keyword
MENU ▼
Read by QxMD icon Read
search

Stroke treatment

keyword
https://www.readbyqxmd.com/read/29909569/economic-burden-of-stroke-a-systematic-review-on-post-stroke-care
#1
S Rajsic, H Gothe, H H Borba, G Sroczynski, J Vujicic, T Toell, Uwe Siebert
OBJECTIVES: Stroke is a leading cause for disability and morbidity associated with increased economic burden due to treatment and post-stroke care (PSC). The aim of our study is to provide information on resource consumption for PSC, to identify relevant cost drivers, and to discuss potential information gaps. METHODS: A systematic literature review on economic studies reporting PSC-associated data was performed in PubMed/MEDLINE, Scopus/Elsevier and Cochrane databases, Google Scholar and gray literature ranging from January 2000 to August 2016...
June 16, 2018: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29909378/delayed-ischemic-stroke-due-to-stent-marker-band-occlusion-after-stent-assisted-coiling
#2
Shuhei Kawabata, Hirotoshi Imamura, Keita Suzuki, Shoichi Tani, Hidemitsu Adachi, Nobuyuki Sakai
A middle-aged patient with an internal carotid-posterior communicating artery aneurysm and basilar artery tip aneurysm was treated by stent-assisted coiling. One ischemic infarction and two transient ischemic attacks occurred with the same symptoms (inability to walk unassisted and tendency to fall to the left) during the first 2 years post-treatment. The ischemic infarction was found in the right side of the pons, consistent with the vascular territory of the stent-containing vessel. The cause of the delayed ischemic stroke was investigated on DSA and cone beam CT, which revealed that the proximal end of the stent, one marker band, was just covering a small perforating artery of the basilar artery trunk...
June 16, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29909184/rates-causes-risk-factors-and-outcomes-of-readmission-following-deep-brain-stimulation-for-movement-disorders-analysis-of-the-u-s-nationwide-readmissions-database
#3
Kavelin Rumalla, Kyle A Smith, Kenneth A Follett, Jules M Nazzaro, Paul M Arnold
OBJECTIVE: Deep brain stimulation (DBS) surgery has proven benefit for several movement disorders and medically-refractory psychiatric conditions and is considered a fairly safe procedure. We sought to determine the national rates, causes, predictors, and outcomes associated with 30-day and 90-day readmission. PATIENTS AND METHODS: The Nationwide Readmissions Database was queried (January-September 2013) using ICD-9-CM codes, identifying patients who underwent DBS for movement disorder (Parkinson's disease [PD], essential tremor [ET], or dystonia)...
June 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29909038/engineered-stem-cell-mimics-to-enhance-stroke-recovery
#4
Paul M George, Byeongtaek Oh, Ruby Dewi, Thuy Hua, Lei Cai, Alexa Levinson, Xibin Liang, Brad A Krajina, Tonya M Bliss, Sarah C Heilshorn, Gary K Steinberg
Currently, no medical therapies exist to augment stroke recovery. Stem cells are an intriguing treatment option being evaluated, but cell-based therapies have several challenges including developing a stable cell product with long term reproducibility. Since much of the improvement observed from cellular therapeutics is believed to result from trophic factors the stem cells release over time, biomaterials are well-positioned to deliver these important molecules in a similar fashion. Here we show that essential trophic factors secreted from stem cells can be effectively released from a multi-component hydrogel system into the post-stroke environment...
June 13, 2018: Biomaterials
https://www.readbyqxmd.com/read/29908420/ticagrelor-versus-clopidogrel-after-fibrinolytic-therapy-in-patients-with-st-elevation-myocardial-infarction-rationale-and-design-of-the-ticagrelor-in-patients-with-st-elevation-myocardial-infarction-treated-with-thrombolysis-treat-trial
#5
Otavio Berwanger, Jose C Nicolau, Antonio C Carvalho, Lixin Jiang, Shaun Goodman, Stephen J Nicholls, Alexander Parkhomenko, Oleg Averkov, Carlos Tajer, Germán Malaga, Jose F Kerr Saraiva, Francisco Fonseca, Helio P Guimaraes, Pedro G M de Barros E Silva, Lucas P Damiani, Denise M Paisani, Camila M R Lasagno, Carolina T Candido, Nanci Valeis, Diogo D F Moia, Leopoldo S Piegas, Christopher B Granger, Harvey White, Renato D Lopes
BACKGROUND: The safety and efficacy of ticagrelor in patients with ST-elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remain uncertain. OBJECTIVES: The primary objective of the TicagRElor in pAtients with ST elevation myocardial infarction treated with Thrombolysis (TREAT) trial is to evaluate the short-term safety of ticagrelor when compared with clopidogrel in STEMI patients treated with fibrinolytic therapy. Key secondary objectives are to assess the safety and efficacy of ticagrelor compared with clopidogrel at 12-months...
March 3, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29908347/aging-related-functional-and-structural-changes-in-the-heart-and-aorta-mitotempo-improves-aged-cardiovascular-performance
#6
Yusuf Olgar, Sinan Degirmenci, Aysegul Durak, Deniz Billur, Belgin Can, Gizem Kayki Mutlu, Ebru Arioglu Inan, Belma Turan
Aging in humans represents declining in cardio-protective systems, however its mechanisms are not known yet. We aimed to analyse how aging affects key mechanisms responsible for contractile dysfunction via comparing the improperly synchrony between electrical and mechanical activities in male aged-rats (24-month old) comparison to those of adult-rats (6-month old). We determined significantly increased systemic oxidative stress with decreased antioxidant capacity, clear insulin resistance and hypertrophy in aged-rats with normal fasting blood glucose...
June 13, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29907947/introduction-of-direct-oral-anticoagulant-within-7-days-of-stroke-onset-a-nomogram-to-predict-the-probability-of-3-month-modified-rankin-scale-score-2
#7
Manuel Cappellari, Gianni Turcato, Stefano Forlivesi, Nicola Micheletti, Giampaolo Tomelleri, Bruno Bonetti, Giovanni Merlino, Roberto Eleopra, Monia Russo, Roberto L'Erario, Alessandro Adami, Carolina Gentile, Anna Gaudenzi, Sandro Bruno, Paolo Bovi
In clinical practice, direct oral anticoagulants (DOACs) are often started earlier (≤ 7 days) than in randomized clinical trials after stroke. We aimed to develop a nomogram model incorporating time of DOAC introduction ≤ 7 days of stroke onset in combination with different degrees of stroke radiological/neurological severity at the time of treatment to predict the probability of unfavorable outcome. We conducted a multicenter prospective study including 344 patients who started DOAC 1-7 days after atrial fibrillation-related stroke onset...
June 15, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29907575/current-evidence-for-anesthesia-management-during-endovascular-stroke-therapy-updated-systematic-review-and-meta-analysis
#8
Nitin Goyal, Konark Malhotra, Muhammad F Ishfaq, Georgios Tsivgoulis, Christopher Nickele, Daniel Hoit, Adam S Arthur, Andrei V Alexandrov, Lucas Elijovich
INTRODUCTION: Debate continues about the optimal anesthetic management for patients undergoing endovascular treatment (ET) of acute ischemic stroke due to emergent large vessel occlusion. OBJECTIVE: To compare, using current evidence, the clinical outcomes and procedural characteristics among patients undergoing general anesthesia (GA) and local or monitored anesthesia (non-GA). METHODS: We performed a systematic review and meta-analysis of all available studies that involved the use of stent retrievers for ET (stentriever group)...
June 15, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29907089/temporarily-increased-stroke-rate-after-takotsubo-syndrome-need-for-an-anticoagulation
#9
Nadine Abanador-Kamper, Lars Kamper, Judith Wolfertz, Marc Vorpahl, Patrick Haage, Melchior Seyfarth
BACKGROUND: Previous studies have reported slightly higher stroke rates in Takotsubo Syndrome compared to acute myocardial infarction. Our goal was to evaluate the temporal course of stroke rates and left ventricular recovery in patients with Takotsubo Syndrome. METHODS: We retrospectively examined the clinical and imaging data of 72 patients with Takotsubo Syndrome. The data collected came from January 2005 to March 2017. Left ventricular performance was evaluated by cardiovascular magnetic resonance imaging (MRI) in all patients during the acute phase of Takotsubo Syndrome and in a follow-up scan 2 months later...
June 15, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29906425/diastolic-hypotension-may-attenuate-benefits-from-intensive-systolic-targets-secondary-analysis-of-a-randomized-controlled-trial
#10
Todd C Lee, Rodrigo B Cavalcanti, Emily G McDonald, Louise Pilote, James M Brophy
BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) was a randomized controlled trial which studied 9361 adults aged 50 and older with systolic blood pressure above 130mmHg and one or more cardiovascular risk factor. Patients were randomized to intensive (≤ 120mmHg) or standard (≤ 140mmHg) systolic targets. In August 2016, a limited dataset was released for secondary analysis. We hypothesized that excessive lowering of diastolic blood pressure could cause harm. Using the data from SPRINT, we sought to determine whether the development of diastolic hypotension during treatment was associated with adverse outcomes...
June 12, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29904963/experience-of-a-single-center-in-the-conservative-approach-of-20-consecutive-cases-of-asymptomatic-extracranial-carotid-artery-aneurysms
#11
V E C Pourier, J C Welleweerd, L J Kappelle, G J E Rinkel, Y M Ruigrok, H B van der Worp, T H Lo, M L Bots, F L Moll, Gert J de Borst
BACKGROUND: The clinical course and optimal treatment strategy for asymptomatic aneurysms of the extracranial carotid artery (ECAA) are unknown. We report our single-center experience with conservative management of patients with an asymptomatic ECAA. METHODS: A search in our hospital records from 1998 to 2013 revealed 20 patients (mean age 52 years, SD 12.5) with 23 ECAA, defined as a 150% or more fusiform dilation or any saccular dilatation compared to the healthy internal carotid artery...
June 14, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29904828/estrogen-migraine-and-vascular-risk
#12
Gianni Allais, Giulia Chiarle, Silvia Sinigaglia, Gisella Airola, Paola Schiapparelli, Chiara Benedetto
Migraine has a predilection for female sex and the course of symptoms is influenced by life stage (presence of menstrual cycle, pregnancy, puerperium, menopause) and use of hormone therapy, such as hormonal contraception and hormone replacement therapy. Hormonal changes figure among common migraine triggers, especially sudden estrogen drop. Moreover, estrogens can modulate neuronal excitability, through serotonin, norepinephrine, dopamine, and endorphin regulation, and they interact with the vascular endothelium of the brain...
June 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29904091/naloxone-attenuates-ischemic-brain-injury-in-rats-through-suppressing-the-nik-ikk%C3%AE-nf-%C3%AE%C2%BAb-and-neuronal-apoptotic-pathways
#13
Xuan Wang, Zu-Jun Sun, Jun-Lu Wu, Wen-Qiang Quan, Wei-Dong Xiao, Helen Chew, Cui-Min Jiang, Dong Li
Although naloxone has been documented to exert neuroprotection in animal model of cerebral ischemia, the mechanism is not well understood. In this present study we investigated whether naloxone affected the mitochondrial apoptotic pathway in ischemic brain injury of rats. SD rats were subjected to a permanent middle cerebral artery occlusion surgery, and received naloxone (0.5, 1, 2 mg/kg, i.v.) immediately after ischemia. Neurological deficits were evaluated 24 h after ischemia using the McGraw Stroke Index, and then the rats were killed, and the brains were collected for further analyses...
June 14, 2018: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/29904043/effect-of-neuro-orthopaedic-surgery-for-spastic-equinovarus-foot-after-stroke-a-prospective-longitudinal-study-based-on-a-goal-centered-approach
#14
Thierry Deltombe, Maxime Gilliaux, François Peret, Mie Leeuwerck, Delphine Wautier, Philippe Hanson, Thierry Gustin
BACKGROUND: Neuro-orthopaedic surgery is recognized as an effective treatment to improve walking capacity in case of spastic equinovarus foot. However, the effect of surgery on the 3 domains of the International Classification of Functioning, Disability and Health (ICF) has never been studied. AIM: To assess the efficacy of the neuro-orthopaedic surgery for spastic equinovarus foot after stroke based on a goal-centered approach and on the 3 domains of the International Classification of Functioning, Disability and Health (ICF)...
June 14, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29903845/adiponectin-free-fatty-acids-and-cardiovascular-outcomes-in-patients-with-type-2-diabetes-and-acute-coronary-syndrome
#15
Ilse C Schrieks, Anna Nozza, Barbara E Stähli, John B Buse, Robert R Henry, Klas Malmberg, Bruce Neal, Stephen J Nicholls, Lars Rydén, Linda Mellbin, Anders Svensson, Hans Wedel, Arlette Weichert, A Michael Lincoff, Jean-Claude Tardif, Diederick E Grobbee, Gregory G Schwartz
OBJECTIVE: In observational cohorts, adiponectin is inversely associated and free fatty acids (FFAs) are directly associated with incident coronary heart disease (CHD). Adiponectin tends to be reduced and FFAs elevated in type 2 diabetes. We investigated relationships of adiponectin and FFA and major adverse cardiovascular events (MACEs) and death in patients with acute coronary syndrome (ACS) and type 2 diabetes using data from the AleCardio trial, which compared the PPAR-α/γ agonist aleglitazar with placebo...
June 14, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29903520/a-meta-analysis-of-randomized-controlled-trials-of-uninterrupted-periprocedural-anticoagulation-strategy-in-patients-undergoing-atrial-fibrillation-catheter-ablation
#16
Yating Zhao, Yao Lu, Yue Qin
BACKGROUND: In patients undergoing atrial fibrillation (AF) ablation, despite uninterrupted oral anticoagulants (OACs) have been recommended, no consensus has emerged regarding to whether uninterrupted novel oral anticoagulants (NOACs) are superior to uninterrupted vitamin K antagonists (VKAs) for the periprocedural antithrombotic management. This meta-analysis aimed to compare the efficacy and safety of uninterrupted NOACs and uninterrupted VKAs in patients undergoing AF ablation. METHODS: Databases were searched for articles published up to March 20, 2018...
June 8, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29903519/transcatheter-or-surgical-treatment-of-severe-aortic-stenosis-and-coronary-artery-disease-a-comparative-analysis-from-the-italian-observant-study
#17
Marco Barbanti, Sergio Buccheri, Davide Capodanno, Paola D'Errigo, Marco Ranucci, Stefano Rosato, Gennaro Santoro, Danilo Fusco, Corrado Tamburino, Fausto Biancari, Fulvia Seccareccia
BACKGROUND: To assess clinical outcomes of patients with concomitant severe aortic stenosis (AS) and coronary artery disease (CAD) who underwent transcatheter aortic valve implantation (TAVI) and percutaneous coronary intervention (PCI) or surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG). METHODS: Data were extracted from the multicenter OBSERVANT study. For the purposes of the present analysis, we included only patients with established stable CAD meeting any of the following inclusion criteria: 1) TAVI patients with CAD undergoing staged PCI or TAVI and PCI in the same session; 2) SAVR patients undergoing combined SAVR and CABG in the same session...
June 7, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29903515/the-nonalcoholic-fatty-liver-disease-nafld-fibrosis-score-cardiovascular-risk-stratification-and-a-strategy-for-secondary-prevention-with-ezetimibe
#18
Tracey G Simon, Kathleen E Corey, Christopher P Cannon, Michael Blazing, Jeong-Gun Park, Michelle L O'Donoghue, Raymond T Chung, Robert P Giugliano
OBJECTIVE: The nonalcoholic fatty liver disease fibrosis score (NFS) is comprised of unique metabolic risk indicators that may accurately predict residual cardiovascular (CV) risk in patients with established coronary disease and metabolic dysfunction. METHODS: We applied the NFS prospectively to 14,819 post-ACS patients randomized to ezetimibe/simvastatin (E/S) or placebo/simvastatin (P/S), in the IMPROVE-IT trial, using validated NFS cutoffs. The primary endpoint included CV death, myocardial infarction, unstable angina, revascularization or stroke...
May 26, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29903395/incidence-prognosis-and-prediction-of-haemorrhagic-transformation-after-revascularisation-for-stroke
#19
P B García Jurado, E Roldán Romero, M E Pérez Montilla, R Valverde Moyano, I M Bravo Rey, F Delgado Acosta, F A Bravo-Rodríguez
INTRODUCTION: Haemorrhagic transformation is a major complication of acute ischaemic stroke (AIS). We sought to determine the predictors and clinical impact of intracranial haemorrhage (ICH) after revascularisation therapy. METHODS: We conducted a retrospective, single-centre study including 235 patients with AIS who underwent intravenous recombinant tissue plasminogen activator (IV-rtPA) therapy and/or endovascular treatment. A binary logistic regression model was used to determine the variables associated with ICH, parenchymal haematomas (PH), modified Rankin Scale (mRS) scores, and mortality...
June 11, 2018: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/29901642/treatment-of-poststroke-constipation-with-moxibustion-a-case-report
#20
Junmao Wen, Zhenjie Zhuang, Minhong Zhao, Dongming Xie, Bo Xie, Lixing Zhuang, Zheng Liang, Wei Wu, Hongwei Xu
RATIONALE: Moxibustion, an important therapeutic measure of TCM, can stimulate acupoints to unblock the meridians and collaterals, regulate the function of qi and blood, support health, and expel pathogens. So it could be an effective and safe for the treatment of constipation and improvement of the quality of life in poststroke patients with constipation. PATIENT CONCERNS: He has a history of constipation, with the defecation of hard, bound stool every 2 to 3 days with the help of glycerin enema...
June 2018: Medicine (Baltimore)
keyword
keyword
25524
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"