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https://www.readbyqxmd.com/read/28821180/infant-acceptance-of-primary-tastes-and-fat-emulsion-developmental-changes-and-links-with-maternal-and-infant-characteristics
#1
Camille Schwartz, Claire Chabanet, Emilie Szleper, Valérie Feyen, Sylvie Issanchou, Sophie Nicklaus
Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of each taste relative to water was defined using proportional variables that are based on ingestion (IR) or liking evaluated by the experimenter (LR). These data were analyzed with mixed models that accounted for age and subject effects (minimum 152 observations/age/taste; maximum 216)...
September 1, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28821120/enhanced-permeability-and-antifouling-performance-of-cellulose-acetate-ultrafiltration-membrane-assisted-by-l-dopa-functionalized-halloysite-nanotubes
#2
REVIEW
Keguang Mu, Dalun Zhang, Ziqiang Shao, Dujian Qin, Yalong Wang, Shuo Wang
l-Dopa functionalized halloysite nanotubes (HNTs) were prepared by the self-polymerization of l-dopa in the weak alkaline condition. Then different contents of l-dopa coated HNTs (LPDHNTs) were blended into cellulose acetate to prepare enhanced performance ultrafiltration membranes via the phase inversion method. The HNTs and LPDHNTs were characterized by FTIR, XPS, and TEM anysis. And the membranes morphologies, separation performance, antifouling performance, mechanical properties and hydrophilicity were also investigated...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821117/chitosan-based-thin-active-layer-membrane-for-forward-osmosis-desalination
#3
Alireza Shakeri, Hasan Salehi, Masoud Rastgar
A novel hydrophilic chitosan-based thin active layer membrane was elaborately fabricated through a facile method and its performance was studied in forward osmosis (FO) desalination process. Chitosan (CS) was interfacially polymerized with trimesoyl chloride (TMC) monomer on the surface of sulfonated polyethersulfone-polyethersulfone (SPES-PES) support layer. Two different procedures were employed to incorporate CS into the membrane thin active layer structure. The solutions containing different CS concentrations (from 0...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821094/decoration-of-open-pore-network-in-polyvinylidene-fluoride-mwcnts-with-chitosan-for-the-removal-of-reactive-orange-16-dye
#4
Maria Wasim, Sadia Sagar, Aneela Sabir, Muhammad Shafiq, Tahir Jamil
Inspired by the hydrophilic, biocompatible, adsorbent properties of chitosan. A simple, adaptable, green synthesis method was developed to prepare a thin film composite membranes using chitosan as a pore decorating material for the removal of anionic dye-Reactive orange 16 (RO-16). The hydrophilic chitosan was used to fill up the porous hydrophobic PVDF substrate, modified by MWCNTs. The dye rejection was carried out through the formation of a strong electrostatic interaction between the cationic group of chitosan surface and the anionic group of RO-16 dye...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820570/engineering-of-micro-to-nano-structured-3d-printed-drug-releasing-titanium-implants-for-enhanced-osseointegration-and-localized-delivery-of-anticancer-drugs
#5
Shaheer Maher, Gagandeep Kaur, Luis Lima-Marques, Andreas Evdokiou, Dusan Losic
Primary and secondary bone cancers are major causes of pathological bone fractures and their treatment through implant fixation and conventional chemotherapy has many limitations. These implants may suffer from poor osseointegration and their rejection is causing repeated surgery, patient's suffering and extensive expenses. On the other hand, there are severe systemic adverse effects of toxic chemotherapeutics administrated using conventional drug delivery. In this paper to address these two problems we present new type of localized drug-releasing titanium implants with enhanced implants' bio-integration and drug release capabilities that could provide high concentration of toxic anticancer drugs locally to treat bone cancers...
August 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28820045/effect-of-air-flow-rate-and-c-n-ratio-on-biological-nitrogen-removal-through-canon-process-treating-reject-water
#6
Seyyed Alireza Mousavi, Mohammad Mehralian, Maryam Khashij, Shaliza Ibrahim
CANON process is a promising way for nitrogen removal in wastewaters with low organic carbon content like reject water. This study investigated the effect of important factor for optimization of CANON process through inhibition of nitrite-oxidizing bacteria (NOB). In acclimation period, complete ammonium removal and 43.3% total N removal were obtained at HRT of 12 h, temperature of 30 ± 0.5 °C and DO equal to. The effect of air flow rate (representative of DO), SRT and C/N were evaluated. Air flow rate (AFR) was most important factor for controlling the process, but the effect of SRT was negligible...
August 18, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28819688/airway-reconstruction-using-decellularized-tracheal-allografts-in-a-porcine-model
#7
Michinobu Ohno, Yasushi Fuchimoto, Huai-Che Hsu, Masataka Higuchi, Makoto Komura, Tetsuji Yamaoka, Akihiro Umezawa, Shin Enosawa, Tatsuo Kuroda
PURPOSE: Tracheal cartilage reconstruction is an essential approach for the treatment of tracheal congenital abnormalities or injury. Here, we evaluated the use of allogeneic decellularized tracheas as novel support scaffolds. METHODS: Six weaned pigs (4-week-old domestic males) were transplanted with allogeneic tracheal graft patches (three decellularized and three fresh tracheal scaffolds) onto artificial defects (approximately 15 × 15 mm). After 11 weeks, the tracheas were evaluated by bronchoscopy and histological studies...
August 17, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28819637/cigarette-smoking-and-its-hazards-in-kidney-transplantation
#8
REVIEW
Muhammad Abdul Mabood Khalil, Jackson Tan, Said Khamis, Muhammad AshhadUllah Khalil, Rabeea Azmat, Arslan Rahat Ullah
Cigarette smoking affects many organs. It causes vasoconstriction through activation of sympathetic nervous system which leads to elevation of blood pressure and reduction in glomerular filtration rate and filtration pressure. It also causes thickening of renal arterioles. Cigarette smoking increases the risk of microalbuminuria and accelerates progression of microalbuminuria to macroalbuminuria. Furthermore, it causes rapid loss of glomerular filtration rate in chronic kidney disease patients. After kidney donation, these factors may be injurious to the solitary kidney...
2017: Advances in Medicine
https://www.readbyqxmd.com/read/28818787/socializing-girls-whose-bodies-may-not-align-with-contemporary-ideals-of-thinness-an-interpretive-study-of-us-mothers-accounts
#9
Jennifer Paff Ogle, Kelly Reddy-Best, Juyeon Park
We sought to understand how mothers of young adolescent girls who are perceived as overweight or at risk for becoming so and whose body mass indices are at the 70th percentile or higher socialize their daughters about body, weight, eating, and health. In-depth interviews were conducted with 13 US mothers, and data were analyzed using constant comparison processes. Findings revealed that mothers adopted a variety of strategies - including teaching, modeling, managing, avoiding, and comforting - to achieve varied socialization goals for their daughters...
August 14, 2017: Body Image
https://www.readbyqxmd.com/read/28818684/t-cell-mediated-rejection-of-human-cd34-cells-is-prevented-by-costimulatory-blockade-in-a-xenograft-model
#10
A L Oh, D Mahmud, B Nicolini, N Mahmud, V Senyuk, P R Patel, E Bonetti, M Arpinati, Jlm Ferrara, D Rondelli
A xenograft model of stem cell rejection was developed by co-transplantating human CD34+ and allogeneic CD3+ T cells into NOD-scid ɣ-chain(null) (NSG) mice. T cells caused graft failure when transplanted at any CD34:CD3 ratio between 1:50 to 1:0.1. Kinetics experiments showed that two weeks after transplantation CD34+ cells engrafted the marrow and T cells expanded in the spleen. Then at four weeks only memory T cells populated both sites and rejected CD34+ cells. Blockade of T cell costimulation was tested by injecting the mice with abatacept (CTLA4-IgG1) from day -1 to +27 (Group A), or from day -1 to +13 (Group B), or from day +14 to +28 (Group C)...
August 14, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28818632/the-views-of-clergy-regarding-ethical-controversies-in-care-at-the-end-of-life
#11
Michael J Balboni, Adam Sullivan, Patrick T Smith, Danish Zaidi, Christine Mitchell, James A Tulsky, Daniel Sulmasy, Tyler J VanderWeele, Tracy A Balboni
CONTEXT: While religion often informs ethical judgments, little is known about the views of American clergy regarding controversial end-of-life ethical issues including allowing to die and physician-aid in dying or physician-assisted suicide (PAD/PAS). OBJECTIVE: To describe the views of U.S. clergy concerning allowing to die and PAD/PAS. METHODS: A survey was mailed to 1665 nationally representative clergy between 8/2014 to 3/2015 (60% response rate)...
August 14, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28818615/deep-transcriptome-profiling-sheds-light-on-key-players-in-nucleus-implantation-induced-immune-response-in-the-pearl-oyster-pinctada-martensii
#12
Wei Wang, Yuyuan Wu, Qiannan Lei, Haiying Liang, Yuewen Deng
Immunological rejection of the pearl oysters following nucleus implantation is a major issue limiting the successful rate of cultured pearls. To date, the molecular mechanism of immune tolerance during pearl formation in the pearl oysters is still largely unknown. Through the RNA sequencing platform and comparative transcriptomic analysis, we investigated the chronic gene expression changes at seven time points (0, 5, 10, 15, 20, 30, 60 days post implantation or dpi) over a period of 60 days following nucleus implantation in the pearl oyster Pinctada martensii...
August 14, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28818581/renal-transplantation-in-systemic-lupus-erythematosus-comparison-of-graft-survival-with-other-causes-of-end-stage-renal-disease
#13
Gabriel Horta-Baas, Adolfo Camargo-Coronel, Dafhne Guadalupe Miranda-Hernández, Leslie Gabriela Gónzalez-Parra, María Del Socorro Romero-Figueroa, Mario Pérez-Cristóbal
INTRODUCTION: End-stage renal disease (ESRD) due to lupus nephritis (LN) occurs in 10%-30% of patients. Initially systemic lupus erythematosus (SLE) was a contraindication for kidney transplantation (KT). Today, long-term graft survival remains controversial. Our objective was to compare the survival after KT in patients with SLE or other causes of ESRD. METHODS: All SLE patients who had undergone KT in a retrospective cohort were included. Renal graft survival was compared with that of 50 controls, matched for age, sex, and year of transplantation...
August 14, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28818275/electromagnetic-fields-may-act-via-calcineurin-inhibition-to-suppress-immunity-thereby-increasing-risk-for-opportunistic-infection-conceivable-mechanisms-of-action
#14
P R Doyon, O Johansson
While a good number of studies have demonstrated that modern, man-made ambient electromagnetic fields can have both stimulatory and inhibitory effect on immune system function, the precise mechanisms have yet to be completely elucidated. It is hypothesized here that, depending on the parameters, one of the means by which long-term electromagnetic field exposure has the potential to eventually lead to immunosuppression is via downstream inhibition of the enzyme calcineurin - a protein phosphatase, which activates the T-cells of the immune system and can be blocked by pharmaceutical agents...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28817979/labor-market-position-after-a-rejection-of-a-disability-pension-application-a-register-based-cohort-study
#15
Mikko Laaksonen, Raija Gould, Jyri Liukko
PURPOSE: To study labor market positions of rejected disability pension applicants and to examine which characteristics predict ending up in these positions after the rejection. METHODS: Nationwide Finnish register data was used to describe employment, unemployment and disability pension trajectories of rejected applicants (n = 5740) from four years before to four years after the rejection. Demographic, occupational and health-related determinants of labor market position after the rejection were examined among those employed and not employed at the time of the rejection...
August 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28817400/liver-xenotransplantation
#16
Madhukar S Patel, Nathan Louras, Parsia A Vagefi
PURPOSE OF REVIEW: There continues to be an inadequate organ supply and lack of effective temporary support, for patients with liver failure. The purpose of this review is to discuss recent progress in the field of orthotopic pig-to-nonhuman primate (NHP) liver xenotransplantation (LXT). RECENT FINDINGS: From 1968 to 2012, survival in pig-to-NHP LXT was limited to 9 days, initially due to hyperacute rejection which has been ameliorated through use of genetically engineered donor organs, but ultimately because of profound thrombocytopenia, thrombotic microangiopathy, and bleeding...
August 16, 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28817391/tacrolimus-eye-drops-as-adjunct-therapy-in-severe-corneal-endothelial-rejection-refractory-to-corticosteroids
#17
Reza Ghaffari, Hamed Ghassemi, Mehran Zarei-Ghanavati, Golshan Latifi, Shima Dehghani, Zeeshan Haq, Ali R Djalilian
PURPOSE: To evaluate the safety and efficacy of tacrolimus eye drops as adjunctive therapy in the treatment of severe corneal endothelial rejection after penetrating keratoplasty refractory to corticosteroids. METHODS: In this prospective interventional case series, 11 eyes of 11 patients assessed for severe corneal endothelial rejection, with an inadequate response to topical, local, and systemic corticosteroids, were treated with either 0.01% or 0.05% tacrolimus eye drops 4 times daily...
August 16, 2017: Cornea
https://www.readbyqxmd.com/read/28816698/intralabyrinthine-vestibular-schwannoma-responsive-to-intratympanic-gentamicin-treatment
#18
Edoardo Covelli, Luigi Volpini, Chiara Filippi, Silvia Tarantini, Vania Marrone, Simonetta Monini, Maurizio Barbara
Intralabyrinthine schwannoma (ILS) is a rare benign tumor that affects the ends of cochlear and vestibular nerves. In a majority of the cases, it occurs with unilateral progressive sensorineural hearing loss. Less frequent symptoms include tinnitus, imbalance, vertigo, or fullness. The advent of magnetic resonance imaging allows early diagnosis and enables an appropriate therapeutic protocol. This report describes a case of intravestibular schwannoma, with fluctuating hearing loss and intractable vertigo, treated with intratympanic gentamicin...
August 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28816060/the-broad-spectrum-antimicrobial-potential-of-mn-co-4-s2cnme-ch2co2h-a-water-soluble-co-releasing-molecule-corm-401-intracellular-accumulation-transcriptomic-and-statistical-analyses-and-membrane-polarization
#19
Lauren Katie Wareham, Samantha McLean, Ronald Begg, Namrata Rana, Salar Ali, John J Kendall, Guido Sanguinetti, Brian E Mann, Robert K Poole
AIMS: Carbon monoxide (CO)-releasing molecules (CORMs) are candidates for animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a novel manganese CORM. RESULTS: [Mn(CO)4S2CNMe(CH2CO2H)], CORM-401, inhibits growth of Escherichia coli and several antibiotic-resistant clinical pathogens. CORM-401 releases CO that binds oxidases in vivo but is an ineffective respiratory inhibitor. Extensive CORM accumulation (assayed as intracellular manganese) accompanies antimicrobial activity...
August 17, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28815470/alterations-in-scai-expression-during-cell-plasticity-fibrosis-and-cancer
#20
Ákos Gasparics, Gábor Kökény, Attila Fintha, Rita Bencs, Miklós M Mózes, Emese Irma Ágoston, Anna Buday, Zoltán Ivics, Péter Hamar, Balázs Győrffy, László Rosivall, Attila Sebe
Suppressor of cancer cell invasion (SCAI) has been originally characterized as a tumor suppressor inhibiting metastasis in different human cancer cells, and it has been suggested that SCAI expression declines in tumors. The expression patterns and role of SCAI during physiological and pathophysiological processes is still poorly understood. Earlier we demonstrated that SCAI is regulating the epithelial-mesenchymal transition of proximal tubular epithelial cells, it is downregulated during renal fibrosis and it is overexpressed in Wilms' tumors...
August 16, 2017: Pathology Oncology Research: POR
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