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https://www.readbyqxmd.com/read/28299299/effect-of-early-physical-activity-programs-on-motor-performance-and-neuromuscular-development-in-infants-born-preterm-a-randomized-clinical-trial
#1
Leila Valizadeh, Mahnaz Sanaeefar, Mohammad Bager Hosseini, Mohammad Asgari Jafarabadi, Aryan Shamili
Introduction: Although the survival rate of infants born preterm has increased, the prevalence of developmental problems and motor disorders among this population of infants remains the same. This study investigated the effect of physical activity programs in and out of water on motor performance and neuromuscular development of infants born preterm and had induced immobility by mechanical ventilation. Methods: This study was carried out in Al-Zahra hospital, Tabriz. 76 premature infants were randomly assigned into four groups...
March 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/28270583/a-reverse-genetics-platform-that-spans-the-zika-virus-family-tree
#2
Douglas G Widman, Ellen Young, Boyd L Yount, Kenneth S Plante, Emily N Gallichotte, Derek L Carbaugh, Kayla M Peck, Jessica Plante, Jesica Swanstrom, Mark T Heise, Helen M Lazear, Ralph S Baric
Zika virus (ZIKV), a mosquito-borne flavivirus discovered in 1947, has only recently caused large outbreaks and emerged as a significant human pathogen. In 2015, ZIKV was detected in Brazil, and the resulting epidemic has spread throughout the Western Hemisphere. Severe complications from ZIKV infection include neurological disorders such as Guillain-Barré syndrome in adults and a variety of fetal abnormalities, including microcephaly, blindness, placental insufficiency, and fetal demise. There is an urgent need for tools and reagents to study the pathogenesis of epidemic ZIKV and for testing vaccines and antivirals...
March 7, 2017: MBio
https://www.readbyqxmd.com/read/28255521/management-of-breast-cancer-during-pregnancy-are-we-compliant-with-current-guidelines
#3
Victoria Shlensky, Sigrun Hallmeyer, Lourdes Juarez, Barbara V Parilla
Introduction The purpose of this study was to evaluate the management of patients with breast cancer in pregnancy treated at the Advocate Health Care, to determine whether these patients were treated according to guidelines for pregnant patients, which aim to maximize both fetal and maternal outcomes. Methods A retrospective chart review was performed at the Advocate Lutheran General Hospital, Christ Medical Center, and Illinois Masonic Medical Center from 2002 to 2012 on patients diagnosed with breast cancer during pregnancy using ICD-9 (International Classification of Diseases - 9th version) codes...
January 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28230268/potential-climate-change-health-risks-from-increases-in-heat-waves-abnormal-birth-outcomes-and-adverse-maternal-health-conditions
#4
Gulcan Cil, Trudy Ann Cameron
We investigate the risks presented by heat waves for adverse health conditions for babies and expectant mothers when these mothers have been exposed to heat waves during gestation or during the period just prior to conception. Rather than just birth weight and gestational age, we focus on less common metrics such as abnormal conditions in the newborn (fetal distress, reliance on a ventilator, and meconium aspiration) and adverse health conditions in the mother (pregnancy-related hypertension, uterine bleeding during pregnancy, eclampsia, and incompetent cervix)...
February 23, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28208963/clinical-profile-of-cardiac-arrhythmias-in-children-attending-the-out-patient-department-of-a-tertiary-paediatric-care-centre-in-chennai
#5
Sarala Premkumar, Premkumar Sundararajan, Thangavelu Sangaralingam
INTRODUCTION: The presentation of symptoms of paediatric arrhythmias vary depending on the age and underlying heart disease. Physical examination of children with important arrhythmias may be entirely normal. AIM: Aim is to study the characteristics of cardiac arrhythmias in paediatric patients in a tertiary paediatric care centre in Chennai, India. MATERIALS AND METHODS: The participants (n=60) were from birth to 12 years of age. Patients with sinus arrhythmias, sinus tachycardia and sinus bradycardia were excluded...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28176187/brucellosis-and-associated-risk-factors-in-dairy-cattle-of-eastern-ethiopia
#6
Yitagele Terefe, Sisay Girma, Negesse Mekonnen, Biruhtesfa Asrade
Knowing the status of Bovine brucellosis and associated risk factors is a crucial step in formulating evidence based control scheme. In this study, a total of 967 dairy cows from 307 dairy farms in eastern Ethiopia were serologically tested for Brucella antibodies. The screening was done first using RBPT and positive samples were subsequently subjected to CFT for confirmation. A pre-tested structured questionnaire was used to collect relevant data from 307 dairy cattle owners or attendants to assess their awareness and routine practice...
March 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28131122/obstetric-and-anesthetic-approaches-to-external-cephalic-version
#7
REVIEW
Stephanie Lim, Jennifer Lucero
Breech presentation is the most common abnormal fetal presentation and complicates approximately 3% to 4% of all pregnancies. External cephalic version (ECV) should be recommended to women with a breech singleton pregnancy, if there is no maternal or fetal contraindication. ECV increases the chance of cephalic presentation at the onset of labor and decreases the rate of cesarean delivery by almost 40%. The success rate of ECV is approximately 60%. Review of the risks and benefits for performing an ECV and for both the timing of ECV and the number of attempts should be should be discussed with the patient...
March 2017: Anesthesiology Clinics
https://www.readbyqxmd.com/read/28126898/atosiban-versus-fenoterol-as-a-uterine-relaxant-for-external-cephalic-version-randomised-controlled-trial
#8
Joost Velzel, Floortje Vlemmix, Brent C Opmeer, Jan F M Molkenboer, Corine J Verhoeven, Mariëlle G van Pampus, Dimitri N M Papatsonis, Joke M J Bais, Karlijn C Vollebregt, Liesbeth van der Esch, Joris A M Van der Post, Ben Willem Mol, Marjolein Kok
OBJECTIVE:  To compare the effectiveness of the oxytocin receptor antagonist atosiban with the beta mimetic fenoterol as uterine relaxants in women undergoing external cephalic version (ECV) for breech presentation. DESIGN:  Multicentre, open label, randomised controlled trial. SETTING:  Eight hospitals in the Netherlands, August 2009 to May 2014. PARTICIPANTS:  830 women with a singleton fetus in breech presentation and a gestational age of more than 34 weeks were randomly allocated in a 1:1 ratio to either 6...
January 26, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28125970/the-use-of-the-mhealth-program-smarter-pregnancy-in-preconception-care-rationale-study-design-and-data-collection-of-a-randomized-controlled-trial
#9
Matthijs R van Dijk, Elsje C Oostingh, Maria P H Koster, Sten P Willemsen, Joop S E Laven, Régine P M Steegers-Theunissen
BACKGROUND: Unhealthy nutrition and lifestyle contribute to the worldwide rising prevalence of non-communicable diseases. This also accounts for the reproductive population, in which unhealthy behavior affects fertility and pregnancy outcome. Maternal smoking, alcohol consumption and inadequate folic acid supplement use are strongly associated with fetal complications as small for gestational age, premature birth and congenital malformations. In the Netherlands 83% of the perinatal mortality rate is due to these complications and is relatively high compared to other European countries...
January 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28056690/2017-guidelines-of-the-american-thyroid-association-for-the-diagnosis-and-management-of-thyroid-disease-during-pregnancy-and-the-postpartum
#10
Erik K Alexander, Elizabeth N Pearce, Gregory A Brent, Rosalind S Brown, Herbert Chen, Chrysoula Dosiou, William A Grobman, Peter Laurberg, John H Lazarus, Susan J Mandel, Robin P Peeters, Scott Sullivan
BACKGROUND: Thyroid disease in pregnancy is a common clinical problem. Since the guidelines for the management of these disorders by the American Thyroid Association (ATA) were first published in 2011, significant clinical and scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid disease in women during pregnancy, preconception, and the postpartum period...
March 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27991726/an-optimised-version-of-the-secretome-protein-enrichment-with-click-sugars-specs-method-leads-to-enhanced-coverage-of-the-secretome
#11
Alperen Serdaroglu, Stephan A Müller, Ute Schepers, Stefan Bräse, Wilko Weichert, Stefan F Lichtenthaler, Peer-Hendrik Kuhn
The secretome, the entirety of all soluble proteins either being secreted or proteolytically released by a cell, plays a key role in inter-cellular communication of multi-cellular organisms. Pathological alterations contribute to diseases such as hypertension, cancer, autoimmune disorders or neurodegenerative diseases. Hence, studying disease-related perturbations of the secretome and the secretome itself covers an important aspect of cellular physiology. We recently developed the secretome protein enrichment with click sugars (SPECS) method that enables the analysis of secretomes of in vitro cell cultures even in the presence of FCS with MS...
December 19, 2016: Proteomics
https://www.readbyqxmd.com/read/27988357/recombinant-alpha-1-microglobulin-a-potential-treatment-for-preeclampsia
#12
REVIEW
Rolf Gunnarsson, Bo Åkerström, Stefan R Hansson, Magnus Gram
Preeclampsia is a serious pregnancy-specific condition, affecting 10 million women annually worldwide. No specific treatment is currently available. Recent studies have demonstrated abnormal production and accumulation of free fetal hemoglobin in the preeclamptic placenta, and identified subsequent leakage into the maternal circulation as an important factor in the development of preeclampsia. A recombinant version of alpha-1-microglobulin, an endogenous well-characterized heme and radical scavenger, has been developed...
December 14, 2016: Drug Discovery Today
https://www.readbyqxmd.com/read/27966224/the-development-of-a-culturally-appropriate-school-based-intervention-for-australian-aboriginal-children-living-in-remote-communities-a-formative-evaluation-of-the-alert-program-%C3%A2-intervention
#13
Bree Wagner, James Fitzpatrick, Martyn Symons, Tracy Jirikowic, Donna Cross, Jane Latimer
BACKGROUND/AIM: Although previous research has demonstrated the benefits of targeting self-regulation in non-Aboriginal children, it is unclear whether such programs would be effective for Aboriginal children attending school in remote communities. Some of these children have been diagnosed with a fetal alcohol spectrum disorder (FASD) impairing their ability to self-regulate. The aim of this article is to describe a three phase formative process to develop and pilot a curriculum version of the Alert Program(®) , a promising intervention for improving self-regulation that could be used in remote community schools...
December 13, 2016: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/27939488/first-and-second-trimester-immune-biomarkers-in-preeclamptic-and-normotensive-women
#14
Brandie D Taylor, Roberta B Ness, Mark A Klebanoff, Roger Zoh, Debra Bass, David M Hougaard, Kristin Skogstrand, Catherine L Haggerty
INTRODUCTION: Circulating immune markers may be associated with preeclampsia but further investigations in early pregnancy and among preeclampsia subtypes are warranted. We examined immune markers in 208 preeclamptic women and 411 normotensive controls. METHODS: Our study was nested within the Collaborative Perinatal Project. A total of 242 women had first trimester serum samples and 392 had second trimester serum samples. Preeclampsia was defined as hypertension >20weeks of gestation with proteinuria or pulmonary edema, oliguria, or convulsions...
October 2016: Pregnancy Hypertension
https://www.readbyqxmd.com/read/27925227/an-erp-study-of-response-inhibition-in-the-auditory-domain-in-children-with-fetal-alcohol-spectrum-disorders
#15
Matthew M Gerhold, Sandra W Jacobson, Joseph L Jacobson, Christopher D Molteno, Ernesta M Meintjes, Colin M Andrew
BACKGROUND: Previous event-related potential (ERP) studies of response inhibition in children with fetal alcohol spectrum disorder (FASD) have used a visual Go/NoGo task to study the impact of prenatal alcohol exposure on response inhibition. No studies exist using auditory versions of the task; thus, it is unclear how the deficits observed in visual tasks translate into the auditory domain. METHODS: This study examined ERPs using an auditory Go/NoGo paradigm in a sample of 35 school-age children-18 with heavy prenatal alcohol exposure and 17 normally developing controls...
January 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27912030/perinatal-outcomes-and-the-influence-of-maternal-characteristics-after-roux-en-y-gastric-bypass-surgery
#16
Cristiane Chagas, Cláudia Saunders, Silvia Pereira, Jacqueline Silva, Carlos Saboya, Andréa Ramalho
OBJECTIVE: Assess the perinatal outcomes and identify what maternal characteristics can influence them in women who had undergone Roux-en-Y gastric bypass (RYGB). MATERIALS AND METHODS: Analytical, prospective, and longitudinal study with pregnant adult women. INCLUSION CRITERIA: chronological age >20 years; singleton pregnancy; RYGB surgery before pregnancy. EXCLUSION CRITERIA: prior malabsorptive or restrictive surgeries; malabsorption syndrome...
January 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/27888119/prenatal-phthalate-triclosan-and-bisphenol-a-exposures-and-child-visual-spatial-abilities
#17
Joseph M Braun, David C Bellinger, Russ Hauser, Robert O Wright, Aimin Chen, Antonia M Calafat, Kimberly Yolton, Bruce P Lanphear
INTRODUCTION: During fetal development, sex steroids influence sexually dimorphic behaviors, such as visual-spatial abilities. Thus, endocrine disrupting chemicals that impact sex steroids during gestation may affect these behaviors. OBJECTIVE: We investigated the relationship between prenatal urinary phthalate metabolite, triclosan, and BPA concentrations and visual-spatial abilities in a prospective cohort of 198 mother-child dyads. METHODS: Data are from a prospective cohort in Cincinnati, OH (HOME Study)...
January 2017: Neurotoxicology
https://www.readbyqxmd.com/read/27863606/use-of-complementary-and-alternative-medicine-in-pregnancy-and-its-impact-on-obstetric-outcome
#18
Juliana Yusof, Zaleha Abdullah Mahdy, Rushdan Mohd Noor
OBJECTIVE: To evaluate the prevalence of use of complementary and alternative medicine (CAM) in a Malaysian antenatal population and its impact on obstetric outcome. DESIGN: Cross sectional study. SETTING: Obstetric Unit, Hospital Sultanah Bahiyah, Alor Setar, Kedah. MATERIAL AND METHOD: Women attending antenatal clinic and Patient Admission Centre (PAC) above 30 weeks gestation were given structured questionnaires to fill...
November 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27853333/gallic-acid-inhibits-proliferation-and-induces-apoptosis-in-lymphoblastic-leukemia-cell-line-c121
#19
Zahra Sourani, Batoul Pourgheysari, Pezhman Beshkar, Hedayatollah Shirzad, Moein Shirzad
Leukemia is known as the world's fifth most prevalent cancer. New cytotoxic drugs have created considerable progress in the treatment, but side effects are still the important cause of mortality. Plant derivatives have been recently considered as important sources for the treatment of various diseases, including cancer. Gallic acid (GA) is a polyhydroxyphenolic compound with a wide range of biological functions. The aim of the present study was to evaluate the effect of GA on proliferation inhibition and apoptosis induction of a lymphoblastic leukemia cell line...
November 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27830875/oblique-cord-chorda-obliqua-of-the-forearm-and-muscle-associated-fibrous-tissues-at-and-around-the-elbow-joint-a-study-of-human-foetal-specimens
#20
Z W Jin, Y Jin, M Yamamoto, H Abe, G Murakami, T F Yan
In adults, the oblique cord or chorda obliqua separates the origins of the flexor pollicis longus (FPL) and flexor digitorum profundus (FDP) muscles from the supinator muscle and elbow joint. This study examined the topographic anatomy of the oblique cord and related muscles in foetuses. Semiserial sections of five mid-term foetuses of gestational age (GA) 14-16 weeks and 12 late-stage foetuses of GA 28-30 weeks were histologically examined and three forearms at GA 30 weeks were macroscopically evaluated. Late-stage foetuses showed a fascial structure between the supinator and FDP muscles...
2016: Folia Morphologica (Warsz)
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