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https://www.readbyqxmd.com/read/29344005/biological-clocks-their-relevance-to-immune-allergic-diseases
#1
REVIEW
Roberto Paganelli, Claudia Petrarca, Mario Di Gioacchino
The 2017 Nobel Prize for Physiology or Medicine, awarded for the discoveries made in the past 15 years on the genetic and molecular mechanisms regulating many physiological functions, has renewed the attention to the importance of circadian rhythms. These originate from a central pacemaker in the suprachiasmatic nucleus in the brain, photoentrained via direct connection with melanopsin containing, intrinsically light-sensitive retinal ganglion cells, and it projects to periphery, thus creating an inner circadian rhythm...
2018: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29343226/binge-eating-disorder-and-depressive-symptoms-among-females-of-child-bearing-age-the-korea-nurses-health-study
#2
O Kim, M S Kim, J Kim, J E Lee, H Jung
BACKGROUND: Most studies regarding the relationship between binge eating disorder (BED) and depression have targeted obese populations. However, nurses, particularly female nurses, are one of the vocations that face these issues due to various reasons including high stress and shift work. This study investigated the prevalence of BED and the correlation between BED and severity of self-reported depressive symptoms among female nurses in South Korea. METHODS: Participants were 7,267 female nurses, of which 502 had symptoms of BED...
January 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29324693/inhibiting-the-physiological-stress-effects-of-a-sustained-attention-task-on-shoulder-muscle-activity
#3
Fiona Wixted, Cliona O'Riordan, Leonard O'Sullivan
OBJECTIVE: The objective of this study was to investigate if a breathing technique could counteract the effects of hyperventilation due to a sustained attention task on shoulder muscle activity. BACKGROUND: The trend towards higher levels of automation in industry is increasing. Consequently, manufacturing operators often monitor automated process for long periods of their work shift. Prolonged monitoring work requires sustained attention, which is a cognitive process that humans are typically poor at and find stressful...
January 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29323199/observation-of-carrier-localization-in-cubic-crystalline-ge2sb2te5-by-field-effect-measurement
#4
Hang Qian, Hao Tong, Ming-Ze He, Hong-Kai Ji, Ling-Jun Zhou, Ming Xu, Xiang-Shui Miao
The tunable disorder of vacancies upon annealing is an important character of crystalline phase-change material Ge2Sb2Te5 (GST). A variety of resistance states caused by different degrees of disorder can lead to the development of multilevel memory devices, which could bring a revolution to the memory industry by significantly increasing the storage density and inspiring the neuromorphic computing. This work focuses on the study of disorder-induced carrier localization which could result in multiple resistance levels of crystalline GST...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29318587/new-perspectives-on-the-role-of-melatonin-in-human-sleep-circadian-rhythms-and-their-regulation
#5
REVIEW
N Zisapel
In mammals a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24h light-dark cycle to invigorate and optimize the internal temporal order. The SCN-activated, light- inhibited production of melatonin conveys the message of darkness to the clock and induces night state in physiological function, e.g., sleep/wake blood pressure and metabolism. Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in disorders associated with diminished or misaligned melatonin rhythms, e...
January 10, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29316800/pro-dopamine-regulator-kb220z-attenuates-hoarding-and-shopping-behavior-in-a-female-diagnosed-with-sud-and-adhd
#6
Thomas McLaughlin, Kenneth Blum, Bruce Steinberg, Edward J Modestino, Lyle Fried, David Baron, David Siwicki, Eric R Braverman, Rajendra D Badgaiyan
Background Addictive-like behaviors (e.g., hoarding and shopping) may be the result of the cumulative effects of dopaminergic and other neurotransmitter genetic variants as well as elevated stress levels. We, therefore, propose that dopamine homeostasis may be the preferred goal in combating such challenging and unwanted behaviors, when simple dopaminergic activation through potent agonists may not provide any resolution. Case presentation C.J. is a 38-year-old, single, female, living with her mother. She has a history of substance use disorder as well as attention deficit hyperactivity disorder, inattentive type...
January 10, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29313407/sense-of-coherence-smoking-status-biochemical-cardiovascular-risk-factors-and-body-mass-in-blue-collar-workers-short-report
#7
Anna Najder
The crucial cause of cardiovascular disorders is atherosclerosis developed by abnormal cholesterols levels or disorders affecting blood glucose. One of the best-known cardiovascular risk factors is also tobacco smoking. Simultaneously, sense of coherence (SoC) as a personal resource motivating to managing one's own health behaviors, such as avoiding tobacco smoking, was reported to be protective against coronary heart disease. Such association was observed in white-collar workers but not in blue-collar workers...
January 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29310003/resilience-as-a-moderating-factor-between-stress-and-alcohol-related-consequences-in-the-army-national-guard
#8
Jessica Kelley Morgan, Janice Brown, Robert M Bray
Due to the current prolonged conflicts in Iraq and Afghanistan, members of the United States National Guard and Reserve have shifted from a historically support-based role to an integral segment of combat efforts. Clinical and epidemiological research studies conducted on both civilian and military populations have documented high rates of comorbidity of stress disorders and substance use disorders. It is widely understood that excessive alcohol use is an issue among military personnel. The aim of this paper is to describe risk factors for alcohol-related serious consequences in a study of Army National Guard service members, as well as the role of resilience in protecting against these risks...
January 2, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29309770/a-sub-set-of-psychoactive-effects-may-be-critical-to-the-behavioral-impact-of-ketamine-on-cocaine-use-disorder-results-from-a-randomized-controlled-laboratory-study
#9
REVIEW
E Dakwar, E V Nunes, C L Hart, M C Hu, R W Foltin, F R Levin
Efforts to translate sub-anesthetic ketamine infusions into widespread clinical use have centered around developing medications with comparable neurobiological activity, but with attenuated psychoactive effects so as to minimize the risk of behavioral toxicity and abuse liability. Converging lines of research, however, suggest that some of the psychoactive effects of sub-anesthetic ketamine may have therapeutic potential. Here, we assess whether a subset of these effects - the so-called mystical-type experience - mediates the effect of ketamine on craving and cocaine use in cocaine dependent research volunteers...
January 5, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29308221/cognitive-bias-modification-for-facial-interpretation-a-randomized-controlled-trial-of-transfer-to-self-report-and-cognitive-measures-in-a-healthy-sample
#10
S E Peters, J Lumsden, O H Peh, I S Penton-Voak, M R Munafò, O J Robinson
Cognitive bias modification is a potential low-intensity intervention for mood disorders, but previous studies have shown mixed success. This study explored whether facial interpretation bias modification (FIBM), a similar paradigm designed to shift emotional interpretation (and/or perception) of faces would transfer to: (i) self-reported symptoms and (ii) a battery of cognitive tasks. In a preregistered, double-blind randomized controlled trial, healthy participants received eight online sessions of FIBM (N = 52) or eight sham sessions (N = 52)...
December 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29307158/relationship-between-sleep-quality-obstructive-sleep-apnea-and-sleepiness-during-day-with-related-factors-in-professional-drivers
#11
Samira Joorabbaf Motlagh, Maryam Shabany, Khosro Sadeghniiat Haghighi, Alireza Nikbakht Nasrabadi, Seyed Hassan Emami Razavi
One of the important reasons for accidents is sleepiness.With this description, the sleep disorders are associated with health and mortality, and not only affect the person but also the family and the whole society. Aim of this study was assessing of relationship between Sleep Quality, Obstructive sleep Apnea and Sleepiness during day with related factors in professional drivers. This was a cross-sectional study measuring correlation between sleep quality questionnaire (Pittsburgh Sleep Quality Index or PSQI), Epworth Sleepiness Scale (ESS) and Stop Bang questionnaire (STOP BANG)...
November 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29297523/znwo4-nanocrystals-synthesis-morphology-photoluminescence-and-photocatalytic-properties
#12
P F S Pereira, A F Gouveia, M Assis, R C de Oliveira, I M Pinatti, M Penha, R F Gonçalves, L Gracia, J Andrés, E Longo
The present joint experimental and theoretical work provides in-depth understanding on the morphology and structural, electronic, and optical properties of ZnWO4 nanocrystals. Monoclinic ZnWO4 nanocrystals were prepared at three different temperatures (140, 150, and 160 °C) by a microwave hydrothermal method. Then, the samples were investigated by X-ray diffraction with Rietveld refinement analysis, field-emission scanning electron microscopy, transmission electronic microscopy, micro-Raman and Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, and photoluminescence measurements...
January 3, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29289963/treatment-guidelines-for-circadian-rhythm-sleep-wake-disorders-of-the-polish-sleep-research-society-and-the-section-of-biological-psychiatry-of-the-polish-psychiatric-association-part-ii-diagnosis-and-treatment
#13
REVIEW
Adam Wichniak, Konrad S Jankowski, Michał Skalski, Krystyna Skwarło-Sońta, Jolanta B Zawilska, Marcin Żarowski, Ewa Poradowska, Wojciech Jernajczyk
AIM: Circadian rhythm sleep-wake disorders (CRSWD) are a group of disorders, in which the timing of sleep and wakefulness significantly differs from a patient's expectations or socially acceptable times. The aimof the article is to present the current principles for the diagnosis and treatment of CRSWD in adults and children. METHOD: Guidelines proposed as CRSWD treatment standard are based on the recommendations from the scientific societies involved in the sleep research and medicine...
October 29, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29282790/an-evaluation-of-a-specialist-firesetting-treatment-programme-for-male-and-female-mentally-disordered-offenders-the-fip-mo
#14
Nichola Tyler, Theresa A Gannon, Lona Lockerbie, Caoilte Ó Ciardha
Individuals who set deliberate fires are frequently encountered by clinicians working in forensic mental health services. However, little attention has been paid to developing standardised treatment for this behaviour, and few evaluations of treatment have been conducted in forensic mental health services. This study evaluates a new standardised group cognitive behavioural treatment programme for individuals residing in forensic psychiatric hospitals who have engaged in deliberate firesetting (The Firesetting Intervention Programme for Mentally Disordered Offenders; FIP-MO)...
December 28, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29280745/sex-assignment-in-conditions-affecting-sex-development
#15
Renata Markosyan, S Faisal Ahmed
The newborn infant with atypical genitalia presents a challenging clinical scenario and requires expert input. There have been appreciable advances in our knowledge of the underlying causes that may lead to a mere difference or a more serious disorder of sex development (DSD), the natural history of conditions, as well as the short and long-term complications of these conditions themselves, together with the clinical interventions that are associated with these conditions. With this information, the DSD expert can be more confident when discussing options with the parents of the newborn infant...
December 27, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29277137/effects-of-stress-on-critical-care-nurses-a-national-cross-sectional-study
#16
Amir Vahedian-Azimi, Mohammadreza Hajiesmaeili, Mari Kangasniemi, Joana Fornés-Vives, Rita L Hunsucker, Farshid Rahimibashar, Mohammad A Pourhoseingholi, Leily Farrokhvar, Andrew C Miller
BACKGROUND: Health care is a demanding field, with a high level of responsibility and exposure to emotional and physical danger. High levels of stress may result in depression, anxiety, burnout syndrome, and in extreme cases, post-traumatic stress disorder. The aim of this study was to determine which personal, professional, and organizational variables are associated with greater perceived stress among critical care nurses for purposes of developing integrative solutions to decrease stress in the future...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29249375/towards-remote-monitoring-of-parkinson-s-disease-tremor-using-wearable-motion-capture-systems
#17
Mehdi Delrobaei, Sara Memar, Marcus Pieterman, Tyler W Stratton, Kenneth McIsaac, Mandar Jog
The management of movement disorders is shifting from a centralized-clinical assessment towards remote monitoring and individualized therapy. While a variety of treatment options are available, ranging from pharmaceutical drugs to invasive neuromodulation, the clinical effects are inconsistent and often poorly measured. For instance, the lack of remote monitoring has been a major limitation to optimize therapeutic interventions for patients with Parkinson's Disease (PD). In this work, we focus on the assessment of full-body tremor as the most recognized PD symptom...
January 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29243580/coumarins-as-promising-scaffold-for-the-treatment-of-age-related-diseases-an-overview-of-the-last-five-years
#18
Giovanna Lucia Delogu, Maria Joao Matos
Degenerative diseases are becoming increasingly prevalent with the aging of the human population. The twentieth century witnessed a significant demographic change in the industrialized world that is currently followed by a similar shift of life expectancy to upper age ranges in Asia, Africa, and Middle and South America. A rising tide of chronic age-dependent diseases will soon present serious challenges for these countries. Age-related diseases are commonly seen in older patients. More than 40% of adults 60 and older have a combination of risk factors known as metabolic syndrome, which increases the risk for developing degenerative disorders, and certain cancers...
December 14, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/29229227/the-importance-of-the-circadian-system-sleep-for-bone-health
#19
Christine M Swanson, Wendy M Kohrt, Orfeu M Buxton, Carol A Everson, Kenneth P Wright, Eric S Orwoll, Steven A Shea
Adequate sleep timed appropriately during the circadian night is important for numerous biological processes and systems. New evidence suggests that both sleep timing and duration may be important for optimal bone health as well. This review examines the diurnal variation of bone turnover markers (BTMs) and the importance of circadian clock genes in regulating bone mass. In addition, this review explores the evidence for a link between shift work (and its associated disturbances in sleep duration/quality and circadian alignment) and alterations in bone metabolism and bone health...
December 8, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29224581/executive-function-and-other-cognitive-deficits-are-distal-risk-factors-of-generalized-anxiety-disorder-9-years-later
#20
Nur Hani Zainal, Michelle G Newman
OBJECTIVE: The cognitive model (Hirsch & Mathews, 2012) and attentional control theory (Eysenck & Derakshan, 2011) postulate that compromised executive function (EF) and other cognitive constructs are negatively linked to increased excessive and uncontrollable worry, the core symptom of generalized anxiety disorder (GAD). However, the prospective link between neuropsychological constructs and GAD are not well understood. METHODS: A nationally representative sample of 2605 community-dwelling adults whose average age was 55...
December 11, 2017: Psychological Medicine
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