keyword
MENU ▼
Read by QxMD icon Read
search

Functional movement

keyword
https://www.readbyqxmd.com/read/29346624/data-driven-approaches-to-define-the-upper-limit-of-the-inter-movement-interval-of-periodic-leg-movements-during-sleep
#1
Raffaele Ferri, Alessandro Silvani, Francesco Rundo, Marco Zucconi, Debora Aricò, Oliviero Bruni, Luigi Ferini-Strambi, Mauro Manconi
Objective: to define statistically the upper limit of the inter-movement interval (IMI, the time interval between the onset of consecutive movements) of periodic leg movements during sleep (PLMS). Subjects and Methods: we computed the IMI distribution of a large sample (n = 141) of patients with restless legs syndrome (RLS) and analyzed it with two independent approaches, based on fitting either empirical functions or normal and exponential functions to the data...
January 13, 2018: Sleep
https://www.readbyqxmd.com/read/29346549/transcriptome-and-functional-analysis-in-a-drosophila-model-of-ngly1-deficiency-provides-insight-into-therapeutic-approaches
#2
Katie G Owings, Joshua B Lowry, Yiling Bi, Matthew Might, Clement Y Chow
Autosomal recessive loss-of-function mutations in N-Glycanase 1 (NGLY1) cause NGLY1 deficiency, the only known human disease of deglycosylation. Patients present with developmental delay, movement disorder, seizures, liver dysfunction, and alacrima. NGLY1 is a conserved cytoplasmic component of the Endoplasmic Reticulum Associated Degradation (ERAD) pathway. ERAD clears misfolded proteins from the ER lumen. However, it is unclear how loss of NGLY1 function impacts ERAD and other cellular processes and results in the constellation of problems associated with NGLY1 deficiency...
January 15, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29346490/composition-architecture-and-functional-implications-of-the-connective-tissue-network-of-the-extraocular-muscles
#3
Linda K McLoon, André Vicente, Krysta R Fitzpatrick, Mona Lindström, Fatima Pedrosa Domellöf
Purpose: We examined the pattern and extent of connective tissue distribution in the extraocular muscles (EOMs) and determined the ability of the interconnected connective tissues to disseminate force laterally. Methods: Human EOMs were examined for collagens I, III, IV, and VI; fibronectin; laminin; and elastin using immunohistochemistry. Connective tissue distribution was examined with scanning electron microscopy. Rabbit EOMs were examined for levels of force transmission longitudinally and transversely using in vitro force assessment...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29346370/structure-function-and-control-of-the-human-musculoskeletal-network
#4
Andrew C Murphy, Sarah F Muldoon, David Baker, Adam Lastowka, Brittany Bennett, Muzhi Yang, Danielle S Bassett
The human body is a complex organism, the gross mechanical properties of which are enabled by an interconnected musculoskeletal network controlled by the nervous system. The nature of musculoskeletal interconnection facilitates stability, voluntary movement, and robustness to injury. However, a fundamental understanding of this network and its control by neural systems has remained elusive. Here we address this gap in knowledge by utilizing medical databases and mathematical modeling to reveal the organizational structure, predicted function, and neural control of the musculoskeletal system...
January 2018: PLoS Biology
https://www.readbyqxmd.com/read/29346082/distal-upper-limb-kinematics-during-functional-everyday-tasks
#5
Ben Stansfield, Scott Rooney, Lisa Brown, Matthew Kay, Lisa Spoettl, Shivaramkumar Shanmugam
Quantitative characterisation of upper limb motion allows the evaluation of the effect of pathology on functional task performance, potentially directing rehabilitation strategies. Movement patterns of the distal upper limb in healthy adults during functional tasks have not been extensively characterised. During five loaded functional tasks (drinking from a glass, pouring from a kettle, turning a handle, lifting a bag to a shelf, turning a key) the movement patterns were characterised using three-dimensional motion analysis with a minimal marker set in 16 healthy adults (10 M,6F, 27 (IQR:25-43)years)...
January 10, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29346081/reported-balance-confidence-and-movement-reinvestment-of-younger-knee-replacement-patients-are-more-like-younger-healthy-individuals-than-older-patients
#6
Brian D Street, Allan Adkin, William Gage
This study focused on differences between the rapidly growing younger (<65 years old) and older (>65 years old) total knee replacement (TKR) patients for measures of balance confidence, movement reinvestment, and functional mobility. Fifty-nine participants, including twenty-nine primary unilateral TKR patients (six months post-TKR) formed the four experimental groups: 1) Younger TKR Patient (YP), 2) Younger Control (YC), 3) Older TKR Patient (OP), and 4) Older Control (OC). The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Oxford Knee Score (OKS), Activities-specific Balance Confidence scale (ABC), the Movement-Specific Reinvestment Scale (MSRS), and the Timed Up and Go (TUG) test were measured...
January 11, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29345555/the-preparation-period-in-basketball-training-load-and-neuromuscular-adaptations
#7
Davide Ferioli, Andrea Bosio, Johann C Bilsborough, Antonio La Torre, Michele Tornaghi, Ermanno Rampinini
PURPOSE: To investigate the 1) effect of the preparation period on the neuromuscular characteristics of 12 professional (PRO) and 16 semi-professional (SEMI-PRO) basketball players; 2) relationships between training load indices and changes in neuromuscular physical performance. METHODS: Prior to and following the preparation period, players underwent a counter-movement jump (CMJ) test, followed by a repeated change of direction (COD) test consisting of 4 levels with increasing intensities...
January 18, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29344939/socially-informed-dispersal-in-a-territorial-cooperative-breeder
#8
Gabriele Cozzi, Nino Maag, Luca Börger, Tim Clutton-Brock, Arpat Ozgul
1.Dispersal is a key process governing the dynamics of socially and spatially structured populations, and involves three distinct stages: emigration, transience, and settlement. At each stage, individuals have to make movement decisions, which are influenced by social, environmental, and individual factors. Yet, a comprehensive understanding of the drivers that influence such decisions is still lacking, particularly for the transient stage during which free-living individuals are inherently difficult to follow...
January 18, 2018: Journal of Animal Ecology
https://www.readbyqxmd.com/read/29344871/laser-capture-microdissection-for-layer-specific-analysis-of-enteric-ganglia
#9
Corinna Rosenbaum, Martina Böttner, Thilo Wedel, Marco Metzger
The enteric nervous system (ENS) is the division of the autonomic nervous system that innervates the gastrointestinal (GI) tract and controls central intestinal functions such as peristalsis and fluid movement. Enteric nerve cell bodies (neurons and glia) are predominantly organized in ganglionated networks that are present along the entire length of the GI tract in multiple tissue layers. Most cell bodies are organized in the myenteric plexus allocated between the longitudinal and the circular muscle layers or in the submucosal plexus between muscle tissue and mucosa...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29344835/genetic-evidence-for-the-role-of-a-rice-vacuolar-invertase-as-a-molecular-sink-strength-determinant
#10
Shamitha Rao Morey, Tatsuro Hirose, Yoichi Hashida, Akio Miyao, Hirohiko Hirochika, Ryu Ohsugi, Junko Yamagishi, Naohiro Aoki
BACKGROUND: Rice is a major crop feeding the majority of the global population, and increasing its sink strength is one of the modes to alleviate the declining availability of food for the rapidly growing world population. We demonstrate a role for an important rice vacuolar invertase isoform, OsINV3, in sink strength determination. RESULTS: OsINV3 mutants showed shorter panicles with lighter and smaller grains, owing to a smaller cell size on the outer and inner surfaces of the palea and lemma as observed by scanning electron microscopy...
January 17, 2018: Rice
https://www.readbyqxmd.com/read/29344775/new-saliva-secretion-model-based-on-the-expression-of-na-k-pump-and-k-channels-in-the-apical-membrane-of-parotid-acinar-cells
#11
János Almássy, Elias Siguenza, Marianna Skaliczki, Klara Matesz, James Sneyd, David I Yule, Péter P Nánási
The plasma membrane of parotid acinar cells is functionally divided into apical and basolateral regions. According to the current model, fluid secretion is driven by transepithelial ion gradient, which facilitates water movement by osmosis into the acinar lumen from the interstitium. The osmotic gradient is created by the apical Cl- efflux and the subsequent paracellular Na+ transport. In this model, the Na+-K+ pump is located exclusively in the basolateral membrane and has essential role in salivary secretion, since the driving force for Cl- transport via basolateral Na+-K+-2Cl- cotransport is generated by the Na+-K+ pump...
January 17, 2018: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/29344693/triplet-based-codon-organization-optimizes-the-impact-of-synonymous-mutation-on-nucleic-acid-molecular-dynamics
#12
Gregory A Babbitt, Erin E Coppola, Jamie S Mortensen, Patrick X Ekeren, Cosmo Viola, Dallan Goldblatt, André O Hudson
Since the elucidation of the genetic code almost 50 years ago, many nonrandom aspects of its codon organization remain only partly resolved. Here, we investigate the recent hypothesis of 'dual-use' codons which proposes that in addition to allowing adjustment of codon optimization to tRNA abundance, the degeneracy in the triplet-based genetic code also multiplexes information regarding DNA's helical shape and protein-binding dynamics while avoiding interference with other protein-level characteristics determined by amino acid properties...
January 17, 2018: Journal of Molecular Evolution
https://www.readbyqxmd.com/read/29344657/effects-of-hereditary-moderate-high-fat-diet-on-metabolic-performance-and-physical-endurance-capacity-in-c57bl-6-offspring
#13
Fang Liu, Guirong Zhang, Xue Sheng, Shang Liu, Meng Cui, Heyun Guo, Jianbin Xue, Lingyun Zhang
Obesity in pregnant women presents a risk to fetal health, leading to numerous metabolic syndromes and chronic inflammation risks. Previously, physical exercise was considered to be one of the primary treatments for obesity. However, the effect of fat consumption throughout the life cycle on physical endurance capacity remains unknown. A total of two groups of female mice (age, 6 weeks; C57BL/6J) were fed with a normal chow diet and a moderate high fat diet (MHFD), during pregnancy and lactation (8 weeks), with the offspring receiving the same diet as the mother...
January 16, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29343895/why-borrow-from-peter-when-paul-can-afford-it-reverse-homodigital-artery-flap-for-fingertip-reconstruction
#14
Narayanamurthy Sundaramurthy, Surya Rao Rao Venkata Mahipathy, Alagar Raja Durairaj
Background: Fingertip injuries that are complicated by pulp loss, bone or tendon exposure will need a flap cover. Cross finger flap is commonly used to cover such defects. However, patients are apprehensive about injuring the uninjured finger as a donor site. Reverse homodigital artery flap (RHAF) can provide reliable vascularised cover to such defects. Aims: This study aims to assess the functional and aesthetic outcomes along with the patient satisfaction of RHAFs done for fingertip defects...
May 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29343888/medial-femoral-condyle-vascularised-corticoperiosteal-graft-a-suitable-choice-for-scaphoid-non-union
#15
Samir Kumta, Sudhir Warrier, Leena Jain, Rani Ummal, Manik Menezes, Shrirang Purohit
Introduction: Scaphoid fractures are not very common and frequently remain undiagnosed, presenting in non-union and persistent wrist pain. Options for scaphoid fracture treatment have been described over several decades, however, none with an optimal solution to achieve union along with good hand function. We describe here, the use of vascularised corticoperiosteal bone grafts from the medial femoral condyle (MFC) as a solution for the difficult problem of scaphoid fracture non-union...
May 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29343751/altered-power-spectral-density-in-the-resting-state-sensorimotor-network-in-patients-with-myotonic-dystrophy-type-1
#16
Jin-Sung Park, Jeehye Seo, Hyunsil Cha, Hui-Jin Song, Sang-Hoon Lee, Kyung Eun Jang, Hui Joong Lee, Juyoung Park, Ho-Won Lee, Yongmin Chang
Myotonic dystrophy type 1 (DM1) is a multisystemic disease that involves the brain with several neurological symptoms. Although there were few imaging studies on DM1, no studies have investigated functional alterations in the sensorimotor network at rest in patients with DM1. In the current study, a power spectral density (PSD) analysis of resting-state fMRI data was performed to assess possible alteration in spontaneous neural activity of the sensorimotor network in patients with DM1. Compared to healthy controls, patients with DM1 showed higher PSD responses in the orbitofrontal cortex, parahippocampus and basal ganglia (corrected P < 0...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343645/crystal-structure-of-the-mammalian-lipopolysaccharide-detoxifier
#17
Alexei Gorelik, Katalin Illes, Bhushan Nagar
LPS is a potent bacterial endotoxin that triggers the innate immune system. Proper recognition of LPS by pattern-recognition receptors requires a full complement of typically six acyl chains in the lipid portion. Acyloxyacyl hydrolase (AOAH) is a host enzyme that removes secondary (acyloxyacyl-linked) fatty acids from LPS, rendering it immunologically inert. This activity is critical for recovery from immune tolerance that follows Gram-negative infection. To understand the molecular mechanism of AOAH function, we determined its crystal structure and its complex with LPS...
January 17, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29342047/direction-fixed-and-direction-changing-positional-nystagmus-in-ramsay-hunt-syndrome
#18
Chang-Hee Kim, Jin Woo Choi, Kyu Jin Han, Yong Sik Lee, Jung Eun Shin
OBJECTIVES: To investigate the incidence of positional nystagmus (PN) using a head-roll test in patients with Ramsay Hunt syndrome with vertigo (RHS_V) and discuss possible mechanisms. STUDY DESIGN: Retrospective study. SETTING: Tertiary referral academic medical center. PATIENTS: Twenty-eight patients with RHS_V were enrolled. MAIN OUTCOME MEASURE: Eye movements were recorded at positions of head roll to the right or left, and PN was classified as direction-fixed or direction-changing...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29341130/mitochondrial-function-and-autophagy-integrating-proteotoxic-redox-and-metabolic-stress-in-parkinson-s-disease
#19
REVIEW
Jianhua Zhang, M Lillian Culp, Jason G Craver, Victor Darley-Usmar
Parkinson's disease (PD) is a movement disorder with widespread neurodegeneration in the brain. Significant oxidative, reductive, metabolic, and proteotoxic alterations have been observed in PD postmortem brains. The alterations of mitochondrial function resulting in decreased bioenergetic health is important and needs to be further examined to help develop biomarkers for PD severity and prognosis. It is now becoming clear that multiple hits on metabolic and signaling pathways are likely to exacerbate PD pathogenesis...
January 17, 2018: Journal of Neurochemistry
https://www.readbyqxmd.com/read/29339981/using-bilateral-functional-and-anthropometric-tests-to-define-symmetry-in-cross-country-skiers
#20
Glenn Björklund, Marie Alricsson, Ulla Svantesson
The aim of this study was to evaluate the symmetry of anthropometry and muscle function in cross-country skiers and their association to vertical jumping power. Twenty cross-country skiers were recruited (21.7 ± 3.8 yrs, 180.6 ± 7.6 cm, 73.2 ± 7.6 kg). Anthropometric data was obtained using an iDXA scan. VO2max was determined using the diagonal stride technique on a ski treadmill. Bilateral functional tests for the upper and lower body were the handgrip and standing heel-rise tests. Vertical jump height and power were assessed with a counter movement jump...
December 2017: Journal of Human Kinetics
keyword
keyword
25504
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"