keyword
https://read.qxmd.com/read/38539039/systematic-application-of-sica-ped-protocol-for-central-venous-catheterization-in-neonates-a-prospective-clinical-study-on-104-cases
#1
JOURNAL ARTICLE
Ferdinando Spagnuolo, Anna Maietta, Umberto Pugliese, Emanuele Lettieri, Fabrizio Minopoli, Nicola Coppola, Marco La Verde, Margherita Macera, Caterina Monari, Lorenzo Onorato, Mauro Carpentieri
BACKGROUND: Catheterization of central vessels can be associated with early and late, potentially fatal complications. A proactive approach is imperative to reduce the frequency and magnitude of adverse events. Recently, the GAVeCeLT has proposed a protocol called SICA-PED (i.e. Safe Insertion of Central Access in Pediatric patients) and includes seven evidence-based strategies. METHODS: Through a single-center prospective observational study, the authors wanted to consolidate the efficacy and safety of these protocol in newborns...
March 27, 2024: Journal of Vascular Access
https://read.qxmd.com/read/38517378/toward-subtalar-joint-axis-driven-computer-aided-design-and-computer-aided-manufacturing-foot-orthoses-reliability-of-a-noninvasive-clinical-scanning-protocol
#2
JOURNAL ARTICLE
Clément Potier, Kurt Claeys, Kevin Deschamps
BACKGROUND: The subtalar joint axis (STJA) occupies a key role in the dynamics of the lower limb kinetic chain, and its location has a wide interindividual variability. It has been suggested that considering the STJA location when designing foot orthoses may help to apply the required mechanical dose. However, the evidence is more anecdotal than empirical. OBJECTIVE: This study aimed to evaluate the reliability of the STJA digitization, a procedure combining the clinical determination of the functional STJA location and its subsequent 3-dimensional (3D) scanning...
March 22, 2024: Prosthetics and Orthotics International
https://read.qxmd.com/read/38512336/a-web-based-physical-activity-promotion-intervention-for-inactive-parent-child-dyads-protocol-for-a-randomized-controlled-trial
#3
JOURNAL ARTICLE
Daniel Phipps, Weldon Thomas Green, Reetta Aho, Eeva Kettunen, Stuart Biddle, Kyra Hamilton, Arto Laukkanen, Kaisa Aunola, Derwin King Chan, Nelli Hankonen, Mary Hassandra, Tommi Kärkkäinen, Virpi-Liisa Kykyri, Juho Polet, Ryan Rhodes, Montse C Ruiz, Arja Sääkslahti, Jekaterina Schneider, Hanna-Mari Toivonen, Taru Lintunen, Martin Hagger, Keegan Knittle
BACKGROUND: Low levels of physical activity are associated with numerous adverse health outcomes, yet sedentary lifestyles are common among both children and adults. Physical activity levels tend to decline steeply among children aged between 8 and 12 years, even though children's behavioral patterns are largely governed by familial structures. Similarly, parents' activity levels have been generally reported as lower than those of nonparents of comparable age. For this reason, family-based physical activity promotion interventions are a potentially valuable and relatively underresearched method for mitigating physical activity declines as children develop into adolescents and for increasing physical activity in parents...
March 21, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38507158/tunnel-ultrasound-can-guide-the-use-of-peritoneal-dialysis-catheter-exit-site-relocation-by-external-splicing-and-cuff-removal-in-refractory-tunnel-infection
#4
JOURNAL ARTICLE
Luca Nardelli, Antonio Scalamogna, Federica Tripodi, Chiara De Liso, Carlo Alfieri, Giuseppe Castellano
BACKGROUND: Peritoneal dialysis (PD) catheter related infections continue to be a major cause of morbidity and transfer to hemodialysis (HD) in PD patients. The treatment of tunnel infection (TI) could be challenging, especially when the infection involves the superficial cuff requiring the removal of the catheter. To spare the patient the loss of the catheter and the transfer to HD, several mini-invasive surgical techniques have been proposed as rescue therapy. Furthermore, nowadays, the rapid growth of digital technology has enormously increased the diagnostic sensibility of the echo signal allowing to accurately defines the extent of the infectious process along the PD catheter tunnel...
March 20, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38506519/contralateral-nasofrontal-trephination-a-novel-corridor-for-a-dual-port-approach-to-the-petrous-apex
#5
JOURNAL ARTICLE
Moataz D Abouammo, Maithrea S Narayanan, Mohammad Bilal Alsavaf, Mohammed Alwabili, Jaskaran Singh Gosal, Govind S Bhuskute, Kyle C Wu, Basit A Jawad, Kyle K VanKoevering, Ricardo L Carrau, Daniel M Prevedello
BACKGROUND AND OBJECTIVES: Expanded endonasal approaches (EEAs) have proven safe and effective in treating select petrous apex (PA) pathologies. Angled endoscopes and instruments have expanded indications for such approaches; however, the complex neurovascular anatomy surrounding the petrous region remains a significant challenge. This study evaluates the feasibility, anatomic aspects, and limitations of a contralateral nasofrontal trephination (CNT) route as a complementary corridor improving access to the PA...
March 20, 2024: Operative Neurosurgery (Hagerstown, Md.)
https://read.qxmd.com/read/38501722/conventional-vs-augmented-reality-guided-lateral-calcaneal-lengthening-simulated-in-a-foot-bone-model
#6
JOURNAL ARTICLE
Maksym Polt, Arnd F Viehöfer, Fabio A Casari, Florian B Imhoff, Stephan H Wirth, Stefan M Zimmermann
BACKGROUND: Acquired adult flatfoot deformity (AAFD) results in a loss of the medial longitudinal arch of the foot and dysfunction of the posteromedial soft tissues. Hintermann osteotomy (H-O) is often used to treat stage II AAFD. The procedure is challenging because of variations in the subtalar facets and limited intraoperative visibility. We aimed to assess the impact of augmented reality (AR) guidance on surgical accuracy and the facet violation rate. METHODS: Sixty AR-guided and 60 conventional osteotomies were performed on foot bone models...
March 19, 2024: Foot & Ankle International
https://read.qxmd.com/read/38482947/management-of-neonatal-airway-obstruction-a-point-counterpoint-ethical-discussion
#7
JOURNAL ARTICLE
Rohit Nallani, Carrie L Francis, Asdis F Wagner, Jason R Brown
No abstract text is available yet for this article.
March 14, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38479169/impact-of-pharmacogenomic-profiles-on-post-surgical-pain-following-laparotomy-for-gynecologic-pathology
#8
JOURNAL ARTICLE
Gretchen E Glaser, Brandon Maddy, Amanika Kumar, Karen Ishitani, Maureen A Lemens, Kristine Hanson, Ann M Moyer, Elizabeth Habermann, Sean C Dowdy
OBJECTIVES: The aim of this prospective study was to compare perioperative opioid use in women by status of CYP2D6, a highly polymorphic pharmacogene relevant to opioid metabolism. METHODS: Patients undergoing laparotomy were prospectively recruited and provided a preoperative saliva swab for a pharmacogenomic (PGx) gene panel. Postoperative opioid usage and pain scores were evaluated via chart review and a phone survey. Pharmacogenes known to be relevant to opioid metabolism were genotyped, and opioid metabolizing activity predicted by CYP2D6 genotyping...
March 12, 2024: Gynecologic Oncology
https://read.qxmd.com/read/38478085/transient-ureteral-obstruction-after-mini-percutaneous-nephrolithotomy-is-associated-with-stone-volume-and-location-results-from-a-single-center-real-life-study
#9
JOURNAL ARTICLE
Marco Nizzardo, Stefano Paolo Zanetti, Andrea Marmiroli, Gianpaolo Lucignani, Matteo Turetti, Carlo Silvani, Franco Gadda, Fabrizio Longo, Elisa De Lorenzis, Giancarlo Albo, Andrea Salonia, Emanuele Montanari, Luca Boeri
PURPOSE: To evaluate the rate of and predictors of ureteral obstruction after mini-percutaneous nephrolithotomy (mPCNL) for kidney stones. METHODS: We analyzed data from 263 consecutive patients who underwent mPCNL at a single tertiary referral academic between 01/2016 and 11/2022. Patient's demographics, stone characteristics, and operative data were collected. A nephrostomy tube was placed as the only exit strategy in each procedure. On postoperative day 2, an antegrade pyelography was performed to assess ureteral canalization...
March 13, 2024: World Journal of Urology
https://read.qxmd.com/read/38477178/comparison-of-unplanned-urgent-start-versus-conventional-start-peritoneal-dialysis-a-systematic-review-and-meta-analysis
#10
REVIEW
Yunfen Xu, Weizhong Jiang
The timing of peritoneal dialysis (PD) initiation, whether conventional-start (planned) or urgent-start (unplanned), may impact the outcomes of PD and the rate of associated complications in individuals with chronic kidney disease (CKD). The goal of this study was to evaluate the effects of unplanned/urgent-start PD versus conventional-start PD in this cohort of patients. Electronic search of MEDLINE (via PubMed), EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), and Scopus databases was done from inception until July 2023 for studies reporting outcomes of unplanned/urgent-start and conventional-start PD in CKD patients...
March 13, 2024: Seminars in Dialysis
https://read.qxmd.com/read/38469169/building-resilience-and-attachment-in-vulnerable-adolescents-the-feasibility-of-a-virtually-delivered-group-intervention-for-adolescents-with-suicidal-ideation-and-their-caregivers
#11
JOURNAL ARTICLE
Nicole Sheridan, Allison Kennedy, Clare Gray, Leigh Dunn, Jayme Stewart, Hannah Elliott, Kendra Carnrite, Ademola Adeponle, Paula Cloutier
BACKGROUND: The COVID-19 pandemic required many interventions to be conducted virtually. Building Resilience and Attachment in Vulnerable Adolescents (BRAVA) is a group intervention designed for adolescents and their caregivers to reduce adolescent suicidal ideation (SI). OBJECTIVE: We aimed to adapt BRAVA for virtual delivery and evaluate its acceptability and feasibility. METHODS: We conducted an 8-week pre-post trial between October and December 2020...
2024: Telemedicine reports
https://read.qxmd.com/read/38468671/inferior-temporal-quadrantanopia-associated-with-pituitary-adenomas-and-a-potential-mechanism-of-excessive-optic-nerve-bending
#12
JOURNAL ARTICLE
Munehiro Demura, Yasuo Sasagawa, Yasuhiko Hayashi, Osamu Tachibana, Mitsutoshi Nakada
BACKGROUND: Pituitary adenomas show typical visual field defects that begin superiorly and progress inferiorly. The cause of atypical visual field defects that start inferiorly remains unclear. This study aimed to understand this phenomenon using magnetic resonance imaging (MRI). METHODS: A total of 220 patients with pituitary adenomas underwent a visual field assessment of both eyes. Preoperative visual fields were assessed and classified into two types: superior quadrantanopia (typical) and inferior quadrantanopia (atypical)...
2024: Surgical Neurology International
https://read.qxmd.com/read/38468667/traumatic-penetrating-head-injury-by-crossbow-projectiles-a-case-report-and-literature-review
#13
Moath Abdullah Khayat, Hassan Khayat, Mohamed Rashed Alhantoobi, Majid Aljoghaiman, Doron D Sommer, Almunder Algird, Daipayan Guha
BACKGROUND: Low-energy penetrating head injuries caused by arrows are relatively uncommon. The objective of this report is to describe a case presentation and management of self-inflicted intracranial injury using a crossbow and to provide a relevant literature review. CASE REPORT: A 31-year-old man with a previous psychiatric history sustained a self-inflicted injury using a crossbow that he bought from a department store. The patient arrived neurologically intact at the hospital, fully awake and oriented...
2024: Surgical Neurology International
https://read.qxmd.com/read/38458921/accuracy-in-reporting-incontinence-in-adults-with-spina-bifida-a-pilot-study
#14
JOURNAL ARTICLE
Konrad M Szymanski, Rosalia Misseri, Devon J Hensel
BACKGROUND: The accuracy of self-reported urinary incontinence (UI) and fecal incontinence (FI) among adults with spina bifida (SB) is unknown. We aimed to quantify the accuracy of self-reported recall incontinence in the last 4 weeks using prospective diary data. METHODS: Adults with SB were enrolled via patient advocacy groups in a larger 30-day smartphone-based ecological momentary assessment study of daily well-being and incontinence. We examined agreement between yes/no questions on exit questionnaires ("In the last 4 weeks, did you leak any urine and get your underwear, pads, pull-ups or disposable underwear wet?") and 30-day diaries...
February 24, 2024: Journal of Pediatric Urology
https://read.qxmd.com/read/38441870/comparison-of-immediate-start-peritoneal-dialysis-without-break-in-period-and-conventional-start-peritoneal-dialysis-a-two-center-retrospective-audit
#15
JOURNAL ARTICLE
Suwikran Wongpraphairot, Kitjapong Choopun, Tharinee Sriphatphiriyakun, Apiradee Titawatanakul, Virasakdi Chongsuvivatwong, Atthaphong Phongphithakchai
PURPOSE: Immediate-start peritoneal dialysis (PD) has emerged as a strategy for patients in need of urgent dialysis. However, the ideal timing for initiating this procedure remains uncertain. In this study, we aimed to compare complications and outcomes between immediate-start PD and conventional-start PD. METHODS: We performed a two-center retrospective cohort study between 1 January 2015 and 31 May 2020. Patients who underwent PD were divided into immediate-start PD (without break-in period) and conventional-start PD group (break-in period within at least 14 days)...
March 5, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38424355/sub-gluteal-ligation-of-the-internal-pudendal-vein-for-management-of-veno-occlusive-erectile-dysfunction-shaeer-s-vein-ligation-i-the-cadaveric-study
#16
JOURNAL ARTICLE
Osama Shaeer, Ehab A A El-Shaarawy, Hossam Y Emam, Islam Elsisi, Eslam Sokar, Kamal Shaeer
Vein ligation for veno-occlusive erectile dysfunction is being abandoned due to the recurrence rate. Among the reasons for failure is inability to ligate the deep system of veins; the internal pudendal vein. The vein exits the pelvis in the gluteal region, from the lesser sciatic foramen to the greater sciatic foramen, coursing over the ischial spine and sacro-spinous ligament, under the gluteus maximus. This work aims to verify feasibility of the first surgical procedure to ligate the internal pudendal vein through the gluteal approach...
February 29, 2024: International Journal of Impotence Research
https://read.qxmd.com/read/38408512/exploration-of-bromodomain-ligand-linker-conjugation-sites-for-efficient-cbp-p300-heterobifunctional-degrader-activity
#17
JOURNAL ARTICLE
Praveen Kumar Tiwari, Sai Reddy Doda, Raghu Vannam, Manish Hudlikar, Drew Harrison, Samuel Ojeda, Sumit Rai, Ann-Sophie Koglin, Angelique Nguyen Gilbert, Christopher J Ott
Synthesis of proteolysis targeting chimeras (PROTACs) involves conjugation of an E3 ligase binding ligand to a ligand targeting a protein of interest via a rigid or flexible chemical linker. The choice of linker conjugation site on these ligands can be informed by structural analysis of ligand-target binding modes, the feasibility of synthetic procedures to access specific sites, and computational modeling of predicted ternary complex formations. Small molecules that target bromodomains - epigenetic readers of lysine acetylation - typically offer several potential options for linker conjugation sites...
February 24, 2024: Bioorganic & Medicinal Chemistry Letters
https://read.qxmd.com/read/38406109/etiological-factors-affecting-single-versus-multiple-tunneled-hemodialysis-catheter-cuff-extrusions-in-the-saudi-population
#18
JOURNAL ARTICLE
Hammad Raza, Muhammad Nauman Hashmi, Muhammad A Khan, Manuel Troncoso, Agamon Christallone, Jawad Alhammouri, Mohamed Hafez, Muhammad Shakeel Khan, Fayez Hejaili
OBJECTIVE: To identify underlying factors associated with single versus multiple expulsions of tunneled hemodialysis catheter cuffs and their associated complications. MATERIALS AND METHODS: A multicenter, five-year retrospective data analysis was conducted on hemodialysis patients with tunneled catheters. Patient data included age, gender, BMI, and associated comorbidities. The type of procedure (new tunnel insertion vs. exchange), exit site infection, and catheter-related bloodstream infection (CRBSI) were also included...
January 2024: Curēus
https://read.qxmd.com/read/38403236/feasibility-of-carbon-dioxide-insufflation-and-impact-on-epicardial-approach-utilization-for-ventricular-tachycardia-ablation-in-a-mid-volume-referral-center
#19
JOURNAL ARTICLE
Giulio Zucchelli, Matteo Parollo, Andrea Di Cori, Lorenzo Mazzocchetti, Luca Segreti, Gino Grifoni, Marco Torre, Sara Sbragi, Raffaele De Lucia, Valentina Barletta, Antonio Canu, Stefano Viani, Maria Grazia Bongiorni
BACKGROUND: Epicardial access is often crucial for successful ventricular tachycardia (VT) ablation, but it's often burdened by significant procedural risk. Intentional coronary vein exit and intrapericardial CO2 insufflation (EpiCO2 ) can facilitate subxiphoid pericardial access. OBJECTIVE: This prospective study aims at assessing procedural feasibility, safety and impact of the introduction of intrapericardial CO2 insufflation for epicardial access in a referral center for VT ablation...
February 23, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38387645/does-a-sign-restricting-operating-room-access-reduce-staff-traffic-in-the-surgical-department
#20
JOURNAL ARTICLE
Roger Erivan, Guillaume Villatte, Arthur Haverlan, Claude Alain Roullet, Lemlih Ouchchane, Stéphane Descamps, Stéphane Boisgard
INTRODUCTION: Infections following orthopedic surgery are rare but difficult to treat. Among the prevention measures reviewed during the Musculoskeletal Infection Society's (MSIS) 2023 international consensus meeting, the only strategy to obtain 100% agreement was the control of traffic in and out of the operating room (OR). Although this recommendation makes good sense, to our knowledge, it has not been previously investigated in a comparative study. We, therefore, conducted a prospective, observational, before-and-after study of the implementation of an informational sign designed to limit traffic in and out of the OR to 1) determine its impact on door openings and the number of people present during orthopedic surgery and 2) assess the risk of surgical site infection after the institution of this sign...
February 20, 2024: Orthopaedics & Traumatology, Surgery & Research: OTSR
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