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Saghar Safamanesh, Amir Azimian, Abdolreza Shakeri, Kiarash Ghazvini, Saeid Amel Jamehdar, Mahsa Khosrojerdi, Masoud Youssefi
Porcine bocavirus (PBoV) is a recently discovered virus classified within the Bocavirus genus. We present a case of upper respiratory tract infection associated with PBoV in a three-year-old child who was in close contact with hogs in northeastern Iran. To the best of our knowledge, this is the first report on the human PBoV infection. Upcoming reports from different regions of the world could provide a generalized view of the spread of pig-to-human transmission of the virus.
March 15, 2018: Pediatric Infectious Disease Journal
Amir Wolff, Gabriel F Santiago, Micah Belzberg, Omri Emodi, Chad R Gordon
INTRODUCTION: Combined mid-face and nasal apparatus trauma injuries pose a significant challenge to airway patency (AW), in the immediate postoperative setting following fracture reduction. As such, the authors describe a modified technique with the goal of maintaining a patent nasal AW, while at the same time, minimizing nasopharyngeal bleeding and nasal AW edema-which can complicate patients requiring intermaxillary fixation (IMF) in the setting of pan-facial trauma. METHODS: A modified technique was devised to assist the reconstruction surgeon in avoiding the risks associated with tracheostomy placement...
March 20, 2018: Journal of Craniofacial Surgery
Amir Hanna, Adrian Crutu, Pierre Baldeyrou
No abstract text is available yet for this article.
April 2018: Journal of Bronchology & Interventional Pulmonology
Afsane Bahrami, Hamidreza Bahrami-Taghanaki, Mozhgan Afkhamizadeh, Amir Avan, Zahra Mazloum Khorasani, Habibollah Esmaeili, Bahareh Amin, Samine Jazebi, Delaram Kamali, Gordon A Ferns, Hamid Reza Sadeghnia, Majid Ghayour-Mobarhan
There have been several studies evaluating the association between vitamin and mineral status and menstrual disturbance. In the present study, we aimed to assess the relationship between the menstrual bleeding pattern and premenstrual syndrome (PMS) symptoms with serum 25-hydroxyvitamin D, and calcium levels in adolescent girls. A cross-sectional study was carried out in 897 high school girls from northeastern Iran. The prevalence of hypocalcaemia, normal serum calcium and hypercalcaemia was 27.1, 59.8 and 13...
March 21, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Georgios Klironomos, Amir R Dehdashti
No abstract text is available yet for this article.
March 20, 2018: Acta Neurochirurgica
Ahmad Piroozmand, Babak Soltani, Mohsen Razavizadeh, Amir Hasan Matini, Hamid Reza Gilasi, Abbas Nassaji Zavareh, Siamak Soltani
Background and aim: Helicobacter pylori ( H. pylori ) is an important and common contagious human pathogen which may cause peptic ulcer and also gastric cancer. The definite diagnosis of it is made through invasive tests. Recently, non-invasive tests including serologic tests of serum and saliva have been conducted for diagnosis of H. pylori infection. In this research, the diagnostic values of serum and salivary serology were compared together to use salivary anti- H. pylori test as an alternative method in the future...
December 2017: Electronic Physician
Ahmad Piroozmand, Babak Soltani, Mohsen Razavizadeh, Amir Hasan Matini, Gholam Abbas Moosavi, Mohammad Salehi, Siamak Soltani
Background and aim: Triggering receptor expressed on myeloid cells (TREM-1) is a receptor on phagocytes that is triggered by infectious agents. The soluble form of it (sTREM-1) can be elevated in gastric juice by Helicobacter pylori ( H. pylori ) infection of gastric mucosa. The aim of this study was to compare the diagnostic values of sTREM-1 and C-reactive protein (CRP) for detection of H. pylori infection in gastric mucosa. Methods: In this diagnostic accuracy study on cases who underwent endoscopy from March 2015 to July 2016 in Shahid Beheshti Hospital, Kashan, Iran, gastric juice sTREM-1 and CRP concentrations were measured by enzyme-linked immunosorbent assays (ELISA) and their diagnostic values were compared to detect H...
December 2017: Electronic Physician
Amir Emami Zeydi, Hossein Karimi Moonaghi, Abbas Heydari
Background: Despite the clinical importance of adherence to treatment in β-Thalassemia Major (β-TM) patients, poor adherence remains a prevalent and persistent problem in these patients. Objective: The aim of this study was to explore Iranian β-TM patients' perception regarding the barriers and facilitators of adherence to their treatments. Methods: In this qualitative study, data were collected using purposeful sampling and semi-structured interviews with 18 β-TM patients, 3 family members and 5 healthcare professionals (total=26) in Sari, northern Iran, between August 2015 and May 2017...
December 2017: Electronic Physician
Amir Kiakojori, Seyede Parisa Motamedi Nasab, Farida Abesi, Hemmat Gholinia
Background and aim: Given the importance of evaluating the maxillary sinus lateral wall thickness (LWT) to avoid complications during surgery, the aim of this study was to examine LWT as well as the effect of residual ridge height (RH), edentulous region, type of edentulism, age and gender on it. Methods: In this cross-sectional study conducted in 2016, 150 samples of the CBCT imaging archives of the Oral and Maxillofacial Radiology Clinic in Babol, Iran, were evaluated retrospectively...
December 2017: Electronic Physician
Alireza Vakilian, Seyed Moein Razavi-Nasab, Ali Ravari, Tayebeh Mirzaei, Amir Moghadam-Ahmadi, Nazanin Jalali, Reza Bahramabadi, Mohammadtaghi Rezayati, Amin Yazdanpanah-Ravari, Farhad Bahmaniar, Mohammad Reza Bagheri, Mahmood Sheikh Fathollahi, Gholamreza Asadikaram, Mohammad Kazemi Arababadi
INTRODUCTION: Patients with Alzheimer disease (AD) suffer from psychotic symptoms including pain. The current antipsychotic drugs confer limited effectiveness, and hence new strategies are being designed to decrease pain in order to increase antipsychological effectiveness. Vitamin B12 is a safe supplementary drug to decrease pain. Additionally, cytokines participate in the pathogenesis of immune-related diseases such as AD. Thus, the main aim of this clinical trial study was to determine the effects of treatment with risperidone and quetiapine, as antipsychotic drugs, with and without vitamin B12 on the psychotic symptoms of AD patients and the expression of IL-6, IL-8, tumor growth factor (TGF)-β, tumor necrosis factor (TNF)-α, and endothelin (ET)-1)...
March 20, 2018: Neuroimmunomodulation
Beena Negi, Prija Poonan, Mohammad Fawad Ansari, Deepak Kumar, Sakshi Aggarwal, Ramandeep Singh, Amir Azam, Diwan S Rawat
A series of 22 novel metronidazole-triazole-styryl hybrids were synthesized and evaluated for their in vitro antiamoebic activity against HM1: IMSS strain of Entamoeba histolytica. Some of the hybrids were found to be more active (IC50  = 0.12-0.35 μM) than the reference drug metronidazole (IC50  = 1.79 μM). The most active compounds were found to be non-toxic (up to 50 μM) against the Vero cells showing a good safety profile of these hybrids. The docking and ADMET studies were also conducted to investigate the probable mode of action...
March 13, 2018: European Journal of Medicinal Chemistry
Akhilesh Kumar, Manas Ranjan Dikhit, Ajay Amit, Amir Zaidi, Raj Kishor Pandey, Ashish Kumar Singh, Shashi S Suman, Vahab Ali, Vidya Nand Rabi Das, Krishna Pandey, Vikas Kumar, Shubhankar Kumar Singh, Shyam Narayan, Hirendra Kumar Chourasia, Pradeep Das, Sanjiva Bimal
We report here a Leishmania donovani ornithine decarboxylase (Ld-ODC) gene used as a DNA vaccine against visceral leishmaniasis in a murine Balb/c mouse model. This study also evaluated the possible mechanism of action directed by this candidate. We found a Th1 immune response after immunization using an Ld-ODC DNA vaccine, with results based on the rearrangement of TCR-V-α-2, proliferation of Carboxy fluorescein Succinimidyle ester positive T cells, which were able to produce cytokines such as TNF-α, IFN-γ, IL-12 and IL-2, but not IL-4, IL-5, IL-6 and IL-10, and modulations of the STAT-1 and p38 MAP kinase signaling pathways...
March 17, 2018: Molecular Immunology
Sarah T Ward, Justin B Dimick, Wenying Zhang, Darrell A Campbell, Amir A Ghaferi
OBJECTIVE: To identify hospital staffing models associated with failure to rescue (FTR) rates at low- and high-performing hospitals. BACKGROUND: FTR is an important quality measure in surgical safety and is a metric that hospitals are seeking to improve. Specific unit-level determinants of FTR, however, remain unknown. METHODS: Retrospective, observational study using data from the Michigan Quality Surgical Collaborative, which is a prospectively collected and clinically audited database in the state of Michigan...
March 19, 2018: Annals of Surgery
Hongbo Tan, Dean Wang, Amir H Lebaschi, Ian D Hutchinson, Liang Ying, Xiang-Hua Deng, Scott A Rodeo, Russell F Warren
BACKGROUND: Many orthopaedic surgical procedures involve reattachment of a single tendon to bone. Whether tendon-to-bone healing is better facilitated by tendon fixation within a bone tunnel or on a cortical surface is unknown. The purpose of this study was to evaluate tendon-healing within a bone tunnel compared with that on the cortical surface in a rabbit model of biceps tenodesis. METHODS: Thirty-two rabbits (24 weeks of age) underwent unilateral proximal biceps tenodesis with tendon fixation within a bone tunnel (BT group) or on the cortical surface (SA [surface attachment] group)...
March 21, 2018: Journal of Bone and Joint Surgery. American Volume
Mathilde Koch, Amir Pandi, Baudoin Delépine, Jean-Loup Faulon
The aim of this dataset is to identify and collect compounds that are known for being detectable by a living cell, through the action of a genetically encoded biosensor and is centred on bacterial transcription factors. Such a dataset should open the possibility to consider a wide range of applications in synthetic biology. The reader will find in this dataset the name of the compounds, their InChI (molecular structure), the publication where the detection was reported, the organism in which this was detected or engineered, the type of detection and experiment that was performed as well as the name of the biosensor...
April 2018: Data in Brief
Yuan Luo, Parinaz Abiri, Shell Zhang, Chih-Chiang Chang, Amir H Kaboodrangi, Rongsong Li, Ashish K Sahib, Alex Bui, Rajesh Kumar, Mary Woo, Zhaoping Li, René R Sevag Packard, Yu-Chong Tai, Tzung K Hsiai
Introduction: Obesity is associated with an increased risk of nonalcoholic fatty liver disease (NAFLD). While Magnetic Resonance Imaging (MRI) is a non-invasive gold standard to detect fatty liver, we demonstrate a low-cost and portable electrical impedance tomography (EIT) approach with circumferential abdominal electrodes for liver conductivity measurements. Methods and Results: A finite element model (FEM) was established to simulate decremental liver conductivity in response to incremental liver lipid content...
2018: Theranostics
Dong Liu, Adam Stowie, Nuria de Zavalia, Tanya Leise, Salil Saurav Pathak, Lester R Drewes, Alec J Davidson, Shimon Amir, Nahum Sonenberg, Ruifeng Cao
Mammalian/mechanistic target of rapamycin (mTOR) signaling controls cell growth, proliferation, and metabolism in dividing cells. Less is known regarding its function in postmitotic neurons in the adult brain. Here we created a conditional mTOR knockout mouse model to address this question. Using the Cre-LoxP system, the mTOR gene was specifically knocked out in cells expressing Vip (vasoactive intestinal peptide), which represent a major population of interneurons widely distributed in the neocortex, suprachiasmatic nucleus (SCN), olfactory bulb (OB), and other brain regions...
March 19, 2018: Proceedings of the National Academy of Sciences of the United States of America
Daphna Mezad-Koursh, Amir Rosenblatt, Hadas Newman, Chaim Stolovitch
PURPOSE: To evaluate the efficacy of the BinoVision home system as measured by improvement of visual acuity in the patient's amblyopic eye. METHODS: An open-label prospective pilot-trial of the system was conducted with amblyopic children aged 4-8 years at the pediatric ophthalmology unit, Tel-Aviv Medical Center, January 2014 to October 2015. Participants were assigned to the study or sham group for treatment with BinoVision for 8 or 12 weeks. Patients were instructed to watch animated television shows and videos at home using the BinoVision device for 60 minutes, 6 days a week...
March 16, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Amir Shaban, Toshio Moritani, Sami Al Kasab, Ali Sheharyar, Kaustubh S Limaye, Harold P Adams
BACKGROUND AND PURPOSE: Spinal cord hemorrhages are rare conditions that can be classified based on the primary location of bleeding into intramedullary (hematomyelia), subarachnoid hemorrhage (SAH), subdural hemorrhage, and epidural hemorrhage. We conducted a literature review to better understand the presenting symptoms, etiology, diagnosis, and treatment of spinal cord hemorrhages. METHODS: We performed a literature search using PubMed with the key words spinal hemorrhage, hematomyelia, spinal subarachnoid hemorrhage, spinal subdural hematoma, and spinal epidural hematoma RESULTS: Most commonly, spinal hematomas present with acute onset of pain and myelopathy but a more insidious course also may occur...
March 16, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Saba Eshraghi, Ibrahim Esat, Amir A Mohagheghi
BACKGROUND: Hallux Valgus (HV) is the most common fore-foot deformity, which causes foot pain and limited motion that are encountered in podiatric and orthopedic practices. The purpose of this study is to develop a reliable pattern recognition method to identify the presence of HV based on plantar force measurements. METHOD: Forces at five discrete metatarsal regions are measured at discrete time intervals under the right foot. Under this method, it is hypothesized that force measurement at a given time interval is related to the forces at a previous time interval by using Markovian transition matrix (T matrix)...
March 11, 2018: Gait & Posture
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