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Shift work disorder

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https://www.readbyqxmd.com/read/29782073/a-focus-group-study-exploring-student-nurse-s-experiences-of-an-educational-intervention-focuse-don-working-with-people-with-a-diagnosis-of-personality-disorder
#1
G Stacey, V Baldwin, B Thompson, A Aubeeluck
INTRODUCTION: Negative attitudes exist in practice towards those with a diagnosis of personality disorder. Preregistration training offers the opportunity to address this by developing understanding of the diagnosis, confidence in working with people with the diagnosis and empowering new nurses to challenge prevailing attitudes. Attempts to integrate and evaluate specific educational interventions of this nature into pre-registration nurse education have not been explored elsewhere. AIM: To explore preregistration nurses' experience of a programme of training focused on personality disorder and their perception of its influence on attitudes, understanding of clients and their experience of practice...
May 21, 2018: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29766042/bc-rna-mislocalization-in-the-fragile-x-premutation
#2
Ilham A Muslimov, Taesun Eom, Anna Iacoangeli, Shih-Chieh Chuang, Renate K Hukema, Rob Willemsen, Dimitre G Stefanov, Robert K S Wong, Henri Tiedge
Fragile X premutation disorder is caused by CGG triplet repeat expansions in the 5' untranslated region of FMR1 mRNA. The question of how expanded CGG repeats cause disease is a subject of continuing debate. Our work indicates that CGG-repeat structures compete with regulatory BC1 RNA for access to RNA transport factor hnRNP A2. As a result, BC1 RNA is mislocalized in vivo, as its synapto-dendritic presence is severely diminished in brains of CGG-repeat knock-in animals (a premutation mouse model). Lack of BC1 RNA is known to cause seizure activity and cognitive dysfunction...
March 2018: ENeuro
https://www.readbyqxmd.com/read/29758574/-relationship-between-the-use-of-psychosomatic-rehabilitation-and-regional-capacities-for-medical-and-psychotherapeutic-treatment-of-mental-disorders-in-westphalia
#3
Elena Köckerling, Jürgen Breckenkamp, Bettina Hesse
BACKGROUND: Regional disparities in mental health care are well known and become apparent in inadequate treatment capacities and long waiting time for psychotherapeutic treatment. Hence, the authors assume that there is a shift from curative to rehabilitative care. Accordingly, the purpose of this study was to analyze the relationship between regional treatment capacities and the use of psychosomatic rehabilitation on behalf of the German Statutory Pension Insurance Westphalia (i. e...
May 14, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29743782/effect-of-shift-work-on-sleep-health-and-quality-of-life-of-health-care-workers
#4
Evangelia Nena, Maria Katsaouni, Paschalis Steiropoulos, Evangelos Theodorou, Theodoros C Constantinidis, Grigorios Tripsianis
Background: Shift work is associated with sleep disruption, impaired quality of life, and is a risk factor for several health conditions. Aim of this study was to investigate the impact of shift work on sleep and quality of life of health-care workers (HCW). Settings: Tertiary University hospital in Greece. Study Design: Cross-sectional study. Materials and Methods: Included were HCW, working either in an irregular shift system or exclusively in morning shifts...
January 2018: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29743318/shift-work-night-work-and-sleep-disorders-among-pastry-cookers-and-shopkeepers-in-france-a-cross-sectional-survey
#5
Emilie Pepin, Pascal Gillet, Fabien Sauvet, Danielle Gomez-Merino, Isabelle Thaon, Mounir Chennaoui, Damien Leger
OBJECTIVE: Most research on night and shift work focuses on employee health in large companies, primarily in the healthcare and transportation sectors. However, many night workers work on their own or in small businesses related to services or food. This survey focuses on sleep habits and disorders concerning night work in pastry production and sales. METHODS: An epidemiological telephone cross-sectional survey of night shift workers and their sleep habits was proposed to all employers and employees in the French pastry industry via their insurance health prevention company...
May 9, 2018: BMJ Open
https://www.readbyqxmd.com/read/29737354/tunable-dielectric-transitions-in-layered-organic-inorganic-hybrid-perovskite-type-compounds-nh-3-ch-2-2-cl-2-cdcl-4-4x-br-4x-x-0-1-4-1
#6
Hai-Peng Chen, Ping-Ping Shi, Zhong-Xia Wang, Ji-Xing Gao, Wan-Ying Zhang, Cheng Chen, Yuan-Yuan Tang, Da-Wei Fu
Molecular bistable dielectric switches represent a class of highly desirable intelligent materials due to their sensitive switchable responses, simple and environmentally friendly processing, light weights, and mechanical flexibility. However, most of these switches can only work at a very low temperature, extremely limiting their potential applications. Herein, three layered organic-inorganic hybrid perovskite-type compounds of the general formula A2BX4, [NH3(CH2)2Cl]2[CdCl3Br] (1), [NH3(CH2)2Cl]2[CdCl4] (2) and [NH3(CH2)2Cl]2[CdBr4] (3), which display sensitive dielectric switching reversibility and remarkable switching anti-fatigue, have been successfully designed...
May 8, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29737315/applicability-of-transoral-endoscopic-parathyroidectomy-through-vestibular-route-for-primary-sporadic-hyperparathyroidism-a-south-indian-experience
#7
P R K Bhargav, M Sabaretnam, V Amar, N Vimala Devi
Introduction: Primary hyperparathyroidism is one of the most common endocrine disorders requiring surgical parathyroidectomy for its definitive treatment. Surgical exploration is traditionally performed through conventional open neck approach. A wide range of minimal access and minimally invasive endoscopic techniques (gas less and with gas) have been attempted in the past two decades. In this context, we evaluated the feasibility and safety of an innovative transoral endoscopic parathyroidectomy (EP) technique, which represents a paradigm shift in transluminal endocrine surgery...
May 4, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29735750/systematic-review-of-fit-note-use-for-workers-in-the-uk
#8
Sarah Dorrington, Emmert Roberts, Arnstein Mykletun, Stephani Hatch, Ira Madan, Matthew Hotopf
OBJECTIVES: The fit note, introduced in England, Wales and Scotland in 2010, was designed to change radically the sickness certification process from advising individuals on their inability to work to advising them on what they could do if work could be adapted. Our review aimed to evaluate the following: (1) Is the 'maybe fit' for work option being selected for patients? (2) Are work solutions being recommended? (3) Has the fit note increased return to work? (4) Has the fit note reduced the length of sickness absence? We considered the way in which outcomes vary according to patient demographics including type of health problem...
May 7, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29721646/meta-analysis-of-the-effects-of-computerized-cognitive-training-on-executive-functions-a-cross-disciplinary-taxonomy-for-classifying-outcome-cognitive-factors
#9
REVIEW
Shannon L Webb, Vanessa Loh, Amit Lampit, Joel E Bateman, Damian P Birney
The growing prevalence of neurodegenerative disorders associated with aging and cognitive decline has generated increasing cross-disciplinary interest in non-pharmacological interventions, such as computerized cognitive training (CCT), which may prevent or slow cognitive decline. However, inconsistent findings across meta-analytic reviews in the field suggest a lack of cross-disciplinary consensus and on-going debate regarding the benefits of CCT. We posit that a contributing factor is the lack of a theoretically-based taxonomy of constructs and representative tasks typically used...
May 3, 2018: Neuropsychology Review
https://www.readbyqxmd.com/read/29719201/conformational-ensemble-and-biological-role-of-the-tctp-intrinsically-disordered-region-influence-of-calcium-and-phosphorylation
#10
Florian Malard, Nadine Assrir, Mouad Alami, Samir Messaoudi, Ewen Lescop, Tâp Ha-Duong
The translationally controlled tumor protein (TCTP) is a multifunctional protein that may interact with many other bio-mole-cules, including itself. The experimental determinations of TCTP structure revealed a folded core domain and an intrinsically disordered region, which includes the first highly conserved TCTP signature, but whose role in the protein functions remains to be elucidated. In this work, we combined NMR experiments and MD simulations to characterize the conformational ensemble of the TCTP intrinsically disordered loop, in the presence or not of calcium ions and with or without the phosphorylation of Ser46 and Ser64...
April 29, 2018: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29707422/modafinil-for-the-improvement-of-patient-outcomes-following-traumatic-brain-injury
#11
REVIEW
Amne Borghol, Michael Aucoin, Ifeanyichukwu Onor, Dana Jamero, Fadi Hawawini
Objective : The authors sought to assess the literature evidence on the efficacy of modafinil use in patients with fatigue or excessive daytime sleepiness (EDS) secondary to traumatic brain injury (TBI). Method of Research : A literature search of Medline and PubMed was performed using the EBSCOhost database. Primary literature, observational studies, meta-analyses, case reports, and systematic reviews were assessed for content regarding modafinil and psychostimulant use in patients with TBI. Of the 23 articles collected, three randomized, controlled studies, three observational studies, one case report, and two systematic reviews gave a description of modafinil use in TBI patients...
April 1, 2018: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/29706157/what-happens-to-disinhibited-social-engagement-disorder-over-time
#12
EDITORIAL
Helen Minnis
Disinhibited social engagement disorder (DSED) is one of the most intriguing syndromes in child and adolescent psychiatry but also one of the least understood. We know little about its developmental course in different groups of children, so I was delighted to see the incisive longitudinal work from the Bucharest Early Intervention Study by Guyon-Harris and colleagues.1 My own interest in DSED was sparked back in the early 1990s, when a travel bug had taken me to Guatemala and I had found a job in an orphanage...
May 2018: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29701630/assessing-and-managing-the-shift-work-disorder-in-healthcare-workers
#13
Gabriele D'Ettorre, Vincenza Pellicani, Mariarita Greco, Mauro Mazzotta, Annamaria Vullo
BACKGROUND: Shift work disorder (SWD) is a major concern for both healthcare workers (HCWs) employed in hospital wards and healthcare organizations. The consequences of SWD may lead to increased service costs and lower standards of care. OBJECTIVES: To identify and evaluate the latest developments in assessing and managing the occupational risk of SWD in shift-HCWs through a search of the literature published in the last five years. METHODS: We performed a search of the literature starting from June 2012, using MEDLINE/Pubmed...
February 20, 2018: La Medicina del Lavoro
https://www.readbyqxmd.com/read/29680433/night-shift-work-increases-cold-pain-perception
#14
Christoph Pieh, Robert Jank, Christoph Waiß, Christian Pfeifer, Thomas Probst, Claas Lahmann, Stefan Oberndorfer
BACKGROUND: Although night-shift work (NSW) is associated with a higher risk for several physical and mental disorders, the impact of NSW on pain perception is still unclear. This study investigates the impact of NSW on cold pain perception considering the impact of mood and sleepiness. METHOD: Quantitative sensory testing (QST) was performed in healthy night-shift workers. Cold pain threshold as well as tonic cold pain was assessed after one habitual night (T1), after a 12-hour NSW (T2) and after one recovery night (T3)...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29680177/individual-vulnerability-to-insomnia-excessive-sleepiness-and-shift-work-disorder-amongst-healthcare-shift-workers-a-systematic-review
#15
REVIEW
Lauren A Booker, Michelle Magee, Shantha M W Rajaratnam, Tracey L Sletten, Mark E Howard
Shift workers often experience reduced sleep quality, duration and/or excessive sleepiness due to the imposed conflict between work and their circadian system. About 20-30% of shift workers experience prominent insomnia symptoms and excessive daytime sleepiness consistent with the circadian rhythm sleep disorder known as shift work disorder. Individual factors may influence this vulnerability to shift work disorder or sleep-related impairment associated with shift work. This paper was registered with Prospero and was conducted using recommended standards for systematic reviews and meta-analyses...
March 27, 2018: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29669140/night-work-and-hypertensive-disorders-of-pregnancy-a-national-register-based-cohort-study
#16
Paula Hammer, Esben Flachs, Ina Specht, Anja Pinborg, Sesilje Petersen, Ann Larsen, Karin Hougaard, Johnni Hansen, Åse Hansen, Henrik Kolstad, Anne Garde, Jens Peter Bonde
Objective The aim of this study was to investigate whether night work expressed by number and duration of night shifts, number of consecutive night shifts, and number of quick returns during the first 20 weeks of pregnancy is a risk factor for hypertensive disorders of pregnancy (HDP). Methods The study population comprised Danish workers in public administration and hospitals who gave birth between 2007 and 2013. Exposure was assessed objectively through payroll data. Information on the outcome was retrieved from the National Patient Register...
April 18, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29666146/identification-of-circadian-clock-modulators-from-existing-drugs
#17
T Katherine Tamai, Yusuke Nakane, Wataru Ota, Akane Kobayashi, Masateru Ishiguro, Naoya Kadofusa, Keisuke Ikegami, Kazuhiro Yagita, Yasufumi Shigeyoshi, Masaki Sudo, Taeko Nishiwaki-Ohkawa, Ayato Sato, Takashi Yoshimura
Chronic circadian disruption due to shift work or frequent travel across time zones leads to jet-lag and an increased risk of diabetes, cardiovascular disease, and cancer. The development of new pharmaceuticals to treat circadian disorders, however, is costly and hugely time-consuming. We therefore performed a high-throughput chemical screen of existing drugs for circadian clock modulators in human U2OS cells, with the aim of repurposing known bioactive compounds. Approximately 5% of the drugs screened altered circadian period, including the period-shortening compound dehydroepiandrosterone (DHEA; also known as prasterone)...
April 17, 2018: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/29627704/bipolar-disorder-and-obsessive-compulsive-disorder-the-comorbidity-does-not-further-impair-the-neurocognitive-profile
#18
Renato de Filippis, Matteo Aloi, Antonella Bruni, Raffaele Gaetano, Cristina Segura-Garcia, Pasquale De Fazio
BACKGROUND: The comorbidity of bipolar disorder (BD) and obsessive-compulsive disorder (OCD) has been widely described. Several studies have investigated the cognitive profiles of BD and OCD patients, but studies that compare BD, BD-OCD, and OCD patients in neuropsychological domains do not exist. The purpose of this study was to compare set-shifting, decision making, and central coherence among BD, BD-OCD, and OCD patients. METHODS: A battery of neuropsychological tests was administered to 68 patients (22 BD, 26 BD-OCD, 20 OCD)...
March 29, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29627464/letter-to-the-editor
#19
Reza Khodarahmi
I read with great interest the paper by Dehvari and Ghahghaei (Dehvari and Ghahghaei, 2018 [1]). Their paper aimed to prove that biosynthesized AgNPs mediated by Pulicaria undulata L. has the capability in inhibiting amyloid fibril formation and thus could be considered as a therapeutic agent in the treatment of amyloidosis disorders. According to the literature (Jangholi et al., 2018 [2]), Thioflavin T (ThT) is a commonly used probe to monitor in vitro amyloid fibril formation. Also, since ThT fluorescence originates only from the bound population of the dye molecules, the several orders of magnitude increase in the fluorescence intensity makes ThT an unusually sensitive and efficient reporter...
April 5, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29618913/evaluation-of-work-related-musculoskeletal-disorders-and-postural-stress-of-female-jari-workers
#20
Amitava Pal, Prakash C Dhara
Aims: The present investigation was aimed to assess the postural stress and the prevalence of musculoskeletal disorders (MSDs) of the "Jari" (golden thread) workers. Settings and Design: This cross-sectional study was carried out on 156 female workers in different areas of the Purba Medinipur, Paschim Medinipur, and Howrah districts of West Bengal, India. Materials and Methods: The MSDs of the workers were evaluated by modified Nordic questionnaire method...
September 2017: Indian Journal of Occupational and Environmental Medicine
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