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Developmental coordination

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https://www.readbyqxmd.com/read/28444245/can-a-community-of-practice-improve-physical-therapists-self-perceived-practice-in-developmental-coordination-disorder
#1
Chantal Camden, Lisa M Rivard, Karen Hurtubise, Léa Héguy, Jade Berbari
Background: Communities of practice (CoP ) are useful knowledge translation (KT) strategies but little is known about their impact on physical therapists' (PTs) self-perceived practice. Purpose: We evaluated the impact of a CoP on PTs' self-perceived practice, and explored factors influencing changes in self-perceived knowledge, skills, and practice related to developmental coordination disorder (DCD). Design: We used an explanatory sequential mixed-methods design, guided by The Theory of Reasoned Action and Theory of Planned Behavior...
April 21, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28444104/psychomotor-ability-and-short-term-memory-and-reading-and-mathematics-achievement-in-children
#2
Cherée Murrihy, Maria Bailey, John Roodenburg
Objective: The aim of our study was to examine whether the findings from previous research, indicating the role of short-term memory as a mediator of the relationship between motor coordination and academic achievement in adolescents, is also evident in a younger child population. Method: The study utilized a quantative cross-sectional design involving 133 children aged 8-12. The McCarron Assessment of Neuromuscular Development (MAND) provided four indicators of psychomotor ability (Finger Nose, Walking, Balancing, and Jumping)...
April 24, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28440058/atypical-inter-hemispheric-communication-correlates-with-altered-motor-inhibition-during-learning-of-a-new-bimanual-coordination-pattern-in-developmental-coordination-disorder
#3
Mélody Blais, David Amarantini, Jean-Michel Albaret, Yves Chaix, Jessica Tallet
Impairment of motor learning skills in developmental coordination disorder (DCD) has been reported in several studies. Some hypotheses on neural mechanisms of motor learning deficits in DCD have emerged but, to date, brain-imaging investigations are scarce. The aim of the present study is to assess possible changes in communication between brain areas during practice of a new bimanual coordination task in teenagers with DCD (n = 10) compared to matched controls (n = 10). Accuracy, stability and number of mirror movements were computed as behavioural variables...
April 25, 2017: Developmental Science
https://www.readbyqxmd.com/read/28439231/informing-the-structure-of-executive-function-in-children-a-meta-analysis-of-functional-neuroimaging-data
#4
Róisín McKenna, T Rushe, Kate A Woodcock
The structure of executive function (EF) has been the focus of much debate for decades. What is more, the complexity and diversity provided by the developmental period only adds to this contention. The development of executive function plays an integral part in the expression of children's behavioral, cognitive, social, and emotional capabilities. Understanding how these processes are constructed during development allows for effective measurement of EF in this population. This meta-analysis aims to contribute to a better understanding of the structure of executive function in children...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28435745/a-consult-service-to-support-and-promote-community-based-research-tracking-and-evaluating-a-community-based-research-consult-service
#5
Clara M Pelfrey, Katrice D Cain, Mary Ellen Lawless, Earl Pike, Ashwini R Sehgal
PURPOSE: This study describes the design, operation and evaluation of a community-based research (CBR) consult service within the setting of a Clinical and Translational Science Award (CTSA) institution. To our knowledge, there are no published evaluations of a CBR consult service at a CTSA hub. METHODS: A community-based research Consult Service was created to support faculty, health care providers/research coordinators, trainees, community-based organizations and community members...
February 2017: J Clin Transl Sci
https://www.readbyqxmd.com/read/28428287/smurf-downregulates-echinoid-in-the-amnioserosa-to-regulate-drosophila-dorsal-closure
#6
Chiao-Ming Lin, Jiajun Xu, Wen-Ting Yang, Chao Wang, Yu-Chiao Li, Lien-Chieh Cheng, Lei Zhang, Jui-Chou Hsu
Drosophila dorsal closure is a morphogenetic movement that involves flanking epidermal cells, assembling actomyosin cables and migrating dorsally over the underlying amnioserosa to seal at the dorsal midline. Echinoid (Ed), a cell adhesion molecule of adherens junctions (AJs), participates in several developmental processes. The disappearance of Ed from the amnioserosa is required to define the epidermal leading edge for actomyosin cable assembly and coordinated cell migration. However, the mechanism by which Ed is cleared from amnioserosa is unknown...
April 19, 2017: Genetics
https://www.readbyqxmd.com/read/28425731/changes-in-perception-action-tuning-over-long-time-scales-how-children-and-adults-perceive-and-act-on-dynamic-affordances-when-crossing-roads
#7
Elizabeth E O'Neal, Yuanyuan Jiang, Lucas J Franzen, Pooya Rahimian, Junghum Paul Yon, Joseph K Kearney, Jodie M Plumert
This investigation examined developmental change in how children perceive and act on dynamic affordances when crossing roads on foot. Six- to 14-year-olds and adults crossed roads with continuous cross-traffic in a large-screen, immersive pedestrian simulator. We observed change both in children's gap choices and in their ability to precisely synchronize their movement with the opening of a gap. Younger children were less discriminating than older children and adults, choosing fewer large gaps and more small gaps...
April 20, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28424623/notch-signaling-in-ischemic-damage-and-fibrosis-evidence-and-clues-from-the-heart
#8
REVIEW
Silvia Nistri, Chiara Sassoli, Daniele Bani
Notch signaling is a major intercellular coordination mechanism highly conserved throughout evolution. In vertebrates, Notch signaling is physiologically involved in embryo development, including mesenchymal cell commitment, formation of heart tissues and angiogenesis. In post-natal life, Notch signaling is maintained as a key mechanism of cell-cell communication and its dysregulations have been found in pathological conditions such as ischemic and fibrotic diseases. In the heart, Notch takes part in the protective response to ischemia, being involved in pre- and post-conditioning, reduction of reperfusion-induced oxidative stress and myocardial damage, and cardiomyogenesis...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28424177/developmental-and-behavioural-associations-of-burns-and-scalds-in-children-a-prospective-population-based-study
#9
Alan Emond, Clare Sheahan, Julie Mytton, Linda Hollén
OBJECTIVE: To investigate child developmental and behavioural characteristics and risk of burns and scalds. DESIGN: Data on burns in children up to 11 years from 12 966 participants in the Avon Longitudinal Study of Parents and Children were linked to developmental profiles measured before the burn injury. MEASURES: Preinjury profiles of the children derived from maternal questionnaires completed in pregnancy, and at 6, 18, 42, 47 and 54 months...
May 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28419906/plant-hormone-signaling-in-flowering-an-epigenetic-point-of-view
#10
REVIEW
Gerardo Campos-Rivero, Pedro Osorio-Montalvo, Rafael Sánchez-Borges, Rosa Us-Camas, Fátima Duarte-Aké, Clelia De-la-Peña
Reproduction is one of the most important phases in an organism's lifecycle. In the case of angiosperm plants, flowering provides the major developmental transition from the vegetative to the reproductive stage, and requires genetic and epigenetic reprogramming to ensure the success of seed production. Flowering is regulated by a complex network of genes that integrate multiple environmental cues and endogenous signals so that flowering occurs at the right time; hormone regulation, signaling and homeostasis are very important in this process...
March 31, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28415049/metamorphosis-and-transition-between-developmental-stages-in-european-eel-anguilla-anguilla-l-involve-epigenetic-changes-in-dna-methylation-patterns
#11
Jochen H Trautner, Stefan Reiser, Tina Blancke, Katrin Unger, Klaus Wysujack
The life history of the European eel (Anguilla anguilla, L.) is characterized by a series of metamorphoses and transitions that provoke drastic morphological changes. Most of these changes go along with the catadromous life cycle in eels, involving extensive physiologically adaptations. In this study it was investigated whether these drastic changes have an epigenetic basis by analyzing global methylation patterns in liver, gill and brain tissue from glass eels caught at the British coast as well as yellow and silver eels from River Rhine using methylation-sensitive amplified polymorphisms (MSAP)...
April 6, 2017: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/28412469/earliest-phases-of-chondrogenesis-are-dependent-upon-angiogenesis-during-ectopic-bone-formation-in-mice
#12
Beth Bragdon, Stephanie Lam, Sherif Aly, Alexandra Femia, Abigail Clark, Amira Hussein, Elise F Morgan, Louis C Gerstenfeld
Endochondral ossification is the process where cartilage forms prior to ossification and in which new bone forms during both fracture healing and ectopic bone formation. Transitioning to ossification is a highly coordinated process between hypertrophic chondrocytes, vascular endothelial cells, osteoblasts and osteoclasts. A critical biological process that is central to the interactions of these various cell types is angiogenesis. Although it is well established that angiogenesis is crucial for fracture repair, less is known pertaining to the role of angiogenesis in ectopic bone formation...
April 12, 2017: Bone
https://www.readbyqxmd.com/read/28409696/collaborative-occupational-therapy-teachers-impressions-of-the-partnering-for-change-p4c-model
#13
A L Wilson, S R Harris
AIMS: Occupational therapists (OTs) often face barriers when trying to collaborate with teachers in school-based settings. Partnering for change (P4C), a collaborative practice model designed to support children with developmental coordination disorder, could potentially support all students with special needs. Therefore, the aim of this study was to explore how teachers experience OT services delivered using the P4C model to support children with a variety of special needs. METHODS: P4C was implemented at one elementary school in Courtenay, British Columbia...
April 14, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/28407444/familial-18q12-2-deletion-supports-the-role-of-rna-binding-protein-celf4-in-autism-spectrum-disorders
#14
Rita Barone, Marco Fichera, Mariaclara De Grandi, Marta Battaglia, Valeria Lo Faro, Teresa Mattina, Renata Rizzo
Deletion of 18q12.2 is an increasingly recognized condition with a distinct neuropsychiatric phenotype. Twenty-two patients have been described with overlapping neurobehavioral disturbances including developmental delay, intellectual disability of variable degree, seizures, motor coordination disorder, behavioral/emotional disturbances, and autism spectrum disorders. The CUGBP Elav-like family member 4 (CELF4) gene at 18q12.2 encodes a RNA-binding protein that links to RNA subsets involved in pre- and postsynaptic neurotransmission including almost 30% of potential autism-related genes...
April 13, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28404867/dynamic-cellular-finite-element-method-for-modelling-large-scale-cell-migration-and-proliferation-under-the-control-of-mechanical-and-biochemical-cues-a-study-of-re-epithelialization
#15
Jieling Zhao, Youfang Cao, Luisa A DiPietro, Jie Liang
Computational modelling of cells can reveal insight into the mechanisms of the important processes of tissue development. However, current cell models have limitations and are challenged to model detailed changes in cellular shapes and physical mechanics when thousands of migrating and interacting cells need to be modelled. Here we describe a novel dynamic cellular finite-element model (DyCelFEM), which accounts for changes in cellular shapes and mechanics. It also models the full range of cell motion, from movements of individual cells to collective cell migrations...
April 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28404643/the-beach-containing-protein-wdr81-coordinates-p62-and-lc3c-to-promote-aggrephagy
#16
Xuezhao Liu, Yang Li, Xin Wang, Ruxiao Xing, Kai Liu, Qiwen Gan, Changyong Tang, Zhiyang Gao, Youli Jian, Shouqing Luo, Weixiang Guo, Chonglin Yang
Autophagy-dependent clearance of ubiquitinated and aggregated proteins is critical to protein quality control, but the underlying mechanisms are not well understood. Here, we report the essential role of the BEACH (beige and Chediak-Higashi) and WD40 repeat-containing protein WDR81 in eliminating ubiquitinated proteins through autophagy. WDR81 associates with ubiquitin (Ub)-positive protein foci, and its loss causes accumulation of Ub proteins and the autophagy cargo receptor p62. WDR81 interacts with p62, facilitating recognition of Ub proteins by p62...
April 12, 2017: Journal of Cell Biology
https://www.readbyqxmd.com/read/28402479/perception-of-social-synchrony-induces-mother-child-gamma-coupling-in-the-social-brain
#17
Jonathan Levy, Abraham Goldstein, Ruth Feldman
The recent call to move from focus on one brain's functioning to two-brain communication initiated a search for mechanisms that enable two humans to coordinate brain response during social interactions. Here, we utilized the mother-child context as a developmentally salient setting to study two-brain coupling. Mothers and their 9-year-old children were videotaped at home in positive and conflictual interactions. Positive interactions were microcoded for social synchrony and conflicts for overall dialogical style...
April 11, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28399923/making-good-on-a-call-to-expand-method-choice-for-young-people-turning-rhetoric-into-reality-for-addressing-sustainable-development-goal-three
#18
Fariyal Fatma Fikree, Catharine Lane, Callie Simon, Gwyn Hainsworth, Patricia MacDonald
BACKGROUND: Investments in the nearly two billion young people, aged 10-24 years, in the world today are necessary to meet global development commitments, specifically the Sustainable Development Goals and Ending Preventable Child and Maternal Deaths. More than 12 million married and unmarried adolescents (aged 15-19) will give birth in 2016. Complications of pregnancy and childbirth are the second leading cause of death among 15-19 year-old women and early childbearing can significantly curtail social and economic prospects for young women...
April 11, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28392009/genitourinary-and-gastrointestinal-co-morbidities-in-children-the-role-of-neural-circuits-in-regulation-of-visceral-function
#19
REVIEW
A P Malykhina, K E Brodie, D T Wilcox
OBJECTIVE: Pediatric lower urinary tract dysfunction (LUTD) is a common problem in childhood. Lower urinary tract symptoms in children include overactive bladder, voiding postponement, stress incontinence, giggle incontinence, and dysfunctional voiding. Gastrointestinal co-morbidities, including constipation or fecal incontinence, are commonly associated with lower urinary tract (LUT) symptoms in children, often reaching 22-34%. This review summarized the potential mechanisms underlying functional lower urinary and gastrointestinal co-morbidities in children...
June 15, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28389751/heat-shock-protein-a2-hspa2-regulatory-roles-in-germ-cell-development-and-sperm-function
#20
Brett Nixon, Elizabeth G Bromfield, Jinwei Cui, Geoffry N De Iuliis
Among the numerous families of heat shock protein (HSP) that have been implicated in the regulation of reproductive system development and function, those belonging to the 70 kDa HSP family have emerged as being indispensable for male fertility. In particular, the testis-enriched heat shock 70 kDa protein 2 (HSPA2) has been shown to be critical for the progression of germ cell differentiation during spermatogenesis in the mouse model. Beyond this developmentally important window, mounting evidence has also implicated HSPA2 in the functional transformation of the human sperm cell during their ascent of the female reproductive tract...
2017: Advances in Anatomy, Embryology, and Cell Biology
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