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Prostate specific antigen, bph

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https://www.readbyqxmd.com/read/28208224/percent-decrease-of-serum-prostate-specific-antigen-after-dutasteride-administration-is-equivalent-in-men-with-clinical-benign-prostatic-hyperplasia-having-baseline-prostate-specific-antigen-10-ng-ml-and-those-having-baseline-prostate-specific-antigen-2-5-10
#1
Hideki Takeshita, Satoru Kawakami, Akihiro Yano, Yohei Okada, Makoto Morozumi, Takumi Yamada
No abstract text is available yet for this article.
February 16, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28168057/biomarkers-of-prostatic-cancer-an-attempt-to-categorize-patients-into-prostatic-carcinoma-benign-prostatic-hyperplasia-or-prostatitis-based-on-serum-prostate-specific-antigen-prostatic-acid-phosphatase-calcium-and-phosphorus
#2
Shahana Sarwar, Mohammed Abdul Majid Adil, Parveen Nyamath, Mohammed Ishaq
Prostatitis, BPH, and P.Ca are the most frequent pathologies of the prostate gland that are responsible for morbidity in men. Raised levels of PSA are seen in different pathological conditions involving the prostate. PAP levels are altered in inflammatory or infectious or abnormal growth of the prostate tissue. Serum calcium and phosphorus levels were also found to be altered in prostate cancer and BPH. The present study was carried out to study the levels of PSA, PAP, calcium, and phosphorus in serum of patients with Prostatitis, BPH, or P...
2017: Prostate Cancer
https://www.readbyqxmd.com/read/28160568/serum-ferritin-in-combination-with-prostate-specific-antigen-improves-predictive-accuracy-for-prostate-cancer
#3
Xijuan Wang, Peng An, Jiling Zeng, Xiaoyan Liu, Bo Wang, Xuexian Fang, Fudi Wang, Guoping Ren, Junxia Min
Ferritin is highly expressed in many cancer types. Although a few studies have reported an association between high serum ferritin levels and an increased risk of prostate cancer, the results are inconsistent. Therefore, we performed a large case-control study consisting of 2002 prostate cancer patients and 951 control patients with benign prostatic hyperplasia (BPH). We found that high ferritin levels were positively associated with increased serum prostate-specific antigen (PSA) levels and prostate cancer risk; each 100 ng/ml increase in serum ferritin increased the odds ratio (OR) by 1...
February 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28138409/the-standards-of-an-ultrasound-examination-of-the-prostate-gland-part-1
#4
REVIEW
Janusz F Tyloch, Andrzej Paweł Wieczorek
The article discusses the principles of the proper performance of the ultrasound examination of the prostate gland. The paper has been divided into two parts: the general one and the detailed one. The first part presents the necessary requirements referring to the ultrasound apparatus for performing transabdominal examinations of the urinary bladder and the prostate gland as well as for transrectal examinations of the prostate gland. The paper also describes the techniques of performing both examinations together with the methods of measuring the capacity of the urinary bladder and the volume of the prostate gland...
December 2016: Journal of Ultrasonography
https://www.readbyqxmd.com/read/28134773/wisteria-floribunda-agglutinin-and-its-reactive-glycan-carrying-prostate-specific-antigen-as-a-novel-diagnostic-and-prognostic-marker-of-prostate-cancer
#5
Kazuhisa Hagiwara, Yuki Tobisawa, Takatoshi Kaya, Tomonori Kaneko, Shingo Hatakeyama, Kazuyuki Mori, Yasuhiro Hashimoto, Takuya Koie, Yoshihiko Suda, Chikara Ohyama, Tohru Yoneyama
Wisteria floribunda agglutinin (WFA) preferably binds to LacdiNAc glycans, and its reactivity is associated with tumor progression. The aim of this study to examine whether the serum LacdiNAc carrying prostate-specific antigen-glycosylation isomer (PSA-Gi) and WFA-reactivity of tumor tissue can be applied as a diagnostic and prognostic marker of prostate cancer (PCa). Between 2007 and 2016, serum PSA-Gi levels before prostate biopsy (Pbx) were measured in 184 biopsy-proven benign prostatic hyperplasia patients and 244 PCa patients using an automated lectin-antibody immunoassay...
January 26, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28117495/elevated-serum-psa-is-associated-with-human-herpesvirus-8-infection-and-increased-circulating-cytokine-levels-in-men-from-tobago
#6
Jill D Henning, Jaideep M Karamchandani, Luis A Bonachea, Clareann H Bunker, Alan L Patrick, Frank J Jenkins
BACKGROUND: Serum-prostate specific antigen (PSA) levels have been used for many years as a biomarker for prostate cancer. This usage is under scrutiny due to the fact that elevated PSA levels can be caused by other conditions such as benign prostatic hyperplasia and infections of or injury to the prostate. As a result, the identification of specific pathogens capable of increasing serum levels of PSA is important. A potential candidate responsible for elevated PSA is human herpesvirus 8 (HHV-8)...
January 24, 2017: Prostate
https://www.readbyqxmd.com/read/28110318/genetic-variation-of-the-psca-gene-rs2294008-is-not-associated-with-the-risk-of-prostate-cancer
#7
Lee Il-Seok, Pil Seo Sung, Sok Ha Yun, Jeong Pildu, Won Kang Ho, Tae Kim Won, Kim Yong-June, Joong Yun Seok, Cheol Lee Sang, Kim Wun-Jae
Prostate stem cell antigen (PSCA) is a cell-membrane glycoprotein consisting of 123 amino acids and highly expressed in the prostate, but there have been few reports on the relationship between rs2294008 of PSCA and prostate cancer in the literature. Therefore, we evaluated the association between rs2294008 and the risk of prostate cancer. A total of 240 prostate cancer patients and 306 controls (patients with benign prostatic hyperplasia) were enrolled. Genotype analysis of rs2294008 of PSCA was performed using PCR...
January 19, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28073286/bipolar-plasmakinetic-enucleo-resection-of-the-prostate-our-exp%C3%A3-rience-with-245-patients-for-3-years-of-follow-up
#8
Ahmed Abou-Taleb, Waleed El-Shaer, Wael Saber, Tarek Gharib, Alaa Elshaer
OBJECTIVE: the aim of this study was to evaluate the safety, feasibility and effectiveness of bipolar transurethral plasmakinetic enucleation of the prostate (PKEP). PATIENTS AND METHOD: Between January 2010 and October 2013, 245 patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) underwent transurethral enucleation of prostate using bipolar plasma vaporization energy. They were evaluated pre-operatively by Full detailed history, examination especially digital rectal examination (DRE), routine pre-operative investigation, serum prostate-specific antigen (PSA), abdominal and trans-rectal ultrasonography (US) and Maximum flow rates (Qmax)...
January 10, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28043110/obesity-as-a-risk-factor-for-prostatic-enlargement-a-retrospective-cohort-study-in-korea
#9
Jae Hung Jung, Song Vogue Ahn, Jae Mann Song, Se-Jin Chang, Kwang Jin Kim, Sung Won Kwon, Sang-Yoo Park, Sang-Baek Koh
PURPOSE: We aimed to evaluate obesity, a risk factor of metabolic syndrome, and its association with prostatic enlargement in a retrospective cohort in Korea. METHODS: Baseline data were obtained from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population (KoGES-ARIRANG). Between March 2015 and November 2015, 2,127 male participants of KoGES-ARIRANG were invited to the Korean Prostate Health Council Screening Program, and 602 participants underwent urological examination, including serum prostate specific antigen measurement and transrectal ultrasonography, and completed the International Prostate Symptom Score questionnaire...
December 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/28043105/association-study-of-polymorphisms-of-epidermal-growth-factor-and-epidermal-growth-factor-receptor-with-benign-prostatic-hyperplasia-in-a-korean-population
#10
Su Kang Kim, Hyun Kyung Park, Han Sung Choi, Koo Han Yoo, Joo-Ho Chung
PURPOSE: Recent studies have suggested that specific single-nucleotide polymorphisms (SNPs) contribute to the clinical features of benign prostatic hyperplasia (BPH). In this study, we investigated the relationships of genetic polymorphisms of the epidermal growth factor (EGF) gene and the epidermal growth factor receptor (EGFR) gene with BPH. METHODS: A total of 218 patients with BPH were enrolled in this study. We evaluated the relationship between eight SNPs in the EGF and EGFR genes and prostate volume, prostate-specific antigen (PSA), and International Prostate Symptom Score of BPH patients...
December 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/28043104/long-term-combination-therapy-with-%C3%AE-blockers-and-5%C3%AE-reductase-inhibitors-in-benign-prostatic-hyperplasia-patient-adherence-and-causes-of-withdrawal-from-medication
#11
Hueih Ling Ong, Chun-Hou Liao, Hann-Chorng Kuo
PURPOSE: To investigate long-term therapeutic effects and patient adherence to a combination therapy of a 5α-reductase inhibitor and an α-blocker and to identify causes of withdrawal from medication in patients with clinical benign prostatic hyperplasia (BPH). METHODS: BPH patients with lower urinary tract symptoms (LUTS) receiving combination therapy with follow-ups for 1-12 years were retrospectively analyzed. Therapeutic effects were assessed at baseline and annually by measuring International Prostatic Symptoms Score, quality of life index, total prostate volume (TPV), maximal flow rate, voided volume, postvoid residual volume and prostate-specific antigen level...
December 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/28042794/effect-of-onabotulinum-toxin-type-a-intraprostatic-injection-on-the-outcome-of-benign-prostatic-hyperplasia-patients-refractory-to-medical-therapy-a-2-year-follow-up-study
#12
Tiago Gorgal Rodrigues de Carvalho, Rui Pinto, Francisco Cruz, João Silva
OBJECTIVES: To determine the outcome of Benign Prostatic Hyperplasia patients refractory to standard medical therapy and with significant comorbidities submitted to intraprostatic injection of onabotulinum toxin A. METHODS: Thirty-seven patients with symptomatic Benign Prostatic Hyperplasia refractory to medical therapy who were poor candidates for surgical treatment were enrolled. All patients voided spontaneously. They received one single transrectal application of 200 U of onabotulinum toxin A...
December 2016: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28008272/different-levels-of-serum-micrornas-in-prostate-cancer-and-benign-prostatic-hyperplasia-evaluation-of-potential-diagnostic-and-prognostic-role
#13
Giovanni Cochetti, Giulia Poli, Gabriella Guelfi, Andrea Boni, Maria Giulia Egidi, Ettore Mearini
INTRODUCTION: Diagnosis of prostate cancer (PCa) is based on prostate biopsy that is performed when prostate specific antigen (PSA) is persistently altered over time and/or abnormal digital rectal examination is found. Serum PSA levels increase in both PCa and benign prostatic hyperplasia, leading to an increased number of unnecessary biopsies. There is an urgent need to unravel PCa-specific molecular signatures. PATIENTS AND METHODS: This study aimed at characterizing a panel of circulating micro RNAs (miRNAs) that could distinguish PCa from benign prostatic hyperplasia in a population of age-matched patients with increased PSA levels...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27998216/biases-in-recommendations-for-and-acceptance-of-prostate-biopsy-significantly-affect-assessment-of-prostate-cancer-risk-factors-results-from-two-large-randomized-clinical-trials
#14
Catherine M Tangen, Phyllis J Goodman, Cathee Till, Jeannette M Schenk, M Scott Lucia, Ian M Thompson
Purpose To identify factors related to who undergoes a prostate biopsy in a screened population and to estimate the impact of biopsy verification on risk factor-prostate cancer associations. Patients and Methods Men who were screened regularly from the placebo arms of two large prostate cancer prevention trials (Prostate Cancer Prevention Trial [PCPT] and Selenium and Vitamin E Cancer Prevention Trial [SELECT]) were examined to define incident prostate cancer cohorts. Because PCPT had an end-of-study biopsy, prostate cancer cases were categorized by a preceding prostate-specific antigen/digital rectal examination prompt (yes/no) and noncases by biopsy-proven negative status (yes v no)...
December 20, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27956935/an-analytical-study-of-prostate-specific-antigen-dynamics
#15
Ernesto P Esteban, Giovanni Deliz, Jaileen Rivera-Rodriguez, Stephanie M Laureano
The purpose of this research is to carry out a quantitative study of prostate-specific antigen dynamics for patients with prostatic diseases, such as benign prostatic hyperplasia (BPH) and localized prostate cancer (LPC). The proposed PSA mathematical model was implemented using clinical data of 218 Japanese patients with histological proven BPH and 147 Japanese patients with LPC (stages T2a and T2b). For prostatic diseases (BPH and LPC) a nonlinear equation was obtained and solved in a close form to predict PSA progression with patients' age...
2016: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/27956827/efficacy-and-safety-of-prostate-artery-embolization-on-lower-urinary-tract-symptoms-related-to-benign-prostatic-hyperplasia-a-systematic-review-and-meta-analysis
#16
REVIEW
Xiao-Yan Wang, Huan-Tao Zong, Yong Zhang
BACKGROUND: Prostate artery embolization (PAE) is emerging and is a promising minimally invasive therapy that improves lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH). The purpose of this article was to evaluate the efficacy and safety of PAE on LUTS related to BPH. MATERIALS AND METHODS: A literature review was performed to identify all published articles of PAE for BPH. The sources included MEDLINE, EMBASE and Cochrane Library from 1980 to 2016...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27941343/detection-of-prostate-cancer-metastasis-by-whole-body-magnetic-resonance-imaging-combined-with-bone-scintigraphy-and-psa-levels
#17
Hengqing An, Ning Tao, Jia Li, Yonghui Guan, Wenguang Wang, Yujie Wang, Feng Wang
BACKGROUND/AIMS: The combined role of whole-body magnetic resonance imaging (WB-MRI), bone scintigraphy and prostate specific antigen (PSA) were considered in predicting metastases and prognosis of prostate cancer (PCa). METHODS: Totally 38 PCa patients underwent WB-MRI, bone scintigraphy and PSA detections, and 34 benign prostate hyperplasia (BPH) patients were checked with PSA. Pearson correlations were performed to determine associations among PSA, apparent diffusion coefficient (ADC) and Gleason scoring...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27932164/retzius-space-preservation-technique-for-robotic-assisted-laparoscopic-radical-prostatectomy-in-a-kidney-transplant-patient-first-case-in-thailand-and-our-first-experience
#18
P Jenjitranant, P Sangkum, P Sirisreetreerux, W Viseshsindh, S Patcharatrakul, W Kongcharoensombat
OBJECTIVE: The aim of this work was to report our experience in robotic-assisted laparoscopic radical prostatectomy for the treatment of localized prostate cancer in a kidney transplant recipient. METHODS: A 73-year-old man with chronic renal failure underwent living-donor kidney transplantation (KT) in 1993. His baseline creatinine after KT was ∼1.2 mg/dL. He developed lower urinary tract symptoms in 1999. He was diagnosed with benign prostatic hyperplasia and treated accordingly...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27928815/comparing-monotherapy-with-tadalafil-or-tamsulosin-and-their-combination-therapy-in-men-with-benign-prostatic-hyperplasia-a-randomized-clinical-trial
#19
Hossein Karami, Amin Hassanzadeh-Hadad, Morteza Fallah-Karkan
PURPOSE: To compare monotherapy with tadalafil or tamsulosin and their combination therapy in men with benignprostatic hyperplasia and erectile dysfunction by comparing IPSS score, prostate volume and Qmax and someother outcomes. MATERIALS AND METHODS: This randomized, single-blind, paralleled group clinical trial was done in 2013 on patientswho had referred to our hospital in Tehran. All patients with lower urinary tract symptoms, benign prostatichyperplasia and any grade of erectile dysfunction were recruited...
8, 2016: Urology Journal
https://www.readbyqxmd.com/read/27928444/the-remote-effects-of-intravitreal-anti-vegf-therapy
#20
Balta F, Merticariu M, Taban C, Neculau G, Merticariu A, Muresanu D, Badescu D, Jinga V
Objective: To study the effects of intravitreal anti-Vascular Endothelial Growth Factor (VEGF) therapy with Avastin for wet Age-Related Macular Degeneration (AMD) on Benign Prostatic Hyperplasia (BPH)-related symptoms. Methods: An exploratory trial was conducted from August 1, 2013 to February 1, 2014, that included 14 male patients previously diagnosed with BPH, who were aged between 59 and 69 years. The trial was performed in Bucharest and involved two medical institutions: the Clinical Hospital of Eye Emergencies and the "Prof...
October 2016: Journal of Medicine and Life
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