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https://www.readbyqxmd.com/read/28330293/effect-of-reduced-plant-height-on-drought-tolerance-in-rice
#1
Asadollah Ahmadikhah, Amir Marufinia
Drought stress due to water deficit is a major problem of rice cultivation as a most drought-sensitive crop plant. A rice mutant line (MT58) was developed after mutagenesis of cv. Neda by ethyl methane sulfonate (EMS) and selected for dwarfism (18 cm shorter than Neda). The extent of its molecular changes relative to parental cultivar was assessed by SSR and ISSR markers, and the response of the line along with parental cultivar and another mutant line (MTA) to mild and severe water deficit, was evaluated in a field experiment...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330155/purification-and-characterization-of-rga2-a-rho2-gtpase-activating-protein-from-tinospora-cordifolia
#2
Mohd Amir, Mohammad Aasif Dar, Wahiduzzaman, Asimul Islam, Faizan Ahmad, Md Imtaiyaz Hassan
Rho GTPases activating protein 2 (RGA2) is primarily involved in the modulation of numerous morphological events in eukaryotes. It protects plants by triggering the defense system which restricts the pathogen growth. This is the first report on the isolation, purification and characterization of RGA2 from the stems of Tinospora cordifolia, a medicinal plant. The RGA2 was purified using simple two-step process using DEAE-Hi-Trap FF and Superdex 200 chromatography columns, with a high yield. The purity of RGA2 was confirmed by SDS-PAGE and identified by MALDI-TOF/MS...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28329325/comparison-of-radial-and-bilateral-internal-thoracic-artery-grafting-in-patients-with-peripheral-vascular-disease%C3%A2
#3
Dmitry Pevni, Yanai Ben-Gal, Rephael Mohr, Nadav Teich, Zvi Raviv, Amir Kramer, Yosef Paz, Benjamin Medalion, Nahum Nesher
OBJECTIVES: The composite T-graft with radial artery (RA) attached end-to-side to the left internal thoracic artery (ITA) provides arterial myocardial revascularization without the increased risk of deep sternal wound infection associated with harvesting 2 ITAs. However, many surgeons are reluctant to use RA in patients with peripheral vascular disease (PVD) due to concerns regarding the quality of the conduit in this subset of patients. The purpose of this study is to compare early- and long-term outcomes of arterial grafting with bilateral ITAs (BITA) to that of single ITA and RA in patients with PVD...
March 2, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28327059/association-between-non-infectious-uveitis-and-thyroid-dysfunction-a-case-control-study
#4
Amir Rosenblatt, Hussein Zaitoon, Zohar Habot-Wilner
BACKGROUND: Several reports suggested a relation between uveitis and thyroid disease or dysfunction. However, no study has investigated the association between uveitis and thyroid dysfunction. The purpose of this study was to compare the prevalence of thyroid dysfunction in patients with and without non-infectious uveitis. METHODS: This was a retrospective, case-control study. RESULTS: Two hundred thirty-five non-infectious uveitis patients (uveitis group) and 600 controls (control group) were included in the study, of whom 492 (58...
March 22, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28325499/the-dorsal-language-pathways-in-stuttering-response-to-commentary
#5
Vered Kronfeld-Duenias, Ofer Amir, Ruth Ezrati-Vinacour, Oren Civier, Michal Ben-Shachar
No abstract text is available yet for this article.
February 20, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28325049/antibody-subclass-detection-using-graphene-nanopore
#6
Amir Barati Farimani, Mohammad Heiranian, Kyoungmin Min, Narayana R Aluru
Solid-state nanopores are promising for label free protein detection. The large thickness, ranging from several tens of nanometers to micrometers and larger, of solid-state nanopores prohibits atomic scale scanning or interrogation of proteins. Here, a single-atom thick graphene nanopore is shown to be highly capable of sensing and discriminating between different subclasses of IgG antibodies despite their minor and subtle variation in atomic structure. Extensive molecular dynamics (MD) simulations, rigorous statistical analysis with a total aggregate simulation time of 2...
March 21, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28324787/interactive-ebooks-in-educating-patients-and-their-families-about-head-injury-regardless-of-age
#7
Ronald Sahyouni, Amin Mahmoodi, Amir Mahmoodi, Melissa Huang, Diem Kieu Tran, Jefferson W Chen
OBJECTIVES: Traumatic Brain Injury (TBI) is a common and debilitating injury that is particularly prevalent in patients over 60. Given the influence of head injury on dementia (and vice versa), and the increased likelihood of ground-level falls, elderly patients are vulnerable to TBI. Educational interventions can increase knowledge and influence preventative activity to decrease the likelihood of further TBI. We sought to determine the efficacy of interactive tablet-based educational interventions in elderly patients on self-reported knowledge...
March 8, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28324223/adverse-neonatal-and-maternal-outcome-following-vacuum-assisted-vaginal-delivery-does-indication-matter
#8
Lina Salman, Amir Aviram, Eyal Krispin, Arnon Wiznitzer, Rony Chen, Rinat Gabbay-Benziv
PURPOSE: To estimate the impact of indication for vacuum-assisted vaginal delivery on neonatal and maternal adverse outcome. METHODS: Retrospective analysis of women carrying singleton-term pregnancies undergoing vacuum-assisted vaginal delivery in a tertiary hospital (2007-2014). Cohort was stratified by indication: non-reassuring fetal heart rate or prolonged second stage. Primary outcome was adverse neonatal outcome and secondary outcome was maternal morbidity...
March 21, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28323957/risk-profile-of-the-ret-a883f-germline-mutation-an-international-collaborative-study
#9
Jes Sloth Mathiesen, Mouhammed Amir Habra, John Howard Duncan Bassett, Sirazum Mubin Choudhury, Sabapathy Prakash Balasubramanian, Trevor A Howlett, Bruce G Robinson, Anne-Paule Gimenez-Roqueplo, Frederic Castinetti, Peter Vestergaard, Karin Frank-Raue
Context: The A883F germline mutation of the REarranged during Transfection proto-oncogene causes multiple endocrine neoplasia 2B. In the revised American Thyroid Association (ATA) guidelines for the management of medullary thyroid carcinoma (MTC) the A883F mutation has been reclassified from the highest to high risk level, although no well-defined risk profile for this mutation exists. Objective: To create a risk profile for the A883F mutation for appropriate classification in the ATA risk levels...
March 17, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323817/hippocampal-and-prefrontal-processing-of-network-topology-to-simulate-the-future
#10
Amir-Homayoun Javadi, Beatrix Emo, Lorelei R Howard, Fiona E Zisch, Yichao Yu, Rebecca Knight, Joao Pinelo Silva, Hugo J Spiers
Topological networks lie at the heart of our cities and social milieu. However, it remains unclear how and when the brain processes topological structures to guide future behaviour during everyday life. Using fMRI in humans and a simulation of London (UK), here we show that, specifically when new streets are entered during navigation of the city, right posterior hippocampal activity indexes the change in the number of local topological connections available for future travel and right anterior hippocampal activity reflects global properties of the street entered...
March 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28323493/microparticles-containing-erlotinib-loaded-solid-lipid-nanoparticles-for-treatment-of-non-small-cell-lung-cancer
#11
Zahra Bakhtiary, Jaleh Barar, Ayuob Aghanejad, Amir Ata Saei, Elhameh Nemati, Jafar Ezzati Nazhad Dolatabadi, Yadollah Omidi
Non-small cell lung cancer (NSCLC) patients with sensitizing mutations in the exons 18-21 of the epithelial growth factor receptor (EGFR) geneshowincreased kinase activity of EGFR. Hence, tyrosine kinase inhibitors (TKIs) such as erlotinib (ETB) havecommonly been used as the second line therapeutic option in metastatic NSCLC. While the ETB is available as an oral dosage form, the local delivery of this TKI to the diseased cells of the lung may ameliorate its therapeutic impacts. In the current study, we report on the development of ETB-loaded solid lipid nanoparticle (SLN) based formulation of dry powder inhaler (ETB-SLN DPI)...
March 21, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28322898/biliary-stent-migration-a-rare-cause-of-a-bladder-stone
#12
Neha R Malhotra, Carlos Amir Esparza Monzavi, Jean-Sebastien Trepanier, Johan Nordenstam, Michael R Abern
Our patient presented with dysuria and pneumaturia without any prior urologic instrumentation. History included choledocolithiasis requiring ERCP and biliary stenting. Imaging showed a large bladder stone. She was taken to surgery and found to have diverticulitis. The sigmoid was resected and the bladder found to have a small fistula tract. The bladder was opened and a large calculus was identified and extracted. The stone was opened and found to contain a biliary stent. While biliary stenting is generally considered safe, migration can occur...
March 17, 2017: Urology
https://www.readbyqxmd.com/read/28320483/human-and-feline-adipose-derived-mesenchymal-stem-cells-have-comparable-phenotype-immunomodulatory-functions-and-transcriptome
#13
Kaitlin C Clark, Fernando A Fierro, Emily Mills Ko, Naomi J Walker, Boaz Arzi, Clifford G Tepper, Heather Dahlenburg, Andrew Cicchetto, Amir Kol, Lyndsey Marsh, William J Murphy, Nasim Fazel, Dori L Borjesson
BACKGROUND: Adipose-derived mesenchymal stem cells (ASCs) are a promising cell therapy to treat inflammatory and immune-mediated diseases. Development of appropriate pre-clinical animal models is critical to determine safety and attain early efficacy data for the most promising therapeutic candidates. Naturally occurring diseases in cats already serve as valuable models to inform human clinical trials in oncologic, cardiovascular, and genetic diseases. The objective of this study was to complete a comprehensive side-by-side comparison of human and feline ASCs, with an emphasis on their immunomodulatory capacity and transcriptome...
March 20, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28320185/the-antiepileptogenic-effect-of-low-frequency-stimulation-on-perforant-path-kindling-involves-changes-in-regulators-of-g-protein-signaling-in-rat
#14
Simin Namvar, Yaghoub Fathollahi, Mohammad Javan, Maryam Zeraati, Mohammad Mohammad-Zadeh, Amir Shojaei, Javad Mirnajafi-Zadeh
G-protein coupled receptors may have a role in mediating the antiepileptogenic effect of low-frequency stimulation (LFS) on kindling acquisition. This effect is accompanied by changes at the intracellular level of cAMP. In the present study, the effect of rolipram as a phosphodiesterase inhibitor on the antiepileptogenic effect of LFS was investigated. Meanwhile, the expression of αs- and αi-subunit of G proteins and regulators of G-protein signaling (RGS) proteins following LFS application was measured. Male Wistar rats were kindled by perforant path stimulation in a semi-rapid kindling manner (12 stimulations per day) during a period of 6days...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320099/light-emitting-diode-led-therapy-improves-occipital-cortex-damage-by-decreasing-apoptosis-and-increasing-bdnf-expressing-cells-in-methanol-induced-toxicity-in-rats
#15
Amir Ghanbari, Majid Ghareghani, Kazem Zibara, Hamdallah Delaviz, Elham Ebadi, Mohammad Hossein Jahantab
Methanol-induced retinal toxicity, frequently associated with elevated free radicals and cell edema, is characterized by progressive retinal ganglion cell (RGC) death and vision loss. Previous studies investigated the effect of photomodulation on RGCs, but not the visual cortex. In this study, the effect of 670nm Light-Emitting Diode (LED) therapy on RGCs and visual cortex recovery was investigated in a seven-day methanol-induced retinal toxicity protocol in rats. Methanol administration showed a reduction in the number of RGCs, loss of neurons (neuronal nuclear antigen, NeuN+), activation of glial fibrillary acidic protein (GFAP+) expressing cells, suppression of brain-derived neurotrophic factor (BDNF+) positive cells, increase in apoptosis (caspase 3+) and enhancement of nitric oxide (NO) release in serum and brain...
March 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28319598/allium-vegetable-intakes-and-the-incidence-of-cardiovascular-disease-hypertension-chronic-kidney-disease-and-type-2-diabetes-in-adults-a-longitudinal-follow-up-study
#16
Zahra Bahadoran, Parvin Mirmiran, Amir A Momenan, Fereidoun Azizi
OBJECTIVES: This study investigated the association between habitual consumption of allium vegetables (garlic and onion) and the incidence of cardiovascular disease (CVD) outcomes, hypertension (HTN), chronic kidney disease (CKD), and type 2 diabetes (T2D). METHODS: Adult men and women, participated in the Tehran Lipid and Glucose Study (2006-2008 to 2012-2014), were recruited. Habitual dietary intakes were assessed using a validated semiquantitative food frequency questionnaire...
March 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28319515/a-perioperative-smoking-cessation-intervention-with-varenicline-counseling-and-fax-referral-to-a-telephone-quitline-versus-a-brief-intervention-a-randomized-controlled-trial
#17
Jean Wong, Amir Abrishami, Sheila Riazi, Naveed Siddiqui, Eric You-Ten, Jennifer Korman, Sazzadul Islam, Xin Chen, Maged S M Andrawes, Peter Selby, David T Wong, Frances Chung
BACKGROUND: The effectiveness of perioperative interventions to quit smoking with varenicline has not been compared with brief interventions. Our objective was to determine the efficacy of a comprehensive smoking cessation program versus a brief intervention for smoking cessation. METHODS: In this prospective, multicenter study, 296 patients were randomized to participate in a smoking cessation program (one 10- to 15-minute counseling session, pharmacotherapy with varenicline, an educational pamphlet, and a fax referral to a telephone quitline); or brief advice and self-referral to a telephone quitline...
March 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28319087/erratum-model-based-projections-of-zika-virus-infections-in-childbearing-women-in-the-americas
#18
T Alex Perkins, Amir S Siraj, Corrine W Ruktanonchai, Moritz U G Kraemer, Andrew J Tatem
No abstract text is available yet for this article.
March 20, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28318546/robust-state-estimation-for-a-class-of-uncertain-nonlinear-systems-comparison-of-two-approaches
#19
Amir Abbasi, Javad Poshtan
In this paper, two approaches for robust state estimation of a class of Lipschitz nonlinear systems are proposed. First, a novel Unknown Input Observer (UIO) is designed without observer matching condition satisfaction. Then, an H∞ observer for approximate disturbance decoupling is proposed. Sufficient conditions for the existence of both proposed observers are derived based on a Lyapunov function. The achieved conditions are formulated in terms of a set of linear matrix inequalities (LMIs) and optimal gain matrices are obtained...
March 16, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28317403/intrahepatic-cholangiocarcinoma-current-management-and-emerging-therapies
#20
Amir A Rahnemai-Azar, Allison B Weisbrod, Mary Dillhoff, Carl Schmidt, Timothy M Pawlik
Intrahepatic cholangiocarcinoma (iCCA) is a malignancy with an increasing incidence and a high-case fatality. While surgery offers the best hope at long-term survival, only one-third of tumors are amenable to surgical resection at the time of the diagnosis. Unfortunately, conventional chemotherapy offers limited survival benefit in the management of unresectable or metastatic disease. Recent advances in understanding the molecular pathogenesis of iCCA and the use of next-generation sequencing techniques have provided a chance to identify "target-able" molecular aberrations...
March 20, 2017: Expert Review of Gastroenterology & Hepatology
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