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https://www.readbyqxmd.com/read/29323421/head-and-neck-cancer-tumor-seeding-at-the-percutaneous-endoscopic-gastrostomy-site
#1
REVIEW
June R Greaves
The National Institutes of Health National Cancer Institute estimates that over 13,000 new cases of head and neck cancer (HNC) will be diagnosed in 2017. Patients with HNC often require enteral nutrition (EN) via gastrostomy tube to provide nutrition support and hydration because of tumor obstruction of the oropharynx and/or cumulative effects of chemoradiation therapy. The percutaneous endoscopic gastrostomy (PEG) tube has become the preferred technique for EN access because placement is considered a minimally invasive procedure...
January 11, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29321139/bmp-smad-pathway-promotes-neurogenesis-of-midbrain-dopaminergic-neurons-in-vivo-and-in-human-induced-pluripotent-and-neural-stem-cells
#2
V M Jovanovic, A Salti, H Tilleman, K Zega, M M Jukic, H Zou, R H Friedel, N Prakash, S Blaess, F Edenhofer, C Brodski
The embryonic formation of midbrain dopaminergic (mDA) neurons in vivo provides critical guidelines for the in vitro differentiation of mDA neurons from stem cells, currently being developed for Parkinson's disease cell replacement therapy. Bone morphogenetic protein (BMP)/SMAD inhibition is routinely used during early steps of stem cell differentiation protocols, including for the generation of mDA neurons. However, the function of the BMP/SMAD pathway for in vivo specification of mammalian mDA neurons is virtually unknown...
January 10, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29299514/percutaneous-gastrostomy-site-metastasis-from-head-and-neck-tumors-a-single-institution-case-series
#3
James S Metkus, David Cognetti, Joseph Curry
Objectives: Head and neck cancer (HNC) patients often require percutaneous gastrostomy (PEG) tube placement due to malnutrition and dysphagia. While beneficial, PEG tube placement can cause a rare but reportable complication of metastasis of the original tumor to the gastrostomy exit site. The objectives of this case series were to present HNC patients at a single institution that developed PEG tube metastases, their subsequent treatment, and review of the literature for similar cases...
December 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/29296104/addressing-the-dual-health-epidemics-of-hiv-and-sexual-abuse-among-children-and-adolescents-in-kenya-uptake-of-hiv-counseling-and-post-exposure-prophylaxis
#4
Carolyne Ajema, Charity Mbugua, Peter Memiah, Camille Wood, Courtney Cook, Ronald Kotut, Lina Digolo
Purpose: Child sexual abuse and HIV are key health challenges in Kenya. In 2015, LVCT Health conducted a study aimed at assessing the quality of HIV-related services offered to child survivors of sexual violence in public health facilities. Materials and methods: A qualitative data collection approach was utilized. Qualitative data were collected through in-depth interviews with 31 providers. Quantitative methods included a retrospective review of 164 records of child survivors of rape who had accessed services 6 months prior to the commencement of the study...
2018: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/29294811/playing-by-the-rules-agency-policy-and-procedure-in-service-experience-of-ipv-survivors
#5
Leila Wood, Laurie Cook Heffron, Molly Voyles, Shanti Kulkarni
More than 1,800 programs exist in the United States, providing not only shelter but also transitional housing, advocacy and support, transportation, legal aid, and group and individual counseling for women who have experienced intimate partner violence (IPV). Shelter and transitional housing provide critical support for survivors, but have also been critiqued for having too many restrictive rules and code of conduct. More information is needed about the impact of rules and agency policy on women seeking services in IPV residential settings...
June 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29244269/current-trends-of-percutaneous-nephrolithotomy-in-a-developing-country
#6
Carlos A Batagello, Fabio Carvalho Vicentini, Giovanni Scala Marchini, Fabio Cesar Miranda Torricelli, Miguel Srougi, Willian Carlos Nahas, Eduardo Mazzucchi
INTRODUCTION: To present the current practice patterns on percutaneous nephrolithotomy (PCNL) in a developing country. MATERIALS AND METHODS: A survey was offered to Brazilian urologists during the II International Endourology Symposium held in Sao Paulo, in 2015. The first seven questions were related to demographic data while the 20 remaining were directed to urologists who performed PCNL. RESULTS: From 250 participants, 100 replied to the survey, 81% performed PCNL and 60...
December 18, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29244156/percutaneous-increase-of-mitral-leaflet-coaptation-length-after-mitral-valve-repair-results-from-a-preclinical-study
#7
Piergiorgio Tozzi, Giuseppe Siniscalchi, Enrico Ferrari, Matthias Kirsch, Daniel Hayoz
OBJECTIVES: The failure of mitral repairs can be the result of inadequate leaflet coaptation length (CL< 8 mm at the A2-P2 level). A new annuloplasty ring conceived by the authors enables post-surgical CL increase using percutaneous balloon catheter technology. We conducted preclinical studies to assess the in vivo feasibility of the procedure and the safety of the postimplant deformable mitral ring. METHODS: The new annuloplasty ring allows the percutaneous and progressive displacement of each of the 3 anatomical regions of the posterior mitral annulus towards the anterior...
December 13, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29233749/an-amendment-to-the-neidre-and-macnab-classification-system-for-lumbosacral-nerve-root-anomaly-and-its-implication-in-percutaneous-endoscopic-lumbar-discectomy
#8
Chen Yu, Chang Zhengqi, Yu Xiuchun
BACKGROUND: Lumbar disc herniation complicated with nerve root anomaly presents great challenges to diagnosis and treatment, improper selection of surgical procedures may cause inferior outcomes and neurological injury. CASE DESCRIPTION: A 66-year old male presented with low back pain and radicular symptoms involving bilateral L-5 and S-1 nerve roots. Instead of percutaneous endoscopic lumbar discectomy, aggressive decompression was carried out due to deviation between examination and imaging findings...
December 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29233377/application-of-a-systematic-approach-to-evaluating-psychometric-properties-of-a-cumulative-exit-from-degree-objective-structured-clinical-examination-osce
#9
Ahmed Hesham Sobh, Zubin Austin, Mohamed Izham M I, Mohammad I Diab, Kyle John Wilby
BACKGROUND AND PURPOSE: Objective structured clinical examinations (OSCEs) are considered gold standard performance-based assessments yet comprehensive evaluation data is currently lacking. The objective of this study was to critically evaluate the psychometric properties of a cumulative OSCE for graduating pharmacy students in Qatar for which policies and procedures were adapted from a Canadian context. EDUCATIONAL ACTIVITY AND SETTING: A 10-station OSCE was conducted for graduating students in Qatar...
November 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29217372/acute-peritoneal-dialysis-in-neonatal-intensive-care-unit-an-8-year-experience-of-a-referral-hospital
#10
Aslihan Kara, Metin Kaya Gurgoze, Mustafa Aydin, Erdal Taskin, Unal Bakal, Aysen Orman
BACKGROUND: The aim of present study was to evaluate the indications, complications and outcomes of acute peritoneal dialysis (APD) in neonates at a referral university hospital during the previous 8 years. METHODS: This retrospective analysis included a total of 52 newborn infants who underwent APD in a neonatal intensive care unit between January 2008 and March 2016. Demographic, clinical, laboratory and microbiological data were extracted from patients' medical files...
November 16, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29187760/the-exit-ex-utero-intrapartum-treatment-procedure-from-the-paediatric-ent-perspective
#11
B Pucher, J Szydlowski, K Jonczyk-Potoczna, J Sroczynski
The main principle of the EXIT procedure is to maintain uteroplacental circulation with neonatal anaesthesia by controlled uterine hypotonia. This enables securing the foetal airways and decompress or resect large neck and mediastinal foetal masses. The authors present their experience with use of the EXIT procedure in 7 foetuses in whom evaluation and management of the airways were performed. In 4 patients, the neck mass was surgically removed in the neonatal period, in 1 the propranolol treatment was introduced...
November 30, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29149879/risk-management-of-emergency-service-vehicle-crashes-in-the-united-states-fire-service-process-outputs-and-recommendations
#12
David P Bui, Keshia P Porter, Stephanie Griffin, Dustin D French, Alesia M Jung, Stephen Crothers, Jefferey L Burgess
BACKGROUND: Emergency service vehicle crashes (ESVCs) are a leading cause of death in the United States fire service. Risk management (RM) is a proactive process for identifying occupational risks and reducing hazards and unwanted events through an iterative process of scoping hazards, risk assessment, and implementing controls. We describe the process, outputs, and lessons learned from the application of a proactive RM process to reduce ESVCs in US fire departments. METHODS: Three fire departments representative of urban, suburban, and rural geographies, participated in a facilitated RM process delivered through focus groups and stakeholder discussion...
November 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29138760/cardiac-surgery-after-heart-transplantation-elective-operation-or-last-exit-strategy
#13
Johannes Goekler, Andreas Zuckermann, Emilio Osorio, Faris F Brkic, Keziban Uyanik-Uenal, Guenther Laufer, Arezu Aliabadi-Zuckermann
Background: Because of improved long-term survival after heart transplantation (HTx), late graft pathologies such as valvular disease or cardiac allograft vasculopathy (CAV) might need surgical intervention to enhance longer survival and ensure quality of life. To this date, there exist no guidelines for indication of cardiac surgery other than retransplantation after HTx. Methods: In this retrospective, single-center study, we evaluated patients who underwent cardiac surgery after HTx at our institution...
October 2017: Transplantation Direct
https://www.readbyqxmd.com/read/29122337/study-of-anatomical-variations-of-the-zygomaticofacial-foramen-and-calculation-of-reliable-reference-points-for-operation
#14
A Ferro, S Basyuni, C Brassett, V Santhanam
Dissection on to the facial aspect of the zygoma is common in procedures of the midface for trauma, craniofacial deformity, and cosmesis. These procedures carry the risk of injury to the neurovascular structures that exit from the zygomaticofacial foramen (ZFF). The purpose of this study was to map the ZFF, and to establish reliable reference points from which to identify it before and during operation. We also aimed to compare the anatomy of the ZFF between sexes and among geographical populations. A total of 429 adult skulls from nine geographical sites were used...
November 6, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29066932/efficiency-of-spinal-anesthesia-versus-general-anesthesia-for-lumbar-spinal-surgery-a-retrospective-analysis-of-544-patients
#15
John T Pierce, Guy Kositratna, Mark A Attiah, Michael J Kallan, Rebecca Koenigsberg, Peter Syre, David Wyler, Paul J Marcotte, W Andrew Kofke, William C Welch
BACKGROUND: Previous studies have shown varying results in selected outcomes when directly comparing spinal anesthesia to general in lumbar surgery. Some studies have shown reduced surgical time, postoperative pain, time in the postanesthesia care unit (PACU), incidence of urinary retention, postoperative nausea, and more favorable cost-effectiveness with spinal anesthesia. Despite these results, the current literature has also shown contradictory results in between-group comparisons...
2017: Local and Regional Anesthesia
https://www.readbyqxmd.com/read/29037190/do-mobile-clinics-provide-high-quality-antenatal-care-a-comparison-of-care-delivery-knowledge-outcomes-and-perception-of-quality-of-care-between-fixed-and-mobile-clinics-in-central-haiti
#16
Erica Phillips, Rebecca J Stoltzfus, Lesly Michaud, Gracia Lionel Fils Pierre, Francoise Vermeylen, David Pelletier
BACKGROUND: Antenatal care (ANC) is an important health service for women in developing countries, with numerous proven benefits. Global coverage of ANC has steadily increased over the past 30 years, in part due to increased community-based outreach. However, commensurate improvements in health outcomes such as reductions in the prevalence of maternal anemia and infants born small-for-gestational age have not been achieved, even with increased coverage, indicating that quality of care may be inadequate...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29018317/jake%C3%A2-multimodal-data-capture-system-insights-from-an-observational-study-of-autism-spectrum-disorder
#17
Seth L Ness, Nikolay V Manyakov, Abigail Bangerter, David Lewin, Shyla Jagannatha, Matthew Boice, Andrew Skalkin, Geraldine Dawson, Yvette M Janvier, Matthew S Goodwin, Robert Hendren, Bennett Leventhal, Frederick Shic, Walter Cioccia, Gahan Pandina
Objective: To test usability and optimize the Janssen Autism Knowledge Engine (JAKE®) system's components, biosensors, and procedures used for objective measurement of core and associated symptoms of autism spectrum disorder (ASD) in clinical trials. Methods: A prospective, observational study of 29 children and adolescents with ASD using the JAKE system was conducted at three sites in the United States. This study was designed to establish the feasibility of the JAKE system and to learn practical aspects of its implementation...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28992728/use-of-ex-utero-intrapartum-treatment-procedure-in-fetal-neck-and-high-airway-anomalies-report-of-four-clinical-cases
#18
Jakub Kornacki, Jarosław Szydłowski, Jana Skrzypczak, Małgorzata Szczepańska, Marcin Rajewski, Agnieszka Koziołek, Michał Gaca, Ewa Wender-Ożegowska
PURPOSE: To present antenatal management and use of ex utero intrapartum treatment (EXIT) in different fetal neck and high airway anomalies. MATERIAL AND METHODS: We have presented four different cases of fetal neck or airway pathology which were indications for EXIT, at our department. RESULTS: In three cases of fetal neck tumors, the primary precise antenatal diagnoses of tumors were confirmed after birth. The airways of all three fetuses were properly secured during EXIT by laryngologist...
October 26, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28980546/-the-possibility-of-using-the-synthetic-compound-for-the-purpose-of-modeling-of-the-human-soft-tissues-in-connection-with-the-evaluation-of-gunshot-damages
#19
I V Latyshov, V A Vasil'ev, I V Zaporotskova, T A Ermakova
The necessity of using a simulator of human soft tissues for the purpose of criminalistic and forensic medical expertises is dictated by the requirements put forward by the expert practice. The objective of the present study was to develop a synthetic simulator of the human soft tissues (compound) to ensure reliability of comparative criminalistics and forensic medical studies for the evaluation of gunshot injuries. The synthetic compound was prepared by mixing up the petroleum and/or synthetic oil with a polymeric thickening agent...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28976806/magnetic-compression-anastomosis-magnamosis-for-functional-undiversion-of-ileostomy-in-pediatric-patients
#20
Luzia Toselli, Marcelo Martinez-Ferro, Guillermo Cervio, Dillon Kwiat, Jill Imamura-Ching, Claire E Graves, Brandon Gaston, Michael Harrison
INTRODUCTION: Magnamosis forms a compression anastomosis using self-aligning magnetic Harrison rings. The device has been approved by the Food and Drug Administration for first-in-human testing and has been applied in adults for intestinal anastomosis during urologic reconstructions. We now report the first cases of magnamosis to functionally undivert the fecal stream from a previously created loop ileostomy in pediatric patients. MATERIALS AND METHODS: Case 1: A 4-year-old male underwent a diverting loop ileostomy for malignant bowel obstruction...
December 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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