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https://www.readbyqxmd.com/read/29785115/management-and-outcomes-of-pregnancy-with-or-without-lupus-nephritis-a-systematic-review-and-meta-analysis
#1
REVIEW
Jiayue Wu, Jinghang Ma, Wei-Hong Zhang, Wen Di
Background: Although it is well established that systemic lupus erythematosus (SLE) negatively affects pregnancy outcomes, there is insufficient evidence on the effect of lupus nephritis (LN) on antenatal management and pregnancy outcomes. We performed a systematic review and meta-analysis to determine the association of LN with management and pregnancy outcomes in SLE patients. Methods: Embase, Medline, Cochrane, and ClinicalTrials.gov were carefully searched for relevant English and Chinese language studies...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29760513/author-correction-fetal-cardiac-cine-magnetic-resonance-imaging-in-utero
#2
Jerome Chaptinel, Jerome Yerly, Yvan Mivelaz, Milan Prsa, Leonor Alamo, Yvan Vial, Gregoire Berchier, Chantal Rohner, François Gudinchet, Matthias Stuber
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29743807/self-medication-practice-and-associated-factors-among-pregnant-women-in-addis-ababa-ethiopia
#3
Kidanemariam G/Michael Beyene, Solomon Worku Beza
Background: Self-medication which is the act of obtaining and using one or more medicines without medical supervision is a common practice among pregnant women. Unless proper caution is taken, it may result in maternal and fetal adverse outcomes. In Ethiopia, information on self-medication practice during pregnancy is scanty. Hence, this study aimed to assess self-medication practice and associated factors among pregnant women in government health centers in Addis Ababa. Methods: An institution-based mixed study design using a sequential explanatory approach was employed among 617 pregnant women and nine key informants in Addis Ababa from May 8, 2017, to June 30, 2017...
2018: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29733091/mesenchymal-stem-cells-from-the-perivascular-environment-to-clinical-applications
#4
REVIEW
Bianca Vezzani, Enrico Pierantozzi, Vincenzo Sorrentino
Adult stem cells represent a fundamental biological system that has fascinated scientists over the last decades, and are currently the subject of a large number of studies aimed at better defining the properties of these cells, with a prominent focus on improving their application in regenerative medicine. One of the most used adult stem cells in clinical trials are mesenchymal stem cells (MSCs), which are multipotent cells able to differentiate into mature cells of mesodermal lineages. Following the initial studies on MSCs isolated from bone marrow, similar cells were also isolated from a variety of fetal and adult human tissues...
May 7, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29717296/profile-of-caesarean-section-in-mid-western-regional-hospital-in-nepal
#5
Keshar Bahadur Dhakal, Sulochana Dhakal, Saroj Bhandari
BACKGROUND: Rising rate of caesarean section since few decades has been a global public health issue.This study is aimed to determine the rate of caesarean section plus examine the indications and complications of caesarean section. METHODS: A retrospective cross-sectional study was conducted using secondary data sources at Mid-Western Regional Hospital in Surkhet, Nepal. Data were collected from patients'records ofthe hospital dating from 16 July 2016 to 15 July 2017...
March 13, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29714717/dosimetric-factors-for-diagnostic-nuclear-medicine-procedures-in-a-non-reference-pregnant-phantom
#6
Laleh Rafat-Motavalli, Hashem Miri Hakimabad, Elie Hoseinian Azghadi
This study was evaluated the impact of using non-reference fetal models on the fetal radiation dose from diagnostic radionuclide administration. The 6 month pregnant phantoms including fetal models at 10th and 90th growth percentiles were constructed at either end of the normal range around the 50th percentile and implemented in the Monte Carlo N-Particle code version MCNPX 2.6. The code have been used then to evaluate the 99mTc S factors of interested target organs as the most common used radionuclide in nuclear medicine procedures...
May 1, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29707695/serum-heat-shock-protein-70-in-preeclampsia-and-normal-pregnancy-a-systematic-review-and-meta-analysis
#7
REVIEW
Nafiseh Saghafi, Leila Pourali, Vahid Ghavami Ghanbarabadi, Fatemeh Mirzamarjani, Masoumeh Mirteimouri
Background: Preeclampsia, a severe complication of human pregnancy is one of the main causes of maternal, fetal, and neonatal morbidity and mortality with unclear pathogenesis. Heat shock protein 70 (HSP70) is one of the factors that can mediate cytoprotective, antiapoptotic, and immune regulatory effects. Objective: This meta-analysis was performed with aim to evaluate HSP70 in preeclampsia and normal pregnancy. Materials and Methods: The original publications reporting the serum HSP70 levels in preeclampsia and normal pregnancies published before November 2015 were identified by searching PubMed Central, Scopus, and ISI Web of Knowledge databases by two researchers, separately...
January 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29661182/women-s-perspectives-on-the-ethical-implications-of-non-invasive-prenatal-testing-a-qualitative-analysis-to-inform-health-policy-decisions
#8
Meredith Vanstone, Alexandra Cernat, Jeff Nisker, Lisa Schwartz
BACKGROUND: Non-Invasive Prenatal Testing (NIPT) is a technology which provides information about fetal genetic characteristics (including sex) very early in pregnancy by examining fetal DNA obtained from a sample of maternal blood. NIPT is a morally complex technology that has advanced quickly to market with a strong push from industry developers, leaving many areas of uncertainty still to be resolved, and creating a strong need for health policy that reflects women's social and ethical values...
April 16, 2018: BMC Medical Ethics
https://www.readbyqxmd.com/read/29659791/human-placental-growth-hormone-variant-in-pathological-pregnancies
#9
Shutan Liao, Mark H Vickers, Joanna L Stanley, Philip N Baker, Jo K Perry
Growth hormone (GH), an endocrine hormone primarily secreted from the anterior pituitary, stimulates growth, cell reproduction and regeneration and is a major regulator of postnatal growth. Humans have two GH genes which encode two versions of GH proteins: a pituitary version (GH-N/GH1), and a placental GH variant (GH-V/GH2) which is expressed in the syncytiotrophoblast and extravillous trophoblast cells of the placenta. During pregnancy, placental GH replaces pituitary GH in the maternal circulation at mid-late gestation as the major circulating form of GH...
April 6, 2018: Endocrinology
https://www.readbyqxmd.com/read/29627817/quantitative-fibronectin-to-help-decision-making-in-women-with-symptoms-of-preterm-labour-quids-part-1-individual-participant-data-meta-analysis-and-health-economic-analysis
#10
Sarah J Stock, Lisa M Wotherspoon, Kathleen A Boyd, Rachel K Morris, Jon Dorling, Lesley Jackson, Manju Chandiramani, Anna L David, Asma Khalil, Andrew Shennan, Victoria Hodgetts Morton, Tina Lavender, Khalid Khan, Susan Harper-Clarke, Ben W Mol, Richard D Riley, John Norrie, Jane E Norman
INTRODUCTION: The aim of the QUIDS study is to develop a decision support tool for the management of women with symptoms and signs of preterm labour, based on a validated prognostic model using quantitative fetal fibronectin (qfFN) concentration, in combination with clinical risk factors. METHODS AND ANALYSIS: The study will evaluate the Rapid fFN 10Q System (Hologic, Marlborough, Massachusetts) which quantifies fFN in a vaginal swab. In part 1 of the study, we will develop and internally validate a prognostic model using an individual participant data (IPD) meta-analysis of existing studies containing women with symptoms of preterm labour alongside fFN measurements and pregnancy outcome...
April 7, 2018: BMJ Open
https://www.readbyqxmd.com/read/29572823/a-systematic-review-and-meta-analysis-of-velamentous-cord-insertion-among-singleton-pregnancies-and-the-risk-of-preterm-delivery
#11
REVIEW
Samantha de Los Reyes, Janice Henderson, Ahizechukwu C Eke
BACKGROUND: Observational studies have reported varying results about the association of velamentous cord insertion (VCI) with adverse pregnancy outcomes. OBJECTIVES: To evaluate the risk of preterm delivery among singleton pregnancies complicated by VCI. SEARCH STRATEGY: Various databases were searched for English-language articles published up to February, 28, 2017, using keywords including VCI; abnormal placentation; abnormal cord insertions; adverse perinatal outcomes; and preterm birth...
March 23, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29564255/prospective-study-on-prevalence-of-anemia-of-pregnant-women-and-its-outcome-a-community-based-study
#12
Ravishankar Suryanarayana, Muninarayana Chandrappa, Anil Navale Santhuram, S Prathima, S R Sheela
Background: Anemia is one of the most common nutritional deficiency disorders affecting the pregnant women in the developing countries. Anemia during pregnancy is commonly associated with poor pregnancy outcome and can result in complications that threaten the life of both mother and fetus. Objective: The objective of the study was to estimate the prevalence of anemia among pregnant women and to determine its association with maternal and fetal outcomes. Settings and Design: This study design was a prospective, observational, community-based study...
October 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29560164/comparison-of-umbilical-artery-doppler-and-non-stress-test-in-assessment-of-fetal-well-being-in-gestational-diabetes-mellitus-a-prospective-cohort-study
#13
Shirin Niromanesh, Mahboobeh Shirazi, Mitra Eftekhariyazdi, Forough Mortazavi
Background: Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy and is related to poor perinatal outcomes. Reduction of neonatal complications of GDM is feasible by assessment of fetal well-being. Both fetal Doppler and NST are used for the screening of high-risk pregnancies. Objective: We aimed to compare the non-stress test (NST) and umbilical artery (UA) Doppler assessments for evaluation of the adverse perinatal outcomes in GDM...
December 2017: Electronic Physician
https://www.readbyqxmd.com/read/29560141/maternal-fetal-rhesus-rh-factor-incompatibility-in-arar-northern-saudi-arabia
#14
Raghad Mubarak Aljuhaysh, Nagah Mohamed Abo El-Fetoh, Malak Ibrahim Alanazi, Afaf Shuaib Albaqawi, Wafa Mohammed Alanazi, Najah Salah Alanazi, Reham Muqbil Alanazi, Atheer Mutab Alanazi, Eiman Mohammad Alnemer, Rahma Abdulhadi Alenezi, Tasleem Khoudier Alabdullatif, Rehab Abdallah Alanazi, Samiyah Sarhan Alanazi, Kawthar Saeed Alsultan, Ibtisam Matan Alanazi, Duaa Sami Alsunayni
Background and aim: Rh isoimmunization still contributes to the neonatal morbidity and mortality due to non-immunization, under-immunization, and in rare cases, false Rh typing. The main objective of this study was to determine the prevalence of Rh incompatibility, mothers' knowledge about Rh incompatibility, mothers' knowledge about anti-D immunoglobulin and to show the pregnancy outcome of Rh negative mothers. Methods: A cross-sectional study was carried out at the Maternity and Children Hospital in Arar city from November 2016 to May 2017...
December 2017: Electronic Physician
https://www.readbyqxmd.com/read/29551660/fetal-alcohol-spectrum-disorders-fasd-what-we-know-and-what-we-should-know-the-knowledge-of-german-health-professionals-and-parents
#15
Mirjam N Landgraf, Lucia Albers, Birte Rahmsdorf, Katharina Vill, Lucia Gerstl, Michaela Lippert, Florian Heinen
OBJECTIVE: The objective of our study was to evaluate the knowledge about fetal alcohol spectrum disorders (FASD) and the implementation of the German guideline for FASD among different professionals in the health and social system and among parents with children with FASD. METHODS: A questionnaire about FASD, containing 20 items, was sent by post to all children's hospitals (n = 287), all hospitals for child and adolescent psychiatry (n = 173), all social paediatric centres (n = 162), all neuropaediatricians (n = 129) and all youth welfare offices (n = 672) in Germany...
May 2018: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29517386/prenatal-attachment-inventory-expanding-the-reliability-and-validity-evidence-using-a-sample-of-italian-women
#16
Alessandra Busonera, Stefania Cataudella, Jessica Lampis, Marco Tommasi, Giulio Cesare Zavattini
BACKGROUND: The Prenatal Attachment Inventory (PAI) is a widely used questionnaire to measure prenatal attachment. However, its internal structure is controversial. None of the previous studies have investigated the dimensions of the Italian version of the scale using both an exploratory and a confirmatory approach. There is also a need to explore extensively the external validity of the Italian PAI. OBJECTIVE: We designed a study aimed at shedding further light on the dimensionality of the questionnaire and expanding the evidence of its reliability and validity...
November 2017: Journal of Reproductive and Infant Psychology
https://www.readbyqxmd.com/read/29517298/maternal-attachment-style-during-pregnancy-and-becoming-a-mother-in-poland
#17
Anna Zdolska-Wawrzkiewicz, Magdalena Chrzan-Dętkoś, Mariola Bidzan
OBJECTIVE: This paper investigates the connections in pregnant women between their mother attachment style and their self-image as a mother, the image of their mother as a mother, and their bond with the unborn child. BACKGROUND: The relationship with one's mother plays a crucial role in the process of becoming a mother. It influences what a pregnant woman thinks about herself as a mother. This relationship is a predictor of the bond with the child during the pregnancy...
February 2018: Journal of Reproductive and Infant Psychology
https://www.readbyqxmd.com/read/29491625/zerumbone-suppresses-angiogenesis-in-hepg2-cells-through-inhibition-of-matrix-metalloproteinase-9-vascular-endothelial-growth-factor-and-vascular-endothelial-growth-factor-receptor-expressions
#18
Nozlena Abdul Samad, Ahmad Bustamam Abdul, Heshu Sulaiman Rahman, Abdullah Rasedee, Tengku Azmi Tengku Ibrahim, Yeap Swee Keon
Context: Due to increase in the number of patients with impaired immunity, the incidence of liver cancer has increased considerably. Aims: The aim of this study is the investigation the in vitro anticancer effect of zerumbone (ZER) on hepatocellular carcinoma (HCC). Materials and Methods: The anticancer mechanism of ZER was determined by the rat aortic ring, human umbilical vein endothelial cells (HUVECs) proliferation, chorioallantoic membrane, cell migration, and proliferation inhibition assays...
January 2018: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29479676/experiences-of-living-with-fetal-alcohol-spectrum-disorders-a-systematic-review-and-synthesis-of-qualitative-data
#19
REVIEW
Helena Domeij, Gunilla Fahlström, Göran Bertilsson, Monica Hultcrantz, Heather Munthe-Kaas, Christina Nehlin Gordh, Gert Helgesson
AIM: To identify and assess available evidence from qualitative studies exploring experiences of individuals living with fetal alcohol spectrum disorders (FASD) or those living with a child with FASD, as well as experiences of interventions aimed at supporting individuals with FASD and their families. METHOD: A systematic literature search was conducted in six electronic databases: PubMed, Embase, Cochrane Library, CINAHL, PsycINFO, and Scopus. Included studies were analysed using manifest content analysis...
February 26, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29474437/validation-of-a-snp-based-non-invasive-prenatal-test-to-detect-the-fetal-22q11-2-deletion-in-maternal-plasma-samples
#20
Harini Ravi, Gabriel McNeill, Shruti Goel, Steven D Meltzer, Nathan Hunkapiller, Allison Ryan, Brynn Levy, Zachary P Demko
INTRODUCTION: Non-invasive prenatal testing (NIPT) for aneuploidy using cell-free DNA in maternal plasma has been widely adopted. Recently, NIPT coverage has expanded to detect subchromosomal abnormalities including the 22q11.2 deletion. Validation of a SNP-based NIPT for detection of 22q11.2 deletions demonstrating a high sensitivity (97.8%) and specificity (99.75%) has been reported. We sought to further demonstrate the performance of a revised version of the test in a larger set of pregnancy plasma samples...
2018: PloS One
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