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https://www.readbyqxmd.com/read/27855994/flexural-resistance-of-heat-pressed-and-cad-cam-lithium-disilicate-with-different-translucencies
#1
Riccardo Fabian Fonzar, Michele Carrabba, Maurizio Sedda, Marco Ferrari, Cecilia Goracci, Alessandro Vichi
OBJECTIVE: To compare flexural strength of CAD-CAM and heat-pressed lithium disilicate. METHODS: For Pressed specimens (Group A), acrylate polymer blocks were cut with a saw in bars shape. Sprueing, investing and preheating procedures were carried out following manufacturer's instructions. IPS e.max Press ingots (Ivoclar-Vivadent) were divided into subgroups (n=15) according to translucency: A.1=HT-A3; A.2=MT-A3; A.3=LT-A3; A.4=MO2. Ingots were then pressed following manufacturer's instructions...
November 14, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/27822952/sprue-like-enteropathy-associated-with-olmesartan-in-a-patient-with-villous-atrophy-hla-dq2-genotype-and-antinuclear-antibodies
#2
Isidro Machado, María Reolid, Fernando Martínez de Juan, Carmen Martínez Lapiedra, Fernanda Maia de Alcántara
We describe a new case of enteropathy with villous atrophy in a patient suffering from arterial hypertension treated with olmesartan. The molecular and serological studies showed anti-nuclear antibodies (ANA) and haplotype HLA-DQ2 positive, as well as negative results for anti-transglutaminase, anti-endomysium and anti-enterocytes antibodies. A duodenal villous atrophy was suspected by upper gastrointestinal endoscopy, which was confirmed by histopathology. The morphological picture was suggestive of sprue-like enteropathy with severe lymphoid infiltration and predominant T lymphoid cells...
November 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27808143/sprue-like-enteropathy-associated-with-oxcarbazepine
#3
Pedro Luis González-Cordero, Nuria Fernandez-Gonzalez, Javier Molina-Infante
No abstract text is available yet for this article.
November 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27803820/seronegative-intestinal-villous-atrophy-a-diagnostic-challenge
#4
Cláudio Martins, Cristina Teixeira, Suzane Ribeiro, Daniel Trabulo, Cláudia Cardoso, João Mangualde, Ricardo Freire, Ana Luísa Alves, Élia Gamito, Isabelle Cremers, Ana Paula Oliveira
Celiac disease is the most important cause of intestinal villous atrophy. Seronegative intestinal villous atrophy, including those that are nonresponsive to a gluten-free diet, is a diagnostic challenge. In these cases, before establishing the diagnosis of seronegative celiac disease, alternative etiologies of atrophic enteropathy should be considered. Recently, a new clinical entity responsible for seronegative villous atrophy was described-olmesartan-induced sprue-like enteropathy. Herein, we report two uncommon cases of atrophic enteropathy in patients with arterial hypertension under olmesartan, who presented with severe chronic diarrhea and significant involuntary weight loss...
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27784420/a-night-of-no-sleep
#5
Bhanu Prakash Kolla, Meghna P Mansukhani, Steven I Altchuler
Ms. C, a 20-year-old female was referred for a sleep evaluation for hypersomnia. She reported increasing sleepiness over a period of one year. She described a pattern of retiring to bed at 2000 hours with an initial sleep latency of 10 minutes. She would sleep uninterrupted until 0630 hours and wake to an alarm clock. She avoided napping during the day. Her history was otherwise not suggestive of narcolepsy or sleep apnea. She was not on any medications and had a medical history significant only for celiac sprue...
October 20, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27753658/immunohistochemical-expression-of-antitissue-transglutaminase-2-in-tissue-injuries-an-interpretation-beyond-celiac-disease
#6
Prasenjit Das, Ramakant Rawat, Anil K Verma, Geetika Singh, Archana G Vallonthaiel, Rajni Yadav, Gaurav P S Gahlot, Amit K Dinda, Vineet Ahuja, Siddhartha Datta Gupta, Sanjay K Agarwal, Govind K Makharia
Tissue transglutaminase 2 enzyme plays a diverse role in intracellular and extracellular functioning. Aberrant expression of anti-TG2 antibody has recently been proposed for extraintestinal identification of celiac disease (CeD), but its utility is questionable. To examine whether anti-TG2 immunohistochemical (IHC) staining can be of diagnostic value in identifying extraintestinal involvement in CeD, tissue blocks of patients with IgA nephropathies (IgAN), minimal change disease, membranous glomerulonephritis, membrano-proliferative glomerulonephritis, normal kidney, intestinal biopsies from CeD, tropical sprue, nonspecific duodenitis, and inflammatory bowel disease; liver biopsies from patients with chronic hepatitis B and C, acute liver failure (ALF), and CeD-associated liver diseases were retrieved and subjected to IHC staining for anti-tissue transglutaminase 2 enzyme...
October 7, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27636919/-malabsorption-is-a-leading-clinical-sign-of-small-bowel-disease
#7
A I Parfenov, L M Krums
The paper presents a variety of clinical manifestations of malabsorption syndrome (MAS) in celiac disease, collagenous sprue, Whipple's disease, Crohn's disease, intestinal lymphangiectasia, amyloidosis, common variable immune deficiency, and treatment of short bowel syndrome. It shows the specific features of the pathophysiology, diagnosis, and treatment of MAS in small bowel diseases.
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27621502/ranolazine-induced-reversible-t-wave-inversions-with-prolonged-qtc-interval-progressive-multifocal-leukoencephalopathy-linked-to-fingolimod-losartan-induced-sprue-like-enteropathy-nivolumab-induced-psoriasiform-skin-eruption-hepatitis-b-reactivation-with-hepatitis
#8
EDITORIAL
Michael A Mancano
The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MED WATCH program (800-FDA-1088). If you have reported an interesting, preventable ADR to MED WATCH, please consider sharing the account with our readers. Write to Dr. Mancano at ISMP, 200 Lakeside Drive, Suite 200, Horsham, PA 19044 (phone: 215-707-4936; e-mail: mmancano@temple.edu). Your report will be published anonymously unless otherwise requested...
November 2015: Hospital Pharmacy
https://www.readbyqxmd.com/read/27620860/comparison-of-clinical-features-treatment-and-outcomes-of-collagenous-sprue-celiac-disease-and-collagenous-colitis
#9
Nan Lan, Bo Shen, Lisi Yuan, Xiuli Liu
BACKGROUND: Collagenous sprue (CS) is a rare form of enteropathy that had been reported to be associated with celiac disease (CD) and collagenous colitis (CC). The aim of our study was to compare the clinical features, treatments and outcomes of CS, CD, and CC. METHODS: All patients with histologic diagnosis of CS, CD or CC with complete clinical data were extracted from our pathology database between 1990 and 2015. Demographic and clinical features were recorded along with treatments and outcomes...
September 13, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27486523/the-first-cases-of-collagenous-sprue-successfully-treated-with-thioguanine
#10
Tom van Gils, Tine van de Donk, Gerd Bouma, Foke van Delft, E Andra Neefjes-Borst, Chris J J Mulder
OBJECTIVE: Collagenous sprue (CS) is a rare form of small bowel enteropathy characterised by a thickened basement membrane and is, in most of the literature, reported as part of coeliac disease. Multiple treatment strategies are suggested in CS, but there is no standardised therapy. The aim of this series is to describe 4 cases of CS and to propose thioguanine (6-TG) treatment. DESIGN: We reviewed 4 cases of CS. Data were obtained from our prospective database of patients referred to our coeliac centre...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27486350/elderly-onset-celiac-disease-a-narrative-review
#11
REVIEW
Maria Cappello, Gaetano C Morreale, Anna Licata
Celiac sprue is a chronic disease, which usually occurs in children and young adults. However, it can develop in any age group, and the prevalence is increasing even in the elderly population. The atypical patterns of clinical presentation in this age group sometimes can cause a delay in diagnosis. Given the lower sensitivity and specificity of serological tests in the aged population, clinical suspect often arises in the presence of complications (autoimmune disorders, fractures, and finally, malignancy) and must be supported by endoscopic and imaging tools...
2016: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/27446852/duodenal-villous-atrophy-in-a-ttg-negative-patient-taking-olmesartan-a-case-report-and-review-of-the-literature
#12
Tasha Kulai, Thomas Arnason, Donald MacIntosh, John Igoe
Olmesartan, an angiotensin II receptor antagonist used to treat hypertension, is associated with few adverse effects. Here, a case of severe sprue-like enteropathy and acute kidney injury is described in a 68-year-old male taking olmesartan for 3-4 years. He presented to hospital with a five-week history of diarrhea, vomiting, and a 20 lb weight loss. Anti-TTG was negative with a normal IgA. Biopsies of the distal duodenum and duodenal cap revealed marked blunting of the villi with near complete villous atrophy of the biopsies from the bulb...
2016: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27446843/adding-water-to-the-mill-olmesartan-induced-collagenous-sprue-a-case-report-and-brief-literature-review
#13
Claudine Desruisseaux, Michaël Bensoussan, Etienne Désilets, Hanh-Khiem Tran, Robert Arcand, Germain Poirier, Andrew Wisniewski, Thibaut Manière
Collagenous sprue (CS) is a distinct clinicopathological disorder histologically defined by a thickened subepithelial band (Freeman, 2011). It is a rare condition which has been recently observed in a significant proportion of sprue-like enteropathy associated with olmesartan, a novel entity described by Rubio-Tapia et al. in 2012. CS is historically associated with a poor prognosis (Marthey et al., 2014). However, histological and clinical improvements have been described in most studies with concomitant usage of corticosteroids and/or gluten-free diet (Marthey et al...
2016: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27280200/olmesartan-sprue-like-enteropathy
#14
(no author information available yet)
A cohort study conducted in 2014, using data from France's mandatory health insurance system, has shown a 10-fold increased risk of hospitalisation for enteropathy with olmesartan in comparison with other ARBs (sartans) or ACE inhibitors. The increased incidence of enteropathy with olmesartan compared with other ARBs or ACE inhibitors is well documented. The French drug regulatory agency, ANSM, informed healthcare professionals of these risks in 2014. Yet prescription rates for olmesartan remain high, and new cases of olmesartan-associated enteropathy continue to be reported...
May 2016: Prescrire International
https://www.readbyqxmd.com/read/27195041/the-maladies-of-malabsorption
#15
Rashmi Patnayak, Vaikkakara Suresh, Amitabh Jena, Kadiyala Madhu, Bobbit Venkatesh Phaneendra, Venkatrami Reddy
Malabsorption syndrome (MAS) is a common condition in India. In Indian adults, tropical sprue and celiac disease are leading causes of MAS. Sometimes, the diagnosis of MAS may pose a challenge due to the varied signs and symptoms. We present a case of MAS in a young female, whose presenting symptoms were mainly neurological. She was successfully treated under regular follow-up for the past 6 years without any symptoms.
January 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/27109007/clinical-laboratory-serological-and-histological-profile-of-sprue-like-enteropathy-associated-with-olmesartan-use
#16
Esteban Sáez González, Francia Carolina Díaz Jaime, Adolfo Del Val Antoñana
Olmesartan is one of the various angiotensin II antagonists currently used for the management of high blood pressure. A sprue-like enteropathy was first described in 2012 in association with this antihypertensive drug. An observational, descriptive study was carried out on a series of 12 patients who met the clinical, histopathological, and outcome criteria for olmesartan-related sprue-like enteropathy from May 2013 to December 2015. All patients had watery diarrhea, weight loss, and negative celiac serology...
April 25, 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27099732/olmesartan-induced-enteropathy-associated-with-cutaneous-lesions
#17
Nassim Hammoudi, Marie Dior, Vincent Giraud, Benoit Coffin
Olmesartan is an angiotensin II receptor antagonist which may cause severe sprue-like enteropathy with duodenal villous atrophy. Skin lesions may be associated as reported for the first time in our case. Clinicians should be informed of this side effect and its reversibility after suspension of the drug.
April 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27053352/association-between-common-variable-immunodeficiency-and-collagenous-infiltrative-disorders-of-the-gastrointestinal-tract-a-series-of-four-patients
#18
Rohan Mandaliya, Ashlie L Burkart, Anthony J DiMarino, Satish Rattan, Sidney Cohen
Hypogammaglobulinemia/common variable immunodeficiency (CVID) may lead to disruption of the gut mucosal immune barrier. Collagenous infiltrative disorders of the intestinal tract (colitis, gastritis, sprue) constitute a relatively new spectrum of gastrointestinal disorders. Our aims were (1) to determine the association between immunoglobulin deficiency state like CVID and collagenous infiltrative disorders of the gut and (2) to study the clinic-pathologic characteristics and treatment outcomes in these patients...
March 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27001009/olmesartan-associated-sprue-like-enteropathy-know-your-enemy
#19
Gianluca Ianiro, Antonio Gasbarrini, Giovanni Cammarota
No abstract text is available yet for this article.
July 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/26997446/olmesartan-associated-sprue-like-enteropathy-a-systematic-review-with-emphasis-on-histopathology
#20
REVIEW
Nina Burbure, Benjamin Lebwohl, Carolina Arguelles-Grande, Peter H R Green, Govind Bhagat, Stephen Lagana
Sprue-like enteropathy associated with the angiotensin II receptor blocker (ARB) olmesartan was first described in 2012, and a number of cases have since been reported. This syndrome is characterized by severe diarrhea and sprue-like histopathologic findings in the intestine, often with increased subepithelial collagen. The incidence of this adverse drug reaction is not entirely clear, although it is thought to be rare. It is also not well established if other ARBs cause such a syndrome, although case reports suggest they can...
April 2016: Human Pathology
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