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Methodology, evidence-based medicine, science

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https://www.readbyqxmd.com/read/27858864/can-aidi-injection-restore-cellular-immunity-and-improve-clinical-efficacy-in-non-small-cell-lung-cancer-patients-treated-with-platinum-based-chemotherapy-a-meta-analysis-of-17-randomized-controlled-trials-following-the-prisma-guidelines
#1
Zheng Xiao, Chengqiong Wang, Yongping Sun, Nana Li, Jing Li, Ling Chen, Xingsheng Yao, Jie Ding, Hu Ma
BACKGROUND: Aidi injection is an adjuvant chemotherapy drug commonly used in China. Can Aidi injection restore the cellular immunity and improve the clinical efficacy in non-small-cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy? There is a lack of strong evidence to prove it. To further reveal it, we systematically evaluated all related studies. We collected all studies about the clinical efficacy and cellular immunity of Aidi injection plus platinum-based chemotherapy for NSCLC in Medline, Embase, Web of Science, China national knowledge infrastructure database (CNKI), Chinese Scientific Journals Full-Text Database (VIP), Wanfang, China biological medicine database (CBM) (established to June 2015), Cochrane Central Register of Controlled Trials (CCRCT) (June 2015), Chinese clinical trial registry, and US-clinical trials (June 2015)...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27802480/association-of-industry-sponsorship-with-outcomes-of-nutrition-studies-a-systematic-review-and-meta-analysis
#2
Nicholas Chartres, Alice Fabbri, Lisa A Bero
Importance: Food industry sponsorship of nutrition research may bias research reports, systematic reviews, and dietary guidelines. Objective: To determine whether food industry sponsorship is associated with effect sizes, statistical significance of results, and conclusions of nutrition studies with findings that are favorable to the sponsor and, secondarily, to determine whether nutrition studies differ in their methodological quality depending on whether they are industry sponsored...
December 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27731292/treatments-for-hyperemesis-gravidarum-and-nausea-and-vomiting-in-pregnancy-a-systematic-review-and-economic-assessment
#3
Amy O'Donnell, Catherine McParlin, Stephen C Robson, Fiona Beyer, Eoin Moloney, Andrew Bryant, Jennifer Bradley, Colin Muirhead, Catherine Nelson-Piercy, Dorothy Newbury-Birch, Justine Norman, Emma Simpson, Brian Swallow, Laura Yates, Luke Vale
BACKGROUND: Nausea and vomiting in pregnancy (NVP) affects up to 85% of all women during pregnancy, but for the majority self-management suffices. For the remainder, symptoms are more severe and the most severe form of NVP - hyperemesis gravidarum (HG) - affects 0.3-1.0% of pregnant women. There is no widely accepted point at which NVP becomes HG. OBJECTIVES: This study aimed to determine the relative clinical effectiveness and cost-effectiveness of treatments for NVP and HG...
October 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27659582/beyond-the-anticipatory-corpse-medicine-power-and-the-care-of-the-dying-a-theoretical-and-methodological-intervention-into-the-sociology-of-brain-implant-surgery
#4
Black Hawk Hancock, Daniel R Morrison
Drawing on and extending the Foucaultian philosophical framework that Jeffrey Bishop develops in his masterful book, The Anticipatory Corpse: Medicine, Power, and the Care of the Dying, we undertake a sociological analysis of the neurological procedure-deep brain stimulation (DBS)-which implants electrodes in the brain, powered by a pacemaker-like device, for the treatment of movement disorders. Following Bishop's work, we carry out this analysis through a two-fold strategy. First, we examine how a multidisciplinary team evaluates candidates for this implant at a major medical center...
September 22, 2016: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/27623692/immunocap%C3%A2-isac-and-microtest-for-multiplex-allergen-testing-in-people-with-difficult-to-manage-allergic-disease-a-systematic-review-and-cost-analysis
#5
Marie Westwood, Bram Ramaekers, Shona Lang, Nigel Armstrong, Caro Noake, Shelley de Kock, Manuela Joore, Johan Severens, Jos Kleijnen
BACKGROUND: Allergy is a form of immune-mediated exaggerated sensitivity (hypersensitivity) to a substance that is either inhaled, swallowed, injected or comes into contact with the skin. Foreign substances that provoke allergies are called allergens. It has been claimed that multiplex allergen testing may help in diagnosing the cause of symptoms in patients with an unclear cause of allergy or who are allergic to more than one substance. OBJECTIVES: To evaluate multiplex allergen testing [devices that can measure the presence of multiple immunoglobulin E (IgE) antibodies in a patient's blood at the same time], by assessing (1) clinical effectiveness (allergy symptoms, incidence of acute exacerbations, mortality, adverse events of testing and treatment, health-care presentations or admissions, health-related quality of life); (2) effects on treatment (diet, immunotherapy medications, other potential testing); (3) any additional diagnostic information provided by multiplex allergen testing; and (4) cost-effectiveness (cost of different assessment strategies)...
September 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27618719/a-systematic-review-of-soft-to-hard-tissue-ratios-in-orthognathic-surgery-part-iii-double-jaw-surgery-procedures
#6
Sergio Olate, Carlos Zaror, John N Blythe, Maurice Y Mommaerts
OBJECTIVE: The aim was to determine the soft-to-hard tissue ratios in profile view in bimaxillary orthognathic surgical corrections. MATERIAL AND METHODS: A systematic review of studies published in different languages was performed by searching the Medline, Embase, Cochrane Library, Lilacs, Scopus, and Science Direct databases up to August 2015. Additional studies were identified by reference analyses. The methodological quality was evaluated using the instrument developed by the Effective Public Health Practice Project and the Level of Evidence using the Level of Evidence scale from the Oxford Centre for Evidence-based Medicine...
August 21, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27562656/acupuncture-for-stroke-rehabilitation
#7
REVIEW
Ai Yang, Hong Mei Wu, Jin-Ling Tang, Li Xu, Ming Yang, Guan J Liu
BACKGROUND: Stroke is the second most common cause of death in the world and in China it has now become the main cause of death. It is also a main cause of adult disability and dependency. Acupuncture for stroke has been used in China for hundreds of years and is increasingly practiced in some Western countries. This is an update of the Cochrane review originally published in 2006 . OBJECTIVES: To determine the efficacy and safety of acupuncture therapy in people with subacute and chronic stroke...
August 26, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27536499/a-bibliometric-analysis-of-the-100-most-cited-articles-in-rhinoplasty
#8
Yashashwi Sinha, Fahad M Iqbal, John N Spence, Bruce Richard
INTRODUCTION: Citation analysis aims to quantify the importance and influence of a published article within its field. We performed a bibliometric analysis to determine the most highly cited articles within rhinoplasty and their impact on current practice. METHODS: The 100 most-cited articles relating to rhinoplasty, between and inclusive of January 1864 to September 2015, were extracted from Web of Science in October 2015. Title, source journal, publication year, total citations, average citations/year, type of article, level of evidence, country of origin, main focus, use of outcome measures, incorporation into "Selected Readings in Plastic Surgery," and funding status were recorded...
July 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27507769/population-based-precision-cancer-screening-a-symposium-on-evidence-epidemiology-and-next-steps
#9
Pamela M Marcus, Nora Pashayan, Timothy R Church, V Paul Doria-Rose, Michael K Gould, Rebecca A Hubbard, Michael Marrone, Diana L Miglioretti, Paul D Pharoah, Paul F Pinsky, Katherine A Rendle, Hilary A Robbins, Megan C Roberts, Betsy Rolland, Mark Schiffman, Jasmin A Tiro, Ann G Zauber, Deborah M Winn, Muin J Khoury
Precision medicine, an emerging approach for disease treatment that takes into account individual variability in genes, environment, and lifestyle, is under consideration for preventive interventions, including cancer screening. On September 29, 2015, the National Cancer Institute sponsored a symposium entitled "Precision Cancer Screening in the General Population: Evidence, Epidemiology, and Next Steps". The goal was two-fold: to share current information on the evidence, practices, and challenges surrounding precision screening for breast, cervical, colorectal, lung, and prostate cancers, and to allow for in-depth discussion among experts in relevant fields regarding how epidemiology and other population sciences can be used to generate evidence to inform precision screening strategies...
November 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27504820/effectiveness-of-the-transpalatal-arch-in-controlling-orthodontic-anchorage-in-maxillary-premolar-extraction-cases-a-systematic-review-and-meta-analysis
#10
Samira Diar-Bakirly, Murilo Fernando Neuppmann Feres, Humam Saltaji, Carlos Flores-Mir, Tarek El-Bialy
OBJECTIVE: To evaluate the effectiveness of the transpalatal arch (TPA) as an anchorage device in preventing maxillary molar mesialization during retraction of the anterior teeth after premolar extraction. MATERIALS AND METHODS: This systematic review intended to include patients indicated for upper premolar bilateral extraction and subsequent retraction of anterior teeth, considering the use of TPA as an anchorage tool in one of the treatment groups. The search was systematically performed, up to April 2015, in the following electronic databases: Medline, Embase, and all evidence-based medicine reviews via OVID, Cochrane Library, Scopus, PubMed, and Web of Science...
August 9, 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/27418334/-do-not-do-recommendations-of-the-spanish-society-of-anaesthesiology-critical-care-and-pain-therapy-commitment-to-quality-by-scientific-societies-project
#11
L Quecedo Gutiérrez, R Ruiz Abascal, J M Calvo Vecino, A I Peral García, E Matute González, L E Muñoz Alameda, E Guasch Arévalo, F Gilsanz Rodríguez
In April 2013 the Ministry of Health (MSSSI) adopted the project called "Commitment to Quality by Scientific Societies in Spain", in response to social and professional demands for sustainability of the health system. The initiative is part of the activities of the Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System, and is coordinated jointly by the Quality and Cohesion Department, the Aragon Institute of Health Sciences (IACS), and the Spanish Society of Internal Medicine (SEMI)...
July 11, 2016: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/27354804/randomized-controlled-trials-a-matter-of-design
#12
REVIEW
Peter Markus Spieth, Anne Sophie Kubasch, Ana Isabel Penzlin, Ben Min-Woo Illigens, Kristian Barlinn, Timo Siepmann
Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form the basis for translating research data into clinical practice. This review summarizes commonly applied designs and quality indicators of RCTs to provide guidance in interpreting and critically evaluating clinical research data. It further reflects on the principle of equipoise and its practical applicability to clinical science with an emphasis on critical care and neurological research. We performed a review of educational material, review articles, methodological studies, and published clinical trials using the databases MEDLINE, PubMed, and ClinicalTrials...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27141686/-investigation-methodology-and-application-on-scientific-and-technological-personnel-of-traditional-chinese-medical-resources-based-on-data-from-chinese-scientific-research-paper
#13
Hai-yan Li, Yuan-hai Li, Yang Yang, Fang-zhou Liu, Jing Wang, Ye Tian, Ce Yang, Yang Liu, Meng Li, Sun Li-ying
The aim of this study is to identify the present status of the scientific and technological personnel in the field of traditional Chinese medicine (TCM) resource science. Based on the data from Chinese scientific research paper, an investigation regarding the number of the personnel, the distribution, their output of paper, their scientific research teams, high-yield authors and high-cited authors was conducted. The study covers seven subfields of traditional Chinese medicine identification, quality standard, Chinese medicine cultivation, harvest processing of TCM, market development and resource protection and resource management, as well as 82 widely used Chinese medicine species, such as Ginseng and Radix Astragali...
December 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/27012576/removable-functional-appliances-effective-in-patients-with-class-ii-malocclusions
#14
COMMENT
Parthasarathy Madurantakam
DATA SOURCES: Medline (Pubmed), Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Google Scholar, Web of Science, Evidence-based Medicine, Scopus, LILACS database, Ovid database, Bibliografia Brasileira de Odontolgogia, Bandolier, Atypon Link, African Journals Online, ProQuest, Conference Paper Index, German National Library of Medicine, metaRegister of Controlled Trials. STUDY SELECTION: Randomised Controlled Trials (RCT) or prospective Controlled Clinical Trials (pCCT) in patients with Class II malocclusions that compared at least one removable functional appliance (RFA) with a non-intervention control...
March 2016: Evidence-based Dentistry
https://www.readbyqxmd.com/read/27006666/validity-and-reliability-of-published-comprehensive-theory-of-mind-tests-for-normal-preschool-children-a-systematic-review
#15
Seyyede Zohreh Ziatabar Ahmadi, Shohreh Jalaie, Hassan Ashayeri
OBJECTIVE: Theory of mind (ToM) or mindreading is an aspect of social cognition that evaluates mental states and beliefs of oneself and others. Validity and reliability are very important criteria when evaluating standard tests; and without them, these tests are not usable. The aim of this study was to systematically review the validity and reliability of published English comprehensive ToM tests developed for normal preschool children. METHOD: We searched MEDLINE (PubMed interface), Web of Science, Science direct, PsycINFO, and also evidence base Medicine (The Cochrane Library) databases from 1990 to June 2015...
September 2015: Iranian Journal of Psychiatry
https://www.readbyqxmd.com/read/26967459/effects-of-acupuncture-in-anesthesia-for-craniotomy-a-meta-analysis
#16
Sven Asmussen, Dirk M Maybauer, Jiande D Chen, John F Fraser, Michael H Toon, Rene Przkora, Kristofer Jennings, Marc O Maybauer
BACKGROUND: Acupuncture treatment has been used in China for >2500 years, and at present it is used worldwide as a form of analgesia in patients with acute and chronic pain. Furthermore, acupuncture is regularly used not only as a single anesthetic technique but also as a supplement or in addition to general anesthesia (GA). OBJECTIVES: The aim of this systematic review and meta-analysis was to assess the level of evidence for the clinical use of acupuncture in addition to GA in patients undergoing craniotomy...
March 10, 2016: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/26955280/simulation-based-assessments-in-health-professional-education-a-systematic-review
#17
REVIEW
Tayne Ryall, Belinda K Judd, Christopher J Gordon
INTRODUCTION: The use of simulation in health professional education has increased rapidly over the past 2 decades. While simulation has predominantly been used to train health professionals and students for a variety of clinically related situations, there is an increasing trend to use simulation as an assessment tool, especially for the development of technical-based skills required during clinical practice. However, there is a lack of evidence about the effectiveness of using simulation for the assessment of competency...
2016: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/26942349/extracorporeal-membrane-oxygenation-in-pregnant-and-postpartum-women-with-h1n1-related-acute-respiratory-distress-syndrome-a-systematic-review-and-meta-analysis
#18
REVIEW
Antonio F Saad, Mahbubur Rahman, Dirk M Maybauer, John F Fraser, Maged M Costantine, Luis D Pacheco, Marc O Maybauer
OBJECTIVE: To assess available evidence regarding the use of extracorporeal membrane oxygenation (ECMO) in pregnant and postpartum women with acute respiratory distress syndrome (ARDS) secondary to H1N1 infection. DATA SOURCES: Databases from MEDLINE (U.S. National Library of Medicine, 1946 to April 1, 2015), the Cochrane Library Controlled Trials Register, ClinicalTrials.gov, and Web of Science were queried for studies on ECMO in pregnant or postpartum patients with ARDS...
February 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26893401/strategies-for-implementing-implementation-science-a-methodological-overview
#19
REVIEW
Margaret A Handley, Anuradha Gorukanti, Adithya Cattamanchi
A key reason for the consistent gaps between evidence and practice across all areas of medicine is that there has been little attempt to identify or target factors critical for successful implementation of an evidence-based intervention. There is either no explicit implementation strategy or the strategy is based on a best guess rather than on a systematic assessment of crucial barriers and enablers. A different approach is needed to close the evidence-practice gap and thereby achieve the triple aim of improved health, improved patient experience and reduced healthcare costs...
September 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/26859247/nutritional-screening-in-hospitalized-pediatric-patients-a-systematic-review
#20
Adriana Fonseca Teixeira, Kátia Danielle Araújo Lourenço Viana
OBJECTIVE: This systematic review aimed to verify the available scientific evidence on the clinical performance and diagnostic accuracy of nutritional screening tools in hospitalized pediatric patients. DATA SOURCE: A search was performed in the Medline (National Library of Medicine United States), LILACS (Latin American and Caribbean Health Sciences), PubMed (US National Library of Medicine National Institutes of Health), in the SCIELO (Scientific Electronic Library Online), through CAPES portal (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior), bases Scopus e Web of Science...
July 2016: Jornal de Pediatria
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