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https://www.readbyqxmd.com/read/28440967/toxicity-of-cisplatin-loaded-poly-butyl-cyanoacrylate-nanoparticles-in-a-brain-cancer-cell-line-anionic-polymerization-results
#1
Nejad Mohamadi, S Maryam Kazemi, Mahshid Mohammadian, Attabak Toofani Milani, Younes Moradi, Maryam Yasemi, Meysam Ebrahimi far, Maral Mazloumi Tabrizi, Hasan Ebrahimi Shahmabadi, Azim Akbarzadeh Khiyavi
Cancer is one of the most important issues in modern medicine and the most common cause of death after cardiovascular diseases in many countries. Brain cancer is one of the most common causes of cancer death among men and women, ranking third. Chemotherapeutic drugs that aim to prevent uncontrolled proliferation of cells in tissues of the body and induce apoptosis of tumor cells are prominent candidates for development. Since cisplatin has an apoptosisinducing role, it is widely used as an anticancer agent...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28440691/n-butyl-2-cyanoacrylate-based-injectable-and-in-situ-forming-implants-for-efficient-intratumoral-chemotherapy
#2
Yanpu Wu, Luming Wang, Kaili Zhang, Lixiao Zhou, Xiaobing Zhang, Xuecheng Jiang, Chenggang Zhu
The local delivery of chemotherapeutic drugs to tumor sites is an effective approach for achieving therapeutic drug concentrations in solid tumors. Injectable implants with the ability to form in situ represent one of the most promising technologies for intratumoral chemotherapy. However, many issues must be resolved before these implants can be applied in clinical practice. Herein, we report a novel injectable in situ-forming implant system composed of n-butyl-2-cyanoacrylate (NBCA) and ethyl oleate, and the sol-gel phase transition is activated by anions in body fluids or blood...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28431005/occupational-asthma-caused-by-acrylic-compounds-from-shield-surveillance-1989-2014
#3
G I Walters, A S Robertson, V C Moore, P S Burge
Background: Acrylic monomers (acrylates), methacrylates and cyanoacrylates all cause asthma by respiratory sensitization. Occupational inhalation exposures occur across a variety of industries including health care and dental work, beauty, laboratory science, assembly and plastic moulding. Aims: To examine notifications of occupational asthma caused by acrylic compounds from a UK-based regional surveillance scheme, in order to highlight prevalent exposures and trends in presentation...
April 20, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28430334/chondro-keratoprosthesis-an-alternative-to-ookp
#4
Louis Hoffart, Laurent Guyot
PURPOSE: To evaluate the use of cartilage as a potential graft material toward osteo-odontal tissue replacement in keratoprosthesis surgery. METHODS: We describe a modification of the osteo-odonto-keratoprosthesis surgery that involves the use of autologous auricular conchal cartilage graft (ACCG). In stage 1a, a full-thickness cheek mucosa graft was performed over the ocular surface. In stage 1b, ACCG was harvested via a retroauricular approach. An optical polymethyl-methacrylate cylinder was embedded into a double-layered fragment of cartilage and secured by cyanoacrylate glue...
April 4, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28425293/cosensitized-porphyrin-system-for-high-performance-solar-cells-with-tof-sims-analysis
#5
Wenjun Wu, Huaide Xiang, Wei Fan, Jinglin Wang, Haifeng Wang, Xin Hua, Zhaohui Wang, Yi-Tao Long, He Tian, Wei-Hong Zhu
Up to date, development of organic sensitizers has been predominately focused on light harvesting, HOMO and LUMO energy levels, and electron transferring process. In contrast, their adsorption mode as well as dynamic loading behaviour onto nanoporous TiO2 is rarely considered. Herein we have employed the time of flight secondary ion mass spectrometry (TOF-SIMS) to take insight into the competitive dye adsorption mode and kinetics in cosensitized porphyrin system. Using the novel porphyrin dye FW-1 and D-A-π-A featured dye WS-5, the different bond-breaking mode in TOF-SIMS and dynamic dye-loading amount during the coadsorption process are well compared with two different anchoring groups such as benzoic acid and cyanoacrylic acid...
April 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28417279/tackers-versus-glue-mesh-fixation-an-objective-assessment-of-postoperative-acute-and-chronic-pain-using-inflammatory-markers
#6
W Liew, Y Y Wai, N R Kosai, H S Gendeh
PURPOSE: Laparoscopic hernioplasty has become a popular choice for inguinal hernia repair since its advent in 1990s. Postoperative pain is an undesirable clinical outcome impairing daily activity of 22.5% of patients. The aim of this study is to evaluate postoperative acute and chronic pain via inflammatory markers as an objective assessment following tacks or glue mesh fixation in TEP repair. METHODS: Sixty-six (66) patients with unilateral uncomplicated inguinal hernia were randomized into 34 patients in the tacker and 32 patients in cyanoacrylate glue mesh fixation in TEP repair...
April 17, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28411697/veclose-trial-12-month-outcomes-of-cyanoacrylate-closure-versus-radiofrequency-ablation-for-incompetent-great-saphenous-veins
#7
Nick Morrison, Kathleen Gibson, Michael Vasquez, Robert Weiss, Daniel Cher, Monte Madsen, Andrew Jones
OBJECTIVE: Endovenous cyanoacrylate closure (CAC) is a new U.S. Food and Drug Administration-approved therapy for treatment of clinically symptomatic venous reflux in saphenous veins. The device is indicated for the permanent closure of lower extremity superficial truncal veins, such as the great saphenous vein (GSV). Early results from a randomized trial of CAC have been reported previously. Herein we report 1-year outcomes. METHODS: There were 222 subjects with symptomatic GSV incompetence randomly assigned to receive either CAC (n = 108) or radiofrequency ablation (RFA; n = 114)...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28409733/endovascular-management-of-acute-epidural-hematomas-clinical-experience-with-80-cases
#8
Carlos Michel A Peres, Jose Guilherme M P Caldas, Paulo Puglia, Almir F de Andrade, Igor A F da Silva, Manoel J Teixeira, Eberval G Figueiredo
OBJECTIVE Small acute epidural hematomas (EDHs) treated conservatively carry a nonmeasurable risk of late enlargement due to middle meningeal artery (MMA) lesions. Patients with EDHs need to stay hospitalized for several days, with neurological supervision and repeated CT scans. In this study, the authors analyzed the safety and efficacy of the embolization of the involved MMA and associated lesions. METHODS The study group consisted of 80 consecutive patients harboring small- to medium-sized EDHs treated by MMA embolization between January 2010 and December 2014...
April 14, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28391541/oligo-p-phenylene-ethynylene-with-cyanoacrylate-terminal-groups-and-graphene-composite-as-fluorescent-chemical-sensor-for-cysteine
#9
Naoya Adachi, Mariko Yoshinari, Eri Suzuki, Mari Okada
A chemical sensor for cysteine (Cys) was fabricated based on a fluorescent oligo(p-phenylene ethynylene)s (OPEs) and OPE-graphene oxide (GO) composite. OPE with cyanoacrylate terminal groups were synthesized by a Pd-catalyzed Sonogashira coupling reaction and Knoevenagel condensation for use as a chemical sensor for Cys. The optical properties and Cys sensing capability of the cyanoacrylate modified OPE and OPE-GO composite were investigated. In addition of Cys, the fluorescence of OPE was blue-shifted and decreased (fluorescence turn-off), while the fluorescence of the OPE-GO composite was enhanced (fluorescence turn-on)...
April 8, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28388801/safety-of-2-octyl-cyanoacrylate-in-spreader-grafting
#10
Aurora G Standlee, Marc H Hohman
Cyanoacrylate adhesives can make the placement of spreader grafts in open septorhinoplasty technically easier, but its use is off-label beneath the skin. There is a theoretical risk of toxicity from cyanoacrylate breakdown products, but this risk has not been thoroughly studied in rhinoplasty. The objective was to evaluate the effects of subcutaneous cyanoacrylate use during spreader graft placement in rhinoplasty in a retrospective review of open septorhinoplasties in which 2-octyl cyanoacrylate was used to aid placement of spreader grafts...
April 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28372450/a-bronchobiliary-fistula-treated-with-cyanoacrylate-glue-in-a-patient-with-liver-cirrhosis
#11
Raúl Honrubia López, Ana Barbado Cano, Gloria Ruiz Fernández, Katherine Yelenia Bustamante Robles
A 60-year-old male was operated upon in 2002 for liver hydatidosis, which included partial right hepatectomy with cholecystectomy and bilioduodenal anastomosis. He then developed liver cirrhosis secondary to left hepatic duct stricture. He presents at the emergency room with dry cough, which he had for a month and then became associated with yellowish, bitter-tasting "fluid" expectoration. A chest-abdominal CT scan revealed a 6 x 5-cm collection roughly located somewhere between the middle pulmonary lobe and subphrenic area ...
April 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28371270/physicochemical-characterization-of-the-shell-composition-of-pbca-based-polymeric-microbubbles
#12
Lia Appold, Yang Shi, Stephan Rütten, Alexander Kühne, Andrij Pich, Fabian Kiessling, Twan Lammers
Microbubbles (MB) are routinely used as contrast agents for ultrasound (US) imaging. In recent years, MB have also attracted interest as drug delivery systems. Soft-shelled lipidic MB tend to be more advantageous for US imaging, while hard-shelled polymeric MB appear to be more suitable for drug delivery purposes because of their thicker shell and the resulting higher drug loading capacity. The physicochemical composition of the shell of polymeric MB, however, remains largely unknown. This study sets out to evaluate the molecular weight and polydispersity of the building blocks constituting the shell of poly(butyl cyanoacrylate) (PBCA) MB...
March 29, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28356686/evaluating-the-use-of-octyl-2-cyanoacrylate-in-unilateral-cleft-lip-repair
#13
Vijaylaxmy Malhotra, J K Dayashankara Rao, Varun Arya, Shalender Sharma, Sushil Singh, Payal Luthra
BACKGROUND: Facial cosmetic results are one of the most concerning issues for the parents who get their children operated for cleft lip. Moreover, the postoperative care of the surgical site, the discomfort associated with the suture removal, and additional visit for suture removal are other reasons which encourages one to use any new technologies that may replace the need for suture placement. In this study, we used octyl-2-cyanoacrylate, a tissue adhesive which offers a viable alternative to traditional techniques without compromising optimal wound closure...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28349977/photoactive-layer-based-on-t-shaped-benzimidazole-dyes-used-for-solar-cell-from-photoelectric-properties-to-molecular-design
#14
Beibei Xu, Yuanzuo Li, Peng Song, Fengcai Ma, Mengtao Sun
Three benzimidazole-based organic dyes, possessing the same triphenylamine donors and cyanoacrylic acid acceptors with the bithiophene π-bridges combined in different nuclear positions of benzimidazole, were investigated in the utility of dye-sensitizer solar cells. The structure, molecular orbital and energy, absorption spectra and some important parameters (such as light harvesting efficiency (LHE), electron injection driving force, the electron injection time, chemical reactivity parameters, vertical dipole moment as well as interaction models of dye-I2) were obtained according to Newns-Anderson model and DFT calculation...
March 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28341952/septal-deviation-treatment-using-bone-or-cartilage-grafts-fixed-with-cyanoacrylate-tissue-adhesive
#15
İrfan Özyazgan
BACKGROUND: This paper presents a method in which bone or cartilage grafts are fixed to the septal cartilage with cyanoacrylate-based tissue adhesive for the treatment of septal deviation. A prospective study was designed to show the effectiveness of the technique. METHODS: Cyanoacrylate-based tissue adhesive was used to fix the cartilage or bone grafts onto the septal cartilage to straighten deviated septal cartilage in 77 patients. Regarding the patients' preoperative and postoperative nasal respiration, the following were assessed: (1) Nasal Obstruction Symptom Evaluation (NOSE) scales, (2) patient satisfaction with postoperative nasal respiration using visual analog scoring, and (3) computerized tomographic images...
March 24, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28341499/renal-arteriovenous-malformations-a-rare-vascular-cause-of-back-pain
#16
Tazo Inui, David Frankel
OBJECTIVE: Renal arteriovenous malformation (AVM) is a very rare phenomenon (fewer than 200 cases in the literature), most commonly (75%) presenting with hematuria in young women. Renal AVMs may be cirsoid (multi-branched) or cavernous, with cirsoid morphology predominating 3:1. The historical treatment is partial nephrectomy. Best endovascular therapy is divided among many options. We present 2 cases of large renal AVMs treated with single Amplatzer plugs. METHODS: During a 2-year period (2014-15), 2 patients presented for vascular evaluation of renal AVMs found incidentally on workup for non-specific abdominal and back pain...
March 21, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28331873/rapid-corneal-thinning-and-perforated-ulcerative-keratitis-in-a-patient-with-relapsing-polychondritis
#17
Tracy Hiu Ting Lai, Nikki Far, Alvin Lerrmann Young, Vishal Jhanji
BACKGROUND: To report rapid corneal thinning and perforation in a case with relapsing polychondritis. CASE PRESENTATION: A 43 year-old male diagnosed with relapsing polychondritis suffered from bilateral scleritis, bilateral swelling of pinna, saddle nose and tracheal stenosis. The patient presented with right eye pain and redness for one month. Slit lamp examination of the right eye showed 80% peripheral corneal thinning between 3 and 7 o'clock. The best-corrected visual acuity (BCVA) was 1...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/28300259/-d-%C3%AF-a-2-%C3%AF-d-a-type-ferrocenyl-bisthiazole-linked-triphenylamine-based-molecular-systems-for-dssc-synthesis-experimental-and-theoretical-performance-studies
#18
Ramesh Maragani, Rajneesh Misra, M S Roy, Manish Kumar Singh, Ganesh D Sharma
We have designed and synthesized ferrocenyl (donor) bisthiazole linked triphenylamine (donor) based donor-π-acceptor-π-donor-acceptor (D-π-A)2-π-D-A type dyes D1 and D2 by using Pd-catalyzed Sonogashira cross-coupling and Knoevenagel condensation reactions. Their photophysical, electrochemical and computational studies reveal strong donor-acceptor interaction. Dye sensitized solar cells (DSSCs) based on D1 and D2 exhibit power conversion efficiencies (PCE) of 6.33% and 5.03%, respectively. The higher PCE value of the D1 based DSSC is attributed to its enhanced short-circuit current (Jsc) and open-circuit current (Voc) and fill factor (FF) values because of the strong binding of the anchoring cyanoacrylic acid with the TiO2 surface as compared to the dicyanovinyl unit in D2...
March 16, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28298824/comparative-evaluation-of-healing-after-periodontal-flap-surgery-using-isoamyl-2-cyanoacrylate-bioadhesive-material-and-silk-sutures-a-split-mouth-clinical-study
#19
Jyotsana Veneet Khurana, Amita Milind Mali, Rohini Salil Mali, Amit Ulhas Chaudhari
BACKGROUND: Many factors contribute to uneventful and healthy postoperative healing. Hence, closure of periodontal flap postsurgery for the attainment of primary union between flap margins is of utmost importance. Isoamyl 2-cyanoacrylate is a tissue adhesive, which can be used for the closure of elevated flaps to overcome the problems associated with conventional suture material like silk. AIM: This study aims to compare healing after periodontal flap surgery using isoamyl 2-cyanoacrylate (bioadhesive material) and silk sutures...
July 2016: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/28297690/-multiple-tentorial-dural-arteriovenous-fistulas-with-acquired-pial-arteriovenous-fistula-presented-with-unilateral-eye-symptoms-successfully-treated-by-transarterial-embolization-and-direct-surgery-a-case-report
#20
Hisato Minamide, Yutaka Hayashi, Naoyuki Uchiyama
A 58-year-old man presented with slowly progressive chemosis, exophthalmos, and blepharedema of the left eye. Digital subtraction angiography revealed multiple dural arteriovenous fistulas(dAVFs)involving the bilateral tentorium, superior sagittal sinus, and right frontal convexity. In addition, occlusion of the left cavernous sinus and left sigmoid sinus were observed, which could lead to venous hypertension and might be associated with the occurrence of multiple dAVFs. Along with the congestion of the left ophthalmic vein, increased intracranial pressure due to the left tentorial dAVF with cortical venous reflux could have caused the left eye symptoms; therefore, the tentorial lesion was treated first...
March 2017: No Shinkei Geka. Neurological Surgery
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