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Flavia Westphal, Suzete Maria Fustinoni, Vânia Lopes Pinto, Patrícia de Souza Melo, Anelise Riedel Abrahão
Objective: To identify the profile of women seen in a Fetal Medicine unit, diagnosed with fetal abnormality incompatible with neonatal survival in their current pregnancy, and to check the association of gestational age upon diagnosis with the option of pregnancy termination. Methods: This is a retrospective cohort study carried out in the Fetal Medicine Outpatients Clinic of a university hospital, in the city of São Paulo (SP), Brazil, using medical records of pregnant women with fetus presenting abnormalities incompatible with neonatal survival...
July 2016: Einstein
Mohsen Rashidi, Seyed Ali Ziai, Taraneh Moini Zanjani, Ahad Khalilnezhad, Hamidreza Jamshidi, Davar Amani
BACKGROUND: Resistance to chemotherapy is a growing concern, thus natural anticancer agents are drawing the attention of many scientists and clinicians. One natural anticancer agent, umbelliprenin, is a coumarin produced by many species of Ferula. OBJECTIVES: We aimed to examine the inhibitory effect of umbelliprenin on human and mouse bone marrow-derived stem cells (BMDSCs), peripheral blood mononuclear cells (PBMCs), and different cancer cell lines. MATERIALS AND METHODS: In this in vitro experimental study, the HT29, CT26, MCF-7, 4T1, A172, and GL26 cancer cells and human and mouse BMDSCs and PBMCs were cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum (FBS), incubated at 37°C for 24 hours in a 5% CO2 atmosphere, and then were treated with different concentrations of umbelliprenin dissolved in dimethyl sulfoxide (DMSO) (3, 6, 12, 25, 50, 100, and 200 µg/mL) for 24, 48, and 72 hours at 37°C...
July 2016: Iranian Red Crescent Medical Journal
E Merz, C Thode, B Eiben, S Wellek
AIM: Both previous versions of the German PRC algorithm developed by our group for routine first-trimester screening relied on the assumption that maternal blood sampling and fetal ultrasonography are performed at the same visit of a pregnant women. In this paper we present an extension of our method allowing also for constellations where this synchronization is abandoned through preponing blood sampling to dates before 11 weeks of gestation. METHODS: In contrast to the directly measured concentrations of the serum parameters PAPP-A and free ß-hCG, the logarithmically transformed values could be shown to admit the construction of reference bands covering the whole range from 16 to 84 mm CRL [corresponding to 63 to 98 days of gestation]...
March 2016: Ultrasound Int Open
Gisele Ferreira Paris, Francine de Montigny, Sandra Marisa Pelloso
OBJECTIVE: To verify the association between complicated grief and sociodemographic, reproductive, mental, marital satisfaction, and professional support characteristics in women after stillbirth. METHOD: Cross-sectional study with 26 women who had stillbirth in 2013, living in the city of Maringá, Brazil, and eight women who attended the Centre d'Études et de Rechercheen Intervention Familiale at the University of Quebec en Outaouais, in Canada. The instrument was administered as an interview to a small number of mothers of infants up to three months (n=50), who did not participate in the validation study...
July 2016: Revista da Escola de Enfermagem da U S P
Maryam Sadat Maddahi, Mahrokh Dolatian, Monirsadat Khoramabadi, Atefeh Talebi
INTRODUCTION: Low birth weight due to preterm delivery or intrauterine growth restriction (IUGR) is the strongest factor contributing to prenatal, neonatal, and postnatal mortality. Maternal-fetal attachment plays a significant role in maternal and fetal health. Health practices performed by the mother during pregnancy constitute one of the factors that may affect neonatal outcomes. The present study was conducted to identify the relationship between maternal-fetal attachment and health practices during pregnancy with neonatal outcomes...
July 2016: Electronic Physician
Nancy S Green, Deepa Manwani, Mahvish Qureshi, Karen Ireland, Arpan Sinha, Arlene M Smaldone
BACKGROUND: Hydroxyurea (HU) induces dose-dependent increased fetal hemoglobin (HbF) for sickle cell disease (SCD). Large deviation from historical personal best (PBest) HbF, a clinic-based version of maximum dose, may identify a subset with suboptimal HU adherence over time. PROCEDURE: Retrospective clinical data from youth ages 10-18 years prescribed HU at two centers were extracted from medical records at three time points: pre-HU initiation, PBest and a recent assessment...
August 30, 2016: Pediatric Blood & Cancer
Zubaida Garba Abdullahi, Mohammmed A Abdul, Sirajo M Aminu, Bolanle O P Musa, Lawal Amadu, El-Bashir M Jibril
CONTEXT: The association between antiphospholipid antibodies (APAs) and pregnancy loss has been established and now considered as a treatable cause of pregnancy loss. Data on the prevalence of APA in patients with recurrent pregnancy loss are scarce in our environment. AIMS: To determine the prevalence of APA in pregnant women with and without recurrent fetal wastage. SETTINGS AND DESIGN: Antenatal clinic of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria...
July 2016: Annals of African Medicine
Juhi Bharti, Richa Vatsa, Seema Singhal, Kallol Kumar Roy, Sunesh Kumar, Vanamail Perumal, Jyoti Meena
OBJECTIVE: Pregnancy with chronic kidney disease (CKD) is considered to be high risk. The purpose of this study was to assess the effect of pregnancy on CKD and the fetomaternal outcome in these patients. STUDY DESIGN: A retrospective observational study was conducted in the Department of Obstetrics and Gynaecology, All India Institute of medical sciences, New Delhi over a period of 11 years. A total number of 80 pregnant patients with CKD were reviewed. Staging of CKD was done according to glomerular filtration rate (GFR)...
September 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
A N Aksoy, F Aydin, S K Kucur, I Gözükara
AIM: This study aimed to investigate maternal and fetal Doppler flow parameters in term pregnant women diagnosed with fear of childbirth (FOC). MATERIALS AND METHODS: Women between 20 and 40 years with full-term singleton pregnancies (≥37 gestational weeks) were included in the study. All patients were questioned with Turkish form of Wijma Delivery Expectancy/Experience Questionnaire (W-DEQ) version A. Women with W-DEQ scores ≥85 were defined as FOC. Forty women diagnosed with FOC (FOC group) and 45 women with W-DEQ scores <85 (control group) underwent Doppler waveform analysis and the pulsatility index (PI) and resistance index (RI) values for uterine, umbilical, and mid cerebral arteries were recorded...
September 2016: Nigerian Journal of Clinical Practice
Nicolas Sananes, Georges E Roth, Germain A Aissi, Nicolas Meyer, Annick Bigler, Jean-Michel Bouschbacher, Christine Helmlinger, Brigitte Viville, Mélanie Guilpain, Adrien Gaudineau, Chérif Y Akladios, Israël Nisand, Bruno Langer, Christophe Vayssiere, Romain Favre
BACKGROUND: Several studies have investigated the efficacy of moxibustion with or without acupuncture for fetal version, but the results are discordant. Meta-analyses pointed out the need for robust, methodologically sound, randomized controlled trials. OBJECTIVE: The objective of this study was to assess the effectiveness of acupuncture with fire needling on acupoint BL67 for version of breech presentation. STUDY DESIGN: This was a randomized, sham-controlled, single-blinded trial, which took place in Strasbourg teaching maternity hospital, France...
September 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Mahsa Kamali, Soghra Bahmanpour
BACKGROUND: One of the major problems of the aged women or older than 35 is getting pregnant in the late fertility life. Fertility rates begin to decline gradually at the age of 30, more so at 35, and markedly at 40. Even with fertility treatments such as in vitro fertilization, women have more difficulty in getting pregnant or may deliver abnormal fetus. The purpose of this study was to assess the effects of flax seed hydroalcoholic extract on the fetal brain of aged mice and its comparison with young mice...
May 2016: Iranian Journal of Medical Sciences
Soheila Mohamadirizi, Masoumeh Kordi
BACKGROUND: Multi-dimensional self-compassion is one of the important factors predicting fetal-maternal attachment which vary among different cultures and countries. So the aim of this study was to determine the relationship between multi-dimensional, self-compassion, and fetal-maternal attachment in the prenatal period. SUBJECTS AND METHODS: This cross-sectional study was carried on 394 primigravida women to Mashhad Health Care Centers in with two stage sampling method (cluster-convenience) in the year 2014...
2016: Journal of Education and Health Promotion
Andrea Andrek, Zoltan Kekecs, Eva Hadhazi, Zack Boukydis, Katalin Varga
OBJECTIVE: To explore the factor structure of the Maternal-Fetal Attachment Scale (MFAS) and investigate its psychosocial and demographic correlates in a Hungarian sample. DESIGN: Cross-sectional survey. SETTING: Sonography clinic in a metropolitan area. PARTICIPANTS: One hundred fourteen women over the age of 18 years in the second or third trimesters of pregnancy. METHODS: Participants completed the Hungarian version of the MFAS and provided information on demographic, socioeconomic, and pregnancy-related factors...
September 2016: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
Mila Kingsbury, Murray Weeks, Nathalie MacKinnon, Jonathan Evans, Liam Mahedy, Jennifer Dykxhoorn, Ian Colman
OBJECTIVE: The fetal programming hypothesis posits that in utero exposure to stress can alter prenatal brain development and lifelong stress response. However, human studies linking objective prenatal stressors to offspring mental illness, especially depression, are rare. The purpose of this study was to examine the association between mothers' exposure to prenatal stressful life events (SLEs) and offspring depression. METHOD: The sample comprised 10,569 members of a prospective population-based cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC)...
August 2016: Journal of the American Academy of Child and Adolescent Psychiatry
Rehana Rehman, Rozina Mustafa, Mukhtiar Baig, Sara Arif, Muhammad Faisal Hashmi
BACKGROUND: The measurement of follicular output rate (FORT) has been proposed as a good indicator for evaluating follicular response to the exogenous recombinant folliclestimulating hormone (rFSH). This places FORT as a promising qualitative marker for ovarian function. The objective of the study was to determine FORT as a predictor of oocyte competence, embryo quality and clinical pregnancy after intracytoplasmic sperm injection (ICSI). MATERIALS AND METHODS: This prospective study was carried out on a group of infer- tile females (n=282) at Islamabad Clinic Serving Infertile Couples, Islamabad, Pakistan, from June 2010 till August 2013...
July 2016: International Journal of Fertility & Sterility
Ayesha Saeed, Tahira Raana, Amina Muhammad Saeed, Ayesha Humayun
BACKGROUND: In Pakistan, incidence of antenatal depression ranges from 18 to 80 %, which goes undiagnosed, resulting in maternal and neonatal implications. The current study aimed to examine the association of antenatal depression with maternal dietary intake and neonatal outcome. METHODS: A hospital-based, prospective cohort study was conducted on 94 middle class antenatal attendees coming to a tertiary care hospital in Lahore, Pakistan at the beginning of second trimester...
2016: Nutrition Journal
Konrad Gronke, Michael Kofoed-Nielsen, Andreas Diefenbach
Innate lymphoid cells (ILC) have only recently been recognized as a separate entity of the lymphoid lineage. Their subpopulations share common characteristics in terms of early development and major transcriptional circuitry with their related cousins of the T cell world. It is currently hypothesized that ILCs constitute an evolutionary older version of the lymphoid immune system. They are found at all primary entry points for pathogens such as mucosal surfaces of the lung and gastrointestinal system, the skin and the liver, which is the central contact point for pathogens that breach the intestinal barrier and enter the circulation...
July 6, 2016: Immunology Letters
A N Rosman, F Vlemmix, S Ensing, B C Opmeer, S Te Hoven, J Velzel, M de Hundt, S van den Berg, H Rota, J A M van der Post, B W J Mol, M Kok
OBJECTIVE: to assess the mode of childbirth and adverse neonatal outcomes in women with a breech presentation with or without an external cephalic version attempt, and to compare the mode of childbirth among women with successful ECV to women with a spontaneous cephalic presentation. DESIGN: prospective matched cohort study. SETTING: 25 clusters (hospitals and its referring midwifery practices) in the Netherlands. Data of the Netherlands perinatal registry for the matched cohort...
August 2016: Midwifery
Tigist Endale, Netsanet Fentahun, Desta Gemada, Mamusha Aman Hussen
BACKGROUND: Premature rupture of membrane (PROM) is linked to significant maternal prenatal mortalities and morbidity. In Ethiopia, where maternal mortality is still high, the maternal and fetal outcomes in PROM is very important to decrease maternal and child mortality and for better management and prevention of complications. Thus, this study aimed to detect the maternal and fetal outcomes and associated factors in term PROM at Mizan-Aman General Hospital, south-west Ethiopia. METHODS: A retrospective cross sectional study was conducted using data available at Mizan-Aman General Hospital during a period of 3 years (January 2011 to December 2013)...
2016: World Journal of Emergency Medicine
Fionnuala Mone, Barbara McConnell, Andrew Thompson, Ricardo Segurado, Peter Hepper, Moira C Stewart, James C Dornan, Stephen Ong, Fionnuala M McAuliffe, Michael D Shields
OBJECTIVE: To determine whether an elevated fetal umbilical artery Doppler (UAD) pulsatility index (PI) at 28 weeks' gestation, in the absence of fetal growth restriction (FGR) and prematurity, is associated with adverse neurocognitive outcome in children aged 12 years. METHODS: Prospective cohort study, comparing children with a normal fetal UAD PI (<90th centile) (n=110) and those with an elevated PI (≥90th centile) (n=40). UAD was performed at 28, 32 and 34 weeks gestation...
2016: BMJ Open
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