keyword
https://read.qxmd.com/read/38523877/effect-of-dexmedetomidine-on-oxygen-and-intrapulmonary-shunt-qs-qt-during-one-lung-ventilation-in-pediatric-surgery-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Ayham Khddam, Faten Rostom, Mohammad Y Hajeer
Background One-lung ventilation (OLV) is a common ventilation technique used during thoracic surgery. It can cause serious complications in children, and hypoxic pulmonary vasoconstriction (HPV) is a protective mechanism against the resulting hypoxia. Dexmedetomidine does not affect HPV, so we will investigate its impact on the partial pressure of oxygen in arterial blood (PaO2) and pulmonary shunt fraction (Qs/Qt). Methods Children who underwent OLV were divided into two equal groups. The Dex group received 0...
March 2024: Curēus
https://read.qxmd.com/read/38519434/clinical-correlates-of-respiratory-disorders-in-patients-with-severe-multiple-sclerosis-a-cross-sectional-cohort
#2
JOURNAL ARTICLE
Elisabeth Maillart, Stefania Redolfi, Céline Louapre, Marion Houot, Emeline Chaugne, Pierantonio Laveneziana, Aurelian Ungureanu, Bruno Stankoff, Isabelle Arnulf, Caroline Papeix, Benedetta Bodini, Thomas Similowski, Catherine Lubetzki, Capucine Morélot-Panzini
BACKGROUND: Respiratory disorders remain incompletely described in multiple sclerosis (MS), even though they are a frequent cause of death. METHODS: The objective was to describe respiratory disorders in MS patients with Expanded Disability Status Score (EDSS) ⩾ 6.5. Diaphragm dysfunction was defined by at least two of the seven criteria: clinical signs, inspiratory recruitment of neck muscles during wakefulness, reduced upright vital capacity (VC) < 80%, upright-to-supine VC ⩾ 15% of upright VC, decrease in Maximal Inspiratory Pressure < 60%, phasic activation of inspiratory neck muscles during sleep, and opposition of thoracic and abdominal movements during sleep...
March 22, 2024: Multiple Sclerosis: Clinical and Laboratory Research
https://read.qxmd.com/read/38512578/comparison-of-deep-and-moderate-neuromuscular-blockade-for-major-laparoscopic-surgery-in-children-a-randomized-controlled-trial
#3
JOURNAL ARTICLE
Guo Wei, Yong-Xin Li, Ying Chen, Mei Diao, John Wei Zhong, Shou-Dong Pan
BACKGROUND AND OBJECTIVE: Neuromuscular blocking agents are routinely used in laparoscopic surgery to optimize operative conditions. We compared the effect of a deep and moderate neuromuscular blockade (NMB) on surgical conditions and postoperative outcomes in children undergoing major laparoscopic surgery. METHODS: Sixty children aged 2-14 years scheduled to undergo major laparoscopic surgery were randomly allocated to deep (post-tetanic count 1-2 twitches) or moderate (train-of-four 1-2 twitches) NMB groups...
March 21, 2024: Paediatric Drugs
https://read.qxmd.com/read/38507025/comparison-of-the-effects-of-paratracheal-pressure-and-cricoid-pressure-on-placement-of-the-i-gel-%C3%A2-supraglottic-airway-a-randomized-clinical-trial
#4
JOURNAL ARTICLE
Dongwook Won, Hyerim Kim, Jee-Eun Chang, Jung-Man Lee, Tae Kyong Kim, Honghyeon Kim, Seong-Won Min, Jin-Young Hwang
PURPOSE: Anesthesiologists can use supraglottic airway devices as a rescue technique for failed intubation even in patients with an increased risk of gastric regurgitation. In this randomized study, we aimed to evaluate the effects of cricoid pressure and paratracheal pressure on placement of the i-gel® (Intersurgical Ltd., Wokingham, Berkshire, UK). METHODS: After induction of anesthesia in 76 adult patients, we inserted the i-gel under paratracheal or cricoid pressure, and assessed the success rate of i-gel insertion, resistance during insertion, time required for insertion, accuracy of the insertion location, tidal volumes, and peak inspiratory pressure with or without each maneuver after i-gel insertion...
March 20, 2024: Canadian Journal of Anaesthesia
https://read.qxmd.com/read/38502558/therapeutic-approach-to-dysphagia-in-post-covid-patients-in-a-rehabilitation-unit-a-descriptive-longitudinal-study
#5
JOURNAL ARTICLE
Anna Guillen-Sola, Cindry Ramírez, Sonia Nieto, Esther Duarte, Marta Tejero, Christian Grillo, Helena Bel, Roser Boza
BACKGROUND: A high rate of hospitalized patients for COVID-19 had dysphagia, frequently underdiagnosed, and not treated, inducing a prolonged dysphagia with protracted recovery. Specific treatments and protocols have not been well described yet. AIM: Given the potential benefits of respiratory muscle training (IEMT) and neuromuscular stimulation (NMES) in dysphagia treatment, this study aimed to assess the feasibility of the protocol used for treating dysphagia in patients who experienced prolonged hospitalization for COVID-19...
March 19, 2024: European Journal of Physical and Rehabilitation Medicine
https://read.qxmd.com/read/38491861/the-effect-of-laser-resistant-endotracheal-tube-design-on-airflow-dynamics-a-benchtop-and-clinical-study
#6
JOURNAL ARTICLE
Jessica M L Pagel, Adithya Reddy, Lucy Fitzgerald, Mohamed Tiouririne, Patrick O McGarey, Daniel B Quinn, James J Daniero
OBJECTIVE: Compare ventilation pressures of 2 endotracheal tube designs used in laser airway surgery in clinical practice and with a benchtop model to elucidate differences and understand the design elements that impact airflow dynamics. METHODS: Ventilatory and aerodynamic characteristics of the laser resistant stainless-steel endotracheal tube (LRSS-ET) design and the laser resistant aluminum-wrapped silicone endotracheal tube (LRAS-ET) design were compared. Ventilatory parameters were collected for 32 patients undergoing laser-assisted airway surgery through retrospective chart review...
March 16, 2024: Annals of Otology, Rhinology, and Laryngology
https://read.qxmd.com/read/38489949/do-proprioceptive-neuromuscular-facilitation-techniques-improve-respiratory-parameters-and-swallowing-in-people-with-multiple-sclerosis-a-randomized-controlled-study
#7
JOURNAL ARTICLE
Julide Kesebir, Rabia Gokcen Gozubatık Celik, Yonca Zenginler, Burcu Yüksel, Aysu Sen, Buket Akinci
AIM: This study aims to investigate the effects of Proprioceptive Neuromuscular Facilitation (PNF) techniques on respiratory parameters, swallowing, functional capacity, fatigue, and quality of life in people with Multiple Sclerosis (PwMS). METHOD: Thirty-four PwMS were included and randomized into the PNF Group (mean age: 43.23±10.55/years) or Control Group (mean age:38.47±8.18/years). In the PNF group, head-neck, upper extremity, trunk, and breathing techniques were applied three days/eight weeks...
March 11, 2024: Multiple Sclerosis and related Disorders
https://read.qxmd.com/read/38476539/comparison-of-nasal-and-face-mask-ventilation-in-anaesthetised-obese-adults-a-randomised-controlled-study
#8
JOURNAL ARTICLE
Gyan Singh, Neeru Luthra, Richa Jain, Anju Grewal, Shubham Garg, Livleen Deep Mann
BACKGROUND AND AIMS: The use of a face mask while inducing general anaesthesia (GA) in obese patients is often ineffective in providing adequate ventilation. Although nasal mask ventilation has demonstrated effectiveness for continuous positive airway pressure (CPAP) in obese patients with obstructive sleep apnoea (OSA), it has not yet been applied to the induction of anaesthesia. This study evaluated the efficacy of nasal mask ventilation against standard face mask ventilation in anaesthetised obese patients with body mass index (BMI)>25 kg/m2 ...
March 2024: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38460974/pilot-observational-cohort-study-to-determine-whether-waveform-and-flow-traces-from-mechanical-insufflation-exsufflation-mi-e-can-be-used-to-identify-laryngeal-responses-to-mi-e-and-thus-optimise-treatment-algorithms-in-neuromuscular-patients-in-a-tertiary
#9
JOURNAL ARTICLE
Stephanie K Mansell, Rhiannon Parry, Amar Shah, Francesca Gowing, Charlotte Greenfield, Yogesh Bhatt, Swapna Mandal
INTRODUCTION: Patients with neuromuscular disease often have a weak and ineffective cough due to respiratory muscle weakness. One treatment option is mechanical insufflation-exsufflation (MI-E), also known as cough assist, which is known to increase cough strength. However, some patients have a laryngeal response to MI-E, which can make the treatment ineffective. Currently, the only method for assessing this is via nasal endoscopy while using MI-E. Some MI-E devices have onboard secure data (SD) cards, which allow the visualisation of waveforms...
March 9, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38448933/differences-of-respiratory-mechanics-in-mechanical-ventilation-of-acute-respiratory-distress-syndrome-between-patients-with-covid-19-and-influenza-a
#10
JOURNAL ARTICLE
Eunki Chung, Ah Young Leem, Kyung Soo Chung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Hye Jin Jang, Su Hwan Lee
BACKGROUND: Whether COVID-19-induced acute respiratory distress syndrome (ARDS) should be approached differently in terms of mechanical ventilation therapy compared to other virus-induced ARDS is debatable. Therefore, we aimed to ascertain whether the respiratory mechanical characteristics of COVID-19-induced ARDS differ from those of influenza A induced ARDS, in order to establish a rationale for mechanical ventilation therapy in COVID-19-induced ARDS. METHODS: This was a retrospective cohort study comparing patients with COVID-19-induced ARDS and influenza A induced ARDS...
March 7, 2024: Respiratory Research
https://read.qxmd.com/read/38442928/-clinical-study-of-optimal-positive-end-expiratory-pressure-titration-guided-by-lung-stretch-index-in-patients-with-acute-respiratory-distress-syndrome
#11
RANDOMIZED CONTROLLED TRIAL
Kai Hu, Caixia Yin, Xuan Xiong, Yu Xie, Bujun Li, Lixin Zhou
OBJECTIVE: To investigate the clinical practicability of positive end-expiratory pressure (PEEP) titrated by lung stretch index (SI) in patients with acute respiratory distress syndrome (ARDS). METHODS: A parallel randomized controlled trial was conducted. Patients with moderate to severe ARDS who required mechanical ventilation admitted to the department of critical care medicine of General Hospital of the Yangtze River Shipping from August 2022 to February 2023 were enrolled...
February 2024: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/38436754/a-nasal-airflow-oscillation-device-targeting-nasal-congestion-a-preliminary-report
#12
JOURNAL ARTICLE
Jim Bartley, Robin Hankin
PURPOSE: Upper respiratory tract complaints are common in the general population. A safe, non-pharmacologic treatment would be an attractive option for many patients either as an alternative to existing therapies, or as a complementary therapy. This study assessed the acceptability, safety and possible efficacy of a nasal airflow oscillation device in a group of people suffering chronic nasal congestion. METHODS: Subjects with a known history of nasal congestion, but without fixed anatomical obstruction, participated in a prospective clinical study...
March 4, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38413871/intraoperative-mechanical-power-and-postoperative-pulmonary-complications-in-low-risk-surgical-patients-a-prospective-observational-cohort-study
#13
JOURNAL ARTICLE
Mohamad El-Khatib, Carine Zeeni, Fadia M Shebbo, Cynthia Karam, Bilal Safi, Aline Toukhtarian, Nancy Abou Nafeh, Samar Mkhayel, Carol Abi Shadid, Sana Chalhoub, Jean Beresian
BACKGROUND: Inadequate intraoperative mechanical ventilation (MV) can lead to ventilator-induced lung injury and increased risk for postoperative pulmonary complications (PPCs). Mechanical power (MP) was shown to be a valuable indicator for MV outcomes in critical care patients. The aim of this study is to assess the association between intraoperative MP in low-risk surgical patients undergoing general anesthesia and PPCs. METHODS: Two-hundred eighteen low-risk surgical patients undergoing general anesthesia for elective surgery were included in the study...
February 27, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38383309/the-effects-of-respiratory-muscle-training-on-respiratory-function-and-functional-capacity-in-patients-with-early-stroke-a-meta-analysis
#14
REVIEW
Yun-Shan Zhang, Kai Zhang, Lang Huang, Jing-Xue Wei, Zi-Ting Bi, Jing-Hua Xiao, Jian Huang, Chao-Song Luo, Ying-Dong Li, Jia-Mei Zhang
BACKGROUND: Respiratory muscle training is a continuous and standardized training of respiratory muscles, but the evidence of the effects on early stroke patients is not clear. This meta-analysis aimed to investigate the effects of respiratory muscle training on respiratory function and functional capacity in patients with early stroke. METHODS: PubMed, Embase, PEDro, ScienceDirect, AMED, CINAHL, and China National Knowledge Infrastructure databases were searched from inception to December 8, 2023 for articles about studies that 1) stroke patients with age ≥ 18 years old...
February 22, 2024: European Review of Aging and Physical Activity
https://read.qxmd.com/read/38337582/supplementary-respiratory-therapy-improves-pulmonary-function-in-pediatric-patients-with-cerebral-palsy-a-systematic-review-and-meta-analysis
#15
REVIEW
Erika Kolumbán, Márton Szabados, Márk Hernádfői, Uyen Nguyen Do To, Rita Nagy, Ádám Zolcsák, Katalin Eszter Müller, Zoltán Sipos, Dániel Sándor Veres, Anett Szőllősi, Péter Hegyi, Miklós Garami, Ibolya Túri
BACKGROUND: Despite medical advances, individuals with cerebral palsy (CP) face significant respiratory challenges, leading to heightened hospitalization rates and early mortality among this population. We hypothesize that integrating supplementary respiratory therapy into standard rehabilitation will result in significant improvements in pulmonary function, enhanced respiratory muscle strength, and an overall increase in the quality of life among pediatric patients with CP. METHODS: A systematic search of literature across five databases was conducted, and random-effects meta-analyses were performed to assess the impact of supplementary respiratory therapy on (a) pulmonary function: forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FVC/FEV1 ratio, peak expiratory flow (PEF), and (b) respiratory muscle strength: maximal inspiratory and expiratory pressure (MIP, MEP), and (c) quality of life...
February 2, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38336616/effects-of-pressure-controlled-ventilation-targeting-end-inspiratory-flow-rate-on-pulmonary-complications-and-inflammation-levels-in-patients-undergoing-spinal-surgery-in-the-prone-position-a-randomized-clinical-trial
#16
RANDOMIZED CONTROLLED TRIAL
Na Wang, Yong Ye, Hui Lin, Tingting Sun, Yue Hu, Yuanhang Shu, Jing Tong, Yong Tao, Zeyu Zhao
BACKGROUND: This study assessed the impact of pressure-controlled ventilation (PCV) focusing on end-inspiratory flow rate on the incidence of postoperative pulmonary complications (PPCs) and inflammation levels in patients undergoing spinal surgery in the prone position. METHODS: A total of 187 patients who underwent posterior spinal surgery were enrolled and randomly divided into 3 groups: 61 in the volume-controlled ventilation (VCV) group (group V), 62 in the PCV-volume-guaranteed (VG) group (group P1 ), and 64 in the PCV-VG end-expiratory zero flow rate group (group P2 )...
February 9, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38329601/respiratory-function-and-respiratory-muscle-strength-in-adolescent-idiopathic-scoliosis
#17
JOURNAL ARTICLE
İrem Çetinkaya, Tuğba Kuru Çolak, Seda Saka, Mehmet Fatih Korkmaz
PURPOSE: It was aimed to analyze the relationship of the respiratory functions, respiratory muscle strength, magnitude of the curvature, angle of trunk rotation (ATR) and brace-wearing duration in patients with adolescent idiopathic scoliosis (AIS). METHODS: Sixty patients with AIS (43 females), with maximum Cobb angles between 20° and 66° were included in the study. ATR values were measured with a scoliometer. Respiratory function parameters (forced vital capacity [FVC], forced expiratory volume in one second [FEV1], FEV1/FVC ratio, peak expiratory flow [PEF]) and respiratory muscle strengths (maximum inspiratory pressure [MIP] and maximum expiratory pressure [MEP]) were measured by combined spirometry...
February 8, 2024: Spine Deformity
https://read.qxmd.com/read/38318664/recapitulation-of-human-pathophysiology-and-identification-of-forensic-biomarkers-in-a-translational-model-of-chlorine-inhalation-injury
#18
JOURNAL ARTICLE
Satyanarayana Achanta, Michael A Gentile, Carolyn J Albert, Kevin A Schulte, Brooke G Pantazides, Brian S Crow, Jennifer Quinones-Gonzalez, Jonas W Perez, David A Ford, Rakesh P Patel, Thomas A Blake, Michael D Gunn, Sven E Jordt
Chlorine gas (Cl2 ) has been repeatedly used as a chemical weapon, first in World War I and most recently in Syria. Life-threatening Cl2 exposures frequently occur in domestic and occupational environments, and in transportation accidents. Modeling the human etiology of Cl2 -induced acute lung injury (ALI), forensic biomarkers, and targeted countermeasures development have been hampered by inadequate large animal models. The objective of this study was to develop a translational model of Cl2 -induced ALI in swine to understand toxico-pathophysiology and is suitable for screening potential medical countermeasures, and identify biomarkers useful for forensic analysis...
February 6, 2024: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://read.qxmd.com/read/38318454/case-report-neurally-adjusted-ventilatory-assist-as-an-effective-rescue-treatment-for-pulmonary-interstitial-emphysema-in-extremely-low-birth-weight-infants
#19
Chien-Ming Chen, Mei-Yung Chung, Hong-Ya Kang, Mei-Chen Ou-Yang, Teh-Ming Wang, Chung-Ting Hsu
Pulmonary interstitial emphysema (PIE) is a complication observed in extremely low birth weight (ELBW) infants on mechanical ventilation. Despite various proposed therapeutic interventions, the success rates have shown inconsistency. Neurally adjusted ventilatory assist (NAVA) stands out as a novel respiratory support mode, offering lower pressure and tidal volume in comparison to conventional ventilation methods. In this case report, we present five ELBW infants with refractory PIE who were transitioned to NAVA ventilation...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38315040/efficacy-of-respiratory-muscle-training-in-the-immediate-postoperative-period-of-cardiac-surgery-a-systematic-review-and-meta-analysis
#20
REVIEW
Tarcísio Nema de Aquino, João Paulo Prado, Ernesto Crisafulli, Enrico Maria Clini, Giovane Galdino
INTRODUCTION: This study aimed to evaluate the efficacy of respiratory muscle training during the immediate postoperative period of cardiac surgery on respiratory muscle strength, pulmonary function, functional capacity, and length of hospital stay. METHODS: This is a systematic review and meta-analysis. A comprehensive search on PubMed®, Excerpta Medica Database (or Embase), Cumulative Index of Nursing and Allied Health Literature (or CINAHL), Latin American and Caribbean Health Sciences Literature (or LILACS), Scientific Electronic Library Online (or SciELO), Physiotherapy Evidence Database (or PEDro), and Cochrane Central Register of Controlled Trials databases was performed...
February 5, 2024: Brazilian Journal of Cardiovascular Surgery
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