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Methodology, evidence-based medicine, science

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https://www.readbyqxmd.com/read/29132914/comparison-of-cyclopentolate-versus-tropicamide-cycloplegia-a-systematic-review-and-meta-analysis
#1
Negareh Yazdani, Ramin Sadeghi, Hamed Momeni-Moghaddam, Leili Zarifmahmoudi, Asieh Ehsaei
PURPOSE: The aim of the present meta-analysis is to compare the efficacy of cyclopentolate and tropicamide in controlling accommodation during refraction. METHODS: A comprehensive literature search was performed in PubMed, Scopus, Science direct and Ovid databases by the key words: "tropicamide"; "cyclopentolate"; "cycloplegia" and "cycloplegic" from inception to April 2016. Methodological quality of the literature was evaluated according to the Oxford Center for Evidence Based Medicine and modified Newcastle-Ottawa scale...
November 10, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/29124632/revealed-and-stated-preferences-of-decision-makers-for-priority-setting-in-health-technology-assessment-a-systematic-review
#2
REVIEW
Peter Ghijben, Yuanyuan Gu, Emily Lancsar, Silva Zavarsek
BACKGROUND: There is much interest from stakeholders in understanding how health technology assessment (HTA) committees make national funding decisions for health technologies. A growing literature has analysed past decisions by committees (revealed preference, RP studies) and hypothetical decisions by committee members (stated preference, SP studies) to identify factors influencing decisions and assess their importance. OBJECTIVES: A systematic review of the literature was undertaken to provide insight into committee preferences for these factors (after controlling for other factors) and the methods used to elicit them...
November 9, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29121042/polish-translation-of-the-anatomical-quality-assurance-aqua-checklist-new-guidelines-for-reporting-in-original-anatomical-studies
#3
Brandon Michael Henry, Agata Marcinów, Przemysław Pękala, Dominik Taterra, Marios Loukas, R Shane Tubss, Jerzy A Walocha, Krzysztof A Tomaszewski
Recently, an improvement of the quality of reporting and methodology in original research has been observed. Major fields in research have introduced checklists aimed at promoting clear and univocal reporting of methods and results. The basis of evidence-based medicine (EBM) lies in transparent reporting of primary studies. Although clinical research progressed rapidly into evidence-based guidelines, the basic sciences, including anatomy, just recently started to use the rules of EBM. No anatomy-specific standardized research checklist has been introduced so far...
2017: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/28987076/potential-facilitators-and-barriers-to-awareness-of-n-of-1-trials-for-physicians-in-traditional-chinese-medicine
#4
Jiang Li, Dang Wei, Junqiang Niu, Min Yang, Long Ge, Xiaoqin Wang, Wenzhen Yuan, Jinhui Tian, Hongcai Shang, Jingbo Zhai, Kehu Yang, Min Dai
Context • N-of-1 trials are multiple crossover trials with randomized and blinded methods, conducted with a single participant to evaluate the effectiveness and safety of a therapy. They can be a helpful tool for enriching clinical research for traditional Chinese medicine (TCM), but the approach has gained little traction in TCM. Information is needed before supporters of the trials can pursue a change to that status. Objective • The study intended to obtain data needed to support TCM clinicians' adoption of N-of-1 trials...
October 2, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28952872/kinematics-of-the-spine-during-sit-to-stand-using-motion-analysis-systems-a-systematic-review-of-literature
#5
Mohammad Reza Pourahmadi, Ismail Ebrahimi Takamjani, Shapour Jaberzadeh, Javad Sarrafzadeh, Mohammad Ali Sanjari, Rasool Bagheri, Morteza Taghipour
BACKGROUND CONTEXT: Clinical evaluation of the spine is commonplace in musculoskeletal therapies such as physiotherapy, physical medicine/rehabilitation, osteopathic, and chiropractic clinics. Sit-to-stand (STS) is one of the most mechanically demanding of daily activities and crucial to independence. Difficulty or inability to perform STS is common in individuals with a variety of motor disabilities such as low back pain. OBJECTIVE: The purpose of this systematic review was to evaluate available evidence in literature to determine 2D and 3D kinematics of the spine during STS in patients with LBP and healthy young adult participants using motion analysis systems (electromagnetic and marker based)...
September 27, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28922704/direct-acting-antivirals-for-chronic-hepatitis-c
#6
REVIEW
Janus C Jakobsen, Emil Eik Nielsen, Joshua Feinberg, Kiran Kumar Katakam, Kristina Fobian, Goran Hauser, Goran Poropat, Snezana Djurisic, Karl Heinz Weiss, Milica Bjelakovic, Goran Bjelakovic, Sarah Louise Klingenberg, Jian Ping Liu, Dimitrinka Nikolova, Ronald L Koretz, Christian Gluud
BACKGROUND: Millions of people worldwide suffer from hepatitis C, which can lead to severe liver disease, liver cancer, and death. Direct-acting antivirals (DAAs), e.g. sofosbuvir, are relatively new and expensive interventions for chronic hepatitis C, and preliminary results suggest that DAAs may eradicate hepatitis C virus (HCV) from the blood (sustained virological response). Sustained virological response (SVR) is used by investigators and regulatory agencies as a surrogate outcome for morbidity and mortality, based solely on observational evidence...
September 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28921612/systematic-review-and-meta-analysis-of-non-pharmacological-interventions-to-reduce-the-symptoms-of-mild-to-moderate-anxiety-in-pregnant-women
#7
REVIEW
Kerry Evans, C Jane Morrell, Helen Spiby
AIM: To assess the effectiveness of non-pharmacological interventions for pregnant women with symptoms of mild to moderate anxiety. BACKGROUND: Many pregnant women experience mild to moderate symptoms of anxiety and could benefit from additional support. Non-pharmacological interventions have been suggested for use during pregnancy. DESIGN: A systematic review of randomised controlled trials. DATA SOURCES: Randomised controlled trials published since 1990, identified from electronic databases: Medline; CINAHL; Maternity and Infant Care; PsycINFO; Cochrane Database of Systematic Reviews; CENTRAL; EMBASE; Centre for Reviews and Dissemination; Social Sciences Citation Index; ASSIA; HTA Library; Joanna Briggs Institute Evidence-Based Practice database; Allied and Complementary Medicine...
September 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28902932/non-pharmacological-interventions-to-promote-the-sleep-of-patients-after-cardiac-surgery-a-systematic-review
#8
Fernanda de Souza Machado, Regina Claudia da Silva Souza, Vanessa Brito Poveda, Ana Lucia Siqueira Costa
Objective: to analyze evidence available in the literature concerning non-pharmacological interventions that are effective to treat altered sleep patterns among patients who underwent cardiac surgery. Method: systematic review conducted in the National Library of Medicine-National Institutes of Health, Cochrane Central Register of Controlled Trials, Latin American and Caribbean Health Sciences Literature, Scopus, Embase, Cumulative Index to Nursing and Allied Health Literature and PsycINFO databases, and also grey literature...
September 12, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28888225/towards-evidence-based-computational-statistics-lessons-from-clinical-research-on-the-role-and-design-of-real-data-benchmark-studies
#9
Anne-Laure Boulesteix, Rory Wilson, Alexander Hapfelmeier
BACKGROUND: The goal of medical research is to develop interventions that are in some sense superior, with respect to patient outcome, to interventions currently in use. Similarly, the goal of research in methodological computational statistics is to develop data analysis tools that are themselves superior to the existing tools. The methodology of the evaluation of medical interventions continues to be discussed extensively in the literature and it is now well accepted that medicine should be at least partly "evidence-based"...
September 9, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28876991/curriculum-redesign-in-veterinary-medicine-part-ii
#10
Maria L Macik, Kristin P Chaney, Jacqueline S Turner, Kenita S Rogers, Elizabeth M Scallan, Jodi A Korich, Debra Fowler, Lisa M Keefe
Curricular review is considered a necessary component for growth and enhancement of academic programs and requires time, energy, creativity, and persistence from both faculty and administration. On a larger scale, a comprehensive redesign effort involves forming a dedicated faculty redesign team, developing program learning outcomes, mapping the existing curriculum, and reviewing the curriculum in light of collected stakeholder data. The faculty of the Texas A&M University College of Veterinary Medicine & Biomedical Sciences (TAMU) recently embarked on a comprehensive curriculum redesign effort through partnership with the university's Center for Teaching Excellence...
2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28872668/efficacy-of-oral-pharmacological-treatments-in-dyskinetic-cerebral-palsy-a-systematic-review
#11
REVIEW
Riccardo Masson, Emanuela Pagliano, Giovanni Baranello
AIM: To evaluate the actual evidence of efficacy of oral pharmacological treatments in the management of dyskinetic cerebral palsy (CP). METHOD: A systematic review was performed according to the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology. Articles were searched for in PubMed/MEDLINE, Scopus, Web of Science, Cochrane Library, Database of Reviews of Effectiveness, OTSeeker, Physiotherapy Evidence Database, REHABDATA, and ClinicalTrials...
September 5, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28763076/-study-plan-2016-of-the-licentiate-of-medical-surgery-of-the-faculty-of-higher-studies-iztacala
#12
Adolfo René Méndez-Cruz, Xavier de Jesús Novales-Castro, Lilia Isabel Ramírez-García, Eugenio Camarena-Ocampo, Julia Reyes-Reali, Uriel Calderón-Abundes, Dante Amato
The 2016 undergraduate medical degree curriculum at the Facultad de Estudios Superiores Iztacala of the Universidad Nacional Autónoma de México (UNAM) is presented. It is the result of a long institutional reflection and academic dialog process of approximately three years, which culminated in its approval by UNAM's Academic Council for the Biology, Chemistry, and Health Sciences areas on January 25, 2016. Its most relevant characteristics are: modular organization, four knowledge areas (biomedical, methodological, socio-psychological, and humanistic and medical practice), and new modules such as Seminar of socio-psycho-biological integration; Genetics and molecular biology; Biochemistry and cellular biology; Pharmacological basis of therapeutics; Infectious diseases, microbiology and parasitology; Medical ethics; Public health; and Evidence-based medicine - clinical epidemiology...
May 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28727258/changing-systems-through-effective-teams-a-role-for-simulation
#13
Elizabeth D Rosenman, Rosemarie Fernandez, Ambrose H Wong, Michael Cassara, Dylan D Cooper, Maybelle Kou, Torrey A Laack, Ivette Motola, Jessica R Parsons, Benjamin R Levine, James A Grand
Teams are the building blocks of the healthcare system, with growing evidence linking the quality of health care to team effectiveness, and team effectiveness to team training. Simulation has been identified as an effective modality for team training and assessment. Despite this, there are gaps in methodology, measurement, and implementation that prevent maximizing the impact of simulation modalities on team performance. As part of the 2017 Academic Emergency Medicine Consensus Conference "Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes," we explored the impact of simulation on various aspects of team effectiveness...
July 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28719221/biosimilars-biologics-that-meet-patients-needs-and-healthcare-economics
#14
Mark McCamish, William Yoon, James McKay
Biologics have revolutionized medical care, yet uniform access to these effective medicines remains difficult due to the increasing costs of healthcare. As patent exclusivity on the early biologics wanes, regulatory and legal systems are adapting to bring competition to the field in the form of biosimilars. Biosimilars are biologics that offer the same clinical benefit in one or more of the same indications as the reference biologic drug and bring competition to the biologics space. Legislation creating a pathway resulting in the first US approvals of biosimilars has been in place since 2010, but the regulatory methodology and science of evaluating the sameness of two biologics has been in use for decades...
September 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/28631257/the-validity-and-responsiveness-of-isometric-lower-body-multi-joint-tests-of-muscular-strength-a-systematic-review
#15
REVIEW
David Drake, Rodney Kennedy, Eric Wallace
BACKGROUND: Researchers and practitioners working in sports medicine and science require valid tests to determine the effectiveness of interventions and enhance understanding of mechanisms underpinning adaptation. Such decision making is influenced by the supportive evidence describing the validity of tests within current research. The objective of this study is to review the validity of lower body isometric multi-joint tests ability to assess muscular strength and determine the current level of supporting evidence...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28626815/part-time-versus-full-time-occlusion-therapy-for-treatment-of-amblyopia-a%C3%A2-meta-analysis
#16
REVIEW
Negareh Yazdani, Ramin Sadeghi, Hamed Momeni-Moghaddam, Leili Zarifmahmoudi, Asieh Ehsaei, Brendan T Barrett
PURPOSE: To compare full-time occlusion (FTO) and part-time occlusion (PTO) therapy in the treatment of amblyopia, with the secondary aim of evaluating the minimum number of hours of part-time patching required for maximal effect from occlusion. METHODS: A literature search was performed in PubMed, Scopus, Science Direct, Ovid, Web of Science and Cochrane library. Methodological quality of the literature was evaluated according to the Oxford Center for Evidence Based Medicine and modified Newcastle-Ottawa scale...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28619465/a-systematic-review-of-soft-to-hard-tissue-ratios-in-orthognathic-surgery-part-iv-3d-analysis-is-there-evidence
#17
Sergio Olate, Carlos Zaror, Maurice Y Mommaerts
OBJECTIVE: The objective of this study was to determine the soft-to-hard tissue ratio using 3D analysis in different types of orthognathic surgery. MATERIAL AND METHODS: A systematic search for relevant studies published in different languages through December 2016 was performed in the Medline, Embase, Lilacs, Scopus, and Science Direct databases. Additional studies were identified by reference analysis. The methodological quality of the included studies was evaluated using the method proposed by the Effective Public Health Practice Project...
May 17, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28599011/medicine-performing-arts-and-science-dancing-to-the-same-tune
#18
EDITORIAL
Bronwen J Ackermann
A substantial period of time has been spent developing rigorous quantitative scientific approaches to inform medical practice (evidence-based practice). While this process has been important for many medical breakthroughs, and continues to play a critical role in medical and scientific research, it was felt to cause a medical shift away from the individual patient, as practitioners focussed more on the method of practice than the person themselves. However, following this period when a preponderance of attention was paid to quantitative studies, the tide has now turned back to integrating this knowledge with the clinical skills and expertise of medical practitioners...
June 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/28512066/use-of-electroencephalography-brain-computer-interface-systems-as-a-rehabilitative-approach-for-upper-limb-function-after-a-stroke-a-systematic-review
#19
REVIEW
Esther Monge-Pereira, Jaime Ibañez-Pereda, Isabel M Alguacil-Diego, Jose I Serrano, María P Spottorno-Rubio, Francisco Molina-Rueda
BACKGROUND: Brain-computer interface (BCI) systems have been suggested as a promising tool for neurorehabilitation. However, to date, there is a lack of homogeneous findings. Furthermore, no systematic reviews have analyzed the degree of validation of these interventions for upper limb (UL) motor rehabilitation poststroke. OBJECTIVES: The study aims were to compile all available studies that assess an UL intervention based on an electroencephalography (EEG) BCI system in stroke; to analyze the methodological quality of the studies retrieved; and to determine the effects of these interventions on the improvement of motor abilities...
May 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28472414/evidence-based-review-on-temporomandibular-disorders-among-musicians
#20
M K A van Selms, J Ahlberg, F Lobbezoo, C M Visscher
Background: Playing a musical instrument that loads the masticatory system has frequently been linked to temporomandibular disorders (TMDs). Previous literature reviews on this topic do not conform to the current standards of evidence-based medicine. Aims: To investigate the effects of playing a musical instrument (i.e. violin/viola and wind instruments) or singing on the presence of TMDs, based on evidence derived from observational studies. Methods: Databases of Medline, Web of Science and Google Scholar were searched using MeSH and other relevant terms...
July 1, 2017: Occupational Medicine
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