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Cyanoacrylate

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https://www.readbyqxmd.com/read/28538215/the-use-of-polyvinyl-alcohol-sponge-and-cyanoacrylate-glue-in-the-treatment-of-large-and-chronic-bronchopleural-fistulae-following-lung-cancer-resection
#1
Paolo Battistoni, Umberto Caterino, Sandro Batzella, Raffaele Dello Iacono, Gabriele Lucantoni, Giovanni Galluccio
BACKGROUND: Bronchopleural fistulae represent a relatively rare complication of pulmonary resection. For inoperable patients, several endoscopic procedures have been described. In the presence of large and chronic bronchopleural fistulae, persistent air leaks require a surgical therapy, while endoscopic airway stent represents a useful palliative treatment. OBJECTIVE: We describe the successful closure of large and chronic bronchopleural fistulae using an expandable polyvinyl alcohol (PVA) sponge and cyanoacrylate glue...
January 25, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28538007/a-diabetic-s-allergy-ethyl-cyanoacrylate-in-glucose-sensor-adhesive
#2
Kelly A Aschenbeck, Sara A Hylwa
No abstract text is available yet for this article.
May 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28536898/impact-of-tissue-adhesives-on-the-prevention-of-anastomotic-leakage-of-colonic-anastomoses-an-in-vivo-study
#3
Konstantinos A Vakalopoulos, Joanna W A M Bosmans, Kevin W Y van Barneveld, Ruben R M Vogels, Geesien S A Boersema, Zhouqiao Wu, Marion J J Gijbels, Johannes Jeekel, Gert-Jan Kleinrensink, Nicole D Bouvy, Johan F Lange
BACKGROUND: Tissue adhesives (TA) may be useful to strengthen colorectal anastomoses, thereby preventing anastomotic leakage (AL). Previous studies have identified cyanoacrylate (CA) TAs as the most promising colonic anastomotic sealants. This study investigates the protective effects of sealing colonic anastomoses with various CAs. MATERIALS AND METHODS: Fifty-five Wistar rats underwent laparotomy and transection of the proximal colon. An anastomosis was created with 4 interrupted sutures followed by either application of Histoacryl Flexible, Omnex, Glubran 2, or no TA seal...
May 23, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28535077/sticky-situations-cyanoacrylate-exposures-reported-to-a-poison-control-system
#4
Shaun D Carstairs, Cynthia Koh, Lily Qian, Mariam Qozi, Grant Seivard, F Lee Cantrell
INTRODUCTION: Cyanoacrylate (Super Glue(®)) exposures are commonly reported to poison control centers, but little has been published in the medical literature regarding these exposures. We sought to characterize cyanoacrylate exposures reported to a poison control system. METHODS: We performed a retrospective review of a poison system's database for all cases of single-substance human exposure to cyanoacrylate-containing products from 2005 to 2015. Data collected included age, gender, route of exposure, clinical effects, treatments recommended and medical outcome...
May 23, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28515595/percutaneous-transhepatic-techniques-for-management-of-biliary-anastomotic-strictures-in-living-donor-liver-transplant-recipients
#5
Chinmay B Kulkarni, Nirmal K Prabhu, Nazar P Kader, Ramiah Rajeshkannan, Sreekumar K Pullara, Srikanth Moorthy
AIM: To retrospectively analyze the percutaneous transhepatic techniques and their outcome in the management of biliary strictures in living donor liver transplant (LDLT) recipients. MATERIALS AND METHODS: We retrieved the hospital records of 400 LDLT recipients between 2007 and 2015 and identified 45 patients with biliary strictures. Among them, 17 patients (37.8%) (Male: female = 13:4; mean age, 36.1 ± 17.5 years) treated by various percutaneous transhepatic biliary techniques alone or in combination with endoscopic retrograde cholangiopancreatography (ERCP) were included in the study...
January 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28502685/transorbital-glue-embolization-of-a-recurrent-venous-varix-using-real-time-image-guidance-in-the-neuroangiography-suite
#6
Sophia F Shakur, Denise Brunozzi, Pete Setabutr, Ahmed E Hussein, Fady T Charbel, Ali Alaraj
Orbital lesions are challenging to access due to their location amidst critical anatomical structures. Here, we demonstrate direct transorbital cannulation of an orbital venous varix using image guidance. A 36-year-old male was diagnosed to have a left orbital venous varix approximately 5 years ago at an outside institution. He subsequently underwent surgery for direct intraoperative embolization of the venous varix followed by surgical resection. The patient recently presented to us with left eye pain, proptosis, double vision, and conjunctival hemorrhage precipitated by straining or lying flat...
May 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28497818/new-d-d-%C3%AF-a-triphenylamine-coumarin-sensitizers-for-dye-sensitized-solar-cells
#7
Ji He, Yang Liu, Jianrong Gao, Liang Han
Three D-D-π-A triphenylamine-coumarin sensitizers were designed and synthesized with a triphenylamine and coumarin double donor and a cyanoacrylic acid acceptor. Thiophene, bithiophene and phenylthiophene were used as π-bridges, respectively, and the effects of different π-bridges on the photophysical properties and photovoltaic performance were investigated. With the incorporation of an additional thiophene unit, the bithiophene π-bridge contributes to better light absorption and hence superior JSC compared with the thiophene π-bridge...
May 12, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28494022/the-effect-of-biological-sealants-and-adhesive-treatments-on-matrix-metalloproteinase-expression-during-renal-injury-healing
#8
José Miguel Lloris-Carsí, Carlos Barrios, Beatriz Prieto-Moure, José Miguel Lloris-Cejalvo, Dolores Cejalvo-Lapeña
BACKGROUND: Renal injuries are relatively common in cases of abdominal trauma. Adhesives and sealants can be used to repair and preserve damaged organs. Using a rat model, this study explores the activity of different matrix metalloproteinases (MMP) during the healing of renal injuries treated by two biological adhesives (TachoSil and GelitaSpon) and a new synthetic elastic cyanoacrylate (Adhflex). METHODS: Renal traumatic injuries were experimentally induced in 90 male Wistar rats by a Stiefel Biopsy Punch in the anterior aspect of the left kidney...
2017: PloS One
https://www.readbyqxmd.com/read/28488103/a-case-of-common-peroneal-nerve-palsy-associated-with-internal-iliac-artery-embolization-by-using-n-butyl-2-cyanoacrylate-nbca
#9
Keishi Fujiwara, Yukihisa Ogawa, Kenji Murakami, Yasunori Arai, Hiroshi Nishimaki, Hidefumi Mimura, Yasuo Nakajima
A 64-year-old man was scheduled to undergo endovascular aneurysm repair for an abdominal aortic aneurysm (AAA). Since preoperative computed tomography showed an AAA with common iliac artery and internal iliac artery (IIA) aneurysms, IIA embolization was scheduled. Embolization using a coil was supposed to be performed; however, the lateral sacral artery could not be selected. For this reason, IIA embolization using N-butyl-2-cyanoacrylate (NBCA) was undertaken. During embolization, the median sacral artery was unexpectedly embolized through the lateral sacral artery...
May 9, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28483692/biocompatible-nanostructured-solid-adhesives-for-biological-soft-tissues
#10
Masahiro Okada, Akira Nakai, Emilio Satoshi Hara, Tetsushi Taguchi, Takayoshi Nakano, Takuya Matsumoto
Over the past few years, the development of novel adhesives for biological soft tissue adhesion has gained significant interest. Such adhesives should be non-toxic and biocompatible. In this study, we synthesized a novel solid adhesive using nanostructured hydroxyapatite (HAp) and evaluated its physical adhesion properties through in vitro testing with synthetic hydrogels and mice soft tissues. The results revealed that the HAp-nanoparticle dispersions and HAp-nanoparticle-assembled nanoporous plates showed efficient adhesion to the hydrogels...
May 5, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28481657/enhanced-oral-bioavailability-of-10-hydroxycamptothecin-through-the-use-of-poly-n-butyl-cyanoacrylate-nanospheres
#11
Xin Jin, Sajid Asghar, Xieting Zhu, Zhipeng Chen, Junhong Liu, Yibo Li, Hongying Li, Qineng Ping, Yanyu Xiao
The article describes the preparation, physicochemical characterization, drug release, and in vivo behavior of 10-hydroxycamptothecin-loaded poly (n-butyl cyanoacrylate) nanospheres (HCPT-PBCA-NSs). HCPT-PBCA-NSs were successfully prepared via emulsion polymerization of n-butyl cyanoacrylate (BCA) monomer in acidic medium with the aid of two colloidal stabilizers (Poloxamer 188 and Dextran 70). The influence of pH, the time of polymerization, and the dosage of the drug on particle size and encapsulation efficiency (EE) were studied...
May 8, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28465402/a-systematic-characterization-of-the-factors-influencing-polymerization-and-dynamic-behavior-of-n-butyl-cyanoacrylate
#12
Bill H Wang, Melfort Boulton, Donald H Lee, David M Pelz, Stephen P Lownie
INTRODUCTION: Brain arteriovenous malformations are abnormal connections between arteries and veins without an intervening capillary bed. Endovascular glue embolization with N-butyl cyanoacrylate (NBCA) is an accepted form of treatment. The reported complication rates vary widely from 2% to 15%, and timing of polymerization appears to play a major role. Additionally, the interaction between NBCA and vessel surface as well as the presence of biological catalysts are poorly understood. METHODS: Polymerization time was measured for mixtures of Lipiodol/NBCA of 50/50, 70/30, and 60/40...
May 2, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28462783/cryptogenic-hemoptysis-effectiveness-of-bronchial-artery-embolization-using-n-butyl-cyanoacrylate
#13
Hyukjoon Lee, Chang Jin Yoon, Nak Jong Seong, Chang Ho Jeon, Ho Il Yoon, Joongseok Go
PURPOSE: To describe angiographic findings and assess safety and effectiveness of bronchial artery embolization (BAE) with N-butyl cyanoacrylate (NBCA) in patients with cryptogenic hemoptysis (CH). MATERIALS AND METHODS: Between May 2003 and March 2014, 26 patients who underwent BAE for CH were enrolled. A retrospective review was conducted for angiographic findings and clinical outcomes of BAE, including technical and clinical success, complications, and recurrent hemoptysis...
April 25, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28460205/cyanoacrylate-sealant-compared-to-fibrin-glue-in-staple-line-reinforcement-during-laparoscopic-sleeve-gastrectomy-pilot-prospective-observational-study
#14
G Martines, R Digennaro, M De Fazio, P Capuano
Laparoscopic Sleeve Gastrectomy (LSG) is associated with serious complications, such as staple line leaks and bleeding. This paper presents a novel approach aimed at the successful consolidation of the suture by the use of the cyanoacrylate, here compared to the use of fibrin glue. Fifty consecutive patients, recruited from October 2015 to March 2016, were submitted to laparoscopic sleeve gastrectomy by standardized surgical technique. The staple line was reinforced with cyanoacrylate or fibrin glue. There were no post-operative complications and no operative time prolongation...
January 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28455206/mucoadhesive-properties-of-low-molecular-weight-chitosan-or-glycol-chitosan-and-corresponding-thiomer-coated-poly-isobutylcyanoacrylate-core-shell-nanoparticles
#15
Claudio Palazzo, Giuseppe Trapani, Gilles Ponchel, Adriana Trapani, Christine Vauthier
The aim of the present work was to evaluate the mucoadhesive properties of poly(isobutyl cyanoacrylate) (PIBCA) nanoparticles (NPs) coated with Low Molecular Weight (LMW) chitosan (CS)- and glycol chitosan (GCS)-based thiomers as well as with the corresponding LMW unmodified polysaccharides. For this purpose, all the CS- and GCS-based thiomers were prepared under simple and mild conditions starting from the LMW unmodified polymers CS and GCS. The resulting NPs were of spherical shape with diameters ranging from 400 to 600 nm and 187 to 309 nm, for CS- and GCS-based NPs, respectively...
April 25, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28454918/targeting-leishmania-amazonensis-amastigotes-through-macrophage-internalisation-of-a-hydroxymethylnitrofurazone-nanostructured-polymeric-system
#16
Lis Marie Monteiro, Raimar Löbenberg, Elizabeth Igne Ferreira, Paulo Cesar Cotrim, Edite Kanashiro, Mussya Rocha, Chung Man Chin, Nadia Bou-Chacra
Dextran-coated poly (n-butyl cyanoacrylate) nanoparticles (PBCA-NPs) were prepared and were evaluated for enhanced delivery of a promising anti-Leishmania drug candidate, hydroxymethylnitrofurazone (NFOH), to phagocytic cells. Currently available chemotherapy for leishmaniasis, such as pentavalent antimonials, presents low safety and efficacy. Furthermore, widespread drug resistance in leishmaniasis is rapidly emerging. To overcome these drawbacks, the use of nanosized delivery systems can reduce systemic drug toxicity and increase the drug concentration in infected macrophages, therefore improving treatment of leishmaniasis...
April 25, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28451467/skin-protectants-made-of-curable-polymers-effect-of-application-on-local-skin-temperature
#17
Michael J Walt, Nancy Atwood, Stéphanie F Bernatchez, Bruce P Ekholm, Robert Asmus
Objective: To measure the skin temperature after application of a new skin protectant intended for incontinence-associated dermatitis (IAD), compared with a commercial product with an analogous cyanoacrylate-based chemistry. Approach: Twelve healthy human volunteers received an application of the new product on one thigh and of the comparator on the other thigh. An infrared camera using ThermaCAM™ software imaged the skin and measured the temperature at the skin surface over time to characterize the thermal cure profile induced by the products on the skin...
April 1, 2017: Advances in Wound Care
https://www.readbyqxmd.com/read/28445368/correcting-concavity-of-rabbit-auricular-cartilage-comparison-of-single-scoring-incisions-with-butyl-cyanoacrylate-aided-techniques
#18
Yalcin Yontar, İrfan Özyazgan
BACKGROUND: The authors present the results of an experimental study in which four different techniques were used for the correction of concave rabbit auricular cartilage. METHODS: Sixteen New Zealand adult male rabbits were used in the study. Butyl cyanoacrylate-aided cartilage graft fixation and butyl cyanoacrylate-aided bone graft fixation and scoring technique, alone or combined with butyl cyanoacrylate application, were performed to correct the concavity of rabbit auricular cartilage...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28440967/toxicity-of-cisplatin-loaded-poly-butyl-cyanoacrylate-nanoparticles-in-a-brain-cancer-cell-line-anionic-polymerization-results
#19
Nejad Mohamadi, S Maryam Kazemi, Mahshid Mohammadian, Attabak Toofani Milani, Younes Moradi, Maryam Yasemi, Meysam Ebrahimi far, Maral Mazloumi Tabrizi, Hasan Ebrahimi Shahmabadi, Azim Akbarzadeh Khiyavi
Cancer is one of the most important issues in modern medicine and the most common cause of death after cardiovascular diseases in many countries. Brain cancer is one of the most common causes of cancer death among men and women, ranking third. Chemotherapeutic drugs that aim to prevent uncontrolled proliferation of cells in tissues of the body and induce apoptosis of tumor cells are prominent candidates for development. Since cisplatin has an apoptosisinducing role, it is widely used as an anticancer agent...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28440691/n-butyl-2-cyanoacrylate-based-injectable-and-in-situ-forming-implants-for-efficient-intratumoral-chemotherapy
#20
Yanpu Wu, Luming Wang, Kaili Zhang, Lixiao Zhou, Xiaobing Zhang, Xuecheng Jiang, Chenggang Zhu
The local delivery of chemotherapeutic drugs to tumor sites is an effective approach for achieving therapeutic drug concentrations in solid tumors. Injectable implants with the ability to form in situ represent one of the most promising technologies for intratumoral chemotherapy. However, many issues must be resolved before these implants can be applied in clinical practice. Herein, we report a novel injectable in situ-forming implant system composed of n-butyl-2-cyanoacrylate (NBCA) and ethyl oleate, and the sol-gel phase transition is activated by anions in body fluids or blood...
November 2017: Drug Delivery
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