and the Diagnostic Analysis of Nonverbal Accuracy-2 facial affect recognition task...
February 2017: Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/28502059/dynamics-of-change-in-self-reported-disability-among-persons-with-parkinson-s-disease-after-2%C3%A2-years-of-follow-up
#18
Tatjana Gazibara, Darija Kisic-Tepavcevic, Marina Svetel, Aleksandra Tomic, Iva Stankovic, Vladimir Kostic, Tatjana Pekmezovic
Symptoms of Parkinson's disease (PD) progress over time causing significant disability. Yet, change in disability over shorter time periods has not been entirely understood. The purpose of this study was to assess the Self-Assessment Disability Scale (SADS) in persons with Parkinson's disease (PD) after 2 years of follow-up and compare it with the score observed at baseline. Additionally, we aimed at evaluating association of motor and non-motor PD features at baseline with a higher disability after 2 years of follow-up...
May 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28500783/on-mixed-electron-photon-radiation-therapy-optimisation-using-the-column-generation-approach
#19
Marc-André Renaud, Monica Serban, Jan Seuntjens
PURPOSE: Despite considerable increase in the number of degrees of freedom handled by recent radiotherapy optimisation algorithms, treatments are still typically delivered using a single modality. Column generation is an iterative method for solving large optimisation problems. It is well suited for mixed-modality (e.g., photon-electron) optimisation as the aperture shaping and modality selection problem can be solved rapidly, and the performance of the algorithm scales favourably with increasing degrees of freedom...
May 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28499119/identification-of-emotions-in-mixed-disgusted-happy-faces-as-a-function-of-depressive-symptom-severity
#20
Alvaro Sanchez, Nuria Romero, Pierre Maurage, Rudi De Raedt
BACKGROUND AND OBJECTIVES: Interpersonal difficulties are common in depression, but their underlying mechanisms are not yet fully understood. The role of depression in the identification of mixed emotional signals with a direct interpersonal value remains unclear. The present study aimed to clarify this question. METHODS: A sample of 39 individuals reporting a broad range of depression levels completed an emotion identification task where they viewed faces expressing three emotional categories (100% disgusted and 100% happy faces, as well as their morphed 50% disgusted - 50% happy exemplars)...
May 5, 2017: Journal of Behavior Therapy and Experimental Psychiatry
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